Detailed information for compound 557006

Basic information

Technical information
  • TDR Targets ID: 557006
  • Name: [(1S)-3-allyl-2-methyl-4-oxo-cyclopent-2-en-1 -yl] (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-e nyl)cyclopropanecarboxylate
  • MW: 302.408 | Formula: C19H26O3
  • H donors: 0 H acceptors: 2 LogP: 3.68 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCC1=C(C)[C@H](CC1=O)OC(=O)[C@@H]1[C@H](C1(C)C)C=C(C)C
  • InChi: 1S/C19H26O3/c1-7-8-13-12(4)16(10-15(13)20)22-18(21)17-14(9-11(2)3)19(17,5)6/h7,9,14,16-17H,1,8,10H2,2-6H3/t14-,16+,17+/m1/s1
  • InChiKey: ZCVAOQKBXKSDMS-PVAVHDDUSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylic acid [(1S)-3-allyl-2-methyl-4-oxo-1-cyclopent-2-enyl] ester
  • [(1S)-2-methyl-4-oxo-3-prop-2-enyl-cyclopent-2-en-1-yl] (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
  • (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylic acid [(1S)-3-allyl-4-keto-2-methyl-cyclopent-2-en-1-yl] ester
  • [(1S)-2-methyl-4-oxo-3-prop-2-enylcyclopent-2-en-1-yl] (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
  • bioallethrin
  • esbiothrin
  • [(1S)-2-methyl-4-oxo-3-prop-2-enyl-1-cyclopent-2-enyl] (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
  • [(1S)-3-allyl-2-methyl-4-oxo-1-cyclopent-2-enyl] (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
  • (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)-1-cyclopropanecarboxylic acid [(1S)-3-allyl-2-methyl-4-oxo-1-cyclopent-2-enyl] ester
  • (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylic acid [(1S)-3-allyl-4-keto-2-methyl-1-cyclopent-2-enyl] ester
  • (1S)-3-allyl-2-methyl-4-oxocyclopent-2-en-1-yl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate
  • CHEBI:39115
  • bioallethrin S-cyclopentenyl
  • bioallethrin S-cyclopentenyl isomer
  • 2-Methyl-4-oxo-3-(2-propenyl)-2-cyclopenten-1-yl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate trans-(+)-
  • Caswell No. 025A
  • Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, 2-methyl-4-oxo-3-(2-propenyl)-2-cyclopenten-1-yl ester, trans-(+)-
  • D-TRANS-ALLETHRIN
  • DL-2-Allyl-4-hydroxy-3-methyl-2-cyclopenten-1-one, d-trans-chrysanthemum monocarboxylic ester
  • d-trans-Chrysanthemic acid of d-allethrone
  • (1S)-2-methyl-4-oxo-3-prop-2-en-1-ylcyclopent-2-en-1-yl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate
  • 45470_RIEDEL
  • 3-Allyl-2-methyl-4-oxo-2-cyclopentenyl chrysanthemate
  • 33309_RIEDEL
  • (1S)-2-methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate
  • (+)-trans-(S)-allethrin
  • PS790_SUPELCO

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni alpha-glucosidase 0.0137 0.0207 0.025
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0136 0.0206 1
Brugia malayi hypothetical protein 0.0038 0.0012 0.0029
Loa Loa (eye worm) patched family protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Loa Loa (eye worm) TAR-binding protein 0.007 0.0076 0.0086
Brugia malayi photoreceptor-specific nuclear receptor 0.0085 0.0106 0.061
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0037 0.001 0.0399
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0066 0.036
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0015 0.0408
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0085 0.0106 0.0123
Toxoplasma gondii HEAT repeat-containing protein 0.0061 0.0057 0.2521
Onchocerca volvulus 0.004 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Toxoplasma gondii patched family protein 0.0038 0.0012 0.0233
Echinococcus granulosus snurportin 1 0.0647 0.1214 0.1502
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.008 0.3651
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.0011 0.0207
Loa Loa (eye worm) hypothetical protein 0.0072 0.008 0.009
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0085 0.0106 0.061
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.008 0.0943
Loa Loa (eye worm) patched family protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.008 0.0391
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.001 0.0151
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0066 0.036
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0085 0.0106 0.0125
Schistosoma mansoni hypothetical protein 0.0065 0.0066 0.0074
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0136 0.0206 0.1226
Entamoeba histolytica acyl-CoA synthetase, putative 0.0125 0.0184 0.1539
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0085 0.0106 0.01
Echinococcus granulosus thyroid hormone receptor alpha 0.004 0.0017 0.0014
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0629 0.1178 0.1457
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0066 0.006
Giardia lamblia Replication factor C, subunit 1 0.0052 0.0039 0.1264
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.001 0.0151
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.0011 0.0207
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0136 0.0206 0.1072
Loa Loa (eye worm) hepatopoietin HPO2 0.0037 0.0011 0.0005
Leishmania major hypothetical protein, conserved 0.0136 0.0206 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Schistosoma mansoni RAR-like nuclear receptor 0.0085 0.0106 0.0125
Echinococcus multilocularis Nuclear hormone receptor HR96 0.004 0.0017 0.0011
Schistosoma mansoni tar DNA-binding protein 0.007 0.0076 0.0088
Loa Loa (eye worm) hypothetical protein 0.0093 0.0122 0.0143
Mycobacterium ulcerans ion transport protein 0.0136 0.0206 0.1245
Echinococcus multilocularis ecdysone induced protein 78C 0.0085 0.0106 0.01
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0017 0.0011
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0136 0.0206 0.1226
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0093 0.0122 0.1443
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0066 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0085 0.0106 0.061
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0066 0.0074
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0037 0.001 0.0004
