Detailed information for compound 562260

Basic information

Technical information
  • TDR Targets ID: 562260
  • Name: allyl 2-methylprop-2-enoate; methyl 2-methylp rop-2-enoate; 1-vinylpyrrolidin-2-one
  • MW: 337.411 | Formula: C18H27NO5
  • H donors: 0 H acceptors: 3 LogP: 3.08 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)C(=C)C.C=CN1CCCC1=O.C=CCOC(=O)C(=C)C
  • InChi: 1S/C7H10O2.C6H9NO.C5H8O2/c1-4-5-9-7(8)6(2)3;1-2-7-5-3-4-6(7)8;1-4(2)5(6)7-3/h4H,1-2,5H2,3H3;2H,1,3-5H2;1H2,2-3H3
  • InChiKey: HVYQZCLEPABLCN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-methyl-2-propenoic acid allyl ester; 2-methyl-2-propenoic acid methyl ester; 1-vinyl-2-pyrrolidinone
  • 1-ethenylpyrrolidin-2-one; methyl 2-methylprop-2-enoate; prop-2-enyl 2-methylprop-2-enoate
  • 2-methylacrylic acid allyl ester; 2-methylacrylic acid methyl ester; 1-vinyl-2-pyrrolidone
  • Duragel 75
  • 2-methylprop-2-enoic acid allyl ester; 2-methylprop-2-enoic acid methyl ester; 1-vinyl-2-pyrrolidinone
  • 38809-73-3
  • 2-Propenoic acid, 2-methyl-, endo-
  • 2-Pyrrolidinone, 1-ethenyl-, polymer with methyl 2-methyl-2-propenoate and 2-propenyl 2-methyl-2-propenoate
  • Permaflex Naturals
  • Surfilcon A
  • Surfilcon A [USAN]
  • 1-Vinyl-2-pyrrolidinone polymer with methyl methacrylate and allyl methacrylate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Mycobacterium leprae Probable lipase LipE 0.0035 0.0077 0.3032
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0077 0.0238
Brugia malayi Pax transcription activation domain interacting protein 0.002 0.002 0.0098
Echinococcus granulosus lamin 0.0027 0.0045 0.0038
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0586 0.209 0.2085
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0025 0.004
Plasmodium vivax diacylglycerol kinase, putative 0.0029 0.0054 0.2313
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0209 1
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0166 0.0159
Mycobacterium ulcerans transmembrane cation transporter 0.0035 0.0077 0.0213
Brugia malayi hypothetical protein 0.0029 0.0054 0.0261
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0025 0.004
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.0025 0.0218
Echinococcus granulosus twik family of potassium channels 0.0035 0.0077 0.007
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.008 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0284 0.0277
Brugia malayi Pre-SET motif family protein 0.006 0.0168 0.0802
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0025 0.0015
Schistosoma mansoni calcium-activated potassium channel 0.0035 0.0077 0.007
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0586 0.209 0.2085
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.008 1
Onchocerca volvulus 0.0035 0.0077 0.0342
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0284 0.1061
Trichomonas vaginalis bmru protein, putative 0.0029 0.0054 0.0204
Loa Loa (eye worm) hypothetical protein 0.002 0.002 0.0076
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0167 0.0557 0.055
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0077 0.0342
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0029 0.0054 0.0047
Onchocerca volvulus 0.0035 0.0077 0.0339
Loa Loa (eye worm) hypothetical protein 0.0586 0.209 0.78
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0289
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0166 0.0549
Onchocerca volvulus 0.0021 0.0025 0.0025
Brugia malayi Diacylglycerol kinase protein 2 0.0029 0.0054 0.0261
Plasmodium vivax potassium channel, putative 0.0035 0.0077 0.3845
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0077 0.3877
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0025 0.0015
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0025 0.0279
Schistosoma mansoni hypothetical protein 0.0167 0.0557 0.055
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0045 0.0168
Schistosoma mansoni diacylglycerol kinase theta 0.0029 0.0054 0.0047
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0025 0.0117
Brugia malayi Ceramide kinase 0.0029 0.0054 0.0261
Loa Loa (eye worm) hypothetical protein 0.0051 0.0135 0.0505
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0132 0.0443
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0025 0.0015
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0077 0.0342
Schistosoma mansoni twik family of potassium channels-related 0.0035 0.0077 0.007
Mycobacterium ulcerans hypothetical protein 0.0035 0.0077 0.0214
Echinococcus granulosus tumor protein p63 0.0669 0.2391 0.2386
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.002 0.002 0.0098
Trypanosoma cruzi ion transport protein, putative 0.0035 0.0077 0.9462
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0025 0.004
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0066 0.0197
Echinococcus granulosus sphingosine kinase 1 0.0748 0.268 0.2674
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Trichomonas vaginalis diacylglycerol kinase, putative 0.0029 0.0054 0.0204
Onchocerca volvulus 0.0029 0.0054 0.0204
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0203
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.0027
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0025 0.0015
Loa Loa (eye worm) hypothetical protein 0.002 0.002 0.0076
Plasmodium falciparum potassium channel 0.0035 0.0077 0.4626
Giardia lamblia Hypothetical protein 0.0035 0.0077 1
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0035 0.0077 0.0368
