Detailed information for compound 874726

Basic information

Technical information
  • TDR Targets ID: 874726
  • Name: 4-(4-methoxyphenyl)-6-methyl-1H-pyrimidine-2- thione
  • MW: 232.301 | Formula: C12H12N2OS
  • H donors: 0 H acceptors: 2 LogP: 2.72 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)c1cc(C)nc(n1)S
  • InChi: 1S/C12H12N2OS/c1-8-7-11(14-12(16)13-8)9-3-5-10(15-2)6-4-9/h3-7H,1-2H3,(H,13,14,16)
  • InChiKey: MVSRDCNZGBIDCH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 107072-30-0
  • ZINC00157496
  • 2(1H)-Pyrimidinethione, 4-(methoxyphenyl)-6-methyl-
  • 2-Mercapto-4-(methoxyphenyl)-6-methylpyrimidine
  • 4-(Methoxyphenyl)-6-methyl-2(1H)-pyrimidinethione
  • EU-0003200

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0054 0.0997 0.3278
Loa Loa (eye worm) hypothetical protein 0.0133 0.2873 0.3323
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0017 0.01 0.002
Brugia malayi hypothetical protein 0.0017 0.01 0.002
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0278 0.6375 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0045 0.0767 0.1204
Brugia malayi ABC transporter family protein 0.0017 0.01 0.002
Onchocerca volvulus 0.002 0.0161 0.064
Trichomonas vaginalis AGC family protein kinase 0.0034 0.05 0.0784
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0017 0.01 0.0152
Brugia malayi Carboxylesterase family protein 0.0135 0.293 0.3391
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0045 0.0767 0.0815
Plasmodium vivax plasmepsin V, putative 0.0017 0.0104 0.002
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.013 0.2804 0.4399
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0144 0.007
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Schistosoma mansoni hypothetical protein 0.002 0.0161 0.0078
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0237 0.05
Trichomonas vaginalis conserved hypothetical protein 0.0234 0.5297 0.8309
Brugia malayi hypothetical protein 0.0017 0.0104 0.0024
Entamoeba histolytica multidrug resistance protein, putative 0.0017 0.01 0.0185
Mycobacterium tuberculosis Conserved protein 0.0131 0.2834 1
Brugia malayi Protein kinase domain containing protein 0.0034 0.05 0.0496
Loa Loa (eye worm) multidrug resistance protein 3 0.0054 0.0997 0.1088
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0045 0.0767 0.069
Entamoeba histolytica P-glyco protein 6, putative 0.0054 0.0997 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.2873 0.5335
Echinococcus multilocularis rac serine:threonine kinase 0.0023 0.0245 0.0172
Schistosoma mansoni multidrug resistance protein 0.0054 0.0997 0.0921
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0745 0.1164
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0017 0.0104 0.0024
Schistosoma mansoni acetylcholinesterase 0.0023 0.0237 0.0155
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0045 0.0767 0.0815
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0054 0.0997 0.1563
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0054 0.0997 0.1428
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0237 0.0155
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0237 0.0155
Loa Loa (eye worm) hypothetical protein 0.0017 0.0104 0.0024
Toxoplasma gondii hypothetical protein 0.0085 0.1726 0.3129
Echinococcus multilocularis RUN 0.002 0.0161 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0144 0.0222
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0085 0.1726 0.5948
Mycobacterium leprae conserved hypothetical protein 0.0085 0.1726 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0237 0.0183
Trichomonas vaginalis abcb9, putative 0.0054 0.0997 0.1563
Brugia malayi ABC transporter family protein 0.0017 0.01 0.002
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0144 0.0227
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0144 0.0062
Echinococcus granulosus serine/threonine protein kinase 0.0023 0.0245 0.0192
Onchocerca volvulus 0.0023 0.0237 0.1494
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0767 0.1204
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0054 0.098 0.1068
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0085 0.1726 0.5948
Echinococcus granulosus dna polymerase eta 0.0044 0.0745 0.0788
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0104 0.002
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0135 0.293 0.2871
Loa Loa (eye worm) hypothetical protein 0.0017 0.01 0.002
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0054 0.0997 0.1563
Brugia malayi Pepsin A precursor 0.0017 0.0104 0.0024
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Brugia malayi Doublecortin family protein 0.002 0.0161 0.0092
Echinococcus multilocularis neuroligin 0.0023 0.0237 0.0163
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0104 0.0024
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Trypanosoma brucei multidrug resistance protein E 0.0017 0.01 0.0152
