TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 228.27 | Formula: C12H8N2OS
H donors: 0 H acceptors: 2 LogP: 4.05 Rotable bonds: 1
Rule of 5 violations (Lipinski): 1
SMILES: [O-]c1c(sc2[n+]1cccc2)c1ccncc1
InChi: 1S/C12H8N2OS/c15-12-11(9-4-6-13-7-5-9)16-10-3-1-2-8-14(10)12/h1-8H
InChiKey: VOTNYVRLFSNDLN-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	neuropeptides capa receptor	0.0011	0.0098	0.0268
Leishmania major	p-glycoprotein	0.0132	0.288	0.3499
Giardia lamblia	Multidrug resistance-associated protein 1	0.0041	0.0795	1
Plasmodium falciparum	transporter, putative	0.001	0.0079	0.0079
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Echinococcus granulosus	fmrfamide receptor	0.0011	0.0098	0.0268
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0011	0.0098	0.012
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.0132	0.288	0.5493
Schistosoma mansoni	growth hormone secretagogue receptor	0.0011	0.0098	0.0268
Trichomonas vaginalis	sugar transporter, putative	0.0032	0.0588	0.1024
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0795	0.0966
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Trypanosoma cruzi	ABC transporter of the mitochondrion, putative	0.0041	0.0795	0.0762
Plasmodium vivax	ABC transporter B family member 3, putative	0.0041	0.0795	0.0721
Brugia malayi	G-protein coupled receptor	0.0011	0.0098	0.012
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0038	0.0721	0.0876
Echinococcus multilocularis	g protein coupled receptor	0.0011	0.0098	0.0268
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0011	0.0098	0.012
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Giardia lamblia	Multidrug resistance-associated protein 1	0.0041	0.0795	1
Echinococcus multilocularis	calcium dependent protein kinase	0.003	0.0533	0.1452
Onchocerca volvulus		0.0015	0.0182	0.0201
Echinococcus multilocularis	hyperpolarization activated cyclic	0.0009	0.0062	0.017
Schistosoma mansoni	sodium-dependent neurotransmitter transporter	0.001	0.0079	0.0216
Loa Loa (eye worm)	neuropeptide F receptor	0.0011	0.0098	0.012
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Brugia malayi	neuropeptide F receptor	0.0011	0.0098	0.012
Plasmodium vivax	multidrug resistance-associated protein 1, putative	0.0041	0.0795	0.0721
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.0132	0.288	0.5493
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0009	0.0062	0.017
Leishmania major	ATP-binding cassette protein subfamily B, member 3, putative	0.0041	0.0795	0.0966
Toxoplasma gondii	ABC transporter, putative	0.0041	0.0795	0.1204
Schistosoma mansoni	60S ribosomal protein L21	0.0008	0.0029	0.008
Onchocerca volvulus		0.0011	0.0098	0.0037
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0028	0.0495	0.1348
Entamoeba histolytica	ATP-binding cassette protein, putative	0.0041	0.0795	0.1661
Schistosoma mansoni	serine/threonine protein kinase	0.0032	0.0578	0.1576
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0011	0.0098	0.0268
Echinococcus multilocularis	ATP binding cassette sub family B	0.0041	0.0795	0.2167
Echinococcus granulosus	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Trypanosoma cruzi	hexose transporter, putative	0.0018	0.0251	0.0086
Loa Loa (eye worm)	solute carrier family 6 member 4	0.006	0.1222	0.1485
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Echinococcus multilocularis	g-protein coupled receptor	0.0011	0.0098	0.0268
Onchocerca volvulus		0.0011	0.0098	0.0037
Schistosoma mansoni	multidrug resistance protein	0.0132	0.288	0.7848
Mycobacterium ulcerans	drugs-transport transmembrane ATP-binding protein ABC transporter	0.0041	0.0795	1
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Leishmania major	pentamidine resistance protein 1	0.0041	0.0795	0.0966
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0032	0.0578	0.1576
Onchocerca volvulus		0.0232	0.5192	1
Brugia malayi	multidrug resistance related protein 1	0.0041	0.0795	0.0966
Onchocerca volvulus	Putative transporter	0.0015	0.0182	0.0201
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase)	0.002	0.0299	0.0434
Schistosoma mansoni	nuclear transcription factor X-box binding 1 (nfx1)	0.0015	0.0182	0.0496
Plasmodium vivax	CDK-related protein kinase 6, putative	0.0441	1	1
Mycobacterium ulcerans	transmembrane ABC transporter ATP-binding protein	0.0041	0.0795	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0011	0.0098	0.0268
Entamoeba histolytica	P-glycoprotein 5, putative	0.0132	0.288	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0011	0.0098	0.0268
Leishmania major	ATP-binding cassette protein subfamily B, member 1, putative	0.0041	0.0795	0.0966
Toxoplasma gondii	calcium-dependent protein kinase CDPK2A	0.0032	0.0579	0.0876
Loa Loa (eye worm)	hypothetical protein	0.001	0.0079	0.0097
Trichomonas vaginalis	sugar transport protein, putative	0.0015	0.0182	0.0233
Echinococcus granulosus	ATP binding cassette sub family B	0.004	0.0762	0.2076
Mycobacterium leprae	Probable prolyl tRNA synthetase ProS	0.0031	0.0564	0.5328
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Brugia malayi	ABC transporter family protein	0.0041	0.0795	0.0966
Echinococcus multilocularis		0.0041	0.0795	0.2167
Onchocerca volvulus		0.0011	0.0098	0.0037
Echinococcus granulosus	hyperpolarization activated cyclic	0.0009	0.0062	0.017
Toxoplasma gondii	hypothetical protein	0.0082	0.1728	0.2616
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Loa Loa (eye worm)	hypothetical protein	0.001	0.0079	0.0097
Leishmania major	ABC-thiol transporter	0.0041	0.0795	0.0966
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.0031	0.0564	0.1535
Plasmodium vivax	ABC transporter B family member 7, putative	0.0041	0.0795	0.0721
Loa Loa (eye worm)	ABC transporter	0.0041	0.0795	0.0966
Plasmodium vivax	calcium-dependent protein kinase, putative	0.0032	0.0579	0.0503
Schistosoma mansoni	voltage-gated potassium channel	0.0009	0.0062	0.017
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0011	0.0098	0.0268
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.001	0.0079	0.0097
Echinococcus multilocularis	solute carrier family 22	0.0015	0.0182	0.0496
Echinococcus granulosus	multidrug resistance associated protein 7	0.0041	0.0795	0.2167
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Echinococcus multilocularis	neuropeptides capa receptor	0.0011	0.0098	0.0268
Echinococcus granulosus	g protein coupled receptor	0.0011	0.0098	0.0268
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.0132	0.288	0.5493
Schistosoma mansoni	biogenic amine receptor	0.0011	0.0098	0.0268
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0011	0.0098	0.0268
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0032	0.0578	0.1576
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0036	0.0682	0.0829
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.0041	0.0795	0.1204
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0032	0.0588	0.0504
Onchocerca volvulus		0.0011	0.0098	0.0037
Toxoplasma gondii	cell-cycle-associated protein kinase MAPK, putative	0.0168	0.3712	0.5619
Mycobacterium leprae	PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER	0.0041	0.0795	1
