Detailed information for compound 571188

Basic information

Technical information
  • TDR Targets ID: 571188
  • Name: calcium (2S)-2-hydroxy-3-phenyl-propanoate
  • MW: 372.426 | Formula: C18H20CaO6
  • H donors: 2 H acceptors: 6 LogP: 3.55 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@H](C(=O)[O-])Cc1ccccc1.O[C@H](C(=O)[O-])Cc1ccccc1.[CaH2+2]
  • InChi: 1S/2C9H10O3.Ca/c2*10-8(9(11)12)6-7-4-2-1-3-5-7;/h2*1-5,8,10H,6H2,(H,11,12);/q;;+2/p-2/t2*8-;/m00./s1
  • InChiKey: OLPHGSKFJSNPOA-QXGOIDDHSA-L  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • calcium (2S)-2-hydroxy-3-phenylpropanoate
  • calcium (2S)-2-hydroxy-3-phenyl-propionate
  • 57618-26-5
  • Calcium bis((S)-3-phenyllactate)
  • EINECS 260-854-7

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0311 0.0254
Loa Loa (eye worm) hypothetical protein 0.0194 0.4047 0.4098
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0807 0.1974
Loa Loa (eye worm) runx1 0.0056 0.0938 0.0899
Brugia malayi MAP kinase sur-1 0.005 0.0807 0.0795
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0221 0.4655 0.8914
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0273 0.5838 0.5954
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.103 0.1406
Schistosoma mansoni hypothetical protein 0.0291 0.6232 0.8509
Schistosoma mansoni bromodomain containing protein 0.0064 0.1119 0.1528
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0064 0.0014
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.1229 0.1678
Plasmodium falciparum glutathione reductase 0.0034 0.0426 0.191
Brugia malayi Thioredoxin reductase 0.0097 0.1855 0.1869
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0426 0.6981
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.2008 0.2741
Echinococcus granulosus cpg binding protein 0.0032 0.039 0.0342
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0426 0.103
Entamoeba histolytica CAAX amino terminal protease family 0.004 0.0572 0.1221
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0807 0.0761
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0426 0.103
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0089 0.0058
Plasmodium falciparum thioredoxin reductase 0.0097 0.1855 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.005 0.0068
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0104 0.2008 0.1968
Loa Loa (eye worm) hypothetical protein 0.004 0.0579 0.053
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0426 0.103
Schistosoma mansoni cpg binding protein 0.0032 0.039 0.0532
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0426 0.191
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0426 0.191
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0426 0.103
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0807 0.1974
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0807 0.4021
Toxoplasma gondii hypothetical protein 0.004 0.0572 0.285
Schistosoma mansoni ap endonuclease 0.0019 0.0089 0.0122
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0882 0.0871
Schistosoma mansoni hypothetical protein 0.0339 0.7324 1
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0735 0.0688
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0807 0.1815
Echinococcus granulosus CAAX prenyl protease 2 0.0194 0.4047 0.4017
Loa Loa (eye worm) hypothetical protein 0.0044 0.0658 0.0612
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0807 0.0765
Treponema pallidum hypothetical protein 0.004 0.0572 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0221 0.4655 0.8914
Trypanosoma brucei trypanothione reductase 0.0097 0.1855 0.4569
Mycobacterium ulcerans hypothetical protein 0.004 0.0572 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0472 0.0424
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0232 0.081
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.3717 0.631
Onchocerca volvulus 0.0093 0.1773 0.1544
Loa Loa (eye worm) glutathione reductase 0.0097 0.1855 0.1843
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0807 0.1249
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0426 0.191
Trypanosoma brucei protein kinase, putative 0.005 0.0807 0.1974
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.5838 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0089 0.0194
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0426 0.103
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.1039 0.0994
Trypanosoma brucei CAAX amino terminal protease, putative 0.0194 0.4047 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0426 0.6981
Loa Loa (eye worm) hypothetical protein 0.0448 0.9783 1
Brugia malayi CXXC zinc finger family protein 0.0028 0.0311 0.0285
Echinococcus multilocularis Protein lozenge 0.0056 0.0938 0.0892
Loa Loa (eye worm) PHD-finger family protein 0.002 0.013 0.0068
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0937 0.4669
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0426 0.0587
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.5838 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0225 0.0198
Chlamydia trachomatis hypothetical protein 0.004 0.0572 1
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.3717 0.631
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0426 0.103
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0209 0.0286
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0882 0.1204
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0735 0.1003
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0232 0.081
Loa Loa (eye worm) thioredoxin reductase 0.0097 0.1855 0.1843
Loa Loa (eye worm) hypothetical protein 0.0025 0.0232 0.0173
