Detailed information for compound 888436

Basic information

Technical information
  • TDR Targets ID: 888436
  • Name: [5-[[4-(3-prop-2-enoxypropanoyl)-1,4-diazepan -1-yl]methyl]furan-2-yl]methyl acetate
  • MW: 364.436 | Formula: C19H28N2O5
  • H donors: 0 H acceptors: 2 LogP: 0.64 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCOCCC(=O)N1CCCN(CC1)Cc1ccc(o1)COC(=O)C
  • InChi: 1S/C19H28N2O5/c1-3-12-24-13-7-19(23)21-9-4-8-20(10-11-21)14-17-5-6-18(26-17)15-25-16(2)22/h3,5-6H,1,4,7-15H2,2H3
  • InChiKey: QXTGBSHRYFBYOM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [5-[[4-(3-allyloxypropanoyl)-1,4-diazepan-1-yl]methyl]-2-furyl]methyl acetate
  • acetic acid [5-[[4-(3-allyloxy-1-oxopropyl)-1,4-diazepan-1-yl]methyl]-2-furyl]methyl ester
  • acetic acid [5-[[4-(3-allyloxypropanoyl)-1,4-diazepan-1-yl]methyl]-2-furyl]methyl ester
  • [5-[[4-(3-prop-2-enoxypropanoyl)-1,4-diazepan-1-yl]methyl]furan-2-yl]methyl ethanoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0319 0.0308
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0667 0.312
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0673 0.4537
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.119 0.5566
Loa Loa (eye worm) MH2 domain-containing protein 0.0131 0.2408 0.4183
Brugia malayi Sugar transporter family protein 0.0117 0.2137 0.3712
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0584 0.0995
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0082 0.1468 0.2551
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0035 0.0561 0.3769
Brugia malayi Sugar transporter family protein 0.0016 0.0202 0.0351
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0319 0.211
Mycobacterium tuberculosis Conserved protein 0.0082 0.1468 0.1458
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0102 0.0479
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0289 0.4235
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Schistosoma mansoni sugar transporter 0.0016 0.0202 0.0351
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0319 0.0308
Mycobacterium ulcerans sugar transporter 0.0016 0.0202 0.0331
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0388 0.0674
Brugia malayi beta-lactamase family protein 0.0082 0.1468 0.2551
Plasmodium vivax CDK-related protein kinase 6, putative 0.0498 0.9443 1
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0202 0.0351
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0102 0.0479
Onchocerca volvulus 0.0016 0.0202 0.0729
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0584 0.0995
Schistosoma mansoni smad 0.0009 0.0057 0.0099
Echinococcus multilocularis smad 0.0009 0.0057 0.0268
Mycobacterium ulcerans glutaminase 0.0306 0.5757 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Loa Loa (eye worm) MH2 domain-containing protein 0.0009 0.0057 0.0099
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0102 0.0479
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0319 0.211
Mycobacterium tuberculosis Probable lipase LipE 0.0082 0.1468 0.1458
Mycobacterium ulcerans hypothetical protein 0.0082 0.1468 0.2535
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0014 0.0163 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.2137 0.3699
Echinococcus granulosus solute carrier family 22 0.0016 0.0202 0.0945
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0584 0.0995
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0036 0.0575 0.0999
Schistosoma mansoni sugar transporter 0.0016 0.0202 0.0351
Trichomonas vaginalis glucose transporter, putative 0.0016 0.0202 0.0331
Echinococcus granulosus solute carrier family 22 0.0016 0.0202 0.0945
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0319 0.0555
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0673 0.4537
Trypanosoma cruzi hexose transporter 0.0036 0.0584 0.3925
Trichomonas vaginalis sugar transport protein, putative 0.0016 0.0202 0.0331
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0102 0.0178
Trichomonas vaginalis penicillin-binding protein, putative 0.0082 0.1468 0.2535
Trypanosoma brucei glucose transporter, putative 0.0036 0.0584 0.3925
Schistosoma mansoni glucose transport protein 0.0117 0.2137 0.3712
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0667 1
Chlamydia trachomatis proline--tRNA ligase 0.0012 0.0124 0.2978
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0022 0.0312 0.0301
Loa Loa (eye worm) hypothetical protein 0.0011 0.0102 0.0178
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.119 0.205
Trichomonas vaginalis penicillin-binding protein, putative 0.0082 0.1468 0.2535
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0102 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0319 0.211
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0319 0.211
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0036 0.0575 0.269
Giardia lamblia Prolyl-tRNA synthetase 0.0035 0.0561 0.8384
Schistosoma mansoni hypothetical protein 0.0117 0.2137 0.3712
