Detailed information for compound 779110

Basic information

Technical information
  • TDR Targets ID: 779110
  • Name: 5-(4-propan-2-yloxyphenyl)-2-thiophen-2-yl-5, 10b-dihydro-1H-pyrazolo[1,5-c][1,3]benzoxazin e
  • MW: 390.498 | Formula: C23H22N2O2S
  • H donors: 0 H acceptors: 0 LogP: 5.62 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(Oc1ccc(cc1)C1Oc2ccccc2C2N1N=C(C2)c1cccs1)C
  • InChi: 1S/C23H22N2O2S/c1-15(2)26-17-11-9-16(10-12-17)23-25-20(18-6-3-4-7-21(18)27-23)14-19(24-25)22-8-5-13-28-22/h3-13,15,20,23H,14H2,1-2H3
  • InChiKey: WSIWAJCXUOXHOJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-(4-isopropoxyphenyl)-2-(2-thienyl)-5,10b-dihydro-1H-pyrazolo[1,5-c][1,3]benzoxazine
  • EU-0079972

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.1427 0.1896
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0512 0.226
Schistosoma mansoni opsin-like receptor 0.0056 0.0514 0.067
Echinococcus granulosus tm gpcr rhodopsin 0.0056 0.0514 0.067
Trypanosoma brucei glucose transporter, putative 0.0065 0.0621 0.1939
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0889 0.0996
Giardia lamblia Lysyl-tRNA synthetase 0.0047 0.0413 0.5444
Onchocerca volvulus 0.0031 0.0229 0.1215
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0077 0.0757 0.3298
Brugia malayi RE15519p 0.0056 0.0514 0.2218
Brugia malayi G protein-coupled receptor F59B2.13 0.0056 0.0514 0.2218
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0077 0.0757 0.0845
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Echinococcus multilocularis neuropeptide receptor A26 0.0056 0.0514 0.0568
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0338 0.0368
Brugia malayi Dopamine receptor 0.0056 0.0514 0.2218
Schistosoma mansoni rotamase 0.0066 0.0628 0.0822
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0038 0.0233
Loa Loa (eye worm) hypothetical protein 0.0047 0.0414 0.1772
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0056 0.0514 0.067
Schistosoma mansoni biogenic amine (5HT) receptor 0.0056 0.0514 0.067
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.0038 0.0022
Trichomonas vaginalis myo-inositol transporter, putative 0.0029 0.0217 0.0956
Echinococcus granulosus peptide allatostatin:somatostatin 0.0056 0.0514 0.067
Loa Loa (eye worm) sugar transporter 0.0029 0.0217 0.0894
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0014 0.0038 0.0233
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0031 0.0229 0.095
Plasmodium falciparum protein kinase 7 0.0592 0.6619 0.6614
Brugia malayi Cam kinase protein 1 0.0065 0.0616 0.2672
Loa Loa (eye worm) hypothetical protein 0.004 0.0338 0.1434
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0514 0.0568
Onchocerca volvulus 0.0029 0.0217 0.1134
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) G-protein coupled receptor 0.0056 0.0514 0.2218
Plasmodium falciparum calcium-dependent protein kinase 5 0.0065 0.0617 0.0602
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0616 0.0685
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0338 0.1208
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0338 0.1208
Echinococcus multilocularis geminin 0.0529 0.5895 0.67
Schistosoma mansoni biogenic amine (5HT) receptor 0.0056 0.0514 0.067
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0338 0.1057
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0038 0.0099
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0038 0.0233
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.0512 0.1599
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Schistosoma mansoni sugar transporter 0.0029 0.0217 0.027
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0077 0.0757 0.3298
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0247 0.0232
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0258 0.0921
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0179
Loa Loa (eye worm) hypothetical protein 0.0046 0.0409 0.1752
Echinococcus granulosus g protein coupled receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) TYRA-2 protein 0.0056 0.0514 0.2218
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Onchocerca volvulus 0.0029 0.0217 0.1134
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.0512 0.0565
Leishmania major glucose transporter, lmgt3 0.0065 0.0621 0.1939
Brugia malayi hypothetical protein 0.0029 0.0217 0.0894
Plasmodium falciparum calcium-dependent protein kinase 4 0.0065 0.0617 0.0602
Schistosoma mansoni glucose transport protein 0.021 0.2264 0.3019
Loa Loa (eye worm) hypothetical protein 0.0041 0.0346 0.1468
Trypanosoma brucei glucose transporter, putative 0.0065 0.0621 0.1939
Echinococcus multilocularis solute carrier family 22 0.0029 0.0217 0.0229
Echinococcus multilocularis serotonin receptor 0.0056 0.0514 0.0568
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.1452 0.4538
Echinococcus granulosus 7TM GPCR rhodopsin 0.0056 0.0514 0.067
Trichomonas vaginalis esterase, putative 0.004 0.0338 0.1493
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0038 0.003
Onchocerca volvulus 0.0029 0.0217 0.1134
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Loa Loa (eye worm) hypothetical protein 0.0046 0.0409 0.1752
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0014 0.0038 0.0233
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0038 0.0099
Echinococcus multilocularis solute carrier family 22 0.0029 0.0217 0.0229
Schistosoma mansoni nAChR subunit 0.0077 0.0757 0.0996
Mycobacterium tuberculosis Conserved protein 0.004 0.0338 0.1208
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0077 0.0757 0.3298
Brugia malayi G-protein coupled receptor 0.0056 0.0514 0.2218
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0514 0.067
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0016 0.0069
Onchocerca volvulus 0.0056 0.0514 0.3025
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0715 0.2234
Echinococcus granulosus neuropeptide receptor 0.0056 0.0514 0.067
Brugia malayi hypothetical protein 0.0031 0.0229 0.095
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0016 0.0024
Echinococcus multilocularis g-protein coupled receptor 0.0056 0.0514 0.0568
Echinococcus granulosus nAChR subunit 0.0077 0.0757 0.0996
Echinococcus granulosus alpha 1A adrenergic receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0056 0.0514 0.2218
Plasmodium vivax acetyl-CoA synthetase, putative 0.0014 0.0038 0.0022
Onchocerca volvulus 0.0056 0.0514 0.3025
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0063 0.0596 0.0662
Schistosoma mansoni hypothetical protein 0.0039 0.0329 0.0421
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0109 0.0339
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.1427 0.1609
Loa Loa (eye worm) hypothetical protein 0.0152 0.1613 0.7104
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0029 0.0217 0.0774
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0381 0.1683
Brugia malayi ORL1-like opioid receptor 0.0056 0.0514 0.2218
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0031 0.0229 0.095
Schistosoma mansoni neuropeptide F-like receptor 0.0056 0.0514 0.067
Schistosoma mansoni neuropeptide receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0038 0.0135
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.002 0.0109 0.0164
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0046 0.0409 0.1752
Schistosoma mansoni amine GPCR 0.0056 0.0514 0.067
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0077 0.0757 0.0996
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0715 0.2234
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0346 0.0443
