Detailed information for compound 589672

Basic information

Technical information
  • TDR Targets ID: 589672
  • Name: 4-chloro-3-nitro-benzoic acid
  • MW: 201.564 | Formula: C7H4ClNO4
  • H donors: 1 H acceptors: 4 LogP: 1.91 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1cc(ccc1Cl)C(=O)O
  • InChi: 1S/C7H4ClNO4/c8-5-2-1-4(7(10)11)3-6(5)9(12)13/h1-3H,(H,10,11)
  • InChiKey: DFXQXFGFOLXAPO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-chloro-3-nitrobenzoic acid
  • 96-99-1
  • 4-09-00-01226 (Beilstein Handbook Reference)
  • BRN 0783626
  • CCRIS 3126
  • EINECS 202-550-9
  • 3-Nitro-4-chlorobenzoic acid
  • Benzoic acid, 4-chloro-3-nitro-
  • Kyselina 4-chloro-3-nitrobenzoova
  • NSC8440
  • WLN: WNR BG EVQ
  • SBB000404
  • InChI=1/C7H4ClNO4/c8-5-2-1-4(7(10)11)3-6(5)9(12)13/h1-3H,(H,10,11
  • NSC 8440
  • C60007_ALDRICH
  • 25450_FLUKA
  • Kyselina 4-chloro-3-nitrobenzoova [Czech]

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi beta-lactamase family protein 0.0035 0.0524 0.0526
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0524 0.012
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Loa Loa (eye worm) hypothetical protein 0.0043 0.0673 0.0632
Schistosoma mansoni ran 0.0023 0.0297 0.0289
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0066 0.1095 0.1815
Leishmania major hypothetical protein, conserved 0.0066 0.1095 0.1815
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0051 0.0043
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0673 0.0666
Schistosoma mansoni lamin 0.0056 0.092 0.0913
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0066 0.1095 0.1815
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.08 0.0832
Echinococcus granulosus geminin 0.0336 0.6163 0.616
Loa Loa (eye worm) hypothetical protein 0.0035 0.0524 0.0483
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0066 0.1095 0.1815
Loa Loa (eye worm) hypothetical protein 0.0066 0.1095 0.1056
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0066 0.1095 0.1161
Onchocerca volvulus Serine\/threonine kinase homolog 0.0295 0.5392 1
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0297 0.0289
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0065 0.1074 0.1773
Mycobacterium tuberculosis Conserved protein 0.0035 0.0524 0.012
Plasmodium vivax phosphodiesterase gamma, putative 0.0066 0.1095 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0066 0.1095 0.1815
Schistosoma mansoni inositol monophosphatase 0.0037 0.0553 0.0546
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.169 0.2735
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0188 0.0181
Brugia malayi Protein kinase domain containing protein 0.0093 0.1603 0.1724
Loa Loa (eye worm) hypothetical protein 0.0035 0.0524 0.0483
Schistosoma mansoni hypothetical protein 0.0015 0.0143 0.0135
Giardia lamblia Kinase, PLK 0.0295 0.5392 0.5251
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0051 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0295 0.5392 1
Plasmodium vivax importin-beta 2, putative 0.0032 0.0453 0.1955
Loa Loa (eye worm) hypothetical protein 0.0055 0.09 0.086
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Brugia malayi CHE-14 protein 0.0043 0.0673 0.0691
Leishmania major cAMP-specific phosphodiesterase, putative 0.0066 0.1095 0.1815
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.098 0.1595
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0066 0.1095 0.1089
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0175 0.0168
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0553 0.0503
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.092 0.088
Schistosoma mansoni tyrosine kinase 0.0156 0.2789 0.2784
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0051 0.0043
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.01 0.1736 0.1872
Trichomonas vaginalis CAMK family protein kinase 0.0295 0.5392 1
Plasmodium falciparum phosphodiesterase gamma, putative 0.0066 0.1095 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0051 0.0043
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0231 0.4205 0.42
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0066 0.1095 0.1089
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus granulosus insulin receptor 0.0093 0.1603 0.1596
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0474 0.8766 0.8765
Brugia malayi beta-lactamase family protein 0.0035 0.0524 0.0526
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0524 0.012
Brugia malayi PHD-finger family protein 0.0026 0.0353 0.0336
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0553 0.0116
Loa Loa (eye worm) inositol-1 0.0037 0.0553 0.0512
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0297 0.0293
Echinococcus granulosus GPCR family 2 0.0016 0.0157 0.0149
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0553 0.1026
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0524 0.012
Toxoplasma gondii ABC1 family protein 0.0035 0.0524 0.0234
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Loa Loa (eye worm) hypothetical protein 0.0016 0.0157 0.0114
Echinococcus multilocularis 0.009 0.1548 0.1542
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.08 0.0793
Schistosoma mansoni hypothetical protein 0.0016 0.0157 0.0149
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0553 0.0264
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0453 0.0161
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.054 1 1
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0066 0.1095 0.1161
Echinococcus multilocularis protein dispatched 1 0.0049 0.0788 0.078
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0336 0.6176 0.616
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0066 0.1095 0.1089
Echinococcus granulosus Niemann Pick C1 protein 0.0144 0.2564 0.2558
Trichomonas vaginalis CAMK family protein kinase 0.0295 0.5392 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0007
Leishmania major hypothetical protein, conserved 0.0066 0.1095 0.1815
