Detailed information for compound 1833027

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 416.423 | Formula: C25H20O6
  • H donors: 1 H acceptors: 3 LogP: 4.22 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)c1c(oc2c(c1=O)ccc(c2CC(=O)O)OC)c1ccccc1
  • InChi: 1S/C25H20O6/c1-29-17-10-8-15(9-11-17)22-23(28)18-12-13-20(30-2)19(14-21(26)27)25(18)31-24(22)16-6-4-3-5-7-16/h3-13H,14H2,1-2H3,(H,26,27)
  • InChiKey: YJOIVOAKUZWFJW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis slit 1 protein 0.0055 0.0413 0.0413
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Echinococcus multilocularis thyroid hormone receptor alpha 0.0023 0.0074 0.0074
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Plasmodium falciparum protein kinase, putative 0.0478 0.4996 1
Trypanosoma brucei protein phosphatase 1, regulatory subunit, putative 0.0055 0.0413 0.0729
Echinococcus multilocularis tyrosine protein kinase Abl 0.0478 0.4996 0.4996
Leishmania major hypothetical protein, conserved 0.0055 0.0413 0.0729
Toxoplasma gondii NAC domain-containing protein 0.008 0.0692 0.1295
Loa Loa (eye worm) TK/ALK protein kinase 0.0478 0.4996 1
Entamoeba histolytica hypothetical protein 0.0533 0.5586 1
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0478 0.4996 1
Brugia malayi CCR4 0.0059 0.0459 0.0891
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Entamoeba histolytica hypothetical protein 0.0533 0.5586 1
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0074 0.0074
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0074 0.0074
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0478 0.4996 0.4996
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0478 0.4996 0.4996
Trypanosoma cruzi leucine-rich repeat protein, putative 0.0055 0.0413 0.0729
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Plasmodium vivax protein phosphatases PP1 regulatory subunit sds22, putative 0.0055 0.0413 0.0729
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Entamoeba histolytica serine/threonine kinase, putative 0.0478 0.4996 0.8934
Onchocerca volvulus 0.0478 0.4996 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0074 0.0074
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0478 0.4996 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0478 0.4996 0.4996
Onchocerca volvulus 0.0055 0.0413 0.0688
Echinococcus granulosus tyrosine protein kinase 0.0478 0.4996 0.4996
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Onchocerca volvulus 0.0055 0.0413 0.0688
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0413 0.0729
Entamoeba histolytica villidin, putative 0.0055 0.0413 0.0651
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0055 0.0413 0.0798
Echinococcus multilocularis protein flightless 1 0.0055 0.0413 0.0413
Trypanosoma cruzi protein phosphatase 1, regulatory subunit, putative 0.0055 0.0413 0.0729
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Brugia malayi RNA binding protein 0.0074 0.0624 0.1223
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Echinococcus multilocularis protein tyrosine kinase 0.0478 0.4996 0.4996
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0074 0.0074
Schistosoma mansoni hypothetical protein 0.0055 0.0413 0.0413
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0074 0.0074
Toxoplasma gondii leucine-rich repeat protein LRR1 0.0055 0.0413 0.0729
Loa Loa (eye worm) TK/EPH protein kinase 0.0478 0.4996 1
Leishmania major hypothetical protein, conserved 0.0478 0.4996 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0074 0.0118
Brugia malayi EGF-like domain containing protein 0.0055 0.0413 0.0798
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0478 0.4996 1
Schistosoma mansoni hypothetical protein 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0478 0.4996 0.4996
Schistosoma mansoni hypothetical protein 0.0018 0.0015 0.0015
Trichomonas vaginalis protein phosphatase 2C, putative 0.0055 0.0413 0.0729
Plasmodium falciparum basic transcription factor 3b, putative 0.008 0.0692 0.1295
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0083 0.0718 0.0718
Echinococcus multilocularis tyrosine protein kinase Blk 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) TK protein kinase 0.0478 0.4996 1
Entamoeba histolytica hypothetical protein 0.008 0.0692 0.1157
Brugia malayi C-terminal src kinase protein 1 0.0478 0.4996 1
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0478 0.4996 0.4996
Echinococcus granulosus leucine rich repeat protein 1 0.0055 0.0413 0.0413
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0055 0.0413 0.0651
Echinococcus granulosus fibroblast growth factor receptor 4 0.0478 0.4996 0.4996
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0074 0.0074
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0478 0.4996 0.8934
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Echinococcus granulosus tyrosine protein kinase Lyn 0.0478 0.4996 0.4996
Echinococcus multilocularis leucine rich repeat containing protein 70 0.0055 0.0413 0.0413
Echinococcus granulosus c src tyrosine kinase 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus multilocularis ras suppressor protein 1 0.0055 0.0413 0.0413
Schistosoma mansoni peroxidasin 0.0055 0.0413 0.0413
Echinococcus multilocularis tyrosine protein kinase Srms 0.0478 0.4996 0.4996
Echinococcus multilocularis integrin linked protein kinase 0.0478 0.4996 0.4996
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Trichomonas vaginalis leucine-rich transmembrane protein, putative 0.0055 0.0413 0.0729
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0478 0.4996 0.4996
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0624 0.0624
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0478 0.4996 0.4996
Echinococcus multilocularis c src tyrosine kinase 0.0478 0.4996 0.4996
Onchocerca volvulus 0.0055 0.0413 0.0688
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0015 0.0015
Entamoeba histolytica tyrosin kinase, putative 0.0478 0.4996 0.8934
Giardia lamblia Kinase, NEK 0.0478 0.4996 1
Brugia malayi nuclear hormone receptor 0.0023 0.0074 0.0118
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Brugia malayi ecdysteroid receptor 0.0023 0.0074 0.0118
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Plasmodium vivax tyrosine kinase-like protein, putative 0.0478 0.4996 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0478 0.4996 0.4996
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Trypanosoma brucei Flagellum attachment zone protein 20 0.0478 0.4996 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0478 0.4996 0.4996
