Detailed information for compound 1831077

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 473.545 | Formula: C22H27N5O5S
  • H donors: 0 H acceptors: 6 LogP: 2.97 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(COC(=O)N1CCC(CC1)n1ncc2c1ncnc2Oc1ccc(cc1)S(=O)(=O)C)C
  • InChi: 1S/C22H27N5O5S/c1-15(2)13-31-22(28)26-10-8-16(9-11-26)27-20-19(12-25-27)21(24-14-23-20)32-17-4-6-18(7-5-17)33(3,29)30/h4-7,12,14-16H,8-11,13H2,1-3H3
  • InChiKey: AQWSSQRBNHYWBP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0028 0.0104 0.0104
Brugia malayi hypothetical protein 0.0005 0.0007 0.0058
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0264 0.2293
Schistosoma mansoni glycerol-3-phosphate dehydrogenase 0.0198 0.0819 0.0818
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0027 0.0026
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.0007 0.0006
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0146 0.1269
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0027 0.0235
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0293 0.0293
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0005 0.0004 0.0011
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.004 0.0151 0.1839
Schistosoma mansoni tankyrase 0.0277 0.1155 0.1154
Schistosoma mansoni sarm1 0.0025 0.0087 0.0087
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Brugia malayi nuclear receptor NHR-88 0.001 0.0027 0.0235
Toxoplasma gondii ABC1 family protein 0.0042 0.0161 0.1965
Echinococcus multilocularis deoxyribonuclease 1 2 0.0004 0.0001 0.0001
Brugia malayi WGR domain containing protein 0.004 0.0151 0.132
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0293 0.0293
Echinococcus granulosus liprin beta 1 0.0025 0.0087 0.0758
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Echinococcus granulosus FTZ F1 alpha 0.001 0.0027 0.0233
Brugia malayi nuclear hormone receptor family member odr-7 0.0005 0.0004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Schistosoma mansoni poly [ADP-ribose] polymerase 0.004 0.0151 0.015
Echinococcus multilocularis muscleblind protein 0.0169 0.0696 0.1808
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0161
Schistosoma mansoni hypothetical protein 0.0025 0.0087 0.0087
Schistosoma mansoni ap endonuclease 0.0019 0.0066 0.0065
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0293 0.0293
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0027 0.0235
Trypanosoma cruzi FAD dependent oxidoreductase, putative 0.0198 0.0819 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0264 0.3226
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0087 0.5419
Onchocerca volvulus 0.0005 0.0004 0.0036
Entamoeba histolytica anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative 0.0198 0.0819 1
Brugia malayi TAR-binding protein 0.0073 0.0293 0.2564
Schistosoma mansoni hypothetical protein 0.0039 0.0149 0.0149
Echinococcus multilocularis poly (ADP ribose) polymerase 0.004 0.0151 0.0392
Brugia malayi Neurabin protein 1 0.0025 0.0087 0.0765
Toxoplasma gondii exonuclease III APE 0.0019 0.0066 0.08
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0027 0.0255
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0005 0.0004 0.0004
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0027 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0161 0.1965
Echinococcus multilocularis muscleblind protein 1 0.0169 0.0696 0.1808
Echinococcus granulosus GPCR family 2 0.0035 0.013 0.1125
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0027 0.0235
Entamoeba histolytica zinc finger protein, putative 0.004 0.0151 0.1839
Leishmania major hypothetical protein, conserved 0.0198 0.0819 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0025 0.0087 0.1062
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 20 0.0198 0.0819 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0161
Echinococcus granulosus Nuclear hormone receptor HR96 0.0005 0.0004 0.0036
Echinococcus granulosus Nuclear hormone receptor HR96 0.0005 0.0004 0.0036
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0027 0.007
Onchocerca volvulus 0.0049 0.0189 0.1824
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.004 0.0151 0.1839
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0087 0.5419
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0161 0.0096
Schistosoma mansoni hypothetical protein 0.0035 0.013 0.0129
Brugia malayi sterile alpha and TIR motif containing protein 1 isoform a 0.0025 0.0087 0.0765
Mycobacterium tuberculosis Probable D-amino acid oxidase Aao 0.2175 0.9165 1
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0198 0.0819 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0027 0.007
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0066 0.5
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0027 0.0255
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0198 0.0819 1
Echinococcus granulosus tar DNA binding protein 0.0073 0.0293 0.2541
Schistosoma mansoni hypothetical protein 0.0035 0.013 0.0129
Brugia malayi steroid hormone receptor 0.001 0.0027 0.0235
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0293 0.0293
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0066 0.0071
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0004 0.0001 0.0031
