Detailed information for compound 1999265

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 436.494 | Formula: C21H23F3N4OS
  • H donors: 2 H acceptors: 2 LogP: 4.4 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCc1ccc(nc1)C(=O)Nc1ccc(c(c1)[C@@]1(C)N=C(N)SCC1(F)F)F
  • InChi: 1S/C21H23F3N4OS/c1-3-4-5-13-6-9-17(26-11-13)18(29)27-14-7-8-16(22)15(10-14)20(2)21(23,24)12-30-19(25)28-20/h6-11H,3-5,12H2,1-2H3,(H2,25,28)(H,27,29)/t20-/m1/s1
  • InChiKey: HZVDYOJJNKICNT-HXUWFJFHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens beta-site APP-cleaving enzyme 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni memapsin-2 (A01 family) Get druggable targets OG5_135830 All targets in OG5_135830
Schistosoma japonicum ko:K07747 beta-site APP-cleaving enzyme 2 (memapsin 1) [EC3.4.23.45], putative Get druggable targets OG5_135830 All targets in OG5_135830
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum plasmepsin VII beta-site APP-cleaving enzyme 1 401 aa 352 aa 21.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0063 0.0202 0.0202
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.2516 1 1
Echinococcus granulosus intermediate filament protein 0.0028 0.0061 0.0199
Brugia malayi aspartic protease BmAsp-1, identical 0.0021 0.0033 0.0033
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0033 0.0106
Loa Loa (eye worm) nuclear receptor NHR-67 0.0043 0.0119 0.0119
Brugia malayi beta-lactamase 0.0037 0.0098 0.0098
Trichomonas vaginalis ap endonuclease, putative 0.0063 0.0202 0.0202
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.2516 1 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0107 0.0107
Plasmodium falciparum plasmepsin VII 0.0021 0.0033 0.0795
Loa Loa (eye worm) hypothetical protein 0.009 0.031 0.031
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.2516 1 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Brugia malayi ecdysone receptor 0.0043 0.0119 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.009 0.031 0.031
Trichomonas vaginalis rotamase, putative 0.0034 0.0084 0.0084
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.014 0.014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.009 0.031 0.0431
Brugia malayi intermediate filament protein 0.0028 0.0061 0.0061
Brugia malayi hypothetical protein 0.0143 0.0519 0.0519
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0033 0.0106
Schistosoma mansoni nuclear receptor 0.0043 0.0119 0.0391
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.009 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0037 0.0098 0.0098
Onchocerca volvulus 0.003 0.0068 0.0068
Trypanosoma cruzi hypothetical protein, conserved 0.0776 0.3047 1
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.0018 0.0022 0.0073
Onchocerca volvulus 0.0021 0.0033 0.0033
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0222 0.0725
Schistosoma mansoni thyroid hormone receptor 0.009 0.031 0.1016
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.009 0.031 0.0431
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1364 0.5397 0.5397
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0033 0.0106
Plasmodium vivax pyruvate kinase, putative 0.0115 0.0409 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0107 0.0375 0.1227
Brugia malayi serine/threonine-protein kinase plk-2 0.0107 0.0375 0.0375
Treponema pallidum fructose-bisphosphate aldolase 0.1364 0.5397 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.014 0.014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0222 0.0125
Onchocerca volvulus 0.0043 0.0119 0.0119
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1364 0.5397 0.5397
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0375 0.0375
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0098 0.0322
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0143 0.0519 0.0519
Loa Loa (eye worm) hypothetical protein 0.0037 0.0098 0.0098
Schistosoma mansoni hypothetical protein 0.0018 0.0022 0.0073
Brugia malayi orphan nuclear receptor NR2E1 0.0043 0.0119 0.0119
Schistosoma mansoni memapsin-2 (A01 family) 0.0521 0.203 0.6642
Echinococcus granulosus Nuclear hormone receptor HR96 0.0043 0.0119 0.0391
Brugia malayi pyruvate kinase, muscle isozyme 0.0024 0.0046 0.0046
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0043 0.0119 0.0391
Brugia malayi conserved hypotetical protein 0.0043 0.0119 0.0119
Loa Loa (eye worm) beta-lactamase 0.0037 0.0098 0.0098
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0043 0.0119 0.0119
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.009 0.031 0.0431
Brugia malayi Nuclear hormone receptor-like 1 0.009 0.031 0.031
Onchocerca volvulus 0.0037 0.0098 0.0098
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0162 0.053