Echinococcus granulosus	Sugar transporter ERD6 protein	0.0015	0.0182	0.0496
Schistosoma mansoni	voltage-gated potassium channel	0.0013	0.0138	0.0376
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Schistosoma mansoni	lysyl-tRNA synthetase	0.0023	0.038	0.1035
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.0132	0.288	0.7848
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Brugia malayi	Major Facilitator Superfamily protein	0.0015	0.0182	0.0221
Mycobacterium ulcerans	component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD	0.0041	0.0795	1
Echinococcus granulosus	serotonin transporter	0.006	0.1222	0.3331
Echinococcus multilocularis	neuropeptide receptor A26	0.0011	0.0098	0.0268
Brugia malayi	G protein-coupled receptor	0.0011	0.0098	0.012
Loa Loa (eye worm)	hypothetical protein	0.004	0.0762	0.0926
Echinococcus multilocularis	cyclic nucleotide gated cation channel	0.0009	0.0062	0.017
Plasmodium falciparum	ABC transporter B family member 5, putative	0.0041	0.0795	0.0795
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0009	0.0062	0.017
Brugia malayi	Dopamine receptor	0.0011	0.0098	0.012
Loa Loa (eye worm)	hypothetical protein	0.0132	0.2872	0.3489
Loa Loa (eye worm)	hypothetical protein	0.0365	0.8232	1
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Trypanosoma brucei	calcium/calmodulin-dependent protein kinase, putative	0.0032	0.0578	0.0492
Echinococcus granulosus	7TM GPCR rhodopsin	0.0011	0.0098	0.0268
Brugia malayi	hypothetical protein	0.0011	0.0098	0.012
Giardia lamblia	Prolyl-tRNA synthetase	0.0031	0.0564	0.6221
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Brugia malayi	putative neuropeptide receptor	0.0011	0.0098	0.012
Echinococcus granulosus	g-protein coupled receptor	0.0011	0.0098	0.0268
Schistosoma mansoni	multidrug resistance protein	0.0132	0.288	0.7848
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Toxoplasma gondii	prolyl-tRNA synthetase (ProRS)	0.0036	0.0682	0.1033
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Plasmodium vivax	proline--tRNA ligase, putative	0.0036	0.0682	0.0608
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0182	0.0233
Brugia malayi	Major Facilitator Superfamily protein	0.0015	0.0182	0.0221
Onchocerca volvulus		0.0015	0.0182	0.0201
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.0092	0.1964	0.3707
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.0132	0.288	0.7848
Brugia malayi	hypothetical protein	0.0011	0.0098	0.012
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.0132	0.288	0.5493
Schistosoma mansoni	opsin-like receptor	0.0011	0.0098	0.0268
Echinococcus multilocularis	sodium dependent neurotransmitter transporter	0.001	0.0079	0.0216
Schistosoma mansoni	multidrug resistance protein	0.0041	0.0795	0.2167
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0182	0.0233
Loa Loa (eye worm)	hypothetical protein	0.0029	0.052	0.0631
Plasmodium vivax	ABC transporter B family member 5, putative	0.0041	0.0795	0.0721
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0011	0.0098	0.0268
Brugia malayi	ABC transporter	0.004	0.0762	0.0926
Entamoeba histolytica	P-glycoprotein-1	0.0132	0.288	1
Echinococcus multilocularis	neuropeptide Y receptor	0.0011	0.0098	0.0268
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.0031	0.0564	0.1535
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Plasmodium falciparum	calcium-dependent protein kinase 2	0.0032	0.0579	0.0579
Plasmodium vivax	lysine--tRNA ligase, putative	0.0023	0.038	0.0303
Plasmodium falciparum	ABC transporter B family member 7, putative	0.0041	0.0795	0.0795
Loa Loa (eye worm)	inward rectifying k channel family protein 1	0.0082	0.1728	0.2099
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0062	0.0076
Brugia malayi	hypothetical protein	0.0011	0.0098	0.012
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0588	0.0504
Onchocerca volvulus		0.0015	0.0182	0.0201
Toxoplasma gondii	sugar transporter ST1	0.0015	0.0182	0.0276
Brugia malayi	Pre-SET motif family protein	0.0029	0.052	0.0631
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0029	0.052	0.1415
Plasmodium falciparum	multidrug resistance-associated protein 2	0.0041	0.0795	0.0795
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0029	0.052	0.1415
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0011	0.0098	0.0268
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0011	0.0098	0.0268
Leishmania major	p-glycoprotein e	0.0041	0.0795	0.0966
Toxoplasma gondii	Sodium:neurotransmitter symporter family protein	0.001	0.0079	0.012
Trypanosoma cruzi	C-8 sterol isomerase, putative	0.0365	0.8232	1
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0588	0.0504
Trichomonas vaginalis	abcb9, putative	0.0132	0.288	0.5493
Brugia malayi	Cyclic-nucleotide gated cation channel	0.0009	0.0062	0.0076
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0239	0.5337	0.6483
Schistosoma mansoni	voltage-gated potassium channel	0.0041	0.0797	0.2171
Echinococcus granulosus	serotonin receptor	0.0011	0.0098	0.0268
Schistosoma mansoni	neuropeptide receptor	0.0011	0.0098	0.0268
Mycobacterium ulcerans	sugar transporter	0.0015	0.0182	0.1191
Mycobacterium ulcerans	transmembrane ABC transporter ATP-binding protein	0.0041	0.0795	1
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0182	0.0233
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Schistosoma mansoni	histamine h1 receptor	0.0011	0.0098	0.0268
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Echinococcus multilocularis	neuropeptide s receptor	0.0011	0.0098	0.0268
Leishmania major	glucose transporter, lmgt2	0.0032	0.0588	0.0714
Schistosoma mansoni	protein kinase	0.0032	0.0578	0.1576
Trichomonas vaginalis	ABC transporter, putative	0.0132	0.288	0.5493
Chlamydia trachomatis	proline--tRNA ligase	0.0011	0.0099	0.0071
Schistosoma mansoni	myosin xvIII	0.0011	0.0098	0.0268
Echinococcus multilocularis	voltage gated potassium channel	0.0013	0.0138	0.0376
Schistosoma mansoni	adenoreceptor	0.0011	0.0098	0.0268
Schistosoma mansoni	neuropeptide F-like receptor	0.0011	0.0098	0.0268
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0032	0.0578	0.1576
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.0132	0.288	0.7848
Echinococcus granulosus	sodium:chloride dependent neurotransmitter	0.001	0.0079	0.0216
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Plasmodium falciparum	lysine--tRNA ligase	0.0023	0.038	0.038
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0011	0.0098	0.0268
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Toxoplasma gondii	hypothetical protein	0.001	0.0079	0.012
Onchocerca volvulus		0.0011	0.0098	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Trypanosoma brucei	lysyl-tRNA synthetase, putative	0.0023	0.038	0.0245
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0011	0.0098	0.0268
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.0132	0.288	0.7848
Onchocerca volvulus		0.0015	0.0182	0.0201
Loa Loa (eye worm)	hypothetical protein	0.001	0.0079	0.0097
Echinococcus granulosus	solute carrier family 22	0.0015	0.0182	0.0496
Echinococcus granulosus	neuropeptide FF receptor 2	0.0011	0.0098	0.0268