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0157 0.0149
Schistosoma mansoni cpg binding protein 0.0035 0.0519 0.0512
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0795 0.0755
Schistosoma mansoni hypothetical protein 0.0042 0.0644 0.0636
Schistosoma mansoni tyrosine kinase 0.0093 0.1603 0.1596
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0524 0.0446
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0524 0.0446
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0157 0.0149
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0066 0.1095 0.2032
Loa Loa (eye worm) hypothetical protein 0.0026 0.0353 0.031
Schistosoma mansoni hypothetical protein 0.002 0.0241 0.0234
Loa Loa (eye worm) beta-lactamase 0.0035 0.0524 0.0483
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.4095 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.08 0.0793
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0553 0.0782
Echinococcus multilocularis snurportin 1 0.0336 0.6176 0.6173
Echinococcus multilocularis Niemann Pick C1 protein 0.0144 0.2564 0.2558
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Schistosoma mansoni hypothetical protein 0.0042 0.0644 0.0636
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0044 0.0036
Echinococcus granulosus epidermal growth factor receptor 0.029 0.5311 0.5307
Loa Loa (eye worm) hypothetical protein 0.005 0.0795 0.0755
Onchocerca volvulus 0.0056 0.092 0.1627
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0051 0.0043
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.1782 0.1775
Echinococcus multilocularis insulin receptor 0.0093 0.1603 0.1596
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.031 0.0302
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0066 0.1095 0.1089
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Brugia malayi Inositol-1 0.0037 0.0553 0.0558
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus granulosus survival motor neuron protein 1 0.049 0.9053 0.9052
Loa Loa (eye worm) hypothetical protein 0.0027 0.0372 0.033
Loa Loa (eye worm) TKL/LRRK protein kinase 0.006 0.0985 0.0945
Schistosoma mansoni zinc finger protein 0.0021 0.0255 0.0248
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0051 0.0043
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Onchocerca volvulus 0.0031 0.0451 0.0749
Schistosoma mansoni hypothetical protein 0.0016 0.0157 0.0149
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0156 0.2789 0.2784
Brugia malayi Dihydrofolate reductase 0.0169 0.3032 0.3311
Brugia malayi hypothetical protein 0.049 0.9053 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.1095 0.1056
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0341 0.0087
Schistosoma mansoni tyrosine kinase 0.0156 0.2789 0.2784
Loa Loa (eye worm) hypothetical protein 0.0035 0.0524 0.0483
Schistosoma mansoni bromodomain containing protein 0.0064 0.106 0.1053
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0066 0.1095 0.1815
Schistosoma mansoni thyroid hormone receptor 0.001 0.0051 0.0043
Echinococcus multilocularis survival motor neuron protein 1 0.049 0.9053 0.9052
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0175 0.0168
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0524 0.0517
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0051 0.0043
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0051 0.0043
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0066 0.1095 0.1089
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0428 0.0386
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0453 0.084
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0524 0.012
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0066 0.1095 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0553 0.0782
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0453 0.0446
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0066 0.1095 0.1089
Schistosoma mansoni hypothetical protein 0.0042 0.0644 0.0636
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0065 0.1074 0.0801
Loa Loa (eye worm) hypothetical protein 0.004 0.0611 0.057
Schistosoma mansoni cpg binding protein 0.0031 0.0451 0.0443
Schistosoma mansoni importin beta-1 0.0032 0.0453 0.0446
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0051 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0007
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0157 0.0149
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.098 0.0704
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0051 0.0043
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0341 0.0377
Schistosoma mansoni hypothetical protein 0.0336 0.6163 0.616
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.169 0.2735
Echinococcus multilocularis cpg binding protein 0.0035 0.0519 0.0512
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.08 0.0793
Schistosoma mansoni nuclear hormone receptor 0.001 0.0051 0.0043
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0524 0.0446
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0051 0.0043
Loa Loa (eye worm) TK/INSR protein kinase 0.0093 0.1603 0.1566
Brugia malayi serine/threonine-protein kinase plk-2 0.0295 0.5392 0.5933
Trypanosoma cruzi polo-like protein kinase, putative 0.0295 0.5392 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.068 0.0639
Loa Loa (eye worm) hypothetical protein 0.0066 0.1095 0.1056
Echinococcus multilocularis Niemann Pick C1 protein 0.0101 0.1752 0.1746
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0066 0.1095 0.2032
Loa Loa (eye worm) TK/EGFR protein kinase 0.029 0.5311 0.5291
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Schistosoma mansoni kinase 0.0428 0.7906 0.7904
Loa Loa (eye worm) hypothetical protein 0.0026 0.0353 0.031
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.098 0.1818
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.098 0.0973
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0066 0.1095 0.1089
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.08 0.0793
