Detailed information for compound 336584

Basic information

Technical information
  • TDR Targets ID: 336584
  • Name: 1-propan-2-ylimidazo[4,5-c]quinolin-4-amine
  • MW: 226.277 | Formula: C13H14N4
  • H donors: 1 H acceptors: 2 LogP: 2.06 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1nc2ccccc2c2c1ncn2C(C)C
  • InChi: 1S/C13H14N4/c1-8(2)17-7-15-11-12(17)9-5-3-4-6-10(9)16-13(11)14/h3-8H,1-2H3,(H2,14,16)
  • InChiKey: MZHCMKLGOQGXGC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-isopropylimidazo[4,5-c]quinolin-4-amine
  • 1-isopropyl-4-imidazo[4,5-c]quinolinamine
  • (1-isopropylimidazo[4,5-c]quinolin-4-yl)amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii aldose reductase, putative 0.0107 0.0232 0.4131
Brugia malayi Stress-activated protein kinase jnk-1 0.0231 0.0573 0.0573
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0044 0.0057 0.0057
Brugia malayi Tachykinin-like peptides receptor 99D 0.0164 0.0388 0.0388
Onchocerca volvulus 0.0042 0.0053 0.084
Schistosoma mansoni biogenic amine receptor 0.0164 0.0388 0.0388
Brugia malayi intermediate filament protein 0.0033 0.0026 0.0026
Onchocerca volvulus 0.0164 0.0388 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0042 0.0053 0.0053
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0044 0.0057 0.0057
Brugia malayi Cathepsin L-like precursor 0.0152 0.0356 0.0356
Echinococcus multilocularis voltage gated potassium channel subunit 0.0031 0.0022 0.0022
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0164 0.0388 0.0388
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Schistosoma mansoni adenoreceptor 0.0164 0.0388 0.0388
Schistosoma mansoni pcd6 interacting protein-related 0.0093 0.0192 0.0192
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0114 0.025 0.1447
Trypanosoma cruzi cysteine peptidase, putative 0.0045 0.0059 0.0237
Leishmania major prostaglandin f synthase, putative 0.0107 0.0232 0.4131
Echinococcus granulosus g protein coupled receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.3655 1 1
Brugia malayi prostaglandin transporter 0.0047 0.0067 0.0067
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0031 0.0022 0.0022
Echinococcus granulosus mitogen activated protein kinase 3 0.0114 0.025 0.025
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0093 0.0192 0.5074
Onchocerca volvulus 0.0093 0.0192 0.4627
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0044 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0152 0.0356 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0042 0.0053 0.0195
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0176 0.3024
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Echinococcus granulosus alpha 1A adrenergic receptor 0.0164 0.0388 0.0388
Onchocerca volvulus 0.0164 0.0388 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0044 0.0057 0.0057
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0026 0.0026
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0047 0.0067 0.0067
Echinococcus multilocularis cathepsin b 0.0603 0.1597 0.1597
Mycobacterium ulcerans oxidoreductase 0.0107 0.0232 1
Leishmania major cathepsin L-like protease 0.0152 0.0356 0.6573
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0057 0.0057
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0216 0.053 1
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Loa Loa (eye worm) protein tyrosine phosphatase 0.0093 0.0192 0.0192
Brugia malayi RE15519p 0.0164 0.0388 0.0388
Giardia lamblia Protein tyrosine phosphatase 0.0093 0.0192 0.2905
Echinococcus granulosus tachykinin peptides receptor 99D 0.0164 0.0388 0.0388
Trichomonas vaginalis aldo-keto reductase, putative 0.0107 0.0232 0.4131
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0044 0.0057 0.0057
Onchocerca volvulus Cathepsin L homolog 0.0042 0.0053 0.084
Echinococcus granulosus peptide allatostatin:somatostatin 0.0164 0.0388 0.0388
Echinococcus multilocularis aldo keto reductase 0.0107 0.0232 0.0232
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0042 0.0053 0.0921
Onchocerca volvulus 0.0164 0.0388 1
Toxoplasma gondii preprocathepsin c precursor, putative 0.0042 0.0053 0.0605
Brugia malayi G protein-coupled receptor 0.0164 0.0388 0.0388
Brugia malayi Papain family cysteine protease containing protein 0.0087 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Brugia malayi ecdysteroid receptor 0.0044 0.0057 0.0057
Echinococcus granulosus geminin 0.0205 0.05 0.05
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0045 0.0059 0.0059
Loa Loa (eye worm) melatonin receptor type 1A 0.0164 0.0388 0.0388
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Schistosoma mansoni amine GPCR 0.0164 0.0388 0.0388
Echinococcus granulosus lamin dm0 0.0033 0.0026 0.0026
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0047 0.0067 0.0067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0356 0.6573
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0164 0.0388 0.0388
Trichomonas vaginalis aldo-keto reductase, putative 0.0107 0.0232 0.4131
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0042 0.0053 0.0605
Onchocerca volvulus 0.0152 0.0356 0.912
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Entamoeba histolytica hypothetical protein 0.0043 0.0056 0.1018
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0164 0.0388 0.0388
Onchocerca volvulus 0.0093 0.0192 0.4627
Schistosoma mansoni neuropeptide receptor 0.0164 0.0388 0.0388
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0042 0.0053 0.0053
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0164 0.0388 0.0388
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0164 0.0388 0.0388
Echinococcus multilocularis neuropeptide FF receptor 2 0.0164 0.0388 0.0388
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0107 0.0232 0.0232
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0045 0.0059 0.0059
Echinococcus multilocularis geminin 0.0205 0.05 0.05
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Brugia malayi GnHR receptor homolog 0.0164 0.0388 0.0388
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0388 0.0388
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0093 0.0192 0.0192
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0093 0.0192 0.0192
Schistosoma mansoni histamine h1 receptor 0.0164 0.0388 0.0388
Plasmodium falciparum cysteine proteinase falcipain 3 0.0152 0.0356 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Onchocerca volvulus 0.0152 0.0356 0.912
Echinococcus multilocularis g protein coupled receptor 0.0164 0.0388 0.0388
Schistosoma mansoni hypothetical protein 0.0205 0.05 0.05
Echinococcus granulosus cathepsin b 0.0603 0.1597 0.1597
Brugia malayi cathepsin B-like cysteine proteinase 0.0603 0.1597 0.1597
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.0057
Echinococcus multilocularis G-protein coupled receptor, putative 0.0164 0.0388 0.0388
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Echinococcus granulosus neuropeptide receptor 0.0164 0.0388 0.0388
Echinococcus multilocularis transfer RNA-Lys 0.0041 0.0049 0.0049
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0042 0.0053 0.0921