Mycobacterium ulcerans hypothetical protein 0.0125 0.0184 0.1108
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0136 0.0206 0.1072
Onchocerca volvulus 0.0136 0.0206 0.1057
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0136 0.0206 0.1226
Trypanosoma cruzi hypothetical protein, conserved 0.0052 0.0039 0.162
Loa Loa (eye worm) hypothetical protein 0.0077 0.009 0.0103
Echinococcus multilocularis importin subunit beta 1 0.0061 0.0057 0.0051
Mycobacterium ulcerans acyl-CoA synthetase 0.0125 0.0184 0.1108
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0066 0.0074
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0017 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.008 0.3651
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0052 0.0039 0.162
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0028 0.0028
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0037 0.001 0.0399
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.008 0.0943
Brugia malayi nuclear receptor NHR-88 0.004 0.0017 0.0061
Onchocerca volvulus Protein patched homolog 0.0038 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0037 0.001 0.0151
Brugia malayi beta-lactamase family protein 0.0072 0.008 0.0448
Mycobacterium tuberculosis Conserved protein 0.0072 0.008 0.0943
Onchocerca volvulus 0.0085 0.0106 0.0518
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.0251 0.0303
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.004
Loa Loa (eye worm) hypothetical protein 0.0125 0.0184 0.022
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0085 0.0106 0.0518
Onchocerca volvulus Protein ultraspiracle homolog 0.0085 0.0106 0.0518
Brugia malayi AMP-binding enzyme family protein 0.0125 0.0184 0.1093
Brugia malayi nuclear receptor NHR-67 0.004 0.0017 0.0061
Echinococcus granulosus nibrin 0.0052 0.0039 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0085 0.0106 0.061
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0266 0.0462 0.0565
Loa Loa (eye worm) hypothetical protein 0.0168 0.0269 0.0325
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.0011 0.0207
Brugia malayi hypothetical protein 0.0038 0.0012 0.0029
Entamoeba histolytica hypothetical protein 0.0052 0.0039 0.028
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0112 0.1324
Echinococcus multilocularis protein patched 0.0266 0.0462 0.0456
Echinococcus multilocularis Niemann Pick C1 protein 0.0619 0.1159 0.1154
Brugia malayi beta-lactamase 0.0072 0.008 0.0448
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Echinococcus granulosus expressed conserved protein 0.0582 0.1085 0.1342
Brugia malayi nuclear hormone receptor family member odr-7 0.004 0.0017 0.0061
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0136 0.0206 0.02
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Leishmania major 4-coumarate:coa ligase-like protein 0.0125 0.0184 0.8914
Onchocerca volvulus 0.0136 0.0206 0.1057
Entamoeba histolytica hypothetical protein 0.0228 0.0387 0.3294
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Mycobacterium ulcerans hypothetical protein 0.0072 0.008 0.0442
Onchocerca volvulus 0.0038 0.0012 0.0009
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.0113 0.0107
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0093 0.0122 0.0711
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.001 0.0151
Echinococcus granulosus calcium activated potassium channel variant 0.0136 0.0206 0.0249
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Plasmodium falciparum importin beta, putative 0.0061 0.0057 0.2407
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0085 0.0106 0.061
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0379 0.0685 0.0844
Schistosoma mansoni DNA ligase IV 0.0052 0.0039 0.0042
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0045 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0093 0.0122 1
Trichomonas vaginalis conserved hypothetical protein 0.0266 0.0462 0.2451
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0052 0.0039 1
Brugia malayi Patched related family protein 4 0.0038 0.0012 0.0029
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.008 0.0092
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.001 0.0119
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0112 0.1324
Loa Loa (eye worm) hypothetical protein 0.0125 0.0184 0.022
Brugia malayi glutaminase DH11.1 0.0834 0.1584 0.972
Loa Loa (eye worm) hypothetical protein 0.0037 0.001 0.0004
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0037 0.0011 0.0005
Onchocerca volvulus 0.0052 0.0039 0.0158
Entamoeba histolytica hypothetical protein 0.0228 0.0387 0.3294
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0136 0.0206 0.0249
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0052 0.0039 0.0186
Brugia malayi nuclear hormone receptor family member nhr-6 0.004 0.0017 0.0061
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0037 0.001 0.0119
Onchocerca volvulus 0.0168 0.0269 0.1396
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0123 0.018 0.0175
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Trypanosoma cruzi importin beta-1 subunit, putative 0.0049 0.0035 0.1384
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0037 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0037 0.0011 0.0007
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0136 0.0206 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0171 0.0206
Trypanosoma brucei PAB1-binding protein , putative 0.0077 0.009 0.4149
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0085 0.0106 0.061
Brugia malayi beta-lactamase family protein 0.0072 0.008 0.0448
Schistosoma mansoni thyroid hormone receptor 0.0464 0.0853 0.1053
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.009 0.406
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.0011 0.0207
Schistosoma mansoni ap endonuclease 0.0039 0.0015 0.0012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0085 0.0106 0.0125