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Echinococcus granulosus tyrosine protein kinase csk 0.0478 0.4996 0.4996
Schistosoma mansoni protein kinase 0.0478 0.4996 0.4996
Trypanosoma brucei Basal body protein 0.0055 0.0413 0.0729
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Loa Loa (eye worm) TK/DDR protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0478 0.4996 0.4996
Echinococcus granulosus leucine rich repeat containing protein 24 0.0055 0.0413 0.0413
Onchocerca volvulus 0.0055 0.0413 0.0688
Entamoeba histolytica tyrosin kinase, putative 0.0478 0.4996 0.8934
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Trichomonas vaginalis CAMK family protein kinase 0.0478 0.4996 1
Echinococcus granulosus tyrosine kinase 0.0478 0.4996 0.4996
Trichomonas vaginalis protein phosphatase 2C, putative 0.0055 0.0413 0.0729
Trypanosoma brucei phosphatase, putative 0.0055 0.0413 0.0729
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0074 0.0118
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Echinococcus multilocularis epidermal growth factor receptor 0.0478 0.4996 0.4996
Echinococcus granulosus slit 1 protein 0.0055 0.0413 0.0413
Echinococcus granulosus receptor type guanylyl cyclase 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK protein kinase 0.0478 0.4996 1
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0478 0.4996 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0015 0.0015
Loa Loa (eye worm) sur-8-PB 0.0055 0.0413 0.0798
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0074 0.0118
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Echinococcus multilocularis tumor protein p63 0.0395 0.41 0.41
Trichomonas vaginalis leucine-rich transmembrane protein, putative 0.0055 0.0413 0.0729
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Echinococcus multilocularis leucine rich repeat containing protein 57 0.0055 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0023 0.0074 0.0118
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0055 0.0413 0.0651
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0059 0.0459 0.0823
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0478 0.4996 1
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0478 0.4996 0.4996
Entamoeba histolytica serine/threonine kinase, putative 0.0478 0.4996 0.8934
Trypanosoma cruzi leucine-rich repeat protein, putative 0.0055 0.0413 0.0729
Loa Loa (eye worm) protein kinase domain-containing protein 0.0478 0.4996 1
Onchocerca volvulus 0.0478 0.4996 1
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Loa Loa (eye worm) TK protein kinase 0.0478 0.4996 1
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Entamoeba histolytica DnaJ family protein 0.0055 0.0413 0.0651
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0478 0.4996 0.4996
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0478 0.4996 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0478 0.4996 1
Brugia malayi ephrin receptor 1 precursor 0.0478 0.4996 1
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0413 0.0729
Trypanosoma cruzi protein kinase, putative 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0052 0.5
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Trypanosoma cruzi leucine-rich repeat protein, putative 0.0055 0.0413 0.0729
Onchocerca volvulus 0.0478 0.4996 1
Trypanosoma cruzi kinatase, putative 0.0055 0.0413 0.0729
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0478 0.4996 1
Trypanosoma cruzi transcription factor btf3, putative 0.008 0.0692 0.1295
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0478 0.4996 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Schistosoma mansoni ras suppressor protein 1 rsu1 0.0055 0.0413 0.0413
Plasmodium vivax basic transcription factor 3b, putative 0.008 0.0692 0.1295
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Echinococcus multilocularis leucine rich repeat neuronal protein leucine rich repeat containing protein 0.0055 0.0413 0.0413
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Schistosoma mansoni protein kinase 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0055 0.0413 0.0798
Echinococcus multilocularis peroxidasin 0.0055 0.0413 0.0413
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) TK/CSK protein kinase 0.0478 0.4996 1
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Schistosoma mansoni slit 0.0055 0.0413 0.0413
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0478 0.4996 0.4996
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Schistosoma mansoni serine/threonine protein kinase 0.0478 0.4996 0.4996
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0074 0.0074
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Entamoeba histolytica hypothetical protein 0.0083 0.0718 0.1202
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0074 0.0074
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0074 0.0074
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0478 0.4996 0.8934
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0055 0.0413 0.0729
Trichomonas vaginalis podocan, putative 0.0055 0.0413 0.0729
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Brugia malayi Immunoglobulin I-set domain containing protein 0.0478 0.4996 1
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Onchocerca volvulus 0.0478 0.4996 1
Brugia malayi steroid hormone receptor 0.0023 0.0074 0.0118
Brugia malayi protein-tyrosine kinase 0.0478 0.4996 1
Loa Loa (eye worm) TK/ABL protein kinase 0.0478 0.4996 1
Plasmodium falciparum tyrosine kinase-like protein 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Schistosoma mansoni ephrin receptor 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0023 0.0074 0.0074
Echinococcus granulosus GPCR family 2 0.0018 0.0015 0.0015
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Echinococcus multilocularis protein KINase family member (kin 25) 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0074 0.0118
Echinococcus granulosus tyrosine protein kinase Srms 0.0478 0.4996 0.4996
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0413 0.0729
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Entamoeba histolytica hypothetical protein 0.0083 0.0718 0.1202
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Echinococcus multilocularis tyrosine kinase 0.0478 0.4996 0.4996
Leishmania major protein kinase, putative 0.0478 0.4996 1
Echinococcus granulosus leucine rich repeat and coiled coil 0.0055 0.0413 0.0413
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Giardia lamblia Hypothetical protein 0.0055 0.0413 0.0729
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0074 0.0118
Echinococcus granulosus tyrosine protein kinase shark 0.0478 0.4996 0.4996