Schistosoma mansoni multidrug resistance protein 0.0054 0.0997 0.0921
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0366 0.8478 1
Entamoeba histolytica hypothetical protein 0.0017 0.01 0.0185
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0045 0.0767 0.069
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0045 0.0767 0.0815
Loa Loa (eye worm) hypothetical protein 0.0017 0.01 0.002
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0017 0.01 0.0017
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0144 0.0222
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0104 0.002
Loa Loa (eye worm) hypothetical protein 0.0045 0.0767 0.0815
Brugia malayi hypothetical protein 0.0017 0.0104 0.0024
Brugia malayi ABC transporter family protein 0.0017 0.01 0.002
Plasmodium vivax aspartyl proteinase, putative 0.0017 0.0104 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0234 0.5297 0.8309
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0104 0.002
Schistosoma mansoni rab6-interacting 0.002 0.0161 0.0078
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0045 0.0767 0.1204
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0144 0.0073
Echinococcus multilocularis acetylcholinesterase 0.0135 0.293 0.3377
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0144 0.0222
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0161 0.0092
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0017 0.01 0.5
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0032 0.045 0.0436
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0017 0.0104 0.0163
Trypanosoma cruzi Protein kinase B 0.0023 0.0245 0.023
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0144 0.0222
Brugia malayi Carboxylesterase family protein 0.0023 0.0237 0.0183
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0144 0.0053
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0144 0.0161
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0054 0.0997 0.1563
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.013 0.2804 0.2744
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0767 0.1063
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.1726 0.2708
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.013 0.2804 0.3241
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0045 0.0767 0.0796
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0045 0.0767 0.4102
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0054 0.0997 0.107
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0045 0.0767 0.1063
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0161 0.0072
Echinococcus granulosus multidrug resistance protein 1 0.0038 0.0603 0.0619
Loa Loa (eye worm) ABC transporter 0.0017 0.01 0.002
Mycobacterium ulcerans putative regulatory protein 0.0085 0.1726 0.5948
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0161 0.0072
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0045 0.0767 0.1204
Mycobacterium ulcerans putative regulatory protein 0.0085 0.1726 0.5948
Echinococcus granulosus multidrug resistance protein 1 0.0038 0.0603 0.0619
Leishmania major DNA polymerase eta, putative 0.0044 0.0745 0.1027
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0045 0.0767 0.1204
Loa Loa (eye worm) hypothetical protein 0.0135 0.293 0.3391
Loa Loa (eye worm) carboxylesterase 0.0023 0.0237 0.0183
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0144 0.0669
Schistosoma mansoni multidrug resistance protein 0.0017 0.01 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0034 0.05 0.0784
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0144 0.0161
Echinococcus granulosus geminin 0.0166 0.3684 0.4289
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0054 0.0997 0.1563
Loa Loa (eye worm) ABC transporter 0.0017 0.01 0.002
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0054 0.0997 0.1563
Entamoeba histolytica ABC transporter, putative 0.0017 0.01 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0767 0.1204
Loa Loa (eye worm) PDE1B protein 0.0045 0.0767 0.0815
Entamoeba histolytica ATP-binding cassette protein, putative 0.0017 0.01 0.0185
Schistosoma mansoni multidrug resistance protein 0.0017 0.01 0.0017
Trichomonas vaginalis ABC transporter, putative 0.0054 0.0997 0.1563
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Schistosoma mansoni smdr2 0.0054 0.0997 0.0921
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0054 0.0997 0.1563
Loa Loa (eye worm) hypothetical protein 0.0017 0.0104 0.0024
Brugia malayi aspartic protease BmAsp-1, identical 0.0017 0.0104 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0144 0.0222
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Leishmania major hypothetical protein, conserved 0.0045 0.0767 0.1063
Plasmodium falciparum plasmepsin VI 0.0017 0.0104 0.002
Plasmodium falciparum plasmepsin V 0.0017 0.0104 0.002