Trypanosoma brucei prostaglandin f synthase 0.0107 0.0232 0.4131
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0164 0.0388 0.0388
Entamoeba histolytica hypothetical protein 0.0043 0.0056 0.1018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Schistosoma mansoni opsin-like receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0047 0.0067 0.0067
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0057 0.0057
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0093 0.0192 0.1076
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Echinococcus granulosus lamin 0.0033 0.0026 0.0026
Echinococcus multilocularis mitogen activated protein kinase 3 0.0114 0.025 0.025
Echinococcus multilocularis lamin dm0 0.0033 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Schistosoma mansoni protein tyrosine phosphatase 0.0093 0.0192 0.0192
Onchocerca volvulus 0.0108 0.0233 0.5763
Echinococcus multilocularis cathepsin b 0.0603 0.1597 0.1597
Onchocerca volvulus 0.0164 0.0388 1
Onchocerca volvulus 0.0164 0.0388 1
Schistosoma mansoni opsin-like receptor 0.0164 0.0388 0.0388
Brugia malayi Cathepsin L-like precursor 0.0152 0.0356 0.0356
Schistosoma mansoni neuropeptide receptor 0.0164 0.0388 0.0388
Brugia malayi fibroinase precursor 0.0042 0.0053 0.0053
Echinococcus granulosus G protein coupled receptor 139 0.0164 0.0388 0.0388
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0107 0.0232 0.0232
Brugia malayi Cathepsin L-like cysteine proteinase 0.0108 0.0233 0.0233
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0093 0.0192 0.0192
Echinococcus multilocularis neuropeptide s receptor 0.0164 0.0388 0.0388
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.3655 1 1
Echinococcus granulosus somatostatin receptor 0.0164 0.0388 0.0388
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Entamoeba histolytica cysteine protease, putative 0.0152 0.0356 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0053 0.0605
Echinococcus granulosus 7TM GPCR rhodopsin 0.0164 0.0388 0.0388
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0042 0.0053 0.0053
Schistosoma mansoni intermediate filament proteins 0.0033 0.0026 0.0026
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0044 0.0057 0.0057
Brugia malayi cathepsin Z-like cysteine proteinase 0.0042 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0087 0.0176 0.3024
Onchocerca volvulus 0.0152 0.0356 0.912
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0093 0.0192 0.0192
Plasmodium vivax vivapain-2 0.0152 0.0356 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0356 0.6573
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0164 0.0388 0.0388
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0042 0.0053 0.0921
Echinococcus granulosus cathepsin b 0.0603 0.1597 0.1597
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0057 0.0057
Echinococcus multilocularis aldo keto reductase 0.0107 0.0232 0.0232
Echinococcus multilocularis sex peptide receptor 0.0164 0.0388 0.0388
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0107 0.0232 0.4131
Entamoeba histolytica protein kinase, putative 0.0099 0.021 0.5619
Loa Loa (eye worm) hypothetical protein 0.0603 0.1597 0.1597
Onchocerca volvulus 0.0047 0.0067 0.1222
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0164 0.0388 0.0388
Onchocerca volvulus Neuropeptide F receptor homolog 0.0164 0.0388 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0152 0.0356 0.6573
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0042 0.0053 0.0605
Trypanosoma cruzi cysteine peptidase, putative 0.0152 0.0356 0.2121
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0042 0.0053 0.0605
Echinococcus multilocularis 0.0093 0.0192 0.0192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0356 0.6573
Brugia malayi sodium-independent organic anion transporter family protein 0.0047 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Trichomonas vaginalis pten, drome, putative 0.0093 0.0192 0.3335
Entamoeba histolytica cysteine proteinase, putative 0.0152 0.0356 1
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Entamoeba histolytica protein kinase, putative 0.0099 0.021 0.5619
Trypanosoma cruzi cysteine protease, putative 0.0087 0.0176 0.0976
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Onchocerca volvulus 0.0093 0.0192 0.4627
Plasmodium falciparum serine repeat antigen 6 0.0042 0.0053 0.0921
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Echinococcus granulosus cathepsin L 0.0042 0.0053 0.0053
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0093 0.0192 0.1076
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Schistosoma mansoni hypothetical protein 0.0043 0.0056 0.0056
Schistosoma mansoni cathepsin C 0.0042 0.0053 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0044 0.0057 0.0057
Echinococcus multilocularis neuropeptide Y receptor 0.0164 0.0388 0.0388
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0044 0.0057 0.0057
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0031 0.0022 0.0022
Onchocerca volvulus 0.0093 0.0192 0.4627
Onchocerca volvulus 0.0093 0.0192 0.4627
Onchocerca volvulus 0.0164 0.0388 1
Echinococcus granulosus protein tyrosine phosphatase n9 0.0093 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0042 0.0053 0.0605
Brugia malayi Papain family cysteine protease containing protein 0.0042 0.0053 0.0053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0152 0.0356 0.6573
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0093 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Onchocerca volvulus 0.0093 0.0192 0.4627
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0042 0.0053 0.0921
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0042 0.0053 0.0605
Onchocerca volvulus 0.0093 0.0192 0.4627
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0044 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.0057
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0093 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0164 0.0388 0.0388
Echinococcus multilocularis G protein coupled receptor 139 0.0164 0.0388 0.0388
Echinococcus multilocularis neuropeptide receptor 0.0164 0.0388 0.0388
Plasmodium vivax unspecified product 0.0045 0.0059 0.1118
Brugia malayi Serotonin receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0053 0.0605
Trichomonas vaginalis aldo/keto reductase, putative 0.0107 0.0232 0.4131
Brugia malayi hypothetical protein 0.0093 0.0192 0.0192
Echinococcus multilocularis neuropeptide receptor 0.0164 0.0388 0.0388
Schistosoma mansoni pol-related 0.0107 0.0232 0.0232
Onchocerca volvulus Cathepsin F homolog 0.0152 0.0356 0.912
Brugia malayi hypoxia-induced factor 1 0.017 0.0406 0.0406
Brugia malayi cathepsin F-like cysteine proteinase 0.0042 0.0053 0.0053
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Giardia lamblia Cathepsin B precursor 0.0216 0.053 1
Entamoeba histolytica cysteine proteinase, putative 0.0108 0.0233 0.6319
Leishmania major tyrosine specific protein phosphatase, putative 0.0093 0.0192 0.3335
Loa Loa (eye worm) hypothetical protein 0.0108 0.0233 0.0233
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0044 0.0057 0.0057
