Detailed information for compound 915249

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 455.5 | Formula: C25H29NO7
  • H donors: 2 H acceptors: 5 LogP: 1.95 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C(Oc1cccc2c1cccc2)C)OC1CC2CCC(C1)N2C.OC(=O)/C=C\C(=O)O
  • InChi: 1S/C21H25NO3.C4H4O4/c1-14(24-20-9-5-7-15-6-3-4-8-19(15)20)21(23)25-18-12-16-10-11-17(13-18)22(16)2;5-3(6)1-2-4(7)8/h3-9,14,16-18H,10-13H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
  • InChiKey: GGELOCHEHMWLGH-BTJKTKAUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis cyclins, putative 0.0292 0.0854 0.2273
Entamoeba histolytica cysteine protease, putative 0.0218 0.0611 0.1626
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0359 0.0955
Giardia lamblia Cathepsin L precursor 0.0218 0.0611 0.7153
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0051 0.0069
Schistosoma mansoni cyclin G2 0.004 0.0031 0.0052
Trichomonas vaginalis cyclins, putative 0.004 0.0031 0.008
Onchocerca volvulus 0.1179 0.3754 0.9469
Schistosoma mansoni cathepsin s 0.039 0.1174 0.2024
Trichomonas vaginalis cyclin B, putative 0.004 0.0031 0.008
Brugia malayi Tyrosine-protein kinase abl-1 0.0094 0.0206 0.0206
Brugia malayi excitatory GABA receptor EXP-1A 0.0582 0.1801 0.1801
Echinococcus multilocularis transient receptor potential ion channel A 0.0095 0.0211 0.0286
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0297 0.0871 0.2318
Plasmodium vivax serine-repeat antigen (SERA) 0.0218 0.0611 0.1626
Echinococcus multilocularis dual specificity protein kinase clk2 0.0071 0.0133 0.018
Plasmodium vivax cyclin homologue, putative 0.004 0.0031 0.008
Echinococcus multilocularis nAChR subunit 0.0582 0.1801 0.2449
Leishmania major cathepsin L-like protease 0.1179 0.3754 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.0031 0.0031
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0048 0.0057 0.0151
Entamoeba histolytica cyclin, putative 0.0292 0.0854 0.2273
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0071 0.0133 0.0353
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1179 0.3754 1
Loa Loa (eye worm) hypothetical protein 0.0218 0.0611 0.061
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0031 0.0001 0.0001
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0218 0.0611 0.7153
Echinococcus multilocularis twik family of potassium channels 0.0031 0.0001 0.0000073788
Brugia malayi Cathepsin L-like cysteine proteinase 0.0789 0.248 0.248
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0313 0.0924 0.0924
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Echinococcus multilocularis cyclin k 0.004 0.0031 0.0041
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0607 0.1885 0.5021
Onchocerca volvulus 0.1026 0.3252 0.8201
Trichomonas vaginalis cyclins, putative 0.004 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0218 0.0611 0.061
Echinococcus multilocularis small conductance calcium activated potassium 0.0859 0.2709 0.3685
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0027 0.0036
Trypanosoma cruzi cruzipain precursor, putative 0.1179 0.3754 1
Brugia malayi Papain family cysteine protease containing protein 0.0607 0.1885 0.1885
Schistosoma mansoni nAChR subunit 0.0582 0.1801 0.3106
Echinococcus multilocularis cyclins 0.0166 0.0442 0.0601
Schistosoma mansoni nAChR subunit 0.0582 0.1801 0.3106
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.0386 0.0386
Echinococcus multilocularis geminin 0.0184 0.0502 0.0682
Brugia malayi cell division control protein 2 homolog 0.0048 0.0057 0.0057
Schistosoma mansoni transient receptor potential channel 0.0098 0.0222 0.0381
Onchocerca volvulus 0.0268 0.0777 0.1957
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0031 0.008
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1179 0.3754 0.5107
Giardia lamblia Cathepsin B precursor 0.0218 0.0611 0.7153
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0582 0.1801 0.2449
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0798 0.2507 0.341
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0048 0.0057 0.0057
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0359 0.0955
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0582 0.1801 0.1801
Loa Loa (eye worm) ACC-1 protein 0.0582 0.1801 0.18
Leishmania major protein kinase, putative 0.0071 0.0133 0.0353
Brugia malayi Cathepsin L-like precursor 0.0789 0.248 0.248
Toxoplasma gondii thioredoxin reductase 0.0052 0.007 0.0185
Giardia lamblia Cathepsin B precursor 0.0218 0.0611 0.7153
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0582 0.1801 0.18
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0071 0.0133 0.0353
Loa Loa (eye worm) hypothetical protein 0.0046 0.0051 0.005
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0046 0.0051 0.0087
Giardia lamblia Cysteine protease 0.0218 0.0611 0.7153
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0582 0.1801 0.1801
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0218 0.0611 0.1626
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Loa Loa (eye worm) fibroinase 0.1179 0.3754 0.3754
Loa Loa (eye worm) hypothetical protein 0.0218 0.0611 0.061
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Leishmania major protein kinase, putative 0.0071 0.0133 0.0353
Giardia lamblia Tenascin-like 0.0063 0.0106 0.123
