Detailed information for compound 373531

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 404.501 | Formula: C25H28N2O3
  • H donors: 1 H acceptors: 1 LogP: 4.48 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(OC)cc(c1)C(=O)NC1CCN(CC1)Cc1ccc2c(c1)cccc2
  • InChi: 1S/C25H28N2O3/c1-29-23-14-21(15-24(16-23)30-2)25(28)26-22-9-11-27(12-10-22)17-18-7-8-19-5-3-4-6-20(19)13-18/h3-8,13-16,22H,9-12,17H2,1-2H3,(H,26,28)
  • InChiKey: GOQYJGUAYWTBMB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens melanin-concentrating hormone receptor 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax hypothetical protein, conserved 0.0158 0.0214 0.0673
Entamoeba histolytica cyclin family protein 0.0255 0.0392 0.1138
Brugia malayi hypothetical protein 0.008 0.0071 0.0066
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Trichomonas vaginalis cyclin D, putative 0.0061 0.0036 0.0054
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0542 0.0923 0.2871
Trypanosoma brucei heat shock protein, putative 0.0065 0.0043 0.0028
Plasmodium falciparum transporter, putative 0.016 0.0218 0.0687
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0052 0.0019 0.5
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Loa Loa (eye worm) cyclin C 0.0061 0.0036 0.0031
Echinococcus multilocularis carboxylesterase 5A 0.5465 1 1
Brugia malayi heat shock protein 90 0.0065 0.0043 0.0039
Giardia lamblia Kinase, PLK 0.0121 0.0145 0.0402
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0294 0.0465 0.046
Onchocerca volvulus 0.0294 0.0465 0.1467
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0553 0.0943 0.0939
Onchocerca volvulus Cyclin L homolog 0.0061 0.0036 0.0114
Mycobacterium tuberculosis Conserved hypothetical protein 0.0158 0.0214 0.052
Echinococcus multilocularis g protein coupled receptor 0.0294 0.0465 0.046
Trypanosoma cruzi casein kinase, putative 0.0065 0.0042 0.0157
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0294 0.0465 0.046
Echinococcus granulosus orexin receptor type 2 0.0294 0.0465 0.046
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0294 0.0465 0.046
Brugia malayi G protein-coupled receptor 0.0294 0.0465 0.046
Schistosoma mansoni sodium/chloride dependent transporter 0.016 0.0218 0.0213
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0042 0.0037
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0533 0.0906 0.0902
Trichomonas vaginalis cyclins, putative 0.0433 0.0721 0.2229
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Onchocerca volvulus 0.0294 0.0465 0.1467
Schistosoma mansoni nephrin 0.008 0.0071 0.0066
Brugia malayi larval opioid receptor 0.0294 0.0465 0.046
Schistosoma mansoni neuropeptide receptor 0.0294 0.0465 0.046
Trichomonas vaginalis CMGC family protein kinase 0.1495 0.2679 0.8451
Echinococcus multilocularis Cyclin L1 0.0061 0.0036 0.0031
Echinococcus multilocularis neuropeptide FF receptor 2 0.0294 0.0465 0.046
Brugia malayi hypothetical protein 0.0061 0.0036 0.0031
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.0134 0.013
Echinococcus multilocularis casein kinase I delta 0.0065 0.0042 0.0037
Loa Loa (eye worm) hypothetical protein 0.0158 0.0214 0.0209
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0294 0.0465 0.046
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0294 0.0465 0.046
Echinococcus multilocularis heat shock protein 90 0.0065 0.0043 0.0039
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.1759 0.3166 1
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0121 0.0145 0.0141
Echinococcus multilocularis cyclin A3 4 0.0061 0.0036 0.0031
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.016 0.0218 0.0213
Onchocerca volvulus 0.0158 0.0214 0.0676
Onchocerca volvulus 0.0923 0.1625 0.5133
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0294 0.0465 0.046
Entamoeba histolytica hypothetical protein 0.0095 0.0098 0.0198
Trichomonas vaginalis cyclin D, putative 0.0255 0.0392 0.1186
Schistosoma mansoni adenoreceptor 0.0294 0.0465 0.046
Trichomonas vaginalis cyclin B3, putative 0.0061 0.0036 0.0054
Trypanosoma cruzi cdc2-related kinase 3 0.0553 0.0943 0.352
Echinococcus multilocularis G1:S specific cyclin D1 0.0061 0.0036 0.0031
Trypanosoma cruzi polo-like protein kinase, putative 0.0121 0.0145 0.0543
Trypanosoma brucei heat shock protein, putative 0.0065 0.0043 0.0028
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Brugia malayi Cyclin, N-terminal domain containing protein 0.0061 0.0036 0.0031
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.1759 0.3166 1
Schistosoma mansoni heat shock protein 0.0065 0.0043 0.0039
Plasmodium falciparum glutathione reductase 0.0062 0.0037 0.0002
Echinococcus multilocularis cyclins 0.0255 0.0392 0.0388
Loa Loa (eye worm) serotonin transporter b 0.0942 0.166 0.1656
Trichomonas vaginalis cyclin A, putative 0.0061 0.0036 0.0054
Entamoeba histolytica cell division protein kinase 2, putative 0.0553 0.0943 0.2897
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0158 0.0214 0.0673
Schistosoma mansoni vesicular amine transporter 0.008 0.0071 0.0066
Trypanosoma cruzi casein kinase, putative 0.0065 0.0042 0.0157
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0923 0.1625 0.1622
Echinococcus multilocularis cyclin 0.0061 0.0036 0.0031
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0062 0.0037 0.0047
Schistosoma mansoni sodium/chloride dependent transporter 0.0183 0.026 0.0255
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0533 0.0906 0.0902
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0294 0.0465 0.046
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0294 0.0465 0.046
Echinococcus granulosus roundabout 2 0.008 0.0071 0.0066
Loa Loa (eye worm) solute carrier family 6 member 4 0.0942 0.166 0.1656
Echinococcus granulosus dual specificity 0.0081 0.0073 0.0068
Echinococcus granulosus g protein coupled receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Onchocerca volvulus Serine\/threonine kinase homolog 0.0121 0.0145 0.0459
Trypanosoma cruzi cdc2-related kinase 1 0.0553 0.0943 0.352
Brugia malayi Cyclin, N-terminal domain containing protein 0.0061 0.0036 0.0031
Schistosoma mansoni cyclin G2 0.0061 0.0036 0.0031
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0294 0.0465 0.046
Onchocerca volvulus 0.1495 0.2679 0.846
Echinococcus multilocularis cyclins 0.0255 0.0392 0.0388
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.016 0.0218 0.0687
Brugia malayi cell division control protein 2 homolog 0.0553 0.0943 0.0939
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0294 0.0465 0.046
Trypanosoma cruzi hypothetical protein, conserved 0.0542 0.0923 0.3444
Trichomonas vaginalis cyclin B, putative 0.0061 0.0036 0.0054
Echinococcus granulosus G2:mitotic specific cyclin B3 0.1053 0.1864 0.186
Echinococcus granulosus neuroglian 0.008 0.0071 0.0066
