Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0585 | 0.1198 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0038 | 0.0393 | 0.0599 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0088 | 0.1392 | 0.1392 |
Echinococcus granulosus | zinc finger protein | 0.0024 | 0.0125 | 0.0125 |
Brugia malayi | Bromodomain containing protein | 0.0082 | 0.1287 | 0.1255 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0037 | 0.0037 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0037 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0115 | 0.0115 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0268 | 0.0268 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0047 | 0.0585 | 0.0927 |
Giardia lamblia | GTOR | 0.0047 | 0.0585 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0049 | 0.0626 | 0.0626 |
Brugia malayi | jmjC domain containing protein | 0.01 | 0.1645 | 0.1614 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0075 | 0.0075 |
Schistosoma mansoni | zinc finger protein | 0.0024 | 0.0125 | 0.0125 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0585 | 0.1198 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0063 | 0.0905 | 0.0871 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.0376 | 0.034 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0047 | 0.0585 | 1 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.015 | 0.2634 | 0.2634 |
Brugia malayi | Carboxylesterase family protein | 0.0088 | 0.1392 | 0.1361 |
Onchocerca volvulus | 0.0088 | 0.1392 | 0.2614 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0343 | 0.067 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0268 | 0.0232 |
Leishmania major | sterol C-24 reductase, putative | 0.005 | 0.0634 | 0.1006 |
Brugia malayi | Carboxylesterase family protein | 0.0088 | 0.1392 | 0.1361 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0022 | 0.0085 | 0.0048 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0396 | 0.0396 |
Schistosoma mansoni | acetylcholinesterase | 0.0088 | 0.1392 | 0.1392 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0422 | 0.0422 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0317 | 0.5976 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.015 | 0.0249 |
Onchocerca volvulus | 0.0088 | 0.1392 | 0.2614 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0088 | 0.1392 | 0.1392 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0219 | 0.4007 | 0.3985 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0397 | 0.0397 |
Echinococcus granulosus | acetylcholinesterase | 0.0519 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0088 | 0.1392 | 0.1392 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.02 | 0.0357 |
Onchocerca volvulus | 0.0249 | 0.461 | 1 | |
Brugia malayi | Pre-SET motif family protein | 0.0219 | 0.4007 | 0.3985 |
Loa Loa (eye worm) | carboxylesterase | 0.0088 | 0.1392 | 0.1361 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0045 | 0.0533 | 0.0835 |
Echinococcus multilocularis | zinc finger protein | 0.0024 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1392 | 0.1361 |
Brugia malayi | hypothetical protein | 0.0088 | 0.1392 | 0.1361 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0037 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0519 | 1 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0046 | 0.0557 | 0.1138 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0585 | 0.0927 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0343 | 0.067 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0045 | 0.0533 | 0.084 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0422 | 0.0422 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0088 | 0.1392 | 0.1392 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0047 | 0.0585 | 0.0585 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0088 | 0.1392 | 0.1392 |
Onchocerca volvulus | 0.0088 | 0.1392 | 0.2614 | |
Brugia malayi | Carboxylesterase family protein | 0.0088 | 0.1392 | 0.1361 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0206 | 0.0369 |
Mycobacterium ulcerans | hypothetical protein | 0.0167 | 0.2979 | 1 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0031 | 0.0254 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1392 | 0.1361 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0151 | 0.025 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0397 | 0.657 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0397 | 0.0397 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0254 | 0.0254 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0031 | 0.0254 | 0.0254 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0037 | 0.0037 |
Trypanosoma cruzi | sterol C-24 reductase, putative | 0.005 | 0.0634 | 0.1006 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0031 | 0.0254 | 0.0218 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0206 | 0.0369 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0343 | 0.067 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0151 | 0.025 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0047 | 0.0585 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0392 | 0.0777 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0047 | 0.0585 | 0.0923 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0038 | 0.0393 | 0.0599 |
Echinococcus multilocularis | lamin b receptor | 0.005 | 0.0634 | 0.0634 |
Trichomonas vaginalis | set domain proteins, putative | 0.0249 | 0.461 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1126 | 0.1093 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0088 | 0.1392 | 0.2964 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0046 | 0.0557 | 0.83 |