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.006	0.1222	0.1485
Schistosoma mansoni	hypothetical protein	0.0104	0.2238	0.6098
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.001	0.0079	0.0216
Echinococcus granulosus	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0104	0.2238	0.6098
Treponema pallidum	sodium- and chloride- dependent transporter	0.006	0.1222	1
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Echinococcus multilocularis	multidrug resistance protein 1	0.0092	0.1964	0.5351
Echinococcus multilocularis	serotonin transporter	0.006	0.1222	0.3331
Brugia malayi	lysyl-tRNA synthetase	0.0023	0.038	0.0461
Trichomonas vaginalis	glucose transporter, putative	0.0032	0.0588	0.1024
Onchocerca volvulus		0.0015	0.0182	0.0201
Schistosoma mansoni	amine GPCR	0.0011	0.0098	0.0268
Onchocerca volvulus		0.0015	0.0182	0.0201
Echinococcus granulosus	solute carrier family 22	0.0015	0.0182	0.0496
Echinococcus multilocularis	potassium:sodium hyperpolarization activated	0.0009	0.0062	0.017
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0011	0.0098	0.0268
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0013	0.0138	0.0376
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Schistosoma mansoni	sugar transporter	0.0015	0.0182	0.0496
Schistosoma mansoni	lysyl-tRNA synthetase	0.0023	0.038	0.1035
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0011	0.0098	0.0037
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0011	0.0098	0.012
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.0132	0.288	0.5493
Onchocerca volvulus		0.0015	0.0182	0.0201
Trypanosoma cruzi	hexose transporter	0.0032	0.0588	0.0504
Toxoplasma gondii	Sodium:neurotransmitter symporter family protein	0.001	0.0079	0.012
Echinococcus granulosus	g protein coupled receptor	0.0011	0.0098	0.0268
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Echinococcus multilocularis	somatostatin receptor	0.0011	0.0098	0.0268
Echinococcus multilocularis	allatostatin A receptor	0.0011	0.0098	0.0268
Schistosoma mansoni	neuropeptide receptor	0.0011	0.0098	0.0268
Leishmania major	hypothetical protein, conserved	0.0015	0.0182	0.0221
Echinococcus granulosus	neuropeptide receptor	0.0011	0.0098	0.0268
Brugia malayi	hypothetical protein	0.0041	0.0795	0.0966
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0132	0.2872	0.7824
Onchocerca volvulus		0.0015	0.0182	0.0201
Giardia lamblia	MRP-like ABC transporter	0.0041	0.0795	1
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0015	0.0182	0.0221
Plasmodium vivax	ABC transporter B family member 4, putative	0.0041	0.0795	0.0721
Brugia malayi	ABC transporter transmembrane region family protein	0.0041	0.0795	0.0966
Toxoplasma gondii	ABC transporter family protein	0.0041	0.0795	0.1204
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Trichomonas vaginalis	conserved hypothetical protein	0.0104	0.2238	0.4241
Trichomonas vaginalis	CAMK family protein kinase	0.0032	0.0578	0.1006
Echinococcus granulosus	tm gpcr rhodopsin	0.0011	0.0098	0.0268
Trichomonas vaginalis	ABC transporter, half transporter, putative	0.0132	0.288	0.5493
Wolbachia endosymbiont of Brugia malayi	ABC-type multidrug transport system, ATPase and permease component	0.0041	0.0795	1
Schistosoma mansoni	biogenic amine receptor	0.0011	0.0098	0.0268
Plasmodium falciparum	proline--tRNA ligase	0.0036	0.0682	0.0682
Echinococcus granulosus	synaptic vesicle 2 protein	0.0015	0.0182	0.0496
Schistosoma mansoni	amine GPCR	0.0011	0.0098	0.0268
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0011	0.0098	0.0268
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Echinococcus granulosus	lysyl tRNA synthetase	0.0023	0.038	0.1035
Echinococcus multilocularis	fmrfamide receptor	0.0011	0.0098	0.0268
Trypanosoma cruzi	multidrug resistance protein E, putative	0.0041	0.0795	0.0762
Echinococcus granulosus	multidrug resistance protein 1	0.0092	0.1964	0.5351
Entamoeba histolytica	P-glycoprotein-2, putative	0.004	0.0762	0.1529
Trypanosoma brucei	ABC transporter of the mitochondrion, putative	0.0041	0.0795	0.0762
Schistosoma mansoni	sugar transporter	0.0015	0.0182	0.0496
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Leishmania major	calcium channel protein, putative,ion transporter, putative	0.0039	0.0735	0.0893
Entamoeba histolytica	protein kinase, putative	0.0032	0.0578	0.0794
Brugia malayi	hypothetical protein	0.0011	0.0098	0.012
Echinococcus granulosus	potassium:sodium hyperpolarization activated	0.0009	0.0062	0.017
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0029	0.052	0.1415
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.004	0.0762	0.1364
Loa Loa (eye worm)	norepinephrine transporter	0.006	0.1222	0.1485
Brugia malayi	ABC transporter transmembrane region family protein	0.004	0.0762	0.0926
Mycobacterium ulcerans	sugar-transport integral membrane protein SugI	0.0015	0.0182	0.1191
Onchocerca volvulus		0.0015	0.0182	0.0201
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0588	0.0504
Plasmodium falciparum	ABC transporter B family member 6, putative	0.0041	0.0795	0.0795
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0588	0.0504
Brugia malayi	neuropeptide F receptor	0.0011	0.0098	0.012
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Schistosoma mansoni	neuropeptide receptor	0.0011	0.0098	0.0268
Brugia malayi	G protein-coupled receptor F59B2.13	0.0011	0.0098	0.012
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0011	0.0098	0.012
Giardia lamblia	ABC transporter, putative	0.0041	0.0795	1
Brugia malayi	multidrug resistance protein 3	0.0132	0.288	0.3499
Echinococcus granulosus	orexin receptor type 2	0.0011	0.0098	0.0268
Loa Loa (eye worm)	sugar transporter	0.0104	0.2238	0.2719
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0032	0.0578	0.1576
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.0132	0.288	0.5493
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Brugia malayi	hypothetical protein	0.001	0.0079	0.0097
Echinococcus granulosus	dro:myosuppressin receptor	0.0011	0.0098	0.0268
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Plasmodium vivax	ABC transporter B family member 6, putative	0.0041	0.0795	0.0721
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.006	0.1222	0.3331
Plasmodium falciparum	multidrug resistance protein 2	0.0041	0.0795	0.0795
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0032	0.0578	0.1576
Echinococcus granulosus	histone lysine methyltransferase setb	0.0029	0.052	0.1415
Mycobacterium leprae	Possible lysyl-tRNA synthetase 2 LysX	0.0023	0.038	0.1623
Onchocerca volvulus		0.0011	0.0098	0.0037
Plasmodium falciparum	hexose transporter	0.0104	0.2238	0.2238
Brugia malayi	GnHR receptor homolog	0.0011	0.0098	0.012
Echinococcus granulosus	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Echinococcus granulosus	multidrug resistance protein 1	0.0092	0.1964	0.5351
Echinococcus granulosus	geminin	0.0166	0.367	1
Echinococcus granulosus	neuropeptides capa receptor	0.0011	0.0098	0.0268
Echinococcus multilocularis	geminin	0.0166	0.367	1
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0613	0.0745
Schistosoma mansoni	multidrug resistance protein	0.004	0.0762	0.2076