Echinococcus granulosus Leucine rich repeat typical subtype 0.0055 0.0413 0.0413
Onchocerca volvulus 0.0478 0.4996 1
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0074 0.0118
Echinococcus granulosus tar DNA binding protein 0.0074 0.0624 0.0624
Plasmodium falciparum leucine-rich repeat protein 0.0055 0.0413 0.0729
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK/EGFR protein kinase 0.0478 0.4996 1
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Echinococcus granulosus leucine rich repeat containing protein 40 0.0055 0.0413 0.0413
Schistosoma mansoni coup transcription factor 0.0023 0.0074 0.0074
Schistosoma mansoni hypothetical protein 0.0055 0.0413 0.0413
Schistosoma mansoni hypothetical protein 0.0083 0.0718 0.0718
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus multilocularis heat shock protein 70 0.0478 0.4996 0.4996
Entamoeba histolytica cysteine surface protein, putative 0.0478 0.4996 0.8934
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) Ras-binding protein SUR-8 0.0055 0.0413 0.0798
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0055 0.0413 0.0651
Schistosoma mansoni shoc2 0.0055 0.0413 0.0413
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0478 0.4996 0.4996
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0055 0.0413 0.0651
Brugia malayi Protein kinase domain containing protein 0.0055 0.0413 0.0798
Trichomonas vaginalis leucine-rich transmembrane proteins, putative 0.0055 0.0413 0.0729
Entamoeba histolytica protein kinase, putative 0.0533 0.5586 1
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Toxoplasma gondii protein kinase 0.0478 0.4996 1
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.0055 0.0413 0.0729
Entamoeba histolytica leucine rich repeat and phosphatase domain containing protein 0.0055 0.0413 0.0651
Plasmodium falciparum leucine-rich repeat protein 0.0055 0.0413 0.0729
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Entamoeba histolytica serine/threonine kinase, putative 0.0478 0.4996 0.8934
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0074 0.0624 0.1223
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0478 0.4996 0.4996
Echinococcus granulosus tyrosine protein kinase Src42A 0.0478 0.4996 0.4996
Trichomonas vaginalis leucine-rich repeat-containing protein, putative 0.0055 0.0413 0.0729
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0478 0.4996 0.4996
Trichomonas vaginalis chaoptin, putative 0.0055 0.0413 0.0729
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0478 0.4996 0.4996
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Echinococcus granulosus kinase suppressor of Ras 1 0.0478 0.4996 0.4996
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus multilocularis FL cytokine receptor 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Onchocerca volvulus 0.0055 0.0413 0.0688
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0478 0.4996 0.4996
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0478 0.4996 1
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0074 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Echinococcus multilocularis leucine rich repeat containing protein 15 0.0055 0.0413 0.0413
Echinococcus multilocularis leucine rich repeat protein SHOC 2 0.0055 0.0413 0.0413
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Entamoeba histolytica hypothetical protein 0.0478 0.4996 0.8934
Trichomonas vaginalis leucine-rich transmembrane protein, putative 0.0055 0.0413 0.0729
Loa Loa (eye worm) TK/FAK protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0059 0.0459 0.0891
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0432 0.0836
Echinococcus multilocularis cell polarity protein leucine rich repeat 0.0055 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Trypanosoma cruzi Outer row dynein-assembly protein 7 0.0055 0.0413 0.0729
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0478 0.4996 0.4996
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Onchocerca volvulus 0.0066 0.0537 0.0941
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0432 0.0836
Schistosoma mansoni ap endonuclease 0.0021 0.0052 0.0052
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0478 0.4996 0.4996
Echinococcus granulosus cpg binding protein 0.007 0.0578 0.0578
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Brugia malayi TAR-binding protein 0.0074 0.0624 0.1223
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Onchocerca volvulus 0.0478 0.4996 1
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Echinococcus granulosus leucine rich repeat protein soc 2 0.0055 0.0413 0.0413
Loa Loa (eye worm) CXXC zinc finger family protein 0.0066 0.0537 0.1048
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0478 0.4996 1
Trypanosoma cruzi transcription factor btf3, putative 0.008 0.0692 0.1295
Schistosoma mansoni protein kinase 0.0478 0.4996 0.4996
Leishmania major leucine-rich repeat protein, putative 0.0055 0.0413 0.0729
Schistosoma mansoni hypothetical protein 0.0055 0.0413 0.0413
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0478 0.4996 1
Toxoplasma gondii leucine rich repeat-containing protein 0.0055 0.0413 0.0729
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Echinococcus granulosus ephrin type A receptor 4 A 0.0478 0.4996 0.4996
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Brugia malayi hypothetical protein 0.0083 0.0718 0.141
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.0055 0.0413 0.0729
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0478 0.4996 0.4996
Trypanosoma brucei hypothetical protein, conserved 0.0055 0.0413 0.0729
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0478 0.4996 0.4996
Echinococcus granulosus leucine rich repeat containing protein 47 0.0055 0.0413 0.0413
Brugia malayi CXXC zinc finger family protein 0.0066 0.0537 0.1048
Entamoeba histolytica hypothetical protein 0.0478 0.4996 0.8934
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0052 0.0052
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0432 0.0836
Echinococcus multilocularis transcription factor btf3 0.008 0.0692 0.0692
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0478 0.4996 0.4996
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Echinococcus multilocularis kinase suppressor of Ras 1 0.0478 0.4996 0.4996
Schistosoma mansoni cpg binding protein 0.007 0.0578 0.0578
Brugia malayi Steroid receptor seven-up type 2 0.0023 0.0074 0.0118
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0055 0.0413 0.0651
Loa Loa (eye worm) RGC/RGC protein kinase 0.0478 0.4996 1
Schistosoma mansoni hypothetical protein 0.0039 0.0239 0.0239
