Detailed information for compound 419945

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 468.587 | Formula: C30H32N2O3
  • H donors: 2 H acceptors: 2 LogP: 3.85 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCn1cc(c2c1[C@@H]1Oc3c4[C@@]51[C@](C2)(O)C(Cc4ccc3O)N(CC5)CC1CC1)c1ccccc1
  • InChi: 1S/C30H32N2O3/c1-2-31-17-22(19-6-4-3-5-7-19)21-15-30(34)24-14-20-10-11-23(33)27-25(20)29(30,28(35-27)26(21)31)12-13-32(24)16-18-8-9-18/h3-7,10-11,17-18,24,28,33-34H,2,8-9,12-16H2,1H3/t24?,28-,29-,30+/m0/s1
  • InChiKey: ZJCRMGAAPIMSFZ-JYBLDVITSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens opioid receptor, mu 1 Starlite/ChEMBL References
Homo sapiens opioid receptor, kappa 1 Starlite/ChEMBL References
Homo sapiens opioid receptor, delta 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Get druggable targets OG5_139759 All targets in OG5_139759
Echinococcus granulosus tm gpcr rhodopsin Get druggable targets OG5_139759 All targets in OG5_139759

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Schistosoma mansoni protein kinase 0.0066 0.0102 0.0102
Brugia malayi bone morphogenetic protein type 1 receptor 0.0049 0.0028 0.0028
Schistosoma mansoni tyrosine kinase 0.0072 0.0129 0.0129
Entamoeba histolytica receptor protein kinase, putative 0.0049 0.0028 0.005
Echinococcus granulosus protein kinase shaggy 0.0156 0.0505 0.0505
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0174 0.0585 0.0585
Schistosoma mansoni atypical protein kinase C 0.0064 0.0095 0.0095
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0244 0.09 0.09
Trypanosoma brucei Pseudokinase, putative 0.0049 0.0028 0.005
Loa Loa (eye worm) TK protein kinase 0.0257 0.0956 0.0956
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0244 0.09 0.09
Entamoeba histolytica protein kinase domain containing protein 0.0156 0.0505 0.0888
Brugia malayi Protein kinase c protein 2 0.0064 0.0092 0.0092
Echinococcus granulosus epidermal growth factor receptor 0.0449 0.1813 0.1813
Echinococcus granulosus tyrosine protein kinase csk 0.0049 0.0028 0.0028
Loa Loa (eye worm) cyclin domain-containing protein 0.0174 0.0585 0.0585
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.006 0.0074 0.0074
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.033 0.1281 0.2253
Echinococcus multilocularis cyclins 0.07 0.2934 0.2934
Toxoplasma gondii AGC kinase 0.0124 0.0363 0.1685
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0348 0.1363 0.1363
Schistosoma mansoni ephrin receptor 0.0049 0.0028 0.0028
Leishmania major cyclin 0.1316 0.5687 1
Brugia malayi hypothetical protein 0.0174 0.0585 0.0585
Schistosoma mansoni tyrosine kinase 0.0316 0.1218 0.1218
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0049 0.0028 0.0028
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0156 0.0505 0.0505
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.1316 0.5687 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.0326 0.0326
Trypanosoma brucei protein kinase, putative 0.0156 0.0505 0.0888
Echinococcus granulosus hypothetical protein 0.006 0.0076 0.0076
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0066 0.0102 0.0102
Schistosoma mansoni cyclin k 0.0174 0.0585 0.0585
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0377 0.0664
Brugia malayi Cyclin, N-terminal domain containing protein 0.0174 0.0585 0.0585
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Brugia malayi cyclin-dependent kinase 9 0.0064 0.0092 0.0092
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.011 0.0301 0.0529
Plasmodium falciparum tyrosine kinase-like protein 0.0049 0.0028 0.0097
Plasmodium vivax cyclin 4, putative 0.0174 0.0585 0.2995
Entamoeba histolytica ankyrin repeat protein 0.0049 0.0028 0.005
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0068 0.012
Onchocerca volvulus 0.0127 0.0377 0.0617
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0095 0.0231 0.1182
Trichomonas vaginalis cyclins, putative 0.07 0.2934 0.5159
Echinococcus multilocularis tyrosine protein kinase HCK 0.0049 0.0028 0.0028
Entamoeba histolytica serine/threonine kinase, putative 0.0049 0.0028 0.005
Echinococcus multilocularis cyclin dependent kinase 5 0.048 0.1954 0.1954
Echinococcus granulosus tyrosine kinase 0.0049 0.0028 0.0028
Echinococcus multilocularis cyclin dependent kinase 0.048 0.1954 0.1954
Trichomonas vaginalis cyclins, putative 0.0174 0.0585 0.1029
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus granulosus neuroglian 0.0099 0.025 0.025
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0178 0.0601 0.0601
Brugia malayi serine/threonine-protein kinase plk-2 0.0244 0.09 0.09
Brugia malayi hypothetical protein 0.0049 0.0028 0.0028
Echinococcus granulosus activated cdc42 kinase 1 0.0049 0.0028 0.0028
Trichomonas vaginalis cyclins, putative 0.1316 0.5687 1
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.0585 0.1029
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0049 0.0028 0.0028
Entamoeba histolytica cyclin, domain containing protein 0.0174 0.0585 0.1029
Echinococcus multilocularis tyrosine protein kinase Abl 0.0149 0.0476 0.0476
Entamoeba histolytica tyrosin kinase, putative 0.0049 0.0028 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0106 0.0106
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0028 0.0028
Loa Loa (eye worm) TK/CSK protein kinase 0.0049 0.0028 0.0028
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0068 0.0068
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0058 0.0068 0.0068
Schistosoma mansoni cyclin G 0.0174 0.0585 0.0585
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0082 0.0173 0.0173
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0156 0.0505 0.0505
Loa Loa (eye worm) TK protein kinase 0.0049 0.0028 0.0028
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Loa Loa (eye worm) hypothetical protein 0.006 0.0076 0.0076
Brugia malayi Fibronectin type III domain containing protein 0.0082 0.0173 0.0173
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Schistosoma mansoni tyrosine kinase 0.0316 0.1218 0.1218
Toxoplasma gondii hypothetical protein 0.0174 0.0585 0.2714
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0072 0.0129 0.0129
Trypanosoma brucei polo-like protein kinase 0.0244 0.09 0.1582
Onchocerca volvulus 0.006 0.0074 0.0081
Loa Loa (eye worm) phosphatidylinositol 3 0.0101 0.0257 0.0257
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0066 0.0102 0.0102
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0077 0.0153 0.022
Echinococcus granulosus G2:mitotic specific cyclin B3 0.2282 1 1
Loa Loa (eye worm) cyclin domain-containing protein 0.0174 0.0585 0.0585
Echinococcus granulosus ephrin type A receptor 4 A 0.0049 0.0028 0.0028
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Echinococcus granulosus integrin linked protein kinase 0.0049 0.0028 0.0028
Brugia malayi hypothetical protein 0.0082 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Echinococcus multilocularis protein kinase shaggy 0.0156 0.0505 0.0505
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0049 0.0028 0.0028
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.006 0.0074 0.0074
Echinococcus granulosus insulin receptor 0.0391 0.1553 0.1553
Plasmodium falciparum protein kinase, putative 0.0066 0.0102 0.0346
Trichomonas vaginalis cyclins, putative 0.1316 0.5687 1
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0068 0.0068
Trichomonas vaginalis CMGC family protein kinase 0.048 0.1954 0.3436
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Echinococcus multilocularis cyclin dependent kinase 9 0.0064 0.0092 0.0092
Echinococcus granulosus cyclins 0.07 0.2934 0.2934
Onchocerca volvulus Serine\/threonine kinase homolog 0.0244 0.09 0.154
Schistosoma mansoni hypothetical protein 0.0049 0.0028 0.0028
Echinococcus multilocularis c src tyrosine kinase 0.0072 0.0129 0.0129
Trypanosoma brucei mitotic cyclin 0.0174 0.0585 0.1029
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0049 0.0028 0.0028
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0078 0.0158 0.0158
Trypanosoma cruzi Protein kinase B 0.0088 0.02 0.0351
Loa Loa (eye worm) hypothetical protein 0.0436 0.1755 0.1755
Schistosoma mansoni protein kinase 0.0049 0.0028 0.0028
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0095 0.0231 0.0406
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0049 0.0028 0.0028