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0104	0.2238	0.6098
Brugia malayi	Dopamine receptor protein 1	0.0011	0.0098	0.012
Brugia malayi	hypothetical protein	0.0011	0.0098	0.012
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0036	0.0682	0.0622
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0009	0.0062	0.017
Echinococcus granulosus	uncharacterized sodium dependent transporter	0.001	0.0079	0.0216
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Mycobacterium ulcerans	transmembrane ABC transporter ATP-binding protein	0.0041	0.0795	1
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0009	0.0062	0.017
Echinococcus multilocularis	ATP binding cassette sub family B	0.013	0.2847	0.7758
Plasmodium falciparum	multidrug resistance protein 1	0.0132	0.288	0.288
Loa Loa (eye worm)	bifunctional aminoacyl-tRNA synthetase	0.0013	0.014	0.0171
Schistosoma mansoni	sodium-dependent neurotransmitter transporter	0.001	0.0079	0.0216
Echinococcus multilocularis	sex peptide receptor	0.0011	0.0098	0.0268
Onchocerca volvulus		0.0011	0.0098	0.0037
Toxoplasma gondii	facilitative glucose transporter GT1	0.0104	0.2238	0.3389
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0013	0.0138	0.0376
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0011	0.0098	0.0268
Chlamydia trachomatis	lysine--tRNA ligase	0.0023	0.038	0.1072
Onchocerca volvulus		0.0015	0.0182	0.0201
Toxoplasma gondii	ATP-binding cassette transporter ABC.B1	0.0132	0.288	0.4361
Plasmodium vivax	SET domain protein, putative	0.0029	0.052	0.0444
Onchocerca volvulus		0.0011	0.0098	0.0037
Onchocerca volvulus		0.0015	0.0182	0.0201
Brugia malayi	hypothetical protein	0.0015	0.0182	0.0221
Entamoeba histolytica	ATP-binding cassette protein, putative	0.0041	0.0795	0.1661
Schistosoma mansoni	neuropeptide f receptor 76f	0.0011	0.0098	0.0268
Mycobacterium tuberculosis	Iron-regulated transporter IrtA	0.0041	0.0795	0.2272
Schistosoma mansoni	protein kinase	0.0032	0.0578	0.1576
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0033	0.0613	0.1074
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.0132	0.288	0.5493
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0029	0.052	0.0787
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Trypanosoma brucei	bifunctional aminoacyl-tRNA synthetase, putative	0.0036	0.0682	0.0622
Echinococcus multilocularis	multidrug resistance associated protein 7	0.0041	0.0795	0.2167
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0011	0.0098	0.0268
Brugia malayi	Major Facilitator Superfamily protein	0.0015	0.0182	0.0221
Trypanosoma cruzi	ABC transporter, mitochondrial, putative	0.0041	0.0795	0.0762
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.004	0.0762	0.1364
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Schistosoma mansoni	biogenic amine receptor	0.0011	0.0098	0.0268
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0011	0.0098	0.0268
Echinococcus multilocularis	glutamyl tRNA synthetase cytoplasmic	0.0031	0.0564	0.1535
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0011	0.0098	0.0268
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0204	0.4543	0.5519
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.002	0.0314	0.049
Brugia malayi	P-glycoprotein-like protein	0.0041	0.0795	0.0966
Echinococcus multilocularis	solute carrier family 22	0.0015	0.0182	0.0496
Toxoplasma gondii	calcium-dependent protein kinase CDPK3	0.0032	0.0579	0.0876
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Leishmania major	ATP-binding cassette protein subfamily C, member 2, putative	0.0041	0.0795	0.0966
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.001	0.0079	0.0216
Schistosoma mansoni	sodium-dependent neurotransmitter transporter	0.001	0.0079	0.0216
Schistosoma mansoni	hypothetical protein	0.0166	0.367	1
Brugia malayi	follicle stimulating hormone receptor	0.0239	0.5337	0.6483
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0588	0.0504
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.0132	0.288	0.7848
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.0132	0.288	0.5493
Plasmodium vivax	calcium-dependent protein kinase 1, putative	0.0032	0.0579	0.0503
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Loa Loa (eye worm)	calcium/calmodulin-dependent protein kinase ID	0.0032	0.0578	0.0703
Echinococcus multilocularis	ATP binding cassette sub family B	0.0041	0.0795	0.2167
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Schistosoma mansoni	glucose transport protein	0.0104	0.2238	0.6098
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Trichomonas vaginalis	conserved hypothetical protein	0.0032	0.0588	0.1024
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Schistosoma mansoni	multidrug resistance protein	0.0041	0.0795	0.2167
Loa Loa (eye worm)	G-protein coupled receptor	0.0011	0.0098	0.012
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0011	0.0098	0.0268
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Trypanosoma cruzi	hexose transporter, putative	0.0032	0.0588	0.0504
Echinococcus multilocularis	multidrug resistance protein 1	0.0132	0.288	0.7848
Brugia malayi	Pre-SET motif family protein	0.0204	0.4543	0.5519
Schistosoma mansoni	ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6)	0.004	0.0762	0.2076
Giardia lamblia	Lysyl-tRNA synthetase	0.0023	0.038	0.3223
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0182	0.0233
Echinococcus multilocularis	dro:myosuppressin receptor	0.0011	0.0098	0.0268
Loa Loa (eye worm)	multidrug resistance protein 3	0.0132	0.288	0.3499
Echinococcus multilocularis	cyclic nucleotide gated cation channel alpha 3	0.0009	0.0062	0.017
Echinococcus multilocularis	lysyl tRNA synthetase	0.0023	0.038	0.1035
Brugia malayi	Serotonin receptor	0.0011	0.0098	0.012
Loa Loa (eye worm)	hypothetical protein	0.013	0.2847	0.3459
Leishmania major	lysyl-tRNA synthetase, putative	0.0023	0.038	0.0461
Loa Loa (eye worm)	hypothetical protein	0.0186	0.4132	0.502
Loa Loa (eye worm)	serotonin transporter b	0.006	0.1222	0.1485
Brugia malayi	hypothetical protein	0.0011	0.0098	0.012
Brugia malayi	G-protein coupled receptor	0.0011	0.0098	0.012
Brugia malayi	hypothetical protein	0.0015	0.0182	0.0221
Brugia malayi	hypothetical protein	0.0011	0.0098	0.012
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0104	0.2238	0.6098
Echinococcus multilocularis	serotonin receptor	0.0132	0.2872	0.7824
Schistosoma mansoni	amine GPCR	0.0011	0.0098	0.0268
Trichomonas vaginalis	conserved hypothetical protein	0.0015	0.0182	0.0233
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0011	0.0098	0.012
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.0132	0.288	0.5493
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.0041	0.0795	0.1204
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0033	0.0613	0.1074
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0011	0.0098	0.0268
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.0132	0.288	0.5493
Entamoeba histolytica	hypothetical protein	0.0041	0.0795	0.1661
Plasmodium vivax	multidrug resistance protein 1, putative	0.0132	0.288	0.2823
