Detailed information for compound 557198

Basic information

Technical information
  • TDR Targets ID: 557198
  • Name: (9E,11E,15E)-13-hydroperoxyoctadeca-9,11,15-t rienoic acid
  • MW: 310.428 | Formula: C18H30O4
  • H donors: 2 H acceptors: 3 LogP: 4.83 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC/C=C/CC(C=CC=CCCCCCCCC(=O)O)OO
  • InChi: 1S/C18H30O4/c1-2-3-11-14-17(22-21)15-12-9-7-5-4-6-8-10-13-16-18(19)20/h3,7,9,11-12,15,17,21H,2,4-6,8,10,13-14,16H2,1H3,(H,19,20)/b9-7+,11-3+,15-12+
  • InChiKey: UYQGVDXDXBAABN-YPPMWDAJSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 13-hydroperoxy-9,11,15-octadecatrienoic acid
  • 28836-09-1
  • 9,11,15-Octadecatrienoic acid, 13-hydroperoxy-, (E,Z,Z)-
  • 13-Hpot

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni amine GPCR 0.0194 0.0711 0.0711
Echinococcus granulosus geminin 0.0369 0.1375 0.1375
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0009 0.001 0.001
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1287 0.4863 0.4863
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0194 0.0711 0.0711
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0193 0.0708 1
Schistosoma mansoni hypothetical protein 0.0061 0.0206 0.0206
Echinococcus multilocularis cysteine protease 0.0009 0.001 0.001
Brugia malayi Sulfatase family protein 0.001 0.0012 0.0028
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0035 0.0107 0.0248
Trypanosoma brucei C-8 sterol isomerase, putative 0.0464 0.1738 1
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Echinococcus granulosus neuropeptide receptor 0.0194 0.0711 0.0711
Onchocerca volvulus 0.0021 0.0055 0.0106
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0028 0.0119
Loa Loa (eye worm) neuropeptide F receptor 0.0194 0.0711 0.0711
Brugia malayi Pre-SET motif family protein 0.0057 0.0191 0.0444
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0015 0.0033 0.0053
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1764 0.6672 0.6672
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0194 0.0711 0.0711
Echinococcus granulosus 7tm_1 domain containing protein 0.0194 0.0711 0.0711
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0051 0.0168 0.0168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0193 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0186 0.0683 0.0683
Onchocerca volvulus 0.0057 0.0191 0.0421
Echinococcus multilocularis neuropeptide Y receptor 0.0194 0.0711 0.0711
Onchocerca volvulus 0.0194 0.0711 0.1635
Brugia malayi follicle stimulating hormone receptor 0.0194 0.0711 0.1654
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0193 0.0708 0.0708
Onchocerca volvulus 0.0194 0.0711 0.1635
Loa Loa (eye worm) hypothetical protein 0.0193 0.0708 0.0708
Giardia lamblia Hypothetical protein 0.001 0.0012 0.0145
Echinococcus granulosus lamin 0.0021 0.0055 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0012
Schistosoma mansoni microtubule-associated protein tau 0.0944 0.3559 0.3559
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0035 0.0107 0.0107
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0194 0.0711 0.1654
Echinococcus multilocularis cathepsin L cysteine protease 0.0009 0.001 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0194 0.0711 0.0711
Schistosoma mansoni growth hormone secretagogue receptor 0.0194 0.0711 0.0711
Onchocerca volvulus 0.0194 0.0711 0.1635
Echinococcus granulosus survival motor neuron protein 1 0.0186 0.0683 0.0683
Toxoplasma gondii hypothetical protein 0.0193 0.0708 1
Schistosoma mansoni amine GPCR 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0012
Echinococcus granulosus bloom syndrome protein 0.0016 0.0036 0.0036
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0058 0.0196 0.4607
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0194 0.0711 0.0711
Trichomonas vaginalis DNA helicase recq, putative 0.0016 0.0036 0.0171
Trichomonas vaginalis DNA helicase recq1, putative 0.0016 0.0036 0.0171
Mycobacterium tuberculosis Conserved hypothetical protein 0.0015 0.0033 0.0558
Loa Loa (eye worm) serotonin transporter b 0.1138 0.4296 0.4296
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0193 0.0708 0.1648
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0222 0.0819 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0014 0.0028 0.0215
Loa Loa (eye worm) hypothetical protein 0.0193 0.0708 0.0708
Echinococcus multilocularis neuropeptide Y receptor 0.0194 0.0711 0.0711
Entamoeba histolytica hypothetical protein 0.0051 0.0168 0.1976
