Detailed information for compound 571639

Basic information

Technical information
  • TDR Targets ID: 571639
  • Name: [(1R)-3-allyl-2-methyl-4-oxo-cyclopent-2-en-1 -yl] (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-e nyl)cyclopropanecarboxylate
  • MW: 302.408 | Formula: C19H26O3
  • H donors: 0 H acceptors: 2 LogP: 3.68 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCC1=C(C)[C@@H](CC1=O)OC(=O)[C@H]1[C@@H](C1(C)C)C=C(C)C
  • InChi: 1S/C19H26O3/c1-7-8-13-12(4)16(10-15(13)20)22-18(21)17-14(9-11(2)3)19(17,5)6/h7,9,14,16-17H,1,8,10H2,2-6H3/t14-,16+,17+/m0/s1
  • InChiKey: ZCVAOQKBXKSDMS-USXIJHARSA-N  

Network

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Synonyms

  • (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylic acid [(1R)-3-allyl-2-methyl-4-oxo-1-cyclopent-2-enyl] ester
  • [(1R)-2-methyl-4-oxo-3-prop-2-enyl-cyclopent-2-en-1-yl] (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
  • (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylic acid [(1R)-3-allyl-4-keto-2-methyl-cyclopent-2-en-1-yl] ester
  • [(1R)-2-methyl-4-oxo-3-prop-2-enylcyclopent-2-en-1-yl] (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
  • Allethrin
  • esbiothrin
  • [(1R)-2-methyl-4-oxo-3-prop-2-enyl-1-cyclopent-2-enyl] (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
  • [(1R)-3-allyl-2-methyl-4-oxo-1-cyclopent-2-enyl] (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
  • (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-enyl)-1-cyclopropanecarboxylic acid [(1R)-3-allyl-2-methyl-4-oxo-1-cyclopent-2-enyl] ester
  • (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylic acid [(1R)-3-allyl-4-keto-2-methyl-1-cyclopent-2-enyl] ester
  • (1R)-3-allyl-2-methyl-4-oxocyclopent-2-en-1-yl (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate
  • CHEBI:39121
  • ZINC01849693
  • (-)-trans-(R)-allethrin
  • (1R)-2-methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi AMP-binding enzyme family protein 0.0037 0.001 0.0018
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0011 0.0007
Loa Loa (eye worm) nuclear hormone receptor 0.004 0.0017 0.0012
Schistosoma mansoni tar DNA-binding protein 0.007 0.0076 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0039 0.0174
Brugia malayi AMP-binding enzyme family protein 0.0125 0.0184 0.1093
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0052 0.0039 0.028
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0052 0.0039 0.0174
Loa Loa (eye worm) hypothetical protein 0.0037 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0136 0.0206 0.0247
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0045 0.0026 0.0934
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.008 0.0943
Toxoplasma gondii ATPase, AAA family protein 0.0052 0.0039 0.1621
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Schistosoma mansoni glutaminase 0.0834 0.1584 0.1961
Onchocerca volvulus 0.0136 0.0206 0.1057
Brugia malayi Importin beta-1 subunit 0.0061 0.0057 0.0309
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0085 0.0106 0.061
Brugia malayi hypothetical protein 0.0136 0.0206 0.1226
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0125 0.0184 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0125 0.0184 0.2181
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0015 0.018
Loa Loa (eye worm) hypothetical protein 0.014 0.0214 0.0257
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.001 0.0006
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0125 0.0184 0.1108
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0052 0.0039 0.162
Entamoeba histolytica hypothetical protein 0.0228 0.0387 0.3294
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.008 0.0074
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.008 0.0943
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Brugia malayi Inositol-1 0.0037 0.001 0.0021
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Schistosoma mansoni topbp1 0.0052 0.0039 0.0042
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0028 0.0028
Leishmania major hypothetical protein, conserved 0.0136 0.0206 1
Onchocerca volvulus 0.0136 0.0206 0.1057
Schistosoma mansoni alpha-glucosidase 0.0137 0.0207 0.025
Echinococcus multilocularis Nuclear hormone receptor HR96 0.004 0.0017 0.0011
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0076 0.0428
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0028 0.0028
Brugia malayi Pre-SET motif family protein 0.0857 0.1629 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.004
Onchocerca volvulus 0.0072 0.008 0.0376
Loa Loa (eye worm) hypothetical protein 0.0072 0.008 0.009
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.004 0.0017 0.0014
Brugia malayi nuclear hormone receptor 0.0085 0.0106 0.061
Plasmodium vivax patched family protein, putative 0.0038 0.0012 0.0084
Echinococcus multilocularis potassium channel subfamily K 0.0136 0.0206 0.02
Trypanosoma cruzi ion transport protein, putative 0.0136 0.0206 1
Plasmodium falciparum potassium channel 0.0136 0.0206 1
Schistosoma mansoni nuclear hormone receptor 0.004 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0037 0.001 0.0151
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi TAR-binding protein 0.007 0.0076 0.0428
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0136 0.0206 0.1226
Loa Loa (eye worm) hypothetical protein 0.0072 0.008 0.009
Loa Loa (eye worm) uncoordinated protein 58 0.0136 0.0206 0.0247
Brugia malayi nuclear receptor RXR 0.0045 0.0027 0.012
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Schistosoma mansoni patched 1 0.0266 0.0462 0.0567
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0136 0.0206 0.1226
Echinococcus granulosus nuclear receptor nhr 48 0.004 0.0017 0.0014
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0015 0.005
Trypanosoma brucei calcium-activated potassium channel, putative 0.0136 0.0206 1
Brugia malayi AMP-binding enzyme family protein 0.0125 0.0184 0.1093