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0025 0.0015
Schistosoma mansoni sphingosine kinase A B 0.0748 0.268 0.2674
Trichomonas vaginalis diacylglycerol kinase, putative 0.0029 0.0054 0.0204
Plasmodium falciparum diacylglycerol kinase, putative 0.0029 0.0054 0.2782
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0035 0.0077 0.0368
Echinococcus granulosus intermediate filament protein 0.0027 0.0045 0.0038
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.0154 0.7049
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0025 0.0015
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0071 0.0209 0.073
Mycobacterium tuberculosis Conserved protein 0.0035 0.0077 0.0238
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Brugia malayi hypothetical protein 0.002 0.002 0.0098
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0045 0.0168
Onchocerca volvulus 0.0035 0.0077 0.0339
Plasmodium vivax SET domain protein, putative 0.006 0.0168 1
Onchocerca volvulus 0.0035 0.0077 0.0342
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.002 0.0000012245
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0025 0.0015
Entamoeba histolytica diacylglycerol kinase, putative 0.0029 0.0054 0.0128
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0035 0.0077 0.0368
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0035 0.0077 0.0213
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0025 0.0025
Entamoeba histolytica diacylglycerol kinase, putative 0.0029 0.0054 0.0128
Brugia malayi intermediate filament protein 0.0027 0.0045 0.0215
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0035 0.0077 0.0368
Onchocerca volvulus 0.0027 0.0045 0.0147
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0025 0.0092
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.0154 0.0147
Loa Loa (eye worm) TWK-28 protein 0.0035 0.0077 0.0287
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0029 0.0054 0.2313
Onchocerca volvulus 0.0035 0.0077 0.0339
Loa Loa (eye worm) TWK-7 protein 0.0035 0.0077 0.0287
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0025 0.0279
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0025 0.0015
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0035 0.0077 0.007
Brugia malayi Eye-specific diacylglycerol kinase 0.0029 0.0054 0.0261
Schistosoma mansoni twik family of potassium channels-related 0.0035 0.0077 0.007
Plasmodium falciparum diacylglycerol kinase, putative 0.0029 0.0054 0.2782
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0025 0.0218
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.004 0.1309
Onchocerca volvulus Ceramide kinase 1 homolog 0.0029 0.0054 0.0204
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Schistosoma mansoni topbp1 0.002 0.002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0289
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0159 0.0152
Brugia malayi diacylglycerol kinase 0.0029 0.0054 0.0261
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.004 0.1575
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.008 1
Echinococcus multilocularis tumor protein p63 0.0669 0.2391 0.2386
Schistosoma mansoni hypothetical protein 0.0035 0.0077 0.007
Loa Loa (eye worm) hypothetical protein 0.0071 0.0209 0.0778
Toxoplasma gondii ion channel protein 0.0035 0.0077 0.3845
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0025 0.0687
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.008 0.0073
Onchocerca volvulus 0.0027 0.0045 0.0147
Brugia malayi beta-lactamase family protein 0.0035 0.0077 0.0371
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0025 0.004
Schistosoma mansoni microtubule-associated protein tau 0.2752 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0077 0.9541
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0284 0.0277
Echinococcus multilocularis twik family of potassium channels 0.0035 0.0077 0.007
Schistosoma mansoni twik family of potassium channels-related 0.0035 0.0077 0.007
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0077 0.0238
Entamoeba histolytica acyl-coA synthetase, putative 0.0071 0.0209 0.0707
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.002 0.0000012245
Plasmodium falciparum potassium channel 0.0035 0.0077 0.4626
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.008 0.0225
Onchocerca volvulus 0.0021 0.0025 0.0025
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0029 0.0054 0.5691
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0054 0.5691
Loa Loa (eye worm) hypothetical protein 0.0027 0.0045 0.0168
Leishmania major hypothetical protein, conserved 0.0029 0.0054 0.1626
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0025 0.004
Mycobacterium ulcerans diacylglycerol kinase 0.0029 0.0054 0.0128
Loa Loa (eye worm) hypothetical protein 0.002 0.002 0.0076
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0035 0.0077 0.0368
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0209 1
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0025 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0077 0.9462
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0168 0.016
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0154 0.0503
Loa Loa (eye worm) hypothetical protein 0.0071 0.0209 0.0778
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0077 0.0371
Loa Loa (eye worm) hypothetical protein 0.002 0.002 0.0076
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0533
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0035 0.0077 0.9462
