Detailed information for compound 1831078

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 487.572 | Formula: C23H29N5O5S
  • H donors: 0 H acceptors: 6 LogP: 3.37 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N1CCC(CC1)n1ncc2c1ncnc2Oc1ccc(cc1)S(=O)(=O)C)OCC(C)(C)C
  • InChi: 1S/C23H29N5O5S/c1-23(2,3)14-32-22(29)27-11-9-16(10-12-27)28-20-19(13-26-28)21(25-15-24-20)33-17-5-7-18(8-6-17)34(4,30)31/h5-8,13,15-16H,9-12,14H2,1-4H3
  • InChiKey: HBTDXOHROQCMQO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.019 0.0788 0.0788
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0161 0.1965
Echinococcus granulosus nuclear receptor nhr 48 0.0005 0.0004 0.0036
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0104 0.1266
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0293 0.2564
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.013 0.0337
Onchocerca volvulus Tankyrase homolog 0.0249 0.1034 1
Trypanosoma brucei palmitoyl acyltransferase 1, putative 0.0004 0.0001 0.0012
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Echinococcus granulosus poly ADP ribose polymerase 1 0.004 0.0151 0.1309
Echinococcus multilocularis liprin beta 1 0.0025 0.0087 0.0227
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0161
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0146 0.038
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Mycobacterium leprae Probable cholesterol oxidase precursor ChoD (cholesterol-O2 oxidoreductase) 0.0198 0.0819 0.0668
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0027 0.0233
Mycobacterium leprae Possible thiamine biosynthesis oxidoreductase ThiO 0.0198 0.0819 0.0668
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0004 0.0001 0.0004
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Echinococcus multilocularis sterile alpha and tir motif containing protein 0.0025 0.0087 0.0227
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0066 0.08
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0027 0.0233
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0161 0.1965
Schistosoma mansoni thyroid hormone receptor 0.001 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Brugia malayi hypothetical protein 0.0025 0.0087 0.0765
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0027 0.007
Leishmania major glycerol-3-phosphate dehydrogenase-like protein 0.0198 0.0819 1
Onchocerca volvulus 0.0042 0.0161 0.1557
Brugia malayi latrophilin 2 splice variant baaae 0.0075 0.0299 0.2615
Chlamydia trachomatis D-amino acid dehydrogenase 0.0198 0.0819 0.5
Brugia malayi hypothetical protein 0.0025 0.0087 0.0765
Schistosoma mansoni ankyrin 23/unc44 0.0004 0.0001 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0066 0.08
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0038 0.0098
Brugia malayi hypothetical protein 0.0039 0.0149 0.1306
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0027 0.0026
Brugia malayi beta-lactamase 0.0042 0.0161 0.1411
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Brugia malayi Patatin-like phospholipase family protein 0.0004 0.0001 0.0013
Mycobacterium ulcerans hypothetical protein 0.0042 0.0161 0.0096
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0149 0.0388
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0005 0.0007 0.0057
Echinococcus granulosus Sterile alpha motif SAM 0.0025 0.0087 0.0758
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Toxoplasma gondii hypothetical protein 0.0198 0.0819 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0161 0.0175
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0027 0.0026
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0161 1
Brugia malayi RNA binding protein 0.0073 0.0293 0.2564
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), mitochondrial 0.0198 0.0819 1
Onchocerca volvulus 0.0025 0.0087 0.0841
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0005 0.0007 0.0017
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0264 0.3226
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0161 0.0175
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0149 0.1295
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0004 0.0001 0.0091
Brugia malayi tailless protein 0.0005 0.0004 0.0037
Echinococcus multilocularis synaptojanin 1 0.0004 0.0001 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0161 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0151 0.015
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0066 0.0572
Onchocerca volvulus Dimethylglycine dehydrogenase, mitochondrial homolog 0.0198 0.0819 0.792
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0005 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0027 0.0235
Schistosoma mansoni hypothetical protein 0.0025 0.0087 0.0087
Brugia malayi Latrophilin receptor protein 2 0.0035 0.013 0.1135
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0198 0.0819 1
Trypanosoma brucei glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0198 0.0819 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0207 0.0207
Schistosoma mansoni hypothetical protein 0.0075 0.0299 0.0298
Onchocerca volvulus 0.0042 0.0161 0.1557
Brugia malayi nuclear receptor NHR-88 0.0005 0.0004 0.0037
Schistosoma mansoni zinc finger protein 0.0005 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0013 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0007 0.0058
