Detailed information for compound 1865401

Basic information

Technical information
  • TDR Targets ID: 1865401
  • Name: 2-dimethylaminoethyl tetradecanoate
  • MW: 299.492 | Formula: C18H37NO2
  • H donors: 0 H acceptors: 1 LogP: 6.4 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCC(=O)OCCN(C)C
  • InChi: 1S/C18H37NO2/c1-4-5-6-7-8-9-10-11-12-13-14-15-18(20)21-17-16-19(2)3/h4-17H2,1-3H3
  • InChiKey: WVTLMDGNANZSAT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • tetradecanoic acid 2-dimethylaminoethyl ester
  • myristic acid 2-dimethylaminoethyl ester
  • 43016-78-0
  • NSC83602
  • 2-(Dimethylamino)ethyl myristate
  • EINECS 256-047-4
  • NSC 83602

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Echinococcus multilocularis Tubulin beta 2C chain 0.0059 0.0758 0.0819
Echinococcus granulosus hypothetical protein 0.002 0.0078 0.0078
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 1 1
Echinococcus granulosus tumor protein p63 0.0355 0.5909 0.6436
Schistosoma mansoni tubulin subunit beta 0.0059 0.0758 0.2751
Plasmodium vivax tubulin beta chain, putative 0.0059 0.0758 1
Schistosoma mansoni myosin xvIII 0.002 0.0078 0.0262
Mycobacterium ulcerans hypothetical protein 0.0038 0.0394 0.0774
Leishmania major beta tubulin 0.0059 0.0758 1
Schistosoma mansoni growth hormone secretagogue receptor 0.002 0.0078 0.0262
Loa Loa (eye worm) hypothetical protein 0.0018 0.0054 0.0106
Brugia malayi Trypsin family protein 0.0113 0.1703 0.398
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0162 0.1835
Schistosoma mansoni hypothetical protein 0.0034 0.032 0.1149
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.026 0.0928
Loa Loa (eye worm) hypothetical protein 0.0024 0.0162 0.0316
Echinococcus multilocularis allatostatin A receptor 0.002 0.0078 0.0078
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0394 0.0367
Leishmania major beta tubulin 0.0059 0.0758 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.012 0.1817 0.6627
Loa Loa (eye worm) hypothetical protein 0.0055 0.0702 0.1365
Echinococcus granulosus tubulin alpha chain 0.0023 0.0134 0.0139
Loa Loa (eye worm) tubulin alpha-2 chain 0.0023 0.0134 0.026
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0394 0.0774
Echinococcus multilocularis peregrin 0.003 0.026 0.0277
Leishmania major alpha tubulin 0.0023 0.0134 0.1443
Onchocerca volvulus 0.002 0.0078 0.0125
Leishmania major beta tubulin 0.0059 0.0758 1
Brugia malayi Dopamine receptor 0.002 0.0078 0.0182
Mycobacterium tuberculosis Conserved protein 0.0038 0.0394 0.0774
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0113 0.1703 0.6214
Entamoeba histolytica tubulin family protein 0.0059 0.0758 0.0732
Entamoeba histolytica tubulin gamma chain 0.0023 0.0134 0.0106
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0394 0.4824
Brugia malayi beta-tubulin, identical 0.0059 0.0758 0.1771
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0229 0.0445
Loa Loa (eye worm) hypothetical protein 0.0018 0.0054 0.0106
Loa Loa (eye worm) hypothetical protein 0.0034 0.032 0.0623
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Loa Loa (eye worm) BEN-1 protein 0.0059 0.0758 0.1475
Onchocerca volvulus 0.0018 0.0043 0.0037
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0078 0.0262
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0273 0.029
Loa Loa (eye worm) hypothetical protein 0.0024 0.0162 0.0316
Echinococcus multilocularis aldo keto reductase 0.0017 0.0028 0.0024
Brugia malayi Bromodomain containing protein 0.003 0.026 0.0608
Echinococcus multilocularis g-protein coupled receptor 0.002 0.0078 0.0078
Brugia malayi beta-lactamase family protein 0.0038 0.0394 0.092
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0273 0.0974
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0197 0.202
Brugia malayi neuropeptide F receptor 0.002 0.0078 0.0182
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0017 0.0028 0.0066
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0215 0.3477 0.6766
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.002 0.0078 0.0152
Echinococcus granulosus orexin receptor type 2 0.002 0.0078 0.0078
Giardia lamblia Alpha-tubulin 0.0023 0.0134 0.0106
Schistosoma mansoni histamine h1 receptor 0.002 0.0078 0.0262
Schistosoma mansoni alpha tubulin 0.0023 0.0134 0.0465
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0078 0.0262
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0078 0.0078
Loa Loa (eye worm) beta-tubulin 0.0059 0.0758 0.1475
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0394 0.5009
Echinococcus granulosus Tubulin alpha 1 chain 0.0023 0.0134 0.0139
Brugia malayi neuropeptide F receptor 0.002 0.0078 0.0182
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0099 0.1452 0.1576
Leishmania major alpha tubulin 0.0023 0.0134 0.1443
Schistosoma mansoni hypothetical protein 0.002 0.0078 0.0262
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0162 0.0134
Leishmania major beta tubulin 0.0059 0.0758 1
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0229 0.0534
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0078 0.0262
Echinococcus multilocularis g protein coupled receptor 0.002 0.0078 0.0078
Brugia malayi follicle stimulating hormone receptor 0.0261 0.428 1
Schistosoma mansoni tubulin subunit alpha 0.0023 0.0134 0.0465
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0465 0.05
Echinococcus granulosus tubulin alpha 1C chain 0.0023 0.0134 0.0139
Plasmodium falciparum phd finger protein, putative 0.003 0.026 0.2923
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0028 0.0024
Echinococcus granulosus tubulin subunit TubB 0.0023 0.0134 0.0139