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0026 0.0388 0.0654
Echinococcus multilocularis lysyl tRNA synthetase 0.0026 0.0388 0.1815
Trypanosoma brucei DNA damage repair protein, putative 0.0007 0.002 0.0055
Trypanosoma cruzi hypothetical protein, conserved 0.0007 0.002 0.0055
Loa Loa (eye worm) hypothetical protein 0.0007 0.0012 0.0021
Brugia malayi glutaminase DH11.1 0.0306 0.5757 1
Leishmania major DNA polymerase eta, putative 0.0007 0.002 0.0055
Loa Loa (eye worm) hypothetical protein 0.0082 0.1468 0.2551
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.1468 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0102 0.0178
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0102 0.0178
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0319 0.211
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0102 0.0479
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0102 0.0479
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0102 0.0178
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0102 0.0178
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0289 0.0502
Trypanosoma brucei unspecified product 0.0023 0.0319 0.211
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0102 0.0178
Trypanosoma brucei DNA damage repair protein, putative 0.0007 0.002 0.0055
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0016 0.0202 0.685
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0667 0.4495
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0319 0.0555
Leishmania major protein kinase, putative 0.0036 0.0575 0.3865
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0319 0.211
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0007 0.002 0.0013
Echinococcus granulosus Threonyl tRNA synthetase C 0.0007 0.0012 0.0056
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0102 0.0479
Loa Loa (eye worm) hypothetical protein 0.0011 0.0102 0.0178
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0036 0.0575 0.0999
Echinococcus granulosus General substrate transporter 0.0101 0.1821 0.8518
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0035 0.0561 0.8384
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0584 0.3925
Brugia malayi MH1 domain containing protein 0.0009 0.0057 0.0099
Trypanosoma brucei glucose transporter, putative 0.0036 0.0584 0.3925
Giardia lamblia Lysyl-tRNA synthetase 0.0026 0.0388 0.5742
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0102 0.0178
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0035 0.0561 0.0974
Echinococcus granulosus lysyl tRNA synthetase 0.0026 0.0388 0.1815
Toxoplasma gondii protein kinase, putative 0.0331 0.6248 1
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0289 0.0483
Mycobacterium ulcerans lipase LipD 0.0082 0.1468 0.2535
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0102 0.0178
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0117 0.2137 1
Trypanosoma cruzi hexose transporter, putative 0.002 0.0267 0.1751
Trichomonas vaginalis D-aminoacylase, putative 0.0082 0.1468 0.2535
Plasmodium falciparum mitogen-activated protein kinase 2 0.019 0.3524 0.3724
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0035 0.0561 0.0955
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0575 0.269
Plasmodium falciparum proline--tRNA ligase 0.0041 0.0673 0.0701
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0319 0.211
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0319 0.0535
Onchocerca volvulus 0.0016 0.0202 0.0729
Loa Loa (eye worm) hypothetical protein 0.0011 0.0102 0.0178
Plasmodium vivax proline--tRNA ligase, putative 0.0041 0.0673 0.0701
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0584 0.0995
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0667 0.114
Schistosoma mansoni glucose transporter 0.0016 0.0202 0.0351
Mycobacterium tuberculosis Probable lipase LipD 0.0082 0.1468 0.1458
Loa Loa (eye worm) hypothetical protein 0.0035 0.0561 0.0974
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0319 0.0535
Schistosoma mansoni smad1 5 8 and 0.0009 0.0057 0.0099
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0667 0.1158
Loa Loa (eye worm) hypothetical protein 0.0035 0.0561 0.0974
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0035 0.0561 0.0974
Echinococcus granulosus beta LACTamase domain containing family member 0.0082 0.1468 0.6871
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0289 0.1904
Loa Loa (eye worm) sugar transporter 0.0016 0.0202 0.0351
Loa Loa (eye worm) glutaminase 2 0.0306 0.5757 1
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0036 0.0575 0.0903
Plasmodium vivax hypothetical protein, conserved 0.0082 0.1468 0.1544
Brugia malayi MH2 domain containing protein 0.0131 0.2408 0.4183
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0009 0.0057 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0202 0.0331
Leishmania major glucose transporter, lmgt3 0.0036 0.0584 0.3925
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.119 0.1179
