Detailed information for compound 2073713

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 442.553 | Formula: C27H30N4O2
  • H donors: 2 H acceptors: 2 LogP: 4.8 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCCN(CC1)c1ccc(cc1)C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)C
  • InChi: 1S/C27H30N4O2/c1-20-7-5-8-22(19-20)28-27(33)24-9-3-4-10-25(24)29-26(32)21-11-13-23(14-12-21)31-16-6-15-30(2)17-18-31/h3-5,7-14,19H,6,15-18H2,1-2H3,(H,28,33)(H,29,32)
  • InChiKey: BYDITOSFLBIUDN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0014 0.01 0.008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0062 0.1094 0.1076
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0108 0.2064 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.1245 0.1227
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0014 0.01 0.008
Onchocerca volvulus 0.0018 0.0194 0.0226
Echinococcus granulosus microtubule associated protein 2 0.0464 0.9427 0.9427
Echinococcus granulosus sodium and chloride dependent glycine 0.0492 1 1
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0096 0.18 0.18
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0014 0.01 0.008
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0023 0.0291 0.0291
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0096 0.18 0.18
Onchocerca volvulus 0.015 0.2928 0.6805
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.0291 0.0271
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0014 0.01 0.008
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0096 0.18 0.18
Schistosoma mansoni cellular tumor antigen P53 0.0031 0.0468 0.0448
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0014 0.01 0.01
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0096 0.18 0.1783
Echinococcus granulosus beta LACTamase domain containing family member 0.0023 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.0096 0.18 0.18
Onchocerca volvulus Huntingtin homolog 0.0082 0.1525 0.3428
Mycobacterium ulcerans glutaminase 0.0357 0.7213 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0014 0.01 0.01
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0014 0.01 0.01
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0062 0.1094 0.1076
Loa Loa (eye worm) steroid hormone receptor 0.0014 0.01 0.01
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.1245 0.1227
Trichomonas vaginalis set domain proteins, putative 0.015 0.2928 0.3809
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0024 0.0314 0.0033
Echinococcus multilocularis musashi 0.0018 0.0194 0.0194
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0368 0.7431 0.7431
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0492 1 1
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0026 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0023 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.0014 0.01 0.01
Mycobacterium leprae Probable lipase LipE 0.0023 0.0291 0.5
Loa Loa (eye worm) hypothetical protein 0.0014 0.01 0.01
Toxoplasma gondii hypothetical protein 0.0096 0.18 0.8709
Onchocerca volvulus 0.0096 0.18 0.4091
Brugia malayi Pre-SET motif family protein 0.0019 0.0211 0.0191
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0211 0.019
Loa Loa (eye worm) hypothetical protein 0.0082 0.1525 0.1525
Echinococcus multilocularis microtubule associated protein 2 0.0464 0.9427 0.9427
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0014 0.01 0.008
Loa Loa (eye worm) beta-lactamase 0.0023 0.0291 0.0291
Echinococcus granulosus intermediate filament protein 0.0018 0.0194 0.0194
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0062 0.1094 0.1094
Schistosoma mansoni sodium/chloride dependent transporter 0.0096 0.18 0.1783
Echinococcus granulosus vesicular acetylcholine transporter 0.0214 0.4256 0.4256
Echinococcus granulosus lamin 0.0018 0.0194 0.0194
Brugia malayi Intermediate filament tail domain containing protein 0.0018 0.0194 0.0175
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0014 0.01 0.008
Toxoplasma gondii ABC1 family protein 0.0023 0.0291 0.1325
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0096 0.18 0.1783
Schistosoma mansoni thyroid hormone receptor 0.0014 0.01 0.008
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0014 0.01 0.008
Loa Loa (eye worm) hypothetical protein 0.0096 0.18 0.18
Loa Loa (eye worm) serotonin transporter b 0.0096 0.18 0.18
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0022 0.0264 0.0245
Loa Loa (eye worm) hypothetical protein 0.0023 0.0291 0.0291
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0146 0.2838 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0062 0.1094 0.1094
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.01 0.01
Plasmodium vivax amine transporter, putative 0.0096 0.18 0.8577