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0451 0.0409
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0066 0.1095 0.1161
Loa Loa (eye worm) hypothetical protein 0.0017 0.0188 0.0145
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0066 0.1095 0.1089
Echinococcus granulosus expressed conserved protein 0.0095 0.1638 0.1631
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0673 0.0738
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0175 0.0168
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.054 1 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.098 0.0973
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0076 0.0029
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0065 0.1074 0.1773
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0066 0.1095 0.1089
Echinococcus granulosus epidermal growth factor receptor 0.0156 0.2789 0.2784
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0157 0.0114
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.031 0.0302
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0093 0.1603 0.1596
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus multilocularis expressed conserved protein 0.0095 0.1638 0.1631
Entamoeba histolytica hypothetical protein 0.0026 0.0341 0.0087
Schistosoma mansoni survival motor neuron protein 0.01 0.1736 0.173
Echinococcus multilocularis epidermal growth factor receptor 0.0156 0.2789 0.2784
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0169 0.3032 0.7057
Brugia malayi beta-lactamase 0.0035 0.0524 0.0526
Schistosoma mansoni hypothetical protein 0.0336 0.6163 0.616
Trypanosoma cruzi polo-like protein kinase, putative 0.0295 0.5392 1
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.1095 0.1815
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0066 0.1095 0.1089
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.1095 0.1815
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0524 0.0446
Entamoeba histolytica serine/threonine protein kinase, putative 0.0295 0.5392 1
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0065 0.1074 0.9726
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0523 0.0515
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0297 0.0293
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0066 0.1095 0.1089
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0169 0.3032 1
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.054 1 1
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0066 0.1095 0.1161
Loa Loa (eye worm) hypothetical protein 0.049 0.9053 0.9049
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Schistosoma mansoni tyrosine kinase 0.029 0.5311 0.5307
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0065 0.1074 0.1991
Trichomonas vaginalis esterase, putative 0.0035 0.0524 0.0446
Brugia malayi Bromodomain containing protein 0.0075 0.1275 0.136
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0553 0.0503
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0051 0.0043
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0051 0.0043
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Loa Loa (eye worm) hypothetical protein 0.054 1 1
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0007
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0295 0.5392 0.5388
Trypanosoma brucei ISWI complex protein 0.0015 0.0143 0.0265
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0157 0.0118
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.08 0.0793
Schistosoma mansoni hypothetical protein 0.0034 0.05 0.0492
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0524 0.012
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0007
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0066 0.1095 0.1089
Echinococcus granulosus intermediate filament protein 0.0056 0.092 0.0913
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0524 0.0517
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0297 0.055
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0051 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0051 0.0007
Echinococcus multilocularis GPCR, family 2 0.0016 0.0157 0.0149
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0341 0.0087
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0524 0.0517
Schistosoma mansoni coup transcription factor 0.001 0.0051 0.0043
Echinococcus granulosus cpg binding protein 0.0035 0.0519 0.0512
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0295 0.5392 1
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0453 0.084
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0051 0.0043
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0474 0.8766 0.8761
Mycobacterium leprae Probable lipase LipE 0.0035 0.0524 0.017
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0524 0.0483
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.1111 0.1104
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.098 0.1818
Echinococcus granulosus Niemann Pick C1 protein 0.0101 0.1752 0.1746
Brugia malayi intermediate filament protein 0.0056 0.092 0.0965
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0066 0.1095 0.1815
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.006 0.0985 0.0978
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0341 0.0087
Loa Loa (eye worm) dihydrofolate reductase 0.0169 0.3032 0.3001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Loa Loa (eye worm) hypothetical protein 0.0101 0.1752 0.1716
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0428 0.042
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0051 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0295 0.5392 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0007
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0523 0.0515
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0553 0.0782
Loa Loa (eye worm) intermediate filament protein 0.0056 0.092 0.088
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0187 0.0144