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0076 0.0149 0.0263
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0102 0.0179
Giardia lamblia Kinase, CDC7 0.0127 0.0377 0.0617
Loa Loa (eye worm) RGC/RGC protein kinase 0.0049 0.0028 0.0028
Onchocerca volvulus 0.006 0.0074 0.0081
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Leishmania major mitotic cyclin, putative 0.0174 0.0585 0.1029
Echinococcus multilocularis tyrosine protein kinase Fyn 0.006 0.0074 0.0074
Echinococcus granulosus cyclin G2 0.0174 0.0585 0.0585
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0108 0.019
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0105 0.0279 0.0279
Echinococcus granulosus protein kinase 0.0134 0.0406 0.0406
Echinococcus multilocularis transfer RNA-Thr 0.0049 0.0028 0.0028
Echinococcus granulosus active breakpoint cluster region 0.01 0.0253 0.0253
Brugia malayi Protein kinase domain containing protein 0.006 0.0074 0.0074
Echinococcus multilocularis receptor type guanylyl cyclase 0.0049 0.0028 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.0156 0.0505 0.0888
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0156 0.0505 0.0505
Brugia malayi Protein kinase domain containing protein 0.0067 0.0108 0.0108
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0066 0.0102 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0092 0.0092
Trichomonas vaginalis cyclins, putative 0.079 0.3339 0.5871
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0028 0.0028
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0028 0.0028
Brugia malayi Hr1 repeat family protein 0.0058 0.0068 0.0068
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0049 0.0028 0.0028
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.011 0.0301 0.0529
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0049 0.0028 0.0028
Echinococcus granulosus tyrosine protein kinase Btk29A 0.02 0.0702 0.0702
Trypanosoma cruzi protein kinase, putative 0.0049 0.0028 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0028 0.0028
Schistosoma mansoni Cyclin fold protein 0.0174 0.0585 0.0585
Echinococcus multilocularis cyclin dependent kinase 1 0.048 0.1954 0.1954
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus granulosus tyrosine protein kinase shark 0.006 0.0074 0.0074
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0058 0.0068 0.0068
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0072 0.0129 0.0129
Loa Loa (eye worm) TK protein kinase 0.0049 0.0028 0.0028
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0049 0.0028 0.0028
Schistosoma mansoni cyclin d 0.0174 0.0585 0.0585
Schistosoma mansoni rap gtpase-activating protein 0.0049 0.0028 0.0028
Giardia lamblia Cyclin A 0.07 0.2934 0.5134
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Giardia lamblia Cyclin fold protein 1, putative 0.0174 0.0585 0.0984
Loa Loa (eye worm) CYL-1 protein 0.0174 0.0585 0.0585
Echinococcus granulosus dual specificity 0.011 0.0299 0.0299
Trichomonas vaginalis TK family protein kinase 0.0049 0.0028 0.005
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0088 0.02 0.0351
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0095 0.0231 0.0231
Onchocerca volvulus Protein CNPPD1 homolog 0.0174 0.0585 0.0984
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.005 0.0033 0.0033
Brugia malayi cyclin fold protein 1 variant b 0.0174 0.0585 0.0585
Echinococcus multilocularis integrin linked protein kinase 0.0049 0.0028 0.0028
Schistosoma mansoni tyrosine kinase 0.0252 0.0934 0.0934
Plasmodium falciparum glycogen synthase kinase 3 0.0156 0.0505 0.1721
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0076 0.0149 0.0149
Entamoeba histolytica tyrosin kinase, putative 0.0049 0.0028 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0244 0.09 0.1582
Echinococcus granulosus roundabout 2 0.0116 0.0326 0.0326
Leishmania major protein kinase, putative 0.0049 0.0028 0.005
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.033 0.1281 0.2253
Schistosoma mansoni tyrosine kinase 0.0072 0.0129 0.0129
Brugia malayi Tyrosine-protein kinase abl-1 0.0125 0.0368 0.0368
Trichomonas vaginalis AGC family protein kinase 0.013 0.0387 0.068
Echinococcus granulosus tyrosine protein kinase Fyn 0.0072 0.0129 0.0129
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0066 0.0102 0.0179
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0058 0.0068 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0108 0.019
Loa Loa (eye worm) hypothetical protein 0.0616 0.2562 0.2562
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Trypanosoma cruzi cyclin 6, putative 0.1316 0.5687 1
Echinococcus multilocularis ephrin type A receptor 4 A 0.0049 0.0028 0.0028
Entamoeba histolytica hypothetical protein 0.0174 0.0585 0.1029
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0049 0.0028 0.0028
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0092 0.0162
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.005
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0156 0.0505 0.0888
Trichomonas vaginalis cyclin B, putative 0.1316 0.5687 1
Trypanosoma brucei cyclin 3 0.0174 0.0585 0.1029
Echinococcus multilocularis neuroglian 0.0099 0.025 0.025
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0049 0.0028 0.0028
Entamoeba histolytica cyclin family protein 0.07 0.2934 0.5159
Trichomonas vaginalis cyclin B, putative 0.1316 0.5687 1
Echinococcus granulosus cyclin dependent kinase 1 0.048 0.1954 0.1954
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0105 0.0185
Echinococcus multilocularis tyrosine kinase 0.0049 0.0028 0.0028
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.006 0.0074 0.0074
Schistosoma mansoni protein kinase 0.0049 0.0028 0.0028
Entamoeba histolytica protein kinase, putative 0.013 0.0387 0.068
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis cyclin D, putative 0.0174 0.0585 0.1029
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0092 0.0162
Echinococcus granulosus tyrosine protein kinase Src64B 0.0072 0.0129 0.0129
Echinococcus multilocularis serine:threonine protein kinase N2 0.0058 0.0068 0.0068
Echinococcus multilocularis cyclin dependent kinase 1 0.048 0.1954 0.1954
Loa Loa (eye worm) cyclin domain-containing protein 0.0174 0.0585 0.0585
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0095 0.0231 0.0406
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase, putative 0.013 0.0387 0.068
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0049 0.0028 0.0028
Entamoeba histolytica cyclin, domain containing protein 0.0174 0.0585 0.1029
Loa Loa (eye worm) hypothetical protein 0.0082 0.0173 0.0173
Schistosoma mansoni tyrosine kinase 0.006 0.0074 0.0074
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0231 0.0231
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.005
Echinococcus granulosus Immunoglobulin 0.0082 0.0173 0.0173
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0049 0.0028 0.0028
Echinococcus multilocularis cyclin A3 4 0.0174 0.0585 0.0585
Loa Loa (eye worm) hypothetical protein 0.0129 0.0384 0.0384
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0066 0.0102 0.0179
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0066 0.0105 0.0105
Schistosoma mansoni protein tyrosine kinase 0.0049 0.0028 0.0028
Plasmodium vivax cyclin homologue, putative 0.0174 0.0585 0.2995
Trypanosoma brucei rac serine-threonine kinase, putative 0.013 0.0387 0.068
Trichomonas vaginalis cyclins, putative 0.0174 0.0585 0.1029
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Brugia malayi Protein kinase domain containing protein 0.011 0.0299 0.0299
Trypanosoma brucei protein kinase, putative 0.0066 0.0102 0.0179
Plasmodium vivax glycogen synthase kinase 3, putative 0.0156 0.0505 0.2584
Echinococcus granulosus cyclin A3 4 0.0174 0.0585 0.0585
Leishmania major protein kinase, putative 0.0066 0.0102 0.0179
Loa Loa (eye worm) AGC/PKN protein kinase 0.0058 0.0068 0.0068
Loa Loa (eye worm) TK protein kinase 0.0049 0.0028 0.0028
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0058 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0072 0.0129 0.0129
Loa Loa (eye worm) TK/FAK protein kinase 0.0049 0.0028 0.0028
Entamoeba histolytica tyrosin kinase, putative 0.0052 0.0042 0.0074
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0049 0.0028 0.0028