Loa Loa (eye worm) | acetyltransferase | 0.015 | 0.2634 | 0.2607 |
Loa Loa (eye worm) | carboxylesterase | 0.0519 | 1 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0037 | 0.0005 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0046 | 0.0557 | 0.1138 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0254 | 0.0475 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0397 | 0.657 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0317 | 0.5976 | 1 |
Onchocerca volvulus | 0.0052 | 0.068 | 0.0977 | |
Echinococcus granulosus | BC026374 protein S09 family | 0.0088 | 0.1392 | 0.1392 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0519 | 1 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.01 | 0.1645 | 0.1645 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0626 | 0.0591 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0075 | 0.0038 |
Echinococcus multilocularis | neuroligin | 0.0088 | 0.1392 | 0.1392 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.0275 | 0.052 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.015 | 0.264 | 0.4386 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0392 | 0.0777 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.068 | 0.0645 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1392 | 0.1361 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0397 | 0.0397 |
Loa Loa (eye worm) | carboxylesterase | 0.0088 | 0.1392 | 0.1361 |
Echinococcus multilocularis | acetylcholinesterase | 0.0519 | 1 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0167 | 0.2979 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.01 | 0.1645 | 0.1645 |
Toxoplasma gondii | hypothetical protein | 0.0051 | 0.0664 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0519 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0088 | 0.1392 | 0.4608 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0245 | 0.0245 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0397 | 0.657 |
Brugia malayi | Carboxylesterase family protein | 0.0519 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0519 | 1 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0047 | 0.0585 | 0.055 |
Brugia malayi | jmjC domain containing protein | 0.0039 | 0.0422 | 0.0387 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0254 | 0.346 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0049 | 0.0626 | 0.0626 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0519 | 1 | 1 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0046 | 0.0557 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0585 | 0.1198 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.015 | 0.0249 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0317 | 0.5976 | 1 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0397 | 0.0361 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0237 | 0.0201 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0602 | 0.0602 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.015 | 0.264 | 0.4383 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0047 | 0.0585 | 0.0923 |
Leishmania major | C-14 sterol reductase, putative | 0.005 | 0.0634 | 0.1006 |
Echinococcus granulosus | tumor protein p63 | 0.0355 | 0.6729 | 0.6729 |
Trypanosoma cruzi | C-14 sterol reductase, putative | 0.005 | 0.0634 | 0.1006 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.015 | 0.264 | 0.4383 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0052 | 0.068 | 0.068 |
Trypanosoma brucei | C-14 sterol reductase, putative | 0.005 | 0.0634 | 0.101 |
Echinococcus granulosus | acetylcholinesterase | 0.0519 | 1 | 1 |
Echinococcus granulosus | peregrin | 0.0037 | 0.0376 | 0.0376 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0066 | 0.0967 | 0.0967 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0031 | 0.0254 | 0.0254 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0088 | 0.1392 | 0.1392 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0268 | 0.3693 |
Giardia lamblia | PHD finger protein 15 | 0.0031 | 0.0254 | 0.3959 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0609 | 0.0574 |
Echinococcus granulosus | jumonji domain containing protein | 0.0043 | 0.0493 | 0.0493 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0343 | 0.067 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0088 | 0.1392 | 0.4608 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0088 | 0.1392 | 0.1392 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0268 | 0.0268 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.0382 | 0.0382 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0343 | 0.067 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.004 | 0.0436 | 0.7276 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0343 | 0.067 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0254 | 0.0218 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0602 | 0.0602 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0039 | 0.0422 | 0.0422 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0047 | 0.0585 | 0.055 |
Loa Loa (eye worm) | hypothetical protein | 0.0519 | 1 | 1 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0047 | 0.0585 | 0.0923 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0602 | 0.0602 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0585 | 0.0923 |
Echinococcus granulosus | neuroligin | 0.0088 | 0.1392 | 0.1392 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0602 | 0.0602 |