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0104 0.002
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0045 0.0767 0.069
Schistosoma mansoni polycystin 1-related 0.002 0.0161 0.0078
Plasmodium falciparum plasmepsin IV 0.0017 0.0104 0.002
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0194 0.4338 0.6805
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0144 0.007
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0045 0.0767 0.069
Mycobacterium tuberculosis Toxin MazF3 0.0131 0.2834 1
Echinococcus granulosus BC026374 protein S09 family 0.0023 0.0237 0.0183
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.013 0.2804 0.4399
Schistosoma mansoni lipoxygenase 0.002 0.0161 0.0078
Echinococcus granulosus acetylcholinesterase 0.0135 0.293 0.3391
Leishmania major p-glycoprotein 0.0054 0.0997 0.1428
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0144 0.007
Echinococcus granulosus neuroligin 0.0023 0.0237 0.0183
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0045 0.0767 0.0815
Brugia malayi hypothetical protein 0.0023 0.0237 0.0183
Schistosoma mansoni cathepsin D (A01 family) 0.0017 0.0104 0.002
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.013 0.2804 0.3241
Loa Loa (eye worm) hypothetical protein 0.002 0.0161 0.0092
Trichomonas vaginalis ABC transporter, putative 0.0054 0.0997 0.1563
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0045 0.0767 0.1204
Mycobacterium tuberculosis Possible toxin MazF5 0.0131 0.2834 1
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0045 0.0767 0.0815
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0144 0.0222
Echinococcus granulosus multidrug resistance protein 1 0.0054 0.0997 0.1088
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0045 0.0767 0.069
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0237 0.05
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0045 0.0767 0.1063
Leishmania major DNA polymerase kappa, putative 0.0019 0.0144 0.007
Schistosoma mansoni loxhd1 0.002 0.0161 0.0078
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0767 0.4102
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0045 0.0767 0.0796
Entamoeba histolytica P-glycoprotein 5, putative 0.0054 0.0997 1
Schistosoma mansoni multidrug resistance protein 0.0017 0.01 0.0017
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0045 0.0767 0.1204
Loa Loa (eye worm) ABC transporter 0.0017 0.01 0.002
Trichomonas vaginalis AGC family protein kinase 0.0034 0.05 0.0784
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0017 0.01 0.0152
Echinococcus granulosus dna polymerase kappa 0.0019 0.0144 0.0073
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0054 0.0997 0.107
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0431 0.0637
Brugia malayi Eukaryotic aspartyl protease family protein 0.0017 0.0104 0.0024
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0045 0.0767 0.1063
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0431 0.0527
Loa Loa (eye worm) carboxylesterase 0.0023 0.0237 0.0183
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0054 0.0997 0.1088
Onchocerca volvulus 0.0023 0.0237 0.1494
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0045 0.0767 0.1204
Onchocerca volvulus 0.0023 0.0237 0.1494
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0045 0.0767 0.1204
Mycobacterium ulcerans hypothetical protein 0.0131 0.2834 1
Trichomonas vaginalis abcb9, putative 0.0054 0.0997 0.1563
Plasmodium falciparum plasmepsin IX 0.0017 0.0104 0.002
Entamoeba histolytica protein kinase, putative 0.0032 0.045 0.401
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0161 0.0372
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0133 0.2873 0.3309
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0767 0.1204
Loa Loa (eye worm) hypothetical protein 0.0023 0.0237 0.0183
Loa Loa (eye worm) hypothetical protein 0.0054 0.098 0.1068
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0045 0.0767 0.0796
Trichomonas vaginalis conserved hypothetical protein 0.0234 0.5297 0.8309
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.013 0.2804 0.4399
Toxoplasma gondii aspartyl protease ASP1 0.0017 0.0104 0.0006
Brugia malayi multidrug resistance related protein 1 0.0017 0.01 0.002
Loa Loa (eye worm) hypothetical protein 0.013 0.2804 0.3241
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0104 0.002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Loa Loa (eye worm) hypothetical protein 0.0023 0.0237 0.0183
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0278 0.6375 0.749
Entamoeba histolytica P-glycoprotein 6, putative 0.0017 0.01 0.0185
Giardia lamblia hypothetical protein 0.0045 0.0767 0.2452
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0023 0.0237 0.0183
Entamoeba histolytica protein kinase, putative 0.0034 0.05 0.4558
Entamoeba histolytica ATP-binding cassette protein, putative 0.0017 0.01 0.0185