Onchocerca volvulus 0.0055 0.0413 0.0688
Loa Loa (eye worm) TK protein kinase 0.0478 0.4996 1
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.0055 0.0413 0.0729
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0692 0.1295
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Entamoeba histolytica leucine-rich repeat containing protein 0.0055 0.0413 0.0651
Echinococcus multilocularis leucine rich repeat containing protein 23 0.0055 0.0413 0.0413
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0478 0.4996 1
Toxoplasma gondii protein kinase domain-containing protein 0.0478 0.4996 1
Entamoeba histolytica serine/threonine kinase, putative 0.0478 0.4996 0.8934
Echinococcus granulosus protein phosphatase 1 regulatory subunit 7 0.0055 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Echinococcus granulosus activin receptor type 0.0478 0.4996 0.4996
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0478 0.4996 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0432 0.0836
Schistosoma mansoni variable lymphocyte receptor 0.0055 0.0413 0.0413
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0074 0.0074
Echinococcus multilocularis Leucine rich repeat domain containing protein 0.0055 0.0413 0.0413
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Schistosoma mansoni protein kinase 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK/Met protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0074 0.0118
Plasmodium falciparum tyrosine kinase-like protein 0.0478 0.4996 1
Echinococcus granulosus transcription factor btf3 0.008 0.0692 0.0692
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0239 0.0449
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Loa Loa (eye worm) TK/RYK protein kinase 0.0478 0.4996 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0074 0.0074
Schistosoma mansoni protein tyrosine kinase 0.0478 0.4996 0.4996
Leishmania major proteophosphoglycan ppg1 0.0055 0.0413 0.0729
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Schistosoma mansoni hypothetical protein 0.0055 0.0413 0.0413
Echinococcus granulosus leucine rich repeat and death domain containing protein 0.0055 0.0413 0.0413
Echinococcus granulosus variable lymphocyte receptor 0.0055 0.0413 0.0413
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0692 0.1295
Echinococcus multilocularis protein phosphatase 1 regulatory subunit 7 0.0055 0.0413 0.0413
Trichomonas vaginalis leucine-rich repeat containing protein, putative 0.0055 0.0413 0.0729
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.0055 0.0413 0.0729
Schistosoma mansoni hypothetical protein 0.0018 0.0015 0.0015
Echinococcus multilocularis variable lymphocyte receptor 0.0055 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0023 0.0074 0.0118
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0041 0.0051
Trichomonas vaginalis leucine-rich repeat containing protein, putative 0.0055 0.0413 0.0729
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0478 0.4996 1
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0413 0.0729
Loa Loa (eye worm) TK/ROR protein kinase 0.0478 0.4996 1
Giardia lamblia Kinase, NEK 0.0478 0.4996 1
Leishmania major dual specificity protein phosphatase, putative 0.0055 0.0413 0.0729
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0074 0.0074
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0478 0.4996 0.4996
Schistosoma mansoni slit 0.0055 0.0413 0.0413
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0478 0.4996 0.4996
Onchocerca volvulus 0.0055 0.0413 0.0688
Schistosoma mansoni hypothetical protein 0.0018 0.0015 0.0015
Loa Loa (eye worm) TK protein kinase 0.0478 0.4996 1
Onchocerca volvulus 0.0478 0.4996 1
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Echinococcus granulosus leucine rich repeat containing protein 15 0.0055 0.0413 0.0413
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0478 0.4996 0.4996
Echinococcus multilocularis leucine rich repeat protein soc 2 0.0055 0.0413 0.0413
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.0055 0.0413 0.0729
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Toxoplasma gondii leucine rich repeat-containing protein 0.0055 0.0413 0.0729
Echinococcus granulosus tumor protein p63 0.0395 0.41 0.41
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Echinococcus multilocularis ephrin type A receptor 4 A 0.0478 0.4996 0.4996
Echinococcus multilocularis epidermal growth factor receptor 0.0478 0.4996 0.4996
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0044 0.0044
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0478 0.4996 0.4996
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0023 0.0074 0.0074
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Schistosoma mansoni hypothetical protein 0.0055 0.0413 0.0413
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Schistosoma mansoni protein kinase 0.0478 0.4996 0.4996
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Schistosoma mansoni protein kinase 0.0478 0.4996 0.4996
Echinococcus multilocularis leucine rich repeat 0.0055 0.0413 0.0413
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0478 0.4996 0.4996
Schistosoma mansoni serine/threonine RGC 0.0478 0.4996 0.4996
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0055 0.0413 0.0651
Trypanosoma cruzi protein phosphatase 1, regulatory subunit, putative 0.0055 0.0413 0.0729
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0478 0.4996 0.4996
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Trichomonas vaginalis leucine-rich repeat-containing protein, putative 0.0055 0.0413 0.0729
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Echinococcus multilocularis tar DNA binding protein 0.0074 0.0624 0.0624
Schistosoma mansoni hypothetical protein 0.0055 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Onchocerca volvulus 0.0478 0.4996 1
Echinococcus multilocularis insulin receptor 0.0478 0.4996 0.4996
Echinococcus granulosus tyrosine kinase 0.0478 0.4996 0.4996
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0074 0.0118
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Echinococcus granulosus cell polarity protein 0.0055 0.0413 0.0413
Echinococcus granulosus leucine rich repeat and calponin y 0.0055 0.0413 0.0413
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0074 0.0118
Entamoeba histolytica serine/threonine kinase, putative 0.0478 0.4996 0.8934
Trichomonas vaginalis TK family protein kinase 0.0478 0.4996 1
Schistosoma mansoni serine/threonine protein kinase 0.0478 0.4996 0.4996
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Entamoeba histolytica hypothetical protein 0.0478 0.4996 0.8934