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0715 0.2234
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0077 0.0757 0.3298
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0229 0.095
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0029 0.0217 0.1329
Giardia lamblia Prolyl-tRNA synthetase 0.0063 0.0596 0.7949
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Toxoplasma gondii facilitative glucose transporter GT1 0.021 0.2264 0.3421
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0414 0.1479
Trypanosoma brucei glucose transporter, putative 0.0065 0.0621 0.1939
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus multilocularis expressed conserved protein 0.0089 0.0898 0.1005
Plasmodium falciparum pantothenate kinase 2, putative 0.0032 0.0247 0.0232
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0077 0.0757 0.3298
Echinococcus multilocularis GPCR, family 2 0.0015 0.0056 0.0046
Plasmodium vivax hexose transporter 0.021 0.2264 0.2252
Schistosoma mansoni sugar transporter 0.0029 0.0217 0.027
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0414 0.1772
Brugia malayi CHE-14 protein 0.0041 0.0346 0.1468
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0014 0.0038 0.0233
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0414 0.2541
Echinococcus multilocularis somatostatin receptor 0.0056 0.0514 0.0568
Echinococcus granulosus biogenic amine 5HT receptor 0.0056 0.0514 0.067
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0338 0.1208
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0425 0.055
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0078 0.0768 0.24
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0077 0.0757 0.0996
Mycobacterium ulcerans hypothetical protein 0.0047 0.0414 0.2541
Loa Loa (eye worm) hypothetical protein 0.0046 0.0409 0.1752
Mycobacterium ulcerans lipase LipD 0.004 0.0338 0.2075
Echinococcus multilocularis neuropeptide receptor 0.0056 0.0514 0.0568
Trichomonas vaginalis sugar transport protein, putative 0.0029 0.0217 0.0956
Onchocerca volvulus 0.0056 0.0514 0.3025
Brugia malayi Dopamine receptor protein 2 0.0056 0.0514 0.2218
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Schistosoma mansoni hypothetical protein 0.0039 0.0329 0.0421
Schistosoma mansoni cpg binding protein 0.0031 0.0234 0.0293
Brugia malayi beta-lactamase family protein 0.004 0.0338 0.1434
Schistosoma mansoni myosin xvIII 0.0056 0.0514 0.067
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0016 0.0049
Onchocerca volvulus Putative nachr subunit 0.0077 0.0757 0.4566
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0064 0.0611 0.1908
Loa Loa (eye worm) hypothetical protein 0.0035 0.0279 0.1173
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0217 0.0956
Onchocerca volvulus 0.0046 0.0409 0.2359
Echinococcus multilocularis allatostatin A receptor 0.0056 0.0514 0.0568
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0413 0.2537
Onchocerca volvulus 0.0056 0.0514 0.3025
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.0512 0.0773
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.021 0.2264 0.2563
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0514 0.0568
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0338 0.1208
Echinococcus multilocularis pantothenate kinase 4 0.0076 0.0746 0.0833
Onchocerca volvulus 0.0029 0.0217 0.1134
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0338 0.0433
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0616 0.0807
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.7463 1
Brugia malayi beta-lactamase family protein 0.004 0.0338 0.1434
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0029 0.0217 0.1329
Leishmania major hypothetical protein, conserved 0.0029 0.0217 0.0677
Schistosoma mansoni nAChR subunit 0.0031 0.0229 0.0287
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0346 0.1527
Onchocerca volvulus 0.0095 0.0963 0.5871
Schistosoma mansoni glucose transport protein 0.021 0.2264 0.3019
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0064 0.0611 0.1908
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0217 0.027
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Brugia malayi Sugar transporter family protein 0.021 0.2264 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0432 0.1853
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0514 0.0568
Brugia malayi Dopamine receptor protein 1 0.0056 0.0514 0.2218
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0077 0.0757 0.3298
Onchocerca volvulus 0.0056 0.0514 0.3025
Entamoeba histolytica pantothenate kinase 1, putative 0.0076 0.0746 0.771
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0046 0.0409 0.1752
Loa Loa (eye worm) neuropeptide F receptor 0.0056 0.0514 0.2218
Echinococcus granulosus hypothetical protein 0.0056 0.0514 0.067
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0077 0.0757 0.0996
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0217 0.027
Loa Loa (eye worm) hypothetical protein 0.005 0.045 0.1933
Schistosoma mansoni hypothetical protein 0.0039 0.0329 0.0421
Onchocerca volvulus 0.0047 0.0414 0.2388
Schistosoma mansoni hypothetical protein 0.0033 0.0258 0.0326
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.32 1
Onchocerca volvulus 0.0029 0.0217 0.1134
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0109 0.0339
Leishmania major glucose transporter, lmgt1 0.0065 0.0621 0.1939
Echinococcus multilocularis cpg binding protein 0.0031 0.0234 0.0249
Schistosoma mansoni amine GPCR 0.0056 0.0514 0.067
Schistosoma mansoni hypothetical protein 0.0015 0.0056 0.0054
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0031 0.0229 0.0244
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0621 0.1939
Schistosoma mansoni acetylcholine receptor-related 0.0031 0.0229 0.0287
Onchocerca volvulus 0.0031 0.0229 0.1215
Echinococcus multilocularis sex peptide receptor 0.0056 0.0514 0.0568
Echinococcus granulosus neuropeptide s receptor 0.0056 0.0514 0.067
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0413 0.0534
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0258 0.0921
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0077 0.0757 0.3298
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0063 0.0596 0.6129
Onchocerca volvulus 0.0056 0.0514 0.3025
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0077 0.0757 0.0996
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0217 0.0894
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0514 0.067
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0038 0.0135
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0513 0.0775
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.2264 0.3019
Loa Loa (eye worm) hypothetical protein 0.0035 0.0279 0.1173
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Brugia malayi hypothetical protein 0.0056 0.0514 0.2218
Echinococcus multilocularis g protein coupled receptor 0.0056 0.0514 0.0568
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0217 0.0894
Echinococcus granulosus tumor protein p63 0.0326 0.3594 0.4805
Onchocerca volvulus 0.0029 0.0215 0.1123
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0063 0.0596 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Schistosoma mansoni neuropeptide F-like receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0056 0.0514 0.2218
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0046 0.0409 0.1752
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.002 0.0109 0.0339
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0621 0.1939
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0414 0.2541