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0007 0.0058
Schistosoma mansoni fad oxidoreductase 0.0198 0.0819 0.0818
Brugia malayi hypothetical protein 0.0238 0.0989 0.865
Schistosoma mansoni hypothetical protein 0.0035 0.013 0.0129
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0027 0.0026
Echinococcus granulosus tankyrase 0.0277 0.1153 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Onchocerca volvulus 0.0042 0.0161 0.1557
Loa Loa (eye worm) hypothetical protein 0.0198 0.0819 0.0818
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0293 0.0761
Giardia lamblia Kinase, NEK 0.0004 0.0001 0.0012
Echinococcus granulosus synaptojanin 1 0.0004 0.0001 0.0004
Brugia malayi Tnks protein 0.0275 0.1143 1
Schistosoma mansoni hypothetical protein 0.0025 0.0087 0.0087
Loa Loa (eye worm) beta-lactamase 0.0042 0.0161 0.0161
Brugia malayi nuclear hormone receptor 0.001 0.0027 0.0235
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0027 0.007
Leishmania major hypothetical protein, conserved 0.0028 0.0104 0.1266
Mycobacterium ulcerans thiamine biosynthesis oxidoreductase ThiO 0.0198 0.0819 0.0758
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0053 0.0207 0.1812
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0264 0.0264
Trypanosoma brucei poly(adp-ribose) polymerase 0.004 0.0151 0.1839
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0087
Schistosoma mansoni ap endonuclease 0.0019 0.0066 0.0065
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0264 0.3226
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.0445 0.389
Loa Loa (eye worm) hypothetical protein 0.0005 0.0007 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0293 0.0293
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0038 0.0328
Schistosoma mansoni fad oxidoreductase 0.0198 0.0819 0.0818
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0027 0.0026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0207 0.0538
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0005 0.0004 0.0262
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0027 0.007
Plasmodium falciparum tyrosine kinase-like protein 0.0025 0.0087 0.1062
Brugia malayi nuclear hormone receptor 0.0005 0.0004 0.0037
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0027 0.007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0027 0.0235
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0004 0.0001 0.0031
Onchocerca volvulus 0.0025 0.0087 0.0841
Trichomonas vaginalis ankyrin, putative 0.0004 0.0002 0.0102
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0005 0.0004 0.0004
Echinococcus multilocularis geminin 0.019 0.0788 0.2047
Echinococcus multilocularis nuclear receptor nhr 48 0.0005 0.0004 0.0011
Echinococcus granulosus muscleblind protein 0.0169 0.0696 0.6035
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0027 0.0233
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0109 0.0445 0.0444
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0005 0.0004 0.0036
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0004 0.0001 0.0001
Trichomonas vaginalis c2h2 zinc finger protein, putative 0.0025 0.0087 0.5419
Loa Loa (eye worm) hypothetical protein 0.0209 0.0868 0.0868
Brugia malayi hypothetical protein 0.0005 0.0007 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0027 0.0235
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Schistosoma mansoni thyroid hormone receptor 0.001 0.0027 0.0026
Brugia malayi conserved hypotetical protein 0.0005 0.0004 0.0037
Schistosoma mansoni hypothetical protein 0.019 0.0788 0.0788
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0161 0.1965
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0104 0.1266
Echinococcus granulosus nuclear receptor nhr 48 0.0005 0.0004 0.0036
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.013 0.0337
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0293 0.2564
Trypanosoma brucei palmitoyl acyltransferase 1, putative 0.0004 0.0001 0.0012
Onchocerca volvulus Tankyrase homolog 0.0249 0.1034 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0161
Echinococcus multilocularis liprin beta 1 0.0025 0.0087 0.0227
Echinococcus granulosus poly ADP ribose polymerase 1 0.004 0.0151 0.1309
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0146 0.038
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Mycobacterium leprae Probable cholesterol oxidase precursor ChoD (cholesterol-O2 oxidoreductase) 0.0198 0.0819 0.0668
Mycobacterium leprae Possible thiamine biosynthesis oxidoreductase ThiO 0.0198 0.0819 0.0668
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0027 0.0233
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0004 0.0001 0.0004
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0066 0.08
Echinococcus multilocularis sterile alpha and tir motif containing protein 0.0025 0.0087 0.0227
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0027 0.0233
Schistosoma mansoni thyroid hormone receptor 0.001 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0161 0.1965
Brugia malayi hypothetical protein 0.0025 0.0087 0.0765
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0027 0.007
Leishmania major glycerol-3-phosphate dehydrogenase-like protein 0.0198 0.0819 1
Onchocerca volvulus 0.0042 0.0161 0.1557