Plasmodium falciparum FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0198 0.0819 1
Mycobacterium ulcerans beta-lactamase 0.0042 0.0161 0.0096
Brugia malayi nuclear receptor RXR 0.0005 0.0007 0.0058
Echinococcus granulosus liprin alpha 2 0.0025 0.0087 0.0758
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0027 0.0235
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0002 0.0102
Trypanosoma cruzi palmitoyl acyltransferase 1, putative 0.0004 0.0001 0.0012
Brugia malayi orphan nuclear receptor NR2E1 0.0005 0.0004 0.0037
Loa Loa (eye worm) glycerol-3-phosphate dehydrogenase 0.0198 0.0819 0.0818
Schistosoma mansoni nuclear receptor 0.0005 0.0004 0.0004
Loa Loa (eye worm) nuclear receptor NHR-67 0.0005 0.0004 0.0004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0027 0.0233
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0149 0.0149
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0004 0.0001 0.0031
Echinococcus granulosus sterile alpha and tir motif containing protein 0.0025 0.0087 0.0758
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.0989 0.2569
Loa Loa (eye worm) hypothetical protein 0.0035 0.013 0.0129
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0005 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0161
Entamoeba histolytica hypothetical protein 0.004 0.0151 0.1839
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0004 0.0001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Echinococcus granulosus stromal interaction molecule 1 0.0025 0.0087 0.0758
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0066 0.08
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.013 0.0337
Entamoeba histolytica hypothetical protein 0.0039 0.0149 0.1818
Schistosoma mansoni NAD dehydrogenase 0.0198 0.0819 0.0818
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0004 0.0001 0.0004
Schistosoma mansoni d-amino acid oxidase 0.2372 1 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0066 0.08
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0104 0.1266
Loa Loa (eye worm) hypothetical protein 0.0198 0.0819 0.0818
Loa Loa (eye worm) DR-78 0.0005 0.0004 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0027 0.0233
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0104 0.1266
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0087
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Trichomonas vaginalis Phospholipase C precursor, putative 0.0004 0.0001 0.0031
Echinococcus multilocularis GPCR, family 2 0.0035 0.013 0.0337
Brugia malayi nuclear receptor RXR 0.0005 0.0004 0.0037
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0207 0.1796
Trichomonas vaginalis ion channel nompc, putative 0.0004 0.0001 0.0091
Echinococcus granulosus geminin 0.019 0.0788 0.6833
Loa Loa (eye worm) hypothetical protein 0.0169 0.0696 0.0696
Loa Loa (eye worm) hypothetical protein 0.0028 0.0104 0.0104
Brugia malayi hypothetical protein 0.0005 0.0007 0.0058
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0264 0.2293
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0027 0.0026
Schistosoma mansoni glycerol-3-phosphate dehydrogenase 0.0198 0.0819 0.0818
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.0007 0.0006
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0146 0.1269
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0027 0.0235
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0293 0.0293
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0005 0.0004 0.0011
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.004 0.0151 0.1839
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Schistosoma mansoni sarm1 0.0025 0.0087 0.0087
Schistosoma mansoni tankyrase 0.0277 0.1155 0.1154
Brugia malayi nuclear receptor NHR-88 0.001 0.0027 0.0235
Echinococcus multilocularis deoxyribonuclease 1 2 0.0004 0.0001 0.0001
Toxoplasma gondii ABC1 family protein 0.0042 0.0161 0.1965
Brugia malayi WGR domain containing protein 0.004 0.0151 0.132
Echinococcus granulosus liprin beta 1 0.0025 0.0087 0.0758
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Schistosoma mansoni poly [ADP-ribose] polymerase 0.004 0.0151 0.015
Echinococcus granulosus FTZ F1 alpha 0.001 0.0027 0.0233
Brugia malayi nuclear hormone receptor family member odr-7 0.0005 0.0004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Echinococcus multilocularis muscleblind protein 0.0169 0.0696 0.1808
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0161
Schistosoma mansoni ap endonuclease 0.0019 0.0066 0.0065
Schistosoma mansoni hypothetical protein 0.0025 0.0087 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0293 0.0293
Trypanosoma cruzi FAD dependent oxidoreductase, putative 0.0198 0.0819 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0027 0.0235
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0264 0.3226
Onchocerca volvulus 0.0005 0.0004 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0087 0.5419
Brugia malayi TAR-binding protein 0.0073 0.0293 0.2564
Entamoeba histolytica anaerobic glycerol-3-phosphate dehydrogenase subunit A, putative 0.0198 0.0819 1
Schistosoma mansoni hypothetical protein 0.0039 0.0149 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Toxoplasma gondii exonuclease III APE 0.0019 0.0066 0.08
Echinococcus multilocularis poly (ADP ribose) polymerase 0.004 0.0151 0.0392