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Brugia malayi map kinase activated protein kinase protein 2 0.0734 0.2764 0.6433
Echinococcus multilocularis neuropeptide receptor A26 0.0544 0.204 0.204
Loa Loa (eye worm) hypothetical protein 0.0193 0.0708 0.0708
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.0014
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0014 0.0029 0.0406
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0464 0.1738 0.4046
Echinococcus granulosus tachykinin peptides receptor 99D 0.0194 0.0711 0.0711
Echinococcus multilocularis serotonin receptor 0.264 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.0009 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0061 0.0206 0.0206
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0222 0.0819 1
Loa Loa (eye worm) ctsf protein 0.0009 0.001 0.001
Trichomonas vaginalis set domain proteins, putative 0.0451 0.1689 1
Trichomonas vaginalis glutaminase, putative 0.0208 0.0765 0.4503
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0058 0.0196 0.2769
Brugia malayi AKH receptor 0.0194 0.0711 0.1654
Brugia malayi Cytochrome P450 family protein 0.0014 0.0028 0.0065
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0194 0.0711 0.1654
Echinococcus multilocularis sex peptide receptor 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Echinococcus multilocularis g protein coupled receptor 0.0194 0.0711 0.0711
Echinococcus granulosus fmrfamide receptor 0.0194 0.0711 0.0711
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0058 0.0196 0.2666
Loa Loa (eye worm) hypothetical protein 0.0193 0.0708 0.0708
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0222 0.0819 0.4828
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Onchocerca volvulus 0.0194 0.0711 0.1635
Brugia malayi hypothetical protein 0.0051 0.0168 0.0391
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.0014
Echinococcus multilocularis geminin 0.0369 0.1375 0.1375
Echinococcus granulosus allatostatin A receptor 0.0194 0.0711 0.0711
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0009 0.001 0.0014
Echinococcus granulosus g protein coupled receptor 0.0194 0.0711 0.0711
Onchocerca volvulus 0.0194 0.0711 0.1635
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0734 0.2764 0.2764
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0194 0.0711 0.0711
Onchocerca volvulus 0.0194 0.0711 0.1635
Schistosoma mansoni hypothetical protein 0.0061 0.0206 0.0206
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0734 0.2764 0.2764
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Echinococcus granulosus sodium and chloride dependent glycine 0.0193 0.0708 0.0708
Schistosoma mansoni apoptosis regulator bax 0.0061 0.0206 0.0206
Brugia malayi Dopamine receptor 0.0194 0.0711 0.1654
Loa Loa (eye worm) hypothetical protein 0.0015 0.0033 0.0033
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0032 0.0098 0.0098
Schistosoma mansoni amine GPCR 0.0194 0.0711 0.0711
Schistosoma mansoni adenoreceptor 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0193 0.0708 0.1648
Echinococcus multilocularis rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Brugia malayi Dopamine receptor protein 2 0.0194 0.0711 0.1654
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0194 0.0711 0.0711
Loa Loa (eye worm) norepinephrine transporter 0.1138 0.4296 0.4296
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0222 0.0819 0.4828
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0194 0.0711 0.0711
Echinococcus multilocularis conserved hypothetical protein 0.0693 0.2605 0.2605
Echinococcus multilocularis microtubule associated protein 2 0.0944 0.3559 0.3559
Echinococcus granulosus tm gpcr rhodopsin 0.0194 0.0711 0.0711
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0061 0.0206 0.0206
Loa Loa (eye worm) solute carrier family 6 member 4 0.1138 0.4296 0.4296
Brugia malayi hypothetical protein 0.0194 0.0711 0.1654
Brugia malayi hypothetical protein 0.001 0.0012 0.0028
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Entamoeba histolytica hypothetical protein 0.0051 0.0168 0.1976
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Echinococcus multilocularis serotonin transporter 0.1138 0.4296 0.4296
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Onchocerca volvulus 0.0194 0.0711 0.1635
Schistosoma mansoni sodium-dependent amino acid transporter 0.0193 0.0708 0.0708
Echinococcus granulosus dro:myosuppressin receptor 0.0194 0.0711 0.0711
Echinococcus granulosus cytoplasmic intermediate filament protein 0.001 0.0014 0.0014