Loa Loa (eye worm) nuclear hormone receptor 0.0043 0.0119 0.0119
Schistosoma mansoni hypothetical protein 0.0018 0.0022 0.0073
Giardia lamblia Fructose-bisphosphate aldolase 0.1364 0.5397 0.5397
Brugia malayi Nuclear hormone receptor family member nhr-40 0.009 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0022
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0181 0.0181
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.0222 0.0321
Trichomonas vaginalis pyruvate kinase, putative 0.0115 0.0409 0.0409
Loa Loa (eye worm) hypothetical protein 0.009 0.031 0.031
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.009 0.031 0.1016
Schistosoma mansoni cathepsin D (A01 family) 0.0021 0.0033 0.0106
Echinococcus granulosus expressed protein 0.0035 0.0087 0.0286
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0009 0.0009
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0033 0.0106
Brugia malayi Pyruvate kinase, M2 isozyme 0.0115 0.0409 0.0409
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0048 0.014 0.014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1364 0.5397 0.5397
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0048 0.014 0.0458
Schistosoma mansoni pyruvate kinase 0.0115 0.0409 0.1338
Echinococcus granulosus pyruvate kinase 0.0059 0.0185 0.0606
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0162 0.053
Echinococcus granulosus microtubule associated protein 2 0.0778 0.3056 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0033 0.0106
Echinococcus multilocularis lamin 0.0028 0.0061 0.0084
Plasmodium falciparum plasmepsin V 0.0021 0.0033 0.0795
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0087 0.0087
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.009 0.031 0.1016
Trypanosoma brucei protein kinase, putative 0.0053 0.0162 0.053
Schistosoma mansoni hypothetical protein 0.016 0.0586 0.1919
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0098 0.0321
Entamoeba histolytica hypothetical protein 0.016 0.0586 0.0586
Schistosoma mansoni nuclear receptor nhr-48 0.0043 0.0119 0.0391
Echinococcus granulosus geminin 0.0197 0.0737 0.2412
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0021 0.0033 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0161 0.0161
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0776 0.3047 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.009 0.031 0.1016
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.0222 0.0727
Echinococcus multilocularis thyroid hormone receptor alpha 0.009 0.031 0.0431
Brugia malayi beta-lactamase family protein 0.0037 0.0098 0.0098
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0021 0.0033 0.0033
Schistosoma mansoni RAR-like nuclear receptor 0.009 0.031 0.1016
Schistosoma mansoni cpg binding protein 0.003 0.0068 0.0223
Plasmodium falciparum plasmepsin III 0.0021 0.0033 0.0795
Loa Loa (eye worm) pyruvate kinase 0.0115 0.0409 0.0409
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0162 0.0162
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.009 0.031 0.1016
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0063 0.0202 0.0202
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0063 0.0202 0.0202
Plasmodium vivax basic transcription factor 3b, putative 0.0075 0.0249 0.61
Plasmodium vivax aspartyl proteinase, putative 0.0021 0.0033 0.0795
Brugia malayi nuclear receptor RXR 0.0043 0.0119 0.0119
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0098 0.0142
Toxoplasma gondii pyruvate kinase PyK1 0.0115 0.0409 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0162 0.053
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0666 0.261 0.2537
Mycobacterium ulcerans pyruvate kinase 0.0115 0.0409 0.0314
Trypanosoma brucei polo-like protein kinase 0.0107 0.0375 0.123
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.009 0.031 0.031
Schistosoma mansoni ap endonuclease 0.0063 0.0202 0.066
Trypanosoma brucei pyruvate kinase 1 0.0115 0.0409 0.1342
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1364 0.5397 0.5397
Loa Loa (eye worm) hypothetical protein 0.009 0.031 0.031
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0162 0.0529
Toxoplasma gondii aspartyl protease ASP3 0.0021 0.0033 0.0795
Entamoeba histolytica hypothetical protein 0.016 0.0586 0.0586
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0119 0.0391
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.2516 1 1
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0776 0.3047 0.3047
Loa Loa (eye worm) hypothetical protein 0.009 0.031 0.031
Schistosoma mansoni rotamase 0.0035 0.0087 0.0286
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0162 0.053
Schistosoma mansoni hypothetical protein 0.004 0.0107 0.0352
