Detailed information for compound 674620

Basic information

Technical information
  • TDR Targets ID: 674620
  • Name: 5-bromo-N-[4-(4-butanoylpiperazin-1-yl)-3-chl orophenyl]-2-chlorobenzamide
  • MW: 499.228 | Formula: C21H22BrCl2N3O2
  • H donors: 1 H acceptors: 2 LogP: 4.93 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC(=O)N1CCN(CC1)c1ccc(cc1Cl)NC(=O)c1cc(Br)ccc1Cl
  • InChi: 1S/C21H22BrCl2N3O2/c1-2-3-20(28)27-10-8-26(9-11-27)19-7-5-15(13-18(19)24)25-21(29)16-12-14(22)4-6-17(16)23/h4-7,12-13H,2-3,8-11H2,1H3,(H,25,29)
  • InChiKey: ROUSTZVHHZSQTH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 5-bromo-N-[4-(4-butanoylpiperazin-1-yl)-3-chloro-phenyl]-2-chloro-benzamide
  • 5-bromo-2-chloro-N-[3-chloro-4-[4-(1-oxobutyl)-1-piperazinyl]phenyl]benzamide
  • 5-bromo-N-[4-(4-butyrylpiperazin-1-yl)-3-chloro-phenyl]-2-chloro-benzamide
  • STK255165

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis ewsr:fli fusion protein type 0.001 0.007 0.0072
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0442 0.0642
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0228 0.0317
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.017 0.0244
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0315 0.046
Leishmania major GTP-binding protein, putative 0.0021 0.0196 0.027
Entamoeba histolytica serine/threonine protein kinase, putative 0.0585 0.6858 1
Schistosoma mansoni coup transcription factor 0.001 0.0065 0.0062
Schistosoma mansoni hypothetical protein 0.0036 0.0369 0.0366
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.017 0.0177
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0065 0.009
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0228 0.0239
Brugia malayi hypothetical protein 0.0019 0.017 0.0248
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0196 0.0276
Brugia malayi kap beta 3 protein 0.0005 0.0011 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.017 0.0248
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Brugia malayi hypothetical protein 0.0005 0.0003 0.0004
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0063 0.0092
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0442 0.0641
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0063 0.0088
Schistosoma mansoni importin beta-1 0.0029 0.0285 0.0282
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.017 0.0177
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0742 0.1082
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) RNA binding protein 0.0062 0.0683 0.0996
Brugia malayi Patched protein homolog 1 0.0006 0.0017 0.0025
Schistosoma mansoni thyroid hormone receptor 0.001 0.0065 0.0062
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0142 0.1631 0.1629
Loa Loa (eye worm) patched family protein 0.0006 0.0017 0.0025
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0063 0.0064
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0459 0.5374 0.5689
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Brugia malayi hypothetical protein 0.0006 0.0017 0.0025
Echinococcus multilocularis ets variant gene 4 0.001 0.007 0.0072
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Brugia malayi Patched related family protein 10 0.0006 0.0017 0.0025
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0067 0.0742 0.1082
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0315 0.0331
Schistosoma mansoni hypothetical protein 0.004 0.0424 0.0422
Schistosoma mansoni hypothetical protein 0.0031 0.0315 0.0313
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0401 1
Schistosoma mansoni axis inhibition protein axin 0.0019 0.017 0.0167
Loa Loa (eye worm) hypothetical protein 0.0098 0.111 0.1619
Loa Loa (eye worm) hypothetical protein 0.012 0.1361 0.1984
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0065 0.0062
Plasmodium vivax transportin, putative 0.0005 0.0011 0.016
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Entamoeba histolytica hypothetical protein 0.0019 0.017 0.0242
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.11 0.1599
Echinococcus granulosus axis inhibition protein axin 0.0019 0.017 0.0244
Loa Loa (eye worm) D-ets-2 protein 0.001 0.007 0.0103
Onchocerca volvulus Protein patched homolog 0.0006 0.0017 0.0021
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0585 0.6858 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0285 0.04
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0196 0.4734
Brugia malayi steroid hormone receptor 0.001 0.0065 0.0094
Schistosoma mansoni hypothetical protein 0.0067 0.0742 0.074
Echinococcus granulosus Smad4 0.0008 0.0043 0.0058
Loa Loa (eye worm) DR-78 0.0005 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Brugia malayi hypothetical protein 0.0006 0.0017 0.0025
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.017 0.0167
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0442 1
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.017 0.0248
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0795 0.084
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0063 0.0092
Loa Loa (eye worm) hypothetical protein 0.0029 0.0285 0.0416
Loa Loa (eye worm) nuclear hormone receptor 0.0005 0.0003 0.0004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0483 0.0509
Echinococcus multilocularis ETS transcription factor Elf 1 0.001 0.007 0.0072