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Echinococcus granulosus rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0193 0.0708 0.0708
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0193 0.0708 0.0708
Mycobacterium ulcerans endonuclease IV 0.0058 0.0196 0.2447
Schistosoma mansoni neuropeptide f receptor 76f 0.0194 0.0711 0.0711
Giardia lamblia Fructose-bisphosphate aldolase 0.0222 0.0819 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0194 0.0711 0.0711
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0109 0.0387 1
Brugia malayi Melatonin receptor type 1A 0.0194 0.0711 0.1654
Onchocerca volvulus 0.0194 0.0711 0.1635
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0028 0.0119
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.001 0.0012 0.0026
Schistosoma mansoni neuropeptide receptor 0.0194 0.0711 0.0711
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0222 0.0819 0.4828
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0194 0.0711 0.0711
Trypanosoma cruzi cysteine peptidase, putative 0.0009 0.001 0.0014
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0194 0.0711 0.0711
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0009 0.001 0.0014
Onchocerca volvulus 0.0194 0.0711 0.1635
Schistosoma mansoni blooms syndrome DNA helicase 0.0013 0.0023 0.0023
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0194 0.0711 0.0711
Echinococcus multilocularis somatostatin receptor 0.0194 0.0711 0.0711
Onchocerca volvulus 0.0194 0.0711 0.1635
Trypanosoma cruzi cysteine peptidase, putative 0.0009 0.001 0.0014
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0193 0.0708 0.0708
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0007 0.000000000011595 0.00000000016373
Loa Loa (eye worm) RecQ helicase 0.0016 0.0036 0.0036
Brugia malayi hypothetical protein 0.0139 0.0504 0.1172
Onchocerca volvulus Neuropeptide F receptor homolog 0.0194 0.0711 0.1635
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0222 0.0819 0.4828
Onchocerca volvulus 0.0038 0.0119 0.0254
Echinococcus granulosus g-protein coupled receptor 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0008 0.0005 0.0005
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0011 0.0018 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0009 0.001 0.003
Echinococcus multilocularis cysteine protease 0.0009 0.001 0.001
Onchocerca volvulus 0.0193 0.0708 0.1629
Schistosoma mansoni sodium/chloride dependent transporter 0.0195 0.0715 0.0715
Loa Loa (eye worm) hypothetical protein 0.0395 0.1475 0.1475
Echinococcus multilocularis neuropeptide s receptor 0.0544 0.204 0.204
Onchocerca volvulus 0.0194 0.0711 0.1635
Brugia malayi hypothetical protein 0.0194 0.0711 0.1654
Echinococcus multilocularis fmrfamide receptor 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0575 0.2157 0.2157
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0028 0.0081 0.0081
Brugia malayi Intermediate filament tail domain containing protein 0.0021 0.0055 0.0129
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0058 0.0196 0.0456
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0926 0.3491 0.8125
Echinococcus granulosus rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Brugia malayi Cathepsin L-like precursor 0.0009 0.001 0.0023
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0061 0.0206 0.0479
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.0014
Brugia malayi hypothetical protein 0.0194 0.0711 0.1654
Brugia malayi Bloom's syndrome protein homolog 0.0016 0.0036 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Giardia lamblia Hypothetical protein 0.001 0.0012 0.0145
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Toxoplasma gondii endonuclease IV APN 0.0058 0.0196 0.2769
Plasmodium vivax hypothetical protein, conserved 0.0193 0.0708 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0194 0.0711 0.0711
Echinococcus multilocularis bloom syndrome protein 0.0016 0.0036 0.0036
Echinococcus granulosus 7TM GPCR rhodopsin 0.0194 0.0711 0.0711
Leishmania major cathepsin L-like protease 0.0009 0.001 0.0014
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0193 0.0708 0.1648
Leishmania major cathepsin L-like protease 0.0009 0.001 0.0014
Onchocerca volvulus 0.0194 0.0711 0.1635
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0193 0.0708 0.0708
Echinococcus multilocularis survival motor neuron protein 1 0.0186 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Echinococcus granulosus intermediate filament protein 0.0021 0.0055 0.0055