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0319 0.211
Trypanosoma cruzi DNA polymerase eta, putative 0.0007 0.002 0.0055
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0289 0.0502
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0009 0.0057 0.0268
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0584 0.3925
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0035 0.0561 0.2624
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0202 0.0331
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.119 0.205
Echinococcus multilocularis dna polymerase eta 0.0023 0.0319 0.1494
Leishmania major hypothetical protein, conserved 0.0016 0.0202 0.1304
Schistosoma mansoni coup transcription factor 0.0011 0.0102 0.0178
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0117 0.2137 1
Entamoeba histolytica protein kinase, putative 0.0036 0.0575 0.8597
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0082 0.1468 0.1458
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0102 0.0178
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Echinococcus multilocularis beta LACTamase domain containing family member 0.0082 0.1468 0.6871
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0667 0.114
Loa Loa (eye worm) MH1 domain-containing protein 0.0009 0.0057 0.0099
Trypanosoma brucei chrX additional, unordered contigs 0.0007 0.002 0.0055
Echinococcus granulosus TGF beta signal transducer SmadC 0.0009 0.0057 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0202 0.0331
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0102 0.0178
Leishmania major lysyl-tRNA synthetase, putative 0.0026 0.0388 0.2581
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0102 0.0178
Loa Loa (eye worm) hypothetical protein 0.0082 0.1468 0.2551
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0035 0.0561 0.0974
Entamoeba histolytica hypothetical protein 0.0026 0.0388 0.5742
Toxoplasma gondii transporter, major facilitator family protein 0.0016 0.0202 0.0305
Leishmania major glucose transporter, lmgt1 0.0036 0.0584 0.3925
Brugia malayi Smad1 0.0009 0.0057 0.0099
Echinococcus granulosus mothers against decapentaplegic 5 0.0009 0.0057 0.0268
Mycobacterium tuberculosis Conserved protein 0.0082 0.1468 0.1458
Plasmodium falciparum calcium-dependent protein kinase 2 0.0036 0.0575 0.0597
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0016 0.0202 0.0331
Trypanosoma cruzi glucose transporter, putative 0.0016 0.0202 0.1304
Schistosoma mansoni protein kinase 0.0036 0.0575 0.0999
Schistosoma mansoni DNA polymerase eta 0.0023 0.0319 0.0555
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Echinococcus granulosus Sugar transporter ERD6 protein 0.0016 0.0202 0.0945
Mycobacterium tuberculosis Probable hydrolase 0.0082 0.1468 0.1458
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Loa Loa (eye worm) beta-lactamase 0.0082 0.1468 0.2551
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0102 0.0178
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0036 0.0575 0.0597
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0036 0.0575 0.0903
Brugia malayi beta-lactamase family protein 0.0082 0.1468 0.2551
Echinococcus granulosus smad 0.0009 0.0057 0.0268
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0319 0.1494
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Mycobacterium tuberculosis Probable esterase LipL 0.0082 0.1468 0.1458
Brugia malayi nuclear hormone receptor 0.0011 0.0102 0.0178
Leishmania major glucose transporter, lmgt2 0.0036 0.0584 0.3925
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0102 0.0479
Schistosoma mansoni smad1 5 8 and 0.0009 0.0057 0.0099
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0082 0.1468 0.2535
Echinococcus multilocularis solute carrier family 22 0.0016 0.0202 0.0945
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0319 0.211
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0319 0.0555
Plasmodium falciparum calcium-dependent protein kinase 1 0.0036 0.0575 0.0597
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0584 0.3925
Toxoplasma gondii sugar transporter ST3 0.0016 0.0202 0.0305
Plasmodium vivax lysine--tRNA ligase, putative 0.0026 0.0388 0.0399
Brugia malayi Cam kinase protein 1 0.0036 0.0575 0.0999
Onchocerca volvulus 0.0082 0.1468 1
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0667 0.1158
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0319 0.0535
Trypanosoma brucei glucose transporter 1E 0.0036 0.0584 0.3925
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0036 0.0575 0.0597
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0102 0.0178
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0289 0.0278
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.1468 1
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0016 0.0202 0.019
Onchocerca volvulus 0.0082 0.1468 1
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.119 0.2066
Loa Loa (eye worm) hypothetical protein 0.0023 0.0319 0.0555