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0767 0.1204
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0104 0.002
Echinococcus multilocularis nervana 2 0.0021 0.0189 0.0106
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0045 0.0767 0.069
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Echinococcus granulosus nervana 2 0.0021 0.0189 0.0126
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0278 0.6375 1
Entamoeba histolytica P-glycoprotein-2 0.0054 0.0997 1
Brugia malayi ABC transporter transmembrane region family protein 0.0017 0.01 0.002
Trichomonas vaginalis abcb9, putative 0.0054 0.0997 0.1563
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0745 0.1027
Echinococcus granulosus ATP binding cassette sub family B 0.0017 0.01 0.002
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0054 0.0997 0.1563
Echinococcus granulosus multidrug resistance protein 1 0.0054 0.0997 0.1088
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0144 0.0073
Echinococcus granulosus nervana 2 0.0021 0.0189 0.0126
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0104 0.002
Schistosoma mansoni smdr1 0.0017 0.01 0.0017
Plasmodium falciparum plasmepsin VII 0.0017 0.0104 0.002
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0016 0.0083 0.0131
Plasmodium vivax aspartyl protease, putative 0.0017 0.0104 0.002
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0017 0.01 0.0157
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0083 0.0131
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0045 0.0767 0.0796
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0278 0.6375 1
Toxoplasma gondii hypothetical protein 0.0085 0.1726 0.3129
Trichomonas vaginalis AGC family protein kinase 0.0034 0.05 0.0784
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0144 0.0222
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0104 0.002
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0278 0.6375 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0045 0.0767 0.0815
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0278 0.6375 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0278 0.6375 1
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0045 0.0767 0.1199
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0054 0.0997 0.1088
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0021 0.0195 0.0113
Onchocerca volvulus 0.0023 0.0237 0.1494
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0278 0.6375 0.7495
Echinococcus granulosus serine threonine protein kinase nrc 0.0021 0.0195 0.0133
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0366 0.8478 1
Echinococcus granulosus multidrug resistance associated protein 1 0.0017 0.01 0.002
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0237 0.0155
Entamoeba histolytica P-glycoprotein-5 0.0054 0.0997 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0016 0.0083 0.0131
Entamoeba histolytica protein kinase 2, putative 0.0021 0.0195 0.122
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Echinococcus multilocularis multidrug resistance protein 1 0.0054 0.0997 0.107
Loa Loa (eye worm) hypothetical protein 0.0023 0.0237 0.0183
Trichomonas vaginalis taga, putative 0.0054 0.0997 0.1563
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0278 0.6375 1
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0088 0.1795 0.2039
Entamoeba histolytica P-glycoprotein-2 0.0054 0.0997 1
Entamoeba histolytica P-glycoprotein-1 0.0054 0.0997 1
Giardia lamblia Multidrug resistance-associated protein 1 0.0017 0.01 0.0061
Schistosoma mansoni hypothetical protein 0.0166 0.3684 0.3631
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0088 0.1795 0.2023
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0133 0.2873 0.3323
Loa Loa (eye worm) hypothetical protein 0.0085 0.1726 0.1957
Mycobacterium tuberculosis Toxin MazF2 0.0131 0.2834 1
Mycobacterium tuberculosis Toxin MazF6 0.0131 0.2834 1
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0767 0.1063
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0144 0.0053
Mycobacterium ulcerans carboxylesterase, LipT 0.0023 0.0237 0.05
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0017 0.0104 0.0006
Brugia malayi multidrug resistance protein 3 0.0054 0.0997 0.1088
Loa Loa (eye worm) acetylcholinesterase 1 0.0135 0.293 0.3391
Schistosoma mansoni multidrug resistance protein 0.0054 0.0997 0.0921
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0054 0.0997 0.1563
Echinococcus granulosus acetylcholinesterase 0.0135 0.293 0.3391
Loa Loa (eye worm) hypothetical protein 0.0017 0.01 0.002
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0021 0.0189 0.0106
Loa Loa (eye worm) hypothetical protein 0.0045 0.0767 0.0815
Giardia lamblia Kinase, AGC PKA 0.0021 0.0195 0.0399
Entamoeba histolytica PH domain containing protein kinase, putative 0.0023 0.0245 0.1767
Plasmodium vivax aspartyl protease, putative 0.0017 0.0104 0.002