Mycobacterium ulcerans hypothetical protein 0.004 0.0572 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0089 0.0026
Echinococcus multilocularis CAAX prenyl protease 2 0.0194 0.4047 0.4017
Toxoplasma gondii exonuclease III APE 0.0019 0.0089 0.0444
Schistosoma mansoni cpg binding protein 0.0032 0.039 0.0532
Onchocerca volvulus Glucosylceramidase homolog 0.0179 0.3717 0.3596
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0426 0.191
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.3717 0.631
Toxoplasma gondii thioredoxin reductase 0.0097 0.1855 0.9238
Brugia malayi CAAX amino terminal protease family protein 0.0194 0.4047 0.4117
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0426 0.2124
Plasmodium falciparum glutathione reductase 0.0097 0.1855 1
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0735 0.069
Mycobacterium ulcerans integral membrane protein 0.004 0.0572 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.1229 0.1199
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0472 0.0424
Brugia malayi glutathione reductase 0.0097 0.1855 0.1869
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0882 0.0836
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0069 0.1229 0.1982
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0194 0.4047 0.5525
Toxoplasma gondii hypothetical protein 0.004 0.0572 0.285
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0426 0.0404
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0807 0.1974
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0735 0.1003
Echinococcus granulosus thioredoxin glutathione reductase 0.0097 0.1855 0.1814
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0882 0.0836
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0735 0.1003
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0426 0.103
Plasmodium vivax glutathione reductase, putative 0.0097 0.1855 1
Schistosoma mansoni zinc finger protein 0.0015 0.0011 0.0015
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0232 0.081
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.004 0.0572 0.0943
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.3717 0.631
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0097 0.1855 0.3447
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0426 0.103
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.5838 1
Brugia malayi mbt repeat family protein 0.0047 0.0735 0.072
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0807 0.1974
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.3717 0.631
Mycobacterium tuberculosis Probable reductase 0.0221 0.4655 0.8914
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0426 0.2124
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0426 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0882 0.0836
Plasmodium falciparum thioredoxin reductase 0.0034 0.0426 0.191
Toxoplasma gondii CAAX amino terminal protease family protein 0.004 0.0572 0.285
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0807 0.1974
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0089 0.0194
Plasmodium vivax thioredoxin reductase, putative 0.0097 0.1855 1
Loa Loa (eye worm) hypothetical protein 0.01 0.192 0.191
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0089 0.0194
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0209 0.016
Schistosoma mansoni hypothetical protein 0.0015 0.0011 0.0015
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0735 0.0688
Echinococcus granulosus zinc finger protein 0.0021 0.0143 0.0093
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0426 0.0587
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0807 0.1249
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0882 0.0836
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0194 0.4047 1
Echinococcus multilocularis zinc finger protein 0.0021 0.0143 0.0093
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0807 0.1249
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0209 0.016
Leishmania major trypanothione reductase 0.0097 0.1855 0.4569
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0807 0.1974
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0426 0.103
Mycobacterium tuberculosis Probable dehydrogenase 0.0221 0.4655 0.8914
Giardia lamblia Hypothetical protein 0.0194 0.4047 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0426 0.103
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0426 0.0582
Echinococcus multilocularis thioredoxin glutathione reductase 0.0097 0.1855 0.1814
Schistosoma mansoni lozenge 0.0056 0.0938 0.128
Loa Loa (eye worm) hypothetical protein 0.01 0.192 0.191
Schistosoma mansoni zinc finger protein 0.0021 0.0143 0.0195
Entamoeba histolytica CAAX amino terminal protease family 0.004 0.0572 0.1221
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0273 0.5838 0.5941
Brugia malayi hypothetical protein 0.0025 0.0232 0.0205
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0426 0.103
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.3935 0.6689
Onchocerca volvulus 0.01 0.192 0.1699
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.3935 0.6689
Mycobacterium tuberculosis Probable oxidoreductase 0.0246 0.5212 1
Echinococcus granulosus neuropeptide receptor A26 0.0458 1 1
Mycobacterium tuberculosis Probable integral membrane protein 0.004 0.0572 0.0943
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0104 0.2008 0.1968
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0246 0.5212 1
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0735 0.0688
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0194 0.4047 0.5525