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0035 0.0561 0.2624
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Schistosoma mansoni ap endonuclease 0.0021 0.0289 0.0502
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.119 0.5566
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Toxoplasma gondii sugar transporter ST1 0.0016 0.0202 0.0305
Trypanosoma brucei glucose transporter, putative 0.0036 0.0584 0.3925
Schistosoma mansoni ap endonuclease 0.0021 0.0289 0.0502
Trypanosoma cruzi hypothetical protein, conserved 0.0007 0.002 0.0055
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0388 0.0674
Brugia malayi lysyl-tRNA synthetase 0.0026 0.0388 0.0674
Schistosoma mansoni protein kinase 0.0036 0.0575 0.0999
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0667 0.312
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Leishmania major DNA polymerase eta, putative 0.0023 0.0319 0.211
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0319 0.211
Giardia lamblia Sugar-proton symporter 0.0016 0.0202 0.2901
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Brugia malayi Sugar transporter family protein 0.0016 0.0202 0.0351
Toxoplasma gondii facilitative glucose transporter GT1 0.0117 0.2137 0.3408
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Trypanosoma brucei sugar transporter, putative 0.0016 0.0202 0.1304
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0041 0.0673 0.4537
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Plasmodium falciparum calcium-dependent protein kinase 3 0.0036 0.0575 0.0597
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0289 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Plasmodium falciparum hexose transporter 0.0117 0.2137 0.2253
Leishmania major DNA polymerase kappa, putative 0.0023 0.0319 0.211
Loa Loa (eye worm) hypothetical protein 0.0007 0.002 0.0035
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0584 0.0995
Mycobacterium tuberculosis Conserved protein 0.0082 0.1468 0.1458
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0007 0.0012 0.0021
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Onchocerca volvulus 0.0016 0.0202 0.0729
Brugia malayi MH2 domain containing protein 0.0009 0.0057 0.0099
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0388 0.0654
Onchocerca volvulus 0.0016 0.0202 0.0729
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0312 0.2061
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0102 0.0479
Giardia lamblia DINP protein human, muc B family 0.0023 0.0319 0.4694
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0575 0.269
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0102 0.0479
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0667 0.4495
Schistosoma mansoni smad1 5 8 and 0.0009 0.0057 0.0099
Toxoplasma gondii ABC1 family protein 0.0082 0.1468 0.2336
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.002 0.0055
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0319 0.4694
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0584 0.3925
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0036 0.0575 0.0597
Echinococcus granulosus dna polymerase eta 0.0023 0.0319 0.1494
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0319 0.211
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0667 1
Trypanosoma brucei glucose transporter, putative 0.0036 0.0584 0.3925
Toxoplasma gondii lysine-tRNA ligase 0.0026 0.0388 0.0603
Loa Loa (eye worm) hypothetical protein 0.0011 0.0102 0.0178
Loa Loa (eye worm) hypothetical protein 0.0011 0.0102 0.0178
Loa Loa (eye worm) hypothetical protein 0.0041 0.0667 0.1158
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0102 0.0178
Leishmania major myo-inositol/proton symporter (MIT) 0.0016 0.0202 0.1304
Onchocerca volvulus Putative transporter 0.0016 0.0202 0.0729
Brugia malayi beta-lactamase 0.0082 0.1468 0.2551
Onchocerca volvulus 0.0016 0.0202 0.0729
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0673 0.4537
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0319 0.211
Plasmodium vivax hexose transporter 0.0117 0.2137 0.2253
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0026 0.0388 0.2581
Trypanosoma brucei glucose transporter, putative 0.0036 0.0584 0.3925
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0102 0.0178
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0102 0.0178
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Echinococcus granulosus dna polymerase kappa 0.0023 0.0319 0.1494
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0289 0.0294
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.119 0.8085
Entamoeba histolytica protein kinase, putative 0.0036 0.0575 0.8597
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0102 0.0178
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0117 0.2137 1
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.019 0.3524 0.3724
Brugia malayi hypothetical protein 0.0016 0.0202 0.0351