Trypanosoma cruzi heat shock protein 90, putative 0.0052 0.0019 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0255 0.0392 0.1186
Schistosoma mansoni biogenic amine receptor 0.0294 0.0465 0.046
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0294 0.0465 0.046
Mycobacterium ulcerans carboxylesterase, LipT 0.0923 0.1625 0.3977
Echinococcus granulosus cyclin B3 1 0.0255 0.0392 0.0388
Echinococcus multilocularis neuropeptides capa receptor 0.0294 0.0465 0.046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0294 0.0465 0.046
Echinococcus granulosus somatostatin receptor 0.0294 0.0465 0.046
Schistosoma mansoni cyclin d 0.0061 0.0036 0.0031
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0294 0.0465 0.046
Echinococcus granulosus heat shock protein 90 0.0052 0.0019 0.0014
Echinococcus granulosus neuropeptides capa receptor 0.0294 0.0465 0.046
Schistosoma mansoni amine oxidase 0.0158 0.0214 0.0209
Loa Loa (eye worm) hypothetical protein 0.0255 0.0394 0.0389
Brugia malayi G protein-coupled receptor F59B2.13 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.1303 0.2325 0.2322
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0923 0.1625 0.1622
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Echinococcus multilocularis Immunoglobulin 0.008 0.0071 0.0066
Loa Loa (eye worm) glutathione reductase 0.0062 0.0037 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.0294 0.0465 0.046
Echinococcus granulosus cyclins 0.0255 0.0392 0.0388
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.1217 0.2167 0.5729
Echinococcus granulosus protein kinase shaggy 0.1495 0.2679 0.2675
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0553 0.0943 0.3474
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Trichomonas vaginalis cyclins, putative 0.0061 0.0036 0.0054
Giardia lamblia Kinase, CMGC CDK 0.0553 0.0943 0.2936
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1495 0.2679 1
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0158 0.0214 0.0673
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0923 0.1625 0.4286
Trichomonas vaginalis CMGC family protein kinase 0.0553 0.0943 0.2936
Echinococcus granulosus peptide allatostatin:somatostatin 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Loa Loa (eye worm) neuropeptide F receptor 0.0294 0.0465 0.046
Brugia malayi Dopamine receptor protein 1 0.0294 0.0465 0.046
Trypanosoma brucei heat shock protein, putative 0.0065 0.0043 0.0028
Onchocerca volvulus 0.0294 0.0465 0.1467
Schistosoma mansoni opsin-like receptor 0.0294 0.0465 0.046
Echinococcus granulosus rhodopsin orphan GPCR 0.0294 0.0465 0.046
Brugia malayi follicle stimulating hormone receptor 0.0507 0.0857 0.0852
Loa Loa (eye worm) hypothetical protein 0.035 0.0567 0.0563
Trichomonas vaginalis cyclins, putative 0.0255 0.0392 0.1186
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Echinococcus multilocularis neuropeptide receptor A26 0.0294 0.0465 0.046
Echinococcus granulosus neuropeptide receptor 0.0294 0.0465 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0145 0.0402
Brugia malayi GnHR receptor homolog 0.0294 0.0465 0.046
Echinococcus granulosus cyclins 0.0255 0.0392 0.0388
Schistosoma mansoni neuropeptide receptor 0.0294 0.0465 0.046
Brugia malayi Sodium:neurotransmitter symporter family protein 0.016 0.0218 0.0213
Trypanosoma brucei heat shock protein, putative 0.0065 0.0043 0.0028
Loa Loa (eye worm) hypothetical protein 0.0061 0.0036 0.0031
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0061 0.0036 0.0031
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0158 0.0214 0.0209
Leishmania major casein kinase, putative 0.0065 0.0042 0.0087
Echinococcus granulosus cyclin 0.0061 0.0036 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0294 0.0465 0.046
Onchocerca volvulus 0.0294 0.0465 0.1467
Schistosoma mansoni neuropeptide receptor 0.0294 0.0465 0.046
Brugia malayi AKH receptor 0.0294 0.0465 0.046
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0294 0.0465 0.046
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0294 0.0465 0.046
Brugia malayi amine oxidase, flavin-containing family protein 0.0158 0.0214 0.0209
Echinococcus multilocularis roundabout 2 0.008 0.0071 0.0066
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1495 0.2679 0.2675
Brugia malayi hypothetical protein 0.0294 0.0465 0.046
Brugia malayi hypothetical protein 0.0255 0.0394 0.0389
Trypanosoma cruzi casein kinase, putative 0.0065 0.0042 0.0157
Trypanosoma brucei mitotic cyclin 6 0.0433 0.0721 0.259
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0065 0.0042 0.0157
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0433 0.0721 0.2638
Trypanosoma brucei heat shock protein, putative 0.0065 0.0043 0.0028
Schistosoma mansoni hypothetical protein 0.0294 0.0465 0.046
Brugia malayi SWIRM domain containing protein 0.0158 0.0214 0.0209
Onchocerca volvulus 0.0294 0.0465 0.1467
Trypanosoma cruzi UDP-galactopyranose mutase 0.0158 0.0214 0.0799
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Giardia lamblia Kinase, CMGC CDK 0.0553 0.0943 0.2936
Loa Loa (eye worm) neuropeptide F receptor 0.0294 0.0465 0.046
Trichomonas vaginalis cyclin B, putative 0.0433 0.0721 0.2229
Onchocerca volvulus 0.0294 0.0465 0.1467
Schistosoma mansoni amine oxidase 0.0158 0.0214 0.0209
Loa Loa (eye worm) carboxylesterase 0.0923 0.1625 0.1622
Echinococcus granulosus hypothetical protein 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0061 0.0036 0.0031
Echinococcus multilocularis cyclin G2 0.0061 0.0036 0.0031
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Echinococcus granulosus defective proboscis extension response 0.008 0.0071 0.0066
Plasmodium falciparum protein kinase 5 0.0553 0.0943 0.3432
Brugia malayi hypothetical protein 0.0294 0.0465 0.046
Onchocerca volvulus 0.0294 0.0465 0.1467
Trypanosoma brucei heat shock protein, putative 0.0065 0.0043 0.0028
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0294 0.0465 0.046
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0073 0.0172
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0542 0.0923 0.3355
Toxoplasma gondii histone lysine-specific demethylase 0.0158 0.0214 0.0673
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0294 0.0465 0.046
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0294 0.0465 0.046
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0121 0.0145 0.0141
Echinococcus granulosus cyclin B 0.0433 0.0721 0.0716
Leishmania major mitotic cyclin, putative 0.0061 0.0036 0.0064
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0061 0.0036 0.0031
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Brugia malayi Amyloid A4 extracellular domain containing protein 0.1653 0.2971 0.2968
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0294 0.0465 0.046
