TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 342.336 | Formula: C15H13F3N2O2S
H donors: 1 H acceptors: 3 LogP: 2.81 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: OC1CCN(C1)C(=O)c1csc(n1)c1cccc(c1)C(F)(F)F
InChi: 1S/C15H13F3N2O2S/c16-15(17,18)10-3-1-2-9(6-10)13-19-12(8-23-13)14(22)20-5-4-11(21)7-20/h1-3,6,8,11,21H,4-5,7H2
InChiKey: JBJRQIOZJMQMCD-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma brucei	unspecified product	0.0022	0.0011	0.0015
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0035	0.0028	0.0021
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Echinococcus multilocularis	uncharacterized sodium dependent transporter	0.0042	0.0037	0.0029
Echinococcus multilocularis	fmrfamide receptor	0.0035	0.0028	0.0021
Brugia malayi	Sodium:neurotransmitter symporter family protein 1, putative	0.0042	0.0037	0.0035
Brugia malayi	Thioredoxin reductase	0.0055	0.0053	0.0052
Loa Loa (eye worm)	vesicular acetylcholine transporter unc-17	0.789	1	1
Onchocerca volvulus		0.0035	0.0028	0.0001
Trichomonas vaginalis	DNA helicase recq1, putative	0.0024	0.0014	0.0433
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0035	0.0028	0.0021
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	somatostatin receptor	0.0035	0.0028	0.0021
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Trichomonas vaginalis	ap endonuclease, putative	0.0021	0.0011	0.0322
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Echinococcus multilocularis	neuropeptide Y receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	tm gpcr rhodopsin	0.0035	0.0028	0.0021
Plasmodium falciparum	transporter, putative	0.0042	0.0037	0.6352
Onchocerca volvulus		0.0035	0.0028	0.0001
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0035	0.0028	0.0021
Echinococcus multilocularis	allatostatin A receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	myosin xvIII	0.0035	0.0028	0.0021
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0021	0.0011	0.0107
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Leishmania major	DNA polymerase eta, putative	0.0022	0.0011	0.0015
Echinococcus multilocularis	G protein coupled receptor 139	0.0035	0.0028	0.0021
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0035	0.0028	0.0001
Loa Loa (eye worm)	solute carrier family 6 member 4	0.0247	0.0297	0.0289
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0035	0.0028	0.0027
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.0021	0.0011	0.8119
Onchocerca volvulus		0.0035	0.0028	0.0001
Onchocerca volvulus		0.0035	0.0028	0.0001
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.0022	0.0011	0.0003
Onchocerca volvulus		0.0035	0.0028	0.0001
Brugia malayi	hypothetical protein	0.0035	0.0028	0.0027
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	biogenic amine 5HT receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Brugia malayi	Pre-SET motif family protein	0.0035	0.0028	0.0026
Onchocerca volvulus		0.0035	0.0028	0.0001
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0035	0.0028	0.0021
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0035	0.0028	0.0021
Echinococcus granulosus	thioredoxin glutathione reductase	0.0055	0.0053	0.0046
Loa Loa (eye worm)	thioredoxin reductase	0.0055	0.0053	0.0045
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Brugia malayi	hypothetical protein	0.0035	0.0028	0.0027
Echinococcus granulosus	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0037	0.0029
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Echinococcus multilocularis	geminin	0.0391	0.048	0.0472
Loa Loa (eye worm)	serotonin transporter b	0.0247	0.0297	0.0289
Loa Loa (eye worm)	neuropeptide F receptor	0.0035	0.0028	0.002
Trypanosoma brucei	dihydrolipoyl dehydrogenase	0.0019	0.0008	0.001
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0035	0.0028	0.0021
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.0042	0.0037	0.0029
Echinococcus granulosus	7TM GPCR rhodopsin	0.0035	0.0028	0.0021
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0019	0.0008	0.001
Onchocerca volvulus		0.0276	0.0333	0.0307
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0035	0.0028	0.0021
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0022	0.0011	0.0248
Trichomonas vaginalis	DNA polymerase eta, putative	0.0022	0.0011	0.0344
Schistosoma mansoni	amine GPCR	0.0035	0.0028	0.0021
Brugia malayi	putative neuropeptide receptor	0.0035	0.0028	0.0027