Brugia malayi Neurabin protein 1 0.0025 0.0087 0.0765
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0005 0.0004 0.0004
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0027 0.0255
Echinococcus multilocularis muscleblind protein 1 0.0169 0.0696 0.1808
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0161 0.1965
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0027 0.0026
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0027 0.0235
Entamoeba histolytica zinc finger protein, putative 0.004 0.0151 0.1839
Echinococcus granulosus GPCR family 2 0.0035 0.013 0.1125
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Leishmania major hypothetical protein, conserved 0.0198 0.0819 1
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 20 0.0198 0.0819 1
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0025 0.0087 0.1062
Echinococcus granulosus Nuclear hormone receptor HR96 0.0005 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0161
Echinococcus granulosus Nuclear hormone receptor HR96 0.0005 0.0004 0.0036
Onchocerca volvulus 0.0049 0.0189 0.1824
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0027 0.007
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0161 0.0096
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.004 0.0151 0.1839
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0087 0.5419
Brugia malayi sterile alpha and TIR motif containing protein 1 isoform a 0.0025 0.0087 0.0765
Schistosoma mansoni hypothetical protein 0.0035 0.013 0.0129
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0027 0.007
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0198 0.0819 1
Mycobacterium tuberculosis Probable D-amino acid oxidase Aao 0.2175 0.9165 1
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0198 0.0819 1
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0027 0.0255
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0066 0.5
Brugia malayi steroid hormone receptor 0.001 0.0027 0.0235
Echinococcus granulosus tar DNA binding protein 0.0073 0.0293 0.2541
Schistosoma mansoni hypothetical protein 0.0035 0.013 0.0129
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0066 0.0071
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0004 0.0001 0.0031
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0293 0.0293
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0007 0.0058
Schistosoma mansoni fad oxidoreductase 0.0198 0.0819 0.0818
Brugia malayi hypothetical protein 0.0238 0.0989 0.865
Schistosoma mansoni hypothetical protein 0.0035 0.013 0.0129
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Echinococcus granulosus tankyrase 0.0277 0.1153 1
Onchocerca volvulus 0.0042 0.0161 0.1557
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0293 0.0761
Loa Loa (eye worm) hypothetical protein 0.0198 0.0819 0.0818
Brugia malayi Tnks protein 0.0275 0.1143 1
Echinococcus granulosus synaptojanin 1 0.0004 0.0001 0.0004
Giardia lamblia Kinase, NEK 0.0004 0.0001 0.0012
Loa Loa (eye worm) beta-lactamase 0.0042 0.0161 0.0161
Schistosoma mansoni hypothetical protein 0.0025 0.0087 0.0087
Brugia malayi nuclear hormone receptor 0.001 0.0027 0.0235
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0027 0.007
Mycobacterium ulcerans thiamine biosynthesis oxidoreductase ThiO 0.0198 0.0819 0.0758
Leishmania major hypothetical protein, conserved 0.0028 0.0104 0.1266
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0264 0.0264
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0087
Trypanosoma brucei poly(adp-ribose) polymerase 0.004 0.0151 0.1839
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0053 0.0207 0.1812
Schistosoma mansoni ap endonuclease 0.0019 0.0066 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0027 0.0026
Schistosoma mansoni fad oxidoreductase 0.0198 0.0819 0.0818
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0207 0.0538
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0264 0.3226
Loa Loa (eye worm) hypothetical protein 0.0005 0.0007 0.0006
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.0445 0.389
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0293 0.0293
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0038 0.0328
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0027 0.007
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0005 0.0004 0.0262
Plasmodium falciparum tyrosine kinase-like protein 0.0025 0.0087 0.1062
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0027 0.007
Brugia malayi nuclear hormone receptor 0.0005 0.0004 0.0037
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0004 0.0001 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0027 0.0235
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0005 0.0004 0.0004
Echinococcus multilocularis geminin 0.019 0.0788 0.2047
Echinococcus multilocularis nuclear receptor nhr 48 0.0005 0.0004 0.0011
Trichomonas vaginalis ankyrin, putative 0.0004 0.0002 0.0102
Onchocerca volvulus 0.0025 0.0087 0.0841
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0027 0.0026
Echinococcus granulosus muscleblind protein 0.0169 0.0696 0.6035
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0027 0.0233
Loa Loa (eye worm) hypothetical protein 0.0209 0.0868 0.0868
Trichomonas vaginalis c2h2 zinc finger protein, putative 0.0025 0.0087 0.5419
Brugia malayi hypothetical protein 0.0005 0.0007 0.0058
