Detailed information for compound 655458

Basic information

Technical information
  • TDR Targets ID: 655458
  • Name: 2-(5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-3 -yl)-N-(2,4-dimethylphenyl)acetamide
  • MW: 341.427 | Formula: C18H19N3O2S
  • H donors: 1 H acceptors: 2 LogP: 3.3 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(c(c1)C)NC(=O)Cn1cnc2c(c1=O)c(C)c(s2)C
  • InChi: 1S/C18H19N3O2S/c1-10-5-6-14(11(2)7-10)20-15(22)8-21-9-19-17-16(18(21)23)12(3)13(4)24-17/h5-7,9H,8H2,1-4H3,(H,20,22)
  • InChiKey: LQLJCVUZCITQDM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-(5,6-dimethyl-4-oxo-thieno[2,3-d]pyrimidin-3-yl)-N-(2,4-dimethylphenyl)acetamide
  • 2-(5,6-dimethyl-4-oxo-3-thieno[2,3-d]pyrimidinyl)-N-(2,4-dimethylphenyl)acetamide
  • N-(2,4-dimethylphenyl)-2-(4-keto-5,6-dimethyl-thieno[2,3-d]pyrimidin-3-yl)acetamide
  • 2-(5,6-dimethyl-4-oxo-thieno[2,3-d]pyrimidin-3-yl)-N-(2,4-dimethylphenyl)ethanamide
  • BAS 05171192
  • ZINC00132380
  • ST5021082
  • Oprea1_593233

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Brugia malayi hypothetical protein 0.0509 0.8802 1
Schistosoma mansoni jun-related protein 0.0078 0.1113 0.3813
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0983 1
Trypanosoma brucei heat shock protein, putative 0.0033 0.0305 0.0302
Onchocerca volvulus 0.0031 0.0266 0.0294
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0526 0.9107 0.9107
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0026 0.0184 0.0182
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0009 0.001
Echinococcus granulosus chromobox protein 1 0.0071 0.0983 0.3368
Loa Loa (eye worm) hypothetical protein 0.0104 0.1573 0.1787
Brugia malayi heat shock protein 90 0.0033 0.0305 0.0347
Schistosoma mansoni chromobox protein 0.0071 0.0983 0.3368
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.018 0.2919 0.331
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0018 0.0028 0.0032
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0305 0.5
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0008
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0526 0.9107 1
Trypanosoma cruzi Heat shock protein 83, putative 0.0033 0.0305 0.0302
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0184 0.1196
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0217 0.1551
Trypanosoma brucei heat shock protein, putative 0.0033 0.0305 0.0302
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Echinococcus multilocularis Protein lozenge 0.0064 0.0853 0.2921
Echinococcus granulosus cytochrome P450 2K1 0.0016 0.0003 0.001
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0526 0.9107 0.9107
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Loa Loa (eye worm) hypothetical protein 0.004 0.0425 0.0482
Echinococcus multilocularis heat shock protein 90 0.0033 0.0305 0.1045
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0032
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0026 0.0184 1
Loa Loa (eye worm) cytochrome P450 0.0016 0.0003 0.0003
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0003 0.0003
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Echinococcus multilocularis chromobox protein 1 0.0071 0.0983 0.3368
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Brugia malayi hypothetical protein 0.0018 0.0028 0.0032
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Schistosoma mansoni netrin receptor unc5 0.0017 0.0007 0.0025
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.001 0.0034
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0011
Toxoplasma gondii heat shock protein HSP90 0.0033 0.0305 1
Echinococcus granulosus sodium and chloride dependent glycine 0.0018 0.0028 0.0097
Plasmodium falciparum heat shock protein 90 0.0033 0.0305 1
Loa Loa (eye worm) hypothetical protein 0.0423 0.7269 0.8258
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Onchocerca volvulus 0.0104 0.1573 0.178
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0018 0.0028 0.0839
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0622 0.0706
Trypanosoma brucei heat shock protein, putative 0.0033 0.0305 0.0302
Mycobacterium ulcerans phytoene synthase, CrtB 0.018 0.2919 0.3203
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.018 0.2919 0.3203