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0414 0.2541
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0512 0.226
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0414 0.4205
Schistosoma mansoni growth hormone secretagogue receptor 0.0056 0.0514 0.067
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0038 0.0233
Trypanosoma brucei pantothenate kinase subunit, putative 0.0078 0.0768 0.24
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.021 0.2264 0.2563
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0257 0.2799 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0409 0.1752
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0514 0.067
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0145 0.0577
Echinococcus multilocularis solute carrier family 22 0.0029 0.0217 0.0229
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Onchocerca volvulus 0.0152 0.1613 1
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0038 0.0167
Toxoplasma gondii sugar transporter ST1 0.0029 0.0217 0.0327
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0889 0.0996
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0065 0.0617 0.0932
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0621 0.274
Schistosoma mansoni opsin-like receptor 0.0056 0.0514 0.067
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0077 0.0757 0.0845
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0077 0.0757 0.0845
Echinococcus multilocularis nAChR subunit 0.0046 0.0409 0.0449
Toxoplasma gondii peptidylprolyl isomerase 0.0064 0.0611 0.0922
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Brugia malayi pantothenate kinase family protein 0.0076 0.0746 0.3249
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0514 0.0568
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.0512 0.1599
Schistosoma mansoni neurotransmitter gated ion channel 0.0031 0.0229 0.0287
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0016 0.0056
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0621 0.274
Loa Loa (eye worm) beta-lactamase 0.004 0.0338 0.1434
Onchocerca volvulus 0.0152 0.1613 1
Echinococcus granulosus solute carrier family 22 0.0029 0.0217 0.027
Onchocerca volvulus 0.0029 0.0217 0.1134
Plasmodium vivax hypothetical protein, conserved 0.004 0.0338 0.0323
Plasmodium falciparum pantothenate kinase 1, putative 0.0076 0.0746 0.0732
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Schistosoma mansoni protein kinase 0.0065 0.0616 0.0807
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.1452 0.4538
Echinococcus granulosus cpg binding protein 0.0031 0.0234 0.0293
Echinococcus multilocularis neuropeptide Y receptor 0.0056 0.0514 0.0568
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0038 0.0135
Echinococcus multilocularis protein patched 0.0041 0.0346 0.0376
Onchocerca volvulus 0.0029 0.0217 0.1134
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0064 0.0611 0.6278
Schistosoma mansoni glucose transporter 0.0029 0.0217 0.027
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.2264 0.3019
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0038 0.0135
Brugia malayi lysyl-tRNA synthetase 0.0047 0.0413 0.1769
Mycobacterium ulcerans integral membrane transport protein 0.0029 0.0217 0.1329
Echinococcus granulosus glycine receptor subunit alpha 1 0.0077 0.0757 0.0996
Echinococcus multilocularis neuropeptide s receptor 0.0056 0.0514 0.0568
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0056 0.0514 0.2218
Schistosoma mansoni amine GPCR 0.0056 0.0514 0.067
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0077 0.0757 0.0996
Mycobacterium ulcerans beta-lactamase 0.004 0.0338 0.2075
Brugia malayi hypothetical protein 0.0031 0.0229 0.095
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Schistosoma mansoni nAChR subunit 0.0077 0.0757 0.0996
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0031 0.0229 0.0287
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0963 0.108
Loa Loa (eye worm) pantothenate kinase 0.0076 0.0746 0.3249
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.021 0.2264 0.2563
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0065 0.0616 0.0807
Brugia malayi Serotonin receptor 0.0056 0.0514 0.2218
Trypanosoma brucei glucose transporter 1E 0.0065 0.0621 0.1939
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0889 0.3885
Brugia malayi major facilitator superfamily protein 0.0029 0.0217 0.0894
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0339 0.3737 0.3727
Schistosoma mansoni cpg binding protein 0.0029 0.0215 0.0267
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0077 0.0757 0.0845
Loa Loa (eye worm) hypothetical protein 0.004 0.0338 0.1434
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0038 0.0167
Loa Loa (eye worm) hypothetical protein 0.0048 0.0425 0.182
Echinococcus granulosus tachykinin peptides receptor 99D 0.0056 0.0514 0.067
Brugia malayi hypothetical protein 0.0056 0.0514 0.2218
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0229 0.095
Echinococcus multilocularis dro:myosuppressin receptor 0.0056 0.0514 0.0568
Plasmodium vivax proline--tRNA ligase, putative 0.0073 0.0715 0.07
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0715 0.2234
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0056 0.0514 0.0568
Leishmania major glucose transporter/membrane transporter D2, putative 0.0065 0.0621 0.1939
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0414 0.6942
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0514 0.0568
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0616 0.0685
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0077 0.0757 0.3298
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Brugia malayi GnHR receptor homolog 0.0056 0.0514 0.2218
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0963 0.1272
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0621 0.274
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0077 0.0757 0.0845
Plasmodium falciparum calcium-dependent protein kinase 2 0.0065 0.0617 0.0602
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0414 0.2541
Echinococcus granulosus G protein coupled receptor 139 0.0056 0.0514 0.067
Brugia malayi hypothetical protein 0.0056 0.0514 0.2218
Brugia malayi Sugar transporter family protein 0.0029 0.0217 0.0894
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0047 0.0413 0.1826
Brugia malayi larval opioid receptor 0.0056 0.0514 0.2218
Leishmania major myo-inositol/proton symporter (MIT) 0.0029 0.0217 0.0677
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0621 0.1939
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.004 0.0333 0.1191
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0038 0.0099
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0616 0.0807
Onchocerca volvulus 0.004 0.0338 0.1906
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0348 0.1088
Brugia malayi Cytochrome P450 family protein 0.0023 0.0145 0.0577
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Schistosoma mansoni nAChR subunit 0.0031 0.0229 0.0287
Onchocerca volvulus 0.0056 0.0514 0.3025
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0175 0.0709
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0047 0.0413 0.6932
Schistosoma mansoni opsin-like receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0031 0.0229 0.095
Echinococcus multilocularis neuropeptides capa receptor 0.0056 0.0514 0.0568
Plasmodium vivax pantothenate kinase, putative 0.0076 0.0746 0.0732
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0077 0.0757 0.3298