Onchocerca volvulus 0.0006 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Echinococcus granulosus ETS transcription factor Elf 5 0.001 0.007 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0202 0.0199
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0683 0.0681
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0065 0.009
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0005 0.0009 0.0014
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0005 0.0003 0.0004
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.1584 0.2307
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.017 0.0248
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.001 0.0063 0.1335
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.111 0.1619
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Echinococcus granulosus importin 5 0.0005 0.0011 0.0012
Echinococcus granulosus axis inhibition protein axin 0.0019 0.017 0.0244
Toxoplasma gondii patched family protein 0.0006 0.0017 0.0248
Loa Loa (eye worm) hypothetical protein 0.0005 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0031 0.0315 0.046
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0221 0.0307
Echinococcus granulosus ewsr:fli fusion protein type 0.001 0.007 0.0099
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0202 0.0211
Schistosoma mansoni DNA helicase recq5 0.001 0.0063 0.0061
Schistosoma mansoni blooms syndrome DNA helicase 0.0005 0.0006 0.0004
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0065 0.0094
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.007 0.0103
Schistosoma mansoni hypothetical protein 0.0031 0.0315 0.0313
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.007 0.0103
Onchocerca volvulus 0.0006 0.0017 0.0021
Leishmania major importin beta-1 subunit, putative 0.0023 0.0221 0.0307
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.017 0.0248
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0065 0.0094
Brugia malayi Ets-domain containing protein 0.0072 0.0795 0.116
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0065 0.0062
Onchocerca volvulus 0.001 0.0065 0.009
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0065 0.0066
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.017 0.0248
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0065 0.009
Echinococcus multilocularis snurportin 1 0.0305 0.3552 0.376
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0005 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Schistosoma mansoni regulator of G protein signaling 0.0019 0.017 0.0167
Brugia malayi hypothetical protein 0.0036 0.0369 0.0538
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0483 0.0704
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0065 0.009
Toxoplasma gondii hypothetical protein 0.0006 0.0017 0.0248
Echinococcus multilocularis protein C ets 2 0.001 0.007 0.0072
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0169 0.0166
Echinococcus granulosus smad 0.0008 0.0043 0.0058
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0065 0.0066
Brugia malayi nuclear hormone receptor family member odr-7 0.0005 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0061 0.0667 0.0973
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.001 0.007 0.0103
Brugia malayi MH2 domain containing protein 0.0008 0.0043 0.0062
Brugia malayi DNA-binding protein D-ETS-3 0.001 0.007 0.0103
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0065 0.0062
Trypanosoma cruzi polo-like protein kinase, putative 0.0585 0.6858 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0065 0.0094
Brugia malayi Importin beta-1 subunit 0.0029 0.0285 0.0416
Brugia malayi Patched related family protein 12 0.0006 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0043 0.0058
Brugia malayi MH2 domain containing protein 0.0118 0.1345 0.1962
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0065 0.0094
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Schistosoma mansoni hypothetical protein 0.0031 0.0315 0.0313
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0005 0.0003 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.017 0.0232
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0202 0.0199
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0483 0.0509
Brugia malayi nuclear hormone receptor 0.0005 0.0003 0.0004
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.017 0.0177
Trichomonas vaginalis ran, putative 0.0021 0.0196 0.027
Onchocerca volvulus 0.0006 0.0017 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.017 0.0232
Schistosoma mansoni thyroid hormone receptor 0.001 0.0065 0.0062
Loa Loa (eye worm) importin-beta domain-containing protein 0.0005 0.0011 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0065 0.0094
Echinococcus granulosus snurportin 1 0.0305 0.3552 0.5178
Loa Loa (eye worm) hypothetical protein 0.0019 0.017 0.0248
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0043 0.004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0065 0.0094
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0061 0.0672 0.0977
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0065 0.0094
Echinococcus granulosus ETS domain containing protein Elk 1 0.001 0.007 0.0099
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0097 0.0126