Trypanosoma brucei heat shock protein, putative 0.0033 0.0305 0.0302
Trypanosoma cruzi squalene monooxygenase, putative 0.0191 0.3127 0.3125
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0425 0.3844
Brugia malayi Cytochrome P450 family protein 0.0016 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.018 0.2919 1
Echinococcus multilocularis Squalene phytoene synthase 0.018 0.2919 1
Trypanosoma brucei heat shock protein, putative 0.0033 0.0305 0.0302
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0425 0.0475
Schistosoma mansoni sodium/chloride dependent transporter 0.0018 0.0028 0.0097
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0007 0.0025
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0007 0.0025
Giardia lamblia Heat shock protein HSP 90-alpha 0.0033 0.0305 1
Brugia malayi Death domain containing protein 0.0017 0.0007 0.0008
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0018 0.0028 0.0097
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0305 0.0302
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0018 0.0028 0.0097
Schistosoma mansoni intermediate filament proteins 0.0031 0.0266 0.091
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0018 0.0028 0.0032
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0018 0.0028 0.0839
Plasmodium falciparum endoplasmin, putative 0.002 0.0076 0.1725
Schistosoma mansoni heat shock protein 0.0033 0.0305 0.1045
Echinococcus multilocularis lamin 0.0031 0.0266 0.091
Plasmodium vivax endoplasmin, putative 0.0033 0.0305 1
Loa Loa (eye worm) serotonin transporter b 0.0104 0.1573 0.1787
Echinococcus granulosus heat shock protein 90 0.0026 0.0184 0.0632
Echinococcus granulosus heat shock protein 90 0.0033 0.0305 0.1045
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0018 0.0028 0.0097
Leishmania major C-8 sterol isomerase-like protein 0.0423 0.7269 0.7268
Trypanosoma cruzi phytoene synthase, putative 0.018 0.2919 0.2917
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0007 0.0025
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0983 0.1117
Trypanosoma cruzi squalene monooxygenase, putative 0.0191 0.3127 0.3125
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0526 0.9107 1
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.0184 0.0182
Schistosoma mansoni endoplasmin 0.0033 0.0305 0.1045
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0097 0.1436 0.4919
Onchocerca volvulus 0.0018 0.0028 0.0024
Trypanosoma brucei heat shock protein, putative 0.0033 0.0305 0.0302
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0018 0.0028 0.0097
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0018 0.0028 0.0097
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0334 0.0379
Brugia malayi Endoplasmin precursor 0.0033 0.0305 0.0347
Trypanosoma brucei heat shock protein, putative 0.0033 0.0305 0.0302
Schistosoma mansoni sodium/chloride dependent transporter 0.0104 0.1573 0.539
Toxoplasma gondii hypothetical protein 0.0018 0.0028 0.0839
Loa Loa (eye worm) hypothetical protein 0.0104 0.1573 0.1787
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0479 0.0536
Echinococcus multilocularis chromobox protein 1 0.0071 0.0983 0.3368
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0305 0.0302
Echinococcus multilocularis sodium and chloride dependent glycine 0.0018 0.0028 0.0097
Onchocerca volvulus 0.0509 0.8802 1
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0062 0.0059
Mycobacterium ulcerans heat shock protein 90 0.0026 0.0184 0.0199
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0018 0.0028 0.0097
Brugia malayi intermediate filament protein 0.0031 0.0266 0.0302
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0104 0.1573 0.1787
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0018 0.0028 0.0097
Echinococcus granulosus geminin 0.0173 0.2803 0.9604
Schistosoma mansoni cytochrome P450 0.0016 0.0003 0.001
Onchocerca volvulus 0.0018 0.0028 0.0024
Loa Loa (eye worm) hypothetical protein 0.0509 0.8802 1
Leishmania major squalene monooxygenase-like protein 0.0191 0.3127 0.3125
Echinococcus multilocularis Ankyrin 0.0017 0.001 0.0034
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0305 0.0302
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Echinococcus granulosus Ankyrin 0.0017 0.001 0.0034