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Schistosoma mansoni twik family of potassium channels-related 0.0031 0.0001 0.0000093566
Echinococcus granulosus potassium channel subfamily K 0.0031 0.0001 0.0000073788
Echinococcus multilocularis cyclins 0.0166 0.0442 0.0601
Schistosoma mansoni twik family of potassium channels-related 0.0031 0.0001 0.0000093566
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0071 0.0133 0.0132
Loa Loa (eye worm) hypothetical protein 0.0297 0.0871 0.0871
Echinococcus granulosus cyclin A3 4 0.004 0.0031 0.0041
Entamoeba histolytica cysteine proteinase, putative 0.0607 0.1885 0.5021
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Plasmodium falciparum serine repeat antigen 7 0.0218 0.0611 0.1626
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0218 0.0611 0.7153
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.1244 0.3965 0.5394
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0218 0.0611 0.1053
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.0031 0.0031
Schistosoma mansoni neurotransmitter gated ion channel 0.0268 0.0777 0.1339
Brugia malayi hypothetical protein 0.0268 0.0777 0.0777
Loa Loa (eye worm) hypothetical protein 0.0218 0.0611 0.061
Trypanosoma brucei cyclin 9 0.004 0.0031 0.008
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0031 0.008
Entamoeba histolytica cysteine proteinase, putative 0.0607 0.1885 0.5021
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0611 0.1626
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0057 0.0663
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0057 0.0077
Echinococcus multilocularis tyrosine protein kinase ABL1 0.023 0.0651 0.0884
Loa Loa (eye worm) acetyltransferase 0.0149 0.0386 0.0385
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0582 0.1801 0.2449
Entamoeba histolytica cysteine protease, putative 0.0218 0.0611 0.1626
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0218 0.0611 0.7153
Echinococcus multilocularis cyclin G2 0.004 0.0031 0.0041
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.003
Giardia lamblia Hypothetical protein 0.004 0.0031 0.035
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.0611 0.1053
Entamoeba histolytica hypothetical protein 0.0035 0.0015 0.0039
Trypanosoma brucei cdc2-related kinase 1 0.0048 0.0057 0.0151
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0582 0.1801 0.18
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0789 0.248 0.6605
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0218 0.0611 0.1053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.0031 0.0031
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.1244 0.3965 0.5394
Entamoeba histolytica cysteine proteinase 2 0.0607 0.1885 0.5021
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0268 0.0777 0.0777
Echinococcus granulosus cathepsin b 0.0218 0.0611 0.083
Brugia malayi cathepsin Z-like cysteine proteinase 0.0218 0.0611 0.0611
Entamoeba histolytica cysteine proteinase, putative 0.0607 0.1885 0.5021
Echinococcus multilocularis potassium channel subfamily K 8 0.0031 0.0001 0.0000073788
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0582 0.1801 0.1801
Brugia malayi Cyclin, N-terminal domain containing protein 0.0292 0.0854 0.0854
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Echinococcus multilocularis short transient receptor potential channel 6 0.0065 0.0113 0.0152
Toxoplasma gondii hypothetical protein 0.0126 0.0311 0.0827
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1179 0.3754 0.3754
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0057 0.0098
Onchocerca volvulus 0.1179 0.3754 0.9469
Echinococcus multilocularis G1:S specific cyclin D1 0.004 0.0031 0.0041
Echinococcus multilocularis fibrillin 1 0.0063 0.0106 0.0143
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0119 0.0289 0.7011
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0046 0.0051 0.0134
Brugia malayi hypothetical protein 0.0268 0.0777 0.0777
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0607 0.1885 0.5021
Brugia malayi EGF-like domain containing protein 0.0063 0.0106 0.0106
Brugia malayi Cathepsin L-like precursor 0.1179 0.3754 0.3754
Brugia malayi Cathepsin L-like precursor 0.1179 0.3754 0.3754
Giardia lamblia Cyclin fold protein 1, putative 0.004 0.0031 0.035
Giardia lamblia Hypothetical protein 0.0218 0.0611 0.7153
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.004 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0313 0.0924 0.0923
Schistosoma mansoni cathepsin F (C01 family) 0.0789 0.248 0.4278
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0116 0.0277 0.0376
Echinococcus multilocularis cysteine protease 0.1179 0.3754 0.5107
Plasmodium vivax glutathione reductase, putative 0.0052 0.007 0.0185
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0031 0.0001 0.0000073788
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0789 0.248 0.6605
Trichomonas vaginalis hypothetical protein 0.0063 0.0106 0.028
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0218 0.0611 0.0611
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0218 0.0611 0.1626
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0607 0.1885 0.3252
Onchocerca volvulus 0.0063 0.0106 0.0265
Schistosoma mansoni cathepsin F (C01 family) 0.1179 0.3754 0.6476
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.0031 0.0031
Giardia lamblia Cathepsin L precursor 0.0218 0.0611 0.7153