Schistosoma mansoni nuclear receptor 0.004 0.0017 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.018 0.0217
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0857 0.1629 0.2016
Echinococcus granulosus Nuclear hormone receptor HR96 0.004 0.0017 0.0014
Brugia malayi hypothetical protein 0.0045 0.0027 0.012
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.004 0.0017 0.0061
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0015 0.0044
Plasmodium falciparum potassium channel 0.0136 0.0206 1
Echinococcus multilocularis nibrin 0.0052 0.0039 0.0034
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0136 0.0206 0.1226
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0015 0.007
Brugia malayi Bromodomain containing protein 0.004 0.0016 0.0057
Plasmodium falciparum replication factor C subunit 1, putative 0.0052 0.0039 0.1492
Schistosoma mansoni calcium-activated potassium channel 0.0136 0.0206 0.0249
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0085 0.0106 0.0123
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.001 0.0119
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0076 0.0086
Loa Loa (eye worm) hypothetical protein 0.0044 0.0025 0.0023
Echinococcus granulosus importin subunit beta 1 0.0061 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Loa Loa (eye worm) hypothetical protein 0.1398 0.2697 0.3344
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0037 0.001 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0085 0.0106 0.061
Echinococcus granulosus potassium channel subfamily K 8 0.0136 0.0206 0.0249
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.009 0.406
Brugia malayi conserved hypotetical protein 0.004 0.0017 0.0061
Entamoeba histolytica acyl-coA synthetase, putative 0.0125 0.0184 0.1539
Loa Loa (eye worm) hypothetical protein 0.0072 0.008 0.009
Echinococcus granulosus FTZ F1 alpha 0.0085 0.0106 0.0125
Toxoplasma gondii patched family protein 0.0038 0.0012 0.0233
Plasmodium vivax ataxin-2 like protein, putative 0.0077 0.009 0.406
Schistosoma mansoni hypothetical protein 0.0065 0.0066 0.0074
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0024
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0136 0.0206 0.1226
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.0214 0.1276
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Schistosoma mansoni topbp1 0.0052 0.0039 0.0042
Mycobacterium leprae conserved hypothetical protein 0.0072 0.008 0.4233
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0085 0.0106 0.061
Brugia malayi Pax transcription activation domain interacting protein 0.0052 0.0039 0.0199
Schistosoma mansoni tar DNA-binding protein 0.007 0.0076 0.0088
Trypanosoma cruzi FHA domain containing protein, putative 0.0052 0.0039 0.162
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0024
Schistosoma mansoni inositol monophosphatase 0.0037 0.001 0.0006
Echinococcus granulosus twik family of potassium channels 0.0136 0.0206 0.0249
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0035 0.0148
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.001 0.0029
Loa Loa (eye worm) hypothetical protein 0.1323 0.2548 0.3158
Schistosoma mansoni hypothetical protein 0.0065 0.0066 0.0074
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0228 0.0387 0.0473
Loa Loa (eye worm) hypothetical protein 0.0125 0.0184 0.022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0085 0.0106 0.0123
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.0113 0.0133
Echinococcus granulosus Protein patched homolog 1 0.0266 0.0462 0.0567
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0619 0.1159 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Schistosoma mansoni hypothetical protein 0.0256 0.0443 0.0543
Echinococcus multilocularis FTZ F1 alpha 0.0085 0.0106 0.01
Loa Loa (eye worm) inositol-1 0.0037 0.001 0.0004
Onchocerca volvulus 0.0038 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0619 0.1159 0.1432
Schistosoma mansoni calcium-activated potassium channel 0.4112 0.8051 1
Onchocerca volvulus 0.0136 0.0206 0.1057
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0052 0.0039 0.2009
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0028 0.0023
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.004 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.004
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Schistosoma mansoni hypothetical protein 0.014 0.0214 0.0259
Echinococcus multilocularis GPCR, family 2 0.0065 0.0066 0.006
Leishmania major GTP-binding protein, putative 0.0045 0.0026 0.0934
Schistosoma mansoni tar DNA-binding protein 0.007 0.0076 0.0088
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0015 0.0261
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0141 0.0215 0.026
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.009 0.4149
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0136 0.0206 0.1226
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0085 0.0106 0.0125
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0007 0.0002
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.006 0.0068
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0045 0.0027 0.0026
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0136 0.0206 0.1726
Onchocerca volvulus 0.0038 0.0012 0.0009
Brugia malayi hypothetical protein 0.005 0.0036 0.0177
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0136 0.0206 0.0247
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.001 0.0171
Schistosoma mansoni hypothetical protein 0.0228 0.0387 0.0473
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.001 0.0018
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.008 0.0442
Onchocerca volvulus 0.0136 0.0206 0.1057
Schistosoma mansoni hypothetical protein 0.0256 0.0443 0.0543
Brugia malayi CHE-14 protein 0.0266 0.0462 0.2804
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.001 0.0119
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0015 0.1635
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0037 0.001 0.0119