Echinococcus multilocularis Glutaredoxin protein 5 0.0066 0.0103 0.0103
Loa Loa (eye worm) TK/FER protein kinase 0.006 0.0074 0.0074
Onchocerca volvulus 0.0174 0.0585 0.0984
Schistosoma mansoni tyrosine kinase 0.0266 0.0997 0.0997
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Schistosoma mansoni tyrosine kinase 0.024 0.0879 0.0879
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Echinococcus multilocularis cyclin 0.0174 0.0585 0.0585
Echinococcus multilocularis tyrosine protein kinase csk 0.0049 0.0028 0.0028
Entamoeba histolytica cell division protein kinase 2, putative 0.048 0.1954 0.3436
Entamoeba histolytica ankyrin repeat protein 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Trypanosoma cruzi CYC2-like cyclin, putative 0.1316 0.5687 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0127 0.0375 0.0375
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0075 0.0145 0.0145
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0174 0.0585 0.2714
Brugia malayi C-terminal src kinase protein 1 0.0049 0.0028 0.0028
Echinococcus multilocularis nervana 2 0.0066 0.0103 0.0103
Echinococcus multilocularis natriuretic peptide receptor 1 0.0049 0.0028 0.0028
Echinococcus multilocularis cyclin B3 1 0.07 0.2934 0.2934
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0316 0.1218 0.1218
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0076 0.0149 0.0263
Brugia malayi Raf kinase 0.0049 0.0028 0.0028
Echinococcus granulosus dual specificity protein kinase clk2 0.0076 0.0149 0.0149
Loa Loa (eye worm) TK/FER protein kinase 0.006 0.0074 0.0074
Plasmodium falciparum cyclin 1 0.0174 0.0585 0.1995
Echinococcus granulosus cyclin dependent kinase 0.048 0.1954 0.1954
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0156 0.0505 0.2342
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0067 0.0106 0.0106
Echinococcus multilocularis cyclins 0.07 0.2934 0.2934
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Loa Loa (eye worm) hypothetical protein 0.0095 0.0231 0.0231
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0049 0.0028 0.0028
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.033 0.1281 0.1281
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Giardia lamblia G2/mitotic-specific cyclin B 0.1316 0.5687 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.0174 0.0585 0.0585
Toxoplasma gondii protein kinase domain-containing protein 0.0049 0.0028 0.0131
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0482 0.1963 0.1963
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Echinococcus granulosus tyrosine protein kinase Src42A 0.0072 0.0129 0.0129
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trypanosoma cruzi cyclin 9, putative 0.0174 0.0585 0.1029
Toxoplasma gondii STE kinase 0.0049 0.0028 0.0131
Brugia malayi Protein kinase domain containing protein 0.0058 0.0068 0.0068
Toxoplasma gondii AGC kinase 0.0095 0.0231 0.1071
Echinococcus multilocularis serine:threonine protein kinase N2 0.0058 0.0068 0.0068
Loa Loa (eye worm) TK/EPH protein kinase 0.0049 0.0028 0.0028
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0113 0.0312 0.0312
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0049 0.0028 0.005
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0482 0.1963 0.1963
Echinococcus granulosus retinal guanylyl cyclase 2 0.0049 0.0028 0.0028
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0049 0.0028 0.0028
Trichomonas vaginalis cyclin B3, putative 0.07 0.2934 0.5159
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0028 0.0028
Brugia malayi Protein kinase domain containing protein 0.048 0.1954 0.1954
Brugia malayi Cyclin, N-terminal domain containing protein 0.1316 0.5687 0.5687
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0174 0.0585 0.1995
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0174 0.0585 0.0585
Schistosoma mansoni cell adhesion molecule 0.0099 0.0249 0.0249
Echinococcus granulosus serine threonine protein kinase nrc 0.0082 0.0176 0.0176
Trichomonas vaginalis CMGC family protein kinase 0.048 0.1954 0.3436
Echinococcus multilocularis FL cytokine receptor 0.0049 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Schistosoma mansoni vam6/vps39 related 0.0049 0.0028 0.0028
Leishmania major protein kinase, putative 0.0076 0.0149 0.0263
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0049 0.0028 0.0028
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Entamoeba histolytica cyclin, putative 0.1316 0.5687 1
Brugia malayi p70 ribosomal S6 kinase beta 0.0124 0.0363 0.0363
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0391 0.1553 0.1553
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0049 0.0028 0.0028
Schistosoma mansoni protein kinase 0.0049 0.0028 0.0028
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0095 0.0231 0.0231
Entamoeba histolytica serine/threonine kinase, putative 0.0049 0.0028 0.005
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0391 0.1553 0.1553
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.0585 0.1029
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0067 0.0108 0.0108
Trichomonas vaginalis cyclin B, putative 0.0174 0.0585 0.1029
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0049 0.0028 0.0028
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0262 0.098 0.1724
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0095 0.0231 0.0231
Echinococcus granulosus activin receptor type 0.0066 0.0102 0.0102
Brugia malayi Protein kinase domain containing protein 0.006 0.0074 0.0074
Schistosoma mansoni kinase 0.0064 0.0092 0.0092
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0049 0.0028 0.0028
Entamoeba histolytica PH domain containing protein kinase, putative 0.01 0.0255 0.0448
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0072 0.0129 0.0129
Echinococcus multilocularis dual specificity protein kinase clk2 0.0076 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0116 0.0327 0.0327
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0049 0.0028 0.005
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0095 0.0231 0.0231
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.032 0.1238 0.2176
Loa Loa (eye worm) hypothetical protein 0.0045 0.0008 0.0008
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.024 0.0879 0.0879
Echinococcus multilocularis protein KINase family member (kin 25) 0.0049 0.0028 0.0028
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0482 0.1963 0.1963
Entamoeba histolytica serine/threonine kinase, putative 0.0049 0.0028 0.005
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0058 0.0068 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.005
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0058 0.0068 0.0068
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0049 0.0028 0.005
Echinococcus granulosus cyclins 0.07 0.2934 0.2934
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0072 0.0129 0.0129
Brugia malayi Receptor family ligand binding region containing protein 0.0049 0.0028 0.0028
Echinococcus multilocularis tyrosine protein kinase csk 0.0049 0.0028 0.0028
Toxoplasma gondii cyclin dependent kinase binding protein 0.0174 0.0585 0.2714
Trichomonas vaginalis AGC family protein kinase 0.013 0.0387 0.068
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0482 0.1963 0.1963
Echinococcus granulosus Zinc finger DBF type 0.0104 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0174 0.0585 0.0585
Brugia malayi Immunoglobulin I-set domain containing protein 0.0448 0.1809 0.1809
Entamoeba histolytica protein kinase, putative 0.0067 0.0108 0.019
Echinococcus multilocularis Immunoglobulin 0.0082 0.0173 0.0173
Trichomonas vaginalis cyclin D, putative 0.07 0.2934 0.5159
Echinococcus multilocularis protein kinase c epsilon type 0.0067 0.0106 0.0106
Echinococcus granulosus NDR protein kinase 0.0058 0.0068 0.0068
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.005
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Loa Loa (eye worm) AGC/PKA protein kinase 0.0095 0.0231 0.0231
Toxoplasma gondii hypothetical protein 0.0526 0.2157 1
Echinococcus granulosus cyclin B3 1 0.07 0.2934 0.2934
Echinococcus multilocularis Zinc finger, DBF type 0.0477 0.1939 0.1939
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.005
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0082 0.0176 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0149 0.0149