Brugia malayi EGF-like domain containing protein 0.0063 0.0106 0.0106
Giardia lamblia Hypothetical protein 0.0166 0.0442 0.5174
Brugia malayi EGF-like domain containing protein 0.0063 0.0106 0.0106
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0031 0.0001 0.0000054233
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0031 0.008
Schistosoma mansoni hypothetical protein 0.0376 0.1129 0.1946
Giardia lamblia Cathepsin L precursor 0.0218 0.0611 0.7153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Echinococcus granulosus potassium channel subfamily K 8 0.0031 0.0001 0.0000073788
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0582 0.1801 0.1801
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0607 0.1885 0.5021
Mycobacterium tuberculosis Probable dehydrogenase 0.0119 0.0289 0.7011
Echinococcus granulosus adam 0.0063 0.0106 0.0143
Schistosoma mansoni twik family of potassium channels-related 0.0031 0.0001 0.0000093566
Echinococcus granulosus cyclin G2 0.004 0.0031 0.0041
Echinococcus multilocularis twik family of potassium channels 0.0031 0.0001 0.0000073788
Echinococcus multilocularis short transient receptor potential channel 6 0.0065 0.0113 0.0152
Schistosoma mansoni transient receptor potential channel 0.0065 0.0113 0.0193
Trichomonas vaginalis cyclin B, putative 0.0292 0.0854 0.2273
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Schistosoma mansoni integrin alpha 0.175 0.5619 0.9693
Schistosoma mansoni twik family of potassium channels-related 0.0031 0.0001 0.0000093566
Echinococcus multilocularis cathepsin b 0.0218 0.0611 0.083
Loa Loa (eye worm) hypothetical protein 0.0297 0.0871 0.0871
Loa Loa (eye worm) hypothetical protein 0.0218 0.0611 0.061
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.004 0.0031 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Echinococcus granulosus nAChR subunit 0.0582 0.1801 0.2449
Echinococcus multilocularis cathepsin b 0.0218 0.0611 0.083
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0049 0.0128
Plasmodium falciparum serine repeat antigen 6 0.0218 0.0611 0.1626
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0218 0.0611 0.1626
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Loa Loa (eye worm) hypothetical protein 0.039 0.1174 0.1173
Loa Loa (eye worm) hypothetical protein 0.0063 0.0106 0.0105
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0119 0.0289 0.7011
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0119 0.0289 0.7011
Giardia lamblia Cathepsin L precursor 0.0218 0.0611 0.7153
Echinococcus multilocularis integrin alpha ps 0.0784 0.2464 0.3351
Brugia malayi Protein kinase domain containing protein 0.0048 0.0057 0.0057
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0352 0.0478
Giardia lamblia Cysteine protease 0.0218 0.0611 0.7153
Giardia lamblia Kinase, CMGC CDK 0.0048 0.0057 0.0663
Echinococcus granulosus cathepsin L cysteine proteinase 0.1179 0.3754 0.5107
Loa Loa (eye worm) hypothetical protein 0.0042 0.0036 0.0035
Echinococcus granulosus integrin alpha 3 0.1341 0.4284 0.5828
Trypanosoma cruzi cyclin, putative 0.0292 0.0854 0.2273
Trypanosoma cruzi major cysteine proteinase, putative 0.0218 0.0611 0.1626
Schistosoma mansoni cathepsin B (C01 family) 0.0218 0.0611 0.1053
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Trichomonas vaginalis cyclin A, putative 0.004 0.0031 0.008
Brugia malayi Cation transporter family protein 0.0582 0.1801 0.1801
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1179 0.3754 0.3754
Loa Loa (eye worm) hypothetical protein 0.0063 0.0106 0.0105
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0049 0.0128
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0218 0.0611 0.1053
Trypanosoma cruzi CYC2-like cyclin, putative 0.0292 0.0854 0.2273
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.0611 0.1053
Loa Loa (eye worm) TK/ABL protein kinase 0.023 0.0651 0.065
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.0611 0.1053
Loa Loa (eye worm) cysteine protease 0.1179 0.3754 0.3754
Brugia malayi Papain family cysteine protease containing protein 0.0218 0.0611 0.0611
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0031 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0218 0.0611 0.061
Brugia malayi solute carrier family 40, member 1 0.0211 0.059 0.059
Giardia lamblia Cathepsin B precursor 0.0218 0.0611 0.7153
Schistosoma mansoni cathepsin S (C01 family) 0.0218 0.0611 0.1053
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.004 0.0031 0.008
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0218 0.0611 0.1626
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Echinococcus granulosus expressed conserved protein 0.0177 0.0477 0.0648
Onchocerca volvulus 0.0292 0.0854 0.2152
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0582 0.1801 0.3106
Leishmania major mitochondrial DNA polymerase beta 0.0297 0.0871 0.2318
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0049 0.0065
Echinococcus granulosus tyrosine protein kinase ABL1 0.023 0.0651 0.0884
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0132 0.0332 0.8068
Entamoeba histolytica cyclin, domain containing protein 0.004 0.0031 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Onchocerca volvulus 0.0582 0.1801 0.4541
Trypanosoma cruzi cysteine peptidase, putative 0.1179 0.3754 1