Loa Loa (eye worm) hypothetical protein 0.0109 0.0445 0.0444
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0005 0.0004 0.0036
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0004 0.0001 0.0001
Brugia malayi conserved hypotetical protein 0.0005 0.0004 0.0037
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Schistosoma mansoni thyroid hormone receptor 0.001 0.0027 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0027 0.0235
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0104 0.1266
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0161 0.0175
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0005 0.0007 0.0006
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0004 0.0037
Plasmodium falciparum protein kinase, putative 0.0025 0.0087 0.1062
Echinococcus granulosus FAD dependent oxidoreductase domain containing protein 0.0198 0.0819 0.71
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0005 0.0004 0.0036
Brugia malayi coiled-coil like protein 1 0.0025 0.0087 0.0765
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.0445 0.389
Mycobacterium ulcerans D-amino acid oxidase Aao 0.2372 1 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0053 0.0207 0.0207
Mycobacterium ulcerans glycerol-3-phosphate dehydrogenase GlpD2 0.0198 0.0819 0.0758
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0198 0.0819 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0027 0.0235
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0066 0.08
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0027 0.007
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0039 0.0149 0.1818
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0264 0.3226
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0916 0.3849 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0299 0.0298
Loa Loa (eye worm) RNA binding protein 0.0073 0.0293 0.0293
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0264 0.0264
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0293 0.0293
Schistosoma mansoni lar interacting protein (lip)-related protein 0.0025 0.0087 0.0087
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0004 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0161
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0027 0.0026
Trichomonas vaginalis ankyrin, putative 0.0004 0.0001 0.0091
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0104 0.1266
Trichomonas vaginalis multiple ankyrin repeats single kh domain protein, putative 0.0004 0.0001 0.0091
Loa Loa (eye worm) hypothetical protein 0.0198 0.0819 0.0818
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0207 0.0207
Leishmania major hypothetical protein, conserved 0.0198 0.0819 1
Brugia malayi cDNA sequence BC016226 0.0198 0.0819 0.7162
Loa Loa (eye worm) hypothetical protein 0.0042 0.0161 0.0161
Loa Loa (eye worm) nuclear hormone receptor 0.0005 0.0004 0.0004
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0066 0.4091
Trichomonas vaginalis protein phosphatase 1 regulatory subunit 12C, putative 0.0004 0.0001 0.0091
Loa Loa (eye worm) hypothetical protein 0.0005 0.0007 0.0006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0027 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Trypanosoma cruzi palmitoyl acyltransferase 1, putative 0.0004 0.0001 0.0012
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0161 0.0175
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0161 0.0175
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0161 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0004 0.0001 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0104 0.1266
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0027 0.0233
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0027 0.0233
Brugia malayi Muscleblind-like protein 0.0169 0.0696 0.6088
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.013 0.0129
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0004 0.0001 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0027 0.0235
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0264 0.0687
Brugia malayi hypothetical protein 0.0005 0.0004 0.0037
Trichomonas vaginalis unc-44 ankyrins, putative 0.0004 0.0001 0.0091
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0027 0.0026
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0027 0.007
Brugia malayi dimethylglycine dehydrogenase, mitochondrial precursor, putative 0.0198 0.0819 0.7162
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0027 0.0233
Plasmodium vivax FAD-dependent glycerol-3-phosphate dehydrogenase, putative 0.0198 0.0819 1
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0027 0.0026
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.013 0.1125
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0005 0.0004 0.0004
Onchocerca volvulus Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial homolog 0.0198 0.0819 0.792
Schistosoma mansoni survival motor neuron protein 0.0049 0.0189 0.0188
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Mycobacterium tuberculosis Possible thiamine biosynthesis oxidoreductase ThiO 0.0198 0.0819 0.0893
Brugia malayi Liprin-alpha 2 0.0025 0.0087 0.0765
Loa Loa (eye worm) hypothetical protein 0.0005 0.0007 0.0006
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0161 0.1411
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0027 0.0026