Giardia lamblia Hypothetical protein 0.0061 0.0036 0.0054
Loa Loa (eye worm) cyclin domain-containing protein 0.0061 0.0036 0.0031
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0073 0.0172
Entamoeba histolytica casein kinase 1, putative 0.0065 0.0042 0.0019
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0294 0.0465 0.046
Schistosoma mansoni biogenic amine (5HT) receptor 0.0294 0.0465 0.046
Brugia malayi neuropeptide F receptor 0.0294 0.0465 0.046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0294 0.0465 0.046
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Loa Loa (eye worm) hypothetical protein 0.008 0.0071 0.0066
Trichomonas vaginalis CK1 family protein kinase 0.0065 0.0042 0.0073
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0294 0.0465 0.046
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0081 0.0073 0.0068
Loa Loa (eye worm) hypothetical protein 0.0923 0.1625 0.1622
Plasmodium falciparum casein kinase 1 0.0065 0.0042 0.0023
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0923 0.1625 0.4286
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.016 0.0218 0.0213
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Trypanosoma brucei cdc2-related kinase 1 0.0553 0.0943 0.3432
Echinococcus granulosus rhodopsin orphan GPCR 0.0294 0.0465 0.046
Brugia malayi Endoplasmin precursor 0.0065 0.0043 0.0039
Schistosoma mansoni Neurotrimin precursor (hNT) 0.008 0.0071 0.0066
Entamoeba histolytica protein kinase domain containing protein 0.0211 0.0312 0.0881
Schistosoma mansoni serine/threonine protein kinase 0.0553 0.0943 0.0939
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0294 0.0465 0.046
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0121 0.0145 0.0141
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0294 0.0465 0.046
Giardia lamblia Kinase, CMGC GSK 0.1495 0.2679 0.8451
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0531 0.0901 0.0897
Trypanosoma brucei polo-like protein kinase 0.0121 0.0145 0.0414
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Trypanosoma cruzi cdc2-related kinase 3 0.0553 0.0943 0.352
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0294 0.0465 0.046
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.016 0.0218 0.0213
Echinococcus granulosus cyclin dependent kinase 0.0553 0.0943 0.0939
Giardia lamblia Heat shock protein HSP 90-alpha 0.0065 0.0043 0.0078
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0073 0.0172
Schistosoma mansoni biogenic amine receptor 0.0294 0.0465 0.046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0294 0.0465 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0145 0.0402
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0158 0.0214 1
Schistosoma mansoni Cyclin fold protein 0.0061 0.0036 0.0031
Giardia lamblia Kinase, CMGC GSK 0.1495 0.2679 0.8451
Trypanosoma brucei heat shock protein 90, putative 0.0065 0.0043 0.0028
Onchocerca volvulus 0.0294 0.0465 0.1467
Echinococcus multilocularis Immunoglobulin 0.008 0.0071 0.0066
Plasmodium falciparum amino acid transporter, putative 0.016 0.0218 0.0687
Loa Loa (eye worm) carboxylesterase 0.0923 0.1625 0.1622
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0054 0.0111
Echinococcus granulosus fmrfamide receptor 0.0294 0.0465 0.046
Trypanosoma cruzi mitotic cyclin, putative 0.0061 0.0036 0.0134
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0294 0.0465 0.046
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0553 0.0943 0.3474
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.016 0.0218 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0121 0.0145 0.0543
Echinococcus granulosus sodium and chloride dependent glycine 0.016 0.0218 0.0213
Echinococcus multilocularis dual specificity 0.0211 0.0312 0.0307
Echinococcus multilocularis rhodopsin orphan GPCR 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.008 0.0071 0.0066
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0073 0.0068
Brugia malayi putative neuropeptide receptor 0.0294 0.0465 0.046
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0036 0.0054
Onchocerca volvulus 0.0061 0.0036 0.0114
Onchocerca volvulus 0.0923 0.1625 0.5133
Brugia malayi ORL1-like opioid receptor 0.0294 0.0465 0.046
Plasmodium falciparum cyclin 0.0255 0.0392 0.1348
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0942 0.166 0.1656
Entamoeba histolytica cell division protein kinase 2, putative 0.0553 0.0943 0.2897
Echinococcus granulosus g protein coupled receptor 0.0294 0.0465 0.046
Echinococcus granulosus twitchin 0.0103 0.0112 0.0108
Brugia malayi casein kinase 1, delta 0.0065 0.0042 0.0037
Echinococcus granulosus tm gpcr rhodopsin 0.0294 0.0465 0.046
Echinococcus granulosus alpha 1A adrenergic receptor 0.0294 0.0465 0.046
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0294 0.0465 0.1467
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0923 0.1625 0.5104
Entamoeba histolytica heat shock protein 90, putative 0.0065 0.0043 0.0024
Entamoeba histolytica protein tyrosine phosphatase, putative 0.1759 0.3166 1
Trichomonas vaginalis cyclins, putative 0.0433 0.0721 0.2229
Schistosoma mansoni hypothetical protein 0.0061 0.0036 0.0031
Echinococcus granulosus cyclins 0.0255 0.0392 0.0388
Echinococcus multilocularis rhodopsin orphan GPCR 0.0294 0.0465 0.046
Schistosoma mansoni amine GPCR 0.0294 0.0465 0.046
Brugia malayi Cyclin, N-terminal domain containing protein 0.0433 0.0721 0.0716
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.016 0.0218 0.0213
Echinococcus multilocularis sodium and chloride dependent glycine 0.016 0.0218 0.0213
Brugia malayi Cyclin, N-terminal domain containing protein 0.0061 0.0036 0.0031
Trichomonas vaginalis cyclins, putative 0.0433 0.0721 0.2229
Loa Loa (eye worm) endoplasmin 0.0065 0.0043 0.0039
Echinococcus granulosus casein kinase I delta 0.0065 0.0042 0.0037
Loa Loa (eye worm) heat shock protein 90 0.0065 0.0043 0.0039
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0294 0.0465 0.046
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0121 0.0145 0.0475
Echinococcus granulosus dual specificity 0.0211 0.0312 0.0307
Echinococcus granulosus rhodopsin orphan GPCR 0.0294 0.0465 0.046
Entamoeba histolytica cyclin family protein 0.0255 0.0392 0.1138
Echinococcus multilocularis cyclin B3 1 0.0255 0.0392 0.0388
Trichomonas vaginalis cyclin B, putative 0.0433 0.0721 0.2229
Giardia lamblia G2/mitotic-specific cyclin B 0.0433 0.0721 0.2229
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0145 0.0402
Onchocerca volvulus Neuropeptide F receptor homolog 0.0294 0.0465 0.1467
Echinococcus granulosus cyclin G2 0.0061 0.0036 0.0031
Schistosoma mansoni kinase 0.0072 0.0056 0.0052
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.016 0.0218 0.0213
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.1759 0.3166 0.3163