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Leishmania major hypothetical protein, conserved 0.0025 0.004 0.0824
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0167 0.0557 0.055
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0029 0.0054 0.0204
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.0209 0.073
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0035 0.0077 0.0368
Entamoeba histolytica diacylglycerol kinase, putative 0.0029 0.0054 0.0128
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0092
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0035 0.0077 0.0368
Trypanosoma cruzi diacylglycerol kinase, putative 0.0029 0.0054 0.5691
Onchocerca volvulus 0.0035 0.0077 0.0339
Trichomonas vaginalis set domain proteins, putative 0.0477 0.169 1
Trichomonas vaginalis bmru protein, putative 0.0029 0.0054 0.0204
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0166 0.0549
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0029 0.0054 0.0203
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0077 0.9541
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0209 1
Schistosoma mansoni lamin 0.0027 0.0045 0.0038
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0025 0.004
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.0775 0.2854
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0154 0.0147
Schistosoma mansoni cellular tumor antigen P53 0.0098 0.0306 0.0299
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0077 0.0342
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0007 0.0035
Brugia malayi hypothetical protein 0.0025 0.004 0.019
Trypanosoma cruzi diacylglycerol kinase, putative 0.0029 0.0054 0.5691
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0077 0.0342
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0533
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.008 0.0073
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0071 0.0209 0.0707
Brugia malayi Inositol-1 0.0036 0.008 0.0384
Entamoeba histolytica hypothetical protein, conserved 0.0748 0.268 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.004 0.0148
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.002 0.002 0.00000076858
Echinococcus granulosus calcium activated potassium channel variant 0.0035 0.0077 0.007
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Leishmania major hypothetical protein, conserved 0.0029 0.0054 0.1626
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Echinococcus multilocularis potassium channel subfamily K 8 0.0035 0.0077 0.007
Trichomonas vaginalis replication factor C large subunit, putative 0.002 0.002 0.0000012245
Schistosoma mansoni twik family of potassium channels-related 0.0586 0.209 0.2085
Loa Loa (eye worm) hypothetical protein 0.0026 0.0043 0.0161
Loa Loa (eye worm) diacylglycerol kinase 2 0.0029 0.0054 0.0203
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0035 0.0077 0.9462
Onchocerca volvulus 0.006 0.0168 0.0881
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0168 0.016
Brugia malayi diacylglycerol kinase 0.0029 0.0054 0.0261
Loa Loa (eye worm) hypothetical protein 0.0167 0.0557 0.2078
Leishmania major diacylglycerol kinase, putative 0.0029 0.0054 0.1626
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0533
Schistosoma mansoni twik family of potassium channels-related 0.0035 0.0077 0.007
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0029 0.0054 0.5691
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0035 0.0077 0.0287
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0035 0.0077 0.007
Onchocerca volvulus 0.0098 0.0306 0.1709
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.008 0.0225
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0143 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.0154 0.0526
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0284 0.0277
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0154 0.0738
Loa Loa (eye worm) hypothetical protein 0.0098 0.0306 0.1141
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0166 0.0159
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0586 0.209 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Loa Loa (eye worm) apoptosis regulator protein 0.0167 0.0557 0.2078
Schistosoma mansoni twik family of potassium channels-related 0.0035 0.0077 0.007
Trypanosoma brucei calcium-activated potassium channel, putative 0.0035 0.0077 0.9462
Echinococcus granulosus Diacylglycerol kinase zeta 0.0029 0.0054 0.0047
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0025 0.0336
Schistosoma mansoni DNA ligase IV 0.002 0.002 0.0013
Mycobacterium ulcerans lipase LipD 0.0035 0.0077 0.0214
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0077 0.0238
Leishmania major ion transport protein-like protein 0.0035 0.0077 0.2851
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0025 0.004
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0035 0.0077 0.0368
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0143 0.0483
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0025 0.0279
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0132 0.0443
Mycobacterium ulcerans ion transport protein 0.0035 0.0077 0.0213
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0035 0.0077 0.9462
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0077 0.0238
Echinococcus multilocularis lamin dm0 0.0027 0.0045 0.0038
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0166 0.7704
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0054 0.5691