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0031 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1179 0.3754 1
Trypanosoma cruzi cysteine peptidase, putative 0.039 0.1174 0.3126
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0582 0.1801 0.2449
Loa Loa (eye worm) hypothetical protein 0.0313 0.0924 0.0923
Schistosoma mansoni integrin alpha-ps 0.0408 0.1235 0.2129
Echinococcus granulosus cyclin dependent kinase 5 0.0048 0.0057 0.0077
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0116 0.0277 0.0376
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1179 0.3754 1
Echinococcus granulosus integrin beta 2 0.2279 0.735 1
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0582 0.1801 0.1801
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Plasmodium vivax vivapain-2 0.1179 0.3754 1
Toxoplasma gondii cyclin 4, putative 0.004 0.0031 0.008
Echinococcus granulosus potassium channel subfamily K 8 0.0031 0.0001 0.0000073788
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.1244 0.3965 0.5394
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0411 1
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0031 0.0001 0.0000073788
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Echinococcus multilocularis Cyclin L1 0.004 0.0031 0.0041
Loa Loa (eye worm) hypothetical protein 0.007 0.0128 0.0127
Echinococcus multilocularis potassium channel subfamily K 8 0.0031 0.0001 0.0000073788
Schistosoma mansoni cathepsin C 0.0218 0.0611 0.1053
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0582 0.1801 0.1801
Plasmodium vivax hypothetical protein, conserved 0.004 0.0031 0.008
Entamoeba histolytica cysteine proteinase, putative 0.0789 0.248 0.6605
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0352 0.0478
Schistosoma mansoni hypothetical protein 0.004 0.0031 0.0052
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0218 0.0611 0.1626
Schistosoma mansoni hypothetical protein 0.004 0.0031 0.0052
Entamoeba histolytica cyclin family protein 0.0166 0.0442 0.1176
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0031 0.0001 0.0001
Onchocerca volvulus 0.1179 0.3754 0.9469
Brugia malayi Cation transporter family protein 0.0582 0.1801 0.1801
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0119 0.0289 0.7011
Brugia malayi Bromodomain containing protein 0.0085 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0313 0.0924 0.0923
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0607 0.1885 0.5021
Echinococcus granulosus cyclin dependent kinase 1 0.0048 0.0057 0.0077
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Trichomonas vaginalis cyclins, putative 0.0292 0.0854 0.2273
Echinococcus multilocularis protein jagged 2 0.0063 0.0106 0.0143
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0132 0.0332 1
Loa Loa (eye worm) GABA receptor subunit 0.0313 0.0924 0.0923
Onchocerca volvulus 0.0218 0.0611 0.154
Trichomonas vaginalis cyclins, putative 0.0292 0.0854 0.2273
Leishmania major cathepsin L-like protease 0.1179 0.3754 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0036 0.0035
Toxoplasma gondii cathepsin CPC1 0.0218 0.0611 0.1626
Brugia malayi cyclin fold protein 1 variant b 0.004 0.0031 0.0031
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.007 0.0185
Echinococcus multilocularis calcium activated potassium channel variant 0.0031 0.0001 0.0000073788
Loa Loa (eye worm) hypothetical protein 0.1374 0.439 0.4389
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0141 0.0359 0.0955
Brugia malayi Cathepsin L-like precursor 0.0789 0.248 0.248
Loa Loa (eye worm) hypothetical protein 0.0292 0.0854 0.0853
Echinococcus granulosus cyclin B 0.0292 0.0854 0.1161
Echinococcus granulosus cyclin 0.004 0.0031 0.0041
Onchocerca volvulus 0.0268 0.0777 0.1957
Loa Loa (eye worm) cathepsin B 0.0218 0.0611 0.061
Brugia malayi Papain family cysteine protease containing protein 0.0218 0.0611 0.0611
Giardia lamblia Cathepsin L-like protease 0.0218 0.0611 0.7153
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0051 0.0134
Trichomonas vaginalis cyclins, putative 0.0166 0.0442 0.1176
Schistosoma mansoni nAChR subunit 0.0268 0.0777 0.1339
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0313 0.0924 0.1593
Echinococcus multilocularis cyclin B 0.0292 0.0854 0.1161
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0063 0.0106 0.028
Echinococcus granulosus glycine receptor subunit beta 0.0582 0.1801 0.2449
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0031 0.0001 0.0001
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0031 0.0001 0.0001
Plasmodium falciparum cyclin 0.0166 0.0442 0.1176
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0031 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0408 0.1235 0.1234
Echinococcus granulosus expressed conserved protein 0.0091 0.0197 0.0267
Trypanosoma cruzi cysteine proteinase, putative 0.0607 0.1885 0.5021
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0036 0.0095
Brugia malayi Cytochrome P450 family protein 0.0035 0.0013 0.0013
Plasmodium falciparum protein kinase 5 0.0048 0.0057 0.0151
Giardia lamblia Hypothetical protein 0.004 0.0031 0.035
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0218 0.0611 0.1626
Echinococcus multilocularis glycine receptor subunit beta 0.0582 0.1801 0.2449
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0051 0.0134
Loa Loa (eye worm) hypothetical protein 0.0757 0.2375 0.2374