Echinococcus multilocularis calcium dependent protein kinase 0.006 0.0566 0.0627
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0029 0.0217 0.0677
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0046 0.0409 0.1752
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0056 0.0514 0.0568
Echinococcus granulosus biogenic amine 5HT receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus granulosus neuropeptide Y receptor 0.0056 0.0514 0.067
Echinococcus multilocularis G-protein coupled receptor, putative 0.0056 0.0514 0.0568
Trypanosoma brucei protein kinase, putative 0.0055 0.0512 0.1599
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0338 0.1208
Plasmodium vivax sugar transporter, putative 0.0029 0.0217 0.0201
Onchocerca volvulus Fumble homolog 0.0076 0.0746 0.4497
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0065 0.0617 0.0602
Loa Loa (eye worm) hypothetical protein 0.0095 0.0963 0.4212
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0077 0.0757 0.0996
Echinococcus multilocularis fmrfamide receptor 0.0056 0.0514 0.0568
Echinococcus multilocularis serotonin receptor 0.0056 0.0514 0.0568
Trypanosoma brucei glucose transporter, putative 0.0065 0.0621 0.1939
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Echinococcus multilocularis G protein coupled receptor 139 0.0056 0.0514 0.0568
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0889 0.1173
Loa Loa (eye worm) hypothetical protein 0.004 0.0338 0.1434
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0621 0.1939
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0889 0.3885
Brugia malayi MAP kinase sur-1 0.0055 0.0512 0.2206
Echinococcus granulosus neuropeptides capa receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus granulosus solute carrier family 22 0.0029 0.0217 0.027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0514 0.067
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0628 0.2774
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.0038 0.0057
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0038 0.0118
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Mycobacterium ulcerans hypothetical protein 0.0154 0.1629 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.1452 0.4538
Brugia malayi Cation transporter family protein 0.0152 0.1613 0.7104
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0783 0.8791 1
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0285 0.0892
Schistosoma mansoni hypothetical protein 0.0529 0.5895 0.7894
Schistosoma mansoni biogenic amine receptor 0.0056 0.0514 0.067
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0621 0.274
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0333 0.5587
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0621 0.274
Plasmodium falciparum proline--tRNA ligase 0.0073 0.0715 0.07
Trichomonas vaginalis conserved hypothetical protein 0.021 0.2264 1
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0031 0.0229 0.095
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0014 0.0038 0.0635
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0014 0.0038 0.0233
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0217 0.0894
Brugia malayi hypothetical protein 0.0056 0.0514 0.2218
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0056 0.0514 0.0568
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0038 0.0118
Onchocerca volvulus 0.0056 0.0514 0.3025
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0038 0.0135
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0348 0.1088
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0217 0.0327
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0346 0.1468
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0414 0.4205
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0338 0.1434
Schistosoma mansoni nAChR subunit 0.0077 0.0757 0.0996
Loa Loa (eye worm) G-protein coupled receptor 0.0056 0.0514 0.2218
Loa Loa (eye worm) hypothetical protein 0.0035 0.0279 0.1173
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0963 0.1272
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.32 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0963 0.4214
Brugia malayi Melatonin receptor type 1A 0.0056 0.0514 0.2218
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0056 0.0514 0.067
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0078 0.0768 0.24
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0432 0.1853
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0038 0.0099
Schistosoma mansoni hypothetical protein 0.021 0.2264 0.3019
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0056 0.0179
Mycobacterium ulcerans sugar transporter 0.0029 0.0217 0.1329
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0038 0.0118
Schistosoma mansoni protein kinase 0.0065 0.0616 0.0807
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0056 0.0514 0.067
Schistosoma mansoni glucose transport protein 0.021 0.2264 0.3019
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0963 0.4214
Leishmania major lysyl-tRNA synthetase, putative 0.0047 0.0413 0.1292
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Schistosoma mansoni nAChR subunit 0.0077 0.0757 0.0996
Brugia malayi hypothetical protein 0.0056 0.0514 0.2218
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Schistosoma mansoni histamine h1 receptor 0.0056 0.0514 0.067
Brugia malayi Cation transporter family protein 0.0077 0.0757 0.3298
Onchocerca volvulus 0.004 0.0338 0.1906
Echinococcus granulosus nAChR subunit 0.0046 0.0409 0.0529
Mycobacterium leprae conserved hypothetical protein 0.004 0.0338 0.567
Loa Loa (eye worm) hypothetical protein 0.0046 0.0409 0.1752
Brugia malayi CXXC zinc finger family protein 0.0029 0.0215 0.0886
Onchocerca volvulus 0.0031 0.0229 0.1215
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.0512 0.2206
Brugia malayi Cation transporter family protein 0.0077 0.0757 0.3298
Loa Loa (eye worm) GABA receptor subunit 0.0046 0.0409 0.1752
Schistosoma mansoni hypothetical protein 0.0056 0.0514 0.067
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Schistosoma mansoni biogenic amine receptor 0.0056 0.0514 0.067
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0056 0.0514 0.0568
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.1629 0.5822
Loa Loa (eye worm) hypothetical protein 0.0046 0.0409 0.1752
Toxoplasma gondii protein kinase, putative 0.0592 0.6619 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0514 0.0568
Mycobacterium tuberculosis Conserved protein 0.004 0.0338 0.1208
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0056 0.0054
Trypanosoma brucei glucose transporter 2A 0.0065 0.0621 0.1939
Brugia malayi beta-lactamase 0.004 0.0338 0.1434
Loa Loa (eye worm) hypothetical protein 0.0047 0.0414 0.1772
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0348 0.1536
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0038 0.0135
Trypanosoma brucei glucose transporter, putative 0.0065 0.0621 0.1939
Echinococcus granulosus neuropeptide receptor A26 0.0056 0.0514 0.067
Schistosoma mansoni pantothenate kinase 0.0076 0.0746 0.0981
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0338 0.1208
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0064 0.0611 0.1908
Loa Loa (eye worm) hypothetical protein 0.0047 0.0413 0.1769
Loa Loa (eye worm) hypothetical protein 0.0051 0.0462 0.1987
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0056 0.0514 0.2218
Brugia malayi sulfakinin receptor protein 0.0056 0.0514 0.2218
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0014 0.0038 0.0233
Trypanosoma cruzi glucose transporter, putative 0.0029 0.0217 0.0677