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0168 0.016
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0289
Leishmania major diacylglycerol kinase-like protein 0.0029 0.0054 0.1626
Schistosoma mansoni sphingoid long chain base kinase 0.0748 0.268 0.2674
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0025 0.004
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0166 0.0159
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0203
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0077 0.0289
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0209 0.0707
Brugia malayi DKFZp564C0469 protein 0.002 0.002 0.0098
Mycobacterium ulcerans hypothetical protein 0.0071 0.0209 0.0707
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0284 0.136
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.0284
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.004 0.3222
Loa Loa (eye worm) hypothetical protein 0.006 0.0168 0.0625
Brugia malayi hypothetical protein 0.0035 0.0077 0.0368
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0077 0.0339
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0289
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0132 0.0443
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0035 0.0077 0.0368
Leishmania major potassium channel subunit-like protein 0.0035 0.0077 0.2851
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0025 0.0015
Loa Loa (eye worm) beta-lactamase 0.0035 0.0077 0.0289
Loa Loa (eye worm) hypothetical protein 0.002 0.002 0.0076
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0209 0.0998
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0077 0.007
Leishmania major sphingosine kinase A, B, putative 0.0029 0.0054 0.1626
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0077 0.9462
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0054 0.0204
Loa Loa (eye worm) uncoordinated protein 58 0.0035 0.0077 0.0287
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0045 0.0215
Echinococcus multilocularis lamin 0.0027 0.0045 0.0038
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0209 1
Brugia malayi hypothetical protein 0.0016 0.0007 0.0035
Entamoeba histolytica diacylglycerol kinase, putative 0.0029 0.0054 0.0128
Mycobacterium ulcerans hypothetical protein 0.0748 0.268 1
Leishmania major hypothetical protein, conserved 0.0035 0.0077 0.2876
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0025 0.0025
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0025 0.0687
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0035 0.0077 0.9462
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0035 0.0077 0.0237
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0154 0.0147
Schistosoma mansoni hypothetical protein 0.0035 0.0077 0.007
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0035 0.0077 0.0287
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0143 1
Echinococcus multilocularis ceramide kinase 0.0029 0.0054 0.0047
Treponema pallidum DNA ligase (lig) 0.002 0.002 0.5
Onchocerca volvulus 0.0035 0.0077 0.0342
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0025 0.0117
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0076 0.0364
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0029 0.0054 0.5691
Echinococcus granulosus small conductance calcium activated potassium 0.0035 0.0077 0.007
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.008 0.0358
Brugia malayi hypothetical protein 0.002 0.002 0.0098
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0077 0.0339
Brugia malayi follicle stimulating hormone receptor 0.0241 0.0827 0.3956
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0025 0.0687
Toxoplasma gondii ABC1 family protein 0.0035 0.0077 0.3877
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0077 0.007
Schistosoma mansoni hypothetical protein 0.0167 0.0557 0.055
Schistosoma mansoni hypothetical protein 0.0167 0.0557 0.055
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Echinococcus multilocularis Diacylglycerol kinase theta 0.0029 0.0054 0.0047
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0168 0.016
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0029 0.0054 0.2313
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0289
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0167 0.0557 0.055
Echinococcus multilocularis calcium activated potassium channel variant 0.0035 0.0077 0.007
Schistosoma mansoni apoptosis regulator bax 0.0167 0.0557 0.055
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0025 0.0017
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.0047
Echinococcus multilocularis nibrin 0.002 0.002 0.0013
Echinococcus granulosus nibrin 0.002 0.002 0.0013
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0025 0.0015
Onchocerca volvulus 0.0035 0.0077 0.0339
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Schistosoma mansoni diacylglycerol kinase theta 0.0029 0.0054 0.0047
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0025 0.0015
Loa Loa (eye worm) ceramide kinase 0.0029 0.0054 0.0203
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0029 0.0054 0.0047
Echinococcus multilocularis sphingosine kinase 1 0.0748 0.268 0.2674
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0166 0.0572
Onchocerca volvulus 0.0035 0.0077 0.0339
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0025 0.0687
Echinococcus granulosus potassium channel subfamily K 8 0.0035 0.0077 0.007
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0035 0.0077 0.0368