Schistosoma mansoni cyclin k 0.0061 0.0036 0.0031
Echinococcus multilocularis cyclin b3 0.0255 0.0392 0.0388
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Brugia malayi Melatonin receptor type 1A 0.0294 0.0465 0.046
Brugia malayi hypothetical protein 0.016 0.0218 0.0213
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Loa Loa (eye worm) G-protein coupled receptor 0.0294 0.0465 0.046
Trichomonas vaginalis cyclin B, putative 0.0433 0.0721 0.2229
Onchocerca volvulus 0.0923 0.1625 0.5133
Echinococcus multilocularis sodium and chloride dependent glycine 0.016 0.0218 0.0213
Trypanosoma brucei trypanothione reductase 0.0062 0.0037 0.0002
Giardia lamblia Cyclin fold protein 1, putative 0.0061 0.0036 0.0054
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.008 0.0071 0.0066
Brugia malayi casein kinase I 0.0065 0.0042 0.0037
Schistosoma mansoni biogenic amine receptor 0.0294 0.0465 0.046
Schistosoma mansoni amine GPCR 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.008 0.0071 0.0066
Brugia malayi Cyclin, N-terminal domain containing protein 0.0061 0.0036 0.0031
Onchocerca volvulus 0.016 0.0218 0.0687
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0158 0.0214 0.0673
Echinococcus granulosus BC026374 protein S09 family 0.0923 0.1625 0.1622
Echinococcus granulosus serotonin receptor 0.0294 0.0465 0.046
Echinococcus multilocularis thioredoxin glutathione reductase 0.0062 0.0037 0.0032
Brugia malayi putative neuropeptide receptor NPR1 0.0294 0.0465 0.046
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Echinococcus multilocularis serotonin receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) carboxylesterase 0.5465 1 1
Echinococcus multilocularis serotonin receptor 0.0294 0.0465 0.046
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.016 0.0218 0.0213
Echinococcus multilocularis neuropeptide Y receptor 0.0294 0.0465 0.046
Trypanosoma cruzi cyclin, putative 0.0433 0.0721 0.269
Trypanosoma cruzi casein kinase, putative 0.0065 0.0042 0.0157
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0073 0.0172
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0087 0.0084 0.0079
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.016 0.0218 0.0213
Onchocerca volvulus 0.0942 0.166 0.5242
Loa Loa (eye worm) cyclin domain-containing protein 0.0061 0.0036 0.0031
Loa Loa (eye worm) hypothetical protein 0.016 0.0218 0.0213
Echinococcus multilocularis somatostatin receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0081 0.0073 0.0068
Trypanosoma cruzi heat shock protein 85, putative 0.0052 0.0019 0.007
Echinococcus multilocularis casein kinase I alpha 0.0065 0.0042 0.0037
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Schistosoma mansoni biogenic amine (5HT) receptor 0.0294 0.0465 0.046
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0334 0.0539 0.1606
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.016 0.0218 0.0213
Schistosoma mansoni serine/threonine protein kinase 0.0553 0.0943 0.0939
Echinococcus multilocularis casein kinase I delta 0.0065 0.0042 0.0037
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Echinococcus granulosus casein kinase I alpha 0.0065 0.0042 0.0037
Entamoeba histolytica protein kinase, putative 0.0211 0.0312 0.0881
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0158 0.0214 0.0209
Trypanosoma cruzi cyclin 6, putative 0.0433 0.0721 0.269
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Loa Loa (eye worm) CYL-1 protein 0.0061 0.0036 0.0031
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0942 0.166 0.1656
Schistosoma mansoni amine GPCR 0.0294 0.0465 0.046
Leishmania major trypanothione reductase 0.0062 0.0037 0.0066
Giardia lamblia DNA repair protein RAD52 0.0334 0.0539 0.1651
Echinococcus granulosus casein kinase I alpha 0.0065 0.0042 0.0037
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.1053 0.1864 0.186
Schistosoma mansoni cyclin B3 0.1053 0.1864 0.186
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0603 0.1034 0.103
Trypanosoma cruzi heat shock protein 85, putative 0.0065 0.0043 0.0162
Brugia malayi Immunoglobulin I-set domain containing protein 0.0087 0.0084 0.0079
Trichomonas vaginalis spcc417.12 protein, putative 0.0923 0.1625 0.5104
Trichomonas vaginalis CK1 family protein kinase 0.0065 0.0042 0.0073
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0211 0.0312 0.0307
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0061 0.0036 0.0031
Brugia malayi hypothetical protein 0.0294 0.0465 0.046
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0081 0.0073 0.014
Echinococcus multilocularis cyclin dependent kinase 5 0.0553 0.0943 0.0939
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0294 0.0465 0.046
Brugia malayi hypothetical protein 0.0294 0.0465 0.046
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0294 0.0465 0.046
Plasmodium falciparum glycogen synthase kinase 3 0.1495 0.2679 1
Trichomonas vaginalis CMGC family protein kinase 0.1495 0.2679 0.8451
Echinococcus granulosus g protein coupled receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) norepinephrine transporter 0.0942 0.166 0.1656
Brugia malayi Cyclin, N-terminal domain containing protein 0.0061 0.0036 0.0031
Echinococcus granulosus 7TM GPCR rhodopsin 0.0294 0.0465 0.046
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0065 0.0042 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.0081 0.0073 0.0118
Brugia malayi intracellular kinase 0.1495 0.2679 0.2675
Loa Loa (eye worm) hypothetical protein 0.5465 1 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0294 0.0465 0.046
Brugia malayi Sodium:neurotransmitter symporter family protein 0.016 0.0218 0.0213
Echinococcus granulosus cyclin b3 0.0255 0.0392 0.0388
Leishmania major UDP-galactopyranose mutase 0.0158 0.0214 0.0734
Brugia malayi Cyclin, N-terminal domain containing protein 0.0061 0.0036 0.0031
Echinococcus granulosus cyclins 0.0255 0.0392 0.0388
Mycobacterium ulcerans dehydrogenase 0.0158 0.0214 0.0483
Echinococcus granulosus para nitrobenzyl esterase 0.0923 0.1625 0.1622
Echinococcus multilocularis rhodopsin orphan GPCR 0.0294 0.0465 0.046
Echinococcus granulosus sodium and chloride dependent glycine 0.016 0.0218 0.0213
Schistosoma mansoni hypothetical protein 0.0294 0.0465 0.046
Echinococcus multilocularis endoplasmin 0.0052 0.0019 0.0014
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.0134 0.013
Loa Loa (eye worm) hypothetical protein 0.0923 0.1625 0.1622
Echinococcus multilocularis G-protein coupled receptor, putative 0.0294 0.0465 0.046
Echinococcus granulosus biogenic amine 5HT receptor 0.0294 0.0465 0.046
Echinococcus multilocularis cyclin y 0.0061 0.0036 0.0031
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Mycobacterium tuberculosis Carboxylesterase LipT 0.0923 0.1625 0.4286
Echinococcus multilocularis casein kinase I alpha 0.0065 0.0042 0.0037