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0231 0.0406
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus granulosus Glutaredoxin protein 5 0.0066 0.0103 0.0103
Trichomonas vaginalis AGC family protein kinase 0.013 0.0387 0.068
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0257 0.0956 0.0956
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0042 0.0074
Entamoeba histolytica SH2-protein kinase domain containing protein 0.006 0.0074 0.013
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.2282 1 1
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Trichomonas vaginalis AGC family protein kinase 0.013 0.0387 0.068
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Brugia malayi Protein kinase domain containing protein 0.006 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0167 0.0553 0.0553
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Loa Loa (eye worm) TK protein kinase 0.0049 0.0028 0.0028
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0124 0.0363 0.0363
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Echinococcus multilocularis protein kinase c iota type 0.0064 0.0095 0.0095
Loa Loa (eye worm) TK protein kinase 0.0049 0.0028 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Onchocerca volvulus 0.006 0.0074 0.0081
Echinococcus multilocularis cyclin t1 0.0174 0.0585 0.0585
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0049 0.0028 0.0028
Loa Loa (eye worm) TK/FER protein kinase 0.006 0.0074 0.0074
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0049 0.0028 0.0028
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0174 0.0585 0.0585
Echinococcus granulosus tyrosine protein kinase Fyn 0.0072 0.0129 0.0129
Giardia lamblia Hypothetical protein 0.0174 0.0585 0.0984
Loa Loa (eye worm) hypothetical protein 0.0093 0.0225 0.0225
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0101 0.0257 0.0452
Echinococcus multilocularis active breakpoint cluster region 0.01 0.0253 0.0253
Schistosoma mansoni vesicular amine transporter 0.0082 0.0173 0.0173
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0072 0.0128 0.0128
Brugia malayi Tyrosine-protein kinase PR2 0.0049 0.0028 0.0028
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0134 0.0406 0.0406
Schistosoma mansoni ephrin receptor 0.0049 0.0028 0.0028
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Brugia malayi Furin-like cysteine rich region family protein 0.0449 0.1813 0.1813
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.0585 0.1029
Loa Loa (eye worm) TK/FER protein kinase 0.006 0.0074 0.0074
Brugia malayi integrin-linked kinase 0.0049 0.0028 0.0028
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0244 0.09 0.09
Schistosoma mansoni tyrosine kinase 0.0083 0.018 0.018
Echinococcus multilocularis heat shock protein 70 0.0049 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Echinococcus granulosus epidermal growth factor receptor 0.0316 0.1218 0.1218
Trichomonas vaginalis STE family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis cyclins, putative 0.1316 0.5687 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0028 0.005
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0066 0.0102 0.0179
Trichomonas vaginalis cyclin B, putative 0.07 0.2934 0.5159
Loa Loa (eye worm) hypothetical protein 0.0129 0.0384 0.0384
Echinococcus multilocularis epidermal growth factor receptor 0.0316 0.1218 0.1218
Echinococcus granulosus G1:S specific cyclin D1 0.0174 0.0585 0.0585
Trichomonas vaginalis AGC family protein kinase 0.013 0.0387 0.068
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0095 0.0231 0.0787
Echinococcus granulosus Protein kinase C brain isozyme 0.0105 0.0279 0.0279
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0055 0.0055
Trichomonas vaginalis AGC family protein kinase 0.0058 0.0068 0.012
Echinococcus granulosus retinal guanylyl cyclase 2 0.0049 0.0028 0.0028
Echinococcus multilocularis tyrosine protein kinase 0.0049 0.0028 0.0028
Trypanosoma brucei mitotic cyclin 6 0.1316 0.5687 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0072 0.0129 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0108 0.0108
Echinococcus granulosus cyclins 0.07 0.2934 0.2934
Loa Loa (eye worm) TK/FER protein kinase 0.006 0.0074 0.0074
Entamoeba histolytica cyclin C, putative 0.0174 0.0585 0.1029
Trichomonas vaginalis CAMK family protein kinase 0.0244 0.09 0.1582
Schistosoma mansoni tyrosine kinase 0.0449 0.1813 0.1813
Trichomonas vaginalis cyclin A, putative 0.1316 0.5687 1
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0095 0.0231 0.1071
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Brugia malayi probable protein kinase 0.0183 0.0626 0.0626
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0068 0.0068
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0083 0.0083
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Trypanosoma cruzi cdc2-related kinase 3 0.048 0.1954 0.3436
Schistosoma mansoni protein kinase 0.0049 0.0028 0.0028
Schistosoma mansoni nephrin 0.0099 0.025 0.025
Echinococcus multilocularis tyrosine protein kinase csk 0.0049 0.0028 0.0028
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0262 0.098 0.098
Echinococcus multilocularis cyclin y 0.0174 0.0585 0.0585
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0049 0.0028 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0244 0.09 0.1582
Echinococcus multilocularis cyclins 0.07 0.2934 0.2934
Trypanosoma cruzi cdc2-related kinase 3 0.048 0.1954 0.3436
Onchocerca volvulus 0.006 0.0074 0.0081
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0159 0.0519 0.0867
Echinococcus granulosus activated cdc42 kinase 1 0.0049 0.0028 0.0028
Echinococcus granulosus tyrosine kinase 0.006 0.0074 0.0074
Onchocerca volvulus Cyclin L homolog 0.0174 0.0585 0.0984
Loa Loa (eye worm) hypothetical protein 0.02 0.0701 0.0701
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.005
Loa Loa (eye worm) TK/INSR protein kinase 0.0391 0.1553 0.1553
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus granulosus protein tyrosine kinase 0.0049 0.0028 0.0028
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0049 0.0028 0.0028
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.011 0.0301 0.0529
Echinococcus multilocularis serine:threonine protein kinase 38 0.0058 0.0068 0.0068
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.02 0.0702 0.0702
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Brugia malayi Protein kinase domain containing protein 0.0391 0.1553 0.1553
Brugia malayi Protein kinase domain containing protein 0.0829 0.351 0.351
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0116 0.0326 0.0326
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.006 0.0074 0.0074
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.005
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus multilocularis serine threonine protein kinase 0.01 0.0253 0.0253
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0058 0.0068 0.0068
Loa Loa (eye worm) cyclin C 0.0174 0.0585 0.0585
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0049 0.0028 0.005
Echinococcus multilocularis cyclins 0.07 0.2934 0.2934
Loa Loa (eye worm) AGC/NDR protein kinase 0.0058 0.0068 0.0068
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0049 0.0028 0.005
Echinococcus multilocularis epidermal growth factor receptor 0.0449 0.1813 0.1813
Leishmania major mitotic cyclin, putative 0.0174 0.0585 0.1029
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0049 0.0028 0.0028
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.024 0.0879 0.0879
Onchocerca volvulus 0.0127 0.0377 0.0617
Schistosoma mansoni protein kinase 0.0134 0.0406 0.0406
Loa Loa (eye worm) hypothetical protein 0.0082 0.0173 0.0173
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0377 0.0377
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.006 0.0074 0.0074
Trypanosoma cruzi cyclin, putative 0.1316 0.5687 1
Entamoeba histolytica protein kinase domain containing protein 0.011 0.0299 0.0525
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0066 0.0103 0.0103
Schistosoma mansoni tyrosine kinase 0.0266 0.0997 0.0997
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Onchocerca volvulus 0.0156 0.0505 0.0842
Brugia malayi hypothetical protein 0.0174 0.0585 0.0585