Echinococcus multilocularis rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Echinococcus multilocularis g-protein coupled receptor 0.0194 0.0711 0.0711
Echinococcus granulosus biogenic amine 5HT receptor 0.1287 0.4863 0.4863
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0109 0.0387 0.4986
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0926 0.3491 0.3491
Brugia malayi hypothetical protein 0.0193 0.0708 0.1648
Brugia malayi putative neuropeptide receptor NPR1 0.0194 0.0711 0.1654
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0012
Brugia malayi G-protein coupled receptor 0.0194 0.0711 0.1654
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0009 0.001 0.0014
Echinococcus granulosus neuropeptide Y receptor 0.0194 0.0711 0.0711
Brugia malayi Cathepsin L-like precursor 0.0009 0.001 0.0023
Schistosoma mansoni neuropeptide receptor 0.0194 0.0711 0.0711
Echinococcus multilocularis rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Entamoeba histolytica hypothetical protein 0.0051 0.0168 0.1976
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0009 0.001 0.0014
Schistosoma mansoni neuropeptide F-like receptor 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Brugia malayi G protein-coupled receptor 0.0194 0.0711 0.1654
Loa Loa (eye worm) apoptosis regulator protein 0.0061 0.0206 0.0206
Onchocerca volvulus 0.0021 0.0055 0.0106
Echinococcus multilocularis rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Leishmania major cathepsin L-like protease 0.0009 0.001 0.0014
Brugia malayi neuropeptide F receptor 0.0194 0.0711 0.1654
Echinococcus multilocularis serotonin receptor 0.264 1 1
Echinococcus multilocularis neuropeptide receptor 0.0194 0.0711 0.0711
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0734 0.2764 0.2764
Brugia malayi Cathepsin L-like precursor 0.0009 0.001 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Plasmodium falciparum transporter, putative 0.0193 0.0708 1
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0091 0.0091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0009 0.001 0.0014
Treponema pallidum sodium- and chloride- dependent transporter 0.1138 0.4296 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0194 0.0711 0.0711
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Schistosoma mansoni lamin 0.0021 0.0055 0.0055
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0193 0.0708 1
Schistosoma mansoni biogenic amine receptor 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.1138 0.4296 0.4296
Brugia malayi RE15519p 0.0194 0.0711 0.1654
Schistosoma mansoni cathepsin F (C01 family) 0.0009 0.001 0.001
Loa Loa (eye worm) fibroinase 0.0009 0.001 0.001
Schistosoma mansoni amine GPCR 0.0194 0.0711 0.0711
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.0014
Loa Loa (eye worm) G-protein coupled receptor 0.0194 0.0711 0.0711
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0028 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.264 1 1
Leishmania major cathepsin L-like protease 0.0009 0.001 0.0014
Brugia malayi sulfakinin receptor protein 0.0395 0.1475 0.3433
Schistosoma mansoni neuropeptide receptor 0.0194 0.0711 0.0711
Echinococcus granulosus rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.001 0.0014 0.0014
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0015 0.0033 0.0076
Brugia malayi hypothetical protein 0.0186 0.0683 0.1589
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0008 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Echinococcus granulosus serotonin transporter 0.1138 0.4296 0.4296
Schistosoma mansoni transcription factor LCR-F1 0.0051 0.0168 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0194 0.0711 0.0711
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0194 0.0711 0.0711
Schistosoma mansoni neuropeptide receptor 0.0194 0.0711 0.0711
Schistosoma mansoni intermediate filament proteins 0.0021 0.0055 0.0055
Echinococcus granulosus tm gpcr rhodopsin 0.1913 0.7241 0.7241
Entamoeba histolytica hypothetical protein 0.0051 0.0168 0.1976
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Schistosoma mansoni survival motor neuron protein 0.0038 0.0119 0.0119
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0194 0.0711 0.0711
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0016 0.0222
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0191 0.0191
Echinococcus granulosus orexin receptor type 2 0.0194 0.0711 0.0711
Echinococcus multilocularis g protein coupled receptor 0.0194 0.0711 0.0711
Echinococcus granulosus rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Echinococcus multilocularis rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0194 0.0711 0.0711