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0054 0.0997 0.107
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0278 0.6375 0.6345
Giardia lamblia Hypothetical protein 0.0045 0.0767 0.2452
Echinococcus multilocularis multidrug resistance protein 1 0.0038 0.0603 0.06
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0767 0.1199
Entamoeba histolytica PH domain containing protein kinase, putative 0.0023 0.0245 0.1767
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0767 0.4102
Entamoeba histolytica ATP-binding cassette protein, putative 0.0017 0.01 0.0185
Trypanosoma brucei p-glycoprotein 0.0017 0.01 0.0152
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0366 0.8478 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0278 0.6375 1
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0144 0.0161
Brugia malayi ABC transporter family protein 0.0054 0.0997 0.1088
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0054 0.0997 0.1088
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0144 0.0222
Echinococcus granulosus multidrug resistance protein 1 0.0054 0.0997 0.1088
Toxoplasma gondii AGC kinase 0.0032 0.045 0.0672
Brugia malayi hypothetical protein 0.002 0.0161 0.0092
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0144 0.0073
Schistosoma mansoni BC026374 protein (S09 family) 0.0023 0.0237 0.0155
Leishmania major cAMP-specific phosphodiesterase, putative 0.0045 0.0767 0.1063
Plasmodium vivax multidrug resistance protein 1, putative 0.0054 0.0997 0.5511
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0054 0.0997 0.1563
Echinococcus multilocularis Glutaredoxin protein 5 0.0021 0.0189 0.0106
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0144 0.0161
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0017 0.0104 0.0024
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0045 0.0767 0.1063
Mycobacterium tuberculosis Possible toxin MazF1 0.0131 0.2834 1
Brugia malayi Carboxylesterase family protein 0.0023 0.0237 0.0183
Echinococcus multilocularis geminin 0.0166 0.3684 0.4277
Echinococcus multilocularis BC026374 protein (S09 family) 0.0023 0.0237 0.0163
Echinococcus multilocularis dna polymerase eta 0.0044 0.0745 0.0769
Plasmodium vivax hypothetical protein, conserved 0.0085 0.1726 1
Schistosoma mansoni DNA polymerase eta 0.0044 0.0745 0.0667
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0021 0.0195 0.0581
Plasmodium falciparum plasmepsin III 0.0017 0.0104 0.002
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0021 0.0195 0.0581
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0045 0.0767 0.0815
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0133 0.2873 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0054 0.0997 0.1563
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0045 0.0767 0.069
Echinococcus multilocularis acetylcholinesterase 0.0135 0.293 0.3377
Trypanosoma brucei rac serine-threonine kinase, putative 0.0034 0.05 0.0779
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0767 0.4102
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0278 0.6375 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0133 0.2873 0.3309
Onchocerca volvulus 0.0023 0.0237 0.1494
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0133 0.2873 0.3323
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0767 0.4102
Trichomonas vaginalis ABC transporter, putative 0.0054 0.0997 0.1563
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0144 0.0227
Trichomonas vaginalis spcc417.12 protein, putative 0.0023 0.0237 0.0372
Brugia malayi aspartic protease BmAsp-2, identical 0.0017 0.0104 0.0024
Echinococcus granulosus Glutaredoxin protein 5 0.0021 0.0189 0.0126
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0054 0.0997 0.1563
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Plasmodium vivax phosphodiesterase gamma, putative 0.0045 0.0767 0.4102
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0144 0.0222
Loa Loa (eye worm) carboxylesterase 0.0135 0.293 0.3391
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0054 0.0997 0.1563
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0045 0.0767 0.1199
Echinococcus granulosus ATP binding cassette sub family B 0.0017 0.01 0.002
Onchocerca volvulus 0.002 0.0161 0.064
Plasmodium falciparum multidrug resistance protein 1 0.0054 0.0997 0.5511
Mycobacterium tuberculosis Possible toxin MazF7 0.0131 0.2834 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0038 0.0603 0.0945
Entamoeba histolytica protein kinase, putative 0.0034 0.05 0.4558
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0767 0.1063
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Echinococcus multilocularis nervana 2 0.0021 0.0189 0.0106
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0278 0.6375 1
Schistosoma mansoni hypothetical protein 0.0166 0.3684 0.3631