Brugia malayi Papain family cysteine protease containing protein 0.0042 0.0053 0.0053
Plasmodium falciparum cysteine proteinase falcipain 1 0.0087 0.0176 0.4602
Schistosoma mansoni aldo-keto reductase 0.0107 0.0232 0.0232
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0093 0.0192 0.0192
Giardia lamblia Aldose reductase 0.0107 0.0232 0.3753
Trypanosoma brucei cysteine peptidase C (CPC) 0.0216 0.053 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0093 0.0192 0.0192
Schistosoma mansoni organic anion transporter 0.0047 0.0067 0.0067
Onchocerca volvulus 0.0093 0.0192 0.4627
Echinococcus granulosus cathepsin l1 0.0108 0.0233 0.0233
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0152 0.0356 0.6573
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0164 0.0388 0.0388
Plasmodium vivax vivapain-2 0.0152 0.0356 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Schistosoma mansoni opsin-like receptor 0.0164 0.0388 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0176 0.3024
Echinococcus granulosus voltage gated potassium channel subunit 0.0031 0.0022 0.0022
Onchocerca volvulus 0.0107 0.0232 0.5732
Schistosoma mansoni lamin 0.0033 0.0026 0.0026
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.3655 1 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Echinococcus granulosus ecdysone induced protein 78C 0.0044 0.0057 0.0057
Entamoeba histolytica aldose reductase, putative 0.0107 0.0232 0.6286
Brugia malayi follicle stimulating hormone receptor 0.0675 0.1794 0.1794
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Loa Loa (eye worm) steroid hormone receptor 0.0044 0.0057 0.0057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0356 0.6573
Brugia malayi Cathepsin L-like precursor 0.0152 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Plasmodium falciparum serine repeat antigen 8 0.0042 0.0053 0.0921
Trypanosoma cruzi cruzipain precursor, putative 0.0045 0.0059 0.0237
Loa Loa (eye worm) hypothetical protein 0.0042 0.0053 0.0053
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Leishmania major cathepsin L-like protease 0.0152 0.0356 0.6573
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0107 0.0232 0.0232
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0164 0.0388 0.0388
Echinococcus multilocularis g protein coupled receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) oxidoreductase 0.0107 0.0232 0.0232
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0164 0.0388 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0152 0.0356 0.6573
Schistosoma mansoni biogenic amine receptor 0.0164 0.0388 0.0388
Echinococcus granulosus c-Jun N-terminal kinases 0.0231 0.0573 0.0573
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0093 0.0192 0.0192
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0164 0.0388 0.0388
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0354 0.0911 0.0911
Toxoplasma gondii cathepsin CPC2 0.0042 0.0053 0.0605
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0164 0.0388 0.0388
Trypanosoma brucei aldo-keto reductase, putative 0.0107 0.0232 0.4131
Echinococcus multilocularis somatostatin receptor 0.0164 0.0388 0.0388
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0093 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0053 0.0605
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.0573 0.0573
Echinococcus multilocularis ecdysone induced protein 78C 0.0044 0.0057 0.0057
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0164 0.0388 0.0388
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0044 0.0057 0.0057
Echinococcus granulosus aldo keto reductase 0.0107 0.0232 0.0232
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0114 0.025 0.4482
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Echinococcus granulosus fmrfamide receptor 0.0164 0.0388 0.0388
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0093 0.0192 0.0192
Onchocerca volvulus 0.0093 0.0192 0.4627
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0044 0.0057 0.0057
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Loa Loa (eye worm) hypothetical protein 0.0045 0.0059 0.0059
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Brugia malayi Protein-tyrosine phosphatase 1 0.0093 0.0192 0.0192
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0603 0.1597 0.1597
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0053 0.0605
Onchocerca volvulus 0.0093 0.0192 0.4627
Echinococcus granulosus hypothetical protein 0.0107 0.0232 0.0232
Onchocerca volvulus Putative organic anion transporter 0.0047 0.0067 0.1222
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) IRE protein kinase 0.0099 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Entamoeba histolytica cysteine proteinase 1, putative 0.0087 0.0176 0.4602
Onchocerca volvulus 0.0093 0.0192 0.4627
Brugia malayi putative neuropeptide receptor 0.0164 0.0388 0.0388
Onchocerca volvulus Bile acid receptor homolog 0.0044 0.0057 0.0945
Echinococcus granulosus tm gpcr rhodopsin 0.0164 0.0388 0.0388
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0107 0.0232 0.0232
Onchocerca volvulus 0.0152 0.0356 0.912
Mycobacterium ulcerans putative regulatory protein 0.0041 0.0049 0.1267
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Onchocerca volvulus Cathepsin L homolog 0.0152 0.0356 0.912
Echinococcus multilocularis allatostatin A receptor 0.0164 0.0388 0.0388
Echinococcus granulosus neuropeptide Y receptor 0.0164 0.0388 0.0388
Brugia malayi Cathepsin L-like precursor 0.0108 0.0233 0.0233
Trichomonas vaginalis aldo/keto reductase, putative 0.0107 0.0232 0.4131
Loa Loa (eye worm) cysteine protease 0.0152 0.0356 0.0356
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0079 0.0079
Onchocerca volvulus 0.0047 0.0067 0.1222
Schistosoma mansoni organic anion transporter 0.0047 0.0067 0.0067
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0388 0.0388
Plasmodium vivax unspecified product 0.0042 0.0053 0.0921
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0216 0.053 0.053
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0164 0.0388 0.0388
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0107 0.0232 0.0232
Echinococcus granulosus cathepsin L 0.0087 0.0176 0.0176
Onchocerca volvulus 0.0107 0.0232 0.5732
Onchocerca volvulus 0.0047 0.0067 0.1222
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Schistosoma mansoni aryl hydrocarbon receptor 0.0055 0.0088 0.0088
Mycobacterium leprae Conserved hypothetical protein 0.0076 0.0146 0.5922
Brugia malayi hypothetical protein 0.0185 0.0445 0.0445
Brugia malayi Melatonin receptor type 1A 0.0164 0.0388 0.0388
Entamoeba histolytica cysteine proteinase, putative 0.0152 0.0356 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0388 0.0388
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0356 0.6573
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Leishmania major cathepsin L-like protease 0.0152 0.0356 0.6573
Schistosoma mansoni cathepsin B (C01 family) 0.0042 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0047 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0107 0.0232 0.0232
Echinococcus granulosus biogenic amine 5HT receptor 0.0164 0.0388 0.0388