Leishmania major beta tubulin 0.0059 0.0758 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0059 0.0758 0.0819
Trypanosoma brucei beta tubulin 0.0059 0.0758 1
Echinococcus granulosus Tubulin beta 2C chain 0.0059 0.0758 0.0819
Loa Loa (eye worm) hypothetical protein 0.0172 0.2738 0.5328
Echinococcus multilocularis alpha 1A adrenergic receptor 0.002 0.0078 0.0078
Trichomonas vaginalis tubulin gamma chain, putative 0.0023 0.0134 0.0106
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0078 0.0262
Schistosoma mansoni calcium-activated potassium channel 0.0111 0.1673 0.6101
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0273 0.3348
Echinococcus multilocularis G-protein coupled receptor, putative 0.002 0.0078 0.0078
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0078 0.0152
Schistosoma mansoni hypothetical protein 0.0018 0.0043 0.0133
Echinococcus multilocularis tubulin alpha chain 0.0023 0.0134 0.0139
Echinococcus multilocularis tubulin alpha 3 chain 0.0023 0.0134 0.0139
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Trichomonas vaginalis tubulin alpha chain, putative 0.0059 0.0758 0.0732
Echinococcus multilocularis tubulin gamma 1 chain 0.0023 0.0134 0.0139
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0078 0.0262
Echinococcus granulosus fmrfamide receptor 0.002 0.0078 0.0078
Brugia malayi Protein kinase domain containing protein 0.0019 0.0066 0.0154
Schistosoma mansoni amine GPCR 0.002 0.0078 0.0262
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0078 0.0262
Schistosoma mansoni aldo-keto reductase 0.0017 0.0028 0.008
Schistosoma mansoni hypothetical protein 0.002 0.0078 0.0262
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0028 0.0024
Schistosoma mansoni neuropeptide receptor 0.002 0.0078 0.0262
Onchocerca volvulus 0.0031 0.0273 0.0616
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.002 0.0078 0.0078
Schistosoma mansoni amine GPCR 0.002 0.0078 0.0262
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0162 0.0379
Entamoeba histolytica hypothetical protein 0.0036 0.0368 0.0341
Schistosoma mansoni biogenic amine receptor 0.002 0.0078 0.0262
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.002 0.0078 0.0262
Schistosoma mansoni alpha tubulin 0.0023 0.0134 0.0465
Echinococcus multilocularis tubulin epsilon chain 0.0023 0.0134 0.0139
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0162 0.0284
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0162 0.0379
Schistosoma mansoni tubulin subunit alpha 0.0023 0.0134 0.0465
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0028 0.0024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0134 0.026
Echinococcus granulosus thyrotropin releasing hormone receptor 0.002 0.0078 0.0078
Leishmania major alpha tubulin 0.0023 0.0134 0.1443
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0197 0.2306
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0078 0.0078
Trypanosoma brucei beta tubulin 0.0059 0.0758 1
Loa Loa (eye worm) hypothetical protein 0.031 0.5138 1
Brugia malayi jmjC domain containing protein 0.0099 0.1452 0.3393
Schistosoma mansoni intermediate filament proteins 0.0028 0.0229 0.0814
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0078 0.0262
Echinococcus multilocularis neuropeptide receptor A26 0.0543 0.9177 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0078 0.0078
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0028 0.0024
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0078 0.0262
Leishmania major beta tubulin 0.0059 0.0758 1
Leishmania major beta tubulin 0.0059 0.0758 1
Leishmania major alpha tubulin 0.0023 0.0134 0.1443
Echinococcus multilocularis peroxisome assembly protein 26 0.0023 0.0134 0.0139
Leishmania major alpha tubulin 0.0023 0.0134 0.1443
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0162 0.0284
Echinococcus multilocularis aldo keto reductase 0.0017 0.0028 0.0024
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0162 0.0284
Brugia malayi intermediate filament protein 0.0028 0.0229 0.0534
Schistosoma mansoni tubulin subunit epsilon 0.0023 0.0134 0.0465
Brugia malayi G protein-coupled receptor F59B2.13 0.002 0.0078 0.0182
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.1444 0.5264
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 1 1
Brugia malayi Tubulin beta-1 chain 0.0059 0.0758 0.1771
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Echinococcus multilocularis fmrfamide receptor 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Brugia malayi RE15519p 0.002 0.0078 0.0182
Brugia malayi hypothetical protein 0.002 0.0078 0.0182
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0394 0.0367
Trichomonas vaginalis tubulin beta chain, putative 0.0023 0.0134 0.0106
Brugia malayi Pre-SET motif family protein 0.0031 0.0273 0.0637
Echinococcus granulosus neuropeptide receptor A26 0.0543 0.9177 1
Schistosoma mansoni hypothetical protein 0.003 0.026 0.0928
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Trichomonas vaginalis tubulin gamma chain, putative 0.0023 0.0134 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0019 0.0066 0.0218
Onchocerca volvulus 0.0028 0.0229 0.0505
Schistosoma mansoni calcium-activated potassium channel 0.0172 0.2738 1
Schistosoma mansoni biogenic amine receptor 0.002 0.0078 0.0262
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0007 0.0013
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.1444 0.1568
Echinococcus multilocularis Tubulin alpha 1 chain 0.0023 0.0134 0.0139
Brugia malayi sulfakinin receptor protein 0.002 0.0078 0.0182
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0028 0.0024