Schistosoma mansoni	vesicular amine transporter	0.0192	0.0228	0.022
Leishmania major	2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein	0.0019	0.0008	0.001
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0021	0.0011	0.8119
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0037	0.0029
Brugia malayi	Melatonin receptor type 1A	0.0035	0.0028	0.0027
Trypanosoma brucei	C-8 sterol isomerase, putative	0.5908	0.7484	1
Toxoplasma gondii	hypothetical protein	0.0042	0.0037	0.6613
Schistosoma mansoni	ap endonuclease	0.0021	0.0011	0.0003
Treponema pallidum	sodium- and chloride- dependent transporter	0.0247	0.0297	1
Leishmania major	C-14 sterol reductase, putative	0.0098	0.0108	0.0145
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0035	0.0028	0.0021
Echinococcus multilocularis	survival motor neuron protein 1	0.027	0.0327	0.0319
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Echinococcus multilocularis	g protein coupled receptor	0.0035	0.0028	0.0021
Echinococcus multilocularis	serotonin transporter	0.0247	0.0297	0.0289
Plasmodium vivax	SET domain protein, putative	0.0035	0.0028	0.4735
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0035	0.0028	0.0021
Echinococcus granulosus	g protein coupled receptor	0.0035	0.0028	0.0021
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0035	0.0028	0.0021
Trypanosoma cruzi	C-8 sterol isomerase, putative	0.5908	0.7484	1
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0021	0.0011	0.0003
Trichomonas vaginalis	DNA helicase recq, putative	0.0024	0.0014	0.0433
Onchocerca volvulus		0.0035	0.0028	0.0001
Onchocerca volvulus		0.0035	0.0028	0.0001
Loa Loa (eye worm)	hypothetical protein	0.5908	0.7484	0.7481
Echinococcus granulosus	fmrfamide receptor	0.0035	0.0028	0.0021
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0035	0.0028	0.002
Leishmania major	acetoin dehydrogenase e3 component-like protein	0.0019	0.0008	0.001
Echinococcus granulosus	serotonin transporter	0.0247	0.0297	0.0289
Brugia malayi	RE15519p	0.0035	0.0028	0.0027
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0035	0.0028	0.0021
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0126	0.0143	0.8837
Loa Loa (eye worm)	hypothetical protein	0.3019	0.3817	0.3812
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0035	0.0028	0.0021
Echinococcus multilocularis	lamin b receptor	0.0098	0.0108	0.0101
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0126	0.0143	0.8837
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0035	0.0028	0.002
Brugia malayi	G-protein coupled receptor	0.0035	0.0028	0.0027
Schistosoma mansoni	biogenic amine receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0035	0.0028	0.0021
Echinococcus multilocularis	bloom syndrome protein	0.0024	0.0014	0.0007
Loa Loa (eye worm)	RecQ helicase	0.0024	0.0014	0.0006
Loa Loa (eye worm)	glutathione reductase	0.0055	0.0053	0.0045
Trichomonas vaginalis	set domain proteins, putative	0.0276	0.0333	1
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.0042	0.0037	0.0029
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Trypanosoma cruzi	dihydrolipoyl dehydrogenase, putative	0.0019	0.0008	0.001
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0021	0.0011	0.0003
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0035	0.0028	0.002
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0035	0.0028	0.0021
Trypanosoma brucei	unspecified product	0.0015	0.0003	0.0004
Trypanosoma brucei	DNA polymerase IV, putative	0.0022	0.0011	0.0015
Echinococcus granulosus	dro:myosuppressin receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	neuropeptide Y receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	neuropeptide receptor A26	0.0035	0.0028	0.0021
Echinococcus granulosus	sodium and chloride dependent glycine	0.0042	0.0037	0.0029
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Brugia malayi	Dopamine receptor protein 2	0.0035	0.0028	0.0027
Loa Loa (eye worm)	norepinephrine transporter	0.0247	0.0297	0.0289
Toxoplasma gondii	Sodium:neurotransmitter symporter family protein	0.0042	0.0037	0.6613
Echinococcus granulosus	geminin	0.0391	0.048	0.0472
Onchocerca volvulus		0.0035	0.0028	0.0001
Leishmania major	C-8 sterol isomerase-like protein	0.5908	0.7484	1
Echinococcus granulosus	G protein coupled receptor 139	0.0035	0.0028	0.0021
Brugia malayi	glutathione reductase	0.0055	0.0053	0.0052