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Echinococcus multilocularis leucine rich repeat and death domain containing protein 0.0055 0.0413 0.0413
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus multilocularis leucine rich repeat and fibronectin type III 0.0055 0.0413 0.0413
Echinococcus granulosus Leucine rich repeat domain containing protein 0.0055 0.0413 0.0413
Loa Loa (eye worm) TAR-binding protein 0.0074 0.0624 0.1223
Loa Loa (eye worm) TK/ACK protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Trichomonas vaginalis protein phosphatase 2C, putative 0.0055 0.0413 0.0729
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0074 0.0118
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Schistosoma mansoni transcription factor btf3 0.008 0.0692 0.0692
Echinococcus multilocularis cpg binding protein 0.007 0.0578 0.0578
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Trypanosoma brucei Outer row dynein-assembly protein 7 0.0055 0.0413 0.0729
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Schistosoma mansoni leucine-rich repeat protein 0.0055 0.0413 0.0413
Schistosoma mansoni serine/threonine protein kinase 0.0478 0.4996 0.4996
Trichomonas vaginalis leucine-rich repeat-containing protein, putative 0.0055 0.0413 0.0729
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Trichomonas vaginalis protein phosphatase type 2C, putative 0.0055 0.0413 0.0729
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Onchocerca volvulus 0.0058 0.0449 0.0761
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Schistosoma mansoni cpg binding protein 0.0066 0.0537 0.0537
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0055 0.0413 0.0651
Loa Loa (eye worm) hypothetical protein 0.0039 0.0239 0.0449
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0074 0.0118
Entamoeba histolytica leucine rich repeat and phosphatase domain containing protein 0.0055 0.0413 0.0651
Brugia malayi hypothetical protein 0.0478 0.4996 1
Echinococcus granulosus peroxidasin 0.0055 0.0413 0.0413
Brugia malayi Raf kinase 0.0478 0.4996 1
Echinococcus granulosus insulin receptor 0.0478 0.4996 0.4996
Entamoeba histolytica leucine-rich repeat containing protein 0.0055 0.0413 0.0651
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Trichomonas vaginalis protein kinase atn1, putative 0.0478 0.4996 1
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0624 0.0624
Echinococcus granulosus tyrosine protein kinase ABL1 0.0478 0.4996 0.4996
Entamoeba histolytica leucine-rich repeat containing protein 0.0055 0.0413 0.0651
Entamoeba histolytica hypothetical protein 0.0478 0.4996 0.8934
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0478 0.4996 0.4996
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0074 0.0074
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Echinococcus multilocularis natriuretic peptide receptor 1 0.0478 0.4996 0.4996
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0074 0.0074
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0074 0.0118
Brugia malayi SRC-1 0.0478 0.4996 1
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0125 0.1176 0.2273
Brugia malayi Receptor family ligand binding region containing protein 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus multilocularis activated cdc42 kinase 1 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0074 0.0074
Onchocerca volvulus 0.0478 0.4996 1
Plasmodium falciparum protein kinase, putative 0.0478 0.4996 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0074 0.0074
Onchocerca volvulus Slit protein homolog 0.0055 0.0413 0.0688
Trichomonas vaginalis leucine-rich transmembrane protein, putative 0.0055 0.0413 0.0729
Entamoeba histolytica ankyrin repeat protein 0.0478 0.4996 0.8934
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0044 0.0044
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Schistosoma mansoni protein kinase 0.0478 0.4996 0.4996
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0015 0.0015
Trichomonas vaginalis protein phosphatases pp1 regulatory subunit, putative 0.0055 0.0413 0.0729
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Toxoplasma gondii STE kinase 0.0478 0.4996 1
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0624 0.0624
Brugia malayi Immunoglobulin I-set domain containing protein 0.0055 0.0413 0.0798
Loa Loa (eye worm) RGC/RGC protein kinase 0.0478 0.4996 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0478 0.4996 0.4996
Onchocerca volvulus 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Onchocerca volvulus Tyrosine kinase homolog 0.0478 0.4996 1
Echinococcus granulosus tyrosine kinase 0.0478 0.4996 0.4996
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0052 0.5
Trypanosoma cruzi phopshatase, putative 0.0055 0.0413 0.0729
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.4996 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0074 0.0118
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0055 0.0413 0.0413
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0478 0.4996 0.4996
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Entamoeba histolytica leucine-rich repeat containing protein 0.0055 0.0413 0.0651
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Entamoeba histolytica hypothetical protein 0.0083 0.0718 0.1202
Entamoeba histolytica tyrosin kinase, putative 0.0478 0.4996 0.8934
Schistosoma mansoni cellular tumor antigen P53 0.0058 0.0449 0.0449
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Schistosoma mansoni hypothetical protein 0.0018 0.0015 0.0015
Entamoeba histolytica hypothetical protein 0.0478 0.4996 0.8934
Echinococcus multilocularis leucine rich repeat containing protein 0.0055 0.0413 0.0413
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0052 0.5
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0478 0.4996 1
Echinococcus granulosus protein kinase 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Schistosoma mansoni hypothetical protein 0.0055 0.0413 0.0413
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0074 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0074 0.0118
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0052 0.0074
Schistosoma mansoni hypothetical protein 0.0055 0.0413 0.0413
Echinococcus granulosus tyrosine protein kinase Fyn 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) RNA binding protein 0.0074 0.0624 0.1223
Echinococcus multilocularis leucine rich repeat protein 1 0.0055 0.0413 0.0413
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Brugia malayi SH2 domain containing protein 0.0478 0.4996 1
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0074 0.0074