Trypanosoma cruzi mitotic cyclin, putative 0.0174 0.0585 0.1029
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase, putative 0.0156 0.0505 0.0888
Loa Loa (eye worm) TK/FER protein kinase 0.006 0.0074 0.0074
Schistosoma mansoni hypothetical protein 0.0049 0.0028 0.0028
Brugia malayi SH2 domain containing protein 0.006 0.0074 0.0074
Echinococcus multilocularis cyclin B 0.1316 0.5687 0.5687
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.011 0.0301 0.0529
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0072 0.0129 0.0129
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0064 0.0092 0.0092
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0072 0.0129 0.0129
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0095 0.0231 0.0406
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0066 0.0102 0.0102
Trichomonas vaginalis cyclin A, putative 0.0174 0.0585 0.1029
Trichomonas vaginalis AGC family protein kinase 0.013 0.0387 0.068
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0482 0.1963 0.1963
Loa Loa (eye worm) hypothetical protein 0.0082 0.0173 0.0173
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0634 0.2638 0.2638
Echinococcus multilocularis protein tyrosine kinase 0.0049 0.0028 0.0028
Plasmodium falciparum tyrosine kinase-like protein 0.0049 0.0028 0.0097
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Brugia malayi Cyclin, N-terminal domain containing protein 0.0174 0.0585 0.0585
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Trypanosoma cruzi polo-like protein kinase, putative 0.0244 0.09 0.1582
Echinococcus multilocularis CDC7 cell division cycle 7 0.0127 0.0377 0.0377
Entamoeba histolytica cysteine surface protein, putative 0.0049 0.0028 0.005
Loa Loa (eye worm) TK protein kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0377 0.0664
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0174 0.0585 0.0585
Leishmania major protein kinase, putative 0.0076 0.0149 0.0263
Echinococcus granulosus cyclins 0.0174 0.0585 0.0585
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Loa Loa (eye worm) TK/ABL protein kinase 0.0262 0.098 0.098
Echinococcus multilocularis tyrosine protein kinase csk 0.0049 0.0028 0.0028
Echinococcus granulosus cyclin dependent kinase 9 0.0072 0.0129 0.0129
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0095 0.0231 0.0231
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0049 0.0028 0.0028
Schistosoma mansoni cyclins 0.07 0.2934 0.2934
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0076 0.0149 0.0263
Brugia malayi Cyclin, N-terminal domain containing protein 0.0174 0.0585 0.0585
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0049 0.0028 0.0028
Echinococcus granulosus serine/threonine protein kinase 0.0088 0.02 0.02
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0082 0.0176 0.031
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.005
Loa Loa (eye worm) hypothetical protein 0.0464 0.1881 0.1881
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.0585 0.1029
Echinococcus granulosus c src tyrosine kinase 0.0072 0.0129 0.0129
Brugia malayi Protein kinase domain containing protein 0.0277 0.1044 0.1044
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.033 0.1281 0.2253
Brugia malayi hypothetical protein 0.0049 0.0028 0.0028
Echinococcus granulosus cyclin k 0.0174 0.0585 0.0585
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.011 0.0299 0.0525
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0174 0.0585 0.2995
Echinococcus granulosus tyrosine protein kinase Fps85D 0.006 0.0074 0.0074
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase, putative 0.0058 0.0068 0.012
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Leishmania major cyclin 9, putative 0.0174 0.0585 0.1029
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Schistosoma mansoni cyclin B3 0.2282 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0505 0.0888
Schistosoma mansoni protein kinase 0.0066 0.0102 0.0102
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Trypanosoma cruzi mitotic cyclin, putative 0.0174 0.0585 0.1029
Loa Loa (eye worm) hypothetical protein 0.1316 0.5687 0.5687
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0049 0.0028 0.0028
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0066 0.0103 0.0103
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0058 0.0066 0.0066
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0082 0.0173 0.0173
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.033 0.1281 0.2253
Loa Loa (eye worm) TK/FER protein kinase 0.006 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Echinococcus granulosus tm gpcr rhodopsin 0.0634 0.2638 0.2638
Brugia malayi Protein kinase domain containing protein 0.0482 0.1963 0.1963
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.048 0.1954 0.1954
Entamoeba histolytica cyclin, putative 0.07 0.2934 0.5159
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0068 0.0068
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Echinococcus granulosus cyclin y 0.0174 0.0585 0.0585
Echinococcus granulosus raf serine:threonine protein kinase 0.0055 0.0055 0.0055
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Brugia malayi ephrin receptor 1 precursor 0.0049 0.0028 0.0028
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0072 0.0129 0.0129
Trichomonas vaginalis AGC family protein kinase 0.013 0.0387 0.068
Echinococcus granulosus cyclin 0.0174 0.0585 0.0585
Giardia lamblia Hypothetical protein 0.0174 0.0585 0.0984
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus multilocularis 0.0134 0.0406 0.0406
Loa Loa (eye worm) cyclin domain-containing protein 0.0174 0.0585 0.0585
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0511 0.2092 0.2092
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.011 0.0299 0.0525
Schistosoma mansoni protein kinase 0.0049 0.0028 0.0028
Brugia malayi protein kinase C II. 0.0067 0.0106 0.0106
Echinococcus granulosus tyrosine protein kinase Lyn 0.0088 0.0202 0.0202
Schistosoma mansoni cyclin B 0.1316 0.5687 0.5687
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0829 0.351 0.351
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.048 0.1954 0.1954
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus granulosus Cyclin L1 0.0174 0.0585 0.0585
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.005
Loa Loa (eye worm) hypothetical protein 0.0058 0.0068 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0282 0.0496
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0174 0.0585 0.1029
Schistosoma mansoni tyrosine kinase 0.0391 0.1553 0.1553
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0058 0.0068 0.0068
Onchocerca volvulus Tyrosine kinase homolog 0.0366 0.1445 0.2503
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.0174 0.0585 0.1029
Schistosoma mansoni serine/threonine protein kinase 0.048 0.1954 0.1954
Schistosoma mansoni tyrosine kinase 0.0266 0.0997 0.0997
Brugia malayi SRC-1 0.0072 0.0129 0.0129
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0066 0.0105 0.0105
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0049 0.0028 0.0028
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0269 0.1011 0.1011
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0076 0.0149 0.0263
Echinococcus multilocularis Immunoglobulin 0.0082 0.0173 0.0173
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0095 0.0231 0.0406
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.005
Echinococcus multilocularis raf serine:threonine protein kinase 0.0055 0.0055 0.0055
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Echinococcus granulosus cyclin t1 0.0174 0.0585 0.0585
Echinococcus granulosus cyclin G2 0.0174 0.0585 0.0585
Echinococcus multilocularis cyclin G2 0.0174 0.0585 0.0585
Echinococcus multilocularis tyrosine protein kinase shark 0.006 0.0074 0.0074
Echinococcus granulosus CDC7 cell division cycle 7 0.0127 0.0377 0.0377
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0231 0.0231
Echinococcus multilocularis tyrosine protein kinase pr2 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Loa Loa (eye worm) TK/DDR protein kinase 0.0049 0.0028 0.0028
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.005
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.005
Schistosoma mansoni protein kinase 0.0049 0.0028 0.0028