Onchocerca volvulus 0.002 0.0078 0.0125
Brugia malayi Melatonin receptor type 1A 0.002 0.0078 0.0182
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0368 0.0394
Plasmodium falciparum alpha tubulin 2 0.0023 0.0134 0.1124
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0017 0.0028 0.0066
Echinococcus granulosus G protein coupled receptor 139 0.002 0.0078 0.0078
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0465 0.05
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0273 0.0974
Echinococcus multilocularis somatostatin receptor 0.002 0.0078 0.0078
Onchocerca volvulus 0.002 0.0078 0.0125
Toxoplasma gondii beta-tubulin, putative 0.0059 0.0758 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.037 0.0721
Echinococcus multilocularis tubulin alpha 1C chain 0.0023 0.0134 0.0139
Loa Loa (eye worm) hypothetical protein 0.0038 0.0394 0.0766
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0078 0.0078
Schistosoma mansoni aldo-keto reductase 0.0017 0.0028 0.008
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.037 0.0397
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.002 0.0078 0.0262
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0018 0.0054 0.0106
Echinococcus multilocularis tumor protein p63 0.0355 0.5909 0.6436
Echinococcus multilocularis beta tubulin 0.0059 0.0758 0.0819
Echinococcus granulosus aldo keto reductase 0.0017 0.0028 0.0024
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0241 0.3938 0.8281
Loa Loa (eye worm) melatonin receptor type 1A 0.002 0.0078 0.0152
Loa Loa (eye worm) hypothetical protein 0.0024 0.0162 0.0316
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0162 0.0134
Brugia malayi Serotonin/octopamine receptor family protein 7 0.002 0.0078 0.0182
Loa Loa (eye worm) hypothetical protein 0.0038 0.0394 0.0766
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Echinococcus granulosus g protein coupled receptor 0.002 0.0078 0.0078
Echinococcus granulosus Tubulin alpha 1 chain 0.0023 0.0134 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0078 0.0262
Echinococcus multilocularis tubulin alpha 0.0023 0.0134 0.0139
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.002 0.0078 0.0078
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0818 0.1592
Loa Loa (eye worm) tubulin alpha chain 0.0023 0.0134 0.026
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0162 0.0284
Loa Loa (eye worm) BEN-1 protein 0.0059 0.0758 0.1475
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0078 0.0078
Schistosoma mansoni tubulin subunit beta 0.0059 0.0758 0.2751
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0288 0.475 1
Trypanosoma brucei beta tubulin 0.0059 0.0758 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0162 0.0284
Brugia malayi hypothetical protein 0.0019 0.0066 0.0154
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0078 0.0262
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0394 0.0774
Trichomonas vaginalis set domain proteins, putative 0.0245 0.3994 0.3977
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0078 0.0078
Leishmania major alpha tubulin 0.0023 0.0134 0.1443
Trypanosoma cruzi tubulin gamma chain 0.0023 0.0134 0.1443
Echinococcus granulosus g-protein coupled receptor 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Entamoeba histolytica tubulin alpha chain, putative 0.0023 0.0134 0.0106
Brugia malayi hypothetical protein 0.002 0.0078 0.0182
Loa Loa (eye worm) hypothetical protein 0.0017 0.0028 0.0055
Plasmodium falciparum tubulin beta chain 0.0059 0.0758 1
Schistosoma mansoni neuropeptide receptor 0.002 0.0078 0.0262
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 1 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0273 0.029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Echinococcus granulosus neuropeptide FF receptor 2 0.002 0.0078 0.0078
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0078 0.0152
Echinococcus multilocularis small conductance calcium activated potassium 0.0172 0.2738 0.2978
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0028 0.0024
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Loa Loa (eye worm) hypothetical protein 0.0019 0.0066 0.0128
Echinococcus multilocularis neuropeptide receptor 0.002 0.0078 0.0078
Schistosoma mansoni jumonji domain containing protein 0.0078 0.11 0.4002
Loa Loa (eye worm) hypothetical protein 0.0059 0.0757 0.1473
Leishmania major alpha tubulin 0.0023 0.0134 0.1443
Loa Loa (eye worm) tubulin alpha chain 0.0023 0.0134 0.026
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.002 0.0078 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0078 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0078 0.0078
Echinococcus multilocularis g protein coupled receptor 0.002 0.0078 0.0078
Mycobacterium tuberculosis Conserved protein 0.0038 0.0394 0.0774
Echinococcus granulosus tachykinin peptides receptor 99D 0.002 0.0078 0.0078
Brugia malayi G protein-coupled receptor 0.002 0.0078 0.0182
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.1444 0.5264
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0591 0.115
Giardia lamblia Beta tubulin 0.0059 0.0758 0.0732
Giardia lamblia Gamma tubulin 0.0023 0.0134 0.0106
Schistosoma mansoni adenoreceptor 0.002 0.0078 0.0262
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0394 0.0422
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0078 0.0078
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0078 0.0262
Echinococcus multilocularis tubulin alpha 3 chain 0.0023 0.0134 0.0139
Loa Loa (eye worm) hypothetical protein 0.0038 0.0394 0.0766
Plasmodium falciparum tubulin gamma chain 0.0023 0.0134 0.1124