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0052 0.0039 0.0174
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.001 0.0151
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0123 0.018 0.8707
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0024
Plasmodium vivax acyl-CoA synthetase, putative 0.0093 0.0122 0.5713
Schistosoma mansoni calcium-activated potassium channel 0.0136 0.0206 0.0249
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0011 0.0006
Onchocerca volvulus Bile acid receptor homolog 0.0085 0.0106 0.0518
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Brugia malayi protein C24B5.3 0.0038 0.0012 0.0029
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0136 0.0206 0.1226
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0085 0.0106 0.061
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0052 0.0039 0.0174
Toxoplasma gondii LsmAD domain-containing protein 0.0077 0.009 0.4149
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0015 0.0408
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0045 0.0027 0.0021
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0028 0.0132
Schistosoma mansoni hypothetical protein 0.0136 0.0206 0.0249
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0085 0.0106 0.0125
Brugia malayi hypothetical protein 0.0052 0.0039 0.0199
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Onchocerca volvulus 0.0092 0.0119 0.0586
Mycobacterium tuberculosis Possible penicillin-binding protein 0.046 0.0845 1
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0011 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0085 0.0106 0.061
Schistosoma mansoni nuclear receptor 0.004 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.015 0.0233 0.0281
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.009 0.4149
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0136 0.0206 0.1226
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0007 0.0002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0085 0.0106 0.0125
Schistosoma mansoni tar DNA-binding protein 0.007 0.0076 0.0088
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0015 0.0261
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0141 0.0215 0.026
Schistosoma mansoni hypothetical protein 0.014 0.0214 0.0259
Echinococcus multilocularis GPCR, family 2 0.0065 0.0066 0.006
Leishmania major GTP-binding protein, putative 0.0045 0.0026 0.0934
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0052 0.0039 0.2009
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0028 0.0023
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.004 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.004
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Echinococcus multilocularis FTZ F1 alpha 0.0085 0.0106 0.01
Loa Loa (eye worm) inositol-1 0.0037 0.001 0.0004
Onchocerca volvulus 0.0038 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0619 0.1159 0.1432
Onchocerca volvulus 0.0136 0.0206 0.1057
Schistosoma mansoni calcium-activated potassium channel 0.4112 0.8051 1
Schistosoma mansoni hypothetical protein 0.0256 0.0443 0.0543
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.0113 0.0133
Echinococcus granulosus Protein patched homolog 1 0.0266 0.0462 0.0567
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0619 0.1159 1
Loa Loa (eye worm) hypothetical protein 0.0125 0.0184 0.022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0085 0.0106 0.0123
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0228 0.0387 0.0473
Loa Loa (eye worm) hypothetical protein 0.1323 0.2548 0.3158
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Schistosoma mansoni hypothetical protein 0.0065 0.0066 0.0074
Echinococcus granulosus twik family of potassium channels 0.0136 0.0206 0.0249
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0035 0.0148
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.001 0.0029
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0024
Schistosoma mansoni inositol monophosphatase 0.0037 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0085 0.0106 0.061
Brugia malayi Pax transcription activation domain interacting protein 0.0052 0.0039 0.0199
Trypanosoma cruzi FHA domain containing protein, putative 0.0052 0.0039 0.162
Schistosoma mansoni tar DNA-binding protein 0.007 0.0076 0.0088
Schistosoma mansoni topbp1 0.0052 0.0039 0.0042
Mycobacterium leprae conserved hypothetical protein 0.0072 0.008 0.4233
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0136 0.0206 0.1226
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.0214 0.1276
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0136 0.0206 1
Leishmania major calcium/potassium channel (CAKC), putative 0.0136 0.0206 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0015 0.0012
Onchocerca volvulus Protein patched homolog 0.0038 0.0012 0.0009
Loa Loa (eye worm) patched family protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0028 0.0023
Brugia malayi Calcitonin receptor-like protein seb-1 0.0205 0.0342 0.2064
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0045 0.0026 0.0114
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0085 0.0106 0.061
Toxoplasma gondii hypothetical protein 0.0038 0.0012 0.0233
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0015 0.0408
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0015 0.0408
Leishmania major hypothetical protein, conserved 0.0077 0.009 0.4149
Echinococcus granulosus microtubule associated protein 2 0.2798 0.5458 0.6777
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Schistosoma mansoni nuclear receptor nhr-48 0.004 0.0017 0.0014
Brugia malayi Steroid receptor seven-up type 2 0.0085 0.0106 0.061
Loa Loa (eye worm) hypothetical protein 0.0042 0.0021 0.0018
Loa Loa (eye worm) hypothetical protein 0.0141 0.0215 0.0259
Brugia malayi Nuclear hormone receptor E75 0.004 0.0017 0.0061
