Detailed information for compound 574065

Basic information

Technical information
  • TDR Targets ID: 574065
  • Name: 4-(dimethylamino)benzoate
  • MW: 164.181 | Formula: C9H10NO2-
  • H donors: 0 H acceptors: 2 LogP: 2.22 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(c1ccc(cc1)C(=O)[O-])C
  • InChi: 1S/C9H11NO2/c1-10(2)8-5-3-7(4-6-8)9(11)12/h3-6H,1-2H3,(H,11,12)/p-1
  • InChiKey: YDIYEOMDOWUDTJ-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

  • 4-(dimethylamino)benzoic acid
  • ZINC00388582

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0036 0.0029
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0016 0.0016
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0177 0.0637
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0055 0.0251
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0067 0.0197
Echinococcus multilocularis snurportin 1 0.0305 0.1527 0.1527
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0036 0.0036
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0122 0.0567
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0129 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0147 0.0684
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0036 0.0029
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0055 0.0053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0036 0.0036
Echinococcus granulosus cyclin dependent kinase 1 0.0421 0.2134 0.2134
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0122 0.0567
Brugia malayi hypothetical protein 0.0025 0.0067 0.0059
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0054 0.0217 0.0217
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0142 0.0674 0.0674
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0067 0.011
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0254 0.1184
Schistosoma mansoni hypothetical protein 0.0039 0.0139 0.0132
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0061 0.0254 0.1005
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0067 0.011
Schistosoma mansoni protein kinase 0.0098 0.0444 0.0436
Brugia malayi Erv1 / Alr family protein 0.0028 0.0082 0.0075
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0036
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0067 0.011
Brugia malayi RNA recognition motif domain containing protein 0.0069 0.0292 0.0285
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0062 0.0257 0.0249
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0122 0.5
Echinococcus multilocularis lamin dm0 0.0026 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0036 0.0122 0.0122
Echinococcus multilocularis microtubule associated protein 2 0.1558 0.8073 0.8073
Toxoplasma gondii Erv1 / Alr family protein 0.0178 0.0866 0.3934
Schistosoma mansoni hypothetical protein 0.0451 0.2289 0.2283
Echinococcus granulosus glycoprotein Antigen 5 0.0341 0.1714 0.1714
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0122 0.0122
Trypanosoma brucei cdc2-related kinase 1 0.0421 0.2134 1
Loa Loa (eye worm) transcription factor SMAD2 0.0232 0.1143 0.1143
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0697 0.069
Entamoeba histolytica hypothetical protein 0.0105 0.0483 0.2104
Loa Loa (eye worm) hepatopoietin HPO2 0.0178 0.0866 0.0866
Loa Loa (eye worm) hypothetical protein 0.0026 0.0068 0.0068
Echinococcus granulosus mixed lineage leukemia protein mll 0.0014 0.0008 0.0008
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0036 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0036 0.0036
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0341 0.1714 0.1708
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0036 0.0036
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0158 0.0736
Brugia malayi hypothetical protein 0.0105 0.0483 0.0476
Echinococcus multilocularis cyclin dependent kinase 5 0.0421 0.2134 0.2134
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0674 0.0674
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0431 0.0431
Echinococcus multilocularis casein kinase I alpha 0.0054 0.0217 0.0217
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0129 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0036 0.0029
Echinococcus granulosus carbonic anhydrase 0.0087 0.0386 0.0386
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0061 0.0254 0.1005
Brugia malayi RNA, U transporter 1 0.0081 0.0358 0.0351
Trichomonas vaginalis esterase, putative 0.0036 0.0122 0.0567
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0083 0.0275
Loa Loa (eye worm) hypothetical protein 0.0608 0.3107 0.3107
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0061 0.0254 0.1005
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1927 1 1
Brugia malayi MAP kinase sur-1 0.0061 0.0254 0.0246
Echinococcus granulosus mitogen activated protein kinase 0.0061 0.0254 0.0254