Trypanosoma brucei pyruvate kinase 1, putative 0.0115 0.0409 0.1342
Chlamydia trachomatis pyruvate kinase 0.0115 0.0409 0.5
Plasmodium falciparum plasmepsin IX 0.0021 0.0033 0.0795
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.009 0.031 0.031
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0175 0.4268
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0119 0.0391
Onchocerca volvulus 0.0043 0.0119 0.0119
Entamoeba histolytica hypothetical protein 0.016 0.0586 0.0586
Schistosoma mansoni pyruvate kinase 0.0059 0.0185 0.0606
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.009 0.031 0.1016
Loa Loa (eye worm) hypothetical protein 0.0115 0.0409 0.0409
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0059
Brugia malayi steroid hormone receptor 0.009 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Plasmodium falciparum plasmepsin X 0.0021 0.0033 0.0795
Leishmania major pyruvate kinase 0.0115 0.0409 0.1342
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0239 0.0903 0.1308
Leishmania major pyruvate kinase 0.0115 0.0409 0.1342
Loa Loa (eye worm) hypothetical protein 0.0048 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0063 0.0202 0.0105
Loa Loa (eye worm) hypothetical protein 0.009 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0037 0.0098 0.0098
Entamoeba histolytica transcription factor BTF3, putative 0.0075 0.0249 0.0249
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0119 0.0166
Trichomonas vaginalis rotamase, putative 0.0035 0.0087 0.0087
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0098 0.0098
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0043 0.0119 0.0119
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0098 0.0098
Brugia malayi exodeoxyribonuclease III family protein 0.0063 0.0202 0.0202
Schistosoma mansoni ap endonuclease 0.0063 0.0202 0.066
Loa Loa (eye worm) pyruvate kinase-PB 0.008 0.027 0.027
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0003 0.0004
Brugia malayi nuclear hormone receptor 0.009 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Onchocerca volvulus 0.009 0.031 0.031
Plasmodium falciparum pyruvate kinase 2 0.0059 0.0185 0.4525
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0033 0.0106
Onchocerca volvulus Pyruvate kinase homolog 0.0115 0.0409 0.0409
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0061 0.0061
Brugia malayi photoreceptor-specific nuclear receptor 0.009 0.031 0.031
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0021 0.0033 0.0795
Echinococcus multilocularis expressed protein 0.0035 0.0087 0.0121
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0375 0.0375
Brugia malayi MAP kinase sur-1 0.0053 0.0162 0.0162
Onchocerca volvulus Bile acid receptor homolog 0.009 0.031 0.031
Schistosoma mansoni nuclear receptor 0.0043 0.0119 0.0391
Echinococcus multilocularis pyruvate kinase 0.0059 0.0185 0.0257
Echinococcus multilocularis musashi 0.0028 0.0061 0.0084
Loa Loa (eye worm) ICD-1 protein 0.0075 0.0249 0.0249
Brugia malayi beta-NAC-like protein 0.0075 0.0249 0.0249
Plasmodium falciparum plasmepsin II 0.0021 0.0033 0.0795
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0162 0.0529
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0043 0.0119 0.0166
Echinococcus granulosus nuclear receptor 2DBD gamma 0.009 0.031 0.1016
Schistosoma mansoni nuclear hormone receptor 0.009 0.031 0.1016
Brugia malayi CXXC zinc finger family protein 0.003 0.0068 0.0068
Brugia malayi Nuclear hormone receptor E75 0.0043 0.0119 0.0119
Brugia malayi pyruvate kinase 0.0024 0.0046 0.0046
Brugia malayi nuclear hormone receptor family member odr-7 0.0043 0.0119 0.0119
Onchocerca volvulus Pyruvate kinase homolog 0.0115 0.0409 0.0409
Entamoeba histolytica protein tyrosine phosphatase, putative 0.2516 1 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0084 0.0276
Schistosoma mansoni steroid hormone receptor ad4bp 0.009 0.031 0.1016
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0162 0.0162
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0162 0.0162
Echinococcus granulosus Nuclear hormone receptor HR96 0.0043 0.0119 0.0391
Brugia malayi Nuclear hormone receptor family member nhr-19 0.009 0.031 0.031
Trypanosoma brucei transcription factor BTF3, putative 0.0075 0.0249 0.0819
Schistosoma mansoni cathepsin D (A01 family) 0.0021 0.0033 0.0106
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0033 0.0106
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0035 0.0088 0.0088
Toxoplasma gondii exonuclease III APE 0.0063 0.0202 0.4935
Brugia malayi Nuclear hormone receptor family member nhr-14 0.009 0.031 0.031
Brugia malayi nuclear receptor NHR-88 0.009 0.031 0.031
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0098 0.0322