Echinococcus granulosus	hypothetical protein	0.0035	0.0028	0.0021
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0035	0.0028	0.0021
Brugia malayi	Serotonin receptor	0.0035	0.0028	0.0027
Echinococcus granulosus	g protein coupled receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	sodium-dependent neurotransmitter transporter	0.0042	0.0037	0.0029
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0035	0.0028	0.0021
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0019	0.0008	0.001
Plasmodium falciparum	thioredoxin reductase	0.0055	0.0053	1
Echinococcus multilocularis	neuropeptide Y receptor	0.0035	0.0028	0.0021
Echinococcus multilocularis	sodium:chloride dependent neurotransmitter	0.0042	0.0037	0.0029
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0035	0.0028	0.0021
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0035	0.0028	0.002
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0021	0.0011	0.0014
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0035	0.0028	0.0001
Echinococcus granulosus	tm gpcr rhodopsin	0.1145	0.1437	0.1431
Brugia malayi	Abnormal catecholamine distribution protein 1	0.0192	0.0228	0.0226
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.0042	0.0037	0.0029
Leishmania major	dihydrolipoamide dehydrogenase, putative	0.0019	0.0008	0.001
Schistosoma mansoni	hypothetical protein	0.0035	0.0028	0.0021
Schistosoma mansoni	sodium/chloride dependent transporter	0.0042	0.0037	0.0029
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.0022	0.0011	0.0004
Echinococcus granulosus	dna polymerase eta	0.0022	0.0011	0.0004
Echinococcus multilocularis	vesicular acetylcholine transporter	0.789	1	1
Onchocerca volvulus		0.0035	0.0028	0.0001
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0021	0.0011	0.0675
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Mycobacterium tuberculosis	Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed))	0.0022	0.0011	0.0248
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.0055	0.0053	0.2985
Echinococcus granulosus	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0247	0.0297	0.0296
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0035	0.0028	0.0027
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Trypanosoma cruzi	C-14 sterol reductase, putative	0.0098	0.0108	0.0145
Schistosoma mansoni	amine GPCR	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.014	0.0161	1
Echinococcus multilocularis	dna polymerase eta	0.0022	0.0011	0.0004
Schistosoma mansoni	amine GPCR	0.0035	0.0028	0.0021
Echinococcus granulosus	g protein coupled receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	uncharacterized sodium dependent transporter	0.0042	0.0037	0.0029
Echinococcus multilocularis	fmrfamide receptor	0.0035	0.0028	0.0021
Echinococcus multilocularis	sodium dependent neurotransmitter transporter	0.0042	0.0037	0.0029
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.0022	0.0011	0.0004
Schistosoma mansoni	neuropeptide receptor	0.0035	0.0028	0.0021
Brugia malayi	AKH receptor	0.0035	0.0028	0.0027
Brugia malayi	ImpB/MucB/SamB family protein	0.0022	0.0011	0.001
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0033	0.0026	0.0018
Brugia malayi	dihydrolipoyl dehydrogenase, mitochondrial precursor, putative	0.0019	0.0008	0.0006
Trypanosoma brucei	dihydrolipoamide dehydrogenase	0.0019	0.0008	0.001
Schistosoma mansoni	sodium-dependent neurotransmitter transporter	0.0042	0.0037	0.0029
Schistosoma mansoni	hypothetical protein	0.0035	0.0028	0.0021
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Plasmodium vivax	amine transporter, putative	0.0042	0.0037	0.6596
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.0021	0.0011	0.0201
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Brugia malayi	Serotonin receptor	0.0035	0.0028	0.0027
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0035	0.0028	0.0021
Leishmania major	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Echinococcus granulosus	sodium dependent neurotransmitter transporter	0.0042	0.0037	0.0029
Schistosoma mansoni	neuropeptide receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	histamine h1 receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0035	0.0028	0.0021
Trypanosoma brucei	DNA polymerase IV, putative	0.0022	0.0011	0.0015
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0037	0.0029
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Trichomonas vaginalis	mercuric reductase, putative	0.0019	0.0008	0.023