Brugia malayi MH2 domain containing protein 0.0009 0.0057 0.0099
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0312 0.0301
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0319 0.211
Plasmodium falciparum lysine--tRNA ligase 0.0026 0.0388 0.0399
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0117 0.2137 1
Schistosoma mansoni sugar transporter 0.0016 0.0202 0.0351
Schistosoma mansoni glycyl-tRNA synthetase 0.0007 0.0012 0.0021
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0319 0.0535
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0102 0.0479
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Onchocerca volvulus 0.0016 0.0202 0.0729
Echinococcus multilocularis Smad4 0.0009 0.0057 0.0268
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0082 0.1468 0.2551
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0584 0.3925
Plasmodium falciparum protein kinase 6 0.0498 0.9443 1
Plasmodium vivax sugar transporter, putative 0.0016 0.0202 0.0201
Echinococcus multilocularis General substrate transporter 0.0101 0.1821 0.8518
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0102 0.0479
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0036 0.0575 0.0903
Leishmania major glucose transporter/membrane transporter D2, putative 0.0036 0.0584 0.3925
Plasmodium falciparum DNA repair protein REV1, putative 0.0007 0.002 0.0009
Trypanosoma brucei glucose transporter, putative 0.0036 0.0584 0.3925
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0102 0.0479
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0102 0.0178
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0102 0.0178
Giardia lamblia Hexose transporter 0.0016 0.0202 0.2901
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Trichomonas vaginalis glucose transporter, putative 0.0036 0.0584 0.0995
Schistosoma mansoni Smad4 0.0009 0.0057 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0102 0.0178
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0289 0.1904
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Echinococcus granulosus Smad4 0.0009 0.0057 0.0268
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0326 0.0547
Leishmania major DNA damage repair protein, putative 0.0007 0.002 0.0055
Plasmodium falciparum calcium-dependent protein kinase 5 0.0036 0.0575 0.0597
Trypanosoma brucei unspecified product 0.0016 0.0185 0.1185
Loa Loa (eye worm) hypothetical protein 0.0026 0.0388 0.0674
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0202 0.0351
Onchocerca volvulus 0.0016 0.0202 0.0729
Trypanosoma brucei glucose transporter, putative 0.0036 0.0584 0.3925
Trichomonas vaginalis D-aminoacylase, putative 0.0082 0.1468 0.2535
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0202 0.0351
Loa Loa (eye worm) sugar transporter 0.0117 0.2137 0.3712
Brugia malayi glycyl-tRNA synthetase 0.0007 0.0012 0.0021
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0102 0.0479
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Brugia malayi steroid hormone receptor 0.0011 0.0102 0.0178
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0102 0.0479
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0319 0.211
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Onchocerca volvulus 0.0016 0.0202 0.0729
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0102 0.0178
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0202 0.0351
Mycobacterium leprae Probable lipase LipE 0.0082 0.1468 1
Schistosoma mansoni glutaminase 0.0306 0.5757 1
Trypanosoma brucei hypothetical protein, conserved 0.0082 0.1468 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0667 0.312
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0289 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0016 0.0202 0.1304
Leishmania major hypothetical protein, conserved 0.0082 0.1468 1
Toxoplasma gondii sugar transporter ST2 0.0016 0.0202 0.0305
Schistosoma mansoni glucose transport protein 0.0117 0.2137 0.3712
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0667 0.312
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0319 0.0555
Leishmania major DNA polymerase kappa, putative 0.0007 0.002 0.0055
Trypanosoma brucei glucose transporter 2A 0.0036 0.0584 0.3925
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0102 0.0178
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0667 0.312
Echinococcus granulosus synaptic vesicle 2 protein 0.0016 0.0202 0.0945
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0575 0.269
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0102 0.0178
Echinococcus multilocularis solute carrier family 22 0.0016 0.0202 0.0945
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0667 0.114
Trichomonas vaginalis glutaminase, putative 0.0306 0.5757 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.019 0.3524 0.5632
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0036 0.0575 0.0999
Onchocerca volvulus 0.0016 0.0202 0.0729
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0012 0.0124 0.0195