Brugia malayi RNA, U transporter 1 0.0081 0.0908 0.1323
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.001 0.0063 0.0092
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0065 0.0094
Schistosoma mansoni regulator of G protein signaling 0.0019 0.017 0.0167
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0065 0.009
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0683 0.0681
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.2232 0.3243
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0369 0.0388
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.007 0.0072
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.017 0.0244
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0196 0.0282
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0142 0.1631 0.1725
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.017 0.0232
Schistosoma mansoni ets-related 0.001 0.007 0.0068
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Brugia malayi protein C24B5.3 0.0006 0.0017 0.0025
Echinococcus granulosus transportin 1 0.0005 0.0011 0.0012
Schistosoma mansoni regulator of G protein signaling 0.0019 0.017 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0442 0.0629
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0065 0.009
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0043 0.0062
Brugia malayi protein C24B5.3 0.0006 0.0017 0.0025
Toxoplasma gondii HEAT repeat-containing protein 0.0005 0.0011 0.011
Schistosoma mansoni hypothetical protein 0.004 0.0424 0.0422
Brugia malayi orphan nuclear receptor NR2E1 0.0005 0.0003 0.0004
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.111 0.1619
Loa Loa (eye worm) hypothetical protein 0.0019 0.017 0.0248
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0065 0.0062
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.017 0.0244
Brugia malayi TAR-binding protein 0.0062 0.0683 0.0996
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0065 0.009
Entamoeba histolytica recQ family DNA helicase 0.0005 0.0006 0.0003
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0065 0.0094
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.017 0.0177
Entamoeba histolytica Ran family GTPase 0.0021 0.0196 0.028
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Brugia malayi serine/threonine-protein kinase plk-2 0.0585 0.6858 1
Brugia malayi hypothetical protein 0.0005 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0005 0.0009 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0065 0.0094
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0483 0.0701
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.017 0.0167
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0065 0.0094
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0065 0.0062
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0442 0.0465
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0065 0.0094
Onchocerca volvulus Protein patched homolog 0.0006 0.0017 0.0021
Schistosoma mansoni smad1 5 8 and 0.0008 0.0043 0.004
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0043 0.0062
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0683 0.0721
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0202 0.0294
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0315 0.0456
Loa Loa (eye worm) hypothetical protein 0.0005 0.0009 0.0014
Brugia malayi PXA domain containing protein 0.0019 0.017 0.0248
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0065 0.0094
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0315 0.0331
Brugia malayi PXA domain containing protein 0.0019 0.017 0.0248
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0005 0.0009 0.0007
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0442 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0065 0.0094
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0065 0.0062
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.017 0.0177
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.017 0.0177
Schistosoma mansoni hypothetical protein 0.001 0.007 0.0068
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0683 0.0681
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0483 0.0701
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Loa Loa (eye worm) patched family protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) Smad1 0.0008 0.0043 0.0062
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0683 0.0996
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0315 0.0456
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0065 0.0066
Schistosoma mansoni hypothetical protein 0.0305 0.3552 0.355
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0065 0.0066
Entamoeba histolytica hypothetical protein 0.0036 0.0369 0.0532
Echinococcus multilocularis ETS domain containing protein Elk 1 0.001 0.007 0.0072
Brugia malayi hypothetical protein 0.0005 0.0009 0.0014
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0315 0.046
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0483 0.048
Loa Loa (eye worm) hypothetical protein 0.0019 0.017 0.0248
Trichomonas vaginalis CAMK family protein kinase 0.0585 0.6858 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.017 0.0248
Echinococcus granulosus protein C ets 2 0.001 0.007 0.0099
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0065 0.0066