Brugia malayi latrophilin 2 splice variant baaae 0.0075 0.0299 0.2615
Chlamydia trachomatis D-amino acid dehydrogenase 0.0198 0.0819 0.5
Brugia malayi hypothetical protein 0.0025 0.0087 0.0765
Schistosoma mansoni ankyrin 23/unc44 0.0004 0.0001 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0066 0.08
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0038 0.0098
Brugia malayi Patatin-like phospholipase family protein 0.0004 0.0001 0.0013
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0027 0.0026
Brugia malayi hypothetical protein 0.0039 0.0149 0.1306
Brugia malayi beta-lactamase 0.0042 0.0161 0.1411
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0149 0.0388
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0005 0.0007 0.0057
Mycobacterium ulcerans hypothetical protein 0.0042 0.0161 0.0096
Echinococcus granulosus Sterile alpha motif SAM 0.0025 0.0087 0.0758
Toxoplasma gondii hypothetical protein 0.0198 0.0819 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0161 0.0175
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0027 0.0026
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0161 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), mitochondrial 0.0198 0.0819 1
Brugia malayi RNA binding protein 0.0073 0.0293 0.2564
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0005 0.0007 0.0017
Onchocerca volvulus 0.0025 0.0087 0.0841
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0161 0.0175
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0264 0.3226
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0149 0.1295
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0004 0.0001 0.0091
Brugia malayi tailless protein 0.0005 0.0004 0.0037
Echinococcus multilocularis synaptojanin 1 0.0004 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.004 0.0151 0.015
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0161 1
Onchocerca volvulus Dimethylglycine dehydrogenase, mitochondrial homolog 0.0198 0.0819 0.792
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0066 0.0572
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0005 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0025 0.0087 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0027 0.0235
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0198 0.0819 1
Brugia malayi Latrophilin receptor protein 2 0.0035 0.013 0.1135
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0198 0.0819 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0207 0.0207
Schistosoma mansoni hypothetical protein 0.0075 0.0299 0.0298
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Schistosoma mansoni zinc finger protein 0.0005 0.0004 0.0004
Onchocerca volvulus 0.0042 0.0161 0.1557
Brugia malayi nuclear receptor NHR-88 0.0005 0.0004 0.0037
Schistosoma mansoni hypothetical protein 0.0013 0.0038 0.0037
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0007 0.0058
Brugia malayi nuclear receptor RXR 0.0005 0.0007 0.0058
Mycobacterium ulcerans beta-lactamase 0.0042 0.0161 0.0096
Plasmodium falciparum FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0198 0.0819 1
Echinococcus granulosus liprin alpha 2 0.0025 0.0087 0.0758
Brugia malayi orphan nuclear receptor NR2E1 0.0005 0.0004 0.0037
Trypanosoma cruzi palmitoyl acyltransferase 1, putative 0.0004 0.0001 0.0012
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0027 0.0235
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0002 0.0102
Schistosoma mansoni nuclear receptor 0.0005 0.0004 0.0004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0027 0.0233
Loa Loa (eye worm) nuclear receptor NHR-67 0.0005 0.0004 0.0004
Loa Loa (eye worm) glycerol-3-phosphate dehydrogenase 0.0198 0.0819 0.0818
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0149 0.0149
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0005 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.0129
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0161
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.0989 0.2569
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0004 0.0001 0.0031
Echinococcus granulosus sterile alpha and tir motif containing protein 0.0025 0.0087 0.0758
Entamoeba histolytica hypothetical protein 0.004 0.0151 0.1839
Echinococcus granulosus stromal interaction molecule 1 0.0025 0.0087 0.0758
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0066 0.08
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0004 0.0001 0.0031
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.013 0.0337
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0027 0.0026
Schistosoma mansoni NAD dehydrogenase 0.0198 0.0819 0.0818
Entamoeba histolytica hypothetical protein 0.0039 0.0149 0.1818
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Schistosoma mansoni d-amino acid oxidase 0.2372 1 1
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0004 0.0001 0.0004
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0066 0.08
Loa Loa (eye worm) hypothetical protein 0.0198 0.0819 0.0818
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0104 0.1266
Trichomonas vaginalis Phospholipase C precursor, putative 0.0004 0.0001 0.0031
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0087
Loa Loa (eye worm) DR-78 0.0005 0.0004 0.0004
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0104 0.1266