Echinococcus granulosus replication factor c subunit 1 0.0052 0.0039 0.0042
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0085 0.0106 0.0125
Brugia malayi Patched related family protein 10 0.0038 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Loa Loa (eye worm) hypothetical protein 0.0042 0.0021 0.0018
Brugia malayi Nuclear hormone receptor E75 0.004 0.0017 0.0061
Loa Loa (eye worm) hypothetical protein 0.0141 0.0215 0.0259
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0125 0.0184 0.1108
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.001 0.0003
Echinococcus multilocularis tar DNA binding protein 0.007 0.0076 0.0071
Leishmania major hypothetical protein, conserved 0.0077 0.009 0.4149
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Echinococcus granulosus microtubule associated protein 2 0.2798 0.5458 0.6777
Schistosoma mansoni nuclear receptor nhr-48 0.004 0.0017 0.0014
Brugia malayi Steroid receptor seven-up type 2 0.0085 0.0106 0.061
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0085 0.0106 0.061
Toxoplasma gondii hypothetical protein 0.0038 0.0012 0.0233
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0015 0.0408
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0015 0.0408
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0045 0.0026 0.0114
Brugia malayi Calcitonin receptor-like protein seb-1 0.0205 0.0342 0.2064
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0028 0.0023
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0015 0.0012
Onchocerca volvulus Protein patched homolog 0.0038 0.0012 0.0009
Loa Loa (eye worm) patched family protein 0.0038 0.0012 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0136 0.0206 1
Leishmania major calcium/potassium channel (CAKC), putative 0.0136 0.0206 1
Echinococcus multilocularis potassium channel subfamily K 0.0136 0.0206 0.02
Trypanosoma cruzi ion transport protein, putative 0.0136 0.0206 1
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.004 0.0017 0.0014
Plasmodium vivax patched family protein, putative 0.0038 0.0012 0.0084
Brugia malayi nuclear hormone receptor 0.0085 0.0106 0.061
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0028 0.0028
Brugia malayi Pre-SET motif family protein 0.0857 0.1629 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.004
Loa Loa (eye worm) hypothetical protein 0.0072 0.008 0.009
Onchocerca volvulus 0.0072 0.008 0.0376
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0076 0.0428
Leishmania major hypothetical protein, conserved 0.0136 0.0206 1
Schistosoma mansoni topbp1 0.0052 0.0039 0.0042
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0028 0.0028
Onchocerca volvulus 0.0136 0.0206 0.1057
Schistosoma mansoni alpha-glucosidase 0.0137 0.0207 0.025
Echinococcus multilocularis Nuclear hormone receptor HR96 0.004 0.0017 0.0011
Brugia malayi Inositol-1 0.0037 0.001 0.0021
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.008 0.0943
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.008 0.0074
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0052 0.0039 0.162
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Entamoeba histolytica hypothetical protein 0.0228 0.0387 0.3294
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0125 0.0184 0.1108
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0125 0.0184 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0085 0.0106 0.061
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0015 0.018
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0125 0.0184 0.2181
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi hypothetical protein 0.0136 0.0206 0.1226
Loa Loa (eye worm) hypothetical protein 0.014 0.0214 0.0257
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.001 0.0006
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.008 0.0943
Toxoplasma gondii ATPase, AAA family protein 0.0052 0.0039 0.1621
Schistosoma mansoni glutaminase 0.0834 0.1584 0.1961
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Brugia malayi Importin beta-1 subunit 0.0061 0.0057 0.0309
Onchocerca volvulus 0.0136 0.0206 0.1057
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0045 0.0026 0.0934
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0136 0.0206 0.0247
Loa Loa (eye worm) hypothetical protein 0.0037 0.001 0.0004
Brugia malayi AMP-binding enzyme family protein 0.0037 0.001 0.0018
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0011 0.0007
Loa Loa (eye worm) nuclear hormone receptor 0.004 0.0017 0.0012
Schistosoma mansoni tar DNA-binding protein 0.007 0.0076 0.0088
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0052 0.0039 0.028
Brugia malayi AMP-binding enzyme family protein 0.0125 0.0184 0.1093
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0039 0.0174
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0052 0.0039 0.0174
Mycobacterium tuberculosis Possible penicillin-binding protein 0.046 0.0845 1
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0011 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0085 0.0106 0.061
Loa Loa (eye worm) hypothetical protein 0.015 0.0233 0.0281
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Schistosoma mansoni nuclear receptor 0.004 0.0017 0.0014
Brugia malayi hypothetical protein 0.0052 0.0039 0.0199
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Onchocerca volvulus 0.0092 0.0119 0.0586
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0085 0.0106 0.0125
Schistosoma mansoni hypothetical protein 0.0136 0.0206 0.0249
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0028 0.0132
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0015 0.0408
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0045 0.0027 0.0021
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0052 0.0039 0.0174
Toxoplasma gondii LsmAD domain-containing protein 0.0077 0.009 0.4149
Brugia malayi protein C24B5.3 0.0038 0.0012 0.0029
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0136 0.0206 0.1226
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0085 0.0106 0.061