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0016 0.0262
Brugia malayi AKH receptor 0.0056 0.0514 0.2218
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0077 0.0757 0.0996
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0152 0.1613 0.2145
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0077 0.0757 0.0845
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Brugia malayi Tachykinin-like peptides receptor 99D 0.0056 0.0514 0.2218
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0514 0.067
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0596 0.078
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0038 0.0099
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0889 0.1173
Brugia malayi hypothetical protein 0.0031 0.0229 0.095
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0134 0.2978
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0279 0.0264
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0346 0.0443
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.004 0.0333 0.1191
Schistosoma mansoni protein kinase 0.0065 0.0616 0.0807
Echinococcus multilocularis g protein coupled receptor 0.0056 0.0514 0.0568
Echinococcus multilocularis neuropeptide FF receptor 2 0.0056 0.0514 0.0568
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0031 0.0229 0.095
Brugia malayi hypothetical protein 0.0056 0.0514 0.2218
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0014 0.0038 0.0233
Entamoeba histolytica hypothetical protein 0.0047 0.0413 0.4198
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0339 0.3737 0.5646
Schistosoma mansoni pantothenate kinase 0.0076 0.0746 0.0981
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0217 0.0956
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0077 0.0757 0.0845
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0038 0.0233
Brugia malayi neuropeptide F receptor 0.0056 0.0514 0.2218
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0217 0.0956
Leishmania major glucose transporter, lmgt2 0.0065 0.0621 0.1939
Schistosoma mansoni neuropeptide receptor 0.0056 0.0514 0.067
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0065 0.0617 0.0932
Loa Loa (eye worm) ACC-1 protein 0.0077 0.0757 0.3298
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0338 0.1208
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Brugia malayi major facilitator superfamily protein 0.0029 0.0217 0.0894
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0014 0.0038 0.0635
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0279 0.6632
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0134 0.0823
Trypanosoma brucei glucose transporter, putative 0.0065 0.0621 0.1939
Loa Loa (eye worm) hypothetical protein 0.0065 0.0616 0.2672
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0056 0.0514 0.067
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0047 0.0413 0.2537
Trypanosoma brucei glucose transporter, putative 0.0065 0.0621 0.1939
Brugia malayi Sugar transporter family protein 0.0029 0.0217 0.0894
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0038 0.0118
Schistosoma mansoni alpha-1 adrenergic receptor 0.0056 0.0514 0.067
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0217 0.0229
Onchocerca volvulus 0.0029 0.0217 0.1134
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0077 0.0757 0.0996
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0056 0.0514 0.2218
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0031 0.0229 0.0244
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0414 0.6942
Giardia lamblia Sugar-proton symporter 0.0029 0.0217 0.2751
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0038 0.003
Plasmodium vivax CDK-related protein kinase 6, putative 0.089 1 1
Echinococcus multilocularis fmrfamide receptor 0.0056 0.0514 0.0568
Onchocerca volvulus 0.0077 0.0757 0.4566
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0014 0.0038 0.0233
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0056 0.0514 0.067
Schistosoma mansoni hypothetical protein 0.0417 0.4627 0.6192
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0056 0.0514 0.067
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0065 0.0617 0.0602
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0588 0.0769
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0414 0.1479
Plasmodium falciparum hexose transporter 0.021 0.2264 0.2252
Trichomonas vaginalis rotamase, putative 0.0066 0.0628 0.2774
Schistosoma mansoni patched 1 0.0041 0.0346 0.0443
Onchocerca volvulus 0.0077 0.0757 0.4566
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Loa Loa (eye worm) oxidoreductase 0.0014 0.0038 0.0099
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Trypanosoma cruzi hexose transporter 0.0065 0.0621 0.1939
Loa Loa (eye worm) hypothetical protein 0.0095 0.0963 0.4212
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.002 0.0109 0.4625
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0414 0.1772
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0715 0.2234
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Trichomonas vaginalis pantothenate kinase, putative 0.0076 0.0746 0.3296
Toxoplasma gondii lysine-tRNA ligase 0.0047 0.0413 0.0625
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0514 0.067
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Echinococcus granulosus solute carrier family 22 0.0029 0.0217 0.027
Onchocerca volvulus 0.0029 0.0217 0.1134
Echinococcus multilocularis protein dispatched 1 0.0047 0.0411 0.0451
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0152 0.1613 0.2145
Echinococcus multilocularis glycine receptor subunit beta 0.0077 0.0757 0.0845
Onchocerca volvulus 0.0029 0.0217 0.1134
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0338 0.2075
Echinococcus granulosus serotonin receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0077 0.0757 0.3298
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Toxoplasma gondii pantothenate kinase 0.0032 0.0247 0.0373
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0065 0.0617 0.0602
Brugia malayi G protein-coupled receptor 0.0056 0.0514 0.2218
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0056 0.0514 0.067
Onchocerca volvulus 0.0046 0.0409 0.2359
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0338 0.1493
Leishmania major protein kinase, putative 0.0065 0.0616 0.1927
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0064 0.0611 0.1908
Loa Loa (eye worm) hypothetical protein 0.0046 0.0409 0.1752
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0414 0.2541
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0038 0.0118
Trichomonas vaginalis pantothenate kinase, putative 0.0076 0.0746 0.3296
Echinococcus multilocularis nAChR subunit 0.0077 0.0757 0.0845
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0514 0.067
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0047 0.0413 0.1292
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0012 0.0016 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0514 0.067
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0029 0.0217 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0348 0.1088
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0279 0.0998
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0056 0.0179
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0031 0.0229 0.0244
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0621 0.1939
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0077 0.0757 0.3298
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0229 0.095
Mycobacterium ulcerans hypothetical protein 0.004 0.0338 0.2075