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0184 0.1196
Loa Loa (eye worm) hypothetical protein 0.0031 0.0271 0.0308
Echinococcus granulosus sodium and chloride dependent glycine 0.0018 0.0028 0.0097
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0423 0.7269 0.8258
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0007 0.0008
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0007 0.0025
Echinococcus multilocularis endoplasmin 0.0026 0.0184 0.0632
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0003 0.0003
Echinococcus multilocularis 0.0016 0.0003 0.001
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0305 0.0302
Loa Loa (eye worm) hypothetical protein 0.0035 0.0334 0.0379
Schistosoma mansoni lamin 0.0031 0.0266 0.091
Echinococcus multilocularis heat shock protein 0.0033 0.0305 0.1045
Echinococcus multilocularis serotonin transporter 0.0104 0.1573 0.539
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0526 0.9107 0.9107
Loa Loa (eye worm) endoplasmin 0.0033 0.0305 0.0347
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0018 0.0028 0.0097
Echinococcus granulosus jun protein 0.0097 0.1436 0.4919
Echinococcus multilocularis sodium and chloride dependent glycine 0.0018 0.0028 0.0097
Echinococcus granulosus lamin 0.0031 0.0266 0.091
Schistosoma mansoni hypothetical protein 0.0035 0.0334 0.1144
Trypanosoma brucei squalene monooxygenase, putative 0.0191 0.3127 0.3125
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0085 0.1224 0.4192
Trypanosoma cruzi squalene synthase, putative 0.0576 1 1
Schistosoma mansoni endoplasmin 0.0033 0.0305 0.1045
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0018 0.0028 0.0032
Toxoplasma gondii heat shock protein 90, putative 0.0033 0.0305 1
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Echinococcus multilocularis lamin dm0 0.0031 0.0266 0.091
Trypanosoma brucei Heat shock protein 83, putative 0.0033 0.0305 0.0302
Schistosoma mansoni hypothetical protein 0.0078 0.1113 0.3813
Brugia malayi Cytochrome P450 family protein 0.0016 0.0003 0.0003
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0018 0.0028 0.5
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Schistosoma mansoni lamin 0.0031 0.0266 0.091
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Plasmodium vivax heat shock protein 86, putative 0.0033 0.0305 1
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0305 0.0302
Echinococcus multilocularis jun protein 0.0097 0.1436 0.4919
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0032
Echinococcus granulosus nuclear factor of activated T cells 5 0.0085 0.1224 0.4192
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0032
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0018 0.0028 0.0032
Brugia malayi Cytochrome P450 family protein 0.0016 0.0003 0.0003
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0479 0.444
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0104 0.1573 0.539
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0032
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0018 0.0028 0.0097
Loa Loa (eye worm) hypothetical protein 0.0094 0.1388 0.1577
Onchocerca volvulus 0.0018 0.0028 0.0024
Loa Loa (eye worm) norepinephrine transporter 0.0104 0.1573 0.1787
Toxoplasma gondii hypothetical protein 0.0018 0.0028 0.0839
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0032
Schistosoma mansoni heat shock protein 0.0033 0.0305 0.1045
Echinococcus multilocularis geminin 0.0173 0.2803 0.9604
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0266 0.0302
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0184 0.1196
Trypanosoma cruzi squalene synthase, putative 0.0576 1 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0018 0.0028 0.0097
Loa Loa (eye worm) hypothetical protein 0.0104 0.1573 0.1787
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0266 0.0302
Schistosoma mansoni hypothetical protein 0.0017 0.0007 0.0025
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0018 0.0028 0.0097
Echinococcus granulosus Squalene phytoene synthase 0.018 0.2919 1
Onchocerca volvulus 0.0031 0.0271 0.03
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.018 0.2919 0.3316
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0216 0.3575 0.4061
Onchocerca volvulus 0.0076 0.1066 0.1203
Schistosoma mansoni chromobox protein 0.0071 0.0983 0.3368