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Onchocerca volvulus Bile acid receptor homolog 0.0085 0.0106 0.0518
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0011 0.0006
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0024
Schistosoma mansoni calcium-activated potassium channel 0.0136 0.0206 0.0249
Plasmodium vivax acyl-CoA synthetase, putative 0.0093 0.0122 0.5713
Brugia malayi AMP-binding enzyme family protein 0.0125 0.0184 0.1093
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.001 0.0151
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0052 0.0039 0.0174
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0123 0.018 0.8707
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0015 0.005
Trypanosoma brucei calcium-activated potassium channel, putative 0.0136 0.0206 1
Schistosoma mansoni patched 1 0.0266 0.0462 0.0567
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0136 0.0206 0.1226
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Echinococcus granulosus nuclear receptor nhr 48 0.004 0.0017 0.0014
Loa Loa (eye worm) uncoordinated protein 58 0.0136 0.0206 0.0247
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0136 0.0206 0.1226
Loa Loa (eye worm) hypothetical protein 0.0072 0.008 0.009
Brugia malayi nuclear receptor RXR 0.0045 0.0027 0.012
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0037 0.001 0.0151
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi TAR-binding protein 0.007 0.0076 0.0428
Plasmodium falciparum potassium channel 0.0136 0.0206 1
Schistosoma mansoni nuclear hormone receptor 0.004 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0085 0.0106 0.0125
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0045 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0045 0.0027 0.0026
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0045 0.0026 0.002
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.008 0.0391
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0136 0.0206 0.1072
Mycobacterium tuberculosis Conserved protein 0.0072 0.008 0.0943
Schistosoma mansoni tar DNA-binding protein 0.007 0.0076 0.0088
Plasmodium falciparum lipid/sterol:H+ symporter 0.0038 0.0012 0.0084
Brugia malayi DKFZp564C0469 protein 0.0052 0.0039 0.0199
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0045 0.0026 0.0934
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0136 0.0206 0.1072
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.004 0.0017 0.0011
Loa Loa (eye worm) hypothetical protein 0.0266 0.0462 0.0565
Echinococcus granulosus twik family of potassium channels 0.0136 0.0206 0.0249
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0228 0.0387 0.0381
Loa Loa (eye worm) DR-78 0.004 0.0017 0.0012
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.001 0.0171
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0037 0.001 0.0018
Trichomonas vaginalis ran, putative 0.0045 0.0026 0.01
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Echinococcus multilocularis tumor protein p63 0.1024 0.1958 0.1953
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0028 0.0027
Loa Loa (eye worm) beta-lactamase 0.0072 0.008 0.009
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0057 0.2521
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0125 0.0184 0.8914
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0037 0.001 0.0026
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.008 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0039 0.0174
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0045 0.0026 0.0795
Toxoplasma gondii patched family protein 0.0038 0.0012 0.0233
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0251 0.0245
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0057 0.2521
Echinococcus multilocularis small conductance calcium activated potassium 0.4112 0.8051 0.805
Loa Loa (eye worm) hypothetical protein 0.0093 0.0122 0.0143
Schistosoma mansoni steroid hormone receptor ad4bp 0.0085 0.0106 0.0125
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Toxoplasma gondii patched family protein 0.0038 0.0012 0.0233
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0136 0.0206 0.1226
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0011 0.0058
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.001 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0085 0.0106 0.061
Echinococcus granulosus GTP binding nuclear protein Ran 0.0045 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Echinococcus granulosus Nuclear hormone receptor HR96 0.004 0.0017 0.0014
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Plasmodium falciparum acyl-CoA synthetase 0.0093 0.0122 0.5713
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0136 0.0206 0.1072
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.001 0.0004
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0159 0.0252 0.0246
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0037 0.001 0.0119
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0037 0.001 0.0151
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.004 0.0017 0.0038
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0136 0.0206 0.1226
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0085 0.0106 0.01
Trypanosoma cruzi hypothetical protein, conserved 0.0136 0.0206 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0125 0.0184 0.1539
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0125 0.0184 1
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Leishmania major ion transport protein-like protein 0.0136 0.0206 1
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.008 0.0391
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.001 0.0399
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.0251 0.0304
Schistosoma mansoni hypothetical protein 0.0379 0.0685 0.0844
Schistosoma mansoni acetyl-CoA synthetase 0.0037 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.0251 0.1501
Onchocerca volvulus 0.0136 0.0206 0.1057
Schistosoma mansoni importin beta-1 0.0061 0.0057 0.0064