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Loa Loa (eye worm)	hypothetical protein	0.001	0.0079	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0132	0.288	0.3499
Onchocerca volvulus		0.006	0.1222	0.2236
Loa Loa (eye worm)	neuropeptide F receptor	0.0011	0.0098	0.012
Brugia malayi	sulfakinin receptor protein	0.0011	0.0098	0.012
Trichomonas vaginalis	conserved hypothetical protein	0.0032	0.0588	0.1024
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0011	0.0098	0.0268
Entamoeba histolytica	P-glycoprotein-2	0.0132	0.288	1
Echinococcus multilocularis	sodium and chloride dependent glycine	0.001	0.0079	0.0216
Trichomonas vaginalis	abcb9, putative	0.0132	0.288	0.5493
Echinococcus multilocularis	neuropeptides capa receptor	0.0011	0.0098	0.0268
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type 1	0.0032	0.0578	0.1576
Echinococcus granulosus	neuropeptide Y receptor	0.0011	0.0098	0.0268
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0011	0.0098	0.0268
Plasmodium falciparum	calcium-dependent protein kinase 3	0.0032	0.0579	0.0579
Entamoeba histolytica	multidrug resistance protein, putative	0.0041	0.0795	0.1661
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0104	0.2238	0.6098
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0009	0.0062	0.017
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0011	0.0098	0.0268
Echinococcus granulosus	glutamyl tRNA synthetase cytoplasmic	0.0031	0.0564	0.1535
Onchocerca volvulus		0.0029	0.052	0.0861
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Loa Loa (eye worm)	hypothetical protein	0.0023	0.038	0.0461
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0032	0.0588	0.0504
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0104	0.2238	0.6098
Schistosoma mansoni	opsin-like receptor	0.0011	0.0098	0.0268
Trichomonas vaginalis	ABC transporter, putative	0.0132	0.288	0.5493
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Loa Loa (eye worm)	hypothetical protein	0.0082	0.1728	0.2099
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0011	0.0098	0.0268
Leishmania major	myo-inositol/proton symporter (MIT)	0.0015	0.0182	0.0221
Onchocerca volvulus		0.0015	0.0182	0.0201
Echinococcus multilocularis	neuropeptide receptor	0.0011	0.0098	0.0268
Brugia malayi	ABC transporter transmembrane region family protein	0.0041	0.0795	0.0966
Brugia malayi	Sugar transporter family protein	0.0015	0.0182	0.0221
Entamoeba histolytica	ATP-binding cassette protein, putative	0.0041	0.0795	0.1661
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Leishmania major	ATP-binding cassette protein subfamily C, member 1, putative	0.0041	0.0795	0.0966
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.001	0.0079	0.0216
Plasmodium falciparum	ABC transporter B family member 4, putative	0.0041	0.0795	0.0795
Entamoeba histolytica	P-glyco protein 6, putative	0.0132	0.288	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Schistosoma mansoni	smdr2	0.0132	0.288	0.7848
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.0023	0.038	0.0619
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0029	0.052	0.1415
Schistosoma mansoni	hypothetical protein	0.0011	0.0098	0.0268
Trichomonas vaginalis	set domain proteins, putative	0.0232	0.5192	1
Plasmodium falciparum	multidrug resistance-associated protein 1	0.0041	0.0795	0.0795
Echinococcus multilocularis	sodium channel protein	0.0039	0.0735	0.2004
Echinococcus granulosus	neuropeptide receptor A26	0.0011	0.0098	0.0268
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0011	0.0098	0.0268
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0011	0.0098	0.012
Trypanosoma cruzi	lysyl-tRNA synthetase, putative	0.0023	0.038	0.0245
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Brugia malayi	larval opioid receptor	0.0011	0.0098	0.012
Loa Loa (eye worm)	Sodium:neurotransmitter symporter family protein	0.001	0.0079	0.0097
Trichomonas vaginalis	myo-inositol transporter, putative	0.0015	0.0182	0.0233
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Echinococcus multilocularis	solute carrier family 2, facilitated glucose	0.0104	0.2238	0.6098
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Brugia malayi	AKH receptor	0.0011	0.0098	0.012
Echinococcus multilocularis	solute carrier family 22	0.0015	0.0182	0.0496
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Brugia malayi	Calcium/calmodulin-dependent protein kinase type II alpha chain	0.0032	0.0578	0.0703
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0564	0.0685
Echinococcus granulosus	ATP binding cassette sub family B	0.0041	0.0795	0.2167
Onchocerca volvulus		0.0011	0.0098	0.0037
Leishmania major	ATP-binding cassette protein subfamily C, member 8, putative	0.0041	0.0795	0.0966
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0564	0.0685
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Echinococcus multilocularis	multidrug resistance associated protein 1	0.0041	0.0795	0.2167
Trypanosoma brucei	C-8 sterol isomerase, putative	0.0365	0.8232	1
Schistosoma mansoni	voltage-gated potassium channel	0.0013	0.0138	0.0376
Schistosoma mansoni	neuropeptide receptor	0.0011	0.0098	0.0268
Loa Loa (eye worm)	ABC transporter transmembrane region family protein	0.0041	0.0795	0.0966
Trichomonas vaginalis	sugar transporter, putative	0.0032	0.0588	0.1024
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0032	0.0578	0.1576
Onchocerca volvulus		0.0011	0.0098	0.0037
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.001	0.0079	0.0216
Trichomonas vaginalis	taga, putative	0.0132	0.288	0.5493
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Loa Loa (eye worm)	ATP-binding cassette sub-family B member 2	0.0132	0.288	0.3499
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0429	0.0521
Echinococcus multilocularis	ATP binding cassette sub family B	0.0041	0.0795	0.2167
Echinococcus granulosus	multidrug resistance protein 1	0.0132	0.288	0.7848
Schistosoma mansoni	hypothetical protein	0.0011	0.0098	0.0268
Toxoplasma gondii	calcium-dependent protein kinase CDPK2B	0.0032	0.0579	0.0876
Echinococcus granulosus	tm gpcr rhodopsin	0.0011	0.0098	0.0268
Schistosoma mansoni	sodium/chloride dependent transporter	0.0012	0.0125	0.0341
Onchocerca volvulus		0.0011	0.0098	0.0037
Loa Loa (eye worm)	TYRA-2 protein	0.0011	0.0098	0.012
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.0132	0.288	0.7848
Loa Loa (eye worm)	hypothetical protein	0.0132	0.2872	0.3489
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0578	0.0703
Trypanosoma brucei	multidrug resistance-associated protein, putative	0.0041	0.0795	0.0762
Plasmodium falciparum	mitogen-activated protein kinase 2	0.0168	0.3712	0.3712
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0036	0.0682	0.0829
Onchocerca volvulus		0.0011	0.0098	0.0037
Trypanosoma brucei	p-glycoprotein	0.0041	0.0795	0.0762
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0011	0.0098	0.012
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Echinococcus multilocularis	synaptic vesicle 2 protein	0.0015	0.0182	0.0496
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0011	0.0098	0.0268
Brugia malayi	Cam kinase protein 1	0.0032	0.0578	0.0703
Leishmania major	glucose transporter, lmgt3	0.0032	0.0588	0.0714