Mycobacterium tuberculosis Possible penicillin-binding protein 0.023 0.1137 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0644 0.0644
Leishmania major importin beta-1 subunit, putative 0.0023 0.0055 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0122 0.0375
Echinococcus multilocularis sulfhydryl oxidase 1 0.0028 0.0082 0.0082
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0087 0.0386 0.0379
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0036 0.0029
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0036 0.0036
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0184 0.0896 0.0896
Schistosoma mansoni hypothetical protein 0.0039 0.0139 0.0132
Brugia malayi intermediate filament protein 0.0026 0.0071 0.0064
Brugia malayi Calcitonin receptor-like protein seb-1 0.0196 0.0955 0.0949
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0087 0.0386 0.0379
Loa Loa (eye worm) hypothetical protein 0.0134 0.0632 0.0632
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0044 0.0044
Echinococcus granulosus smad 0.0016 0.0016 0.0016
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0087 0.0386 0.0379
Echinococcus multilocularis cyclin dependent kinase 1 0.0421 0.2134 0.2134
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0254 0.0246
Toxoplasma gondii Erv1 / Alr family protein 0.0028 0.0082 0.0183
Leishmania major hypothetical protein, conserved 0.0036 0.0122 0.0375
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0036 0.0036
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0644 0.0644
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1672 0.8666 0.8666
Echinococcus granulosus transmembrane protease serine 3 0.0341 0.1714 0.1714
Trypanosoma cruzi casein kinase, putative 0.0054 0.0217 0.0827
Schistosoma mansoni ran 0.0021 0.0044 0.0036
Brugia malayi hypothetical protein 0.023 0.1136 0.113
Onchocerca volvulus 0.0341 0.1714 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0257 0.0257
Schistosoma mansoni smad1 5 8 and 0.0016 0.0016 0.0009
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0257 0.0257
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0122 0.0122
Loa Loa (eye worm) MH2 domain-containing protein 0.0232 0.1143 0.1143
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0083 0.0083
Giardia lamblia Kinase, CMGC MAPK 0.0061 0.0254 0.1005
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0122 0.0115
Echinococcus granulosus geminin 0.0333 0.1675 0.1675
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0036 0.0029
Brugia malayi cell division control protein 2 homolog 0.0421 0.2134 0.2128
Schistosoma mansoni serine/threonine protein kinase 0.1927 1 1
Echinococcus granulosus cyclin dependent kinase 5 0.0421 0.2134 0.2134
Echinococcus granulosus Smad4 0.0016 0.0016 0.0016
Brugia malayi steroid hormone receptor 0.002 0.0036 0.0029
Toxoplasma gondii Erv1 / Alr family protein 0.0178 0.0866 0.3934
Echinococcus multilocularis protein dispatched 1 0.0047 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0026 0.0071 0.0071
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0147 0.0147
Echinococcus multilocularis rho associated protein kinase 0.018 0.0876 0.0876
Plasmodium vivax casein kinase 1, putative 0.0054 0.0217 0.0827
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0036 0.0036
Echinococcus granulosus intermediate filament protein 0.0026 0.0071 0.0071
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0036 0.0029
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0028 0.0082 0.0183
Schistosoma mansoni ap endonuclease 0.0037 0.0129 0.0122
Loa Loa (eye worm) hypothetical protein 0.0608 0.3107 0.3107
Echinococcus multilocularis casein kinase i 0.0054 0.0217 0.0217
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0674 0.0666
Loa Loa (eye worm) hypothetical protein 0.0341 0.1714 0.1714
Brugia malayi hypothetical protein 0.0341 0.1714 0.1708
Loa Loa (eye worm) hypothetical protein 0.0036 0.0122 0.0122
Trypanosoma cruzi cdc2-related kinase 1 0.0421 0.2134 1
Onchocerca volvulus 0.0168 0.0813 0.4631
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0026 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0036 0.0029
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0054 0.0217 0.0217
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0042 0.0153 0.0526
Brugia malayi RNA binding protein 0.0069 0.0292 0.0285
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0036 0.0036
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0044 0.0044
Schistosoma mansoni survival motor neuron protein 0.0047 0.0179 0.0171
Brugia malayi CHE-14 protein 0.0041 0.0147 0.014
Schistosoma mansoni cercarial elastase (S01 family) 0.0341 0.1714 0.1708
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0036 0.0036
Brugia malayi MH1 domain containing protein 0.0016 0.0016 0.0009
Trypanosoma cruzi cdc2-related kinase 1 0.0421 0.2134 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0026 0.0026