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0194 0.4688
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0065 0.0094
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0094
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0196 0.0286
Schistosoma mansoni serine/threonine protein kinase 0.0585 0.6858 0.6857
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0401 0.0497
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0585 0.6858 0.7261
Plasmodium vivax importin-beta 2, putative 0.0029 0.0285 0.6407
Loa Loa (eye worm) hypothetical protein 0.0061 0.0672 0.098
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0043 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.017 0.0232
Echinococcus multilocularis smad 0.0008 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0094
Loa Loa (eye worm) fli-1 protein 0.0218 0.2522 0.3678
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.007 0.0103
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0094
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0683 0.0996
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0202 0.0294
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.11 0.1163
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0315 0.046
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.0009 0.0007
Brugia malayi MH1 domain containing protein 0.0008 0.0043 0.0062
Schistosoma mansoni Smad4 0.0008 0.0043 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0585 0.6858 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0442 1
Trypanosoma brucei polo-like protein kinase 0.0585 0.6858 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0065 0.0066
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0202 0.029
Loa Loa (eye worm) patched family protein 0.0006 0.0017 0.0025
Schistosoma mansoni hypothetical protein 0.004 0.0424 0.0422
Schistosoma mansoni smad1 5 8 and 0.0008 0.0043 0.004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0483 0.048
Schistosoma mansoni hypothetical protein 0.004 0.0424 0.0422
Echinococcus granulosus tar DNA binding protein 0.0062 0.0683 0.0993
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Brugia malayi Smad1 0.0008 0.0043 0.0062
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0221 0.0307
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0228 0.0317
Brugia malayi tailless protein 0.0005 0.0003 0.0004
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0459 0.5374 0.7835
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0009 0.0014
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0795 0.1156
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0065 0.009
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0483 0.0704
Brugia malayi Protein kinase domain containing protein 0.0061 0.0667 0.0973
Plasmodium vivax patched family protein, putative 0.0006 0.0017 0.0298
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.017 0.0167
Echinococcus multilocularis GPCR, family 2 0.0031 0.0315 0.0331
Schistosoma mansoni nuclear hormone receptor 0.001 0.0065 0.0062
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0305 0.3552 0.518
Echinococcus granulosus FTZ F1 alpha 0.001 0.0065 0.009
Schistosoma mansoni hypothetical protein 0.001 0.007 0.0068
Schistosoma mansoni DNA helicase recq1 0.001 0.0063 0.0061
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0063 0.1303
Echinococcus granulosus ETS transcription factor Elf 1 0.001 0.007 0.0099
Loa Loa (eye worm) hypothetical protein 0.001 0.007 0.0103
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0285 0.0299
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0221 0.0307
Brugia malayi Myosin head containing protein 0.0006 0.0017 0.0025
Brugia malayi hypothetical protein 0.0005 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.017 0.0248
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.2232 0.3243
Brugia malayi hypothetical protein 0.0006 0.0017 0.0025
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0137 0.3035
Schistosoma mansoni smad1 5 8 and 0.0008 0.0043 0.004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0065 0.0066
Echinococcus multilocularis ETS transcription factor Elf 5 0.001 0.007 0.0072
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Brugia malayi nuclear receptor NHR-88 0.001 0.0065 0.0094
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0009
Echinococcus granulosus translational activator gcn1 0.0005 0.0011 0.0012
Echinococcus granulosus bloom syndrome protein 0.0024 0.0228 0.0329
Entamoeba histolytica hypothetical protein 0.0019 0.017 0.0242
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0228 0.0333
Entamoeba histolytica hypothetical protein 0.0036 0.0369 0.0532
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0094
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0401 0.0579
Loa Loa (eye worm) hypothetical protein 0.0005 0.0009 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0683 0.0681
Loa Loa (eye worm) nuclear receptor NHR-67 0.0005 0.0003 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0585 0.6858 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0065 0.0094
Loa Loa (eye worm) RGS-3 protein 0.0019 0.017 0.0248
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.017 0.0232
Schistosoma mansoni ran 0.0021 0.0196 0.0193