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Loa Loa (eye worm) TK protein kinase 0.006 0.0074 0.0074
Trypanosoma brucei Flagellum attachment zone protein 20 0.0049 0.0028 0.005
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0095 0.0231 0.0231
Echinococcus granulosus natriuretic peptide receptor 1 0.0049 0.0028 0.0028
Loa Loa (eye worm) TK protein kinase 0.0049 0.0028 0.0028
Brugia malayi Temporarily assigned gene name protein 59 0.0049 0.0028 0.0028
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0348 0.1363 0.1363
Echinococcus multilocularis insulin receptor 0.0391 0.1553 0.1553
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0095 0.0231 0.0231
Onchocerca volvulus 0.03 0.1148 0.1979
Schistosoma mansoni kinase 0.0262 0.0979 0.0979
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Trichomonas vaginalis protein tyrosine kinase, putative 0.0049 0.0028 0.005
Schistosoma mansoni tyrosine kinase 0.0072 0.0129 0.0129
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0082 0.0176 0.0902
Entamoeba histolytica protein kinase, putative 0.011 0.0299 0.0525
Loa Loa (eye worm) CDC7 protein kinase 0.0127 0.0377 0.0377
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Entamoeba histolytica PH domain containing protein kinase, putative 0.01 0.0255 0.0448
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0227 0.082 0.1442
Echinococcus granulosus cyclin y 0.0174 0.0585 0.0585
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.011 0.0299 0.0299
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Brugia malayi hypothetical protein 0.0129 0.0384 0.0384
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0156 0.0505 0.0505
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Leishmania major protein kinase A catalytic subunit isoform 1 0.0095 0.0231 0.0406
Trypanosoma cruzi cdc2-related kinase 1 0.048 0.1954 0.3436
Plasmodium vivax hypothetical protein, conserved 0.0174 0.0585 0.2995
Schistosoma mansoni tyrosine kinase 0.0391 0.1553 0.1553
Echinococcus granulosus cyclins 0.07 0.2934 0.2934
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0067 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.0477 0.1939 0.1939
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0138 0.0424 0.0424
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Echinococcus granulosus protein kinase 0.0049 0.0028 0.0028
Echinococcus granulosus tyrosine protein kinase 0.0049 0.0028 0.0028
Loa Loa (eye worm) cyclin domain-containing protein 0.2282 1 1
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0273 0.0481
Echinococcus granulosus receptor type guanylyl cyclase 0.0049 0.0028 0.0028
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0049 0.0028 0.0028
Plasmodium vivax tyrosine kinase-like protein, putative 0.0049 0.0028 0.0145
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus multilocularis Cyclin L1 0.0174 0.0585 0.0585
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.048 0.1954 0.1954
Echinococcus granulosus twitchin 0.0115 0.0323 0.0323
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Schistosoma mansoni tyrosine protein kinase 0.0049 0.0028 0.0028
Entamoeba histolytica serine/threonine kinase, putative 0.0049 0.0028 0.005
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0095 0.0231 0.0406
Brugia malayi protein-tyrosine kinase 0.006 0.0074 0.0074
Echinococcus multilocularis tyrosine kinase 0.006 0.0074 0.0074
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0049 0.0028 0.0028
Brugia malayi Cyclin, N-terminal domain containing protein 0.0174 0.0585 0.0585
Echinococcus granulosus cyclin dependent kinase 9 0.0064 0.0092 0.0092
Loa Loa (eye worm) TK/Met protein kinase 0.0049 0.0028 0.0028
Echinococcus granulosus fibroblast growth factor receptor 4 0.024 0.0879 0.0879
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.033 0.1281 0.2253
Brugia malayi Immunoglobulin I-set domain containing protein 0.0082 0.0173 0.0173
Onchocerca volvulus 0.006 0.0074 0.0081
Entamoeba histolytica protein kinase 2, putative 0.0082 0.0176 0.031
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0066 0.0102 0.0102
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0049 0.0028 0.005
Schistosoma mansoni protein kinase 0.0066 0.0102 0.0102
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus granulosus tyrosine protein kinase ABL1 0.0262 0.098 0.098
Plasmodium vivax protein kinase Crk2 0.048 0.1954 1
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0156 0.0505 0.0505
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0082 0.0176 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0128 0.0128
Entamoeba histolytica cyclin family protein 0.07 0.2934 0.5159
Trichomonas vaginalis CAMK family protein kinase 0.0244 0.09 0.1582
Plasmodium vivax protein kinase, putative 0.0049 0.0028 0.0145
Entamoeba histolytica PH domain containing protein kinase, putative 0.0088 0.02 0.0351
Plasmodium vivax tyrosine kinase-like protein, putative 0.0049 0.0028 0.0145
Loa Loa (eye worm) TK/ALK protein kinase 0.0277 0.1043 0.1043
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0448 0.1809 0.1809
Echinococcus multilocularis tyrosine protein kinase Srms 0.006 0.0074 0.0074
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Brugia malayi phosphoinositide-dependent protein kinase I 0.0067 0.0108 0.0108
Brugia malayi Protein kinase domain containing protein 0.0127 0.0377 0.0377
Echinococcus granulosus cyclin dependent kinase 5 0.048 0.1954 0.1954
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0049 0.0028 0.0131
Echinococcus granulosus protein kinase C gamma type 0.01 0.0253 0.0253
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Schistosoma mansoni serine/threonine-protein kinase 0.0088 0.02 0.02
Leishmania major protein kinase A catalytic subunit isoform 2 0.0095 0.0231 0.0406
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0146 0.0461 0.0811
Echinococcus multilocularis G1:S specific cyclin D1 0.0174 0.0585 0.0585
Echinococcus granulosus defective proboscis extension response 0.0082 0.0173 0.0173
Entamoeba histolytica PH domain containing protein kinase, putative 0.0088 0.02 0.0351
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Echinococcus granulosus serine:threonine protein kinase N2 0.0058 0.0068 0.0068
Giardia lamblia Kinase, CMGC GSK 0.0156 0.0505 0.0842
Brugia malayi Protein kinase domain containing protein 0.0066 0.0102 0.0102
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0067 0.0108 0.0108
Toxoplasma gondii protein kinase 0.0049 0.0028 0.0131
Entamoeba histolytica hypothetical protein, conserved 0.0049 0.0028 0.005
Schistosoma mansoni serine/threonine-protein kinase 0.0088 0.02 0.02
Schistosoma mansoni tyrosine kinase 0.0072 0.0129 0.0129
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0244 0.09 0.1582
Brugia malayi Cyclin C 0.0174 0.0585 0.0585
Echinococcus granulosus tyrosine protein kinase csk 0.0049 0.0028 0.0028
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Schistosoma mansoni serine/threonine kinase 0.0058 0.0068 0.0068
Brugia malayi Protein kinase domain containing protein 0.013 0.0387 0.0387
Trichomonas vaginalis cyclin B, putative 0.1316 0.5687 1
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0072 0.0128 0.0128
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0072 0.0129 0.0129
Echinococcus granulosus nervana 2 0.0066 0.0103 0.0103
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus granulosus tyrosine protein kinase Srms 0.006 0.0074 0.0074
Echinococcus multilocularis fibroblast growth factor receptor 4 0.024 0.0879 0.0879
Schistosoma mansoni protein kinase 0.0066 0.0102 0.0102
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0348 0.1363 0.1363
Trichomonas vaginalis cyclin B, putative 0.0174 0.0585 0.1029
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Loa Loa (eye worm) RGC/RGC protein kinase 0.0049 0.0028 0.0028
Echinococcus multilocularis cyclin dependent kinase 9 0.0072 0.0129 0.0129
Echinococcus multilocularis cyclin b3 0.07 0.2934 0.2934
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0128 0.0128
Brugia malayi Cyclin, N-terminal domain containing protein 0.0174 0.0585 0.0585
Schistosoma mansoni cyclin G2 0.0174 0.0585 0.0585
Trichomonas vaginalis cyclin B, putative 0.1316 0.5687 1
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0076 0.0149 0.0263
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0049 0.0028 0.0131