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0209 0.0998
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0209 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0143 0.8312
Echinococcus multilocularis small conductance calcium activated potassium 0.0035 0.0077 0.007
Schistosoma mansoni chromosome transmission fidelity factor 0.002 0.002 0.0013
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0077 0.0238
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0025 0.0117
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0284 0.0277
Mycobacterium ulcerans beta-lactamase 0.0035 0.0077 0.0214
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0284 0.0277
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0077 0.007
Echinococcus multilocularis potassium channel subfamily K 0.0035 0.0077 0.007
Brugia malayi Pre-SET motif family protein 0.0419 0.1478 0.7072
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Echinococcus multilocularis twik family of potassium channels 0.0035 0.0077 0.007
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0066 0.2441
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0209 0.0707
Echinococcus granulosus potassium channel subfamily K 0.0035 0.0077 0.007
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0168 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0166 0.0549
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0167 0.0557 0.055
Schistosoma mansoni inositol monophosphatase 0.0036 0.008 0.0073
Trypanosoma cruzi Sphingosine kinase 0.0029 0.0054 0.5691
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0154 0.0503
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0029 0.0054 0.5691
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0166 0.9917
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.0025 0.0218
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0029 0.0054 0.0204
Leishmania major calcium/potassium channel (CAKC), putative 0.0035 0.0077 0.2851
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0135 0.0648
Loa Loa (eye worm) hypothetical protein 0.0021 0.0025 0.0092
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0135 0.0505
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0035 0.0077 0.0368
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Brugia malayi hypothetical protein 0.0035 0.0077 0.0368
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0025 0.0015
Loa Loa (eye worm) oxidoreductase 0.0021 0.0025 0.0092
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0025 0.0015
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0025 0.004
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0029 0.0054 0.0047
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0077 0.0339
Leishmania major hypothetical protein, conserved 0.0035 0.0077 0.2851
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0025 0.0092
Mycobacterium tuberculosis Conserved protein 0.0035 0.0077 0.0238
Trichomonas vaginalis esterase, putative 0.0035 0.0077 0.0342
Toxoplasma gondii ion channel protein 0.0035 0.0077 0.3845
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0025 0.004
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.014 0.0524
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0035 0.0077 0.0287
Mycobacterium tuberculosis Diacylglycerol kinase 0.0029 0.0054 0.0152
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0029 0.0054 0.0047
Trypanosoma cruzi Sphingosine kinase 0.0029 0.0054 0.5691
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0166 0.0159
Onchocerca volvulus 0.0025 0.0038 0.0108
Trypanosoma brucei Sphingosine kinase 0.0029 0.0054 0.5691
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0209 0.0707
Schistosoma mansoni intermediate filament proteins 0.0027 0.0045 0.0038
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.004 0.1309
Schistosoma mansoni calcium-activated potassium channel 0.0035 0.0077 0.007
Plasmodium vivax diacylglycerol kinase, putative 0.0029 0.0054 0.2313
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1632 0.591 0.5907
Schistosoma mansoni lamin 0.0027 0.0045 0.0038
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0029 0.0054 0.0047
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0025 0.0117
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.004 0.3222
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0025 0.0015
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0077 0.3032
Onchocerca volvulus 0.0021 0.0025 0.0025
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0071 0.0209 0.0707
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0132 0.0443
Trypanosoma cruzi ion transport protein, putative 0.0035 0.0077 0.9462
Mycobacterium tuberculosis Conserved protein 0.0748 0.268 1
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0025 0.0687
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0077 0.0238
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0167 0.0557 0.2664
Leishmania major hypothetical protein, conserved 0.0035 0.0077 0.2851
Echinococcus granulosus potassium channel subfamily K 8 0.0035 0.0077 0.007
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0289
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0035 0.0077 0.0368
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0203
Schistosoma mansoni topbp1 0.002 0.002 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0025 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0209 0.0707
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0025 0.0117