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0016 0.0049
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0056 0.0514 0.2218
Toxoplasma gondii fumble protein 0.0076 0.0746 0.1127
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0512 0.1599
Plasmodium falciparum lysine--tRNA ligase 0.0047 0.0413 0.0398
Brugia malayi excitatory GABA receptor EXP-1A 0.0077 0.0757 0.3298
Onchocerca volvulus 0.0048 0.0425 0.2457
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0514 0.0568
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0038 0.0135
Loa Loa (eye worm) hypothetical protein 0.004 0.0338 0.1434
Echinococcus granulosus GPCR family 2 0.0015 0.0056 0.0054
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0056 0.0514 0.067
Leishmania major hypothetical protein, conserved 0.004 0.0338 0.1057
Toxoplasma gondii hypothetical protein 0.0047 0.0417 0.063
Trypanosoma cruzi sugar transporter, putative 0.0029 0.0217 0.0677
Toxoplasma gondii ABC1 family protein 0.004 0.0338 0.0511
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0338 0.0433
Schistosoma mansoni neuropeptide receptor 0.0056 0.0514 0.067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0889 0.1173
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0029 0.0217 0.0774
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Mycobacterium tuberculosis Conserved protein 0.004 0.0338 0.1208
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.0512 0.1599
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0056 0.0514 0.0568
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0038 0.0118
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0038 0.0118
Schistosoma mansoni hypothetical protein 0.0015 0.0056 0.0054
Onchocerca volvulus 0.0089 0.0892 0.5424
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0514 0.067
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0338 0.1493
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Schistosoma mansoni hypothetical protein 0.0056 0.0514 0.067
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0046 0.0409 0.0529
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0077 0.0757 0.3298
Schistosoma mansoni sugar transporter 0.0029 0.0217 0.027
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.7463 0.8487
Brugia malayi hypothetical protein 0.0056 0.0514 0.2218
Trichomonas vaginalis pantothenate kinase, putative 0.0076 0.0746 0.3296
Loa Loa (eye worm) hypothetical protein 0.0035 0.0279 0.1173
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0014 0.0038 0.0233
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0077 0.0757 0.0845
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0414 0.1294
Loa Loa (eye worm) hypothetical protein 0.0035 0.0279 0.1173
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Echinococcus granulosus geminin 0.0529 0.5895 0.7894
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0217 0.027
Echinococcus granulosus glycine receptor subunit beta 0.0077 0.0757 0.0996
Echinococcus granulosus g protein coupled receptor 0.0056 0.0514 0.067
Echinococcus multilocularis expressed protein 0.0066 0.0628 0.0698
Brugia malayi putative neuropeptide receptor 0.0056 0.0514 0.2218
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0066 0.0628 0.2724
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.045 0.1407
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0056 0.0514 0.0568
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0056 0.0514 0.067
Schistosoma mansoni hypothetical protein 0.0056 0.0514 0.067
Echinococcus granulosus orexin receptor type 2 0.0056 0.0514 0.067
Onchocerca volvulus 0.0056 0.0514 0.3025
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0056 0.0514 0.2218
Onchocerca volvulus 0.004 0.0338 0.1906
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus multilocularis glycine receptor subunit beta 0.0077 0.0757 0.0845
Schistosoma mansoni adenoreceptor 0.0056 0.0514 0.067
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0217 0.0894
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0077 0.0757 0.0845
Mycobacterium ulcerans acetyl-CoA synthetase 0.0014 0.0038 0.0233
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0512 0.226
Echinococcus multilocularis lysyl tRNA synthetase 0.0047 0.0413 0.0453
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0109 0.0339
Schistosoma mansoni neuropeptide receptor 0.0056 0.0514 0.067
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.2264 0.3019
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0616 0.0685
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Echinococcus granulosus glycine receptor subunit beta 0.0077 0.0757 0.0996
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0056 0.0514 0.067
Echinococcus multilocularis neuropeptides capa receptor 0.0056 0.0514 0.0568
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0338 0.0433
Loa Loa (eye worm) hypothetical protein 0.0122 0.1265 0.5558
Loa Loa (eye worm) sugar transporter 0.021 0.2264 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0038 0.0135
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0038 0.0099
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0432 0.1853
Loa Loa (eye worm) hypothetical protein 0.0014 0.0038 0.0099
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0016 0.0096
Entamoeba histolytica hypothetical protein 0.0046 0.0409 0.4157
Echinococcus granulosus lysyl tRNA synthetase 0.0047 0.0413 0.0534
Onchocerca volvulus 0.0056 0.0514 0.3025
Loa Loa (eye worm) hypothetical protein 0.004 0.0338 0.1434
Schistosoma mansoni biogenic amine receptor 0.0056 0.0514 0.067
Schistosoma mansoni neuropeptide f receptor 76f 0.0056 0.0514 0.067
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0346 0.0376
Loa Loa (eye worm) melatonin receptor type 1A 0.0056 0.0514 0.2218
Trichomonas vaginalis rotamase, putative 0.0064 0.0611 0.2696
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0063 0.0596 0.078
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0889 0.1173
Schistosoma mansoni cpg binding protein 0.0031 0.0234 0.0293
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0338 0.1057
Onchocerca volvulus 0.0056 0.0514 0.3025
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.0616 0.2722
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Schistosoma mansoni lysyl-tRNA synthetase 0.0047 0.0413 0.0534
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0077 0.0757 0.0845
Echinococcus multilocularis g protein coupled receptor 0.0056 0.0514 0.0568
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0889 0.1173
Schistosoma mansoni hypothetical protein 0.0056 0.0514 0.067
Brugia malayi hypothetical protein 0.0031 0.0229 0.095
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0014 0.0038 0.0635
Echinococcus granulosus microtubule associated protein 2 0.0667 0.7463 1
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0217 0.0956
Giardia lamblia Hexose transporter 0.0029 0.0217 0.2751
Onchocerca volvulus 0.0056 0.0514 0.3025
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0065 0.0616 0.1927
Loa Loa (eye worm) hypothetical protein 0.0152 0.1613 0.7104
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0512 0.1599
Brugia malayi hypothetical protein 0.0029 0.0217 0.0894
Echinococcus granulosus General substrate transporter 0.018 0.1929 0.257
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0258 0.1078
Onchocerca volvulus 0.0152 0.1613 1
Brugia malayi follicle stimulating hormone receptor 0.0056 0.0514 0.2218
Schistosoma mansoni nAChR subunit 0.0077 0.0757 0.0996
Trichomonas vaginalis pantothenate kinase, putative 0.0076 0.0746 0.3296