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0027 0.0233
Echinococcus multilocularis GPCR, family 2 0.0035 0.013 0.0337
Brugia malayi nuclear receptor RXR 0.0005 0.0004 0.0037
Echinococcus granulosus geminin 0.019 0.0788 0.6833
Trichomonas vaginalis ion channel nompc, putative 0.0004 0.0001 0.0091
Loa Loa (eye worm) hypothetical protein 0.0169 0.0696 0.0696
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0207 0.1796
Entamoeba histolytica hypothetical protein 0.004 0.0151 0.1839
Entamoeba histolytica hypothetical protein 0.004 0.0151 0.1839
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0004 0.0001 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0027 0.0235
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.004 0.0151 0.0392
Entamoeba histolytica hypothetical protein 0.0039 0.0149 0.1818
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Mycobacterium tuberculosis Conserved protein 0.0042 0.0161 0.0175
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Echinococcus multilocularis traf and tnf receptor associated protein 0.0004 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0039 0.0149 0.1818
Schistosoma mansoni lip-related protein (liprin) alpha 0.0025 0.0087 0.0087
Loa Loa (eye worm) toll and interleukin 1 receptor domain-containing protein isoform f 0.0025 0.0087 0.0087
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0004 0.0001 0.0091
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0004 0.0001 0.0001
Echinococcus multilocularis stromal interaction molecule 1 0.0025 0.0087 0.0227
Toxoplasma gondii FAD-dependent glycerol-3-phosphate dehydrogenase 0.0198 0.0819 1
Leishmania major hypothetical protein, conserved 0.0042 0.0161 0.1965
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0027 0.0026
Brugia malayi CCR4 0.0004 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0005 0.0007 0.0006
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0104 0.1266
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0066 0.0171
Echinococcus granulosus traf and tnf receptor associated protein 0.0004 0.0001 0.0004
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0066 0.08
Schistosoma mansoni nuclear receptor 0.0005 0.0004 0.0004
Schistosoma mansoni nuclear hormone receptor 0.001 0.0027 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Mycobacterium ulcerans glycerol-3-phosphate dehydrogenase 0.0198 0.0819 0.0758
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0005 0.0004 0.0036
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0161 0.0161
Giardia lamblia Kinase, NEK 0.0004 0.0001 0.0012
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase, putative 0.0198 0.0819 1
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0066 0.4091
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0189 0.1653
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0005 0.0004 0.0273
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Echinococcus granulosus poly adp ribose polymerase 2 0.004 0.0151 0.1309
Brugia malayi hypothetical protein 0.0018 0.0062 0.0538
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0087 0.5419
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0027 0.0235
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0004 0.0001 0.0013
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Echinococcus granulosus thyroid hormone receptor alpha 0.0005 0.0004 0.0036
Schistosoma mansoni coup transcription factor 0.001 0.0027 0.0026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0161 0.0161
Brugia malayi hypothetical protein 0.0028 0.0104 0.091
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0004 0.0004
Echinococcus multilocularis Ankyrin 0.0004 0.0002 0.0004
Schistosoma mansoni ATP:guanidino kinase (Smc74) 0.0198 0.0819 0.0818
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0027 0.0026
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0066 0.08
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0027 0.0235
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Loa Loa (eye worm) hypothetical protein 0.0004 0.0002 0.0001
Schistosoma mansoni nuclear receptor nhr-48 0.0005 0.0004 0.0004
Trichomonas vaginalis unc-44 ankyrins, putative 0.0004 0.0001 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0004 0.0001 0.0091
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0161 0.1399
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0007 0.0006
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0004 0.0001 0.0031
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0268 0.1117 0.1219
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.004 0.0151 0.1839
Schistosoma mansoni hypothetical protein 0.0025 0.0087 0.0087
Brugia malayi RE18450p 0.0198 0.0819 0.7162
Echinococcus granulosus SAM domain containing protein 0.0025 0.0087 0.0758
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0066 1
Brugia malayi WGR domain containing protein 0.004 0.0151 0.132
Mycobacterium leprae PROBABLE D-AMINO ACID OXIDASE AAO 0.2372 1 1
Brugia malayi hypothetical protein 0.0005 0.0004 0.0037
Trichomonas vaginalis esterase, putative 0.0042 0.0161 1
Mycobacterium tuberculosis Conserved protein 0.0042 0.0161 0.0175
Mycobacterium ulcerans D-amino acid oxidase Aao 0.0198 0.0819 0.0758