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0125 0.0184 0.1108
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.001 0.0003
Echinococcus multilocularis tar DNA binding protein 0.007 0.0076 0.0071
Echinococcus granulosus replication factor c subunit 1 0.0052 0.0039 0.0042
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0085 0.0106 0.0125
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Brugia malayi Patched related family protein 10 0.0038 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0037 0.001 0.0119
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.001 0.0119
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0015 0.1635
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.008 0.0442
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.001 0.0018
Onchocerca volvulus 0.0136 0.0206 0.1057
Schistosoma mansoni hypothetical protein 0.0256 0.0443 0.0543
Brugia malayi CHE-14 protein 0.0266 0.0462 0.2804
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0136 0.0206 0.0247
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.001 0.0171
Schistosoma mansoni hypothetical protein 0.0228 0.0387 0.0473
Brugia malayi hypothetical protein 0.005 0.0036 0.0177
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0136 0.0206 0.1726
Onchocerca volvulus 0.0038 0.0012 0.0009
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.006 0.0068
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0045 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Trypanosoma cruzi importin beta-1 subunit, putative 0.0049 0.0035 0.1384
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0037 0.001 0.0018
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0123 0.018 0.0175
Onchocerca volvulus 0.0168 0.0269 0.1396
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0037 0.001 0.0119
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0136 0.0206 0.0249
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0052 0.0039 0.0186
Brugia malayi nuclear hormone receptor family member nhr-6 0.004 0.0017 0.0061
Onchocerca volvulus 0.0052 0.0039 0.0158
Entamoeba histolytica hypothetical protein 0.0228 0.0387 0.3294
Brugia malayi glutaminase DH11.1 0.0834 0.1584 0.972
Loa Loa (eye worm) hypothetical protein 0.0037 0.001 0.0004
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0037 0.0011 0.0005
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.001 0.0119
Loa Loa (eye worm) hypothetical protein 0.0125 0.0184 0.022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0112 0.1324
Brugia malayi Patched related family protein 4 0.0038 0.0012 0.0029
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0052 0.0039 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.008 0.0092
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0093 0.0122 1
Trichomonas vaginalis conserved hypothetical protein 0.0266 0.0462 0.2451
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0379 0.0685 0.0844
Schistosoma mansoni DNA ligase IV 0.0052 0.0039 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0085 0.0106 0.061
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0045 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Plasmodium falciparum importin beta, putative 0.0061 0.0057 0.2407
Echinococcus granulosus calcium activated potassium channel variant 0.0136 0.0206 0.0249
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0093 0.0122 0.0711
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.001 0.0151
Onchocerca volvulus 0.0136 0.0206 0.1057
Entamoeba histolytica hypothetical protein 0.0228 0.0387 0.3294
Mycobacterium ulcerans hypothetical protein 0.0072 0.008 0.0442
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Onchocerca volvulus 0.0038 0.0012 0.0009
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.0113 0.0107
Schistosoma mansoni hypothetical protein 0.0065 0.0066 0.0074
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0024
Brugia malayi conserved hypotetical protein 0.004 0.0017 0.0061
Entamoeba histolytica acyl-coA synthetase, putative 0.0125 0.0184 0.1539
Toxoplasma gondii patched family protein 0.0038 0.0012 0.0233
Echinococcus granulosus FTZ F1 alpha 0.0085 0.0106 0.0125
Loa Loa (eye worm) hypothetical protein 0.0072 0.008 0.009
Plasmodium vivax ataxin-2 like protein, putative 0.0077 0.009 0.406
Echinococcus granulosus importin subunit beta 1 0.0061 0.0057 0.0064
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0037 0.001 0.0151
Loa Loa (eye worm) hypothetical protein 0.1398 0.2697 0.3344
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Echinococcus granulosus potassium channel subfamily K 8 0.0136 0.0206 0.0249
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.009 0.406
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0085 0.0106 0.061
Loa Loa (eye worm) hypothetical protein 0.0044 0.0025 0.0023
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0076 0.0086
Schistosoma mansoni calcium-activated potassium channel 0.0136 0.0206 0.0249
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0085 0.0106 0.0123
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.001 0.0119
Plasmodium falciparum replication factor C subunit 1, putative 0.0052 0.0039 0.1492
Brugia malayi Bromodomain containing protein 0.004 0.0016 0.0057
Echinococcus multilocularis nibrin 0.0052 0.0039 0.0034
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0136 0.0206 0.1226
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0015 0.007
Brugia malayi hypothetical protein 0.0045 0.0027 0.012
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.004 0.0017 0.0061
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0015 0.0044
Plasmodium falciparum potassium channel 0.0136 0.0206 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0857 0.1629 0.2016
Echinococcus granulosus Nuclear hormone receptor HR96 0.004 0.0017 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.018 0.0217
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.0011 0.0207