Plasmodium falciparum cysteine proteinase falcipain 3 0.0009 0.001 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Brugia malayi hypothetical protein 0.0194 0.0711 0.1654
Echinococcus multilocularis lamin 0.0021 0.0055 0.0055
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0005 0.0005
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0011 0.0016 0.0091
Loa Loa (eye worm) hypothetical protein 0.0193 0.0708 0.0708
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0193 0.0708 0.0708
Schistosoma mansoni hypothetical protein 0.0038 0.0119 0.0119
Brugia malayi hypothetical protein 0.0194 0.0711 0.1654
Echinococcus multilocularis orexin receptor type 2 0.0194 0.0711 0.0711
Echinococcus multilocularis fmrfamide receptor 0.0194 0.0711 0.0711
Brugia malayi Dopamine receptor protein 1 0.0194 0.0711 0.1654
Leishmania major cytochrome p450-like protein 0.0014 0.0028 0.0119
Echinococcus multilocularis rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0193 0.0708 0.0708
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0194 0.0711 0.0711
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0028 0.0081 0.0189
Echinococcus granulosus voltage gated potassium channel 0.0008 0.0005 0.0005
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0194 0.0711 0.0711
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.001 0.0012 0.0026
Schistosoma mansoni hypothetical protein 0.0369 0.1375 0.1375
Echinococcus granulosus rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Echinococcus granulosus cathepsin l cysteine peptidase 0.0009 0.001 0.001
Echinococcus granulosus histone lysine methyltransferase setb 0.0057 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.264 1 1
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Echinococcus granulosus peptide allatostatin:somatostatin 0.0194 0.0711 0.0711
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0194 0.0711 0.0711
Brugia malayi hypothetical protein 0.0194 0.0711 0.1654
Loa Loa (eye worm) hypothetical protein 0.0363 0.1354 0.1354
Echinococcus multilocularis musashi 0.0021 0.0055 0.0055
Schistosoma mansoni glutaminase 0.0208 0.0765 0.0765
Brugia malayi G-protein coupled receptor 0.0194 0.0711 0.1654
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0194 0.0711 0.0711
Toxoplasma gondii cathepsin CPL 0.0009 0.001 0.014
Entamoeba histolytica cysteine proteinase, putative 0.0009 0.001 0.003
Schistosoma mansoni opsin-like receptor 0.0194 0.0711 0.0711
Schistosoma mansoni biogenic amine receptor 0.0194 0.0711 0.0711
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0057 0.0191 0.0191
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0091 0.0091
Mycobacterium ulcerans hypothetical protein 0.0015 0.0033 0.0278
Brugia malayi hypothetical protein 0.0194 0.0711 0.1654
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0194 0.0711 0.0711
Echinococcus granulosus somatostatin receptor 0.0194 0.0711 0.0711
Schistosoma mansoni myosin xvIII 0.0194 0.0711 0.0711
Mycobacterium ulcerans epimerase 0.0015 0.0033 0.0278
Echinococcus multilocularis sodium and chloride dependent glycine 0.0193 0.0708 0.0708
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0009 0.001 0.0014
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0009 0.001 0.014
Loa Loa (eye worm) hypothetical protein 0.0057 0.0191 0.0191
Echinococcus multilocularis g protein coupled receptor 0.0194 0.0711 0.0711
Schistosoma mansoni sodium/chloride dependent transporter 0.0193 0.0708 0.0708
Onchocerca volvulus 0.0194 0.0711 0.1635
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1138 0.4296 0.4296
Echinococcus granulosus sodium and chloride dependent glycine 0.0193 0.0708 0.0708
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0035 0.0107 0.0573
Entamoeba histolytica cysteine protease, putative 0.0009 0.001 0.003
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0074 0.0396
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Echinococcus multilocularis voltage gated potassium channel 0.0008 0.0005 0.0005
Echinococcus granulosus tm gpcr rhodopsin 0.1764 0.6672 0.6672
Echinococcus granulosus cathepsin L cysteine proteinase 0.0009 0.001 0.001
Onchocerca volvulus 0.0193 0.0708 0.1629
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Echinococcus granulosus g protein coupled receptor 0.0194 0.0711 0.0711
Echinococcus granulosus sex peptide receptor 0.0194 0.0711 0.0711
Schistosoma mansoni opsin-like receptor 0.0194 0.0711 0.0711
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0193 0.0708 0.0708