Mycobacterium ulcerans transmembrane cation transporter 0.0136 0.0206 0.1245
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.001 0.0151
Plasmodium vivax SET domain protein, putative 0.0123 0.018 0.8688
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0085 0.0106 0.0125
Brugia malayi hypothetical protein 0.0077 0.009 0.0509
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0037 0.001 0.0018
Schistosoma mansoni retinoic acid receptor RXR 0.0204 0.0341 0.0417
Loa Loa (eye worm) hypothetical protein 0.1255 0.2414 0.2992
Brugia malayi Bromodomain containing protein 0.0078 0.0092 0.0522
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0112 0.1324
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0251 0.0245
Loa Loa (eye worm) glutaminase 0.0834 0.1584 0.196
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0204 0.0341 0.0417
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0085 0.0106 0.0125
Treponema pallidum DNA ligase (lig) 0.0052 0.0039 1
Leishmania major potassium channel subunit-like protein 0.0136 0.0206 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0085 0.0106 0.0125
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0136 0.0206 0.0249
Leishmania major hypothetical protein, conserved 0.0037 0.0011 0.0207
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0015 0.001
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0125 0.0184 0.1108
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.004
Loa Loa (eye worm) RNA binding protein 0.007 0.0076 0.0086
Onchocerca volvulus 0.015 0.0233 0.1205
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0136 0.0206 0.1226
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Onchocerca volvulus 0.0072 0.008 0.0376
Loa Loa (eye worm) hypothetical protein 0.0093 0.0122 0.0143
Brugia malayi orphan nuclear receptor NR2E1 0.004 0.0017 0.0061
Echinococcus multilocularis snurportin 1 0.0647 0.1214 0.1209
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.0011 0.0207
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.001 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0037 0.001 0.0018
Echinococcus granulosus sterol regulatory element binding protein 0.0266 0.0462 0.0567
Mycobacterium ulcerans beta-lactamase 0.0072 0.008 0.0442
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.001 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0039 0.0174
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi nuclear receptor RXR 0.004 0.0017 0.0061
Plasmodium vivax importin-beta 2, putative 0.0061 0.0057 0.2407
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0205 0.0342 0.2064
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0037 0.001 0.0119
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0647 0.1214 0.1501
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi ecdysteroid receptor 0.0085 0.0106 0.061
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0085 0.0106 0.01
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0015 0.0261
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Brugia malayi Patched related family protein 12 0.0038 0.0012 0.0029
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0045 0.0026 0.0795
Onchocerca volvulus 0.0072 0.008 0.0376
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0028 0.0028
Brugia malayi Patched protein homolog 1 0.0038 0.0012 0.0029
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.001 0.0171
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.001 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0028 0.0028
Echinococcus multilocularis twik family of potassium channels 0.0136 0.0206 0.02
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0045 0.0027 0.0024
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0026 0.0934
Onchocerca volvulus 0.0038 0.0012 0.0009
Trichomonas vaginalis set domain proteins, putative 0.0976 0.1863 1
Toxoplasma gondii exonuclease III APE 0.0039 0.0015 0.0408
Leishmania major hypothetical protein, conserved 0.0072 0.008 0.3651
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.009 0.4149
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0045 0.0026 0.0548
Loa Loa (eye worm) hypothetical protein 0.0061 0.0057 0.0062
Schistosoma mansoni coup transcription factor 0.0085 0.0106 0.0125
Brugia malayi tailless protein 0.004 0.0017 0.0061
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0007 0.0001
Mycobacterium leprae Probable lipase LipE 0.0072 0.008 0.4233
Schistosoma mansoni hypothetical protein 0.0256 0.0443 0.0543
Trichomonas vaginalis importin beta-1, putative 0.0049 0.0035 0.0148
Loa Loa (eye worm) hypothetical protein 0.0072 0.008 0.009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0085 0.0106 0.0123
Plasmodium vivax potassium channel, putative 0.0136 0.0206 1
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0039 0.0174
Entamoeba histolytica hypothetical protein 0.0228 0.0387 0.3294
Echinococcus multilocularis potassium channel subfamily K 8 0.0136 0.0206 0.02
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0085 0.0106 0.01
Trichomonas vaginalis glutaminase, putative 0.0834 0.1584 0.8496
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi ecdysone receptor 0.004 0.0017 0.0061
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0136 0.0206 0.2437
Mycobacterium ulcerans glutaminase 0.0834 0.1584 1
Brugia malayi Myosin head containing protein 0.0038 0.0012 0.0029
Brugia malayi Niemann-Pick C1 protein precursor 0.0619 0.1159 0.7104
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.006 0.0055
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.0011 0.0207
Entamoeba histolytica hypothetical protein 0.0049 0.0035 0.0239
Onchocerca volvulus 0.0038 0.0012 0.0009
Schistosoma mansoni bromodomain containing protein 0.0066 0.0068 0.0077
Schistosoma mansoni hypothetical protein 0.0256 0.0443 0.0543
Brugia malayi hypothetical protein 0.0136 0.0206 0.1226
Brugia malayi steroid hormone receptor 0.0085 0.0106 0.061
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.008 0.009