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0194 0.4338 0.6754
Plasmodium falciparum GAF domain-related protein, putative 0.0085 0.1726 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0161 0.0092
Echinococcus granulosus para nitrobenzyl esterase 0.0023 0.0237 0.0183
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0045 0.0767 0.0815
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0054 0.0997 0.1563
Onchocerca volvulus 0.0054 0.0997 1
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0767 0.1199
Toxoplasma gondii GAF domain-containing protein 0.0085 0.1726 0.3129
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0054 0.0997 0.1563
Plasmodium vivax aspartyl protease, putative 0.0017 0.0104 0.002
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0017 0.01 0.0152
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0017 0.01 0.0152
Plasmodium falciparum plasmepsin VIII, putative 0.0017 0.0104 0.002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0745 0.0788
Entamoeba histolytica ATP-binding cassette protein, putative 0.0017 0.01 0.0185
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0144 0.0062
Plasmodium falciparum phosphodiesterase delta, putative 0.0045 0.0767 0.4102
Plasmodium falciparum plasmepsin I 0.0017 0.0104 0.002
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0366 0.8478 0.8466
Loa Loa (eye worm) doublecortin family protein 0.002 0.0161 0.0092
Schistosoma mansoni serine/threonine-protein kinase 0.0023 0.0245 0.0163
Trichomonas vaginalis ABC transporter, putative 0.0054 0.0997 0.1563
Brugia malayi P-glycoprotein-like protein 0.0017 0.01 0.002
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.013 0.2804 0.3241
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0017 0.01 0.5
Brugia malayi Carboxylesterase family protein 0.0023 0.0237 0.0183
Plasmodium vivax aspartyl proteinase, putative 0.0017 0.0104 0.002
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0088 0.1795 0.2039
Schistosoma mansoni multidrug resistance protein 0.0017 0.01 0.0017
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0016 0.0083 0.0131
Schistosoma mansoni rab6-interacting 0.002 0.0161 0.0078
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0054 0.0997 0.107
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0161 0.0092
Loa Loa (eye worm) AGC/AKT protein kinase 0.0034 0.05 0.0496
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0054 0.0997 0.1563
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0144 0.0222
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0017 0.01 0.002
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.013 0.2804 0.3227
Toxoplasma gondii aspartyl protease 0.0017 0.0104 0.0006
Entamoeba histolytica P-glycoprotein 6, putative 0.0017 0.01 0.0185
Trichomonas vaginalis AGC family protein kinase 0.0034 0.05 0.0784
Leishmania major hypothetical protein, conserved 0.0045 0.0767 0.1063
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0366 0.8478 1
Plasmodium falciparum plasmepsin II 0.0017 0.0104 0.002
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0021 0.0195 0.0151
Loa Loa (eye worm) hypothetical protein 0.0023 0.0237 0.0183
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0278 0.6375 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0997 0.1088
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0023 0.0245 0.023
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Echinococcus multilocularis multidrug resistance protein 1 0.0054 0.0997 0.107
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0161 0.0372
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Brugia malayi ABC transporter transmembrane region family protein 0.0017 0.01 0.002
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0104 0.002
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0133 0.2873 0.2813
Loa Loa (eye worm) hypothetical protein 0.0135 0.293 0.3391
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0085 0.1726 0.5948
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0767 0.1063
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0054 0.0997 0.1563
Giardia lamblia Multidrug resistance-associated protein 1 0.0017 0.01 0.0061
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0767 0.1063
Plasmodium falciparum plasmepsin X 0.0017 0.0104 0.002
Echinococcus multilocularis ATP binding cassette sub family B 0.0054 0.098 0.105
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Mycobacterium tuberculosis Toxin MazF9 0.0131 0.2834 1
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0017 0.0104 0.0006
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0023 0.0237 0.0163
Schistosoma mansoni serine/threonine-protein kinase 0.0023 0.0245 0.0163
Mycobacterium tuberculosis Possible toxin MazF4 0.0131 0.2834 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0054 0.0997 0.1563
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0021 0.0195 0.0133