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0031 0.0001 0.0001
Brugia malayi Cell death protein 3 precursor 0.0031 0.0001 0.0001
Brugia malayi Cathepsin L-like precursor 0.1179 0.3754 0.3754
Leishmania major cathepsin L-like protease 0.1179 0.3754 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.0611 0.1053
Echinococcus multilocularis nAChR subunit 0.0313 0.0924 0.1256
Loa Loa (eye worm) hypothetical protein 0.0789 0.248 0.2479
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0218 0.0611 0.1626
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.0019
Echinococcus granulosus cyclin G2 0.004 0.0031 0.0041
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0218 0.0611 0.1053
Brugia malayi Protein kinase domain containing protein 0.0071 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Brugia malayi hypothetical protein 0.0031 0.0001 0.0001
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0031 0.0001 0.0001
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0582 0.1801 0.2449
Schistosoma mansoni calcium-activated potassium channel 0.0031 0.0001 0.0000093566
Loa Loa (eye worm) hypothetical protein 0.0062 0.0102 0.0101
Schistosoma mansoni nAChR subunit 0.0582 0.1801 0.3106
Entamoeba histolytica cysteine proteinase, putative 0.1179 0.3754 1
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0071 0.0133 0.0353
Loa Loa (eye worm) hypothetical protein 0.0285 0.0832 0.0831
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0216 0.0293
Onchocerca volvulus Cyclin L homolog 0.004 0.0031 0.0075
Echinococcus multilocularis glycine receptor subunit beta 0.0582 0.1801 0.2449
Echinococcus multilocularis cyclin 0.004 0.0031 0.0041
Brugia malayi Cyclin C 0.004 0.0031 0.0031
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0218 0.0611 0.1626
Schistosoma mansoni integrin alpha-ps 0.0784 0.2464 0.4249
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.0386 0.0665
Leishmania major cyclin 9, putative 0.004 0.0031 0.008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1179 0.3754 1
Schistosoma mansoni cyclin l 0.004 0.0031 0.0052
Echinococcus multilocularis expressed conserved protein 0.0091 0.0197 0.0267
Echinococcus multilocularis adam 0.0063 0.0106 0.0143
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0031 0.0001 0.0001
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0051 0.0051
Trypanosoma cruzi cysteine peptidase, putative 0.0607 0.1885 0.5021
Giardia lamblia Cathepsin B precursor 0.0218 0.0611 0.7153
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Schistosoma mansoni calcium-activated potassium channel 0.0031 0.0001 0.0000093566
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1179 0.3754 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0056 0.0055
Echinococcus multilocularis protein dispatched 1 0.0047 0.0055 0.0074
Plasmodium falciparum glutathione reductase 0.0052 0.007 0.0185
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0582 0.1801 0.18
Onchocerca volvulus 0.0582 0.1801 0.4541
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.004 0.0031 0.008
Echinococcus granulosus cathepsin l1 0.0789 0.248 0.3373
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0218 0.0611 0.1626
Echinococcus granulosus cyclin B3 1 0.0166 0.0442 0.0601
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0218 0.0611 0.1626
Entamoeba histolytica cysteine proteinase, putative 0.1179 0.3754 1
Loa Loa (eye worm) cyclin domain-containing protein 0.004 0.0031 0.003
Echinococcus granulosus G1:S specific cyclin D1 0.004 0.0031 0.0041
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0057 0.0151
Giardia lamblia Encystation-specific protease 0.0218 0.0611 0.7153
Schistosoma mansoni hypothetical protein 0.004 0.0031 0.0052
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.0031 0.0031
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0313 0.0924 0.0924
Brugia malayi hypothetical protein 0.0268 0.0777 0.0777
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0013 0.0012
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0015 0.002
Trichomonas vaginalis cyclin B3, putative 0.0166 0.0442 0.1176
Toxoplasma gondii hypothetical protein 0.0063 0.0106 0.028
Schistosoma mansoni hypothetical protein 0.004 0.0031 0.0052
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0031 0.0001 0.0001
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0582 0.1801 0.2449
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0031 0.0001 0.0001
Plasmodium falciparum serine repeat antigen 2 0.0218 0.0611 0.1626
Trichomonas vaginalis cyclin B, putative 0.0292 0.0854 0.2273
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0218 0.0611 0.1626
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Echinococcus multilocularis cyclins 0.0166 0.0442 0.0601
Brugia malayi fibroinase precursor 0.0218 0.0611 0.0611
Echinococcus granulosus cathepsin b 0.0218 0.0611 0.083
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0268 0.0777 0.1056
Brugia malayi cathepsin F-like cysteine proteinase 0.0218 0.0611 0.0611
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0582 0.1801 0.18
Plasmodium vivax vivapain-3 0.0607 0.1885 0.5021
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0057 0.0057
Onchocerca volvulus 0.0297 0.0871 0.2196
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0582 0.1801 0.1801
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0607 0.1885 0.5021