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0046 0.077 0.0751
Onchocerca volvulus 0.0023 0.0291 0.046
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0069 0.1245 0.1245
Brugia malayi Steroid receptor seven-up type 2 0.0014 0.01 0.008
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0398 0.0378
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0014 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0014 0.01 0.01
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0062 0.1094 0.1094
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0096 0.18 0.5
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0026 0.0349 0.033
Brugia malayi Latrophilin receptor protein 2 0.0022 0.0264 0.0245
Loa Loa (eye worm) hypothetical protein 0.0022 0.0264 0.0264
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0068 0.1226 0.1226
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0014 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0014 0.01 0.01
Brugia malayi vesicular acetylcholine transporter unc-17 0.0214 0.4256 0.4244
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0018 0.0196 0.0196
Schistosoma mansoni RAR-like nuclear receptor 0.0014 0.01 0.008
Schistosoma mansoni intermediate filament proteins 0.0018 0.0194 0.0174
Brugia malayi photoreceptor-specific nuclear receptor 0.0014 0.01 0.008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0211 0.0211
Echinococcus granulosus GPCR family 2 0.0022 0.0264 0.0264
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0014 0.01 0.008
Echinococcus multilocularis lamin 0.0018 0.0194 0.0194
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0096 0.18 0.1784
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0096 0.18 0.1784
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0062 0.1094 0.1076
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.01 0.008
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0398 0.0378
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0022 0.0264 0.0264
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0023 0.0291 0.0272
Loa Loa (eye worm) glutaminase 0.0357 0.7213 0.7213
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0096 0.18 0.8709
Schistosoma mansoni thyroid hormone receptor 0.0014 0.01 0.008
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0022 0.0264 0.0264
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0014 0.01 0.008
Brugia malayi steroid hormone receptor 0.0014 0.01 0.008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0014 0.01 0.01
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0096 0.18 0.18
Echinococcus multilocularis sodium and chloride dependent glycine 0.0492 1 1
Schistosoma mansoni lamin 0.0018 0.0194 0.0174
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0062 0.1094 0.1094
Echinococcus multilocularis GPCR, family 2 0.0022 0.0264 0.0264
Brugia malayi Melibiase family protein 0.0046 0.077 0.0751
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0014 0.01 0.01
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0014 0.01 0.008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0014 0.01 0.008
Schistosoma mansoni steroid hormone receptor ad4bp 0.0014 0.01 0.008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0279 0.0279
Loa Loa (eye worm) hypothetical protein 0.0018 0.0187 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0014 0.01 0.008
Loa Loa (eye worm) hypothetical protein 0.0014 0.01 0.01
Echinococcus multilocularis tumor protein p63 0.0214 0.4254 0.4254
Schistosoma mansoni sodium/chloride dependent transporter 0.0492 1 1
Echinococcus multilocularis lamin dm0 0.0018 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0492 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0211 0.019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.01 0.01
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0014 0.01 0.008
Plasmodium falciparum amino acid transporter, putative 0.0096 0.18 0.8107
Brugia malayi Pre-SET motif family protein 0.0132 0.2551 0.2536
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.001 0.002 0.002
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0014 0.01 0.008
Schistosoma mansoni microtubule-associated protein tau 0.0464 0.9427 0.9426
Onchocerca volvulus 0.0096 0.18 0.4091
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0014 0.01 0.01
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0096 0.18 0.1783
Brugia malayi beta-lactamase 0.0023 0.0291 0.0272
Schistosoma mansoni hypothetical protein 0.0238 0.4738 0.4727
Toxoplasma gondii cathepsin CPC1 0.0108 0.2064 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.01 0.01
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0096 0.18 0.18
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0014 0.01 0.008