Echinococcus granulosus cyclins 0.0255 0.0392 0.0388
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Giardia lamblia Hypothetical protein 0.0255 0.0392 0.1186
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0061 0.0036 0.0031
Onchocerca volvulus 0.0294 0.0465 0.1467
Loa Loa (eye worm) hypothetical protein 0.0255 0.0394 0.0389
Trichomonas vaginalis cyclin B3, putative 0.0255 0.0392 0.1186
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0294 0.0465 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0145 0.0402
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.016 0.0218 0.0213
Trypanosoma brucei casein kinase I, isoform 2 0.0065 0.0042 0.0023
Leishmania major hypothetical protein, conserved 0.0542 0.0923 0.3398
Toxoplasma gondii hypothetical protein 0.0193 0.0279 0.0919
Giardia lamblia Kinase, CK1 Casein kinase 0.0065 0.0042 0.0073
Echinococcus granulosus G1:S specific cyclin D1 0.0061 0.0036 0.0031
Echinococcus granulosus acetylcholinesterase 0.5465 1 1
Echinococcus multilocularis allatostatin A receptor 0.0294 0.0465 0.046
Onchocerca volvulus 0.0294 0.0465 0.1467
Echinococcus multilocularis serotonin transporter 0.0942 0.166 0.1656
Echinococcus granulosus Immunoglobulin 0.008 0.0071 0.0066
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1495 0.2679 0.2675
Brugia malayi hypothetical protein 0.0294 0.0465 0.046
Plasmodium falciparum heat shock protein 90 0.0065 0.0043 0.0028
Loa Loa (eye worm) hypothetical protein 0.0188 0.027 0.0265
Brugia malayi Cyclin, N-terminal domain containing protein 0.0061 0.0036 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0054 0.0111
Brugia malayi Tachykinin-like peptides receptor 99D 0.0294 0.0465 0.046
Loa Loa (eye worm) cyclin domain-containing protein 0.1053 0.1864 0.186
Onchocerca volvulus 0.0294 0.0465 0.1467
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0553 0.0943 0.0939
Echinococcus multilocularis neuropeptide Y receptor 0.0294 0.0465 0.046
Trypanosoma brucei heat shock protein, putative 0.0065 0.0043 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0145 0.0141
Brugia malayi Dopamine receptor 0.0294 0.0465 0.046
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0081 0.0073 0.0272
Trypanosoma cruzi heat shock protein 85, putative 0.0065 0.0043 0.0162
Echinococcus granulosus cyclin dependent kinase 1 0.0553 0.0943 0.0939
Plasmodium vivax hypothetical protein, conserved 0.0158 0.0214 0.0673
Loa Loa (eye worm) acetylcholinesterase 1 0.5465 1 1
Loa Loa (eye worm) cyclin domain-containing protein 0.0061 0.0036 0.0031
Brugia malayi hypothetical protein 0.0061 0.0036 0.0031
Echinococcus granulosus biogenic amine 5HT receptor 0.0294 0.0465 0.046
Echinococcus granulosus carboxylesterase 5A 0.5465 1 1
Echinococcus multilocularis cyclins 0.0255 0.0392 0.0388
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0211 0.0312 0.1044
Echinococcus multilocularis neuropeptides capa receptor 0.0294 0.0465 0.046
Brugia malayi MH2 domain containing protein 0.0115 0.0134 0.013
Echinococcus multilocularis neuropeptide receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.016 0.0218 0.0213
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Brugia malayi hypothetical protein 0.0294 0.0465 0.046
Echinococcus granulosus endoplasmin 0.0052 0.0019 0.0014
Echinococcus granulosus lysine specific histone demethylase 1A 0.0158 0.0214 0.0209
Giardia lamblia Hypothetical protein 0.0061 0.0036 0.0054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0294 0.0465 0.046
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0294 0.0465 0.046
Schistosoma mansoni sodium/chloride dependent transporter 0.0942 0.166 0.1656
Loa Loa (eye worm) hypothetical protein 0.0178 0.0251 0.0247
Brugia malayi hypothetical protein 0.0294 0.0465 0.046
Echinococcus multilocularis neuroligin 0.0923 0.1625 0.1622
Echinococcus multilocularis cyclins 0.0255 0.0392 0.0388
Loa Loa (eye worm) hypothetical protein 0.0942 0.166 0.1656
Onchocerca volvulus 0.0923 0.1625 0.5133
Onchocerca volvulus 0.1759 0.3166 1
Echinococcus multilocularis G protein coupled receptor 139 0.0294 0.0465 0.046
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Echinococcus multilocularis protoporphyrinogen oxidase 0.0158 0.0214 0.0209
Trichomonas vaginalis cyclin A, putative 0.0433 0.0721 0.2229
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.1759 0.3166 1
Loa Loa (eye worm) hypothetical protein 0.0942 0.166 0.1656
Echinococcus multilocularis cyclin k 0.0061 0.0036 0.0031
Onchocerca volvulus 0.0065 0.0042 0.0133
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.1759 0.3166 1
Echinococcus granulosus dual specificity 0.0081 0.0073 0.0068
Echinococcus multilocularis neuropeptide receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Echinococcus multilocularis cyclin y 0.0061 0.0036 0.0031
Entamoeba histolytica protein kinase, putative 0.0081 0.0073 0.0118
Trypanosoma cruzi hypothetical protein, conserved 0.0542 0.0923 0.3444
Echinococcus multilocularis dual specificity 0.0081 0.0073 0.0068
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.016 0.0218 0.0687
Trichomonas vaginalis cyclin B3, putative 0.0061 0.0036 0.0054
Schistosoma mansoni neuropeptide F-like receptor 0.0294 0.0465 0.046
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.016 0.0218 0.0213
Schistosoma mansoni cell adhesion molecule 0.008 0.0071 0.0066
Schistosoma mansoni protein kinase 0.0065 0.0042 0.0037
Loa Loa (eye worm) cyclin domain-containing protein 0.0061 0.0036 0.0031
Brugia malayi Thioredoxin reductase 0.0062 0.0037 0.0032
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.016 0.0218 0.0213
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.016 0.0218 0.0213
Echinococcus granulosus uncharacterized sodium dependent transporter 0.016 0.0218 0.0213
Trichomonas vaginalis CK1 family protein kinase 0.0065 0.0042 0.0073
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.1759 0.3166 1
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0211 0.0312 0.1164
Schistosoma mansoni opsin-like receptor 0.0294 0.0465 0.046
Onchocerca volvulus 0.0294 0.0465 0.1467
Echinococcus granulosus heat shock protein 90 0.0065 0.0043 0.0039
Echinococcus granulosus tm gpcr rhodopsin 0.0294 0.0465 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0145 0.0402
Echinococcus multilocularis cyclin dependent kinase 1 0.0553 0.0943 0.0939
Brugia malayi Cyclin C 0.0061 0.0036 0.0031
Loa Loa (eye worm) cyclin domain-containing protein 0.0061 0.0036 0.0031
Brugia malayi Serotonin receptor 0.0294 0.0465 0.046
Echinococcus multilocularis cyclins 0.0255 0.0392 0.0388
Loa Loa (eye worm) hypothetical protein 0.0923 0.1625 0.1622
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Schistosoma mansoni myosin xvIII 0.0294 0.0465 0.046
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0507 0.0857 0.0852