Plasmodium falciparum casein kinase 1 0.0054 0.0217 0.0827
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0036 0.0122 0.0122
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0158 0.0736
Echinococcus multilocularis casein kinase I alpha 0.0054 0.0217 0.0217
Schistosoma mansoni cercarial elastase (S01 family) 0.0341 0.1714 0.1708
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0257 0.0257
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0674 0.0674
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0087 0.0386 0.0386
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0341 0.1714 0.1708
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0147 0.0147
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0292 0.0285
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0061 0.0254 0.1084
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0341 0.1714 0.1708
Echinococcus multilocularis cyclin dependent kinase 0.0421 0.2134 0.2134
Toxoplasma gondii ABC1 family protein 0.0036 0.0122 0.0375
Echinococcus granulosus carbonic anhydrase 0.0087 0.0386 0.0386
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0036 0.0029
Echinococcus granulosus lamin 0.0026 0.0071 0.0071
Echinococcus multilocularis mitogen activated protein kinase 3 0.0061 0.0254 0.0254
Schistosoma mansoni hypothetical protein 0.0047 0.0179 0.0171
Loa Loa (eye worm) hypothetical protein 0.0341 0.1714 0.1714
Echinococcus granulosus enteropeptidase 0.0341 0.1714 0.1714
Loa Loa (eye worm) hypothetical protein 0.0062 0.0257 0.0257
Echinococcus granulosus importin subunit beta 1 0.0029 0.0083 0.0083
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0054 0.0217 0.0217
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0036 0.0036
Echinococcus multilocularis carbonic anhydrase 0.0087 0.0386 0.0386
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0129 0.041
Onchocerca volvulus 0.0036 0.0122 0.0512
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0129 0.5
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0036 0.0036
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0098 0.0444 0.1913
Loa Loa (eye worm) hypothetical protein 0.0036 0.0122 0.0122
Echinococcus multilocularis lamin 0.0026 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.0062 0.0257 0.0249
Trichomonas vaginalis CK1 family protein kinase 0.0054 0.0217 0.101
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0129 0.0122
Echinococcus multilocularis dnaJ subfamily B 0.0451 0.2289 0.2289
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0036 0.0029
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0055 0.0251
Echinococcus granulosus casein kinase I alpha 0.0054 0.0217 0.0217
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0147 0.0147
Schistosoma mansoni cercarial elastase (S01 family) 0.0341 0.1714 0.1708
Echinococcus multilocularis carbonic anhydrase 0.0087 0.0386 0.0386
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0036 0.0036
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0179 0.0172
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0178 0.0866 0.0866
Mycobacterium ulcerans hypothetical protein 0.0341 0.1714 1
Schistosoma mansoni hypothetical protein 0.0333 0.1675 0.1668
Echinococcus multilocularis casein kinase I alpha 0.0054 0.0217 0.0217
Plasmodium falciparum importin beta, putative 0.0029 0.0083 0.0189
Onchocerca volvulus 0.0057 0.0231 0.1162
Schistosoma mansoni cercarial elastase (S01 family) 0.0341 0.1714 0.1708
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0142 0.0674 0.0667
Loa Loa (eye worm) hypothetical protein 0.0087 0.0386 0.0386
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0007 0.0007
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0536 0.2733 0.2733
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0421 0.2134 0.2134
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0431 0.1851
Onchocerca volvulus Sulfhydryl oxidase homolog 0.0028 0.0082 0.0273
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0254 0.1184
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0341 0.1714 0.1714
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0178 0.0866 0.3934
Echinococcus multilocularis Mastin 0.0341 0.1714 0.1714
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0421 0.2134 1
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0217 0.0209
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0036
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.0565 0.0557
Brugia malayi beta-lactamase 0.0036 0.0122 0.0115
Brugia malayi Trypsin-like protease protein 5 0.0341 0.1714 0.1708
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0061 0.0254 0.1005
Echinococcus granulosus casein kinase I alpha 0.0054 0.0217 0.0217
Trypanosoma cruzi casein kinase, putative 0.0054 0.0217 0.0827
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0292 0.0285