Mycobacterium tuberculosis Conserved protein 0.0035 0.0077 0.0238
Echinococcus granulosus twik family of potassium channels 0.0035 0.0077 0.007
Echinococcus multilocularis musashi 0.0027 0.0045 0.0038
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0007 0.0027
Onchocerca volvulus 0.0035 0.0077 0.0339
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0077 0.9541
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0168 0.016
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0209 0.0707
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0035 0.0077 0.0368
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.008 0.0358
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0284 0.0277
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0209 0.0998
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0077 0.0339
Echinococcus multilocularis potassium channel subfamily K 8 0.0035 0.0077 0.007
Schistosoma mansoni inositol monophosphatase 0.0036 0.008 0.0073
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0077 0.0339
Loa Loa (eye worm) hypothetical protein 0.0748 0.268 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.008 0.0358
Echinococcus granulosus ceramide kinase 0.0029 0.0054 0.0047
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0025 0.0017
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0007 0.0035
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.004 0.1575
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0419 0.1478 0.5516
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0284 0.0277
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.008 0.4064
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0143 0.046
Schistosoma mansoni twik family of potassium channels-related 0.0035 0.0077 0.007
Brugia malayi beta-lactamase family protein 0.0035 0.0077 0.0371
Trichomonas vaginalis sphingosine kinase, putative 0.0029 0.0054 0.0204
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0025 0.0015
Echinococcus granulosus replication factor c subunit 1 0.002 0.002 0.0013
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0025 0.0687
Brugia malayi beta-lactamase 0.0035 0.0077 0.0371
Plasmodium vivax potassium channel, putative 0.0035 0.0077 0.3845
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Echinococcus granulosus Diacylglycerol kinase theta 0.0029 0.0054 0.0047
Loa Loa (eye worm) hypothetical protein 0.0551 0.1961 0.7319
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0029 0.0054 0.0204
Onchocerca volvulus 0.0035 0.0077 0.0339
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0035 0.0077 0.0368
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0077 0.007
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0025 0.0015
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0077 0.0238
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0035 0.0077 0.0368
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0533
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.008 0.3025
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0077 0.0214
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0168 0.016
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0077 0.0214
Onchocerca volvulus 0.0477 0.169 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0168 0.016
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0135 0.0648
Loa Loa (eye worm) hypothetical protein 0.0071 0.0209 0.0778
Schistosoma mansoni twik family of potassium channels-related 0.0035 0.0077 0.007
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0035 0.0077 0.0368
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0209 0.0707
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.004 0.3222
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0241 0.0827 0.3086
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0077 0.0342
Echinococcus multilocularis replication factor c subunit 1 0.002 0.002 0.0013
Brugia malayi topoisomerase 0.002 0.002 0.0098
Onchocerca volvulus 0.0071 0.0209 0.1127
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0071 0.0209 0.0707
Trichomonas vaginalis sphingosine kinase, putative 0.0029 0.0054 0.0204
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0167 0.0557 0.055
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Loa Loa (eye worm) hypothetical protein 0.0586 0.209 0.78
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.008 1
Trypanosoma brucei diacylglycerol kinase, putative 0.0029 0.0054 0.5691
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0025 0.0017
Echinococcus granulosus lamin dm0 0.0027 0.0045 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0025 0.0117
Loa Loa (eye worm) hypothetical protein 0.002 0.002 0.0076
Loa Loa (eye worm) inositol-1 0.0036 0.008 0.0299
Schistosoma mansoni hypothetical protein 0.0035 0.0076 0.0069
Toxoplasma gondii diacylglycerol kinase, putative 0.0029 0.0054 0.2313
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.0533
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Schistosoma mansoni calcium-activated potassium channel 0.0035 0.0077 0.007
Echinococcus multilocularis microtubule associated protein 2 0.2752 1 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0287
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0025 0.004
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0035 0.0077 0.9462
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0025 0.0279

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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