Loa Loa (eye worm) melatonin receptor type 1A 0.0294 0.0465 0.046
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1495 0.2679 0.2675
Loa Loa (eye worm) hypothetical protein 0.0158 0.0214 0.0209
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0065 0.0042 0.0037
Brugia malayi glutathione reductase 0.0062 0.0037 0.0032
Echinococcus granulosus thioredoxin glutathione reductase 0.0062 0.0037 0.0032
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1495 0.2679 0.2675
Schistosoma mansoni hypothetical protein 0.0294 0.0465 0.046
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0081 0.0073 0.0203
Trypanosoma brucei heat shock protein, putative 0.0065 0.0043 0.0028
Entamoeba histolytica cyclin, putative 0.0255 0.0392 0.1138
Trypanosoma cruzi Heat shock protein 83, putative 0.0065 0.0043 0.0162
Mycobacterium tuberculosis Possible oxidoreductase 0.0158 0.0214 0.052
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Echinococcus granulosus cyclin dependent kinase 5 0.0553 0.0943 0.0939
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Echinococcus multilocularis g-protein coupled receptor 0.0294 0.0465 0.046
Brugia malayi hypothetical protein 0.0294 0.0465 0.046
Echinococcus granulosus casein kinase I alpha 0.0065 0.0042 0.0037
Loa Loa (eye worm) hypothetical protein 0.0923 0.1625 0.1622
Plasmodium vivax glycogen synthase kinase 3, putative 0.1495 0.2679 1
Schistosoma mansoni endoplasmin 0.0065 0.0043 0.0039
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Loa Loa (eye worm) hypothetical protein 0.0923 0.1625 0.1622
Plasmodium vivax protein kinase Crk2 0.0553 0.0943 0.3432
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0294 0.0465 0.046
Schistosoma mansoni cyclin B 0.0433 0.0721 0.0716
Echinococcus multilocularis cyclin dependent kinase 1 0.0553 0.0943 0.0939
Echinococcus granulosus sex peptide receptor 0.0294 0.0465 0.046
Plasmodium falciparum thioredoxin reductase 0.0062 0.0037 0.0002
Brugia malayi hypothetical protein 0.0294 0.0465 0.046
Trypanosoma cruzi mitotic cyclin, putative 0.0061 0.0036 0.0134
Echinococcus multilocularis g protein coupled receptor 0.0294 0.0465 0.046
Echinococcus multilocularis para nitrobenzyl esterase 0.0923 0.1625 0.1622
Toxoplasma gondii thioredoxin reductase 0.0062 0.0037 0.0002
Echinococcus multilocularis acetylcholinesterase 0.5465 1 1
Onchocerca volvulus 0.0294 0.0465 0.1467
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Loa Loa (eye worm) cyclin domain-containing protein 0.0061 0.0036 0.0031
Loa Loa (eye worm) hypothetical protein 0.0923 0.1625 0.1622
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.1759 0.3166 0.7791
Brugia malayi Carboxylesterase family protein 0.0923 0.1625 0.1622
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0294 0.0465 0.046
Brugia malayi RE15519p 0.0294 0.0465 0.046
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0635 0.1093 0.1089
Trichomonas vaginalis heat shock protein, putative 0.0065 0.0043 0.0078
Echinococcus multilocularis cyclin dependent kinase 0.0553 0.0943 0.0939
Giardia lamblia Cyclin B-like protein 0.0061 0.0036 0.0054
Brugia malayi neuropeptide F receptor 0.0294 0.0465 0.046
Echinococcus granulosus dual specificity 0.0081 0.0073 0.0068
Trypanosoma brucei Heat shock protein 83, putative 0.0065 0.0043 0.0028
Trypanosoma cruzi casein kinase, putative 0.0065 0.0042 0.0157
Plasmodium vivax amine transporter, putative 0.016 0.0218 0.0687
Onchocerca volvulus 0.0923 0.1625 0.5133
Entamoeba histolytica serine/threonine protein kinase, putative 0.0121 0.0145 0.0349
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Echinococcus multilocularis dual specificity 0.0081 0.0073 0.0068
Brugia malayi Carboxylesterase family protein 0.0923 0.1625 0.1622
Entamoeba histolytica cyclin, putative 0.0433 0.0721 0.2187
Trypanosoma brucei heat shock protein 90, putative 0.0065 0.0043 0.0028
Entamoeba histolytica heat shock protein 90, putative 0.0065 0.0043 0.0024
Plasmodium vivax endoplasmin, putative 0.0065 0.0043 0.0028
Leishmania major cyclin 0.0433 0.0721 0.2638
Mycobacterium ulcerans oxidoreductase 0.0158 0.0214 0.0483
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0533 0.0906 0.0902
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0433 0.0721 0.0716
Echinococcus granulosus allatostatin A receptor 0.0294 0.0465 0.046
Echinococcus multilocularis neuroglian 0.008 0.0071 0.0066
Echinococcus granulosus neuropeptide Y receptor 0.0294 0.0465 0.046
Onchocerca volvulus 0.016 0.0218 0.0687
Toxoplasma gondii heat shock protein 90, putative 0.0065 0.0043 0.0028
Entamoeba histolytica casein kinase, putative 0.0065 0.0042 0.0019
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Echinococcus multilocularis cyclin t1 0.0061 0.0036 0.0031
Echinococcus granulosus cyclin y 0.0061 0.0036 0.0031
Loa Loa (eye worm) hypothetical protein 0.016 0.0218 0.0213
Echinococcus multilocularis basement membrane specific heparan sulfate 0.008 0.0071 0.0066
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0553 0.0943 0.0939
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.2243 0.4059 1
Schistosoma mansoni sodium-dependent amino acid transporter 0.016 0.0218 0.0213
Echinococcus granulosus cyclin t1 0.0061 0.0036 0.0031
Schistosoma mansoni neuropeptide f receptor 76f 0.0294 0.0465 0.046
Brugia malayi serine/threonine-protein kinase plk-2 0.0121 0.0145 0.0141
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Echinococcus granulosus heat shock protein 0.0065 0.0043 0.0039
Echinococcus granulosus tachykinin peptides receptor 99D 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.008 0.0071 0.0066
Schistosoma mansoni neuropeptide receptor 0.0294 0.0465 0.046
Trypanosoma cruzi hypothetical protein, conserved 0.0061 0.0036 0.0134
Schistosoma mansoni cyclins 0.0255 0.0392 0.0388
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.016 0.0218 0.0213
Trypanosoma cruzi heat shock protein 85, putative 0.0065 0.0043 0.0162
Schistosoma mansoni neuroligin 3 (S09 family) 0.0923 0.1625 0.1622
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Brugia malayi Carboxylesterase family protein 0.5465 1 1
Echinococcus granulosus neuropeptides capa receptor 0.0294 0.0465 0.046
Brugia malayi hypothetical protein 0.0294 0.0465 0.046
Brugia malayi Sodium:neurotransmitter symporter family protein 0.016 0.0218 0.0213
Echinococcus multilocularis cyclin G2 0.0061 0.0036 0.0031
Loa Loa (eye worm) hypothetical protein 0.0533 0.0906 0.0902
Echinococcus granulosus uncharacterized sodium dependent transporter 0.016 0.0218 0.0213
Loa Loa (eye worm) hypothetical protein 0.016 0.0218 0.0213
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0433 0.0721 0.0716
Schistosoma mansoni cyclin l 0.0061 0.0036 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0294 0.0465 0.046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0294 0.0465 0.046