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Onchocerca volvulus 1D304 homolog 0.0055 0.0413 0.0688
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0478 0.4996 0.4996
Schistosoma mansoni protein kinase 0.0478 0.4996 0.4996
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Schistosoma mansoni ephrin receptor 0.0478 0.4996 0.4996
Onchocerca volvulus 0.0478 0.4996 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Giardia lamblia Hypothetical protein 0.0055 0.0413 0.0729
Onchocerca volvulus 0.0478 0.4996 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Schistosoma mansoni shoc2 0.0055 0.0413 0.0413
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0478 0.4996 1
Schistosoma mansoni protein kinase 0.0478 0.4996 0.4996
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0052 0.0074
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0055 0.0413 0.0729
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.4996 1
Echinococcus granulosus integrin linked protein kinase 0.0478 0.4996 0.4996
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus granulosus tyrosine protein kinase csk 0.0478 0.4996 0.4996
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Onchocerca volvulus 0.0478 0.4996 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.014 0.1338 0.1338
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Leishmania major basic transcription factor 3a, putative 0.008 0.0692 0.1295
Loa Loa (eye worm) RGC/RGC protein kinase 0.0478 0.4996 1
Trichomonas vaginalis podocan, putative 0.0055 0.0413 0.0729
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Echinococcus multilocularis transfer RNA-Thr 0.0478 0.4996 0.4996
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0074 0.0074
Entamoeba histolytica hypothetical protein 0.0478 0.4996 0.8934
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0074 0.0118
Echinococcus multilocularis protein kinase 0.0478 0.4996 0.4996
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0478 0.4996 1
Leishmania major hypothetical protein, conserved 0.0055 0.0413 0.0729
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Entamoeba histolytica leucine-rich repeat containing protein 0.0055 0.0413 0.0651
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Brugia malayi beta-NAC-like protein 0.008 0.0692 0.136
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.0055 0.0413 0.0729
Entamoeba histolytica hypothetical protein 0.0083 0.0718 0.1202
Trypanosoma cruzi phopshatase, putative 0.0055 0.0413 0.0729
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus granulosus DEAD box ATP dependent RNA helicase 0.0055 0.0413 0.0413
Giardia lamblia Protein 21.1 0.0478 0.4996 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0478 0.4996 0.4996
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0052 0.0052
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0478 0.4996 1
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0624 0.0624
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0692 0.1295
Loa Loa (eye worm) SRC-1 0.0478 0.4996 1
Leishmania major hypothetical protein, conserved 0.0055 0.0413 0.0729
Echinococcus granulosus tyrosine protein kinase csk 0.0478 0.4996 0.4996
Brugia malayi SH2 domain containing protein 0.0478 0.4996 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0478 0.4996 0.4996
Loa Loa (eye worm) hypothetical protein 0.0023 0.0074 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0074 0.0118
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0478 0.4996 1
Brugia malayi RNA recognition motif domain containing protein 0.0074 0.0624 0.1223
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus granulosus leucine rich repeat containing protein 0.0055 0.0413 0.0413
Schistosoma mansoni hypothetical protein 0.0055 0.0413 0.0413
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Leishmania major protein kinase, putative 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0478 0.4996 1
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Leishmania major hypothetical protein, conserved 0.0055 0.0413 0.0729
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Trypanosoma brucei paraflagellar rod component, putative 0.0055 0.0413 0.0729
Echinococcus multilocularis tyrosine protein kinase shark 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Giardia lamblia hypothetical protein 0.0055 0.0413 0.0729
Echinococcus multilocularis DEAD box ATP dependent RNA helicase 0.0055 0.0413 0.0413
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0413 0.0729
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Trichomonas vaginalis toll, putative 0.0055 0.0413 0.0729
Echinococcus granulosus tyrosine protein kinase Blk 0.0478 0.4996 0.4996
Echinococcus multilocularis Leucine rich repeat, typical subtype 0.0055 0.0413 0.0413
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0478 0.4996 0.4996
Trichomonas vaginalis leucine-rich transmembrane proteins, putative 0.0055 0.0413 0.0729
Echinococcus multilocularis slit 2 protein 0.0055 0.0413 0.0413
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Schistosoma mansoni serine/threonine protein kinase 0.0478 0.4996 0.4996
Schistosoma mansoni hypothetical protein 0.0055 0.0413 0.0413
Echinococcus granulosus leucine rich repeat protein soc 2 0.0055 0.0413 0.0413
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Echinococcus granulosus Leucine rich repeat typical subtype 0.0055 0.0413 0.0413
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0074 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0413 0.0729
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0074 0.0074
Loa Loa (eye worm) serine/threonine protein kinase 0.0478 0.4996 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus granulosus epidermal growth factor receptor 0.0478 0.4996 0.4996
Entamoeba histolytica hypothetical protein 0.0478 0.4996 0.8934
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0413 0.0729
Echinococcus granulosus tyrosine protein kinase HCK 0.0478 0.4996 0.4996
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0478 0.4996 1
Entamoeba histolytica receptor protein kinase, putative 0.0478 0.4996 0.8934
Plasmodium vivax tyrosine kinase-like protein, putative 0.0478 0.4996 1
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Entamoeba histolytica receptor protein kinase, putative 0.0478 0.4996 0.8934
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK protein kinase 0.0478 0.4996 1
Trypanosoma brucei protein kinase, putative 0.0478 0.4996 1
Echinococcus multilocularis protein kinase 0.0478 0.4996 0.4996