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0108 0.2064 1
Loa Loa (eye worm) hypothetical protein 0.0492 1 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.1245 0.1227
Loa Loa (eye worm) hypothetical protein 0.0082 0.1525 0.1525
Schistosoma mansoni sodium-dependent amino acid transporter 0.0096 0.18 0.1783
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0214 0.4256 0.4256
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0026 0.0349 0.0349
Echinococcus multilocularis geminin 0.0238 0.4738 0.4738
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0014 0.01 0.008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0019 0.0211 0.019
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0096 0.18 0.18
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0014 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0023 0.0291 0.0291
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0014 0.01 0.01
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.01 0.008
Echinococcus granulosus sodium and chloride dependent glycine 0.0492 1 1
Onchocerca volvulus 0.0096 0.18 0.4091
Echinococcus granulosus FTZ F1 alpha 0.0014 0.01 0.01
Schistosoma mansoni hypothetical protein 0.0022 0.0264 0.0244
Echinococcus multilocularis FTZ F1 alpha 0.0014 0.01 0.01
Schistosoma mansoni vesicular acetylcholine transporter 0.0214 0.4256 0.4244
Schistosoma mansoni hypothetical protein 0.0022 0.0264 0.0244
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0069 0.1245 0.1245
Echinococcus granulosus geminin 0.0238 0.4738 0.4738
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0108 0.2064 1
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0291 0.5
Loa Loa (eye worm) hypothetical protein 0.0096 0.18 0.18
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0096 0.18 0.8709
Brugia malayi nuclear hormone receptor 0.0014 0.01 0.008
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0014 0.01 0.01
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0096 0.18 0.1784
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0014 0.01 0.01
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0062 0.1094 0.1076
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0014 0.01 0.01
Loa Loa (eye worm) solute carrier family 6 member 4 0.0096 0.18 0.18
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0046 0.077 0.0691
Brugia malayi ecdysteroid receptor 0.0014 0.01 0.008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0014 0.01 0.008
Loa Loa (eye worm) hypothetical protein 0.0014 0.01 0.01
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0291 0.5
Schistosoma mansoni coup transcription factor 0.0014 0.01 0.008
Schistosoma mansoni sodium/chloride dependent transporter 0.0492 1 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0291 0.0291
Plasmodium vivax hypothetical protein, conserved 0.0096 0.18 0.8577
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0214 0.4256 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0096 0.18 0.18
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0069 0.1245 0.1245
Echinococcus multilocularis beta LACTamase domain containing family member 0.0023 0.0291 0.0291
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.1245 0.1227
Loa Loa (eye worm) hypothetical protein 0.0096 0.18 0.18
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0022 0.0264 0.0264
Toxoplasma gondii hypothetical protein 0.0096 0.18 0.8709
Toxoplasma gondii melibiase subfamily protein 0.0069 0.1245 0.5992
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0096 0.18 0.1783
Loa Loa (eye worm) hypothetical protein 0.0023 0.0291 0.0291
Schistosoma mansoni retinoic acid receptor RXR 0.0014 0.01 0.008
Loa Loa (eye worm) hypothetical protein 0.0068 0.1226 0.1226
Toxoplasma gondii preprocathepsin c precursor, putative 0.0108 0.2064 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0468 0.0468
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0018 0.0194 0.0194
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0211 0.0211
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.0291 0.0271
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0068 0.1226 0.1209
Echinococcus granulosus serotonin transporter 0.0096 0.18 0.18
Schistosoma mansoni glutaminase 0.0357 0.7213 0.7207
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0096 0.18 0.1783
Loa Loa (eye worm) hypothetical protein 0.0046 0.077 0.077
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0014 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0096 0.18 0.18
Loa Loa (eye worm) hypothetical protein 0.0023 0.0291 0.0291
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0014 0.01 0.01
Brugia malayi Calcitonin receptor-like protein seb-1 0.0068 0.1226 0.1209