Schistosoma mansoni ap endonuclease 0.0039 0.0015 0.0012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0085 0.0106 0.0125
Schistosoma mansoni nuclear receptor 0.004 0.0017 0.0014
Schistosoma mansoni thyroid hormone receptor 0.0464 0.0853 0.1053
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.009 0.406
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi beta-lactamase family protein 0.0072 0.008 0.0448
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0085 0.0106 0.061
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0037 0.0011 0.0007
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0136 0.0206 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0171 0.0206
Trypanosoma brucei PAB1-binding protein , putative 0.0077 0.009 0.4149
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Schistosoma mansoni RAR-like nuclear receptor 0.0085 0.0106 0.0125
Echinococcus multilocularis Nuclear hormone receptor HR96 0.004 0.0017 0.0011
Mycobacterium ulcerans ion transport protein 0.0136 0.0206 0.1245
Loa Loa (eye worm) hypothetical protein 0.0093 0.0122 0.0143
Schistosoma mansoni tar DNA-binding protein 0.007 0.0076 0.0088
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0017 0.0011
Echinococcus multilocularis ecdysone induced protein 78C 0.0085 0.0106 0.01
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0136 0.0206 0.1226
Leishmania major hypothetical protein, conserved 0.0136 0.0206 1
Giardia lamblia Replication factor C, subunit 1 0.0052 0.0039 0.1264
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.001 0.0151
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0037 0.0011 0.0207
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0136 0.0206 0.1072
Loa Loa (eye worm) hepatopoietin HPO2 0.0037 0.0011 0.0005
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0629 0.1178 0.1457
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0066 0.006
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0085 0.0106 0.01
Echinococcus granulosus thyroid hormone receptor alpha 0.004 0.0017 0.0014
Entamoeba histolytica acyl-CoA synthetase, putative 0.0125 0.0184 0.1539
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0085 0.0106 0.0125
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0136 0.0206 0.1226
Schistosoma mansoni hypothetical protein 0.0065 0.0066 0.0074
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.001 0.0151
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0066 0.036
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.0011 0.0207
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.008 0.0943
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0085 0.0106 0.061
Loa Loa (eye worm) hypothetical protein 0.0072 0.008 0.009
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.008 0.0391
Loa Loa (eye worm) patched family protein 0.0038 0.0012 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.008 0.3651
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Toxoplasma gondii patched family protein 0.0038 0.0012 0.0233
Echinococcus granulosus snurportin 1 0.0647 0.1214 0.1502
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0015 0.0408
Onchocerca volvulus 0.004 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0085 0.0106 0.0123
Toxoplasma gondii HEAT repeat-containing protein 0.0061 0.0057 0.2521
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Loa Loa (eye worm) patched family protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Brugia malayi hypothetical protein 0.0038 0.0012 0.0029
Loa Loa (eye worm) TAR-binding protein 0.007 0.0076 0.0086
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0037 0.001 0.0399
Brugia malayi photoreceptor-specific nuclear receptor 0.0085 0.0106 0.061
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0066 0.036
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0136 0.0206 1
Schistosoma mansoni alpha-glucosidase 0.0137 0.0207 0.025
Brugia malayi nuclear hormone receptor family member odr-7 0.004 0.0017 0.0061
Echinococcus granulosus expressed conserved protein 0.0582 0.1085 0.1342
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0136 0.0206 0.02
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Leishmania major 4-coumarate:coa ligase-like protein 0.0125 0.0184 0.8914
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Brugia malayi hypothetical protein 0.0038 0.0012 0.0029
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.0011 0.0207
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0112 0.1324
Entamoeba histolytica hypothetical protein 0.0052 0.0039 0.028
Echinococcus multilocularis protein patched 0.0266 0.0462 0.0456
Echinococcus multilocularis Niemann Pick C1 protein 0.0619 0.1159 0.1154
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Brugia malayi beta-lactamase 0.0072 0.008 0.0448
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0168 0.0269 0.0325
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Echinococcus granulosus nibrin 0.0052 0.0039 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0085 0.0106 0.061
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0266 0.0462 0.0565
Brugia malayi AMP-binding enzyme family protein 0.0125 0.0184 0.1093
Brugia malayi nuclear receptor NHR-67 0.004 0.0017 0.0061
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.0251 0.0303
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.004
Onchocerca volvulus 0.0085 0.0106 0.0518
Loa Loa (eye worm) hypothetical protein 0.0125 0.0184 0.022
Onchocerca volvulus Protein ultraspiracle homolog 0.0085 0.0106 0.0518
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0085 0.0106 0.0518
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0037 0.001 0.0151
Mycobacterium tuberculosis Conserved protein 0.0072 0.008 0.0943
Brugia malayi beta-lactamase family protein 0.0072 0.008 0.0448
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.008 0.0943
Brugia malayi nuclear receptor NHR-88 0.004 0.0017 0.0061