Schistosoma mansoni protein tyrosine phosphatase 0.0093 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) G-protein coupled receptor 0.0164 0.0388 0.0388
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0356 0.6573
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0603 0.1597 0.1597
Echinococcus multilocularis serotonin receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0047 0.0067 0.0067
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0044 0.0057 0.0057
Echinococcus granulosus cathepsin L cysteine proteinase 0.0152 0.0356 0.0356
Leishmania major cathepsin L-like protease 0.0152 0.0356 0.6573
Plasmodium falciparum serine repeat antigen 2 0.0042 0.0053 0.0921
Echinococcus granulosus hypothetical protein 0.0164 0.0388 0.0388
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0231 0.0573 0.0573
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0044 0.0057 0.0057
Onchocerca volvulus 0.0093 0.0192 0.4627
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.0057
Onchocerca volvulus 0.0033 0.0026 0.011
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0047 0.0067 0.0067
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0087 0.0176 0.0176
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0152 0.0356 0.6573
Leishmania major cathepsin L-like protease 0.0152 0.0356 0.6573
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0093 0.0192 0.0192
Trypanosoma cruzi cysteine proteinase, putative 0.0087 0.0176 0.0976
Onchocerca volvulus Putative organic anion transporter 0.0047 0.0067 0.1222
Echinococcus granulosus dro:myosuppressin receptor 0.0164 0.0388 0.0388
Brugia malayi Serotonin receptor 0.0164 0.0388 0.0388
Onchocerca volvulus 0.0093 0.0192 0.4627
Echinococcus granulosus tm gpcr rhodopsin 0.0164 0.0388 0.0388
Brugia malayi neuropeptide F receptor 0.0164 0.0388 0.0388
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0093 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0152 0.0356 0.6573
Schistosoma mansoni amine GPCR 0.0164 0.0388 0.0388
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Onchocerca volvulus 0.0093 0.0192 0.4627
Schistosoma mansoni biogenic amine (5HT) receptor 0.0164 0.0388 0.0388
Schistosoma mansoni neuropeptide receptor 0.0164 0.0388 0.0388
Plasmodium vivax serine-repeat antigen (SERA) 0.0042 0.0053 0.0921
Brugia malayi Cytochrome P450 family protein 0.0026 0.0007 0.0007
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0042 0.0053 0.0921
Onchocerca volvulus 0.0164 0.0388 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0044 0.0057 0.0057
Schistosoma mansoni retinoic acid receptor RXR 0.0044 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0047 0.0067 0.0067
Brugia malayi hypothetical protein 0.0093 0.0192 0.0192
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0042 0.0053 0.0053
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0044 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0107 0.0232 0.0232
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0603 0.1597 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0042 0.0053 0.0605
Echinococcus granulosus neuropeptide receptor 0.0164 0.0388 0.0388
Schistosoma mansoni protein tyrosine phosphatase 0.0093 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.025 0.4482
Brugia malayi Protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Schistosoma mansoni hypothetical protein 0.0062 0.0108 0.0108
Onchocerca volvulus 0.0164 0.0388 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0107 0.0232 0.0232
Trypanosoma cruzi cysteine peptidase, putative 0.0152 0.0356 0.2121
Onchocerca volvulus 4.1 G protein, putative homolog 0.0093 0.0192 0.4627
Brugia malayi Dopamine receptor 0.0164 0.0388 0.0388
Plasmodium falciparum serine repeat antigen 7 0.0042 0.0053 0.0921
Echinococcus multilocularis aldo keto reductase 0.0107 0.0232 0.0232
Echinococcus granulosus neuropeptide receptor A26 0.0164 0.0388 0.0388
Echinococcus granulosus Solute carrier family 22 5 0.1125 0.3034 0.3034
Echinococcus granulosus intermediate filament protein 0.0033 0.0026 0.0026
Echinococcus multilocularis cathepsin L 0.0087 0.0176 0.0176
Trichomonas vaginalis aldo-keto reductase, putative 0.0107 0.0232 0.4131
Echinococcus granulosus serine:threonine protein kinase:endoribonuclease 0.0099 0.021 0.021
Schistosoma mansoni steroid hormone receptor ad4bp 0.0044 0.0057 0.0057
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0026 0.0026
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0164 0.0388 0.0388
Brugia malayi Ribonuclease 2-5A family protein 0.0099 0.021 0.021
Leishmania major cathepsin L-like protease 0.0152 0.0356 0.6573
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0114 0.025 0.1447
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0093 0.0192 0.3335
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0044 0.0057 0.0057
Echinococcus multilocularis cathepsin L cysteine protease 0.0152 0.0356 0.0356
Trypanosoma cruzi cruzipain precursor, putative 0.0152 0.0356 0.2121
Echinococcus multilocularis serine:threonine protein kinase:endoribonuclease 0.0099 0.021 0.021
Echinococcus granulosus neuropeptide Y receptor 0.0164 0.0388 0.0388
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0042 0.0053 0.0921
Echinococcus multilocularis hypothetical protein 0.0093 0.0192 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0053 0.0605
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0093 0.0192 0.0192
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0107 0.0232 0.0232
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0164 0.0388 0.0388
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0093 0.0192 0.0192
Schistosoma mansoni myosin xvIII 0.0164 0.0388 0.0388
Echinococcus granulosus sex peptide receptor 0.0164 0.0388 0.0388
Schistosoma mansoni hypothetical protein 0.0164 0.0388 0.0388
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0057 0.0057
Schistosoma mansoni aldo-keto reductase 0.0107 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0164 0.0388 0.0388
Brugia malayi sodium-independent organic anion transporter family protein 0.0047 0.0067 0.0067
Brugia malayi hypothetical protein 0.0164 0.0388 0.0388
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0093 0.0192 0.0192
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Entamoeba histolytica cysteine proteinase, putative 0.0087 0.0176 0.4602
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0107 0.0232 0.0232
Brugia malayi hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Plasmodium falciparum serine repeat antigen 1 0.0042 0.0053 0.0921
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0388 0.0388
Giardia lamblia Kinase, CMGC MAPK 0.0114 0.025 0.4126
Loa Loa (eye worm) neuropeptide F receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Plasmodium vivax serine-repeat antigen (SERA) 0.0042 0.0053 0.0921
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Echinococcus granulosus orexin receptor type 2 0.0164 0.0388 0.0388
Onchocerca volvulus 0.0093 0.0192 0.4627
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0042 0.0053 0.0053