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0037 0.0019 0.0025
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0218 0.0611 0.1053
Loa Loa (eye worm) hypothetical protein 0.0047 0.0052 0.0052
Echinococcus granulosus caspase 3 0.0085 0.0176 0.0239
Brugia malayi hypothetical protein 0.0475 0.1453 0.1453
Echinococcus granulosus cathepsin L 0.0218 0.0611 0.083
Loa Loa (eye worm) TWK-7 protein 0.0031 0.0001 0.0000054233
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1179 0.3754 1
Brugia malayi Cathepsin L-like precursor 0.1179 0.3754 0.3754
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0979 0.3099 0.3099
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0068 0.0124 0.0167
Giardia lamblia Neurogenic locus Notch protein precursor 0.0063 0.0106 0.123
Giardia lamblia Cyclin A 0.0166 0.0442 0.5174
Leishmania major cathepsin L-like protease 0.1179 0.3754 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1179 0.3754 0.5107
Echinococcus granulosus glycine receptor subunit alpha 1 0.0582 0.1801 0.2449
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.1026 0.3252 0.561
Brugia malayi Bromodomain containing protein 0.0045 0.0048 0.0048
Schistosoma mansoni calcium-activated potassium channel 0.0859 0.2709 0.4673
Schistosoma mansoni neurotransmitter gated ion channel 0.0313 0.0924 0.1593
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Entamoeba histolytica cysteine protease, putative 0.0218 0.0611 0.1626
Schistosoma mansoni twik family of potassium channels-related 0.0031 0.0001 0.0000093566
Loa Loa (eye worm) hypothetical protein 0.0318 0.0939 0.0938
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Brugia malayi hypothetical protein 0.004 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0376 0.1129 0.1128
Plasmodium falciparum thioredoxin reductase 0.0052 0.007 0.0185
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0268 0.0777 0.1056
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.0611 0.1053
Brugia malayi Trypsin family protein 0.0297 0.0871 0.0871
Brugia malayi Cathepsin L-like precursor 0.1179 0.3754 0.3754
Entamoeba histolytica cyclin, domain containing protein 0.004 0.0031 0.008
Loa Loa (eye worm) ACC-1 protein 0.0582 0.1801 0.18
Echinococcus granulosus cyclin b3 0.0166 0.0442 0.0601
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0057 0.0151
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0302 0.0887 0.153
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0288 0.084 0.1142
Echinococcus multilocularis tyrosine protein kinase Abl 0.0094 0.0206 0.0279
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0068 0.0124 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0051 0.0134
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0268 0.0777 0.0776
Trypanosoma cruzi cyclin 9, putative 0.004 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0097 0.0216 0.0216
Loa Loa (eye worm) ctsf protein 0.1179 0.3754 0.3754
Trypanosoma brucei trypanothione reductase 0.0052 0.007 0.0185
Trichomonas vaginalis cyclin B, putative 0.004 0.0031 0.008
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.004 0.0031 0.0041
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0218 0.0611 0.1626
Echinococcus multilocularis transient receptor potential gamma protein 0.0098 0.0222 0.0301
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0133 0.0228
Loa Loa (eye worm) hypothetical protein 0.0965 0.3055 0.3054
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.004 0.0031 0.008
Giardia lamblia High cysteine protein 0.0063 0.0106 0.123
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0218 0.0611 0.1626
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Brugia malayi Cyclin, N-terminal domain containing protein 0.0292 0.0854 0.0854
Toxoplasma gondii hypothetical protein 0.0048 0.0056 0.0148
Trypanosoma cruzi major cysteine proteinase, putative 0.0218 0.0611 0.1626
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.004 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.1179 0.3754 0.3754
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0582 0.1801 0.1801
Schistosoma mansoni cyclin G 0.004 0.0031 0.0052
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0036 0.0047
Leishmania major mitotic cyclin, putative 0.004 0.0031 0.008
Giardia lamblia Tenascin-37 0.0063 0.0106 0.123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1179 0.3754 1
Brugia malayi hypothetical protein 0.0035 0.0015 0.0015
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0031 0.0001 0.0000054233
Mycobacterium tuberculosis Probable reductase 0.0119 0.0289 0.7011
Trypanosoma cruzi cysteine proteinase, putative 0.0607 0.1885 0.5021
Toxoplasma gondii cathepsin CPC2 0.0218 0.0611 0.1626
Loa Loa (eye worm) papain family cysteine protease containing protein 0.039 0.1174 0.1173
Onchocerca volvulus Cathepsin L homolog 0.0218 0.0611 0.154
Echinococcus granulosus cathepsin L 0.0607 0.1885 0.2564
Mycobacterium ulcerans hypothetical protein 0.0156 0.0411 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0106 0.0105
Toxoplasma gondii preprocathepsin c precursor, putative 0.0218 0.0611 0.1626
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0607 0.1885 0.3252
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.007 0.0094
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0607 0.1885 0.3252
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0048 0.0057 0.0077