Echinococcus granulosus cyclin dependent kinase 0.0421 0.2134 0.2134
Echinococcus multilocularis casein kinase I delta 0.0054 0.0217 0.0217
Trichomonas vaginalis CK1 family protein kinase 0.0054 0.0217 0.101
Brugia malayi MH2 domain containing protein 0.0016 0.0016 0.0009
Echinococcus granulosus FTZ F1 alpha 0.002 0.0036 0.0036
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0157 0.0752 0.3447
Echinococcus granulosus dual specificity mitogen activated protein 0.0098 0.0444 0.0444
Loa Loa (eye worm) hypothetical protein 0.0409 0.2071 0.2071
Schistosoma mansoni hypothetical protein 0.0062 0.0257 0.0249
Brugia malayi CXXC zinc finger family protein 0.0057 0.0231 0.0224
Entamoeba histolytica cell division protein kinase 2, putative 0.0421 0.2134 1
Echinococcus multilocularis GPCR, family 2 0.0062 0.0257 0.0257
Loa Loa (eye worm) trypsin family protein 0.0341 0.1714 0.1714
Schistosoma mansoni nuclear hormone receptor 0.002 0.0036 0.0029
Brugia malayi hypothetical protein 0.0016 0.002 0.0012
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0098 0.0444 0.1913
Echinococcus granulosus tar DNA binding protein 0.0069 0.0292 0.0292
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0178 0.0866 0.3987
Echinococcus multilocularis dual specificity mitogen activated protein 0.0098 0.0444 0.0444
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0177 0.0637
Trichomonas vaginalis CK1 family protein kinase 0.0054 0.0217 0.101
Schistosoma mansoni quiescin q6-related sulfhydryl oxidase 0.0028 0.0082 0.0074
Loa Loa (eye worm) Erv1/Alr family protein 0.0028 0.0082 0.0082
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0061 0.0254 0.0254
Brugia malayi Trypsin family protein 0.0341 0.1714 0.1708
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0036
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0184 0.0896 0.0889
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0036 0.0036
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0158 0.0158
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0036 0.0029
Schistosoma mansoni carbonic anhydrase-related 0.0087 0.0386 0.0378
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0087 0.0386 0.0379
Onchocerca volvulus Sulfhydryl oxidase homolog 0.0028 0.0082 0.0273
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0087 0.0386 0.0379
Schistosoma mansoni importin beta-1 0.0029 0.0083 0.0075
Echinococcus multilocularis Smad4 0.0016 0.0016 0.0016
Brugia malayi Protein kinase domain containing protein 0.0421 0.2134 0.2128
Entamoeba histolytica cell division protein kinase 2, putative 0.0421 0.2134 1
Brugia malayi quiescin Q6 0.0028 0.0082 0.0075
Onchocerca volvulus 0.0026 0.0071 0.0207
Loa Loa (eye worm) carbonic anhydrase 3 0.0184 0.0896 0.0896
Echinococcus granulosus mitogen activated protein kinase 3 0.0061 0.0254 0.0254
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0421 0.2134 0.2134
Schistosoma mansoni carbonic anhydrase-related 0.0087 0.0386 0.0378
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0036 0.0036
Brugia malayi Smad1 0.0016 0.0016 0.0009
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1927 1 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0331 0.1662 0.7745
Schistosoma mansoni cercarial elastase (S01 family) 0.0341 0.1714 0.1708
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0341 0.1714 0.1708
Loa Loa (eye worm) hypothetical protein 0.0087 0.0386 0.0386
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0147 0.0147
Trypanosoma cruzi quiescin sulfhydryl oxidase, putative 0.0028 0.0082 0.0183
Echinococcus multilocularis musashi 0.0026 0.0071 0.0071
Schistosoma mansoni carbonic anhydrase-related 0.0087 0.0386 0.0378
Trichomonas vaginalis STE family protein kinase 0.0098 0.0444 0.2074
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0122 0.0114
Brugia malayi Protein kinase domain containing protein 0.0536 0.2733 0.2728
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0196 0.0955 0.0955
Echinococcus granulosus casein kinase I delta 0.0054 0.0217 0.0217
Brugia malayi nuclear receptor NHR-88 0.002 0.0036 0.0029
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0071 0.0071
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0129 0.041
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0122 0.0375
Echinococcus granulosus dnaJ subfamily B 0.0451 0.2289 0.2289
Trypanosoma cruzi quiescin sulfhydryl oxidase, putative 0.0028 0.0082 0.0183
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0697 0.0697
Schistosoma mansoni cercarial elastase (S01 family) 0.0341 0.1714 0.1708
Trypanosoma brucei casein kinase I, isoform 2 0.0054 0.0217 0.0908
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0069 0.0292 0.0292
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0036 0.0029
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0431 0.0431