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Trichomonas vaginalis protein tyrosine kinase, putative 0.0478 0.4996 1
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus granulosus natriuretic peptide receptor 1 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Echinococcus granulosus leucine rich repeat containing protein 23 0.0055 0.0413 0.0413
Trichomonas vaginalis leucine-rich repeat-containing protein 17, lrc17, putative 0.0055 0.0413 0.0729
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0478 0.4996 0.4996
Plasmodium vivax protein kinase, putative 0.0478 0.4996 1
Trypanosoma brucei kinatase, putative 0.0055 0.0413 0.0729
Entamoeba histolytica tyrosin kinase, putative 0.0478 0.4996 0.8934
Schistosoma mansoni ap endonuclease 0.0021 0.0052 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0624 0.0624
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0533 0.5586 1
Schistosoma mansoni transcription factor LCR-F1 0.0083 0.0718 0.0718
Trichomonas vaginalis AGC family protein kinase 0.0478 0.4996 1
Trichomonas vaginalis protein phosphatase 2C delta isoform, putative 0.0055 0.0413 0.0729
Echinococcus multilocularis leucine rich repeat containing protein 40 0.0055 0.0413 0.0413
Trypanosoma cruzi kinatase, putative 0.0055 0.0413 0.0729
Brugia malayi ras suppressor protein 1 0.0055 0.0413 0.0798
Schistosoma mansoni protein kinase 0.0478 0.4996 0.4996
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0478 0.4996 0.4996
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0478 0.4996 0.4996
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Trichomonas vaginalis STE family protein kinase 0.0478 0.4996 1
Entamoeba histolytica serine/threonine kinase, putative 0.0478 0.4996 0.8934
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Echinococcus granulosus activated cdc42 kinase 1 0.0478 0.4996 0.4996
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0055 0.0413 0.0413
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0478 0.4996 0.4996
Echinococcus multilocularis tyrosine protein kinase pr2 0.0478 0.4996 0.4996
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.4996 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0478 0.4996 1
Echinococcus multilocularis leucine rich repeat and death domain containing protein 0.0055 0.0413 0.0413
Brugia malayi Guanylyl cyclase protein 23 0.0478 0.4996 1
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Echinococcus multilocularis Leucine rich repeat domain containing protein 0.0055 0.0413 0.0413
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0074 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.4996 1
Echinococcus multilocularis tyrosine protein kinase HCK 0.0478 0.4996 0.4996
Echinococcus granulosus leucine rich repeat 0.0055 0.0413 0.0413
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0478 0.4996 1
Echinococcus granulosus Leucine rich repeat domain containing protein 0.0055 0.0413 0.0413
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0074 0.0074
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0055 0.0413 0.0798
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.4996 1
Schistosoma mansoni shoc2 0.0055 0.0413 0.0413
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Echinococcus multilocularis activin receptor type 0.0478 0.4996 0.4996
Entamoeba histolytica transcription factor BTF3, putative 0.008 0.0692 0.1157
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Brugia malayi integrin-linked kinase 0.0478 0.4996 1
Entamoeba histolytica ankyrin repeat protein 0.0478 0.4996 0.8934
Entamoeba histolytica hypothetical protein 0.0478 0.4996 0.8934
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Echinococcus granulosus leucine rich repeat neuronal protein 0.0055 0.0413 0.0413
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Echinococcus granulosus tyrosine protein kinase pr2 0.0478 0.4996 0.4996
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0074 0.0118
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0413 0.0729
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0478 0.4996 0.4996
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0074 0.0118
Brugia malayi nuclear receptor NHR-88 0.0023 0.0074 0.0118
Echinococcus multilocularis tyrosine protein kinase 0.0478 0.4996 0.4996
Leishmania major hypothetical protein, conserved 0.0055 0.0413 0.0729
Schistosoma mansoni retinoic acid receptor RXR 0.0023 0.0074 0.0074
Brugia malayi bone morphogenetic protein type 1 receptor 0.0478 0.4996 1
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0074 0.0074
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0478 0.4996 0.8934
Brugia malayi ras-binding protein SUR-8 0.0055 0.0413 0.0798
Trichomonas vaginalis leucine-rich repeat-containing protein, putative 0.0055 0.0413 0.0729
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0074 0.0118
Trypanosoma brucei dual specificity protein phosphatase, putative 0.0055 0.0413 0.0729
Echinococcus granulosus ras suppressor protein 1 0.0055 0.0413 0.0413
Echinococcus granulosus activated cdc42 kinase 1 0.0478 0.4996 0.4996
Echinococcus multilocularis receptor type guanylyl cyclase 0.0478 0.4996 0.4996
Trichomonas vaginalis toll, putative 0.0055 0.0413 0.0729
Brugia malayi Immunoglobulin I-set domain containing protein 0.0055 0.0413 0.0798
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0074 0.0118
Brugia malayi hypothetical protein 0.0478 0.4996 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0478 0.4996 0.4996
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.4996 1
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Echinococcus granulosus raf serine:threonine protein kinase 0.0478 0.4996 0.4996
Echinococcus multilocularis tyrosine protein kinase csk 0.0478 0.4996 0.4996
Trypanosoma cruzi hypothetical protein, conserved 0.0055 0.0413 0.0729
Echinococcus multilocularis leucine rich repeat protein soc 2 0.0055 0.0413 0.0413
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Schistosoma mansoni protein phosphatases pp1 regulatory subunit 0.0055 0.0413 0.0413
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Brugia malayi hypothetical protein 0.0478 0.4996 1
Onchocerca volvulus 0.0478 0.4996 1
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.4996 1
Schistosoma mansoni flightless-I 0.0055 0.0413 0.0413
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.0055 0.0413 0.0729
Echinococcus multilocularis leucine rich repeat containing protein 47 0.0055 0.0413 0.0413
Echinococcus granulosus leucine rich repeat and fibronectin type III 0.0055 0.0413 0.0413
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Loa Loa (eye worm) PDZ-domain-containing protein scribble 0.0055 0.0413 0.0798