Schistosoma mansoni hypothetical protein 0.0049 0.0189 0.0188
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.004 0.0151 0.015
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0293 0.0293
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.0445 0.0444
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0026
Plasmodium vivax tyrosine kinase-like protein, putative 0.0025 0.0087 0.1062
Brugia malayi ecdysteroid receptor 0.001 0.0027 0.0235
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0207 0.1796
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0161 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.013 0.1125
Loa Loa (eye worm) hypothetical protein 0.0169 0.0696 0.0696
Leishmania major huntingtin interacting protein (HIP), putative 0.0004 0.0001 0.0012
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0066 0.0065
Onchocerca volvulus 0.0005 0.0004 0.0036
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0161 0.0175
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase (FAD-dependent), putative 0.0198 0.0819 1
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0027 0.0235
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0004 0.0001 0.0091
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0027 0.007
Echinococcus multilocularis SAM domain containing protein 0.0025 0.0087 0.0227
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.0989 0.8575
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0005 0.0004 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0027 0.0235
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0264 0.2314
Brugia malayi beta-lactamase family protein 0.0042 0.0161 0.1411
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0004 0.0004
Echinococcus granulosus glycerol 3 phosphate dehydrogenase 0.0198 0.0819 0.71
Echinococcus multilocularis liprin alpha 2 0.0025 0.0087 0.0227
Echinococcus granulosus Ankyrin 0.0004 0.0001 0.0013
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0027 0.0026
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0004 0.0037
Brugia malayi pyruvate dehydrogenase phosphatase regulatory subunit precursor 0.0198 0.0819 0.7162
Schistosoma mansoni hypothetical protein 0.019 0.0788 0.0788
Onchocerca volvulus Putative fad oxidoreductase 0.0198 0.0819 0.792
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0207 0.0207
Mycobacterium tuberculosis Conserved protein 0.0042 0.0161 0.0175
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0027 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Loa Loa (eye worm) hypothetical protein 0.0238 0.0989 0.0989
Entamoeba histolytica hypothetical protein 0.004 0.0151 0.1839
Entamoeba histolytica hypothetical protein 0.004 0.0151 0.1839
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0004 0.0001 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0027 0.0235
Mycobacterium tuberculosis Conserved protein 0.0042 0.0161 0.0175
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.004 0.0151 0.0392
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Entamoeba histolytica hypothetical protein 0.0039 0.0149 0.1818
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Entamoeba histolytica hypothetical protein 0.0039 0.0149 0.1818
Echinococcus multilocularis traf and tnf receptor associated protein 0.0004 0.0001 0.0001
Loa Loa (eye worm) toll and interleukin 1 receptor domain-containing protein isoform f 0.0025 0.0087 0.0087
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0004 0.0001 0.0091
Schistosoma mansoni lip-related protein (liprin) alpha 0.0025 0.0087 0.0087
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0004 0.0001 0.0001
Echinococcus multilocularis stromal interaction molecule 1 0.0025 0.0087 0.0227
Leishmania major hypothetical protein, conserved 0.0042 0.0161 0.1965
Toxoplasma gondii FAD-dependent glycerol-3-phosphate dehydrogenase 0.0198 0.0819 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0007 0.0006
Brugia malayi CCR4 0.0004 0.0001 0.0004
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0027 0.0026
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0066 0.0171
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0104 0.1266
Schistosoma mansoni nuclear receptor 0.0005 0.0004 0.0004
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0066 0.08
Echinococcus granulosus traf and tnf receptor associated protein 0.0004 0.0001 0.0004
Mycobacterium ulcerans glycerol-3-phosphate dehydrogenase 0.0198 0.0819 0.0758
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Schistosoma mansoni nuclear hormone receptor 0.001 0.0027 0.0026
Trypanosoma cruzi glycerol-3-phosphate dehydrogenase, putative 0.0198 0.0819 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0005 0.0004 0.0036
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0161 0.0161
Giardia lamblia Kinase, NEK 0.0004 0.0001 0.0012
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0066 0.4091
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0189 0.1653
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0005 0.0004 0.0273
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0087 0.5419
Brugia malayi hypothetical protein 0.0018 0.0062 0.0538
Echinococcus granulosus poly adp ribose polymerase 2 0.004 0.0151 0.1309
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0004 0.0001 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0027 0.0235