Echinococcus granulosus neutral sphingomyelinase 0.0004 0.0001 0.0004
Brugia malayi beta-lactamase family protein 0.0042 0.0161 0.1411
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.013 0.1135
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0161 0.1965
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0161 0.0161
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0027 0.0255
Brugia malayi nuclear receptor NHR-67 0.0005 0.0004 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0087 0.5419
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.004 0.0151 0.0392
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Echinococcus multilocularis glycerol 3 phosphate dehydrogenase 0.0198 0.0819 0.2127
Schistosoma mansoni hypothetical protein 0.0035 0.013 0.0129
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Loa Loa (eye worm) tnks protein 0.0253 0.1051 0.1051
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0087
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0066 0.08
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0005 0.0006 0.0375
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0005 0.0004 0.0011
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0004 0.0001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Echinococcus multilocularis neutral sphingomyelinase 0.0004 0.0001 0.0001
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0161 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0161 0.0419
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0161 0.0175
Schistosoma mansoni poly [ADP-ribose] polymerase 0.004 0.0151 0.015
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.004 0.0151 0.1839
Trypanosoma brucei FAD dependent oxidoreductase, putative 0.0198 0.0819 1
Mycobacterium ulcerans lipase LipD 0.0042 0.0161 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0198 0.0819 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0027 0.0026
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0161 1
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0066 0.0577
Echinococcus multilocularis tankyrase 0.0277 0.1153 0.2996
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0027 0.0026
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0005 0.0004 0.0011
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0005 0.0004 0.0011
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0005 0.0004 0.0037
Trichomonas vaginalis 2-5A-dependent ribonuclease, putative 0.0004 0.0001 0.0091
Entamoeba histolytica hypothetical protein 0.004 0.0151 0.1839
Brugia malayi ecdysone receptor 0.0005 0.0004 0.0037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0207 0.0538
Trypanosoma brucei L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0198 0.0819 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0264 0.3226
Echinococcus multilocularis FAD dependent oxidoreductase domain containing protein 0.0198 0.0819 0.2127
Onchocerca volvulus 0.001 0.0027 0.0255
Trypanosoma brucei electron transfer flavoprotein-ubiquinone oxidoreductase, putative 0.0198 0.0819 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.0005 0.0004 0.0037
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0004 0.0001 0.0031
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0104 0.1266
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0161 0.0175
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0004 0.0037
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0005 0.0007 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0005 0.0004 0.0036
Brugia malayi coiled-coil like protein 1 0.0025 0.0087 0.0765
Plasmodium falciparum protein kinase, putative 0.0025 0.0087 0.1062
Echinococcus granulosus FAD dependent oxidoreductase domain containing protein 0.0198 0.0819 0.71
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.0445 0.389
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0053 0.0207 0.0207
Mycobacterium ulcerans D-amino acid oxidase Aao 0.2372 1 1
Mycobacterium ulcerans glycerol-3-phosphate dehydrogenase GlpD2 0.0198 0.0819 0.0758
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0198 0.0819 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0027 0.007
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0039 0.0149 0.1818
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0027 0.0235
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0066 0.08
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0264 0.3226
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Loa Loa (eye worm) RNA binding protein 0.0073 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.0075 0.0299 0.0298
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0916 0.3849 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0264 0.0264
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0293 0.0293
Schistosoma mansoni lar interacting protein (lip)-related protein 0.0025 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0161
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0004 0.0001 0.0004
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0198 0.0819 0.0818
Trichomonas vaginalis multiple ankyrin repeats single kh domain protein, putative 0.0004 0.0001 0.0091
Trichomonas vaginalis ankyrin, putative 0.0004 0.0001 0.0091
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0104 0.1266