Loa Loa (eye worm) hypothetical protein 0.0341 0.1714 0.1714
Trichomonas vaginalis CMGC family protein kinase 0.0421 0.2134 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0129 0.0129
Schistosoma mansoni smad1 5 8 and 0.0016 0.0016 0.0009
Schistosoma mansoni ap endonuclease 0.0037 0.0129 0.0122
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0129 0.0129
Mycobacterium leprae Probable lipase LipE 0.0036 0.0122 0.5
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0016 0.0009
Loa Loa (eye worm) quiescin Q6 0.0028 0.0082 0.0082
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0122 0.0567
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0876 0.0869
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0674 0.0666
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0016 0.0016
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0421 0.2134 0.2134
Entamoeba histolytica protein kinase, putative 0.0054 0.0217 0.0828
Trypanosoma cruzi cdc2-related kinase 3 0.0421 0.2134 1
Schistosoma mansoni cpg binding protein 0.006 0.0248 0.0241
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0044 0.0044
Echinococcus multilocularis protein patched 0.0041 0.0147 0.0147
Schistosoma mansoni thyroid hormone receptor 0.002 0.0036 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0036 0.0029
Echinococcus granulosus lamin dm0 0.0026 0.0071 0.0071
Echinococcus granulosus carbonic anhydrase 0.0087 0.0386 0.0386
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0231 0.0231
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0674 0.0674
Echinococcus granulosus casein kinase i 0.0054 0.0217 0.0217
Echinococcus multilocularis cpg binding protein 0.006 0.0248 0.0248
Plasmodium vivax importin-beta 2, putative 0.0029 0.0083 0.0189
Schistosoma mansoni smad1 5 8 and 0.0016 0.0016 0.0009
Plasmodium falciparum carbonic anhydrase 0.0087 0.0386 0.1637
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.1136 0.1136
Brugia malayi beta-lactamase family protein 0.0036 0.0122 0.0115
Echinococcus granulosus carbonic anhydrase II 0.0184 0.0896 0.0896
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0341 0.1714 0.1708
Schistosoma mansoni protein kinase 0.0054 0.0217 0.0209
Echinococcus multilocularis transmembrane protease serine 3 0.0341 0.1714 0.1714
Trypanosoma brucei carbonic anhydrase-like protein 0.0184 0.0896 0.413
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0129 0.5
Toxoplasma gondii hypothetical protein 0.0087 0.0386 0.1637
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.0752 0.3389
Loa Loa (eye worm) hypothetical protein 0.0028 0.0082 0.0082
Brugia malayi latrophilin 2 splice variant baaae 0.0134 0.0632 0.0625
Schistosoma mansoni transcription factor LCR-F1 0.0105 0.0483 0.0476
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0105 0.0483 0.0483
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0158 0.0548
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0067 0.011
Trichomonas vaginalis STE family protein kinase 0.0098 0.0444 0.2074
Entamoeba histolytica hypothetical protein 0.0023 0.0055 0.0053
Schistosoma mansoni lamin 0.0026 0.0071 0.0063
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.0257 0.0257
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0129 0.0601
Schistosoma mansoni hypothetical protein 0.0105 0.0483 0.0476
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0129 0.0601
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0036 0.0036
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0016 0.0016
Echinococcus granulosus cpg binding protein 0.006 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.005 0.0195 0.0195
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0044 0.0036
Trichomonas vaginalis CMGC family protein kinase 0.0421 0.2134 1
Schistosoma mansoni cpg binding protein 0.0057 0.0231 0.0224
Leishmania major mitochondrial DNA polymerase beta 0.0331 0.1662 0.7745
Onchocerca volvulus 0.018 0.0876 0.5007
Onchocerca volvulus Sulfhydryl oxidase homolog 0.0028 0.0082 0.0273
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0129 0.0045
Brugia malayi Importin beta-1 subunit 0.0029 0.0083 0.0076
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0184 0.0896 0.0889
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0341 0.1714 0.1708
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0036 0.0029
Schistosoma mansoni Smad4 0.0016 0.0016 0.0009
Schistosoma mansoni lamin 0.0026 0.0071 0.0063
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0014 0.0008 0.0008
Schistosoma mansoni coup transcription factor 0.002 0.0036 0.0029
Brugia malayi MH2 domain containing protein 0.0016 0.0016 0.0009
Echinococcus multilocularis muscleblind protein 1 0.0608 0.3107 0.3107
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0676 0.0676
Brugia malayi nuclear hormone receptor 0.002 0.0036 0.0029