Plasmodium vivax tubulin alpha chain, putative 0.0023 0.0134 0.1124
Onchocerca volvulus 0.0019 0.0066 0.0095
Echinococcus granulosus Tubulin alpha 1 chain 0.0023 0.0134 0.0139
Schistosoma mansoni hypothetical protein 0.002 0.0078 0.0262
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Loa Loa (eye worm) PHD-finger family protein 0.003 0.026 0.0506
Brugia malayi putative neuropeptide receptor 0.002 0.0078 0.0182
Toxoplasma gondii alpha tubulin TUBA1 0.0023 0.0134 0.1443
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0037 0.0019
Onchocerca volvulus 0.002 0.0078 0.0125
Schistosoma mansoni neuropeptide receptor 0.002 0.0078 0.0262
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0083
Echinococcus multilocularis tubulin subunit beta 0.0059 0.0758 0.0819
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.002 0.0078 0.0078
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 1 1
Echinococcus multilocularis musashi 0.0028 0.0229 0.0242
Brugia malayi hypothetical protein 0.002 0.0078 0.0182
Brugia malayi hypothetical protein 0.0017 0.0033 0.0078
Loa Loa (eye worm) hypothetical protein 0.0018 0.0054 0.0106
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0078 0.0262
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0591 0.138
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.002 0.0078 0.0078
Echinococcus granulosus neuropeptide s receptor 0.0543 0.9177 1
Schistosoma mansoni amine GPCR 0.002 0.0078 0.0262
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0394 0.0774
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0037 0.0019
Schistosoma mansoni alpha-1 adrenergic receptor 0.002 0.0078 0.0262
Mycobacterium tuberculosis Conserved protein 0.0038 0.0394 0.0774
Trichomonas vaginalis tubulin epsilon chain, putative 0.0023 0.0134 0.0106
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0394 0.5009
Plasmodium vivax hypothetical protein, conserved 0.003 0.026 0.2923
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.026 0.3176
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.002 0.0078 0.0078
Leishmania major alpha tubulin 0.0023 0.0134 0.1443
Leishmania major beta tubulin 0.0059 0.0758 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0054 0.0055
Loa Loa (eye worm) tubulin beta-4 chain 0.0059 0.0758 0.1475
Brugia malayi Tubulin alpha-2 chain 0.0023 0.0134 0.0312
Echinococcus granulosus aldo keto reductase 0.0017 0.0028 0.0024
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0078 0.0078
Echinococcus granulosus 7TM GPCR rhodopsin 0.002 0.0078 0.0078
Schistosoma mansoni biogenic amine receptor 0.002 0.0078 0.0262
Trichomonas vaginalis tubulin epsilon chain, putative 0.0059 0.0758 0.0732
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.002 0.0078 0.0182
Loa Loa (eye worm) hypothetical protein 0.0026 0.0197 0.0383
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0394 0.1418
Echinococcus granulosus Tubulin beta 2C chain 0.0059 0.0758 0.0819
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0028 0.0024
Brugia malayi tubulin alpha-2 chain 0.0023 0.0134 0.0312
Echinococcus granulosus Tubulin beta 2C chain 0.0059 0.0758 0.0819
Leishmania major epsilon tubulin, putative 0.0023 0.0134 0.1443
Echinococcus multilocularis neuropeptide s receptor 0.0543 0.9177 1
Onchocerca volvulus 0.0024 0.0162 0.0338
Echinococcus granulosus Tubulin beta 2C chain 0.0059 0.0758 0.0819
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0261 0.428 0.833
Leishmania major beta tubulin 0.0059 0.0758 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0023 0.0134 0.0106
Leishmania major beta tubulin 0.0059 0.0758 1
Schistosoma mansoni hypothetical protein 0.0036 0.0368 0.1324
Echinococcus granulosus tubulin alpha chain 0.0023 0.0134 0.0139
Leishmania major gamma-tubulin 0.0023 0.0134 0.1443
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0028 0.0024
Loa Loa (eye worm) hypothetical protein 0.0113 0.1703 0.3315
Echinococcus multilocularis beta tubulin 0.0059 0.0758 0.0819
Echinococcus granulosus hypothetical protein 0.0017 0.0028 0.0024
Schistosoma mansoni hypothetical protein 0.0019 0.0066 0.0218
Echinococcus granulosus beta tubulin 0.0059 0.0758 0.0819
Mycobacterium ulcerans beta-lactamase 0.0038 0.0394 0.0774
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0078 0.0078
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0394 0.0367
Leishmania major beta tubulin 0.0059 0.0758 1
Echinococcus multilocularis lamin dm0 0.0028 0.0229 0.0242
Echinococcus granulosus peroxisome assembly protein 26 0.0023 0.0134 0.0139
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.002 0.0078 0.0078
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0078 0.0078
Entamoeba histolytica hypothetical protein 0.0036 0.0368 0.0341
Onchocerca volvulus 0.0038 0.0394 0.0922
Echinococcus multilocularis Tubulin beta 2C chain 0.0059 0.0758 0.0819
Brugia malayi Dopamine receptor protein 2 0.002 0.0078 0.0182
Brugia malayi hypothetical protein 0.002 0.0078 0.0182
Echinococcus multilocularis tubulin alpha chain 0.0023 0.0134 0.0139
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0054 0.5
Schistosoma mansoni tubulin subunit alpha 0.0023 0.0134 0.0465
Echinococcus granulosus g protein coupled receptor 0.002 0.0078 0.0078
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0394 0.0422
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0394 0.092
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Leishmania major alpha tubulin 0.0023 0.0134 0.1443
Echinococcus multilocularis MAM 0.0019 0.0066 0.0065
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0288 0.475 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0078 0.0262
Onchocerca volvulus 0.002 0.0078 0.0125