Trypanosoma cruzi hypothetical protein, conserved 0.0776 0.3047 1
Schistosoma mansoni lamin 0.0028 0.0061 0.0199
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0021 0.0033 0.0106
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0003 0.0009
Echinococcus granulosus FTZ F1 alpha 0.009 0.031 0.1016
Brugia malayi hypothetical protein 0.0043 0.0119 0.0119
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1815 0.7199 1
Echinococcus granulosus pyruvate kinase 0.0059 0.0185 0.0606
Brugia malayi tailless protein 0.0043 0.0119 0.0119
Onchocerca volvulus 0.0028 0.0061 0.0061
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0222 0.0125
Onchocerca volvulus Serine\/threonine kinase homolog 0.0107 0.0375 0.0375
Loa Loa (eye worm) pyruvate kinase 0.0115 0.0409 0.0409
Echinococcus granulosus retinoic acid receptor rxr beta a 0.009 0.031 0.1016
Schistosoma mansoni lamin 0.0028 0.0061 0.0199
Entamoeba histolytica hypothetical protein 0.016 0.0586 0.0586
Trichomonas vaginalis esterase, putative 0.0037 0.0098 0.0098
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Onchocerca volvulus 0.0037 0.0098 0.0098
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-49 0.009 0.031 0.031
Onchocerca volvulus 0.0037 0.0098 0.0098
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0084 0.0276
Echinococcus multilocularis microtubule associated protein 2 0.0778 0.3056 0.4245
Loa Loa (eye worm) aspartyl protease 6 0.0021 0.0033 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-19 0.009 0.031 0.031
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.014 0.014
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0098 0.0321
Onchocerca volvulus Protein ultraspiracle homolog 0.009 0.031 0.031
Brugia malayi Nuclear hormone receptor family member nhr-31 0.009 0.031 0.031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.009 0.031 0.031
Schistosoma mansoni cpg binding protein 0.0032 0.0075 0.0245
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0043 0.0119 0.0391
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.009 0.031 0.0431
Onchocerca volvulus 0.0028 0.0061 0.0061
Brugia malayi nuclear hormone receptor family member nhr-6 0.0043 0.0119 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0375 0.0375
Plasmodium falciparum basic transcription factor 3b, putative 0.0075 0.0249 0.61
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.0222 0.0725
Loa Loa (eye worm) hypothetical protein 0.0037 0.0098 0.0098
Echinococcus multilocularis geminin 0.0197 0.0737 0.1024
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0084 0.0084
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0033 0.0106
Trypanosoma cruzi pyruvate kinase 2, putative 0.0115 0.0409 0.1342
Leishmania major basic transcription factor 3a, putative 0.0075 0.0249 0.0819
Loa Loa (eye worm) hypothetical protein 0.008 0.027 0.027
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0087 0.0087
Loa Loa (eye worm) steroid hormone receptor 0.009 0.031 0.031
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.009 0.031 0.1016
Schistosoma mansoni cpg binding protein 0.0032 0.0075 0.0245
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0087 0.0087
Brugia malayi hypothetical protein 0.016 0.0586 0.0586
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.009 0.031 0.031
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0063 0.0202 0.066
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.2516 1 1
Schistosoma mansoni transcription factor btf3 0.0075 0.0249 0.0816
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Giardia lamblia Pyruvate kinase 0.0059 0.0185 0.0185
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0098 0.0322
Echinococcus granulosus ecdysone induced protein 78C 0.009 0.031 0.1016
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.009 0.031 0.1016
Leishmania major hypothetical protein, conserved 0.0037 0.0098 0.0322
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0022 0.0031
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0063 0.0202 0.028
Schistosoma mansoni kinase 0.0054 0.0166 0.0544
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0107 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Brugia malayi hypothetical protein 0.0021 0.0033 0.0033
Echinococcus granulosus nuclear receptor 2DBD gamma 0.009 0.031 0.1016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1364 0.5397 0.5397
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0162 0.0224
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0048 0.014 0.0194
Echinococcus multilocularis pyruvate kinase 0.0091 0.0312 0.0433
Loa Loa (eye worm) hypothetical protein 0.0058 0.0181 0.0181
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0022 0.0022