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0289 0.0483
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0102 0.0479
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0102 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.0007 0.002 0.0055
Onchocerca volvulus 0.0016 0.0202 0.0729
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0667 0.312
Loa Loa (eye worm) hypothetical protein 0.0082 0.1468 0.2551
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0102 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0185 0.1185
Echinococcus granulosus solute carrier family 22 0.0016 0.0202 0.0945
Loa Loa (eye worm) hypothetical protein 0.0029 0.0434 0.0754
Brugia malayi hypothetical protein 0.0016 0.0202 0.0351
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0667 0.4495
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0289 0.1904
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0289 0.0294
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0319 0.1494
Mycobacterium ulcerans hypothetical protein 0.0007 0.002 0.0014
Brugia malayi major facilitator superfamily protein 0.0016 0.0202 0.0351
Brugia malayi hypothetical protein 0.0016 0.0202 0.0351
Plasmodium vivax calcium-dependent protein kinase, putative 0.0036 0.0575 0.0597
Loa Loa (eye worm) hypothetical protein 0.0082 0.1468 0.2551
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0319 0.211
Trypanosoma cruzi DNA damage repair protein, putative 0.0007 0.002 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0102 0.0178
Loa Loa (eye worm) hypothetical protein 0.0036 0.0575 0.0999
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0185 0.1185
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0575 0.0999
Loa Loa (eye worm) transcription factor SMAD2 0.0131 0.2408 0.4183
Chlamydia trachomatis lysine--tRNA ligase 0.0026 0.0388 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0007 0.002 0.0013
Echinococcus multilocularis calcium dependent protein kinase 0.0034 0.0532 0.249
Echinococcus granulosus glycyl tRNA synthetase 0.0007 0.0012 0.0056
Toxoplasma gondii exonuclease III APE 0.0021 0.0289 0.0445
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0319 0.211
Giardia lamblia DNA damage repair protein 0.0007 0.002 0.0123
Trichomonas vaginalis D-aminoacylase, putative 0.0082 0.1468 0.2535
Brugia malayi MH1 domain containing protein 0.0009 0.0057 0.0099
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0102 0.0479
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0289 0.1354
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0016 0.0202 0.019
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0102 0.0178
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0319 0.211
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0575 0.269
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0082 0.1468 0.1458
Brugia malayi ecdysteroid receptor 0.0011 0.0102 0.0178
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0319 0.211
Schistosoma mansoni protein kinase 0.0036 0.0575 0.0999
Onchocerca volvulus 0.0016 0.0202 0.0729
Brugia malayi nuclear receptor NHR-88 0.0011 0.0102 0.0178
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0289 0.1904
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0016 0.0202 0.0331
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0202 0.0351
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0102 0.0479
Plasmodium falciparum protein kinase 7 0.0331 0.6248 0.6612
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0102 0.0178
Schistosoma mansoni glucose transport protein 0.0117 0.2137 0.3712
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0041 0.0673 0.4537
Plasmodium vivax DNA repair protein REV1, putative 0.0007 0.002 0.0009
Echinococcus multilocularis solute carrier family 22 0.0016 0.0202 0.0945
Trypanosoma cruzi DNA damage repair protein, putative 0.0007 0.002 0.0055
Echinococcus multilocularis mothers against decapentaplegic 5 0.0009 0.0057 0.0268
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0388 0.0654
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0202 0.0331
Echinococcus multilocularis glycyl tRNA synthetase 0.0007 0.0012 0.0056
Loa Loa (eye worm) hypothetical protein 0.0011 0.0102 0.0178
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0289 0.4235
Loa Loa (eye worm) hypothetical protein 0.0011 0.0102 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.0007 0.002 0.0055
Brugia malayi major facilitator superfamily protein 0.0016 0.0202 0.0351
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0575 0.269
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.119 0.2066
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0667 0.1158
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0117 0.2137 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0185 0.1185
Treponema pallidum prolyl-tRNA synthetase 0.0012 0.0124 0.4037
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0319 0.211