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0194 0.0711 0.0711
Brugia malayi GnHR receptor homolog 0.0194 0.0711 0.1654
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0028 0.0028
Echinococcus granulosus rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0193 0.0708 0.0708
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0028 0.0081 0.0081
Leishmania major cathepsin L-like protease 0.0009 0.001 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0009 0.001 0.0014
Onchocerca volvulus 0.0194 0.0711 0.1635
Onchocerca volvulus 0.1138 0.4296 1
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0194 0.0711 0.0711
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0061 0.0206 0.0206
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0193 0.0708 1
Echinococcus granulosus neuropeptide receptor 0.0194 0.0711 0.0711
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Schistosoma mansoni sodium/chloride dependent transporter 0.1138 0.4296 0.4296
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0193 0.0708 0.0708
Echinococcus granulosus alpha 1A adrenergic receptor 0.0194 0.0711 0.0711
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0013 0.0024 0.0024
Echinococcus multilocularis neuropeptides capa receptor 0.0194 0.0711 0.0711
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Brugia malayi hypothetical protein 0.0194 0.0711 0.1654
Loa Loa (eye worm) hypothetical protein 0.0193 0.0708 0.0708
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0009 0.001 0.001
Trypanosoma cruzi cruzipain precursor, putative 0.0009 0.001 0.0014
Schistosoma mansoni histamine h1 receptor 0.0194 0.0711 0.0711
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0057 0.0191 0.2691
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0009 0.001 0.0014
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0193 0.0708 0.0708
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0008 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0464 0.1738 0.1738
Brugia malayi Cathepsin L-like precursor 0.0009 0.001 0.0023
Loa Loa (eye worm) G-protein coupled receptor 0.0194 0.0711 0.0711
Mycobacterium ulcerans glutaminase 0.0208 0.0765 1
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Echinococcus granulosus neuropeptide s receptor 0.0544 0.204 0.204
Brugia malayi hypothetical protein 0.0194 0.0711 0.1654
Echinococcus granulosus G protein coupled receptor 139 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0058 0.0196 0.0196
Echinococcus multilocularis dro:myosuppressin receptor 0.0194 0.0711 0.0711
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0194 0.0711 0.0711
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Schistosoma mansoni neuropeptide F-like receptor 0.0194 0.0711 0.0711
Brugia malayi intermediate filament protein 0.0021 0.0055 0.0129
Brugia malayi Tachykinin-like peptides receptor 99D 0.0194 0.0711 0.1654
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0194 0.0711 0.0711
Brugia malayi Serotonin receptor 0.0656 0.2465 0.5736
Loa Loa (eye worm) hypothetical protein 0.0926 0.3491 0.3491
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0008 0.0005 0.0013
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0051 0.0168 0.0168
Echinococcus multilocularis allatostatin A receptor 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0021 0.0055 0.0055
Brugia malayi Cathepsin L-like precursor 0.0009 0.001 0.0023
Leishmania major cathepsin L-like protease 0.0009 0.001 0.0014
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0193 0.0708 0.0708
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0193 0.0708 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0194 0.0711 0.0711
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1913 0.7241 0.7241
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0397 0.1481 0.1481
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Schistosoma mansoni hypothetical protein 0.0051 0.0168 0.0168
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0194 0.0711 0.0711
Echinococcus granulosus rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0035 0.0107 0.2528
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.0014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0035 0.0107 0.126
Echinococcus granulosus lamin dm0 0.0021 0.0055 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0193 0.0708 0.0708
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0035 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Plasmodium vivax SET domain protein, putative 0.0057 0.0191 0.2587