Schistosoma mansoni	hypothetical protein	0.0011	0.0098	0.0268
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0029	0.052	0.1415
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.001	0.0079	0.0097
Loa Loa (eye worm)	hypothetical protein	0.0082	0.1728	0.2099
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Entamoeba histolytica	protein kinase, putative	0.0032	0.0578	0.0794
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0011	0.0098	0.0268
Loa Loa (eye worm)	hypothetical protein	0.006	0.1222	0.1485
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.0132	0.288	0.5493
Echinococcus granulosus	voltage gated potassium channel	0.0013	0.0138	0.0376
Schistosoma mansoni	sodium/chloride dependent transporter	0.001	0.0079	0.0216
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Plasmodium falciparum	ABC transporter B family member 3, putative	0.0041	0.0795	0.0795
Echinococcus granulosus	sodium and chloride dependent glycine	0.001	0.0079	0.0216
Brugia malayi	putative neuropeptide receptor NPR1	0.0011	0.0098	0.012
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0036	0.0682	0.0622
Mycobacterium tuberculosis	Probable transmembrane multidrug efflux pump	0.0132	0.288	1
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0023	0.038	0.403
Loa Loa (eye worm)	G-protein coupled receptor	0.0011	0.0098	0.012
Echinococcus multilocularis	neuropeptide receptor	0.0011	0.0098	0.0268
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0011	0.0098	0.0268
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Echinococcus multilocularis	g protein coupled receptor	0.0011	0.0098	0.0268
Onchocerca volvulus		0.0015	0.0182	0.0201
Echinococcus granulosus	General substrate transporter	0.0089	0.1902	0.5181
Echinococcus granulosus	cyclic nucleotide gated cation channel alpha 3	0.0009	0.0062	0.017
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.0041	0.0795	0.1429
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0011	0.0098	0.0268
Toxoplasma gondii	lysine-tRNA ligase	0.0023	0.038	0.0575
Loa Loa (eye worm)	Sodium:neurotransmitter symporter family protein	0.001	0.0079	0.0097
Trypanosoma brucei	ABC transporter, mitochondrial, putative	0.0041	0.0795	0.0762
Plasmodium vivax	multidrug resistance protein 2, putative	0.0041	0.0795	0.0721
Echinococcus granulosus	biogenic amine 5HT receptor	0.0011	0.0098	0.0268
Schistosoma mansoni	hypothetical protein	0.0166	0.367	1
Echinococcus granulosus	sodium channel protein	0.0039	0.0735	0.2004
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.0132	0.288	0.5493
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.0132	0.288	0.5493
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0011	0.0098	0.0268
Schistosoma mansoni	amine GPCR	0.0011	0.0098	0.0268
Brugia malayi	hypothetical protein	0.0011	0.0098	0.012
Entamoeba histolytica	ABC transporter, putative	0.0041	0.0795	0.1661
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0011	0.0098	0.0268
Loa Loa (eye worm)	ABC transporter	0.0041	0.0795	0.0966
Leishmania major	glucose transporter/membrane transporter D2, putative	0.0032	0.0588	0.0714
Plasmodium vivax	sugar transporter, putative	0.0015	0.0182	0.0104
Leishmania major	ATP-binding cassette protein subfamily B, member 2, putative	0.0132	0.288	0.3499
Echinococcus granulosus	sodium dependent neurotransmitter transporter	0.001	0.0079	0.0216
Echinococcus multilocularis	fmrfamide receptor	0.0011	0.0098	0.0268
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Brugia malayi	ABC transporter	0.0041	0.0795	0.0966
Loa Loa (eye worm)	melatonin receptor type 1A	0.0011	0.0098	0.012
Trypanosoma cruzi	multidrug resistance-associated protein, putative	0.0041	0.0795	0.0762
Echinococcus granulosus	hypothetical protein	0.0011	0.0098	0.0268
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Brugia malayi	Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog	0.0013	0.0138	0.0167
Trichomonas vaginalis	ABC transporter, putative	0.0132	0.288	0.5493
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.001	0.0079	0.0216
Echinococcus granulosus	g protein coupled receptor	0.0011	0.0098	0.0268
Brugia malayi	ERG2 and Sigma1 receptor like protein	0.0365	0.8232	1
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0011	0.0098	0.012
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0032	0.0588	0.0504
Echinococcus granulosus	sex peptide receptor	0.0011	0.0098	0.0268
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0011	0.0098	0.0268
Loa Loa (eye worm)	CAMK/CAMK2 protein kinase	0.0032	0.0578	0.0703
Echinococcus granulosus	allatostatin A receptor	0.0011	0.0098	0.0268
Onchocerca volvulus		0.0011	0.0098	0.0037
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Schistosoma mansoni	glucose transporter	0.0015	0.0182	0.0496
Echinococcus granulosus	somatostatin receptor	0.0011	0.0098	0.0268
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0011	0.0098	0.0268
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0011	0.0098	0.0037
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0011	0.0098	0.0268
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0009	0.0062	0.017
Toxoplasma gondii	transporter, major facilitator family protein	0.0015	0.0182	0.0276
Echinococcus granulosus	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Echinococcus granulosus	ATP binding cassette sub family B	0.0041	0.0795	0.2167
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0038	0.0721	0.1966
Schistosoma mansoni	glucose transport protein	0.0104	0.2238	0.6098
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Trichomonas vaginalis	glucose transporter, putative	0.0032	0.0588	0.1024
Loa Loa (eye worm)	hypothetical protein	0.001	0.0079	0.0097
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Schistosoma mansoni	voltage-gated potassium channel	0.0041	0.0797	0.2171
Schistosoma mansoni	neuropeptide F-like receptor	0.0011	0.0098	0.0268
Schistosoma mansoni	sugar transporter	0.0015	0.0182	0.0496
Onchocerca volvulus		0.0015	0.0182	0.0201
Loa Loa (eye worm)	hypothetical protein	0.001	0.0079	0.0097
Brugia malayi	Dopamine receptor protein 2	0.0011	0.0098	0.012
Brugia malayi	ABC transporter family protein	0.0041	0.0795	0.0966
Echinococcus granulosus	G protein coupled receptor 139	0.0011	0.0098	0.0268
Trypanosoma brucei	multidrug resistance protein E	0.0041	0.0795	0.0762
Echinococcus granulosus	neuropeptide Y receptor	0.0011	0.0098	0.0268
Echinococcus granulosus	sodium and chloride dependent glycine	0.001	0.0079	0.0216
Leishmania major	protein kinase, putative	0.0032	0.0578	0.0703
Onchocerca volvulus		0.0011	0.0098	0.0037
Brugia malayi	ORL1-like opioid receptor	0.0011	0.0098	0.012
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Trypanosoma brucei	glucose transporter 2A	0.0032	0.0588	0.0504
Echinococcus granulosus	uncharacterized sodium dependent transporter	0.001	0.0079	0.0216
Brugia malayi	Serotonin receptor	0.0011	0.0098	0.012
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0029	0.052	0.1415
Brugia malayi	hypothetical protein	0.0011	0.0098	0.012
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Brugia malayi	Sugar transporter family protein	0.0104	0.2238	0.2719