Mycobacterium ulcerans beta-lactamase 0.0082 0.1468 0.2535
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0102 0.0178
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0289 0.1354
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0117 0.2137 1
Mycobacterium ulcerans integral membrane transport protein 0.0016 0.0202 0.0331
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Schistosoma mansoni DNA polymerase IV / kappa 0.0007 0.002 0.0035
Loa Loa (eye worm) hypothetical protein 0.0011 0.0102 0.0178
Onchocerca volvulus 0.0016 0.0202 0.0729
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0319 0.0555
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0584 0.3925
Onchocerca volvulus 0.0082 0.1468 1
Mycobacterium leprae conserved hypothetical protein 0.0082 0.1468 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0102 0.0178
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0667 0.4495
Onchocerca volvulus 0.0016 0.0202 0.0729
Onchocerca volvulus 0.0016 0.0202 0.0729
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0575 0.269
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0102 0.0178
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0007 0.0012 0.0021
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.002 0.0055
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0016 0.0202 0.0201
Echinococcus multilocularis solute carrier family 22 0.0016 0.0202 0.0945
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.0575 0.098
Plasmodium falciparum calcium-dependent protein kinase 4 0.0036 0.0575 0.0597
Loa Loa (eye worm) Smad1 0.0009 0.0057 0.0099
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0026 0.0388 0.2581
Loa Loa (eye worm) hypothetical protein 0.0082 0.1468 0.2551
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0102 0.0178
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0102 0.0479
Echinococcus granulosus solute carrier family 22 0.0016 0.0202 0.0945
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0026 0.0388 0.2581
Mycobacterium ulcerans esterase/lipase LipP 0.0082 0.1468 0.2535
Trypanosoma cruzi sugar transporter, putative 0.0016 0.0202 0.1304
Trichomonas vaginalis myo-inositol transporter, putative 0.0016 0.0202 0.0331
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0007 0.0012 0.0021
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0007 0.002 0.0013
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0102 0.0178
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0117 0.2137 1
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0007 0.0012 0.0021
Trypanosoma cruzi hexose transporter, putative 0.0016 0.0202 0.1304
Onchocerca volvulus 0.0016 0.0202 0.0729
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0575 0.269
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0202 0.0331
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0016 0.0202 0.0351
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Loa Loa (eye worm) hypothetical protein 0.0082 0.1468 0.2551
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.119 0.205
Trichomonas vaginalis glucose transporter, putative 0.0036 0.0584 0.0995
Echinococcus multilocularis synaptic vesicle 2 protein 0.0016 0.0202 0.0945
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0036 0.0575 0.3865
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0035 0.0561 0.0974
Loa Loa (eye worm) glutaminase 0.0306 0.5757 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0102 0.0178
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0117 0.2137 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0102 0.0178
Trypanosoma brucei glucose transporter, putative 0.0036 0.0584 0.3925
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0082 0.1468 0.2551
Brugia malayi polk-prov protein 0.0007 0.002 0.0035
Onchocerca volvulus 0.0016 0.0202 0.0729
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0007 0.0012 0.0056
Trypanosoma brucei unspecified product 0.0016 0.0185 0.1185
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.119 0.1888
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Schistosoma mansoni sugar transporter 0.0016 0.0202 0.0351
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0319 0.1494
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0016 0.0202 0.0945
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0082 0.1468 0.1458
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0319 0.211
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0351
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0289 0.0483
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0041 0.0673 0.106
Trichomonas vaginalis esterase, putative 0.0082 0.1468 0.2535
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0202 0.0331
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0082 0.1468 0.2551
Echinococcus granulosus calcium dependent protein kinase 0.0034 0.0532 0.249

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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