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Schistosoma mansoni	sodium-dependent neurotransmitter transporter	0.0042	0.0037	0.0029
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Echinococcus multilocularis	g-protein coupled receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	histone lysine methyltransferase setb	0.0035	0.0028	0.002
Echinococcus granulosus	neuropeptide s receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0035	0.0028	0.002
Brugia malayi	ERG2 and Sigma1 receptor like protein	0.5908	0.7484	0.7483
Echinococcus multilocularis	sodium and chloride dependent glycine	0.0042	0.0037	0.0029
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Echinococcus granulosus	g-protein coupled receptor	0.0035	0.0028	0.0021
Toxoplasma gondii	NADPH-glutathione reductase	0.0019	0.0008	0.0716
Onchocerca volvulus		0.0035	0.0028	0.0001
Echinococcus multilocularis	serotonin receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.0247	0.0297	0.0289
Brugia malayi	GnHR receptor homolog	0.0035	0.0028	0.0027
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0035	0.0028	0.0021
Echinococcus granulosus	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0021	0.0011	0.0014
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0126	0.0143	0.8837
Echinococcus granulosus	neuropeptide receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	DNA polymerase eta	0.0022	0.0011	0.0004
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0126	0.0143	0.8837
Echinococcus multilocularis	neuropeptides capa receptor	0.0035	0.0028	0.0021
Onchocerca volvulus		0.0035	0.0028	0.0001
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Brugia malayi	exodeoxyribonuclease III family protein	0.0021	0.0011	0.001
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Trypanosoma cruzi	trypanothione reductase, putative	0.0055	0.0053	0.0071
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.0019
Trypanosoma cruzi	sterol C-24 reductase, putative	0.0051	0.0048	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0035	0.0028	0.002
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0019	0.0008	0.001
Mycobacterium ulcerans	DNA polymerase IV	0.0022	0.0011	1
Brugia malayi	neuropeptide F receptor	0.0035	0.0028	0.0027
Onchocerca volvulus		0.0247	0.0297	0.027
Echinococcus granulosus	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Echinococcus granulosus	7tm_1 domain containing protein	0.0035	0.0028	0.0021
Brugia malayi	putative neuropeptide receptor NPR1	0.0035	0.0028	0.0027
Plasmodium vivax	dihydrolipoyl dehydrogenase, apicoplast, putative	0.0019	0.0008	0.0669
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Trypanosoma cruzi	DNA polymerase eta, putative	0.0022	0.0011	0.0015
Loa Loa (eye worm)	hypothetical protein	0.0247	0.0297	0.0289
Onchocerca volvulus	Vesicular acetylcholine transporter homolog	0.789	1	1
Echinococcus granulosus	allatostatin A receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Brugia malayi	neuropeptide F receptor	0.0035	0.0028	0.0027
Echinococcus multilocularis	somatostatin receptor	0.0035	0.0028	0.0021
Toxoplasma gondii	exonuclease III APE	0.0021	0.0011	0.1343
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.0022	0.0011	0.0004
Trypanosoma brucei	DNA polymerase kappa, putative	0.0015	0.0003	0.0004
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Mycobacterium tuberculosis	Probable oxidoreductase	0.014	0.0161	1
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Echinococcus granulosus	sodium:chloride dependent neurotransmitter	0.0042	0.0037	0.0029
Echinococcus granulosus	bloom syndrome protein	0.0024	0.0014	0.0007
Schistosoma mansoni	sodium/chloride dependent transporter	0.0042	0.0037	0.0029
Loa Loa (eye worm)	hypothetical protein	0.0247	0.0297	0.0289
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0035	0.0028	0.0027
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.0022	0.0011	0.0015
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	neuropeptide F-like receptor	0.0035	0.0028	0.0021
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0042	0.0037	0.0035
Brugia malayi	larval opioid receptor	0.0035	0.0028	0.0027
Echinococcus granulosus	orexin receptor type 2	0.0035	0.0028	0.0021
Trypanosoma brucei	dihydrolipoamide dehydrogenase	0.0019	0.0008	0.001
Trypanosoma brucei	DNA polymerase kappa, putative	0.0015	0.0003	0.0004