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.0752 0.3389
Trypanosoma cruzi cdc2-related kinase 3 0.0421 0.2134 1
Schistosoma mansoni hypothetical protein 0.0062 0.0257 0.0249
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0178 0.0866 0.3934
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0184 0.0896 0.0889
Loa Loa (eye worm) hypothetical protein 0.0196 0.0955 0.0955
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0071 0.0064
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0036 0.0029
Schistosoma mansoni hypothetical protein 0.0341 0.1714 0.1708
Brugia malayi ecdysteroid receptor 0.002 0.0036 0.0029
Brugia malayi Augmenter of liver regeneration 0.0178 0.0866 0.0859
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0178 0.0866 0.0866
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.0008 0.0008
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0016 0.0016
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0184 0.0896 0.4078
Brugia malayi Trypsin family protein 0.0341 0.1714 0.1708
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0177 0.0637
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0036 0.0029
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0036 0.0036
Onchocerca volvulus 0.0026 0.0071 0.0207
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0054 0.0217 0.0217
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0036 0.0029
Schistosoma mansoni cercarial elastase (S01 family) 0.0341 0.1714 0.1708
Leishmania major hypothetical protein, conserved 0.0178 0.0866 0.3934
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0421 0.2134 1
Onchocerca volvulus 0.0036 0.0122 0.0512
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0341 0.1714 0.1708
Onchocerca volvulus 0.0341 0.1714 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0036
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0341 0.1714 0.1714
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0036
Giardia lamblia Kinase, CMGC CDK 0.0421 0.2134 1
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0292 0.0285
Onchocerca volvulus 0.0341 0.1714 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.0386 0.0386
Loa Loa (eye worm) beta-lactamase 0.0036 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0147
Entamoeba histolytica hypothetical protein 0.0105 0.0483 0.2104
Echinococcus granulosus casein kinase I delta 0.0054 0.0217 0.0217
Schistosoma mansoni cercarial elastase (S01 family) 0.0341 0.1714 0.1708
Brugia malayi TAR-binding protein 0.0069 0.0292 0.0285
Schistosoma mansoni smad 0.0016 0.0016 0.0009
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.014 0.0459
Onchocerca volvulus 0.0047 0.0179 0.0851
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0036 0.0036
Leishmania major hypothetical protein, conserved 0.0025 0.0067 0.011
Brugia malayi F/Y-rich N-terminus family protein 0.0017 0.0025 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0421 0.2134 0.2127
Toxoplasma gondii histone lysine methyltransferase SET1 0.0111 0.0516 0.226
Schistosoma mansoni hypothetical protein 0.0333 0.1675 0.1668
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0184 0.0896 0.4078
Echinococcus granulosus muscleblind protein 0.0608 0.3107 0.3107
Echinococcus multilocularis cyclin dependent kinase 1 0.0421 0.2134 0.2134
Loa Loa (eye worm) hypothetical protein 0.0036 0.0122 0.0122
Schistosoma mansoni cercarial elastase (S01 family) 0.0341 0.1714 0.1708
Brugia malayi Trypsin family protein 0.0341 0.1714 0.1708
Schistosoma mansoni thyroid hormone receptor 0.002 0.0036 0.0029
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0431 0.0424
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0061 0.0254 0.1005
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0341 0.1714 0.1708
Onchocerca volvulus 0.0341 0.1714 1
Loa Loa (eye worm) RNA binding protein 0.0069 0.0292 0.0292
Echinococcus granulosus casein kinase I alpha 0.0054 0.0217 0.0217
Schistosoma mansoni patched 1 0.0041 0.0147 0.0139
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.0257 0.0257
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.014 0.0459
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0178 0.0866 0.3934
Echinococcus granulosus snurportin 1 0.0305 0.1527 0.1527
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0158 0.0548
Schistosoma mansoni hypothetical protein 0.0305 0.1527 0.152
Trichomonas vaginalis ran, putative 0.0021 0.0044 0.0199
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0036 0.0029
Plasmodium falciparum protein kinase 5 0.0421 0.2134 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0331 0.1662 0.7765
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0054 0.0217 0.0217
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0122 0.0114
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0098 0.0444 0.0444
Leishmania major casein kinase, putative 0.0054 0.0217 0.0827