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0164 0.0388 0.0388
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Onchocerca volvulus 0.0164 0.0388 1
Plasmodium falciparum serine repeat antigen 5 0.0042 0.0053 0.0921
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0114 0.025 0.4482
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0093 0.0192 0.0192
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0093 0.0192 0.1076
Brugia malayi hypothetical protein 0.0164 0.0388 0.0388
Schistosoma mansoni RAR-like nuclear receptor 0.0044 0.0057 0.0057
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0107 0.0232 0.0232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0356 0.6573
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Brugia malayi putative neuropeptide receptor NPR1 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0185 0.0445 0.0445
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0044 0.0057 0.0057
Entamoeba histolytica cysteine proteinase 2 0.0087 0.0176 0.4602
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0107 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0042 0.0053 0.0053
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0042 0.0053 0.0921
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Brugia malayi NADH-dependent xylose reductase 0.0031 0.0022 0.0022
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0107 0.0232 0.0232
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0152 0.0356 0.6573
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0107 0.0232 0.0232
Onchocerca volvulus 0.0093 0.0192 0.4627
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Plasmodium falciparum serine repeat antigen 9 0.0042 0.0053 0.0921
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0042 0.0053 0.0605
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Schistosoma mansoni coup transcription factor 0.0044 0.0057 0.0057
Onchocerca volvulus 0.0044 0.0057 0.0945
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0152 0.0356 0.0356
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Brugia malayi hypothetical protein 0.0093 0.0192 0.0192
Onchocerca volvulus 0.0164 0.0388 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0388 0.0388
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0107 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) oxidoreductase 0.0107 0.0232 0.0232
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0152 0.0356 0.0356
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0044 0.0057 0.0057
Echinococcus multilocularis expressed protein 0.0361 0.0929 0.0929
Trichomonas vaginalis aldo-keto reductase, putative 0.0107 0.0232 0.4131
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0164 0.0388 0.0388
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0388 0.0388
Schistosoma mansoni single-minded 0.0055 0.0088 0.0088
Onchocerca volvulus 0.0164 0.0388 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0093 0.0192 0.0192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0356 0.6573
Onchocerca volvulus 0.0164 0.0388 1
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0093 0.0192 0.0192
Plasmodium falciparum serine repeat antigen 3 0.0042 0.0053 0.0921
Schistosoma mansoni hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Echinococcus multilocularis FTZ F1 alpha 0.0044 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Onchocerca volvulus 0.0164 0.0388 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0107 0.0232 0.0232
Trypanosoma cruzi aldo-keto reductase 0.0107 0.0232 0.1333
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0053 0.0605
Onchocerca volvulus 0.0107 0.0232 0.5732
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0042 0.0053 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0042 0.0053 0.0605
Brugia malayi sodium-independent organic anion transporter family protein 0.0047 0.0067 0.0067
Brugia malayi hypothetical protein 0.0047 0.0067 0.0067
Brugia malayi MAP kinase sur-1 0.0114 0.025 0.025
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Schistosoma mansoni cathepsin S (C01 family) 0.0042 0.0053 0.0053
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0093 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0152 0.0356 0.6573
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.0057
Onchocerca volvulus 0.0093 0.0192 0.4627
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0026 0.0026
Entamoeba histolytica cysteine protease, putative 0.0042 0.0053 0.0921
Schistosoma mansoni hypothetical protein 0.0164 0.0388 0.0388
Echinococcus granulosus serotonin receptor 0.0164 0.0388 0.0388
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0114 0.025 0.1447
Brugia malayi Cathepsin L-like precursor 0.0152 0.0356 0.0356
Schistosoma mansoni cathepsin F (C01 family) 0.0152 0.0356 0.0356
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0107 0.0232 0.0232
Echinococcus granulosus expressed protein 0.0361 0.0929 0.0929
Brugia malayi photoreceptor-specific nuclear receptor 0.0044 0.0057 0.0057
Trichomonas vaginalis aldo-keto reductase, putative 0.0107 0.0232 0.4131
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0047 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0045 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Echinococcus multilocularis aldo keto reductase 0.0107 0.0232 0.0232
Brugia malayi hypothetical protein 0.0164 0.0388 0.0388
Entamoeba histolytica aldose reductase, putative 0.0107 0.0232 0.6286
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0164 0.0388 0.0388
Schistosoma mansoni growth hormone secretagogue receptor 0.0164 0.0388 0.0388
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.025 0.4482
Loa Loa (eye worm) hypothetical protein 0.0042 0.0053 0.0053
Brugia malayi Papain family cysteine protease containing protein 0.0152 0.0356 0.0356
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0093 0.0192 0.5074
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0093 0.0192 0.0192
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0152 0.0356 0.0356
Brugia malayi bHLH-PAS transcription factor 0.0041 0.0049 0.0049
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0675 0.1794 0.1794
Echinococcus multilocularis musashi 0.0033 0.0026 0.0026
Toxoplasma gondii cathepsin CPL 0.0152 0.0356 0.6573
Trypanosoma brucei protein tyrosine phosphatase 1 0.0093 0.0192 0.3335
Loa Loa (eye worm) hypothetical protein 0.0047 0.0067 0.0067
Echinococcus multilocularis mitogen activated protein kinase 0.0114 0.025 0.025
Brugia malayi Steroid receptor seven-up type 2 0.0044 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Echinococcus granulosus neuropeptides capa receptor 0.0164 0.0388 0.0388
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0093 0.0192 0.0192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0087 0.0176 0.3024
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Brugia malayi hypothetical protein 0.0093 0.0192 0.0192
Schistosoma mansoni neuropeptide F-like receptor 0.0164 0.0388 0.0388
Echinococcus multilocularis neuropeptide receptor A26 0.0164 0.0388 0.0388
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0107 0.0232 0.0232
Brugia malayi hypothetical protein 0.0164 0.0388 0.0388