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0207 0.0207
Brugia malayi cDNA sequence BC016226 0.0198 0.0819 0.7162
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0161
Leishmania major hypothetical protein, conserved 0.0198 0.0819 1
Loa Loa (eye worm) nuclear hormone receptor 0.0005 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0005 0.0007 0.0006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0027 0.0235
Trichomonas vaginalis protein phosphatase 1 regulatory subunit 12C, putative 0.0004 0.0001 0.0091
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0066 0.4091
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Trypanosoma cruzi palmitoyl acyltransferase 1, putative 0.0004 0.0001 0.0012
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0161 0.0175
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0161 0.0175
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0161 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0004 0.0001 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0104 0.1266
Brugia malayi Muscleblind-like protein 0.0169 0.0696 0.6088
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0027 0.0233
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0027 0.0233
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0004 0.0001 0.0031
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.013 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0027 0.0235
Brugia malayi hypothetical protein 0.0005 0.0004 0.0037
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0264 0.0687
Brugia malayi dimethylglycine dehydrogenase, mitochondrial precursor, putative 0.0198 0.0819 0.7162
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0027 0.007
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0027 0.0026
Trichomonas vaginalis unc-44 ankyrins, putative 0.0004 0.0001 0.0091
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0027 0.0233
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0027 0.0026
Plasmodium vivax FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0198 0.0819 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.013 0.1125
Schistosoma mansoni survival motor neuron protein 0.0049 0.0189 0.0188
Onchocerca volvulus Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial homolog 0.0198 0.0819 0.792
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0005 0.0004 0.0004
Mycobacterium tuberculosis Possible thiamine biosynthesis oxidoreductase ThiO 0.0198 0.0819 0.0893
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0161 0.1411
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0027 0.0026
Schistosoma mansoni hypothetical protein 0.0049 0.0189 0.0188
Brugia malayi Liprin-alpha 2 0.0025 0.0087 0.0765
Loa Loa (eye worm) hypothetical protein 0.0005 0.0007 0.0006
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.0445 0.0444
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.004 0.0151 0.015
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Plasmodium vivax tyrosine kinase-like protein, putative 0.0025 0.0087 0.1062
Brugia malayi ecdysteroid receptor 0.001 0.0027 0.0235
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0207 0.1796
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0161 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.013 0.1125
Loa Loa (eye worm) hypothetical protein 0.0169 0.0696 0.0696
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0066 0.0065
Leishmania major huntingtin interacting protein (HIP), putative 0.0004 0.0001 0.0012
Onchocerca volvulus 0.0005 0.0004 0.0036
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0004 0.0001 0.0091
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0027 0.0235
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0198 0.0819 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0161 0.0175
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.0989 0.8575
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0027 0.0235
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0005 0.0004 0.0011
Echinococcus multilocularis SAM domain containing protein 0.0025 0.0087 0.0227
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0027 0.007
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0264 0.2314
Brugia malayi beta-lactamase family protein 0.0042 0.0161 0.1411
Echinococcus multilocularis liprin alpha 2 0.0025 0.0087 0.0227
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0004 0.0004
Echinococcus granulosus glycerol 3 phosphate dehydrogenase 0.0198 0.0819 0.71
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0027 0.0026
Echinococcus granulosus Ankyrin 0.0004 0.0001 0.0013
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0004 0.0037
Brugia malayi pyruvate dehydrogenase phosphatase regulatory subunit precursor 0.0198 0.0819 0.7162
Schistosoma mansoni hypothetical protein 0.019 0.0788 0.0788
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0027 0.0235
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0207 0.0207
Mycobacterium tuberculosis Conserved protein 0.0042 0.0161 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Onchocerca volvulus Putative fad oxidoreductase 0.0198 0.0819 0.792
Loa Loa (eye worm) hypothetical protein 0.0238 0.0989 0.0989
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.