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0054 0.0217 0.0217
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0438 0.0431
Onchocerca volvulus 0.0341 0.1714 1
Echinococcus granulosus sulfhydryl oxidase 1 0.0028 0.0082 0.0082
Giardia lamblia Kinase, CMGC CDK 0.0421 0.2134 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.014 0.0459
Onchocerca volvulus 0.0054 0.0217 0.1074
Echinococcus granulosus rho-associated protein kinase 1 0.018 0.0876 0.0876
Brugia malayi casein kinase 1, delta 0.0054 0.0217 0.0209
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0036
Loa Loa (eye worm) acetyltransferase 0.0146 0.0697 0.0697
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0254 0.1184
Brugia malayi casein kinase I 0.0054 0.0217 0.0209
Schistosoma mansoni cercarial elastase (S01 family) 0.0341 0.1714 0.1708
Schistosoma mansoni serine/threonine protein kinase 0.0421 0.2134 0.2127
Echinococcus multilocularis tar DNA binding protein 0.0069 0.0292 0.0292
Toxoplasma gondii hypothetical protein 0.0053 0.0213 0.0808
Entamoeba histolytica hypothetical protein 0.0105 0.0483 0.2104
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0421 0.2134 1
Mycobacterium ulcerans hypothetical protein 0.0174 0.0844 0.4535
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0026 0.0026
Loa Loa (eye worm) Smad1 0.0016 0.0016 0.0016
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0098 0.0444 0.0437
Brugia malayi Trypsin family protein 0.0341 0.1714 0.1708
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0036 0.0036
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0028 0.0082 0.0082
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0178 0.0866 0.3934
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0105 0.0483 0.0483
Echinococcus granulosus microtubule associated protein 2 0.1558 0.8073 0.8073
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0177 0.072
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0697 0.069
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0129 0.041
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0122 0.046
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0036
Trypanosoma brucei cdc2-related kinase 3 0.0421 0.2134 1
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0341 0.1714 0.1714
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0158 0.0548
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0341 0.1714 0.1714
Schistosoma mansoni hypothetical protein 0.0134 0.0632 0.0625
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0082 0.0183
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0054 0.0217 0.0827
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0129 0.0494
Schistosoma mansoni cercarial elastase (S01 family) 0.0341 0.1714 0.1708
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0292 0.0285
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0129 0.041
Schistosoma mansoni carbonic anhydrase 0.0087 0.0386 0.0378
Loa Loa (eye worm) hypothetical protein 0.0341 0.1714 0.1714
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0129 0.0129
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0129 0.041
Trypanosoma cruzi casein kinase, putative 0.0054 0.0217 0.0827
Onchocerca volvulus 0.0042 0.0153 0.0699
Entamoeba histolytica protein kinase, putative 0.0054 0.0217 0.0828
Loa Loa (eye worm) hypothetical protein 0.0341 0.1714 0.1714
Brugia malayi Muscleblind-like protein 0.0608 0.3107 0.3102
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0036 0.0029
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0067 0.011
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0292 0.0285
Loa Loa (eye worm) hypothetical protein 0.0341 0.1714 0.1714
Echinococcus granulosus Mastin 0.0341 0.1714 0.1714
Entamoeba histolytica casein kinase, putative 0.0054 0.0217 0.0827
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0122 0.0567
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0016 0.0016
Echinococcus multilocularis glycoprotein Antigen 5 0.0341 0.1714 0.1714
Echinococcus multilocularis geminin 0.0333 0.1675 0.1675
Trypanosoma brucei protein kinase, putative 0.0061 0.0254 0.1084
Echinococcus multilocularis smad 0.0016 0.0016 0.0016
Brugia malayi beta-lactamase family protein 0.0036 0.0122 0.0115
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0039 0.0139 0.0132
Schistosoma mansoni microtubule-associated protein tau 0.1558 0.8073 0.8072
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0305 0.1527 0.1527
Echinococcus multilocularis casein kinase I delta 0.0054 0.0217 0.0217
Leishmania major carbonic anhydrase-like protein 0.0184 0.0896 0.4078
Schistosoma mansoni hypothetical protein 0.0087 0.0386 0.0378
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0036 0.0029
Loa Loa (eye worm) hypothetical protein 0.023 0.1136 0.1136
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0122 0.0122