Onchocerca volvulus Protein patched homolog 0.0038 0.0012 0.0009
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0037 0.001 0.0399
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0028 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.0125 0.0184 0.1108
Echinococcus multilocularis importin subunit beta 1 0.0061 0.0057 0.0051
Loa Loa (eye worm) hypothetical protein 0.0077 0.009 0.0103
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0017 0.0014
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0066 0.0074
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0052 0.0039 0.162
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.008 0.3651
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0085 0.0106 0.061
Onchocerca volvulus 0.0136 0.0206 0.1057
Mycobacterium ulcerans hypothetical protein 0.0125 0.0184 0.1108
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0136 0.0206 0.1072
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0037 0.001 0.0004
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0066 0.0074
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0136 0.0206 0.1226
Trypanosoma cruzi hypothetical protein, conserved 0.0052 0.0039 0.162
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0093 0.0122 0.1443
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0066 0.0073
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Brugia malayi hypothetical protein 0.0045 0.0027 0.012
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0136 0.0206 0.02
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.008 0.3651
Brugia malayi hypothetical protein 0.0052 0.0039 0.0199
Schistosoma mansoni twik family of potassium channels-related 0.0136 0.0206 0.0249
Onchocerca volvulus 0.0125 0.0184 0.0941
Brugia malayi hypothetical protein 0.0228 0.0387 0.234
Brugia malayi AMP-binding enzyme family protein 0.0037 0.001 0.0018
Leishmania major 4-coumarate:coa ligase-like protein 0.0125 0.0184 0.8914
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0003 0.0034
Echinococcus multilocularis potassium channel subfamily K 8 0.0136 0.0206 0.02
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Giardia lamblia Hypothetical protein 0.0136 0.0206 1
Loa Loa (eye worm) hypothetical protein 0.0205 0.0342 0.0416
Schistosoma mansoni thyroid hormone receptor 0.0464 0.0853 0.1053
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Brugia malayi hypothetical protein 0.0168 0.0269 0.1613
Brugia malayi hypothetical protein 0.004 0.0017 0.0061
Brugia malayi protein C24B5.3 0.0038 0.0012 0.0029
Echinococcus granulosus histone lysine methyltransferase setb 0.0141 0.0215 0.026
Echinococcus granulosus Niemann Pick C1 protein 0.0885 0.1684 0.2085
Schistosoma mansoni calcium-activated potassium channel 0.2653 0.5173 0.6422
Schistosoma mansoni cellular tumor antigen P53 0.015 0.0233 0.0283
Echinococcus multilocularis replication factor c subunit 1 0.0052 0.0039 0.0034
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0085 0.0106 0.01
Loa Loa (eye worm) TWK-28 protein 0.0136 0.0206 0.0247
Echinococcus multilocularis expressed conserved protein 0.0582 0.1085 0.108
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0136 0.0206 0.0247
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.008 0.0391
Echinococcus granulosus ecdysone induced protein 78C 0.0085 0.0106 0.0125
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0136 0.0206 0.1226
Echinococcus multilocularis thyroid hormone receptor alpha 0.0464 0.0853 0.0848
Mycobacterium ulcerans acyl-CoA synthetase 0.0125 0.0184 0.1108
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0085 0.0106 0.0125
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0035 0.0148
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0136 0.0206 0.1226
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi nuclear hormone receptor 0.004 0.0017 0.0061
Onchocerca volvulus 0.004 0.0017 0.0038
Schistosoma mansoni ap endonuclease 0.0039 0.0015 0.0012
Echinococcus multilocularis protein dispatched 1 0.0303 0.0536 0.0531
Toxoplasma gondii ABC1 family protein 0.0072 0.008 0.3651
Schistosoma mansoni alpha glucosidase 0.0035 0.0007 0.0002
Brugia malayi RNA, U transporter 1 0.0172 0.0278 0.1668
Brugia malayi topoisomerase 0.0052 0.0039 0.0199
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0136 0.0206 1
Loa Loa (eye worm) patched family protein 0.0038 0.0012 0.0006
Brugia malayi RNA binding protein 0.007 0.0076 0.0428
Schistosoma mansoni inositol monophosphatase 0.0037 0.001 0.0006
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.008 0.0943
Loa Loa (eye worm) nuclear receptor nhr-7B 0.004 0.0017 0.0012
Schistosoma mansoni hypothetical protein 0.4112 0.8051 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0085 0.0106 0.061
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.008 0.0391
Echinococcus granulosus potassium channel subfamily K 8 0.0136 0.0206 0.0249
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.008 0.0943
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0125 0.0184 0.1108
Toxoplasma gondii propionate-CoA ligase 0.0037 0.001 0.0151
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Trichomonas vaginalis replication factor C large subunit, putative 0.0052 0.0039 0.0174
Loa Loa (eye worm) glutaminase 2 0.0834 0.1584 0.196
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Onchocerca volvulus 0.0123 0.018 0.0918
Leishmania major importin beta-1 subunit, putative 0.0049 0.0035 0.1384
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0136 0.0206 0.1226
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0112 0.1324
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0037 0.001 0.0119
Mycobacterium ulcerans acyl-CoA synthetase 0.0125 0.0184 0.1108
Brugia malayi Nuclear hormone receptor E75 0.004 0.0017 0.0061
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0136 0.0206 0.1226
Trypanosoma cruzi hypothetical protein, conserved 0.0052 0.0039 0.162