Schistosoma mansoni	survival motor neuron protein	0.0055	0.0053	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0247	0.0297	0.0289
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0035	0.0028	0.0027
Echinococcus granulosus	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Schistosoma mansoni	neuropeptide F-like receptor	0.0035	0.0028	0.0021
Onchocerca volvulus		0.0055	0.0053	0.0026
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Trypanosoma brucei	dihydrolipoamide dehydrogenase, point mutation	0.0019	0.0008	0.001
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0035	0.0028	0.0021
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0021	0.0011	0.0014
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Onchocerca volvulus		0.0035	0.0028	0.0001
Schistosoma mansoni	hypothetical protein	0.0391	0.048	0.0472
Onchocerca volvulus		0.0042	0.0037	0.0009
Schistosoma mansoni	adenoreceptor	0.0035	0.0028	0.0021
Brugia malayi	hypothetical protein	0.0035	0.0028	0.0027
Echinococcus multilocularis	g protein coupled receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Echinococcus granulosus	sex peptide receptor	0.0035	0.0028	0.0021
Brugia malayi	hypothetical protein	0.0035	0.0028	0.0027
Plasmodium vivax	dihydrolipoyl dehydrogenase, mitochondrial, putative	0.0019	0.0008	0.0669
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0021	0.0011	0.1299
Trypanosoma brucei	C-14 sterol reductase, putative	0.0098	0.0108	0.0145
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0035	0.0028	0.002
Toxoplasma gondii	Sodium:neurotransmitter symporter family protein	0.0042	0.0037	0.6613
Loa Loa (eye worm)	hypothetical protein	0.027	0.0327	0.0319
Brugia malayi	hypothetical protein	0.0035	0.0028	0.0027
Schistosoma mansoni	hypothetical protein	0.0035	0.0028	0.0021
Echinococcus multilocularis	neuropeptide receptor A26	0.0035	0.0028	0.0021
Leishmania major	dihydrolipoamide dehydrogenase, putative	0.0019	0.0008	0.001
Loa Loa (eye worm)	melatonin receptor type 1A	0.0035	0.0028	0.002
Onchocerca volvulus		0.0042	0.0037	0.0009
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.1145	0.1437	0.1431
Brugia malayi	Pre-SET motif family protein	0.0242	0.0291	0.029
Loa Loa (eye worm)	Sodium:neurotransmitter symporter family protein	0.0042	0.0037	0.0029
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0035	0.0028	0.0021
Echinococcus granulosus	dna polymerase kappa	0.0022	0.0011	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0242	0.0291	0.0283
Brugia malayi	G-protein coupled receptor	0.0035	0.0028	0.0027
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0035	0.0028	0.002
Schistosoma mansoni	Lamin B receptor (ERG24)	0.0098	0.0108	0.0101
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0035	0.0028	0.0027
Echinococcus multilocularis	synaptic vesicular amine transporter	0.0192	0.0228	0.022
Echinococcus multilocularis	dro:myosuppressin receptor	0.0035	0.0028	0.0021
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Trichomonas vaginalis	glutathione reductase, putative	0.0019	0.0008	0.023
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0019	0.0008	0.001
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0035	0.0028	0.0021
Echinococcus granulosus	neuropeptides capa receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0298	0.0362	0.0354
Onchocerca volvulus		0.0035	0.0028	0.0001
Schistosoma mansoni	hypothetical protein	0.0391	0.048	0.0472
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0035	0.0028	0.0021
Loa Loa (eye worm)	Sodium:neurotransmitter symporter family protein	0.0042	0.0037	0.0029
Brugia malayi	ORL1-like opioid receptor	0.0035	0.0028	0.0027
Trypanosoma brucei	DNA polymerase IV, putative	0.0022	0.0011	0.0015
Echinococcus granulosus	neuropeptides capa receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	biogenic amine 5HT receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	tm gpcr rhodopsin	0.0035	0.0028	0.0021
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0055	0.0053	0.0046
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Brugia malayi	Dopamine receptor	0.0035	0.0028	0.0027
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0035	0.0028	0.0021
Schistosoma mansoni	biogenic amine receptor	0.0035	0.0028	0.0021
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0021	0.0011	0.0014
Brugia malayi	G protein-coupled receptor	0.0035	0.0028	0.0027