Echinococcus granulosus tubulin alpha 3 chain 0.0023 0.0134 0.0139
Echinococcus multilocularis Tubulin alpha 1 chain 0.0023 0.0134 0.0139
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Brugia malayi Dopamine receptor protein 1 0.002 0.0078 0.0182
Echinococcus granulosus g protein coupled receptor 0.002 0.0078 0.0078
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0394 0.0367
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0028 0.0024
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Plasmodium vivax tubulin gamma chain, putative 0.0023 0.0134 0.1124
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.002 0.0078 0.0078
Onchocerca volvulus 0.002 0.0078 0.0125
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.026 0.0277
Onchocerca volvulus 0.002 0.0078 0.0125
Loa Loa (eye worm) hypothetical protein 0.0049 0.0591 0.115
Giardia lamblia Beta tubulin 0.0059 0.0758 0.0732
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.002 0.0078 0.0125
Echinococcus granulosus lamin dm0 0.0028 0.0229 0.0242
Trypanosoma brucei alpha tubulin 0.0023 0.0134 0.1443
Brugia malayi Muscle positioning protein 4 0.0018 0.0043 0.01
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Echinococcus granulosus lamin 0.0028 0.0229 0.0242
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.032 0.0748
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0253 0.0269
Toxoplasma gondii beta tubulin 0.0059 0.0758 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0028 0.0024
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0288 0.475 1
Toxoplasma gondii ABC1 family protein 0.0038 0.0394 0.5009
Schistosoma mansoni alpha tubulin 0.0023 0.0134 0.0465
Echinococcus multilocularis tachykinin peptides receptor 99D 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Onchocerca volvulus 0.0038 0.0394 0.0922
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.002 0.0078 0.0182
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0078 0.0262
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0078 0.0078
Trypanosoma cruzi epsilon tubulin, putative 0.0023 0.0134 0.1443
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0078 0.0078
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0394 0.0766
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0078 0.0078
Trichomonas vaginalis tubulin beta chain, putative 0.0023 0.0134 0.0106
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0162 0.0379
Trypanosoma cruzi beta tubulin, putative 0.0059 0.0758 1
Onchocerca volvulus 0.0113 0.1703 0.4225
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0037 0.0019
Trypanosoma brucei alpha tubulin 0.0023 0.0134 0.1443
Echinococcus granulosus 7tm_1 domain containing protein 0.002 0.0078 0.0078
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0078 0.0078
Echinococcus granulosus tubulin beta 4A class IVa 0.0059 0.0758 0.0819
Echinococcus multilocularis neuropeptide receptor 0.002 0.0078 0.0078
Onchocerca volvulus 0.0019 0.0066 0.0095
Leishmania major hypothetical protein, conserved 0.0026 0.0197 0.2306
Brugia malayi Tubulin gamma chain 0.0023 0.0134 0.0312
Loa Loa (eye worm) hypothetical protein 0.0053 0.0652 0.1269
Loa Loa (eye worm) TYRA-2 protein 0.002 0.0078 0.0152
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0099 0.1452 0.1576
Leishmania major hypothetical protein, conserved 0.0038 0.0394 0.5009
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0273 0.0974
Schistosoma mansoni amine GPCR 0.002 0.0078 0.0262
Leishmania major beta tubulin 0.0059 0.0758 1
Brugia malayi beta-lactamase 0.0038 0.0394 0.092
Trypanosoma brucei epsilon tubulin 0.0023 0.0134 0.1443
Trichomonas vaginalis tubulin gamma chain, putative 0.0059 0.0758 0.0732
Brugia malayi Tachykinin-like peptides receptor 99D 0.002 0.0078 0.0182
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0037 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Toxoplasma gondii alpha-tubulin I, putative 0.0023 0.0134 0.1443
Plasmodium vivax SET domain protein, putative 0.0031 0.0273 0.3101
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0078 0.0262
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Leishmania major beta tubulin 0.0059 0.0758 1
Schistosoma mansoni hypothetical protein 0.002 0.0078 0.0262
Loa Loa (eye worm) tubulin beta-2A chain 0.0059 0.0758 0.1475
Schistosoma mansoni lamin 0.0028 0.0229 0.0814
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.026 0.3176
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0028 0.0024
Echinococcus multilocularis serotonin receptor 0.002 0.0078 0.0078
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.064 0.2318
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0078 0.0078
Echinococcus multilocularis lamin 0.0028 0.0229 0.0242
Brugia malayi G-protein coupled receptor 0.002 0.0078 0.0182
Entamoeba histolytica hypothetical protein 0.0036 0.0368 0.0341
Brugia malayi GnHR receptor homolog 0.002 0.0078 0.0182
Brugia malayi hypothetical protein 0.002 0.0078 0.0182
Onchocerca volvulus 0.002 0.0078 0.0125
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0394 0.1418
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0028 0.0024
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.059 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0078 0.0078
Trypanosoma brucei tubulin gamma chain 0.0023 0.0134 0.1443
Schistosoma mansoni tubulin subunit beta 0.0059 0.0758 0.2751
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.037 0.1332
Echinococcus multilocularis Tubulin beta 2C chain 0.0059 0.0758 0.0819
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0028 0.0024
Onchocerca volvulus 0.002 0.0078 0.0125