Brugia malayi Serotonin receptor 0.0194 0.0711 0.1654
Loa Loa (eye worm) hypothetical protein 0.0237 0.0876 0.0876
Schistosoma mansoni hypothetical protein 0.0061 0.0206 0.0206
Trypanosoma cruzi cysteine peptidase, putative 0.0009 0.001 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0734 0.2764 0.2764
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0009 0.001 0.001
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0038 0.0119 0.0277
Echinococcus multilocularis sodium and chloride dependent glycine 0.0193 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Echinococcus multilocularis G protein coupled receptor 139 0.0194 0.0711 0.0711
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0194 0.0711 0.0711
Leishmania major cysteine peptidase A (CPA) 0.0009 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0009 0.001 0.0014
Echinococcus multilocularis lamin dm0 0.0021 0.0055 0.0055
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0028 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0191 0.0191
Loa Loa (eye worm) intermediate filament protein 0.0021 0.0055 0.0055
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0194 0.0711 0.0711
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0057 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0109 0.0387 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0193 0.0708 0.0708
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Echinococcus granulosus cathepsin l1 0.0009 0.001 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0194 0.0711 0.0711
Onchocerca volvulus 0.0193 0.0708 0.1629
Loa Loa (eye worm) hypothetical protein 0.0024 0.0067 0.0067
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.001 0.0012 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0194 0.0711 0.1654
Loa Loa (eye worm) hypothetical protein 0.1138 0.4296 0.4296
Loa Loa (eye worm) glutaminase 0.0208 0.0765 0.0765
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0194 0.0711 0.1635
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0009 0.001 0.014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Schistosoma mansoni amine GPCR 0.0194 0.0711 0.0711
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0193 0.0708 0.1648
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0193 0.0708 0.0708
Echinococcus granulosus neuropeptides capa receptor 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0021 0.0054 0.0054
Echinococcus granulosus hypothetical protein 0.0887 0.3341 0.3341
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0763 0.2873 0.2873
Echinococcus multilocularis rhodopsin orphan GPCR 0.0194 0.0711 0.0711
Onchocerca volvulus 0.0194 0.0711 0.1635
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0194 0.0711 0.0711
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0194 0.0711 0.0711
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0222 0.0819 0.4828
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Trypanosoma cruzi cysteine peptidase, putative 0.0009 0.001 0.0014
Loa Loa (eye worm) neuropeptide F receptor 0.0194 0.0711 0.0711
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0194 0.0711 0.0711
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Brugia malayi neuropeptide F receptor 0.0194 0.0711 0.1654
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0222 0.0819 0.4828
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0021 0.0055 0.0055
Schistosoma mansoni biogenic amine (5HT) receptor 0.1287 0.4863 0.4863
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0193 0.0708 0.0708
Brugia malayi cytoplasmic intermediate filament protein 0.0011 0.0018 0.0041
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0194 0.0711 0.0711
Brugia malayi G protein-coupled receptor F59B2.13 0.0194 0.0711 0.1654
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Brugia malayi larval opioid receptor 0.0194 0.0711 0.1654
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0057 0.0191 0.0191
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0055 0.0183 0.0183
Onchocerca volvulus 0.0194 0.0711 0.1635
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0009 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0222 0.0819 0.4828
Loa Loa (eye worm) hypothetical protein 0.0926 0.3491 0.3491
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Brugia malayi putative neuropeptide receptor 0.0194 0.0711 0.1654
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0009 0.001 0.0014
Echinococcus granulosus serotonin receptor 0.0194 0.0711 0.0711
Echinococcus granulosus neuropeptide FF receptor 2 0.0194 0.0711 0.0711