Mycobacterium tuberculosis	Probable reductase	0.0126	0.0143	0.8837
Echinococcus multilocularis	serotonin receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.0042	0.0037	0.0029
Brugia malayi	sulfakinin receptor protein	0.0035	0.0028	0.0027
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0011	0.0003
Trypanosoma cruzi	trypanothione reductase, putative	0.0019	0.0008	0.001
Schistosoma mansoni	growth hormone secretagogue receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0051	0.0048	0.004
Mycobacterium tuberculosis	Probable dehydrogenase	0.0126	0.0143	0.8837
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0021	0.0011	0.0003
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0037	0.0029
Onchocerca volvulus		0.0035	0.0028	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Schistosoma mansoni	opsin-like receptor	0.0035	0.0028	0.0021
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0035	0.0028	0.0021
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0042	0.0037	0.0035
Schistosoma mansoni	ap endonuclease	0.0021	0.0011	0.0003
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0042	0.0037	0.0035
Mycobacterium ulcerans	DNA polymerase IV	0.0022	0.0011	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Echinococcus multilocularis	orexin receptor type 2	0.0035	0.0028	0.0021
Echinococcus granulosus	lamin b receptor	0.0098	0.0108	0.0101
Trypanosoma brucei	DNA polymerase kappa, putative	0.0015	0.0003	0.0004
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	neuropeptide FF receptor 2	0.0035	0.0028	0.0021
Brugia malayi	G protein-coupled receptor F59B2.13	0.0035	0.0028	0.0027
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0055	0.0053	0.0052
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Toxoplasma gondii	hypothetical protein	0.0042	0.0037	0.6613
Loa Loa (eye worm)	G-protein coupled receptor	0.0035	0.0028	0.002
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	hypothetical protein	0.0035	0.0028	0.0021
Trypanosoma brucei	trypanothione reductase	0.0055	0.0053	0.0071
Schistosoma mansoni	neuropeptide receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	neuropeptide f receptor 76f	0.0035	0.0028	0.0021
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0021	0.0011	1
Trypanosoma cruzi	sterol C-24 reductase, putative	0.0051	0.0048	0.0065
Trypanosoma cruzi	dihydrolipoyl dehydrogenase, putative	0.0019	0.0008	0.001
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0035	0.0028	0.0021
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Echinococcus granulosus	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Onchocerca volvulus		0.0035	0.0028	0.0001
Echinococcus granulosus	sodium and chloride dependent glycine	0.0042	0.0037	0.0029
Brugia malayi	hypothetical protein	0.0035	0.0028	0.0027
Echinococcus granulosus	uncharacterized sodium dependent transporter	0.0042	0.0037	0.0029
Loa Loa (eye worm)	TYRA-2 protein	0.0035	0.0028	0.002
Schistosoma mansoni	biogenic amine receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	neuropeptide receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0035	0.0028	0.4762
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0035	0.0028	0.0021
Trichomonas vaginalis	ap endonuclease, putative	0.0021	0.0011	0.0322
Echinococcus granulosus	vesicular acetylcholine transporter	0.789	1	1
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.0021	0.0011	0.9377
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0019	0.0008	0.001
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Echinococcus granulosus	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Echinococcus multilocularis	neuropeptides capa receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0035	0.0028	0.0021
Schistosoma mansoni	neuropeptide receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.014	0.0161	1
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Plasmodium vivax	glutathione reductase, putative	0.0055	0.0053	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Echinococcus multilocularis	neuropeptide receptor	0.0035	0.0028	0.0021
Trypanosoma cruzi	dihydrolipoamide dehydrogenase, putative	0.0019	0.0008	0.001
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Schistosoma mansoni	vesicular acetylcholine transporter	0.789	1	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Onchocerca volvulus		0.0035	0.0028	0.0001