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0066 0.006
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0015 0.0044
Loa Loa (eye worm) oxidoreductase 0.0037 0.001 0.0004
Brugia malayi hypothetical protein 0.0038 0.0012 0.0029
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.001 0.0171
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Schistosoma mansoni microtubule-associated protein tau 0.2798 0.5458 0.6777
Echinococcus multilocularis nuclear receptor nhr 48 0.004 0.0017 0.0011
Trypanosoma cruzi ion transport protein, putative 0.0136 0.0206 1
Echinococcus granulosus small conductance calcium activated potassium 0.4112 0.8051 1
Schistosoma mansoni chromosome transmission fidelity factor 0.0052 0.0039 0.0042
Plasmodium vivax replication factor C subunit 1, putative 0.0052 0.0039 0.1492
Onchocerca volvulus 0.0038 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0072 0.008 0.009
Trichomonas vaginalis esterase, putative 0.0072 0.008 0.0391
Brugia malayi hypothetical protein 0.0038 0.0012 0.0029
Schistosoma mansoni transcription factor LCR-F1 0.0228 0.0387 0.0473
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.008 0.0092
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Loa Loa (eye worm) nuclear receptor NHR-67 0.004 0.0017 0.0012
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0027 0.012
Toxoplasma gondii ion channel protein 0.0136 0.0206 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0141 0.0215 0.026
Toxoplasma gondii ion channel protein 0.0136 0.0206 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0141 0.0215 0.021
Echinococcus granulosus Niemann Pick C1 protein 0.0619 0.1159 0.1434
Loa Loa (eye worm) hypothetical protein 0.0065 0.0066 0.0073
Brugia malayi nuclear receptor NHR-88 0.0085 0.0106 0.061
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0379 0.0685 0.068
Loa Loa (eye worm) hypothetical protein 0.004 0.0016 0.0012
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0136 0.0206 0.1226
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0039 0.0174
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.004
Brugia malayi hypothetical protein 0.004 0.0017 0.0061
Mycobacterium tuberculosis Conserved protein 0.0072 0.008 0.0943
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.008 0.0448
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0085 0.0106 0.0123
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0085 0.0106 0.0125
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.008 0.0442
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0037 0.001 0.0151
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.001 0.0151
Plasmodium vivax hypothetical protein, conserved 0.0072 0.008 0.3553
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Schistosoma mansoni nuclear hormone receptor 0.0085 0.0106 0.0125
Schistosoma mansoni ran 0.0045 0.0026 0.0025
Onchocerca volvulus 0.0038 0.0012 0.0009
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.004 0.0017 0.0014
Schistosoma mansoni nuclear hormone receptor 0.004 0.0017 0.0014
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0037 0.001 0.0005
Entamoeba histolytica Ran family GTPase 0.0045 0.0026 0.0161
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.001 0.0171
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0027 0.012
Schistosoma mansoni ran 0.0045 0.0026 0.0025
Echinococcus multilocularis twik family of potassium channels 0.0136 0.0206 0.02
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0085 0.0106 0.0125
Echinococcus multilocularis calcium activated potassium channel variant 0.0136 0.0206 0.02
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.004 0.0017 0.0038
Plasmodium vivax potassium channel, putative 0.0136 0.0206 1
Loa Loa (eye worm) TWK-7 protein 0.0136 0.0206 0.0247
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0085 0.0106 0.0123
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.008 0.0943
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0085 0.0106 0.01
Loa Loa (eye worm) steroid hormone receptor 0.0085 0.0106 0.0123
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0015 0.0032
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0037 0.001 0.0119
Loa Loa (eye worm) hypothetical protein 0.0093 0.0122 0.0143
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0052 0.0039 0.0199
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Echinococcus multilocularis Niemann Pick C1 protein 0.0885 0.1684 0.1679
Loa Loa (eye worm) hypothetical protein 0.0325 0.058 0.0712
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0123 0.018 0.0217
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0052 0.0039 0.162
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0024
Onchocerca volvulus 0.0976 0.1863 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.001 0.0004
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.001 0.0119
Echinococcus granulosus tar DNA binding protein 0.007 0.0076 0.0088
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.001 0.0016
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0136 0.0206 1
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0136 0.0206 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.0083 0.0094
Echinococcus granulosus tumor protein p63 0.1024 0.1958 0.2427
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0125 0.0184 0.2181
Echinococcus granulosus GPCR family 2 0.0065 0.0066 0.0074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0085 0.0106 0.0123
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0026 0.0934
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Brugia malayi Pre-SET motif family protein 0.0123 0.018 0.1068
Mycobacterium ulcerans lipase LipD 0.0072 0.008 0.0442
Echinococcus multilocularis sterol regulatory element binding protein 0.0266 0.0462 0.0456
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.4112 0.8051 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0205 0.0342 0.0416
Loa Loa (eye worm) patched family protein 0.0038 0.0012 0.0006