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0054 0.0997 0.1563
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0045 0.0767 0.4102
Schistosoma mansoni neuroligin 3 (S09 family) 0.0023 0.0237 0.0155
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0054 0.0997 0.107
Trichomonas vaginalis conserved hypothetical protein 0.0278 0.6375 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0237 0.0183
Echinococcus multilocularis para nitrobenzyl esterase 0.0023 0.0237 0.0163
Loa Loa (eye worm) hypothetical protein 0.0023 0.0237 0.0183
Schistosoma mansoni gliotactin 0.0023 0.0237 0.0155
Brugia malayi Carboxylesterase family protein 0.0135 0.293 0.3391
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0045 0.0767 0.069
Echinococcus granulosus carboxylesterase 5A 0.0135 0.293 0.3391
Schistosoma mansoni multidrug resistance protein 0.0017 0.01 0.0017
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0023 0.0237 0.0372
Brugia malayi hypothetical protein 0.002 0.0161 0.0092
Brugia malayi Carboxylesterase family protein 0.0023 0.0237 0.0183
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0021 0.0189 0.0126
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0054 0.0997 0.1563
Plasmodium falciparum phosphodiesterase gamma, putative 0.0045 0.0767 0.4102
Loa Loa (eye worm) aspartyl protease 6 0.0017 0.0104 0.0024
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0278 0.6375 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0144 0.0222
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0054 0.0997 0.5
Toxoplasma gondii hypothetical protein 0.0234 0.5297 1
Brugia malayi ABC transporter 0.0017 0.01 0.002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Trichomonas vaginalis AGC family protein kinase 0.0034 0.05 0.0784
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0194 0.4338 0.6805
Plasmodium vivax plasmepsin IV, putative 0.0017 0.0104 0.002
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0054 0.0997 0.1724
Giardia lamblia ABC transporter, putative 0.0017 0.01 0.0061
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0767 0.1283
Mycobacterium tuberculosis Carboxylesterase LipT 0.0023 0.0237 0.05
Entamoeba histolytica P-glycoprotein-2, putative 0.0054 0.0997 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0997 0.1088
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0278 0.6375 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0144 0.007
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0278 0.6375 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0278 0.6375 1
Schistosoma mansoni cathepsin D (A01 family) 0.0017 0.0104 0.002
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0054 0.0997 0.1563
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0045 0.0767 0.0815
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0745 0.0788
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0767 0.1063
Trypanosoma brucei unspecified product 0.0019 0.0144 0.0222
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0054 0.0997 0.1724
Echinococcus granulosus RUN 0.002 0.0161 0.0092
Echinococcus multilocularis carboxylesterase 5A 0.0135 0.293 0.3377
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0144 0.0222
Trichomonas vaginalis AGC family protein kinase 0.0034 0.05 0.0784
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0017 0.0104 0.0004
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0054 0.0997 0.1088
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0054 0.0997 0.1088
Giardia lamblia MRP-like ABC transporter 0.0017 0.01 0.0061
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0144 0.0222
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0161 0.0072
Trypanosoma brucei hypothetical protein, conserved 0.0045 0.0767 0.1199
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0161 0.0092
Giardia lamblia DINP protein human, muc B family 0.0019 0.0144 0.0219
Leishmania major DNA polymerase eta, putative 0.0031 0.0431 0.0527
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0054 0.0997 0.1563
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0045 0.0767 0.4102
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0088 0.1795 0.2039
Brugia malayi p70 ribosomal S6 kinase beta 0.0032 0.045 0.0436
Toxoplasma gondii aspartyl protease ASP3 0.0017 0.0104 0.0006
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0045 0.0767 0.1063
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0017 0.0104 0.0024
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0054 0.0997 0.1563
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0278 0.6375 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0144 0.007
Echinococcus granulosus multidrug resistance associated protein 7 0.0017 0.01 0.002
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0278 0.6375 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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