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0044 0.0057 0.0057
Brugia malayi AKH receptor 0.0164 0.0388 0.0388
Brugia malayi hypothetical protein 0.0164 0.0388 0.0388
Echinococcus granulosus tm gpcr rhodopsin 0.0164 0.0388 0.0388
Echinococcus multilocularis lamin 0.0033 0.0026 0.0026
Entamoeba histolytica hypothetical protein 0.0043 0.0056 0.1018
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Entamoeba histolytica cysteine protease, putative 0.0042 0.0053 0.0921
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Echinococcus granulosus cysteine protease 0.0087 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Onchocerca volvulus 0.0033 0.0026 0.011
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Giardia lamblia Aldose reductase 0.0107 0.0232 0.3753
Echinococcus multilocularis thyroid hormone receptor alpha 0.0044 0.0057 0.0057
Echinococcus granulosus allatostatin A receptor 0.0164 0.0388 0.0388
Echinococcus multilocularis fmrfamide receptor 0.0164 0.0388 0.0388
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0007 0.0007
Loa Loa (eye worm) oxidoreductase 0.0107 0.0232 0.0232
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0093 0.0192 0.0192
Brugia malayi hypothetical protein 0.0093 0.0192 0.0192
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0093 0.0192 0.0192
Trypanosoma cruzi major cysteine proteinase, putative 0.0042 0.0053 0.0195
Plasmodium vivax vivapain-3 0.0087 0.0176 0.4602
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0093 0.0192 0.5074
Schistosoma mansoni hypothetical protein 0.0164 0.0388 0.0388
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0164 0.0388 0.0388
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0164 0.0388 0.0388
Schistosoma mansoni neuropeptide f receptor 76f 0.0164 0.0388 0.0388
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0093 0.0192 0.0192
Onchocerca volvulus 0.0152 0.0356 0.912
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0047 0.0067 0.0067
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Echinococcus granulosus g protein coupled receptor 0.0164 0.0388 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0042 0.0053 0.0605
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0107 0.0232 0.0232
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0044 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Brugia malayi cathepsin L-like cysteine proteinase 0.0042 0.0053 0.0053
Schistosoma mansoni neuropeptide receptor 0.0164 0.0388 0.0388
Brugia malayi hypothetical protein 0.0164 0.0388 0.0388
Giardia lamblia Cathepsin B precursor 0.0216 0.053 1
Echinococcus multilocularis g-protein coupled receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0152 0.0356 0.0356
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0164 0.0388 1
Toxoplasma gondii cathepsin B 0.0216 0.053 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.3655 1 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Echinococcus multilocularis neuropeptides capa receptor 0.0164 0.0388 0.0388
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0074 0.1015
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0044 0.0057 0.0057
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Echinococcus granulosus neuropeptide FF receptor 2 0.0164 0.0388 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0233 0.4153
Entamoeba histolytica cysteine protease, putative 0.0042 0.0053 0.0921
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0031 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.0057
Trichomonas vaginalis aldo-keto reductase, putative 0.0107 0.0232 0.4131
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0107 0.0232 0.0232
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0093 0.0192 0.0192
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0107 0.0232 0.4131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0152 0.0356 0.6573
Onchocerca volvulus 0.0152 0.0356 0.912
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) TYRA-2 protein 0.0164 0.0388 0.0388
Trypanosoma brucei protein kinase, putative 0.0114 0.025 0.4482
Brugia malayi hypothetical protein 0.0043 0.0056 0.0056
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0152 0.0356 0.6573
Entamoeba histolytica cysteine protease, putative 0.0042 0.0053 0.0921
Trichomonas vaginalis aldo-keto reductase, putative 0.0107 0.0232 0.4131
Plasmodium vivax vivapain-1 0.0087 0.0176 0.4602
Onchocerca volvulus 0.0164 0.0388 1
Schistosoma mansoni neuropeptide F-like receptor 0.0164 0.0388 0.0388
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0152 0.0356 1
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0107 0.0232 0.4131
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0114 0.025 0.4482
Trichomonas vaginalis aldo-keto reductase, putative 0.0107 0.0232 0.4131
Leishmania major aldo-keto reductase-like protein 0.0107 0.0232 0.4131
Brugia malayi cathepsin F-like cysteine proteinase 0.0045 0.0059 0.0059
Echinococcus granulosus aldehyde reductase 0.0076 0.0146 0.0146
Echinococcus granulosus g-protein coupled receptor 0.0164 0.0388 0.0388
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0107 0.0232 0.0232
Trypanosoma cruzi MFS transporter, putative 0.0047 0.0067 0.0284
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0107 0.0232 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0164 0.0388 0.0388
Schistosoma mansoni cathepsin F (C01 family) 0.0108 0.0233 0.0233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Onchocerca volvulus Protein ultraspiracle homolog 0.0044 0.0057 0.0945
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0603 0.1597 0.1597
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0042 0.0053 0.0053
Entamoeba histolytica hypothetical protein 0.0042 0.0053 0.0921
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0093 0.0192 0.0192
Trypanosoma cruzi cysteine proteinase, putative 0.0087 0.0176 0.0976
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0044 0.0057 0.0057
Echinococcus granulosus g protein coupled receptor 0.0164 0.0388 0.0388
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0164 0.0388 0.0388
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0093 0.0192 0.0192
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0042 0.0053 0.0921
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0042 0.0053 0.0921
Onchocerca volvulus 0.0107 0.0232 0.5732
Onchocerca volvulus 0.0093 0.0192 0.4627
Brugia malayi Papain family cysteine protease containing protein 0.0087 0.0176 0.0176
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0603 0.1597 0.1597
Echinococcus granulosus neuropeptides capa receptor 0.0164 0.0388 0.0388
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0356 0.6573
Echinococcus multilocularis cysteine protease 0.0152 0.0356 0.0356
Loa Loa (eye worm) oxidoreductase 0.0107 0.0232 0.0232
Brugia malayi nuclear hormone receptor 0.0044 0.0057 0.0057
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0056 0.0056
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0114 0.025 0.1447
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Onchocerca volvulus 0.0107 0.0232 0.5732