Echinococcus multilocularis tubulin alpha chain 0.0023 0.0134 0.0139
Echinococcus multilocularis fmrfamide receptor 0.002 0.0078 0.0078
Plasmodium falciparum alpha tubulin 1 0.0023 0.0134 0.1124
Onchocerca volvulus 0.002 0.0078 0.0125
Onchocerca volvulus 0.002 0.0078 0.0125
Echinococcus granulosus tubulin alpha 0.0023 0.0134 0.0139
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.002 0.0078 0.0262
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0078 0.0078
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0078 0.0152
Onchocerca volvulus 0.002 0.0078 0.0125
Brugia malayi Serotonin receptor 0.002 0.0078 0.0182
Echinococcus multilocularis tubulin beta 1 chain 0.0059 0.0758 0.0819
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0078 0.0152
Echinococcus granulosus neuropeptide receptor 0.002 0.0078 0.0078
Echinococcus granulosus tubulin alpha 1C chain 0.0023 0.0134 0.0139
Brugia malayi hypothetical protein 0.002 0.0078 0.0182
Schistosoma mansoni tubulin subunit beta 0.0059 0.0758 0.2751
Trypanosoma cruzi epsilon tubulin, putative 0.0023 0.0134 0.1443
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0273 0.029
Plasmodium falciparum tubulin epsilon chain, putative 0.0023 0.0134 0.1124
Giardia lamblia PHD finger protein 15 0.003 0.026 0.0232
Brugia malayi tubulin alpha chain - mouse 0.0023 0.0134 0.0312
Brugia malayi hypothetical protein 0.0026 0.0197 0.0459
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.1444 0.1568
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.1839 0.3579
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0162 0.0284
Echinococcus multilocularis Tubulin beta 2C chain 0.0059 0.0758 0.0819
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0162 0.0134
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0007 0.0015
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Echinococcus granulosus small conductance calcium activated potassium 0.0172 0.2738 0.2978
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 1 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.037 0.0397
Echinococcus granulosus alpha tubulin 0.0023 0.0134 0.0139
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0394 0.0774
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.1444 0.5264
Onchocerca volvulus 0.0018 0.0043 0.0037
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.1444 0.1568
Leishmania major beta tubulin 0.0059 0.0758 1
Loa Loa (eye worm) oxidoreductase 0.0017 0.0028 0.0055
Brugia malayi G-protein coupled receptor 0.002 0.0078 0.0182
Leishmania major beta tubulin 0.0059 0.0758 1
Echinococcus multilocularis aldo keto reductase 0.0017 0.0028 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0078 0.0078
Leishmania major alpha tubulin 0.0023 0.0134 0.1443
Loa Loa (eye worm) hypothetical protein 0.0052 0.064 0.1245
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0078 0.0078
Trichomonas vaginalis tubulin epsilon chain, putative 0.0059 0.0758 0.0732
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0028 0.0024
Brugia malayi SEA domain containing protein 0.0018 0.0043 0.01
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0078 0.0078
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0078 0.0262
Onchocerca volvulus 0.0018 0.0043 0.0037
Loa Loa (eye worm) hypothetical protein 0.0038 0.0394 0.0766
Loa Loa (eye worm) oxidoreductase 0.0017 0.0028 0.0055
Schistosoma mansoni tubulin subunit beta 0.0059 0.0758 0.2751
Entamoeba histolytica tubulin family protein 0.0059 0.0758 0.0732
Echinococcus multilocularis serotonin receptor 0.002 0.0078 0.0078
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0162 0.1835
Brugia malayi ORL1-like opioid receptor 0.002 0.0078 0.0182
Onchocerca volvulus 0.0018 0.0043 0.0037
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0054 0.0055
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.037 0.1332
Brugia malayi beta-lactamase family protein 0.0038 0.0394 0.092
Echinococcus granulosus sex peptide receptor 0.002 0.0078 0.0078
Schistosoma mansoni tubulin subunit beta 0.0059 0.0758 0.2751
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.002 0.0078 0.0262
Onchocerca volvulus Alhambra homolog 0.003 0.026 0.0584
Echinococcus multilocularis G protein coupled receptor 139 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0066 0.0128
Trypanosoma cruzi alpha tubulin, putative 0.0023 0.0134 0.1443
Treponema pallidum fructose-bisphosphate aldolase 0.059 1 0.5
Loa Loa (eye worm) tubulin gamma chain 0.0023 0.0134 0.026
Schistosoma mansoni amine GPCR 0.002 0.0078 0.0262
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0162 0.0284
Mycobacterium leprae Probable lipase LipE 0.0038 0.0394 0.0774
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0028 0.0024
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.002 0.0078 0.0182
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Brugia malayi larval opioid receptor 0.002 0.0078 0.0182
Brugia malayi Tubulin alpha-2 chain 0.0023 0.0134 0.0312
Onchocerca volvulus Neuropeptide F receptor homolog 0.002 0.0078 0.0125
Onchocerca volvulus 0.0104 0.1542 0.3816
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0591 0.138
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0078 0.0078
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0197 0.202
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0394 0.0774
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.1444 0.1568
Echinococcus granulosus neuropeptide receptor 0.002 0.0078 0.0078
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0078 0.0078
Plasmodium vivax tubulin epsilon chain, putative 0.0023 0.0134 0.1124