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Echinococcus granulosus potassium channel subfamily K 0.0136 0.0206 0.0249
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0024
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Schistosoma mansoni hypothetical protein 0.0647 0.1214 0.1502
Brugia malayi Nuclear hormone receptor-like 1 0.0085 0.0106 0.061
Loa Loa (eye worm) hypothetical protein 0.0093 0.0122 0.0143
Schistosoma mansoni zinc finger protein 0.004 0.0017 0.0014
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0037 0.001 0.0119
Echinococcus multilocularis microtubule associated protein 2 0.2798 0.5458 0.5455
Onchocerca volvulus 0.0136 0.0206 0.1057
Brugia malayi Augmenter of liver regeneration 0.0037 0.0011 0.0025
Echinococcus multilocularis calcium activated potassium channel variant 0.0136 0.0206 0.02
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Echinococcus multilocularis twik family of potassium channels 0.0136 0.0206 0.02
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0027 0.012
Schistosoma mansoni ran 0.0045 0.0026 0.0025
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0085 0.0106 0.0125
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0037 0.001 0.0005
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.001 0.0171
Entamoeba histolytica Ran family GTPase 0.0045 0.0026 0.0161
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Schistosoma mansoni ran 0.0045 0.0026 0.0025
Onchocerca volvulus 0.0038 0.0012 0.0009
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.004 0.0017 0.0014
Schistosoma mansoni nuclear hormone receptor 0.004 0.0017 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0072 0.008 0.3553
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.001 0.0151
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Schistosoma mansoni nuclear hormone receptor 0.0085 0.0106 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0085 0.0106 0.0123
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0085 0.0106 0.0125
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.008 0.0442
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0037 0.001 0.0151
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.008 0.0448
Brugia malayi hypothetical protein 0.004 0.0017 0.0061
Mycobacterium tuberculosis Conserved protein 0.0072 0.008 0.0943
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0136 0.0206 0.1226
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0039 0.0174
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.004
Echinococcus granulosus Niemann Pick C1 protein 0.0619 0.1159 0.1434
Loa Loa (eye worm) hypothetical protein 0.0065 0.0066 0.0073
Brugia malayi nuclear receptor NHR-88 0.0085 0.0106 0.061
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0379 0.0685 0.068
Loa Loa (eye worm) hypothetical protein 0.004 0.0016 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0141 0.0215 0.026
Toxoplasma gondii ion channel protein 0.0136 0.0206 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0141 0.0215 0.021
Toxoplasma gondii ion channel protein 0.0136 0.0206 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Loa Loa (eye worm) nuclear receptor NHR-67 0.004 0.0017 0.0012
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0027 0.012
Schistosoma mansoni transcription factor LCR-F1 0.0228 0.0387 0.0473
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.008 0.0092
Trichomonas vaginalis esterase, putative 0.0072 0.008 0.0391
Brugia malayi hypothetical protein 0.0038 0.0012 0.0029
Onchocerca volvulus 0.0038 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0072 0.008 0.009
Loa Loa (eye worm) patched family protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0205 0.0342 0.0416
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0052 0.0039 0.0174
Schistosoma mansoni hypothetical protein 0.0065 0.0066 0.0074
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Mycobacterium ulcerans lipase LipD 0.0072 0.008 0.0442
Echinococcus multilocularis sterol regulatory element binding protein 0.0266 0.0462 0.0456
Loa Loa (eye worm) hypothetical protein 0.4112 0.8051 1
Brugia malayi Pre-SET motif family protein 0.0123 0.018 0.1068
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Echinococcus granulosus GPCR family 2 0.0065 0.0066 0.0074
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0026 0.0934
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0085 0.0106 0.0123
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0074 0.0083 0.0094
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0136 0.0206 1
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0136 0.0206 1
Echinococcus granulosus tumor protein p63 0.1024 0.1958 0.2427
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0125 0.0184 0.2181
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.001 0.0016
Echinococcus granulosus tar DNA binding protein 0.007 0.0076 0.0088
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0052 0.0039 0.162
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0024
Onchocerca volvulus 0.0976 0.1863 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.001 0.0004
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.001 0.0119
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0123 0.018 0.0217
Loa Loa (eye worm) hypothetical protein 0.0325 0.058 0.0712
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Echinococcus multilocularis Niemann Pick C1 protein 0.0885 0.1684 0.1679
Loa Loa (eye worm) hypothetical protein 0.0093 0.0122 0.0143
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0052 0.0039 0.0199
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0085 0.0106 0.01
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0015 0.0032
Loa Loa (eye worm) steroid hormone receptor 0.0085 0.0106 0.0123
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0037 0.001 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0085 0.0106 0.0123