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0051 0.0007
Echinococcus multilocularis musashi 0.0056 0.092 0.0913
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0295 0.5392 0.5372
Brugia malayi Niemann-Pick C1 protein precursor 0.0101 0.1752 0.189
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.08 0.0793
Schistosoma mansoni hypothetical protein 0.0016 0.0157 0.0149
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0066 0.1095 0.1161
Giardia lamblia hypothetical protein 0.0066 0.1095 0.0823
Echinococcus multilocularis zinc finger protein 0.0021 0.0255 0.0248
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.2032
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0051 0.0043
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0372 0.0365
Echinococcus multilocularis epidermal growth factor receptor 0.029 0.5311 0.5307
Schistosoma mansoni tyrosine kinase 0.0154 0.2759 0.2753
Schistosoma mansoni cpg binding protein 0.0035 0.0519 0.0512
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0188 0.0181
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0066 0.1095 0.1815
Brugia malayi Importin beta-1 subunit 0.0032 0.0453 0.0447
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.098 0.1818
Loa Loa (eye worm) hypothetical protein 0.0038 0.0568 0.0526
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.1095 0.1815
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.08 0.0793
Loa Loa (eye worm) hypothetical protein 0.0053 0.0855 0.0815
Giardia lamblia Hypothetical protein 0.0066 0.1095 0.0823
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0553 0.5
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.054 1 1
Schistosoma mansoni tyrosine kinase 0.0154 0.2759 0.2753
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0101 0.1752 0.2857
Loa Loa (eye worm) hypothetical protein 0.0035 0.0524 0.0483
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0066 0.1095 0.1089
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0066 0.1095 0.2032
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0553 0.0503
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Loa Loa (eye worm) hypothetical protein 0.0034 0.05 0.0458
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0066 0.1095 0.1089
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0169 0.3032 1
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0066 0.1095 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0295 0.5392 1
Schistosoma mansoni hypothetical protein 0.01 0.1736 0.173
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0524 0.0526
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0994 0.0987
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0066 0.1095 0.1089
Schistosoma mansoni lamin 0.0056 0.092 0.0913
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0066 0.1095 0.1056
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0066 0.1095 0.1089
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0524 0.2846
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.098 0.0973
Schistosoma mansoni tyrosine kinase 0.0154 0.2759 0.2753
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.098 0.1381
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0297 0.0289
Echinococcus granulosus zinc finger protein 0.0021 0.0255 0.0248
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0175 0.0168
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0066 0.1095 0.1815
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.05 0.0499
Loa Loa (eye worm) hypothetical protein 0.0032 0.0453 0.0411
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0474 0.8766 0.8765
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0524 0.0972
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0066 0.1095 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0673 0.0666
Schistosoma mansoni serine/threonine protein kinase 0.0295 0.5392 0.5388
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.006 0.0992 0.0985
Leishmania major hypothetical protein, conserved 0.0035 0.0524 0.0726
Schistosoma mansoni inositol monophosphatase 0.0037 0.0553 0.0546
Schistosoma mansoni hypothetical protein 0.0336 0.6176 0.6173
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.2032
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0066 0.1095 0.1089
Leishmania major GTP-binding protein, putative 0.0023 0.0297 0.0293
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.1021 0.0747
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0297 0.0273
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0524 0.0726
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0673 0.0666
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0297 0.0254
Echinococcus granulosus lamin dm0 0.0056 0.092 0.0913
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0051 0.0043
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0188 0.0181
Loa Loa (eye worm) PDE1B protein 0.0066 0.1095 0.1056
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0051 0.0007
Onchocerca volvulus 0.0035 0.0524 0.0886
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0093 0.1603 0.1596
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.1095 0.1568
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0524 0.0517
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.098 0.0973
Echinococcus granulosus importin subunit beta 1 0.0032 0.0453 0.0446
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0044 0.0036
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0795 0.0827
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0051 0.0007
Echinococcus multilocularis lamin 0.0056 0.092 0.0913
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0673 0.0632
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.1095 0.1815
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0065 0.1074 0.9726
Loa Loa (eye worm) hypothetical protein 0.0035 0.0524 0.0483
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0157 0.0118
Brugia malayi CXXC zinc finger family protein 0.0031 0.0451 0.0444