Echinococcus multilocularis cyclin A3 4 0.004 0.0031 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1179 0.3754 1
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0218 0.0611 0.1626
Echinococcus multilocularis cyclins 0.0166 0.0442 0.0601
Schistosoma mansoni cyclin B 0.0292 0.0854 0.1472
Trichomonas vaginalis conserved hypothetical protein 0.0166 0.0442 0.1176
Loa Loa (eye worm) uncoordinated protein 58 0.0031 0.0001 0.0000054233
Onchocerca volvulus 0.0268 0.0777 0.1957
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0582 0.1801 0.2449
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.1026 0.3252 0.561
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Echinococcus granulosus cyclins 0.0166 0.0442 0.0601
Giardia lamblia G2/mitotic-specific cyclin B 0.0292 0.0854 1
Echinococcus multilocularis cathepsin L 0.0607 0.1885 0.2564
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0292 0.0854 0.2273
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0008
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0218 0.0611 0.1626
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0582 0.1801 0.1801
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0031 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0077 0.0151 0.015
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0031 0.0001 0.0001
Echinococcus multilocularis cyclins 0.0166 0.0442 0.0601
Loa Loa (eye worm) hypothetical protein 0.0313 0.0924 0.0923
Echinococcus granulosus cyclins 0.0166 0.0442 0.0601
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0582 0.1801 0.3106
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.0611 0.1053
Brugia malayi hypothetical protein 0.004 0.0031 0.0031
Entamoeba histolytica cyclin C, putative 0.004 0.0031 0.008
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0031 0.0001 0.0000054233
Brugia malayi EGF-like domain containing protein 0.0063 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0859 0.2709 0.2708
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0015 0.002
Giardia lamblia Cathepsin B precursor 0.0218 0.0611 0.7153
Schistosoma mansoni calcium-activated potassium channel 0.0603 0.1871 0.3227
Brugia malayi Kelch motif family protein 0.0475 0.1453 0.1453
Loa Loa (eye worm) hypothetical protein 0.005 0.0063 0.0062
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0582 0.1801 0.18
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0031 0.0001 0.0001
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0582 0.1801 0.2449
Loa Loa (eye worm) hypothetical protein 0.0218 0.0611 0.061
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.007 0.0185
Echinococcus granulosus tm gpcr rhodopsin 0.1535 0.4918 0.669
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0036 0.0047
Schistosoma mansoni nAChR subunit 0.0582 0.1801 0.3106
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0049 0.0128
Giardia lamblia Cathepsin L-like protease 0.0218 0.0611 0.7153
Echinococcus granulosus transient receptor potential ion channel A 0.0095 0.0211 0.0286
Loa Loa (eye worm) hypothetical protein 0.0087 0.0185 0.0184
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1179 0.3754 1
Onchocerca volvulus 0.0313 0.0924 0.2329
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0036 0.0095
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0051 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Entamoeba histolytica hypothetical protein 0.0218 0.0611 0.1626
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Loa Loa (eye worm) hypothetical protein 0.0225 0.0637 0.0636
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0133 0.0228
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0057 0.0151
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0268 0.0777 0.0776
Schistosoma mansoni cyclins 0.0166 0.0442 0.0762
Loa Loa (eye worm) integrin beta-2 0.309 1 1
Onchocerca volvulus 0.0211 0.059 0.1486
Schistosoma mansoni caspase-3 (C14 family) 0.0116 0.0277 0.0477
Trypanosoma cruzi cysteine peptidase, putative 0.1179 0.3754 1
Onchocerca volvulus 0.0272 0.0789 0.1988
Echinococcus multilocularis cyclin y 0.004 0.0031 0.0041
Schistosoma mansoni hypothetical protein 0.004 0.0031 0.0052
Echinococcus multilocularis cyclin b3 0.0166 0.0442 0.0601
Entamoeba histolytica cysteine protease, putative 0.0218 0.0611 0.1626
Plasmodium falciparum cysteine proteinase falcipain 3 0.1179 0.3754 1
Trypanosoma cruzi cruzipain precursor, putative 0.039 0.1174 0.3126
Onchocerca volvulus Cathepsin L homolog 0.1179 0.3754 0.9469
Trichomonas vaginalis cyclin B3, putative 0.004 0.0031 0.008
Echinococcus granulosus twik family of potassium channels 0.0031 0.0001 0.0000073788
Schistosoma mansoni patched 1 0.0042 0.0036 0.006
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0036 0.0095
Entamoeba histolytica hypothetical protein 0.0035 0.0015 0.0039
Loa Loa (eye worm) hypothetical protein 0.0313 0.0924 0.0923
Schistosoma mansoni acetylcholine receptor-related 0.0268 0.0777 0.1339
Onchocerca volvulus 0.0789 0.248 0.6254
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Schistosoma mansoni nAChR subunit 0.0268 0.0777 0.1339
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0582 0.1801 0.2449
Trypanosoma cruzi cdc2-related kinase 3 0.0048 0.0057 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Schistosoma mansoni twik family of potassium channels-related 0.0031 0.0001 0.0000093566