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0004 0.0004
Brugia malayi hypothetical protein 0.0028 0.0104 0.091
Echinococcus granulosus thyroid hormone receptor alpha 0.0005 0.0004 0.0036
Schistosoma mansoni coup transcription factor 0.001 0.0027 0.0026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0161 0.0161
Echinococcus multilocularis Ankyrin 0.0004 0.0002 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0027 0.0026
Schistosoma mansoni ATP:guanidino kinase (Smc74) 0.0198 0.0819 0.0818
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0066 0.08
Loa Loa (eye worm) hypothetical protein 0.0004 0.0002 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0027 0.0235
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0004 0.0001 0.0091
Schistosoma mansoni nuclear receptor nhr-48 0.0005 0.0004 0.0004
Trichomonas vaginalis unc-44 ankyrins, putative 0.0004 0.0001 0.0091
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0161 0.1399
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0004 0.0001 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0004 0.0001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0005 0.0007 0.0006
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0268 0.1117 0.1219
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.004 0.0151 0.1839
Schistosoma mansoni hypothetical protein 0.0025 0.0087 0.0087
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0066 1
Mycobacterium leprae PROBABLE D-AMINO ACID OXIDASE AAO 0.2372 1 1
Brugia malayi WGR domain containing protein 0.004 0.0151 0.132
Echinococcus granulosus SAM domain containing protein 0.0025 0.0087 0.0758
Brugia malayi RE18450p 0.0198 0.0819 0.7162
Mycobacterium ulcerans D-amino acid oxidase Aao 0.0198 0.0819 0.0758
Mycobacterium tuberculosis Conserved protein 0.0042 0.0161 0.0175
Echinococcus granulosus neutral sphingomyelinase 0.0004 0.0001 0.0004
Trichomonas vaginalis esterase, putative 0.0042 0.0161 1
Brugia malayi hypothetical protein 0.0005 0.0004 0.0037
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.013 0.1135
Brugia malayi beta-lactamase family protein 0.0042 0.0161 0.1411
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0161 0.1965
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0161 0.0161
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0027 0.0255
Brugia malayi nuclear receptor NHR-67 0.0005 0.0004 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0087 0.5419
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0004 0.0001 0.0004
Echinococcus multilocularis glycerol 3 phosphate dehydrogenase 0.0198 0.0819 0.2127
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.004 0.0151 0.0392
Schistosoma mansoni hypothetical protein 0.0035 0.013 0.0129
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Loa Loa (eye worm) tnks protein 0.0253 0.1051 0.1051
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0066 0.08
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0087
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0005 0.0006 0.0375
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0004 0.0001 0.0031
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0005 0.0004 0.0011
Echinococcus multilocularis neutral sphingomyelinase 0.0004 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0005 0.0004 0.0004
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0161 1
Schistosoma mansoni poly [ADP-ribose] polymerase 0.004 0.0151 0.015
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.004 0.0151 0.1839
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0161 0.0175
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0161 0.0419
Trypanosoma brucei FAD dependent oxidoreductase, putative 0.0198 0.0819 1
Mycobacterium ulcerans lipase LipD 0.0042 0.0161 0.0096
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0027 0.0026
Trypanosoma cruzi L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0198 0.0819 1
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0151 0.9357
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0066 0.0577
Echinococcus multilocularis tankyrase 0.0277 0.1153 0.2996
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0161 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0027 0.0026
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0005 0.0004 0.0011
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0005 0.0004 0.0011
Trichomonas vaginalis 2-5A-dependent ribonuclease, putative 0.0004 0.0001 0.0091
Brugia malayi ecdysone receptor 0.0005 0.0004 0.0037
Entamoeba histolytica hypothetical protein 0.004 0.0151 0.1839
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0005 0.0004 0.0037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0207 0.0538
Trypanosoma brucei L-2-hydroxyglutarate dehydrogenase, mitochondrial, putative 0.0198 0.0819 1
Echinococcus multilocularis FAD dependent oxidoreductase domain containing protein 0.0198 0.0819 0.2127
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0264 0.3226
Brugia malayi nuclear hormone receptor family member nhr-6 0.0005 0.0004 0.0037
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0004 0.0001 0.0031
Onchocerca volvulus 0.001 0.0027 0.0255
Trypanosoma brucei electron transfer flavoprotein-ubiquinone oxidoreductase, putative 0.0198 0.0819 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.