Echinococcus multilocularis casein kinase i 0.0065 0.0042 0.0037
Giardia lamblia Cyclin A 0.0255 0.0392 0.1186
Trypanosoma cruzi cyclin, putative 0.0433 0.0721 0.269
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.016 0.0218 0.0687
Loa Loa (eye worm) hypothetical protein 0.0158 0.0214 0.0209
Trypanosoma cruzi cyclin 9, putative 0.0061 0.0036 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.0553 0.0943 0.2936
Brugia malayi Cyclin, N-terminal domain containing protein 0.1053 0.1864 0.186
Echinococcus granulosus serotonin transporter 0.0942 0.166 0.1656
Leishmania major mitotic cyclin, putative 0.0061 0.0036 0.0064
Echinococcus granulosus neuropeptide s receptor 0.0294 0.0465 0.046
Schistosoma mansoni amine GPCR 0.0758 0.1321 0.1317
Echinococcus granulosus 7tm_1 domain containing protein 0.0294 0.0465 0.046
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0158 0.0214 0.0673
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0211 0.0312 0.1164
Entamoeba histolytica protein tyrosine phosphatase, putative 0.1759 0.3166 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0294 0.0465 0.046
Trichomonas vaginalis CMGC family protein kinase 0.0553 0.0943 0.2936
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0294 0.0465 0.046
Echinococcus granulosus rhodopsin orphan GPCR 0.0294 0.0465 0.046
Plasmodium vivax casein kinase 1, putative 0.0065 0.0042 0.0023
Schistosoma mansoni hypothetical protein 0.0061 0.0036 0.0031
Brugia malayi Dopamine receptor protein 2 0.0294 0.0465 0.046
Plasmodium vivax heat shock protein 86, putative 0.0065 0.0043 0.0028
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0158 0.0214 0.0673
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.5465 1 1
Onchocerca volvulus Cyclin L homolog 0.0061 0.0036 0.0114
Schistosoma mansoni gliotactin 0.0923 0.1625 0.1622
Trichomonas vaginalis cyclins, putative 0.024 0.0364 0.1098
Echinococcus multilocularis cyclin B 0.0433 0.0721 0.0716
Loa Loa (eye worm) hypothetical protein 0.008 0.0071 0.0066
Schistosoma mansoni opsin-like receptor 0.0294 0.0465 0.046
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0294 0.0465 0.046
Entamoeba histolytica protein kinase domain containing protein 0.1495 0.2679 0.8442
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0036 0.0054
Loa Loa (eye worm) hypothetical protein 0.0158 0.0214 0.0209
Giardia lamblia Kinase, CMGC DYRK 0.0081 0.0073 0.0172
Loa Loa (eye worm) hypothetical protein 0.5465 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0294 0.0465 0.046
Echinococcus granulosus cyclin y 0.0061 0.0036 0.0031
Loa Loa (eye worm) thioredoxin reductase 0.0062 0.0037 0.0032
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Echinococcus multilocularis heat shock protein 0.0065 0.0043 0.0039
Onchocerca volvulus 0.016 0.0218 0.0687
Brugia malayi Fibronectin type III domain containing protein 0.008 0.0071 0.0066
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0081 0.0073 0.014
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.1759 0.3166 1
Brugia malayi sulfakinin receptor protein 0.0294 0.0465 0.046
Trichomonas vaginalis cyclin B, putative 0.0061 0.0036 0.0054
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.016 0.0218 0.0213
Schistosoma mansoni g1/s-specific cyclin C 0.0061 0.0036 0.0031
Echinococcus multilocularis cyclins 0.0255 0.0392 0.0388
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Trypanosoma brucei cdc2-related kinase 3 0.0553 0.0943 0.3432
Plasmodium falciparum protoporphyrinogen oxidase 0.0158 0.0214 0.0673
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0294 0.0465 0.046
Toxoplasma gondii casein kinase I 0.0065 0.0042 0.0023
Echinococcus granulosus neuropeptide Y receptor 0.0294 0.0465 0.046
Entamoeba histolytica hypothetical protein 0.0211 0.0312 0.0881
Schistosoma mansoni histamine h1 receptor 0.0294 0.0465 0.046
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1495 0.2679 1
Schistosoma mansoni cyclin G 0.0061 0.0036 0.0031
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0923 0.1625 0.1622
Echinococcus multilocularis fmrfamide receptor 0.0294 0.0465 0.046
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0542 0.0923 0.2871
Loa Loa (eye worm) hypothetical protein 0.0942 0.166 0.1656
Plasmodium vivax glutathione reductase, putative 0.0062 0.0037 0.0002
Echinococcus granulosus neuropeptide FF receptor 2 0.0294 0.0465 0.046
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0036 0.0054
Loa Loa (eye worm) G-protein coupled receptor 0.0294 0.0465 0.046
Echinococcus granulosus casein kinase i 0.0065 0.0042 0.0037
Brugia malayi Cyclin, N-terminal domain containing protein 0.0433 0.0721 0.0716
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0052 0.0019 0.0014
Echinococcus granulosus neuropeptide receptor A26 0.0294 0.0465 0.046
Echinococcus multilocularis orexin receptor type 2 0.0294 0.0465 0.046
Trichomonas vaginalis cyclin D, putative 0.0255 0.0392 0.1186
Loa Loa (eye worm) hypothetical protein 0.07 0.1213 0.1209
Plasmodium vivax hypothetical protein, conserved 0.016 0.0218 0.0687
Trichomonas vaginalis cyclins, putative 0.0433 0.0721 0.2229
Brugia malayi Protein kinase domain containing protein 0.0553 0.0943 0.0939
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Echinococcus granulosus lysine specific histone demethylase 1A 0.0158 0.0214 0.0209
Brugia malayi G-protein coupled receptor 0.0294 0.0465 0.046
Echinococcus granulosus G protein coupled receptor 139 0.0294 0.0465 0.046
Schistosoma mansoni hypothetical protein 0.0294 0.0465 0.046
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1495 0.2679 1
Brugia malayi G-protein coupled receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0188 0.027 0.0265
Onchocerca volvulus 0.0433 0.0721 0.2276
Onchocerca volvulus Protein CNPPD1 homolog 0.0061 0.0036 0.0114
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0923 0.1625 0.1622
Echinococcus multilocularis protein kinase shaggy 0.1495 0.2679 0.2675
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0553 0.0943 0.0939
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0294 0.0465 0.046
Onchocerca volvulus 0.0294 0.0465 0.1467
Echinococcus multilocularis cyclins 0.0255 0.0392 0.0388
Brugia malayi Carboxylesterase family protein 0.0923 0.1625 0.1622
Brugia malayi Immunoglobulin I-set domain containing protein 0.008 0.0071 0.0066
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.1759 0.3166 1
Echinococcus granulosus acetylcholinesterase 0.5465 1 1
Brugia malayi cyclin fold protein 1 variant b 0.0061 0.0036 0.0031
Brugia malayi hypothetical protein 0.0923 0.1625 0.1622
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0923 0.1625 0.1622
Echinococcus multilocularis heat shock protein 90 0.0052 0.0019 0.0014
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0158 0.0214 0.0209