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.017 0.0177
Schistosoma mansoni patched 1 0.0042 0.0442 0.0439
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0063 0.1303
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0683 0.0681
Schistosoma mansoni hypothetical protein 0.0031 0.0315 0.0313
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0065 0.0066
Trichomonas vaginalis CAMK family protein kinase 0.0585 0.6858 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.1345 0.1962
Onchocerca volvulus 0.0006 0.0017 0.0021
Brugia malayi Ets-domain containing protein 0.001 0.007 0.0103
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0063 0.0064
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0063 0.0092
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0097 0.0126
Entamoeba histolytica hypothetical protein 0.0019 0.017 0.0242
Brugia malayi ecdysteroid receptor 0.001 0.0065 0.0094
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0135 0.2948
Plasmodium falciparum lipid/sterol:H+ symporter 0.0006 0.0017 0.0155
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0065 0.0062
Schistosoma mansoni ets 0.001 0.007 0.0068
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0803 0.9443 1
Echinococcus multilocularis Smad4 0.0008 0.0043 0.0042
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0065 0.009
Brugia malayi nuclear receptor RXR 0.0005 0.0003 0.0004
Echinococcus multilocularis importin 5 0.0005 0.0011 0.0009
Loa Loa (eye worm) RecQ helicase 0.0024 0.0228 0.0333
Onchocerca volvulus Serine\/threonine kinase homolog 0.0585 0.6858 1
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.017 0.0248
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0196 0.0286
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0442 0.063
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.017 0.0177
Schistosoma mansoni axis inhibition protein axin 0.0019 0.017 0.0167
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0585 0.6858 1
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Toxoplasma gondii patched family protein 0.0006 0.0017 0.0248
Brugia malayi nuclear receptor NHR-67 0.0005 0.0003 0.0004
Brugia malayi acetyltransferase, GNAT family protein 0.0142 0.1631 0.2379
Echinococcus granulosus importin subunit beta 1 0.0029 0.0285 0.0412
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.1595 0.2323
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0065 0.0062
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0585 0.6858 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.007 0.0099
Trichomonas vaginalis CAMK family protein kinase 0.0585 0.6858 1
Trichomonas vaginalis CAMK family protein kinase 0.0585 0.6858 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0094
Schistosoma mansoni smad 0.0008 0.0043 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0585 0.6858 1
Echinococcus granulosus expressed protein 0.0367 0.4284 0.6245
Brugia malayi MH1 domain containing protein 0.0008 0.0043 0.0062
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.1345 0.1962
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0043 0.0042
Schistosoma mansoni regulator of G protein signaling 0.0019 0.017 0.0167
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0097 0.0133
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0094
Onchocerca volvulus 0.0006 0.0017 0.0021
Onchocerca volvulus 0.0006 0.0017 0.0021
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0196 0.027
Brugia malayi ecdysone receptor 0.0005 0.0003 0.0004
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.007 0.0068
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0065 0.0062
Toxoplasma gondii patched family protein 0.0006 0.0017 0.0248
Loa Loa (eye worm) patched family protein 0.0006 0.0017 0.0025
Echinococcus multilocularis protein dispatched 1 0.0048 0.0512 0.0539
Echinococcus multilocularis expressed conserved protein 0.0092 0.103 0.1089
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0795 0.116
Entamoeba histolytica hypothetical protein 0.0036 0.0369 0.0532
Brugia malayi nuclear hormone receptor family member nhr-6 0.0005 0.0003 0.0004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0065 0.009
Brugia malayi transcription factor E74 isoform 0.001 0.007 0.0103
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0003 0.0004
Onchocerca volvulus 0.0006 0.0017 0.0021
Schistosoma mansoni ets-related 0.0218 0.2522 0.252
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.017 0.0248
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0196 0.4373
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.017 0.0248
Entamoeba histolytica hypothetical protein 0.0023 0.0221 0.0317
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0009 0.0014
Brugia malayi Fli-1 protein 0.0218 0.2522 0.3678
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0003 0.0004
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0097 0.0126
Brugia malayi MH2 domain containing protein 0.0008 0.0043 0.0062
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.1118 0.1116
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.017 0.0232
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0065 0.0094
Brugia malayi nuclear receptor RXR 0.0005 0.0009 0.0014
Loa Loa (eye worm) acetyltransferase 0.0142 0.1631 0.2379