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0479 0.444
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0425 0.3844
Trypanosoma cruzi heat shock protein 90, putative 0.0033 0.0305 0.0302
Brugia malayi chromobox protein homolog 3 0.004 0.0425 0.0482
Loa Loa (eye worm) hypothetical protein 0.0031 0.0266 0.0302
Trypanosoma brucei heat shock protein, putative 0.0033 0.0305 0.0302
Loa Loa (eye worm) solute carrier family 6 member 4 0.0104 0.1573 0.1787
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0009 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0217 0.1551
Loa Loa (eye worm) hypothetical protein 0.0509 0.8802 1
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.0184 0.0182
Trypanosoma brucei squalene synthase, putative 0.0576 1 1
Brugia malayi bZIP transcription factor family protein 0.0097 0.1436 0.1631
Echinococcus granulosus intermediate filament protein 0.0031 0.0266 0.091
Echinococcus granulosus heat shock protein 0.0033 0.0305 0.1045
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0266 0.0302
Echinococcus granulosus endoplasmin 0.0026 0.0184 0.0632
Brugia malayi Cytochrome P450 family protein 0.0016 0.0003 0.0003
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0026 0.0184 0.5
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0622 0.0706
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0097 0.1436 0.4919
Schistosoma mansoni hypothetical protein 0.0173 0.2803 0.9604
Loa Loa (eye worm) hypothetical protein 0.003 0.0256 0.029
Echinococcus multilocularis heat shock protein 90 0.0026 0.0184 0.0632
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0018 0.0028 0.0032
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0026 0.0184 0.0632
Loa Loa (eye worm) heat shock protein 90 0.0033 0.0305 0.0347
Loa Loa (eye worm) runx1 0.0064 0.0853 0.0969
Leishmania major heat shock protein 83-1 0.0033 0.0305 0.0302
Echinococcus granulosus serotonin transporter 0.0104 0.1573 0.539
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0018 0.0028 0.0839
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0423 0.7269 0.7268
Schistosoma mansoni sodium/chloride dependent transporter 0.0018 0.0028 0.0097
Brugia malayi Uncoordinated protein 44 0.0017 0.0007 0.0008
Echinococcus granulosus chromobox protein 1 0.0071 0.0983 0.3368
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0007 0.0025
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0051 0.0622 0.0706
Leishmania major hypothetical protein, conserved 0.018 0.2919 0.2917
Brugia malayi cytochrome P450 0.0016 0.0003 0.0003
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0305 0.5
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0173 0.2803 0.9604
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0018 0.0028 0.0032
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0622 0.0706
Brugia malayi hypothetical protein 0.0076 0.1066 0.1211
Brugia malayi Protein kinase domain containing protein 0.0017 0.0007 0.0008
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0018 0.0028 0.0097
Echinococcus granulosus death domain containing protein 0.0017 0.0007 0.0025
Schistosoma mansoni lozenge 0.0064 0.0853 0.2921
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0305 0.2526
Trypanosoma brucei C-8 sterol isomerase, putative 0.0423 0.7269 0.7268
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0526 0.9107 0.9107
Brugia malayi Heterochromatin protein 1 0.0071 0.0983 0.1117
Onchocerca volvulus 0.0031 0.0266 0.0294
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0018 0.0028 0.0097
Schistosoma mansoni hypothetical protein 0.0016 0.0003 0.001
Schistosoma mansoni sodium-dependent amino acid transporter 0.0018 0.0028 0.0097
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0983 1
Treponema pallidum sodium- and chloride- dependent transporter 0.0104 0.1573 1
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0018 0.0028 0.0097
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0018 0.0028 0.0097
Echinococcus multilocularis musashi 0.0031 0.0266 0.091
Echinococcus granulosus lamin dm0 0.0031 0.0266 0.091
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0026 0.0184 0.0199

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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