Trypanosoma cruzi transcription factor btf3, putative 0.0075 0.0249 0.0819
Trypanosoma cruzi polo-like protein kinase, putative 0.0107 0.0375 0.123
Brugia malayi nuclear receptor RXR 0.0048 0.014 0.014
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0162 0.0162
Trypanosoma cruzi transcription factor btf3, putative 0.0075 0.0249 0.0819
Echinococcus multilocularis pyruvate kinase 0.0059 0.0185 0.0257
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0119 0.0391
Brugia malayi nuclear receptor NHR-88 0.0043 0.0119 0.0119
Plasmodium vivax aspartyl protease, putative 0.0021 0.0033 0.0795
Trichomonas vaginalis ap endonuclease, putative 0.0063 0.0202 0.0202
Onchocerca volvulus 0.0021 0.0033 0.0033
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.009 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0022 0.0073
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Schistosoma mansoni retinoic acid receptor RXR 0.009 0.031 0.1016
Schistosoma mansoni microtubule-associated protein tau 0.0778 0.3056 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0043 0.0119 0.0166
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0162 0.3951
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0021 0.0033 0.0106
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0162 0.0529
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.2516 1 1
Echinococcus granulosus dnaJ subfamily B 0.0425 0.1645 0.5382
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0063 0.0202 0.5
Mycobacterium leprae Probable pyruvate kinase PykA 0.0115 0.0409 0.1237
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0084 0.2058
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0063 0.0202 0.4935
Toxoplasma gondii aspartyl protease 0.0021 0.0033 0.0795
Plasmodium vivax plasmepsin IV, putative 0.0021 0.0033 0.0795
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0033
Brugia malayi Steroid receptor seven-up type 2 0.009 0.031 0.031
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.009 0.031 0.0431
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0098 0.0098
Brugia malayi ecdysteroid receptor 0.009 0.031 0.031
Plasmodium falciparum plasmepsin VIII, putative 0.0021 0.0033 0.0795
Echinococcus multilocularis FTZ F1 alpha 0.009 0.031 0.0431
Echinococcus granulosus pyruvate kinase 0.0059 0.0185 0.0606
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1364 0.5397 0.5397
Brugia malayi Nuclear hormone receptor family member nhr-3 0.009 0.031 0.031
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0098 0.0142
Toxoplasma gondii aspartyl protease ASP1 0.0021 0.0033 0.0795
Brugia malayi Pyruvate kinase, muscle isozyme 0.0115 0.0409 0.0409
Echinococcus granulosus transcription factor btf3 0.0075 0.0249 0.0816
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0181 0.0181
Loa Loa (eye worm) pyruvate kinase 0.0024 0.0046 0.0046
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0222 0.0725
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.0222 0.0308
Plasmodium vivax pyruvate kinase 2, putative 0.0059 0.0185 0.4525
Echinococcus multilocularis pyruvate kinase 0.0059 0.0185 0.0257
Brugia malayi nuclear hormone receptor 0.0043 0.0119 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Schistosoma mansoni coup transcription factor 0.009 0.031 0.1016
Toxoplasma gondii pyruvate kinase PyKII 0.0059 0.0185 0.4525
Echinococcus granulosus pyruvate kinase 0.0115 0.0409 0.1338
Brugia malayi Pepsin A precursor 0.0021 0.0033 0.0033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.009 0.031 0.031
Schistosoma mansoni pyruvate kinase 0.0115 0.0409 0.1338
Echinococcus multilocularis dnaJ subfamily B 0.0425 0.1645 0.2285
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0098 0.0142
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.009 0.031 0.031
Trypanosoma cruzi pyruvate kinase 2, putative 0.0115 0.0409 0.1342
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0098 0.0142
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0375 0.0375
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1364 0.5397 0.5397
Onchocerca volvulus 0.2516 1 1
Trichomonas vaginalis pyruvate kinase, putative 0.0115 0.0409 0.0409
Echinococcus multilocularis GPCR, family 2 0.0018 0.0022 0.0031
Entamoeba histolytica hypothetical protein 0.0075 0.0249 0.0249
Brugia malayi aspartic protease BmAsp-2, identical 0.0021 0.0033 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0375 0.0375
Plasmodium vivax aspartyl protease, putative 0.0021 0.0033 0.0795
Brugia malayi Nuclear hormone receptor family member nhr-41 0.009 0.031 0.031
Echinococcus granulosus cpg binding protein 0.0032 0.0075 0.0245
Brugia malayi nuclear receptor NHR-67 0.0043 0.0119 0.0119