Loa Loa (eye worm) hypothetical protein 0.0031 0.0273 0.0531
Trichomonas vaginalis tubulin beta chain, putative 0.0023 0.0134 0.0106
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Loa Loa (eye worm) tubulin beta-1 chain 0.0059 0.0758 0.1475
Echinococcus granulosus allatostatin A receptor 0.002 0.0078 0.0078
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0197 0.2306
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0197 0.202
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0017 0.0028 0.0066
Loa Loa (eye worm) hypothetical protein 0.0038 0.0394 0.0766
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.002 0.0078 0.0152
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0078 0.0078
Brugia malayi hypothetical protein 0.002 0.0078 0.0182
Loa Loa (eye worm) oxidoreductase 0.0017 0.0028 0.0055
Echinococcus granulosus tubulin beta 1 chain 0.0059 0.0758 0.0819
Onchocerca volvulus 0.0028 0.0229 0.0505
Onchocerca volvulus 0.002 0.0078 0.0125
Loa Loa (eye worm) hypothetical protein 0.0038 0.0394 0.0766
Loa Loa (eye worm) oxidoreductase 0.0017 0.0028 0.0055
Mycobacterium ulcerans hypothetical protein 0.0024 0.0162 0.0284
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0229 0.0445
Onchocerca volvulus 0.0245 0.3994 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.002 0.0078 0.0078
Giardia lamblia Beta tubulin 0.0059 0.0758 0.0732
Onchocerca volvulus 0.0052 0.064 0.1541
Echinococcus multilocularis dro:myosuppressin receptor 0.002 0.0078 0.0078
Schistosoma mansoni neuropeptide f receptor 76f 0.002 0.0078 0.0262
Echinococcus granulosus intermediate filament protein 0.0028 0.0229 0.0242
Loa Loa (eye worm) hypothetical protein 0.0019 0.0066 0.0128
Loa Loa (eye worm) hypothetical protein 0.031 0.5138 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Schistosoma mansoni opsin-like receptor 0.002 0.0078 0.0262
Schistosoma mansoni neuropeptide receptor 0.002 0.0078 0.0262
Trypanosoma brucei beta tubulin 0.0059 0.0758 1
Entamoeba histolytica hypothetical protein 0.0036 0.0368 0.0341
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0078 0.0078
Brugia malayi jmjC domain containing protein 0.0036 0.037 0.0865
Loa Loa (eye worm) hypothetical protein 0.0052 0.0634 0.1235
Brugia malayi hypothetical protein 0.002 0.0078 0.0182
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0013
Mycobacterium ulcerans lipase LipD 0.0038 0.0394 0.0774
Trichomonas vaginalis esterase, putative 0.0038 0.0394 0.0367
Schistosoma mansoni lamin 0.0028 0.0229 0.0814
Trichomonas vaginalis tubulin epsilon chain, putative 0.0023 0.0134 0.0106
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0078 0.0078
Schistosoma mansoni tubulin subunit gamma 0.0023 0.0134 0.0465
Brugia malayi alpha-tubulin 0.0023 0.0134 0.0312
Loa Loa (eye worm) hypothetical protein 0.0113 0.1703 0.3315
Trichomonas vaginalis tubulin alpha chain, putative 0.0023 0.0134 0.0106
Echinococcus granulosus alpha 1A adrenergic receptor 0.002 0.0078 0.0078
Loa Loa (eye worm) oxidoreductase 0.0017 0.0028 0.0055
Echinococcus granulosus tubulin alpha chain 0.0023 0.0134 0.0139
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.002 0.0078 0.0262
Brugia malayi hypothetical protein 0.002 0.0078 0.0182
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0023 0.0134 0.1443
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.002 0.0078 0.0152
Schistosoma mansoni pol-related 0.0017 0.0028 0.008
Giardia lamblia Fructose-bisphosphate aldolase 0.059 1 1
Trichomonas vaginalis tubulin beta chain, putative 0.0023 0.0134 0.0106
Trichomonas vaginalis tubulin, putative 0.0059 0.0758 0.0732
Trypanosoma brucei epsilon tubulin 0.0023 0.0134 0.1443
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0078 0.0262
Trichomonas vaginalis tubulin beta chain, putative 0.0023 0.0134 0.0106
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0028 0.0024
Brugia malayi Tubulin alpha chain 0.0023 0.0134 0.0312
Echinococcus granulosus tubulin alpha 3 chain 0.0023 0.0134 0.0139
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0273 0.0974
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Brugia malayi Serotonin receptor 0.002 0.0078 0.0182
Onchocerca volvulus 0.002 0.0078 0.0125
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0394 0.0774
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0162 0.0284
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0078 0.0078
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0028 0.0024
Echinococcus multilocularis Tubulin alpha 1 chain 0.0023 0.0134 0.0139
Brugia malayi gonadotropin-releasing hormone receptor 2 0.002 0.0078 0.0182
Echinococcus multilocularis aldo keto reductase 0.0017 0.0028 0.0024
Echinococcus multilocularis tubulin alpha chain 0.0023 0.0134 0.0139
Echinococcus granulosus tubulin gamma 1 chain 0.0023 0.0134 0.0139
Echinococcus multilocularis hypothetical protein 0.0023 0.0134 0.0139
Echinococcus granulosus dro:myosuppressin receptor 0.002 0.0078 0.0078
Leishmania major alpha tubulin 0.0023 0.0134 0.1443
Loa Loa (eye worm) TK/ALK protein kinase 0.0019 0.0066 0.0128
Echinococcus granulosus aldo keto reductase 0.0017 0.0028 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0078 0.0078
Echinococcus granulosus serotonin receptor 0.002 0.0078 0.0078
Toxoplasma gondii beta-1 tubulin, putative 0.0059 0.0758 1
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0059 0.0758 0.0819
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0368 0.1324
Loa Loa (eye worm) hypothetical protein 0.0018 0.0054 0.0106
Echinococcus granulosus somatostatin receptor 0.002 0.0078 0.0078
Trichomonas vaginalis tubulin beta chain, putative 0.0059 0.0758 0.0732