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Brugia malayi	Bloom's syndrome protein homolog	0.0024	0.0014	0.0013
Trypanosoma brucei	DNA polymerase eta, putative	0.0022	0.0011	0.0015
Echinococcus granulosus	survival motor neuron protein 1	0.027	0.0327	0.0319
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Entamoeba histolytica	deoxycytidyl transferase, putative	0.0022	0.0011	1
Toxoplasma gondii	Sodium:neurotransmitter symporter family protein	0.0042	0.0037	0.6613
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0022	0.0011	0.0015
Brugia malayi	hypothetical protein	0.0035	0.0028	0.0027
Brugia malayi	hypothetical protein	0.027	0.0327	0.0325
Loa Loa (eye worm)	abnormal catecholamine distribution protein 1	0.0192	0.0228	0.022
Echinococcus multilocularis	neuropeptide receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	opsin-like receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	G-protein coupled receptor	0.0035	0.0028	0.002
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0035	0.0028	0.0027
Brugia malayi	follicle stimulating hormone receptor	0.0298	0.0362	0.0361
Echinococcus multilocularis	neuropeptide s receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.0042	0.0037	0.0029
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0035	0.0028	0.002
Schistosoma mansoni	hypothetical protein	0.0055	0.0053	0.0046
Brugia malayi	Dopamine receptor protein 1	0.0035	0.0028	0.0027
Brugia malayi	hypothetical protein	0.0042	0.0037	0.0035
Toxoplasma gondii	pyruvate dehydrogenase complex subunit PDH-E3II	0.0019	0.0008	0.0716
Leishmania major	trypanothione reductase	0.0055	0.0053	0.0071
Plasmodium falciparum	glutathione reductase	0.0055	0.0053	1
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Brugia malayi	ImpB/MucB/SamB family protein	0.0022	0.0011	0.001
Echinococcus multilocularis	dna polymerase kappa	0.0022	0.0011	0.0004
Brugia malayi	hypothetical protein	0.0035	0.0028	0.0027
Chlamydia trachomatis	Ssodium-dependent amino acid transporter	0.0042	0.0037	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0035	0.0028	0.0021
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0022	0.0011	0.0344
Echinococcus multilocularis	g protein coupled receptor	0.0035	0.0028	0.0021
Schistosoma mansoni	amine GPCR	0.0035	0.0028	0.0021
Trypanosoma cruzi	C-14 sterol reductase, putative	0.0098	0.0108	0.0145
Schistosoma mansoni	opsin-like receptor	0.0035	0.0028	0.0021
Echinococcus multilocularis	sex peptide receptor	0.0035	0.0028	0.0021
Plasmodium falciparum	amino acid transporter, putative	0.0042	0.0037	0.6352
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.014	0.0161	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0037	0.0029
Onchocerca volvulus		0.0042	0.0037	0.0009
Schistosoma mansoni	sodium/chloride dependent transporter	0.0247	0.0297	0.0289
Echinococcus granulosus	neuropeptide Y receptor	0.0035	0.0028	0.0021
Brugia malayi	hypothetical protein	0.0035	0.0028	0.0027
Schistosoma mansoni	terminal deoxycytidyl transferase	0.0022	0.0011	0.0004
Plasmodium vivax	thioredoxin reductase, putative	0.0055	0.0053	1
Schistosoma mansoni	amine GPCR	0.0035	0.0028	0.0021
Plasmodium vivax	hypothetical protein, conserved	0.0042	0.0037	0.6596
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0028	0.002
Echinococcus granulosus	serotonin receptor	0.0035	0.0028	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0037	0.0029
Leishmania major	sterol C-24 reductase, putative	0.0051	0.0048	0.0065
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0035	0.0028	0.002
Brugia malayi	hypothetical protein	0.0035	0.0028	0.0027
Schistosoma mansoni	sodium-dependent amino acid transporter	0.0042	0.0037	0.0029
Toxoplasma gondii	thioredoxin reductase	0.0055	0.0053	1
Plasmodium falciparum	ADP-dependent DNA helicase RecQ	0.0021	0.0011	0.0656
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0037	0.0029
Giardia lamblia	DINP protein human, muc B family	0.0022	0.0011	1
Echinococcus granulosus	synaptic vesicular amine transporter	0.0192	0.0228	0.022
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0035	0.0028	0.0021
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0035	0.0028	0.0021
Trypanosoma brucei	unspecified product	0.0015	0.0003	0.0004
Loa Loa (eye worm)	neuropeptide F receptor	0.0035	0.0028	0.002
Echinococcus multilocularis	sodium and chloride dependent glycine	0.0042	0.0037	0.0029

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 889516