Loa Loa (eye worm) oxidoreductase 0.0107 0.0232 0.0232
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0087 0.0176 0.0176
Brugia malayi Cathepsin L-like precursor 0.0152 0.0356 0.0356
Loa Loa (eye worm) fibroinase 0.0152 0.0356 0.0356
Leishmania major cathepsin L-like protease 0.0152 0.0356 0.6573
Onchocerca volvulus 0.0164 0.0388 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0053 0.0053
Brugia malayi Cathepsin L-like precursor 0.0045 0.0059 0.0059
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0093 0.0192 0.0192
Onchocerca volvulus Cathepsin L homolog 0.0152 0.0356 0.912
Schistosoma mansoni cathepsin F (C01 family) 0.0152 0.0356 0.0356
Brugia malayi Protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Brugia malayi G protein-coupled receptor F59B2.13 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0152 0.0356 0.0356
Brugia malayi PAS domain containing protein 0.0055 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0087 0.0176 0.0176
Leishmania major cysteine peptidase A (CPA) 0.0152 0.0356 0.6573
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0044 0.0057 0.0945
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0057 0.0057
Schistosoma mansoni hypothetical protein 0.0205 0.05 0.05
Brugia malayi Cathepsin L-like precursor 0.0152 0.0356 0.0356
Onchocerca volvulus 0.0093 0.0192 0.4627
Echinococcus granulosus single minded 2 0.0041 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0026
Schistosoma mansoni amine GPCR 0.0564 0.149 0.149
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0093 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0042 0.0053 0.0605
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0164 0.0388 0.0388
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0044 0.0057 0.0057
Onchocerca volvulus 0.0093 0.0192 0.4627
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0044 0.0057 0.0057
Trichomonas vaginalis aldo-keto reductase, putative 0.0107 0.0232 0.4131
Brugia malayi hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0042 0.0053 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0093 0.0192 0.0192
Onchocerca volvulus 0.0164 0.0388 1
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0057 0.0057
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0093 0.0192 0.0192
Toxoplasma gondii transporter, major facilitator family protein 0.0047 0.0067 0.088
Brugia malayi hypothetical protein 0.0047 0.0067 0.0067
Brugia malayi Papain family cysteine protease containing protein 0.0042 0.0053 0.0053
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0231 0.0573 0.0573
Brugia malayi Dopamine receptor protein 1 0.0164 0.0388 0.0388
Brugia malayi G-protein coupled receptor 0.0164 0.0388 0.0388
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0044 0.0057 0.0057
Entamoeba histolytica cysteine proteinase, putative 0.0087 0.0176 0.4602
Entamoeba histolytica aldose reductase, putative 0.0107 0.0232 0.6286
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0164 0.0388 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0053 0.0605
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0057 0.0057
Echinococcus granulosus aldo keto reductase 0.0107 0.0232 0.0232
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0388 0.0388
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0164 0.0388 0.0388
Schistosoma mansoni thyroid hormone receptor 0.0044 0.0057 0.0057
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0042 0.0053 0.0053
Echinococcus granulosus cathepsin L cysteine protease 0.0087 0.0176 0.0176
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0107 0.0232 0.0232
Echinococcus granulosus Solute carrier organic anion transporter family 0.0047 0.0067 0.0067
Echinococcus multilocularis fmrfamide receptor 0.0164 0.0388 0.0388
Brugia malayi G-protein coupled receptor 0.0164 0.0388 0.0388
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0087 0.0176 0.0976
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Echinococcus multilocularis cathepsin L 0.0042 0.0053 0.0053
Onchocerca volvulus 0.0041 0.0049 0.0726
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0042 0.0053 0.0921
Echinococcus granulosus rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Entamoeba histolytica cysteine protease, putative 0.0042 0.0053 0.0921
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Echinococcus multilocularis cysteine protease 0.0152 0.0356 0.0356
Echinococcus granulosus biogenic amine 5HT receptor 0.0164 0.0388 0.0388
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0093 0.0192 0.0192
Echinococcus granulosus aldo keto reductase 0.0107 0.0232 0.0232
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0057 0.0057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0044 0.0057 0.0057
Onchocerca volvulus 0.0093 0.0192 0.4627
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0042 0.0053 0.0921
Schistosoma mansoni alpha-1 adrenergic receptor 0.0164 0.0388 0.0388
Brugia malayi hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0045 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Brugia malayi cathepsin Z-like cysteine proteinase 0.0042 0.0053 0.0053
Onchocerca volvulus 0.0093 0.0192 0.4627
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0042 0.0053 0.0921
Echinococcus granulosus 7tm_1 domain containing protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypoxia-induced factor 1 0.017 0.0406 0.0406
Trichomonas vaginalis aldo-keto reductase, putative 0.0107 0.0232 0.4131
Leishmania major cathepsin L-like protease 0.0152 0.0356 0.6573
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.025 0.4482
Entamoeba histolytica cysteine protease, putative 0.0042 0.0053 0.0921
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0093 0.0192 0.0192
Entamoeba histolytica hypothetical protein 0.0043 0.0056 0.1018
Onchocerca volvulus 0.0107 0.0232 0.5732
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0164 0.0388 0.0388
Onchocerca volvulus 0.0164 0.0388 1
Echinococcus multilocularis orexin receptor type 2 0.0164 0.0388 0.0388
Brugia malayi steroid hormone receptor 0.0044 0.0057 0.0057
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0107 0.0232 0.4131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Brugia malayi hypothetical protein 0.0164 0.0388 0.0388
Toxoplasma gondii cathepsin CPC1 0.0042 0.0053 0.0605
Loa Loa (eye worm) ctsf protein 0.0152 0.0356 0.0356
Echinococcus granulosus mitogen activated protein kinase 0.0114 0.025 0.025
Entamoeba histolytica cysteine proteinase, putative 0.0087 0.0176 0.4602
Echinococcus multilocularis dro:myosuppressin receptor 0.0164 0.0388 0.0388
Trichomonas vaginalis aldo-keto reductase, putative 0.0107 0.0232 0.4131
Echinococcus granulosus cathepsin l cysteine peptidase 0.0152 0.0356 0.0356
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0093 0.0192 0.0192
Brugia malayi ORL1-like opioid receptor 0.0164 0.0388 0.0388
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0056 0.0056
Echinococcus multilocularis neuropeptide Y receptor 0.0164 0.0388 0.0388
Giardia lamblia Cathepsin B precursor 0.0216 0.053 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0164 0.0388 0.0388