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0051 0.0043
Leishmania major importin beta-1 subunit, putative 0.0026 0.0341 0.0377
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0241 0.0198
Schistosoma mansoni patched 1 0.0043 0.0673 0.0666
Brugia malayi Furin-like cysteine rich region family protein 0.029 0.5311 0.5843
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0051 0.0043
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0066 0.1095 0.1815
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0066 0.1095 0.1089
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0553 0.0546
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0051 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0524 0.0726
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0051 0.0043
Mycobacterium tuberculosis Conserved protein 0.0035 0.0524 0.012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0051 0.0043
Brugia malayi RNA, U transporter 1 0.009 0.1544 0.1658
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0066 0.1095 0.1089
Echinococcus multilocularis geminin 0.0336 0.6163 0.616
Loa Loa (eye worm) hypothetical protein 0.0056 0.092 0.088
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0474 0.8766 0.9681
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0051 0.0043
Echinococcus granulosus FTZ F1 alpha 0.001 0.0051 0.0043
Schistosoma mansoni zinc finger protein 0.0015 0.0143 0.0135
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0553 0.0503
Onchocerca volvulus 0.0035 0.0524 0.0886
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0051 0.0043
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.08 0.0759
Brugia malayi Protein kinase domain containing protein 0.006 0.0985 0.1038
Trichomonas vaginalis CAMK family protein kinase 0.0295 0.5392 1
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.1095 0.1815
Trypanosoma brucei hypothetical protein, conserved 0.0066 0.1095 0.2032
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0524 0.012
Schistosoma mansoni ran 0.0023 0.0297 0.0289
Echinococcus granulosus dihydrofolate reductase 0.0169 0.3032 0.3026
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0066 0.1095 0.1089
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0066 0.1095 0.1089
Echinococcus multilocularis dihydrofolate reductase 0.0169 0.3032 0.3026
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0994 0.0987
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0051 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.1095 0.1568
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0051 0.0043
Echinococcus granulosus lamin 0.0056 0.092 0.0913
Schistosoma mansoni hypothetical protein 0.0016 0.0157 0.0149
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0372 0.0365
Plasmodium falciparum phosphodiesterase delta, putative 0.0066 0.1095 1
Onchocerca volvulus 0.0056 0.092 0.1627
Trichomonas vaginalis CAMK family protein kinase 0.0295 0.5392 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0524 0.0446
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0524 0.012
Brugia malayi dihydrofolate reductase family protein 0.0169 0.3032 0.3311
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0524 0.017
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 1
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.1095 0.1815
Trypanosoma brucei polo-like protein kinase 0.0295 0.5392 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Loa Loa (eye worm) hypothetical protein 0.0035 0.0524 0.0483
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0553 0.0546
Echinococcus multilocularis lamin dm0 0.0056 0.092 0.0913
Onchocerca volvulus 0.01 0.1736 0.3156
Mycobacterium tuberculosis Conserved protein 0.0035 0.0524 0.012
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0066 0.1095 0.1089
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0157 0.0149
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 1
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.092 0.0965
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.031 0.0302
Schistosoma mansoni thyroid hormone receptor 0.001 0.0051 0.0043
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0795 0.0827
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Plasmodium falciparum importin beta, putative 0.0032 0.0453 0.1955
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0051 0.0043
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.054 1 1
Schistosoma mansoni dihydrofolate reductase 0.0169 0.3032 0.3026
Echinococcus granulosus snurportin 1 0.0336 0.6176 0.6173
Schistosoma mansoni tyrosine kinase 0.0093 0.1603 0.1596
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Schistosoma mansoni hypothetical protein 0.0042 0.0644 0.0636
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0051 0.0043
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0231 0.4205 0.42
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0066 0.1095 0.2032
Loa Loa (eye worm) hypothetical protein 0.0069 0.1163 0.1124
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.054 1 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0295 0.5392 0.5388
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.1095 0.1568
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.1095 0.0823
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Onchocerca volvulus 0.0035 0.0524 0.0886
Echinococcus multilocularis protein patched 0.0043 0.0673 0.0666
Schistosoma mansoni intermediate filament proteins 0.0056 0.092 0.0913
Chlamydia trachomatis dihydrofolate reductase 0.0169 0.3032 0.5
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0066 0.1095 0.1568
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0051 0.0007
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.1095 0.1568
Brugia malayi Bromodomain containing protein 0.0038 0.0566 0.0573
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0188 0.0181

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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