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.008 0.0943
Loa Loa (eye worm) TWK-7 protein 0.0136 0.0206 0.0247
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.004 0.0017 0.0038
Plasmodium vivax potassium channel, putative 0.0136 0.0206 1
Onchocerca volvulus 0.0038 0.0012 0.0009
Trichomonas vaginalis set domain proteins, putative 0.0976 0.1863 1
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.001 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0028 0.0028
Echinococcus multilocularis twik family of potassium channels 0.0136 0.0206 0.02
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0045 0.0027 0.0024
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0026 0.0934
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.001 0.0171
Brugia malayi Patched protein homolog 1 0.0038 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Brugia malayi Patched related family protein 12 0.0038 0.0012 0.0029
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0015 0.0261
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0045 0.0026 0.0795
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0028 0.0028
Onchocerca volvulus 0.0072 0.008 0.0376
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi ecdysteroid receptor 0.0085 0.0106 0.061
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0085 0.0106 0.01
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0205 0.0342 0.2064
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0037 0.001 0.0119
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0647 0.1214 0.1501
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0039 0.0174
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi nuclear receptor RXR 0.004 0.0017 0.0061
Plasmodium vivax importin-beta 2, putative 0.0061 0.0057 0.2407
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.001 0.0018
Toxoplasma gondii Erv1 / Alr family protein 0.0037 0.0011 0.0207
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.001 0.0016
Echinococcus granulosus sterol regulatory element binding protein 0.0266 0.0462 0.0567
Brugia malayi AMP-binding enzyme family protein 0.0037 0.001 0.0018
Mycobacterium ulcerans beta-lactamase 0.0072 0.008 0.0442
Loa Loa (eye worm) hypothetical protein 0.0093 0.0122 0.0143
Echinococcus multilocularis snurportin 1 0.0647 0.1214 0.1209
Brugia malayi orphan nuclear receptor NR2E1 0.004 0.0017 0.0061
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0136 0.0206 0.1226
Onchocerca volvulus 0.0072 0.008 0.0376
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Loa Loa (eye worm) RNA binding protein 0.007 0.0076 0.0086
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.004
Onchocerca volvulus 0.015 0.0233 0.1205
Leishmania major hypothetical protein, conserved 0.0037 0.0011 0.0207
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0125 0.0184 0.1108
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0136 0.0206 0.0249
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0015 0.001
Treponema pallidum DNA ligase (lig) 0.0052 0.0039 1
Leishmania major potassium channel subunit-like protein 0.0136 0.0206 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0085 0.0106 0.0125
Echinococcus granulosus small conductance calcium activated potassium 0.4112 0.8051 1
Trypanosoma cruzi ion transport protein, putative 0.0136 0.0206 1
Schistosoma mansoni chromosome transmission fidelity factor 0.0052 0.0039 0.0042
Plasmodium vivax replication factor C subunit 1, putative 0.0052 0.0039 0.1492
Schistosoma mansoni microtubule-associated protein tau 0.2798 0.5458 0.6777
Echinococcus multilocularis nuclear receptor nhr 48 0.004 0.0017 0.0011
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.001 0.0171
Loa Loa (eye worm) oxidoreductase 0.0037 0.001 0.0004
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0015 0.0044
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0066 0.006
Brugia malayi hypothetical protein 0.0038 0.0012 0.0029
Schistosoma mansoni hypothetical protein 0.0256 0.0443 0.0543
Brugia malayi hypothetical protein 0.0136 0.0206 0.1226
Brugia malayi steroid hormone receptor 0.0085 0.0106 0.061
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.008 0.009
Onchocerca volvulus 0.0038 0.0012 0.0009
Schistosoma mansoni bromodomain containing protein 0.0066 0.0068 0.0077
Brugia malayi Myosin head containing protein 0.0038 0.0012 0.0029
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.006 0.0055
Brugia malayi Niemann-Pick C1 protein precursor 0.0619 0.1159 0.7104
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0037 0.0011 0.0207
Entamoeba histolytica hypothetical protein 0.0049 0.0035 0.0239
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi ecdysone receptor 0.004 0.0017 0.0061
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0136 0.0206 0.2437
Mycobacterium ulcerans glutaminase 0.0834 0.1584 1
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0039 0.0174
Entamoeba histolytica hypothetical protein 0.0228 0.0387 0.3294
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0085 0.0106 0.01
Trichomonas vaginalis glutaminase, putative 0.0834 0.1584 0.8496
Echinococcus multilocularis potassium channel subfamily K 8 0.0136 0.0206 0.02
Plasmodium vivax potassium channel, putative 0.0136 0.0206 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0085 0.0106 0.0123
Mycobacterium leprae Probable lipase LipE 0.0072 0.008 0.4233
Trichomonas vaginalis importin beta-1, putative 0.0049 0.0035 0.0148
Loa Loa (eye worm) hypothetical protein 0.0072 0.008 0.009
Schistosoma mansoni hypothetical protein 0.0256 0.0443 0.0543
Brugia malayi tailless protein 0.004 0.0017 0.0061
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0007 0.0001
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0045 0.0026 0.0548
Loa Loa (eye worm) hypothetical protein 0.0061 0.0057 0.0062
Schistosoma mansoni coup transcription factor 0.0085 0.0106 0.0125