Echinococcus multilocularis expressed conserved protein 0.0089 0.04 0.04
Echinococcus multilocularis enteropeptidase 0.0341 0.1714 0.1714
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0036 0.0029
Loa Loa (eye worm) hypothetical protein 0.0095 0.0431 0.0431
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1927 1 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0174 0.0844 0.7118
Plasmodium vivax protein kinase Crk2 0.0421 0.2134 1
Trypanosoma brucei quiescin sulfhydryl oxidase 0.0028 0.0082 0.027
Echinococcus granulosus survival motor neuron protein 1 0.023 0.1136 0.1136
Onchocerca volvulus 0.0341 0.1714 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0341 0.1714 0.1708
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0083 0.0189
Onchocerca volvulus 0.0036 0.0122 0.0512
Loa Loa (eye worm) hypothetical protein 0.0025 0.0067 0.0067
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0254 0.1184
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0036 0.0036
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0184 0.0896 0.0889
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0016 0.0016
Brugia malayi MH2 domain containing protein 0.0232 0.1143 0.1137
Loa Loa (eye worm) hypothetical protein 0.0029 0.0083 0.0083
Schistosoma mansoni intermediate filament proteins 0.0026 0.0071 0.0063
Trypanosoma cruzi casein kinase, putative 0.0054 0.0217 0.0827
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0036 0.0029
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0257 0.025
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0122 0.0375
Entamoeba histolytica casein kinase 1, putative 0.0054 0.0217 0.0827
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0036 0.0029
Loa Loa (eye worm) hypothetical protein 0.0341 0.1714 0.1714
Schistosoma mansoni hypothetical protein 0.0341 0.1714 0.1708
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0196 0.0955 0.0949
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0036 0.0029
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0098 0.0444 0.1985
Giardia lamblia Kinase, CK1 Casein kinase 0.0054 0.0217 0.0827
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0674 0.0666
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0217 0.0209
Echinococcus multilocularis muscleblind protein 0.0608 0.3107 0.3107
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0674 0.0674
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0257 0.025
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0122 0.0567
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0067 0.011
Toxoplasma gondii exonuclease III APE 0.0037 0.0129 0.041
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0044 0.0088
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0129 0.041
Loa Loa (eye worm) TAR-binding protein 0.0069 0.0292 0.0292
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0071 0.0071
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0061 0.0254 0.1005
Echinococcus granulosus expressed conserved protein 0.0089 0.04 0.04
Schistosoma mansoni ran 0.0021 0.0044 0.0036
Loa Loa (eye worm) hypothetical protein 0.0036 0.0122 0.0122
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0421 0.2134 0.2134
Toxoplasma gondii casein kinase I 0.0054 0.0217 0.0827
Giardia lamblia Kinase, STE STE20 0.0098 0.0444 0.1913
Trichomonas vaginalis STE family protein kinase 0.0098 0.0444 0.2074
Trypanosoma cruzi casein kinase, putative 0.0054 0.0217 0.0827
Entamoeba histolytica hypothetical protein 0.0105 0.0483 0.2104
Echinococcus granulosus GPCR family 2 0.0062 0.0257 0.0257
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0061 0.0254 0.1005
Schistosoma mansoni cpg binding protein 0.006 0.0248 0.0241
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0036 0.0029
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0331 0.1662 0.7745
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0036 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0421 0.2134 1
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0036 0.0036
Echinococcus multilocularis carbonic anhydrase II 0.0184 0.0896 0.0896
Brugia malayi MH1 domain containing protein 0.0016 0.0016 0.0009
Echinococcus multilocularis carbonic anhydrase 0.0087 0.0386 0.0386
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.023 0.0892
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0178 0.0866 0.3934
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0083 0.0275
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0054 0.0217 0.0217
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0055 0.0251
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0039 0.0139 0.0132
Echinococcus multilocularis mitogen activated protein kinase 0.0061 0.0254 0.0254

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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