Loa Loa (eye worm) hypothetical protein 0.0005 0.0003 0.0004
Echinococcus multilocularis translational activator gcn1 0.0005 0.0011 0.0009
Brugia malayi hypothetical protein 0.0019 0.017 0.0248
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.11 0.1604
Echinococcus granulosus GPCR family 2 0.0031 0.0315 0.0456
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.017 0.0244
Loa Loa (eye worm) patched family protein 0.0006 0.0017 0.0025
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0442 0.063
Loa Loa (eye worm) hypothetical protein 0.001 0.0065 0.0094
Trypanosoma cruzi polo-like protein kinase, putative 0.0585 0.6858 1
Schistosoma mansoni ran 0.0021 0.0196 0.0193
Brugia malayi nuclear hormone receptor 0.001 0.0065 0.0094
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0065 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0065 0.0094
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Toxoplasma gondii HEAT repeat-containing protein 0.0005 0.0011 0.011
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0196 0.0195
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0285 0.6388
Echinococcus granulosus expressed conserved protein 0.0092 0.103 0.1499
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0202 0.0294
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.017 0.0167
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0683 0.0996
Schistosoma mansoni gabp alpha 0.0072 0.0795 0.0793
Brugia malayi RNA binding protein 0.0062 0.0683 0.0996
Brugia malayi conserved hypotetical protein 0.0005 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Schistosoma mansoni elf1 0.001 0.007 0.0068
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0005 0.0009 0.0007
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0097 0.0136
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0061 0.0667 0.0704
Entamoeba histolytica hypothetical protein 0.0036 0.0369 0.0532
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.007 0.0099
Loa Loa (eye worm) hypothetical protein 0.0051 0.0553 0.0807
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Brugia malayi Patched related family protein 4 0.0006 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0098 0.11 0.1604
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0065 0.0094
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0063 0.0088
Entamoeba histolytica HEAT repeat domain containing protein 0.0005 0.0011 0.001
Echinococcus multilocularis transportin 1 0.0005 0.0011 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0065 0.0094
Toxoplasma gondii patched family protein 0.0006 0.0017 0.0248
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0065 0.0094
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0196 0.4344
Brugia malayi hypothetical protein 0.0006 0.0017 0.0025
Brugia malayi nuclear receptor NHR-88 0.0005 0.0003 0.0004
Brugia malayi CHE-14 protein 0.0042 0.0442 0.0645
Schistosoma mansoni regulator of G protein signaling 0.0019 0.017 0.0167
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.007 0.0072
Brugia malayi Patched family protein 0.0006 0.0017 0.0025
Plasmodium falciparum importin beta, putative 0.0029 0.0285 0.702
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0065 0.0094
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0442 0.0645
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.017 0.0244
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0483 0.048
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0065 0.009
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0025
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0196 0.0205
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0442 0.0641
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0285 0.04
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0369 0.0534
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.017 0.0177
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0065 0.0094
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0369 0.0366
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0008 0.0043 0.0046
Echinococcus multilocularis expressed protein 0.0367 0.4284 0.4535
Giardia lamblia Kinase, PLK 0.0585 0.6858 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.1595 0.1687
Brugia malayi Ets-domain containing protein 0.0072 0.0795 0.116
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0065 0.0094
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.017 0.0244
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.11 0.1601
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.111 0.1619
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.017 0.0232
Echinococcus multilocularis protein patched 0.0042 0.0442 0.0465
Treponema pallidum ATP-dependent DNA helicase 0.0005 0.0006 0.5
Loa Loa (eye worm) kap beta 3 protein 0.0005 0.0011 0.0016
Loa Loa (eye worm) hypothetical protein 0.0042 0.0442 0.0645
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0043 0.0058
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0221 0.0313
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0196 0.0276
Schistosoma mansoni importin-beta 2 0.0005 0.0011 0.0008
Loa Loa (eye worm) hypothetical protein 0.0005 0.0009 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0202 0.0199

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.