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Brugia malayi Cytochrome P450 family protein 0.0014 0.0028 0.0065
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0058 0.0196 0.4908
Brugia malayi Papain family cysteine protease containing protein 0.0009 0.001 0.0023
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0015 0.0033 0.0278
Echinococcus granulosus neuropeptides capa receptor 0.0194 0.0711 0.0711
Echinococcus granulosus microtubule associated protein 2 0.0944 0.3559 0.3559
Schistosoma mansoni hypothetical protein 0.0369 0.1375 0.1375
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0009 0.001 0.001
Echinococcus multilocularis cathepsin L cysteine protease 0.0009 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.1138 0.4296 0.4296
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0009 0.001 0.0014
Echinococcus granulosus neuropeptide Y receptor 0.0194 0.0711 0.0711
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0194 0.0711 0.0711
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0464 0.1738 1
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0005 0.0005
Leishmania major C-8 sterol isomerase-like protein 0.0464 0.1738 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0194 0.0711 0.0711
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0035 0.0107 0.126
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Leishmania major cathepsin L-like protease 0.0009 0.001 0.0014
Onchocerca volvulus 0.0451 0.1689 0.3917
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0193 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0191 0.0191
Schistosoma mansoni lamin 0.0021 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Brugia malayi ORL1-like opioid receptor 0.0194 0.0711 0.1654
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Plasmodium falciparum amino acid transporter, putative 0.0193 0.0708 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0013
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1138 0.4296 1
Brugia malayi glutaminase DH11.1 0.0208 0.0765 0.178
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0194 0.0711 0.0711
Schistosoma mansoni opsin-like receptor 0.0194 0.0711 0.0711
Leishmania major cathepsin L-like protease 0.0009 0.001 0.0014
Echinococcus multilocularis neuropeptides capa receptor 0.0194 0.0711 0.0711
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Onchocerca volvulus 0.0194 0.0711 0.1635
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0194 0.0711 0.0711
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0222 0.0819 0.4828
Toxoplasma gondii hypothetical protein 0.0193 0.0708 1
Echinococcus granulosus g protein coupled receptor 0.0194 0.0711 0.0711
Schistosoma mansoni hypothetical protein 0.0194 0.0711 0.0711
Schistosoma mansoni hypothetical protein 0.0194 0.0711 0.0711
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0194 0.0711 0.0711
Loa Loa (eye worm) glutaminase 2 0.0208 0.0765 0.0765
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0194 0.0711 0.1654
Echinococcus granulosus neuropeptide receptor A26 0.0544 0.204 0.204
Schistosoma mansoni biogenic amine receptor 0.0194 0.0711 0.0711
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0009 0.001 0.0014
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0074 0.0396
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0508 0.1905 0.1905
Echinococcus multilocularis neuropeptide receptor 0.0194 0.0711 0.0711
Brugia malayi Pre-SET motif family protein 0.0397 0.1481 0.3447
Trypanosoma brucei cytochrome P450, putative 0.0014 0.0028 0.0119
Echinococcus multilocularis neuropeptide FF receptor 2 0.0194 0.0711 0.0711
Schistosoma mansoni hypothetical protein 0.0194 0.0711 0.0711
Loa Loa (eye worm) cysteine protease 0.0009 0.001 0.001
Schistosoma mansoni biogenic amine (5HT) receptor 0.264 1 1
Plasmodium vivax amine transporter, putative 0.0193 0.0708 1
Brugia malayi Cathepsin L-like precursor 0.0009 0.001 0.0023
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0035 0.0107 0.0107
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0061 0.0206 0.0206
Loa Loa (eye worm) CYP4Cod1 0.0014 0.0028 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0194 0.0711 0.0711
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0763 0.2873 0.2873
Brugia malayi hypothetical protein 0.0395 0.1475 0.3433
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0026
Loa Loa (eye worm) TYRA-2 protein 0.0194 0.0711 0.0711

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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