Giardia lamblia	Multidrug resistance-associated protein 1	0.004	0.0762	0.946
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0138	0.0167
Leishmania major	ATP-binding cassette protein subfamily C, member 6, putative	0.0041	0.0795	0.0966
Onchocerca volvulus		0.0011	0.0098	0.0037
Toxoplasma gondii	sugar transporter ST3	0.0015	0.0182	0.0276
Wolbachia endosymbiont of Brugia malayi	ABC-type protease secretion system, ATPase and permease component, AprD	0.0041	0.0795	1
Loa Loa (eye worm)	hypothetical protein	0.004	0.0762	0.0926
Plasmodium vivax	multidrug resistance-associated protein 2, putative	0.0041	0.0795	0.0721
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.0132	0.288	0.4361
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.004	0.0762	0.1364
Echinococcus granulosus	multidrug resistance associated protein 1	0.0041	0.0795	0.2167
Plasmodium vivax	calcium-dependent protein kinase 3, putative	0.0032	0.0579	0.0503
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 2 LysX	0.002	0.0299	0.0434
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0588	0.0504
Schistosoma mansoni	voltage-gated potassium channel	0.0008	0.0029	0.008
Schistosoma mansoni	smdr1	0.0041	0.0795	0.2167
Schistosoma mansoni	opsin-like receptor	0.0011	0.0098	0.0268
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Mycobacterium ulcerans	integral membrane transport protein	0.0015	0.0182	0.1191
Plasmodium vivax	mitogen-activated protein kinase 2, putative	0.0168	0.3712	0.3661
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.0132	0.288	0.7848
Echinococcus multilocularis	sodium and chloride dependent glycine	0.001	0.0079	0.0216
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.001	0.0079	0.0097
Entamoeba histolytica	P-glycoprotein 6, putative	0.0041	0.0795	0.1661
Echinococcus multilocularis	Sugar transporter ERD6 protein	0.0015	0.0182	0.0496
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0011	0.0098	0.0268
Schistosoma mansoni	sugar transporter	0.0015	0.0182	0.0496
Chlamydia trachomatis	ABC transporter ATP binding protein/permease	0.0132	0.288	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0011	0.0098	0.0268
Plasmodium vivax	hexose transporter	0.0104	0.2238	0.2176
Toxoplasma gondii	ATP-binding cassette sub-family B member 5	0.0041	0.0795	0.1204
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.0041	0.0795	0.1204
Schistosoma mansoni	protein kinase	0.0032	0.0578	0.1576
Leishmania major	ATP-binding cassette protein subfamily C, member 5, putative	0.0041	0.0795	0.0966
Echinococcus multilocularis	multidrug resistance protein 1	0.0132	0.288	0.7848
Brugia malayi	hypothetical protein	0.0011	0.0098	0.012
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.0132	0.288	0.7848
Echinococcus multilocularis	sodium:chloride dependent neurotransmitter	0.001	0.0079	0.0216
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0588	0.0504
Echinococcus multilocularis	General substrate transporter	0.0089	0.1902	0.5181
Echinococcus granulosus	neuropeptide receptor	0.0011	0.0098	0.0268
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0011	0.0098	0.0268
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Plasmodium falciparum	calcium-dependent protein kinase 4	0.0032	0.0579	0.0579
Loa Loa (eye worm)	hypothetical protein	0.0082	0.1728	0.2099
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0011	0.0098	0.0268
Giardia lamblia	Multidrug resistance-associated protein Mrp2	0.004	0.0762	0.946
Onchocerca volvulus		0.0132	0.288	0.5478
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Echinococcus multilocularis	hyperpolarization activated cyclic	0.0009	0.0062	0.017
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Echinococcus multilocularis	g protein coupled receptor	0.0011	0.0098	0.0268
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0011	0.0098	0.0268
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0038	0.0721	0.0876
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0795	0.0966
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0011	0.0098	0.0268
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0038	0.0721	0.1966
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Brugia malayi	Sugar transporter family protein	0.0015	0.0182	0.0221
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Echinococcus granulosus	biogenic amine 5HT receptor	0.0132	0.2872	0.7824
Schistosoma mansoni	multidrug resistance protein	0.0041	0.0795	0.2167
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Echinococcus multilocularis	ATP binding cassette sub family B	0.0041	0.0795	0.2167
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0009	0.0062	0.017
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.0132	0.288	0.5493
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Echinococcus multilocularis	serotonin receptor	0.0132	0.2872	0.7824
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0011	0.0098	0.012
Echinococcus granulosus	calcium dependent protein kinase	0.003	0.0533	0.1452
Entamoeba histolytica	P-glycoprotein 5, putative	0.004	0.0762	0.1529
Schistosoma mansoni	multidrug resistance protein	0.0041	0.0795	0.2167
Schistosoma mansoni	multidrug resistance protein	0.0041	0.0795	0.2167
Plasmodium falciparum	calcium-dependent protein kinase 5	0.0032	0.0579	0.0579
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.0041	0.0795	0.1204
Loa Loa (eye worm)	hypothetical protein	0.0132	0.288	0.3499
Trichomonas vaginalis	glucose transporter, putative	0.0015	0.0182	0.0233
Echinococcus multilocularis	uncharacterized sodium dependent transporter	0.001	0.0079	0.0216
Schistosoma mansoni	amine GPCR	0.0011	0.0098	0.0268
Brugia malayi	multidrug Resistance Protein family member (mrp-5), putative	0.0041	0.0795	0.0966
Echinococcus granulosus	voltage gated sodium channel Nav1 alpha subunit	0.0039	0.0735	0.2004
Entamoeba histolytica	P-glycoprotein 6, putative	0.0041	0.0795	0.1661
Onchocerca volvulus		0.0015	0.0182	0.0201
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Trypanosoma brucei	glucose transporter, putative	0.0032	0.0588	0.0504
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0104	0.2238	0.6098
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0795	0.0966
Entamoeba histolytica	P-glycoprotein-2	0.0132	0.288	1
Toxoplasma gondii	Sodium:neurotransmitter symporter family protein	0.001	0.0079	0.012
Trypanosoma cruzi	hexose transporter, putative	0.0032	0.0588	0.0504
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0011	0.0098	0.0268
Onchocerca volvulus		0.0011	0.0098	0.0037
Trichomonas vaginalis	sugar transporter, putative	0.0032	0.0588	0.1024
Trypanosoma brucei	glucose transporter 1E	0.0032	0.0588	0.0504
Plasmodium falciparum	major facilitator superfamily domain-containing protein, putative	0.0015	0.0182	0.0182
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0011	0.0098	0.0268
Echinococcus granulosus	multidrug resistance protein 1	0.0132	0.288	0.7848
Toxoplasma gondii	protein kinase, putative	0.0294	0.6605	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0011	0.0098	0.0268
Brugia malayi	bifunctional aminoacyl-tRNA synthetase	0.0031	0.0564	0.0685
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0011	0.0098	0.0268