Brugia malayi Leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus granulosus leucine rich repeat containing protein 57 0.0055 0.0413 0.0413
Trichomonas vaginalis conserved hypothetical protein 0.0478 0.4996 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0074 0.0118
Schistosoma mansoni protein kinase 0.0478 0.4996 0.4996
Schistosoma mansoni leucine-rich repeat protein 0.0055 0.0413 0.0413
Onchocerca volvulus 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Brugia malayi Tyrosine-protein kinase PR2 0.0478 0.4996 1
Echinococcus multilocularis GPCR, family 2 0.0018 0.0015 0.0015
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0055 0.0413 0.0729
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Loa Loa (eye worm) TK protein kinase 0.0478 0.4996 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0052 0.5
Loa Loa (eye worm) hypothetical protein 0.0055 0.0413 0.0798
Schistosoma mansoni hypothetical protein 0.0055 0.0413 0.0413
Echinococcus granulosus retinal guanylyl cyclase 2 0.0478 0.4996 0.4996
Giardia lamblia Hypothetical protein 0.0055 0.0413 0.0729
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Leishmania major hypothetical protein, conserved 0.0055 0.0413 0.0729
Entamoeba histolytica hypothetical protein 0.0533 0.5586 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0478 0.4996 0.4996
Brugia malayi Furin-like cysteine rich region family protein 0.0478 0.4996 1
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0478 0.4996 0.4996
Leishmania major proteophosphoglycan ppg3, putative 0.0055 0.0413 0.0729
Loa Loa (eye worm) TK protein kinase 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0478 0.4996 0.8934
Echinococcus granulosus protein flightless 1 0.0055 0.0413 0.0413
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.0055 0.0413 0.0729
Echinococcus multilocularis tyrosine kinase 0.0478 0.4996 0.4996
Echinococcus multilocularis raf serine:threonine protein kinase 0.0478 0.4996 0.4996
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Trichomonas vaginalis leucine-rich transmembrane proteins, putative 0.0055 0.0413 0.0729
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0083 0.0718 0.0718
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0074 0.0118
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0055 0.0413 0.0798
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0074 0.0074
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0478 0.4996 0.4996
Echinococcus granulosus epidermal growth factor receptor 0.0478 0.4996 0.4996
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0023 0.0074 0.0074
Echinococcus granulosus protein tyrosine kinase 0.0478 0.4996 0.4996
Brugia malayi PDZ-domain protein scribble 0.0055 0.0413 0.0798
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0478 0.4996 0.4996
Echinococcus granulosus leucine rich repeat containing protein 70 0.0055 0.0413 0.0413
Schistosoma mansoni ras suppressor protein 1 rsu1 0.0055 0.0413 0.0413
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Plasmodium falciparum protein kinase, putative 0.0478 0.4996 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0478 0.4996 0.4996
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0015 0.0015
Loa Loa (eye worm) histone methyltransferase 0.002 0.0044 0.0057
Leishmania major hypothetical protein, conserved 0.0055 0.0413 0.0729
Giardia lamblia Leucine-rich repeat protein 0.0055 0.0413 0.0729
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0055 0.0413 0.0651
Entamoeba histolytica tyrosine kinase, putative 0.0478 0.4996 0.8934
Loa Loa (eye worm) ICD-1 protein 0.008 0.0692 0.136
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0478 0.4996 0.4996
Brugia malayi Protein kinase domain containing protein 0.0478 0.4996 1
Trypanosoma brucei Pseudokinase, putative 0.0478 0.4996 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0478 0.4996 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0074 0.0118
Echinococcus granulosus slit 2 protein 0.0055 0.0413 0.0413
Trichomonas vaginalis protein phosphatases pp1 regulatory subunit, putative 0.0055 0.0413 0.0729
Echinococcus granulosus tyrosine protein kinase Fyn 0.0478 0.4996 0.4996
Giardia lamblia Kinase 0.0478 0.4996 1
Entamoeba histolytica villidin, putative 0.0055 0.0413 0.0651
Entamoeba histolytica protein kinase domain containing protein 0.0478 0.4996 0.8934
Loa Loa (eye worm) hypothetical protein 0.0478 0.4996 1
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Schistosoma mansoni cpg binding protein 0.007 0.0578 0.0578
Entamoeba histolytica hypothetical protein, conserved 0.0478 0.4996 0.8934
Echinococcus multilocularis Leucine rich repeat, typical subtype 0.0055 0.0413 0.0413
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Trypanosoma cruzi protein kinase, putative 0.0478 0.4996 1
Brugia malayi Peroxidasin 0.0055 0.0413 0.0798
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0478 0.4996 1
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Echinococcus multilocularis leucine rich repeat and calponin y 0.0055 0.0413 0.0413
Loa Loa (eye worm) TK protein kinase 0.0478 0.4996 1
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0478 0.4996 0.4996
Schistosoma mansoni tyrosine protein kinase 0.0478 0.4996 0.4996
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1
Loa Loa (eye worm) TK/INSR protein kinase 0.0478 0.4996 1
Entamoeba histolytica protein kinase, putative 0.0478 0.4996 0.8934
Loa Loa (eye worm) hypothetical protein 0.0058 0.0449 0.087
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0478 0.4996 1
Echinococcus multilocularis leucine rich repeat containing protein 24 0.0055 0.0413 0.0413
Onchocerca volvulus Peroxidasin homolog 0.0055 0.0413 0.0688
Loa Loa (eye worm) hypothetical protein 0.0023 0.0074 0.0118
Loa Loa (eye worm) hypothetical protein 0.0023 0.0074 0.0118
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0055 0.0413 0.0413
Schistosoma mansoni tyrosine kinase 0.0478 0.4996 0.4996
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0478 0.4996 0.4996
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0074 0.0118
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0055 0.0413 0.0651
Trypanosoma brucei transcription factor BTF3, putative 0.008 0.0692 0.1295
Brugia malayi hypothetical protein 0.0055 0.0413 0.0798
Trichomonas vaginalis TKL family protein kinase 0.0478 0.4996 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 81.7 uM Indirect cytotoxicity against human A549 cells co-cultured with human PBMC after 24 hrs by MTT assay ChEMBL. 24518295

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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