Trypanosoma cruzi CYC2-like cyclin, putative 0.0433 0.0721 0.269
Brugia malayi Serotonin receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.008 0.0071 0.0066
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.008 0.0071 0.0066
Echinococcus granulosus cyclin k 0.0061 0.0036 0.0031
Plasmodium vivax thioredoxin reductase, putative 0.0062 0.0037 0.0002
Trichomonas vaginalis cyclin B, putative 0.0433 0.0721 0.2229
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0294 0.0465 0.046
Echinococcus multilocularis sex peptide receptor 0.0294 0.0465 0.046
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.2243 0.4059 1
Echinococcus granulosus tm gpcr rhodopsin 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Echinococcus multilocularis g protein coupled receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.016 0.0218 0.0213
Echinococcus granulosus casein kinase I delta 0.0065 0.0042 0.0037
Echinococcus granulosus neuropeptide receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Entamoeba histolytica protein kinase, putative 0.1495 0.2679 0.8442
Loa Loa (eye worm) hypothetical protein 0.008 0.0071 0.0066
Schistosoma mansoni neuropeptide F-like receptor 0.0294 0.0465 0.046
Echinococcus multilocularis acetylcholinesterase 0.5465 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0073 0.0172
Loa Loa (eye worm) hypothetical protein 0.0923 0.1625 0.1622
Echinococcus multilocularis fmrfamide receptor 0.0294 0.0465 0.046
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0211 0.0312 0.1102
Mycobacterium ulcerans monoamine oxidase 0.0158 0.0214 0.0483
Trichomonas vaginalis cyclins, putative 0.0061 0.0036 0.0054
Schistosoma mansoni acetylcholinesterase 0.0923 0.1625 0.1622
Trypanosoma cruzi cdc2-related kinase 1 0.0553 0.0943 0.352
Onchocerca volvulus 0.0294 0.0465 0.1467
Echinococcus multilocularis rhodopsin orphan GPCR 0.0294 0.0465 0.046
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0294 0.0465 0.046
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0095 0.0098 0.0198
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0065 0.0042 0.0037
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Brugia malayi Protein kinase domain containing protein 0.0211 0.0312 0.0307
Echinococcus granulosus cyclin A3 4 0.0061 0.0036 0.0031
Echinococcus multilocularis BC026374 protein (S09 family) 0.0923 0.1625 0.1622
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.1759 0.3166 0.3163
Echinococcus granulosus g-protein coupled receptor 0.0294 0.0465 0.046
Entamoeba histolytica protein kinase domain containing protein 0.1495 0.2679 0.8442
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.2085 0.3768 1
Trichomonas vaginalis cyclin B, putative 0.0255 0.0392 0.1186
Loa Loa (eye worm) hypothetical protein 0.016 0.0218 0.0213
Schistosoma mansoni heat shock protein 0.0065 0.0043 0.0039
Echinococcus multilocularis casein kinase I alpha 0.0065 0.0042 0.0037
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0158 0.0214 0.0209
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0294 0.0465 0.046
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0061 0.0036 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Echinococcus granulosus rhodopsin orphan GPCR 0.0294 0.0465 0.046
Loa Loa (eye worm) TYRA-2 protein 0.0294 0.0465 0.046
Leishmania major heat shock protein 83-1 0.0065 0.0043 0.0092
Trypanosoma cruzi trypanothione reductase, putative 0.0062 0.0037 0.0136
Echinococcus multilocularis neuropeptide s receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.008 0.0071 0.0066
Onchocerca volvulus 0.0294 0.0465 0.1467
Toxoplasma gondii hypothetical protein 0.016 0.0218 0.0687
Loa Loa (eye worm) hypothetical protein 0.008 0.0071 0.0066
Trypanosoma cruzi UDP-galactopyranose mutase 0.0158 0.0214 0.0799
Loa Loa (eye worm) hypothetical protein 0.0158 0.0214 0.0209
Toxoplasma gondii heat shock protein HSP90 0.0065 0.0043 0.0028
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.016 0.0218 0.0213
Schistosoma mansoni endoplasmin 0.0065 0.0043 0.0039
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0158 0.0214 0.0483
Toxoplasma gondii hypothetical protein 0.016 0.0218 0.0687
Echinococcus granulosus dro:myosuppressin receptor 0.0294 0.0465 0.046
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.016 0.0218 0.0213
Echinococcus granulosus cyclins 0.0061 0.0036 0.0031
Echinococcus granulosus Cyclin L1 0.0061 0.0036 0.0031
Echinococcus multilocularis dro:myosuppressin receptor 0.0294 0.0465 0.046
Echinococcus granulosus cyclin G2 0.0061 0.0036 0.0031
Schistosoma mansoni amine GPCR 0.0294 0.0465 0.046
Echinococcus multilocularis 0.0158 0.0214 0.0209
Trypanosoma cruzi heat shock protein 90, putative 0.0065 0.0043 0.0162
Schistosoma mansoni alpha-1 adrenergic receptor 0.0294 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Trichomonas vaginalis CMGC family protein kinase 0.0081 0.0073 0.0172
Treponema pallidum sodium- and chloride- dependent transporter 0.0942 0.166 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0294 0.0465 0.046
Leishmania major cyclin 9, putative 0.0061 0.0036 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0145 0.0402
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0145 0.0402
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.016 0.0218 0.0213
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0061 0.0036 0.0031
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0553 0.0943 0.3432
Brugia malayi Carboxylesterase family protein 0.0923 0.1625 0.1622
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0036 0.0054
Schistosoma mansoni BC026374 protein (S09 family) 0.0923 0.1625 0.1622
Echinococcus granulosus neuroligin 0.0923 0.1625 0.1622
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1495 0.2679 0.2675
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0294 0.0465 0.046
Onchocerca volvulus 0.0294 0.0465 0.1467
Trypanosoma brucei protein kinase, putative 0.1495 0.2679 1
Brugia malayi hypothetical protein 0.0158 0.0214 0.0209
Echinococcus multilocularis dual specificity 0.0081 0.0073 0.0068
Loa Loa (eye worm) hypothetical protein 0.0294 0.0465 0.046
Entamoeba histolytica protein kinase, putative 0.0211 0.0312 0.0881
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0312 0.0307

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 62 nM Inhibition of MCH-mediated calcium release by CHO cells expressing human MCH-R1 ChEMBL. 16879961
IC50 (functional) = 62 nM Inhibition of MCH-mediated calcium release by CHO cells expressing human MCH-R1 ChEMBL. 16879961
Ki (binding) = 27 nM Binding activity against human MCH-R1 ChEMBL. 16879961
Ki (binding) = 27 nM Binding activity against human MCH-R1 ChEMBL. 16879961

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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