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.009 0.4149
Leishmania major hypothetical protein, conserved 0.0072 0.008 0.3651
Toxoplasma gondii exonuclease III APE 0.0039 0.0015 0.0408
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0251 0.0245
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0057 0.2521
Echinococcus multilocularis small conductance calcium activated potassium 0.4112 0.8051 0.805
Loa Loa (eye worm) hypothetical protein 0.0093 0.0122 0.0143
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0039 0.0174
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0045 0.0026 0.0795
Toxoplasma gondii patched family protein 0.0038 0.0012 0.0233
Leishmania major 4-coumarate:coa ligase-like protein 0.0125 0.0184 0.8914
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0037 0.001 0.0026
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.008 0.0092
Loa Loa (eye worm) beta-lactamase 0.0072 0.008 0.009
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0012
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0057 0.2521
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Echinococcus multilocularis tumor protein p63 0.1024 0.1958 0.1953
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0037 0.001 0.0018
Trichomonas vaginalis ran, putative 0.0045 0.0026 0.01
Loa Loa (eye worm) DR-78 0.004 0.0017 0.0012
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.001 0.0171
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0228 0.0387 0.0381
Echinococcus granulosus twik family of potassium channels 0.0136 0.0206 0.0249
Loa Loa (eye worm) hypothetical protein 0.0266 0.0462 0.0565
Brugia malayi DKFZp564C0469 protein 0.0052 0.0039 0.0199
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0136 0.0206 0.1072
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0045 0.0026 0.0934
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.004 0.0017 0.0011
Mycobacterium tuberculosis Conserved protein 0.0072 0.008 0.0943
Schistosoma mansoni tar DNA-binding protein 0.007 0.0076 0.0088
Plasmodium falciparum lipid/sterol:H+ symporter 0.0038 0.0012 0.0084
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0045 0.0027 0.0026
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0045 0.0026 0.002
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.008 0.0391
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0136 0.0206 0.1072
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0085 0.0106 0.0125
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0045 0.0026 0.0023
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0204 0.0341 0.0417
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0085 0.0106 0.0125
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0251 0.0245
Loa Loa (eye worm) glutaminase 0.0834 0.1584 0.196
Brugia malayi Bromodomain containing protein 0.0078 0.0092 0.0522
Loa Loa (eye worm) hypothetical protein 0.1255 0.2414 0.2992
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0112 0.1324
Brugia malayi hypothetical protein 0.0077 0.009 0.0509
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0037 0.001 0.0018
Schistosoma mansoni retinoic acid receptor RXR 0.0204 0.0341 0.0417
Mycobacterium ulcerans transmembrane cation transporter 0.0136 0.0206 0.1245
Plasmodium vivax SET domain protein, putative 0.0123 0.018 0.8688
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.001 0.0151
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0085 0.0106 0.0125
Loa Loa (eye worm) hypothetical protein 0.0038 0.0012 0.0006
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.0251 0.1501
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Onchocerca volvulus 0.0136 0.0206 0.1057
Schistosoma mansoni importin beta-1 0.0061 0.0057 0.0064
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.001 0.0399
Schistosoma mansoni hypothetical protein 0.0379 0.0685 0.0844
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.0251 0.0304
Schistosoma mansoni acetyl-CoA synthetase 0.0037 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.008 0.0391
Leishmania major ion transport protein-like protein 0.0136 0.0206 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0106 0.0123
Entamoeba histolytica acyl-CoA synthetase, putative 0.0125 0.0184 0.1539
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0125 0.0184 1
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.004 0.0017 0.0038
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0136 0.0206 0.1226
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0037 0.001 0.0151
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0085 0.0106 0.01
Trypanosoma cruzi hypothetical protein, conserved 0.0136 0.0206 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.001 0.0004
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0159 0.0252 0.0246
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0136 0.0206 0.1072
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0037 0.001 0.0119
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Echinococcus granulosus Nuclear hormone receptor HR96 0.004 0.0017 0.0014
Plasmodium falciparum acyl-CoA synthetase 0.0093 0.0122 0.5713
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Echinococcus granulosus GTP binding nuclear protein Ran 0.0045 0.0026 0.0025
Schistosoma mansoni steroid hormone receptor ad4bp 0.0085 0.0106 0.0125
Loa Loa (eye worm) hypothetical protein 0.0136 0.0206 0.0247
Toxoplasma gondii patched family protein 0.0038 0.0012 0.0233
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0136 0.0206 0.1226
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.001 0.0018
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0037 0.0011 0.0058
Brugia malayi Patched family protein 0.0038 0.0012 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0085 0.0106 0.061

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

5 literature references were collected for this gene.

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