Plasmodium vivax tubulin alpha chain, putative 0.0023 0.0134 0.1124
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0028 0.0024
Trypanosoma brucei epsilon tubulin 0.0023 0.0134 0.1443
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0162 0.0284
Loa Loa (eye worm) beta-lactamase 0.0038 0.0394 0.0766
Echinococcus multilocularis biogenic amine (5HT) receptor 0.002 0.0078 0.0078
Brugia malayi hypothetical protein 0.002 0.0078 0.0182
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0394 0.5009
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0083
Brugia malayi Pre-SET motif family protein 0.0215 0.3477 0.8123
Schistosoma mansoni hypothetical protein 0.0172 0.2738 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.002 0.0078 0.0152
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0017 0.0028 0.0024
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.002 0.0078 0.0078
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0017 0.0028 0.0024
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0394 0.0774
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0394 0.0774
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0007 0.0015
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0394 0.0367
Trypanosoma brucei alpha tubulin 0.0023 0.0134 0.1443
Brugia malayi AKH receptor 0.002 0.0078 0.0182
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.002 0.0078 0.0262
Leishmania major beta tubulin 0.0059 0.0758 1
Echinococcus multilocularis tubulin alpha 1C chain 0.0023 0.0134 0.0139
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0197 0.2306
Brugia malayi putative neuropeptide receptor NPR1 0.002 0.0078 0.0182
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0394 0.0774
Trypanosoma brucei alpha tubulin 0.0023 0.0134 0.1443
Loa Loa (eye worm) alpha-tubulin 0.0023 0.0134 0.026
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0368 0.0394
Echinococcus multilocularis orexin receptor type 2 0.002 0.0078 0.0078
Echinococcus granulosus peregrin 0.003 0.026 0.0277
Entamoeba histolytica tubulin alpha-1 chain 0.0023 0.0134 0.0106
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0078 0.0262
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0078 0.0078
Schistosoma mansoni opsin-like receptor 0.002 0.0078 0.0262
Echinococcus multilocularis tubulin subunit TubB 0.0023 0.0134 0.0139
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.002 0.0078 0.0262
Onchocerca volvulus 0.0018 0.0043 0.0037
Giardia lamblia Alpha-tubulin 0.0023 0.0134 0.0106
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0197 0.2306
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Leishmania major alpha tubulin 0.0023 0.0134 0.1443
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0394 0.0774
Brugia malayi hypothetical protein 0.0036 0.0368 0.086
Brugia malayi PHD-finger family protein 0.003 0.026 0.0608
Onchocerca volvulus 0.0038 0.0394 0.0922
Onchocerca volvulus 0.002 0.0078 0.0125
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Loa Loa (eye worm) hypothetical protein 0.0028 0.0229 0.0445
Trichomonas vaginalis tubulin beta chain, putative 0.0023 0.0134 0.0106
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.0152
Echinococcus granulosus tubulin epsilon chain 0.0023 0.0134 0.0139
Echinococcus multilocularis sex peptide receptor 0.002 0.0078 0.0078
Echinococcus granulosus MAM 0.0019 0.0066 0.0065
Echinococcus granulosus beta tubulin 0.0059 0.0758 0.0819
Loa Loa (eye worm) DOMON domain-containing protein 0.0018 0.0043 0.0083
Echinococcus granulosus peptide allatostatin:somatostatin 0.002 0.0078 0.0078
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0162 0.0284
Onchocerca volvulus 0.002 0.0078 0.0125
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.1444 0.2811
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.1839 0.3579
Echinococcus granulosus tubulin alpha chain 0.0023 0.0134 0.0139
Leishmania major beta tubulin 0.0059 0.0758 1
Loa Loa (eye worm) tubulin beta chain 0.0059 0.0758 0.1475
Schistosoma mansoni peptide (allatostatin)-like receptor 0.002 0.0078 0.0262
Brugia malayi MH2 domain containing protein 0.0121 0.1839 0.4297
Echinococcus granulosus tubulin subunit beta 0.0059 0.0758 0.0819
Leishmania major beta tubulin 0.0059 0.0758 1
Loa Loa (eye worm) hypothetical protein 0.003 0.026 0.0506
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0017 0.0028 0.0066
Echinococcus multilocularis tubulin alpha chain 0.0023 0.0134 0.0139
Echinococcus granulosus tubulin alpha chain 0.0023 0.0134 0.0139
Trypanosoma brucei beta tubulin 0.0023 0.0134 0.1443
Onchocerca volvulus 0.002 0.0078 0.0125
Echinococcus granulosus Tubulin beta 2C chain 0.0059 0.0758 0.0819
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0162 0.1835
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0162 0.0284
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.026 0.0277
Loa Loa (eye worm) hypothetical protein 0.0028 0.022 0.0428
Schistosoma mansoni opsin-like receptor 0.002 0.0078 0.0262
Echinococcus multilocularis g protein coupled receptor 0.002 0.0078 0.0078
Loa Loa (eye worm) alpha-tubulin 0.0023 0.0134 0.026
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.1444 0.3374

Activities

Activity type Activity value Assay description Source Reference
IZ (functional) = 0 cm Antifungal activity against yeast AD1-8u expressing Candida albicans CaCdr1p by agar disk diffusion assay ChEMBL. 20739103
IZ (functional) = 0 cm Antifungal activity against yeast AD1-8u expressing Candida albicans CaMdr1p by agar disk diffusion assay ChEMBL. 20739103

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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