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1364 0.5397 0.5397
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0009 0.0009
Trypanosoma cruzi polo-like protein kinase, putative 0.0107 0.0375 0.123
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0666 0.261 0.3782
Plasmodium falciparum plasmepsin IV 0.0021 0.0033 0.0795
Schistosoma mansoni Tr4/Tr2 (homologue) 0.009 0.031 0.1016
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0098 0.0142
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0098 0.0142
Mycobacterium tuberculosis Conserved protein 0.0037 0.0098 0.0142
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0063 0.0202 0.0292
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.0222 0.5417
Schistosoma mansoni hypothetical protein 0.0425 0.1645 0.5382
Schistosoma mansoni hypothetical protein 0.0018 0.0022 0.0073
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0048 0.014 0.0458
Brugia malayi Nuclear hormone receptor family member nhr-25 0.009 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0119
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.009 0.031 0.031
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.009 0.031 0.0431
Entamoeba histolytica pyruvate kinase, putative 0.008 0.027 0.027
Echinococcus multilocularis pyruvate kinase 0.0115 0.0409 0.0568
Echinococcus granulosus lamin 0.0028 0.0061 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0249 0.0249
Plasmodium vivax plasmepsin V, putative 0.0021 0.0033 0.0795
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0037 0.0098 0.0098
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.016 0.0586 0.0815
Entamoeba histolytica protein tyrosine phosphatase, putative 0.2516 1 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0048 0.014 0.0458
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0022 0.0073
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0162 0.0162
Echinococcus multilocularis pyruvate kinase 0.0115 0.0409 0.0568
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0162 0.0162
Schistosoma mansoni intermediate filament proteins 0.0028 0.0061 0.0199
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0043 0.0119 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-1 0.009 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0048 0.014 0.014
Echinococcus multilocularis ecdysone induced protein 78C 0.009 0.031 0.0431
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0063 0.0202 0.0662
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0098 0.0142
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.174 0.6902 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0063 0.0202 0.0662
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.2516 1 1
Echinococcus granulosus nuclear receptor nhr 48 0.0043 0.0119 0.0391
Loa Loa (eye worm) DR-78 0.0043 0.0119 0.0119
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0068 0.0068
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0063 0.0202 0.4935
Plasmodium falciparum pyruvate kinase 0.0115 0.0409 1
Echinococcus multilocularis cpg binding protein 0.0032 0.0075 0.0104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1364 0.5397 0.5397
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0021 0.0033 0.0045
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0022 0.0031
Schistosoma mansoni zinc finger protein 0.0043 0.0119 0.0391
Loa Loa (eye worm) hypothetical protein 0.009 0.031 0.031
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0375 0.1227
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0161 0.0161
Schistosoma mansoni hypothetical protein 0.0197 0.0737 0.2412
Schistosoma mansoni retinoid-x-receptor (RXR) 0.009 0.031 0.1016
Entamoeba histolytica serine/threonine protein kinase, putative 0.0107 0.0375 0.0375
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1364 0.5397 0.5397
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0162 0.053
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0098 0.2402
Toxoplasma gondii NAC domain-containing protein 0.0075 0.0249 0.61
Loa Loa (eye worm) hypothetical protein 0.0143 0.0519 0.0519
Plasmodium vivax aspartyl protease, putative 0.0021 0.0033 0.0795
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.016 0.0586 0.1919
Brugia malayi Nuclear hormone receptor family member nhr-25 0.009 0.031 0.031
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0043 0.0119 0.0166
Loa Loa (eye worm) hypothetical protein 0.0048 0.014 0.014
Onchocerca volvulus Huntingtin homolog 0.0143 0.0519 0.0519
Echinococcus granulosus GPCR family 2 0.0018 0.0022 0.0073
Brugia malayi Nuclear hormone receptor E75 0.0043 0.0119 0.0119
Mycobacterium tuberculosis Conserved protein 0.0037 0.0098 0.0142