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0052 0.0039 0.0174
Schistosoma mansoni hypothetical protein 0.0065 0.0066 0.0074
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Brugia malayi nuclear hormone receptor 0.004 0.0017 0.0061
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0136 0.0206 0.1226
Echinococcus granulosus ecdysone induced protein 78C 0.0085 0.0106 0.0125
Echinococcus multilocularis thyroid hormone receptor alpha 0.0464 0.0853 0.0848
Mycobacterium ulcerans acyl-CoA synthetase 0.0125 0.0184 0.1108
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0136 0.0206 0.1226
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0085 0.0106 0.0125
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0035 0.0148
Loa Loa (eye worm) TWK-28 protein 0.0136 0.0206 0.0247
Echinococcus multilocularis expressed conserved protein 0.0582 0.1085 0.108
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0136 0.0206 0.0247
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.008 0.0391
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0085 0.0106 0.01
Echinococcus multilocularis replication factor c subunit 1 0.0052 0.0039 0.0034
Echinococcus granulosus histone lysine methyltransferase setb 0.0141 0.0215 0.026
Brugia malayi protein C24B5.3 0.0038 0.0012 0.0029
Schistosoma mansoni calcium-activated potassium channel 0.2653 0.5173 0.6422
Echinococcus granulosus Niemann Pick C1 protein 0.0885 0.1684 0.2085
Schistosoma mansoni cellular tumor antigen P53 0.015 0.0233 0.0283
Brugia malayi hypothetical protein 0.0168 0.0269 0.1613
Brugia malayi hypothetical protein 0.004 0.0017 0.0061
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Schistosoma mansoni thyroid hormone receptor 0.0464 0.0853 0.1053
Loa Loa (eye worm) hypothetical protein 0.0205 0.0342 0.0416
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Giardia lamblia Hypothetical protein 0.0136 0.0206 1
Brugia malayi hypothetical protein 0.0228 0.0387 0.234
Brugia malayi AMP-binding enzyme family protein 0.0037 0.001 0.0018
Leishmania major 4-coumarate:coa ligase-like protein 0.0125 0.0184 0.8914
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0003 0.0034
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Echinococcus multilocularis potassium channel subfamily K 8 0.0136 0.0206 0.02
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Onchocerca volvulus 0.0125 0.0184 0.0941
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.008 0.3651
Brugia malayi hypothetical protein 0.0052 0.0039 0.0199
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0136 0.0206 0.02
Brugia malayi hypothetical protein 0.0045 0.0027 0.012
Echinococcus multilocularis microtubule associated protein 2 0.2798 0.5458 0.5455
Onchocerca volvulus 0.0136 0.0206 0.1057
Brugia malayi Augmenter of liver regeneration 0.0037 0.0011 0.0025
Loa Loa (eye worm) hypothetical protein 0.0093 0.0122 0.0143
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0037 0.001 0.0119
Schistosoma mansoni zinc finger protein 0.004 0.0017 0.0014
Schistosoma mansoni hypothetical protein 0.0647 0.1214 0.1502
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0085 0.0106 0.061
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0052 0.0039 0.162
Echinococcus granulosus potassium channel subfamily K 0.0136 0.0206 0.0249
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi Nuclear hormone receptor E75 0.004 0.0017 0.0061
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0136 0.0206 0.1226
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0112 0.1324
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0037 0.001 0.0119
Mycobacterium ulcerans acyl-CoA synthetase 0.0125 0.0184 0.1108
Leishmania major importin beta-1 subunit, putative 0.0049 0.0035 0.1384
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0136 0.0206 0.1226
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Onchocerca volvulus 0.0123 0.018 0.0918
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Trichomonas vaginalis replication factor C large subunit, putative 0.0052 0.0039 0.0174
Loa Loa (eye worm) glutaminase 2 0.0834 0.1584 0.196
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.008 0.0391
Echinococcus granulosus potassium channel subfamily K 8 0.0136 0.0206 0.0249
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.008 0.0943
Toxoplasma gondii propionate-CoA ligase 0.0037 0.001 0.0151
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0125 0.0184 0.1108
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0085 0.0106 0.061
Schistosoma mansoni inositol monophosphatase 0.0037 0.001 0.0006
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.008 0.0943
Loa Loa (eye worm) nuclear receptor nhr-7B 0.004 0.0017 0.0012
Schistosoma mansoni hypothetical protein 0.4112 0.8051 1
Schistosoma mansoni alpha glucosidase 0.0035 0.0007 0.0002
Brugia malayi topoisomerase 0.0052 0.0039 0.0199
Brugia malayi RNA, U transporter 1 0.0172 0.0278 0.1668
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0136 0.0206 1
Loa Loa (eye worm) patched family protein 0.0038 0.0012 0.0006
Brugia malayi RNA binding protein 0.007 0.0076 0.0428
Echinococcus multilocularis protein dispatched 1 0.0303 0.0536 0.0531
Toxoplasma gondii ABC1 family protein 0.0072 0.008 0.3651
Onchocerca volvulus 0.004 0.0017 0.0038
Schistosoma mansoni ap endonuclease 0.0039 0.0015 0.0012

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 21.8724 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 38.8952 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 43.2771 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 43.6412 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of thyroid hormone receptor beta signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 48.5577 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 54.941 uM PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 61.1306 uM PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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