Plasmodium falciparum calcium-dependent protein kinase 1 0.0065 0.0617 0.0602
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0077 0.0757 0.3298
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Loa Loa (eye worm) hypothetical protein 0.0033 0.0258 0.1078
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0016 0.0024
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0056 0.0514 0.2218
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.0038 0.0057
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0077 0.0757 0.0996
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0016 0.0049
Entamoeba histolytica protein kinase, putative 0.0065 0.0616 0.6341
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0621 0.274
Loa Loa (eye worm) hypothetical protein 0.0046 0.0409 0.1752
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0414 0.1772
Schistosoma mansoni acetylcholine receptor subunit beta 0.0031 0.0229 0.0287
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0056 0.0514 0.0568
Plasmodium vivax lysine--tRNA ligase, putative 0.0047 0.0413 0.0398
Loa Loa (eye worm) hypothetical protein 0.0063 0.0596 0.2583
Brugia malayi neuropeptide F receptor 0.0056 0.0514 0.2218
Plasmodium falciparum calcium-dependent protein kinase 3 0.0065 0.0617 0.0602
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0514 0.067
Onchocerca volvulus Putative transporter 0.0029 0.0217 0.1134
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Onchocerca volvulus 0.0029 0.0217 0.1134
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.0512 0.679
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0056 0.0514 0.0568
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0038 0.0118
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0621 0.1939
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0065 0.0616 0.2672
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0217 0.0956
Schistosoma mansoni amine GPCR 0.0056 0.0514 0.067
Brugia malayi G-protein coupled receptor 0.0056 0.0514 0.2218
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0046 0.0409 0.0529
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0065 0.0616 0.0685
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0031 0.0229 0.0287
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0073 0.0715 0.108
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.098 0.1295
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0066 0.0628 0.2724
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0077 0.0757 0.0996
Onchocerca volvulus 0.0056 0.0514 0.3025
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Loa Loa (eye worm) hypothetical protein 0.0048 0.0432 0.1853
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0056 0.0514 0.067
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0063 0.0596 0.2583
Loa Loa (eye worm) neuropeptide F receptor 0.0056 0.0514 0.2218
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0338 0.1493
Leishmania major pantothenate kinase subunit, putative 0.0078 0.0768 0.24
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0056 0.0514 0.0568
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0338 0.1434
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0616 0.0807
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.0512 0.0666
Onchocerca volvulus 0.0056 0.0514 0.3025
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.0512 0.1599
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0258 0.0921
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0279 0.0264
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0038 0.0099
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0077 0.0757 0.3298
Brugia malayi hypothetical protein 0.0056 0.0514 0.2218
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0038 0.0233
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0279 0.1715
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0016 0.0049
Onchocerca volvulus 0.0029 0.0217 0.1134
Loa Loa (eye worm) acetylcholine receptor protein 0.0031 0.0229 0.095
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0065 0.0616 0.2672
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Echinococcus multilocularis solute carrier family 22 0.0029 0.0217 0.0229
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus granulosus g protein coupled receptor 0.0056 0.0514 0.067
Trichomonas vaginalis pantothenate kinase, putative 0.0076 0.0746 0.3296
Echinococcus granulosus 7tm_1 domain containing protein 0.0056 0.0514 0.067
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0056 0.0514 0.0568
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0414 0.1294
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0047 0.0413 0.1292
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0338 0.1493
Echinococcus multilocularis orexin receptor type 2 0.0056 0.0514 0.0568
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus granulosus tm gpcr rhodopsin 0.0056 0.0514 0.067
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0056 0.0514 0.0568
Echinococcus granulosus solute carrier family 22 0.0029 0.0217 0.027
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0056 0.0046
Brugia malayi Serotonin receptor 0.0056 0.0514 0.2218
Toxoplasma gondii sugar transporter ST2 0.0029 0.0217 0.0327
Echinococcus granulosus allatostatin A receptor 0.0056 0.0514 0.067
Echinococcus multilocularis General substrate transporter 0.018 0.1929 0.2181
Onchocerca volvulus 0.0029 0.0217 0.1134
Loa Loa (eye worm) ACC-1 protein 0.0077 0.0757 0.3298
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0077 0.0757 0.3298
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0258 0.0921
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0217 0.0201
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0056 0.0514 0.2218
Brugia malayi hypothetical protein 0.0056 0.0514 0.2218
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0512 0.226
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0038 0.0135
Echinococcus granulosus fmrfamide receptor 0.0056 0.0514 0.067
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0038 0.0135
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus granulosus glycine receptor subunit alpha 1 0.0077 0.0757 0.0996
Loa Loa (eye worm) LGC-31 protein 0.0077 0.0757 0.3298
Loa Loa (eye worm) hypothetical protein 0.0029 0.0217 0.0894
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.0038 0.0235
Echinococcus granulosus dro:myosuppressin receptor 0.0056 0.0514 0.067
Schistosoma mansoni hypothetical protein 0.0015 0.0056 0.0054
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0056 0.0179
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0077 0.0757 0.3298
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0414 0.4205
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.0512 0.0565
Echinococcus granulosus sex peptide receptor 0.0056 0.0514 0.067
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0038 0.0233
Schistosoma mansoni nAChR subunit 0.0077 0.0757 0.0996
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0077 0.0757 0.3298
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0338 0.2075
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0056 0.0514 0.0568
Toxoplasma gondii sugar transporter ST3 0.0029 0.0217 0.0327
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0038 0.0099
Echinococcus multilocularis neuropeptide receptor 0.0056 0.0514 0.0568
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0077 0.0757 0.3298
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0056 0.0046
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0056 0.0514 0.3025