Brugia malayi Protein kinase domain containing protein 0.006 0.0074 0.0074
Trypanosoma cruzi polo-like protein kinase, putative 0.0244 0.09 0.1582
Loa Loa (eye worm) TK/ROR protein kinase 0.0066 0.0105 0.0105
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus multilocularis protein kinase 0.0049 0.0028 0.0028
Echinococcus granulosus protein kinase c epsilon type 0.0067 0.0106 0.0106
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0072 0.0129 0.0129
Brugia malayi Tyrosine-protein kinase abl-1 0.0149 0.0476 0.0476
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis CMGC family protein kinase 0.048 0.1954 0.3436
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0095 0.0231 0.0406
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0095 0.0231 0.0406
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.005
Echinococcus multilocularis cyclin G2 0.0174 0.0585 0.0585
Loa Loa (eye worm) hypothetical protein 0.006 0.0074 0.0074
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0049 0.0028 0.005
Schistosoma mansoni protein kinase 0.0183 0.0626 0.0626
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0273 0.0481
Trichomonas vaginalis CAMK family protein kinase 0.0244 0.09 0.1582
Plasmodium falciparum protein kinase 5 0.048 0.1954 0.6661
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Entamoeba histolytica hypothetical protein 0.0262 0.098 0.1724
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0072 0.0129 0.0129
Echinococcus granulosus tyrosine kinase 0.006 0.0074 0.0074
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0511 0.2092 0.2092
Brugia malayi Protein kinase domain containing protein 0.006 0.0074 0.0074
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0156 0.0505 0.0888
Loa Loa (eye worm) cyclin domain-containing protein 0.0174 0.0585 0.0585
Toxoplasma gondii cyclin 4, putative 0.0174 0.0585 0.2714
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0058 0.0068 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.1363 0.1363
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0078 0.0158 0.0158
Echinococcus multilocularis nervana 2 0.0066 0.0103 0.0103
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0076 0.0149 0.0692
Echinococcus multilocularis kinase suppressor of Ras 1 0.0049 0.0028 0.0028
Brugia malayi hypothetical protein 0.0049 0.0028 0.0028
Loa Loa (eye worm) TK/RYK protein kinase 0.0049 0.0028 0.0028
Echinococcus granulosus tyrosine protein kinase Blk 0.006 0.0074 0.0074
Trypanosoma brucei cdc2-related kinase 1 0.048 0.1954 0.3436
Plasmodium falciparum cyclin 0.07 0.2934 1
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis cyclin B3, putative 0.0174 0.0585 0.1029
Trypanosoma cruzi cyclin, putative 0.1316 0.5687 1
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0099 0.0249 0.0249
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0076 0.0149 0.0263
Entamoeba histolytica hypothetical protein 0.011 0.0299 0.0525
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.048 0.1954 0.3436
Loa Loa (eye worm) TK protein kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0253 0.0937 0.1647
Echinococcus multilocularis cyclins 0.07 0.2934 0.2934
Schistosoma mansoni serine/threonine protein kinase 0.048 0.1954 0.1954
Giardia lamblia Hypothetical protein 0.07 0.2934 0.5134
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0182 0.0619 0.0619
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0269 0.1011 0.1011
Plasmodium falciparum protein serine/threonine kinase-1 0.0076 0.0149 0.0509
Echinococcus multilocularis cyclins 0.07 0.2934 0.2934
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0601 0.0601
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0082 0.0173 0.0173
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.033 0.1281 0.2253
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0282 0.0496
Loa Loa (eye worm) serine/threonine protein kinase 0.0049 0.0028 0.0028
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0082 0.0176 0.0601
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0124 0.0361 0.0361
Entamoeba histolytica serine/threonine kinase, putative 0.0049 0.0028 0.005
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Echinococcus granulosus tyrosine protein kinase HCK 0.0049 0.0028 0.0028
Entamoeba histolytica serine/threonine kinase, putative 0.0049 0.0028 0.005
Onchocerca volvulus 0.006 0.0074 0.0081
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Entamoeba histolytica serine/threonine protein kinase, putative 0.0244 0.09 0.1582
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Schistosoma mansoni protein kinase 0.0049 0.0028 0.0028
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.048 0.1954 0.3436
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0066 0.0102 0.0471
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0482 0.1963 0.1963
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Echinococcus multilocularis roundabout 2 0.0116 0.0326 0.0326
Trypanosoma brucei cdc2-related kinase 3 0.048 0.1954 0.3436
Echinococcus multilocularis cyclins 0.07 0.2934 0.2934
Echinococcus multilocularis cyclin y 0.0174 0.0585 0.0585
Schistosoma mansoni tyrosine kinase 0.0188 0.0646 0.0646
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0279 0.0279
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Trichomonas vaginalis protein kinase atn1, putative 0.0049 0.0028 0.005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0066 0.0102 0.0102
Brugia malayi Protein kinase domain containing protein 0.0178 0.0601 0.0601
Giardia lamblia Cyclin B-like protein 0.0174 0.0585 0.0984
Loa Loa (eye worm) TK/ACK protein kinase 0.0049 0.0028 0.0028
Echinococcus multilocularis protein kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0049 0.0028 0.005
Echinococcus granulosus nervana 2 0.0066 0.0103 0.0103
Trichomonas vaginalis cyclin D, putative 0.07 0.2934 0.5159
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0214 0.0762 0.0762
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.048 0.1954 0.9061
Giardia lamblia Kinase, AGC PKA 0.0095 0.0231 0.0358
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Onchocerca volvulus 0.1316 0.5687 1
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Giardia lamblia Kinase, PLK 0.0244 0.09 0.154
Echinococcus multilocularis cyclin k 0.0174 0.0585 0.0585
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0149 0.0263
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Echinococcus multilocularis 0.006 0.0076 0.0076
Schistosoma mansoni g1/s-specific cyclin C 0.0174 0.0585 0.0585
Giardia lamblia Kinase, CMGC CDK 0.048 0.1954 0.3403
Brugia malayi Cyclin, N-terminal domain containing protein 0.0174 0.0585 0.0585
Echinococcus granulosus kinase suppressor of Ras 1 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trypanosoma brucei cyclin 9 0.0174 0.0585 0.1029
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Loa Loa (eye worm) AGC/AKT protein kinase 0.013 0.0387 0.0387
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Loa Loa (eye worm) hypothetical protein 0.0214 0.0762 0.0762
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.011 0.0299 0.0525
Trypanosoma cruzi protein kinase, putative 0.0049 0.0028 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0244 0.09 0.1582
Trichomonas vaginalis cyclin B3, putative 0.0174 0.0585 0.1029
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0505 0.0888
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0082 0.0173 0.0173
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Brugia malayi Protein kinase domain containing protein 0.0076 0.0149 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.005
Giardia lamblia Kinase, CMGC GSK 0.0156 0.0505 0.0842
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0299 0.0299
Giardia lamblia Kinase, CMGC CDK 0.048 0.1954 0.3403
Schistosoma mansoni hypothetical protein 0.0174 0.0585 0.0585
Plasmodium vivax serine/threonine kinase-1, putative 0.0076 0.0149 0.0764
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Giardia lamblia Kinase, CMGC CLK 0.0076 0.0149 0.0214
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0028
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0227 0.082 0.1442
Entamoeba histolytica receptor protein kinase, putative 0.0049 0.0028 0.005
Loa Loa (eye worm) hypothetical protein 0.0082 0.0173 0.0173