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0096 0.18 0.1783
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0014 0.01 0.008
Echinococcus multilocularis ecdysone induced protein 78C 0.0014 0.01 0.01
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0096 0.18 0.1783
Loa Loa (eye worm) hypothetical protein 0.0096 0.18 0.18
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0022 0.0264 0.0264
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0062 0.1094 0.1094
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0096 0.18 0.18
Brugia malayi glutaminase DH11.1 0.0357 0.7213 0.7208
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0041 0.0671 0.2482
Onchocerca volvulus 0.0018 0.0194 0.0226
Echinococcus granulosus lamin dm0 0.0018 0.0194 0.0194
Brugia malayi intermediate filament protein 0.0018 0.0194 0.0175
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0019 0.0211 0.093
Brugia malayi beta-lactamase family protein 0.0023 0.0291 0.0272
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0096 0.18 0.1783
Brugia malayi hypothetical protein 0.0096 0.18 0.1784
Loa Loa (eye worm) intermediate filament protein 0.0018 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0018 0.0194 0.0194
Schistosoma mansoni hypothetical protein 0.0238 0.4738 0.4727
Schistosoma mansoni hypothetical protein 0.0046 0.0781 0.0762
Echinococcus granulosus tm gpcr rhodopsin 0.0368 0.7431 0.7431
Brugia malayi hypothetical protein 0.0082 0.1525 0.1508
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0108 0.2064 1
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0291 0.5
Echinococcus granulosus tumor protein p63 0.0214 0.4254 0.4254
Echinococcus multilocularis sodium and chloride dependent glycine 0.0492 1 1
Brugia malayi nuclear receptor NHR-88 0.0014 0.01 0.008
Onchocerca volvulus 0.0023 0.0291 0.046
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0211 0.019
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0046 0.077 0.0751
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.01 0.01
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0096 0.18 0.1784
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0096 0.18 0.8709
Echinococcus multilocularis vesicular acetylcholine transporter 0.0214 0.4256 0.4256
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0132 0.2551 0.2551
Onchocerca volvulus 0.0096 0.18 0.4091
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0067 0.1212 0.133
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0291 0.0436
Leishmania major hypothetical protein, conserved 0.0023 0.0291 0.5
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0014 0.01 0.01
Echinococcus multilocularis serotonin transporter 0.0096 0.18 0.18
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.01 0.01
Treponema pallidum sodium- and chloride- dependent transporter 0.0096 0.18 0.5
Onchocerca volvulus Huntingtin homolog 0.0082 0.1525 0.3428
Echinococcus granulosus ecdysone induced protein 78C 0.0014 0.01 0.01
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0096 0.18 0.18
Schistosoma mansoni lamin 0.0018 0.0194 0.0174
Loa Loa (eye worm) hypothetical protein 0.0046 0.0781 0.0781
Loa Loa (eye worm) norepinephrine transporter 0.0096 0.18 0.18
Onchocerca volvulus 0.0019 0.0211 0.0266
Brugia malayi beta-lactamase family protein 0.0023 0.0291 0.0272
Schistosoma mansoni hypothetical protein 0.0022 0.0264 0.0244
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0291 0.5
Plasmodium falciparum transporter, putative 0.0096 0.18 0.8107
Toxoplasma gondii cathepsin CPC2 0.0041 0.0671 0.3181
Brugia malayi latrophilin 2 splice variant baaae 0.0046 0.0781 0.0763
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0096 0.18 0.1783
Schistosoma mansoni nuclear hormone receptor 0.0014 0.01 0.008
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0026 0.0349 0.0349
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0108 0.2064 1
Onchocerca volvulus 0.0023 0.0291 0.046
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0108 0.2064 0.2047
Schistosoma mansoni hypothetical protein 0.0022 0.0264 0.0244
Loa Loa (eye worm) hypothetical protein 0.0014 0.01 0.01
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0024 0.0314 0.0033
Loa Loa (eye worm) latrophilin receptor protein 2 0.0022 0.0264 0.0264
Onchocerca volvulus 0.0031 0.0468 0.0885
Loa Loa (eye worm) glutaminase 2 0.0357 0.7213 0.7213
Trichomonas vaginalis glutaminase, putative 0.0357 0.7213 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0014 0.01 0.01
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0019 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0096 0.18 0.18

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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