Brugia malayi Trypsin family protein 0.0095 0.0963 0.4212
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0056 0.0514 0.067
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0217 0.0229
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0514 0.067
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0038 0.0025
Entamoeba histolytica protein kinase, putative 0.0065 0.0616 0.6341
Echinococcus granulosus neuropeptide receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0077 0.0757 0.3298
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0038 0.0135
Plasmodium falciparum mitogen-activated protein kinase 2 0.0339 0.3737 0.3727
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0514 0.067
Echinococcus granulosus neuropeptide Y receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) hypothetical protein 0.0077 0.0757 0.3298
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0512 0.0666
Mycobacterium leprae Probable lipase LipE 0.004 0.0338 0.567
Onchocerca volvulus 0.0029 0.0217 0.1134
Echinococcus granulosus calcium dependent protein kinase 0.006 0.0566 0.0739
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0077 0.0757 0.0996
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0038 0.0233
Plasmodium vivax calcium-dependent protein kinase, putative 0.0065 0.0617 0.0602
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0414 0.1294
Echinococcus multilocularis dnaJ subfamily B 0.0417 0.4627 0.5255
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0963 1
Onchocerca volvulus 0.0029 0.0217 0.1134
Brugia malayi putative neuropeptide receptor NPR1 0.0056 0.0514 0.2218
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0338 0.1493
Onchocerca volvulus 0.0056 0.0514 0.3025
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0217 0.0677
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0217 0.0894
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Echinococcus granulosus expressed protein 0.0066 0.0628 0.0822
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0514 0.067
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Echinococcus granulosus rhodopsin orphan GPCR 0.0056 0.0514 0.067
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0056 0.0514 0.067
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Brugia malayi hypothetical protein 0.0056 0.0514 0.2218
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.32 1
Schistosoma mansoni hypothetical protein 0.0529 0.5895 0.7894
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0963 0.1272
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.021 0.2264 0.2563
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0056 0.0514 0.2218
Giardia lamblia Pantothenate kinase 4 0.0076 0.0746 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0065 0.0616 0.2672
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0038 0.0233
Schistosoma mansoni neurotransmitter gated ion channel 0.0046 0.0409 0.0529
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0056 0.0514 0.0568
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0063 0.0596 0.2583
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0065 0.0617 0.0932
Loa Loa (eye worm) hypothetical protein 0.004 0.0338 0.1434
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.021 0.2264 0.3019
Schistosoma mansoni amine GPCR 0.0056 0.0514 0.067
Loa Loa (eye worm) hypothetical protein 0.0056 0.0514 0.2218
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.0512 0.0666
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0065 0.0616 0.0807
Echinococcus granulosus tm gpcr rhodopsin 0.0056 0.0514 0.067
Echinococcus granulosus dnaJ subfamily B 0.0417 0.4627 0.6192
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0056 0.0514 0.067
Schistosoma mansoni neurotransmitter gated ion channel 0.0031 0.0229 0.0287
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0056 0.0054
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.0512 0.1599
Brugia malayi hypothetical protein 0.0031 0.0229 0.095
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0056 0.0514 0.067
Loa Loa (eye worm) hypothetical protein 0.0047 0.0414 0.1772
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0514 0.067
Echinococcus granulosus neuropeptide FF receptor 2 0.0056 0.0514 0.067
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0077 0.0757 0.3298
Echinococcus granulosus g-protein coupled receptor 0.0056 0.0514 0.067
Onchocerca volvulus 0.0056 0.0514 0.3025
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0056 0.0514 0.067
Trypanosoma brucei glucose transporter, putative 0.0065 0.0621 0.1939
Loa Loa (eye worm) hypothetical protein 0.0063 0.0596 0.2583
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Loa Loa (eye worm) hypothetical protein 0.0031 0.0229 0.095
Schistosoma mansoni hypothetical protein 0.0015 0.0056 0.0054
Echinococcus granulosus pantothenate kinase 4 0.0076 0.0746 0.0981
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0215 0.0886
Echinococcus multilocularis rhodopsin orphan GPCR 0.0056 0.0514 0.0568
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0056 0.0514 0.0568
Brugia malayi hypothetical protein 0.0029 0.0217 0.0894
Echinococcus granulosus expressed conserved protein 0.0089 0.0898 0.1184
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0077 0.0757 0.3298
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Echinococcus multilocularis neuropeptide Y receptor 0.0056 0.0514 0.0568
Trypanosoma brucei sugar transporter, putative 0.0029 0.0217 0.0677
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0077 0.0757 0.0996
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0348 0.1088
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0414 0.2541
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0077 0.0757 0.3298
Onchocerca volvulus 0.0029 0.0217 0.1134
Onchocerca volvulus 0.0056 0.0514 0.3025
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0217 0.0956
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0038 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0621 0.274
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Onchocerca volvulus 0.0077 0.0757 0.4566
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0016 0.0096
Schistosoma mansoni sugar transporter 0.0029 0.0217 0.027
Echinococcus granulosus somatostatin receptor 0.0056 0.0514 0.067
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Chlamydia trachomatis lysine--tRNA ligase 0.0047 0.0413 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0217 0.0956
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0063 0.0596 0.078
Schistosoma mansoni hypothetical protein 0.0039 0.0329 0.0421
Echinococcus granulosus glycine receptor subunit alpha 1 0.0077 0.0757 0.0996
Schistosoma mansoni nAChR subunit 0.0077 0.0757 0.0996
Onchocerca volvulus Neuropeptide F receptor homolog 0.0056 0.0514 0.3025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0056 0.0514 0.067
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0056 0.0514 0.067
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0414 0.2541
Echinococcus granulosus neuropeptides capa receptor 0.0056 0.0514 0.067
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.32 1
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0063 0.0596 0.2634
Echinococcus multilocularis tumor protein p63 0.0326 0.3594 0.4078
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0338 0.1057
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0134 1
Toxoplasma gondii propionate-CoA ligase 0.0014 0.0038 0.0057

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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