Echinococcus granulosus tyrosine protein kinase pr2 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0279 0.0279
Echinococcus multilocularis dual specificity 0.011 0.0299 0.0299
Entamoeba histolytica cell division protein kinase 2, putative 0.0489 0.1991 0.3501
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0214 0.0762 0.0762
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0124 0.0361 0.0361
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.048 0.1954 0.1954
Brugia malayi intracellular kinase 0.0156 0.0505 0.0505
Echinococcus granulosus cyclins 0.07 0.2934 0.2934
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0348 0.1363 0.1363
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0216 0.0773 0.0773
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus multilocularis 0.0122 0.0354 0.0354
Loa Loa (eye worm) RGC/RGC protein kinase 0.0049 0.0028 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.09 0.09
Loa Loa (eye worm) TK/FER protein kinase 0.0049 0.0028 0.0028
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0049 0.0028 0.0028
Brugia malayi Cyclin, N-terminal domain containing protein 0.1316 0.5687 0.5687
Brugia malayi Guanylyl cyclase protein 23 0.0049 0.0028 0.0028
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0482 0.1963 0.3418
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Loa Loa (eye worm) TK/EGFR protein kinase 0.0449 0.1813 0.1813
Schistosoma mansoni serine/threonine RGC 0.0049 0.0028 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.005
Entamoeba histolytica tyrosin kinase, putative 0.0049 0.0028 0.005
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Entamoeba histolytica protein kinase, putative 0.0124 0.0363 0.0639
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0066 0.0102 0.0102
Leishmania major hypothetical protein, conserved 0.0049 0.0028 0.005
Echinococcus multilocularis tyrosine protein kinase Blk 0.006 0.0074 0.0074
Echinococcus multilocularis activated cdc42 kinase 1 0.0049 0.0028 0.0028
Entamoeba histolytica tyrosine kinase, putative 0.0049 0.0028 0.005
Trypanosoma cruzi cdc2-related kinase 1 0.048 0.1954 0.3436
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Loa Loa (eye worm) SRC-1 0.0072 0.0129 0.0129
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.011 0.0301 0.0529
Brugia malayi Protein kinase domain containing protein 0.0187 0.0644 0.0644
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.011 0.0301 0.0529
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0377 0.0664
Plasmodium falciparum protein kinase, putative 0.0049 0.0028 0.0097
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.011 0.0301 0.0301
Loa Loa (eye worm) cyclin domain-containing protein 0.0174 0.0585 0.0585
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.011 0.0299 0.0525
Brugia malayi Protein kinase domain containing protein 0.0058 0.0068 0.0068
Loa Loa (eye worm) protein kinase domain-containing protein 0.0049 0.0028 0.0028
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0049 0.0028 0.005
Schistosoma mansoni cyclin l 0.0174 0.0585 0.0585
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.1363 0.2396
Onchocerca volvulus Cyclin L homolog 0.0174 0.0585 0.0984
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0049 0.0028 0.0028
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0167 0.0553 0.0553
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0049 0.0028 0.0028
Echinococcus granulosus cyclin B 0.1316 0.5687 0.5687
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0174 0.0585 0.1995
Loa Loa (eye worm) phosphatidylinositol 3 0.0444 0.1791 0.1791
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis cyclins, putative 0.1316 0.5687 1
Leishmania major protein kinase A catalytic subunit 0.0095 0.0231 0.0406
Loa Loa (eye worm) hypothetical protein 0.0099 0.0249 0.0249
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0174 0.0585 0.0585
Loa Loa (eye worm) hypothetical protein 0.0269 0.1011 0.1011
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Trichomonas vaginalis AGC family protein kinase 0.0075 0.0145 0.0255
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0174 0.0585 0.0585
Echinococcus granulosus cyclin b3 0.07 0.2934 0.2934
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0072 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0093 0.0225 0.0225
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0231 0.0231
Giardia lamblia Kinase, AGC PKA 0.0082 0.0176 0.0261
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0049 0.0028 0.0028
Schistosoma mansoni protein kinase 0.0049 0.0028 0.0028
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0269 0.1011 0.1011
Echinococcus granulosus retinal guanylyl cyclase 2 0.0049 0.0028 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0049 0.0028 0.005
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0095 0.0231 0.0231
Plasmodium falciparum protein kinase, putative 0.0049 0.0028 0.0097
Loa Loa (eye worm) hypothetical protein 0.1316 0.5687 0.5687
Entamoeba histolytica protein kinase, putative 0.0049 0.0028 0.005
Entamoeba histolytica protein kinase, putative 0.011 0.0299 0.0525
Trichomonas vaginalis TKL family protein kinase 0.0049 0.0028 0.005
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0174 0.0585 0.2714
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0049 0.0028 0.0028
Brugia malayi cell division control protein 2 homolog 0.048 0.1954 0.1954
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0983 0.4197 0.4197
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0049 0.0028 0.005
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0511 0.2092 0.2092
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Schistosoma mansoni tyrosine kinase 0.0049 0.0028 0.0028
Toxoplasma gondii AGC kinase 0.0095 0.0231 0.1071
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.011 0.0301 0.0529
Brugia malayi hypothetical protein 0.006 0.0074 0.0074
Echinococcus granulosus Vam6:Vps39 protein 0.0049 0.0028 0.0028
Echinococcus multilocularis activin receptor type 0.0066 0.0102 0.0102
Brugia malayi Protein kinase domain containing protein 0.0049 0.0028 0.0028
Echinococcus granulosus tyrosine protein kinase csk 0.0049 0.0028 0.0028
Brugia malayi SH2 domain containing protein 0.006 0.0074 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.07 0.2934 0.5159
Schistosoma mansoni hypothetical protein 0.0174 0.0585 0.0585
Echinococcus granulosus protein kinase c iota type 0.0064 0.0095 0.0095
Echinococcus multilocularis rac serine:threonine kinase 0.0088 0.02 0.02
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.0028 0.005
Loa Loa (eye worm) AGC/PKA protein kinase 0.0095 0.0231 0.0231

Activities

Activity type Activity value Assay description Source Reference
Ke (functional) = 0.72 nM Activity at human recombinant delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assay ChEMBL. 15588100
Ke (functional) = 0.72 nM Activity at human recombinant delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assay ChEMBL. 15588100
Ke (functional) = 10.7 nM Activity at human recombinant mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assay ChEMBL. 15588100
Ke (functional) = 10.7 nM Activity at human recombinant mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assay ChEMBL. 15588100
Ke (functional) = 44 nM Activity at human recombinant kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assay ChEMBL. 15588100
Ke (functional) = 44 nM Activity at human recombinant kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assay ChEMBL. 15588100
Ki (binding) = 2.95 nM Displacement of [3H]Cl-DPDPE from human recombinant delta opioid receptor expressed in CHO cells ChEMBL. 15588100
Ki (binding) = 2.95 nM Displacement of [3H]Cl-DPDPE from human recombinant delta opioid receptor expressed in CHO cells ChEMBL. 15588100
Ki (binding) = 8.75 nM Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells ChEMBL. 15588100
Ki (binding) = 8.75 nM Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells ChEMBL. 15588100
Ki (binding) = 24.3 nM Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells ChEMBL. 15588100
Ki (binding) = 24.3 nM Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells ChEMBL. 15588100

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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