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.009 0.031 0.1016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.009 0.031 0.031
Echinococcus granulosus lamin dm0 0.0028 0.0061 0.0199
Trichomonas vaginalis CAMK family protein kinase 0.0107 0.0375 0.0375
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0107 0.0107
Treponema pallidum exodeoxyribonuclease (exoA) 0.0063 0.0202 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0249 0.0249
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0043 0.0119 0.0391
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0084 0.0276
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0063 0.0202 0.0662
Brugia malayi hypothetical protein 0.0048 0.014 0.014
Giardia lamblia Pyruvate kinase 0.0115 0.0409 0.0409
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0107 0.0375 0.0521
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0061 0.0061
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0021 0.0033 0.0033
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0022 0.0022
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0021 0.0033 0.0795
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0098 0.0136
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0162 0.0224
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0043 0.0119 0.0166
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0776 0.3047 0.3047
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.2516 1 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0222 0.0125
Loa Loa (eye worm) hypothetical protein 0.0048 0.014 0.014
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0162 0.053
Onchocerca volvulus Huntingtin homolog 0.0143 0.0519 0.0519
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0098 0.0098
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0162 0.053
Schistosoma mansoni transcription factor LCR-F1 0.016 0.0586 0.1919
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0666 0.261 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0098 0.0098
Brugia malayi hypothetical protein 0.0048 0.014 0.014
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0202 0.0659
Brugia malayi beta-lactamase family protein 0.0037 0.0098 0.0098
Echinococcus multilocularis nuclear receptor nhr 48 0.0043 0.0119 0.0166
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0063 0.0202 0.0662
Loa Loa (eye worm) pyruvate kinase 0.0115 0.0409 0.0409
Brugia malayi Eukaryotic aspartyl protease family protein 0.0021 0.0033 0.0033
Plasmodium vivax aspartyl proteinase, putative 0.0021 0.0033 0.0795
Leishmania major hypothetical protein, conserved 0.0776 0.3047 1
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.2516 1 1
Echinococcus multilocularis lamin dm0 0.0028 0.0061 0.0084
Brugia malayi hypothetical protein 0.0043 0.0119 0.0119
Schistosoma mansoni hypothetical protein 0.0197 0.0737 0.2412
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0043 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0061
Schistosoma mansoni thyroid hormone receptor 0.009 0.031 0.1016
Onchocerca volvulus Pyruvate kinase homolog 0.0115 0.0409 0.0409
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0022 0.0022
Giardia lamblia Kinase, PLK 0.0107 0.0375 0.0375
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0115 0.0409 0.0593
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.009 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0033
Echinococcus granulosus pyruvate kinase 0.0115 0.0409 0.1338
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0098 0.0321
Echinococcus granulosus thyroid hormone receptor alpha 0.0043 0.0119 0.0391
Plasmodium falciparum plasmepsin I 0.0021 0.0033 0.0795
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0084 0.0276
Plasmodium falciparum plasmepsin VI 0.0021 0.0033 0.0795
Brugia malayi hypothetical protein 0.0021 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0037 0.0098 0.0098
Toxoplasma gondii ABC1 family protein 0.0037 0.0098 0.2402
Echinococcus multilocularis transcription factor btf3 0.0075 0.0249 0.0347
Mycobacterium tuberculosis Conserved protein 0.0037 0.0098 0.0142
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0107 0.0375 0.123

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 870 nM BindingDB_Patents: Inhibition Assay. Inhibition assay using human BACE-1. ChEMBL. No reference
IC50 (binding) = 870 nM BindingDB_Patents: Inhibition Assay. Beta-Secretase inhibition assay. ChEMBL. No reference
IC50 (binding) = 870 nM BindingDB_Patents: Inhibition Assay. Beta-Secretase inhibition assay. ChEMBL. No reference
IC50 (binding) = 870 nM BindingDB_Patents: Inhibition Assay. Inhibition assay using human BACE-1. ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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