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.025 0.4482
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Onchocerca volvulus Putative organic anion transporter 0.0047 0.0067 0.1222
Trypanosoma cruzi aldo/keto reductase, putative 0.0107 0.0232 0.1333
Schistosoma mansoni lamin 0.0033 0.0026 0.0026
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0164 0.0388 0.0388
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0093 0.0192 0.0192
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Brugia malayi neuropeptide F receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0032 0.0025 0.0025
Loa Loa (eye worm) G-protein coupled receptor 0.0164 0.0388 0.0388
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0093 0.0192 0.0192
Loa Loa (eye worm) cathepsin B 0.0216 0.053 0.053
Schistosoma mansoni amine GPCR 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0388 0.0388
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0042 0.0053 0.0921
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.0233 0.4153
Brugia malayi Dopamine receptor protein 2 0.0164 0.0388 0.0388
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0107 0.0232 0.4131
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0114 0.025 0.025
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0107 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Brugia malayi cathepsin L-like precursor 0.0108 0.0233 0.0233
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0164 0.0388 0.0388
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0042 0.0053 0.0921
Trichomonas vaginalis aldo-keto reductase, putative 0.0107 0.0232 0.4131
Mycobacterium tuberculosis Probable oxidoreductase 0.0107 0.0232 1
Onchocerca volvulus 0.0047 0.0067 0.1222
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Echinococcus multilocularis g protein coupled receptor 0.0164 0.0388 0.0388
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0044 0.0057 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0044 0.0057 0.0057
Onchocerca volvulus 0.0047 0.0067 0.1222
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0107 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0093 0.0192 0.0192
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Brugia malayi cathepsin L precursor 0.0042 0.0053 0.0053
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0057 0.0057
Onchocerca volvulus 0.0152 0.0356 0.912
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0042 0.0053 0.0053
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0042 0.0053 0.0053
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0164 0.0388 0.0388
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0108 0.0233 0.1341
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0042 0.0053 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0042 0.0053 0.0053
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0093 0.0192 0.0192
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0042 0.0053 0.0053
Trypanosoma cruzi cysteine peptidase, putative 0.0152 0.0356 0.2121
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Entamoeba histolytica cysteine protease, putative 0.0087 0.0176 0.4602
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Schistosoma mansoni biogenic amine receptor 0.0164 0.0388 0.0388
Trichomonas vaginalis serine threonine-protein kinase, putative 0.005 0.0074 0.1015
Plasmodium vivax unspecified product 0.0087 0.0176 0.4602
Trichomonas vaginalis aldo/keto reductase, putative 0.0107 0.0232 0.4131
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0042 0.0053 0.0605
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0216 0.053 0.3228
Brugia malayi Cathepsin L-like precursor 0.0108 0.0233 0.0233
Brugia malayi larval opioid receptor 0.0164 0.0388 0.0388
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0114 0.025 0.4482
Loa Loa (eye worm) hypothetical protein 0.0164 0.0388 0.0388
Schistosoma mansoni biogenic amine (5HT) receptor 0.0164 0.0388 0.0388
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0356 0.6573
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Echinococcus granulosus cathepsin l1 0.0152 0.0356 0.0356
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0093 0.0192 0.0192
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0093 0.0192 0.0192
Schistosoma mansoni amine GPCR 0.0164 0.0388 0.0388
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0152 0.0356 0.6573
Echinococcus multilocularis aldehyde reductase 0.0076 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0108 0.0233 0.0233
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0164 0.0388 0.0388
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0044 0.0057 0.0057
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0093 0.0192 0.0192
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.025 0.025
Schistosoma mansoni potassium channel beta 0.0031 0.0022 0.0022
Echinococcus granulosus FTZ F1 alpha 0.0044 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0053 0.0605
Echinococcus multilocularis rhodopsin orphan GPCR 0.0164 0.0388 0.0388
Loa Loa (eye worm) neuropeptide F receptor 0.0164 0.0388 0.0388
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0042 0.0053 0.0921
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0216 0.053 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0044 0.0057 0.0057
Brugia malayi nuclear receptor NHR-88 0.0044 0.0057 0.0057
Echinococcus granulosus neuropeptide s receptor 0.0164 0.0388 0.0388
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0107 0.0232 0.0232
Brugia malayi sulfakinin receptor protein 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0192
Onchocerca volvulus 0.0093 0.0192 0.4627
Echinococcus multilocularis serotonin receptor 0.0164 0.0388 0.0388
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0093 0.0192 0.0192
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0093 0.0192 0.0192
Echinococcus multilocularis cathepsin L cysteine protease 0.0152 0.0356 0.0356
Entamoeba histolytica cysteine proteinase, putative 0.0087 0.0176 0.4602
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0152 0.0356 0.6573
Trypanosoma cruzi cysteine peptidase, putative 0.0152 0.0356 0.2121
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0093 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0152 0.0356 0.6573
Schistosoma mansoni cathepsin s 0.0045 0.0059 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0044 0.0057 0.0057
Echinococcus multilocularis neuropeptides capa receptor 0.0164 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0108 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0042 0.0053 0.0053
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0093 0.0192 0.0192
Trypanosoma cruzi cysteine peptidase, putative 0.0087 0.0176 0.0976
Plasmodium falciparum serine repeat antigen 4 0.0042 0.0053 0.0921

Activities

Activity type Activity value Assay description Source Reference
MEC (functional) = 0.5 ug ml-1 Minimum effective concentration required to induce interferon (IFN) production in human peripheral blood mononuclear cells (hPBMC) ChEMBL. 15887957

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.