Trichomonas vaginalis	prolyl-tRNA synthetase, putative	0.0031	0.0564	0.0977
Brugia malayi	major facilitator superfamily protein	0.0015	0.0182	0.0221
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0011	0.0098	0.0268
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Onchocerca volvulus		0.0011	0.0098	0.0037
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0011	0.0098	0.0268
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.0041	0.0795	0.1204
Plasmodium vivax	calcium-dependent protein kinase 4, putative	0.0032	0.0579	0.0503
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0015	0.0182	0.0221
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0011	0.0098	0.0268
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0104	0.2238	0.6098
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.0132	0.288	0.5493
Trichomonas vaginalis	ABC transporter, putative	0.0132	0.288	0.5493
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0009	0.0062	0.0076
Brugia malayi	Sodium:neurotransmitter symporter family protein 1, putative	0.001	0.0079	0.0097
Schistosoma mansoni	sodium-dependent amino acid transporter	0.001	0.0079	0.0216
Echinococcus multilocularis	orexin receptor type 2	0.0011	0.0098	0.0268
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Echinococcus granulosus	5'partial\|ATP binding cassette sub family B	0.013	0.2847	0.7758
Echinococcus granulosus	neuropeptide s receptor	0.0011	0.0098	0.0268
Echinococcus multilocularis	G protein coupled receptor 139	0.0011	0.0098	0.0268
Brugia malayi	ABC transporter family protein	0.0132	0.288	0.3499
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0023	0.038	0.403
Echinococcus granulosus	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.0132	0.288	0.7848
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0011	0.0098	0.0268
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0032	0.0578	0.1576
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.0132	0.288	0.5493
Trichomonas vaginalis	ABC transporter, half transporter, putative	0.0132	0.288	0.5493
Leishmania major	glucose transporter, lmgt1	0.0032	0.0588	0.0714
Loa Loa (eye worm)	hypothetical protein	0.006	0.1222	0.1485
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Entamoeba histolytica	prolyl-tRNA synthetase, putative	0.0031	0.0564	0.0735
Mycobacterium leprae	PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER	0.0041	0.0795	1
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.0132	0.288	0.5493
Toxoplasma gondii	hypothetical protein	0.001	0.0079	0.012
Schistosoma mansoni	sodium/chloride dependent transporter	0.006	0.1222	0.3331
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Toxoplasma gondii	sugar transporter ST2	0.0015	0.0182	0.0276
Echinococcus multilocularis	neuropeptide Y receptor	0.0011	0.0098	0.0268
Trypanosoma cruzi	hexose transporter, putative	0.0032	0.0588	0.0504
Echinococcus granulosus	multidrug resistance protein 1	0.0132	0.288	0.7848
Schistosoma mansoni	glucose transport protein	0.0104	0.2238	0.6098
Mycobacterium ulcerans	fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT	0.0015	0.0182	0.1191
Echinococcus granulosus	tm gpcr rhodopsin	0.0011	0.0098	0.0268
Brugia malayi	RE15519p	0.0011	0.0098	0.012
Echinococcus granulosus	7tm_1 domain containing protein	0.0011	0.0098	0.0268
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0011	0.0098	0.0268
Entamoeba histolytica	P-glycoprotein-2, putative	0.0132	0.288	1
Plasmodium falciparum	protein kinase 7	0.0294	0.6605	0.6605
Echinococcus granulosus	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Leishmania major	C-8 sterol isomerase-like protein	0.0365	0.8232	1
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.0132	0.288	0.5493
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Entamoeba histolytica	P-glycoprotein-5	0.0132	0.288	1
Plasmodium falciparum	amino acid transporter, putative	0.001	0.0079	0.0079
Mycobacterium tuberculosis	Probable drugs-transport transmembrane ATP-binding protein ABC transporter	0.0041	0.0795	0.2272
Echinococcus granulosus	hyperpolarization activated cyclic	0.0009	0.0062	0.017
Plasmodium falciparum	calcium-dependent protein kinase 1	0.0032	0.0579	0.0579
Trichomonas vaginalis	conserved hypothetical protein	0.004	0.0762	0.1364
Schistosoma mansoni	hypothetical protein	0.0011	0.0098	0.0268
Schistosoma mansoni	multidrug resistance protein	0.0132	0.288	0.7848
Entamoeba histolytica	ATP-binding cassette protein, putative	0.0041	0.0795	0.1661
Brugia malayi	Bifunctional aminoacyl-tRNA synthetase	0.0031	0.0564	0.0685
Giardia lamblia	Hypothetical protein	0.004	0.0762	0.946
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0011	0.0098	0.0268
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0009	0.0062	0.0076
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.0041	0.0795	0.1204
Schistosoma mansoni	ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7)	0.0041	0.0795	0.2167
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0011	0.0098	0.012
Echinococcus granulosus	solute carrier family 22	0.0015	0.0182	0.0496
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.0132	0.288	0.5493
Echinococcus granulosus	solute carrier family 22	0.0015	0.0182	0.0496
Trypanosoma brucei	multidrug resistance-associated protein, putative	0.0041	0.0795	0.0762
Trichomonas vaginalis	sugar transporter, putative	0.0015	0.0182	0.0233
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0011	0.0098	0.0268
Onchocerca volvulus		0.0015	0.0182	0.0201
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.0132	0.288	0.5493
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0098	0.012
Loa Loa (eye worm)	ABC transporter	0.0041	0.0795	0.0966
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0182	0.0221
Loa Loa (eye worm)	hypothetical protein	0.001	0.0079	0.0097
Trichomonas vaginalis	abcb9, putative	0.0132	0.288	0.5493
Trypanosoma cruzi	multidrug resistance-associated protein, putative	0.0041	0.0795	0.0762
Brugia malayi	ABC transporter family protein	0.0041	0.0795	0.0966
Loa Loa (eye worm)	hypothetical protein	0.006	0.1222	0.1485
Brugia malayi	hypothetical protein	0.0015	0.0182	0.0221
Brugia malayi	Melatonin receptor type 1A	0.0011	0.0098	0.012
Echinococcus granulosus	rhodopsin orphan GPCR	0.0011	0.0098	0.0268
Loa Loa (eye worm)	sugar transporter	0.0015	0.0182	0.0221
Brugia malayi	major facilitator superfamily protein	0.0015	0.0182	0.0221
Echinococcus multilocularis	solute carrier family 22	0.0015	0.0182	0.0496

Activities

Activity type	Activity value	Assay description	Source	Reference
Activity (functional)	= 0	Value is expressed as the ratio of (T. foetus) animals cured / total number(5) infected at day 4 post treatment after 4 days of treatment	ChEMBL.	4067993
Activity (functional)	= 4	Value is expressed as the ratio of (T. foetus) animals cured / total number(5) infected at day 1 post treatment after 4 days of treatment	ChEMBL.	4067993
MLC (functional)	= 50 ug ml-1	The minimum lethal concentration (MLC) against Trichomonas foetus	ChEMBL.	4067993

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL442160

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 65681