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0246 0.5212 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0232 0.0548
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.01 0.192 0.2622
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0194 0.4047 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0225 0.0198
Loa Loa (eye worm) hypothetical protein 0.0448 0.9783 1
Schistosoma mansoni ap endonuclease 0.0019 0.0089 0.0122
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0807 0.0761
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0735 0.0448
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0426 0.0659
Loa Loa (eye worm) hypothetical protein 0.0047 0.0735 0.069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0064 0.0087
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.004 0.0572 0.0943
Brugia malayi Trypsin family protein 0.01 0.192 0.1936
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0807 0.0761
Toxoplasma gondii melibiase subfamily protein 0.0104 0.2008 1
Brugia malayi PHD-finger family protein 0.0026 0.0262 0.0235
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.01 0.192 0.2622
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.2008 0.2741
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0221 0.4655 0.8914
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0426 0.0378
Loa Loa (eye worm) hypothetical protein 0.0038 0.0526 0.0476
Brugia malayi Bromodomain containing protein 0.0038 0.0525 0.0505
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.3717 0.631
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0232 0.0548
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0089 0.0039
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0426 0.103
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0426 0.0378
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.1039 0.0994
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0064 0.0087
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0426 0.0852
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0232 0.1156
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0426 0.103
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0232 0.0548
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0807 0.0761
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0807 0.1249
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0426 1
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.5838 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0572 0.0943
Brugia malayi Melibiase family protein 0.0069 0.1229 0.1227
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0735 0.0688
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.3717 0.631
Trypanosoma cruzi trypanothione reductase, putative 0.0097 0.1855 0.4569
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0089 0.0194
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0221 0.4655 0.8914
Schistosoma mansoni hypothetical protein 0.0339 0.7324 1
Treponema pallidum NADH oxidase 0.0034 0.0426 0.6981
Brugia malayi mbt repeat family protein 0.0047 0.0735 0.072
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0089 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.5838 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0426 0.103
Loa Loa (eye worm) hypothetical protein 0.007 0.1249 0.122
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0194 0.4047 0.6884
Brugia malayi hypothetical protein 0.0448 0.9783 1
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.019 0.3953 0.3923
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.2008 0.2741
Loa Loa (eye worm) MBCTL1 0.0054 0.0882 0.0842
Schistosoma mansoni hypothetical protein 0.002 0.013 0.0177
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0426 0.103
Brugia malayi Bromodomain containing protein 0.0076 0.1381 0.1383
Entamoeba histolytica CAAX prenyl protease family 0.0194 0.4047 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0426 0.103
Plasmodium falciparum protease, putative 0.004 0.0572 0.2736
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.2008 0.2741
Echinococcus granulosus endonuclease exonuclease phosphatase 0.019 0.3953 0.3923
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0194 0.4047 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.1229 0.1678
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0246 0.5212 1
Echinococcus multilocularis neuropeptide receptor A26 0.0458 1 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0426 0.6981
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0104 0.2008 0.1968
Onchocerca volvulus 0.0448 0.9783 1
Schistosoma mansoni cpg binding protein 0.0028 0.0311 0.0424
Echinococcus multilocularis neuropeptide s receptor 0.0458 1 1
Echinococcus granulosus geminin 0.0339 0.7324 0.731
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0807 0.1974
Plasmodium vivax protease, putative 0.004 0.0572 0.2736
Echinococcus multilocularis cpg binding protein 0.0032 0.039 0.0342
Loa Loa (eye worm) hypothetical protein 0.0054 0.0882 0.0842
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.005 0.0068
Echinococcus multilocularis geminin 0.0339 0.7324 0.731
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0064 0.0014
Onchocerca volvulus 0.0047 0.0735 0.0448
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0807 0.1102
Leishmania major hypothetical protein, conserved 0.0025 0.0232 0.0548
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0426 0.103
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.5838 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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