Brugia malayi | Bromodomain containing protein | 0.0044 | 0.0518 | 0.0483 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0039 | 0.0422 | 0.0387 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.004 | 0.0436 | 0.7276 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.015 | 0.2634 | 0.2607 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0396 | 0.0396 |
Schistosoma mansoni | jumonji domain containing protein | 0.008 | 0.1233 | 0.1233 |
Schistosoma mansoni | gliotactin | 0.0088 | 0.1392 | 0.1392 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0691 | 0.0656 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.02 | 0.0357 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0054 | 0.0728 | 0.1163 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0602 | 0.0602 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.9295 | 0.9292 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0585 | 0.0585 |
Echinococcus multilocularis | peregrin | 0.0037 | 0.0376 | 0.0376 |
Onchocerca volvulus | 0.0031 | 0.0268 | 0.0034 | |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0037 | 0.0037 |
Schistosoma mansoni | Lamin B receptor (ERG24) | 0.005 | 0.0634 | 0.0634 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1392 | 0.1361 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0397 | 0.0397 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0206 | 0.0369 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0049 | 0.0626 | 0.0626 |
Echinococcus granulosus | carboxylesterase 5A | 0.0519 | 1 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0317 | 0.5976 | 1 |
Echinococcus granulosus | lamin b receptor | 0.005 | 0.0634 | 0.0634 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0254 | 0.0218 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0022 | 0.0088 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1392 | 0.1361 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0035 | 0.0343 | 0.4888 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0115 | 0.0115 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0043 | 0.0493 | 0.0493 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0115 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0569 | 0.0534 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0602 | 0.0567 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0447 | 0.0412 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0143 | 0.2502 | 0.2502 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0066 | 0.0967 | 0.0967 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.015 | 0.0249 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0151 | 0.025 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0037 | 0.0037 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.0254 | 0.4169 |
Brugia malayi | Carboxylesterase family protein | 0.0088 | 0.1392 | 0.1361 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0088 | 0.1392 | 0.1392 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0254 | 0.346 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0088 | 0.1392 | 0.2964 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1392 | 0.1361 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0088 | 0.1392 | 0.4608 |
Plasmodium falciparum | phd finger protein, putative | 0.0031 | 0.0254 | 0.5442 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0045 | 0.0533 | 0.0835 |
Trypanosoma cruzi | sterol C-24 reductase, putative | 0.005 | 0.0634 | 0.1006 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0397 | 0.657 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0447 | 0.0897 |
Schistosoma mansoni | bromodomain containing protein | 0.007 | 0.1042 | 0.1042 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0049 | 0.0626 | 0.0626 |
Trypanosoma cruzi | C-14 sterol reductase, putative | 0.005 | 0.0634 | 0.1006 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0088 | 0.1392 | 0.1392 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0038 | 0.0393 | 0.0604 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0392 | 0.0777 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0046 | 0.0557 | 0.83 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0585 | 0.0585 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0088 | 0.1392 | 0.4608 |
Onchocerca volvulus | 0.0088 | 0.1392 | 0.2614 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0343 | 0.067 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0045 | 0.0533 | 0.0835 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0602 | 0.0567 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0151 | 0.025 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.0436 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0088 | 0.1392 | 0.1392 |
Onchocerca volvulus | 0.0088 | 0.1392 | 0.2614 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0392 | 0.0777 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0602 | 0.0602 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1392 | 0.1361 |
Echinococcus multilocularis | tumor protein p63 | 0.0355 | 0.6729 | 0.6729 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0046 | 0.0557 | 0.0557 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.015 | 0.2634 | 0.2634 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0268 | 0.445 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0392 | 0.0777 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0268 | 0.0268 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0602 | 0.0602 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | > 100 uM | Cytotoxicity against Homo sapiens (human) HOP62 cells assessed as growth inhibition after 48 hr by trypan blue exclusion assay | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.