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0071 0.0133 0.0353
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1535 0.4918 0.669
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.1244 0.3965 0.3964
Echinococcus granulosus cyclin k 0.004 0.0031 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1179 0.3754 1
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0218 0.0611 0.1626
Giardia lamblia Cyclin B-like protein 0.004 0.0031 0.035
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Trichomonas vaginalis cyclin D, putative 0.0166 0.0442 0.1176
Echinococcus granulosus cyclin y 0.004 0.0031 0.0041
Loa Loa (eye worm) LGC-31 protein 0.0582 0.1801 0.18
Echinococcus multilocularis integrin alpha ps 0.0376 0.1129 0.1535
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0582 0.1801 0.3106
Leishmania major cysteine peptidase A (CPA) 0.1179 0.3754 1
Entamoeba histolytica cysteine proteinase 1, putative 0.0607 0.1885 0.5021
Loa Loa (eye worm) hypothetical protein 0.039 0.1174 0.1173
Giardia lamblia Cathepsin B precursor 0.0218 0.0611 0.7153
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0051 0.0069
Onchocerca volvulus 0.1026 0.3252 0.8201
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Echinococcus granulosus fibrillin 1 0.0063 0.0106 0.0143
Echinococcus granulosus cyclins 0.0166 0.0442 0.0601
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Trypanosoma cruzi cyclin 6, putative 0.0292 0.0854 0.2273
Onchocerca volvulus 0.1179 0.3754 0.9469
Leishmania major cathepsin L-like protease 0.1179 0.3754 1
Brugia malayi cathepsin L-like precursor 0.0789 0.248 0.248
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0268 0.0777 0.1056
Echinococcus multilocularis cyclin t1 0.004 0.0031 0.0041
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0288 0.084 0.1142
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.0611 0.1053
Plasmodium vivax unspecified product 0.0607 0.1885 0.5021
Echinococcus granulosus oligomeric golgi complex subunit 3 0.004 0.0031 0.0041
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Onchocerca volvulus 0.1179 0.3754 0.9469
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0218 0.0611 0.1626
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0029 0.0074
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0036 0.0047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1179 0.3754 1
Leishmania major cathepsin L-like protease 0.1179 0.3754 1
Echinococcus granulosus cathepsin l1 0.1179 0.3754 0.5107
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0046 0.0051 0.0087
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0046 0.0051 0.0591
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Giardia lamblia High cysteine protein 0.0063 0.0106 0.123
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0582 0.1801 0.1801
Loa Loa (eye worm) hypothetical protein 0.0313 0.0924 0.0923
Plasmodium falciparum cysteine proteinase falcipain 1 0.0607 0.1885 0.5021
Plasmodium falciparum cyclin 1 0.004 0.0031 0.008
Entamoeba histolytica hypothetical protein 0.0035 0.0015 0.0039
Onchocerca volvulus 0.1179 0.3754 0.9469
Loa Loa (eye worm) hypothetical protein 0.1244 0.3965 0.3964
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0582 0.1801 0.2449
Entamoeba histolytica cysteine protease, putative 0.0218 0.0611 0.1626
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0218 0.0611 0.1626
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.1244 0.3965 0.5394
Plasmodium vivax serine-repeat antigen (SERA) 0.0218 0.0611 0.1626
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0057 0.0151
Loa Loa (eye worm) glutathione reductase 0.0052 0.007 0.0069
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Trypanosoma cruzi cysteine peptidase, putative 0.1179 0.3754 1
Echinococcus granulosus twik family of potassium channels 0.0031 0.0001 0.0000073788
Schistosoma mansoni twik family of potassium channels-related 0.0031 0.0001 0.0000093566
Loa Loa (eye worm) cyclin domain-containing protein 0.004 0.0031 0.003
Onchocerca volvulus 0.1026 0.3252 0.8201
Echinococcus granulosus geminin 0.0184 0.0502 0.0682
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.004 0.0031 0.008
Echinococcus multilocularis cysteine protease 0.1179 0.3754 0.5107
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0031 0.0001 0.0001
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0297 0.0871 0.1502
Loa Loa (eye worm) hypothetical protein 0.0126 0.0312 0.0311
Echinococcus granulosus integrin alpha ps 0.0376 0.1129 0.1535
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0066 0.0174
Trichomonas vaginalis cyclins, putative 0.0292 0.0854 0.2273
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0268 0.0777 0.0777
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0475 0.1453 0.1453
Onchocerca volvulus 0.004 0.0031 0.0075
Echinococcus granulosus caspase 0.0116 0.0277 0.0376
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1179 0.3754 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0218 0.0611 0.1626
Entamoeba histolytica cysteine protease, putative 0.0218 0.0611 0.1626
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0268 0.0777 0.0777
Trypanosoma cruzi cysteine peptidase, putative 0.1179 0.3754 1
Schistosoma mansoni bromodomain containing protein 0.0072 0.0136 0.0234
Loa Loa (eye worm) integrin alpha pat-2 0.2352 0.7589 0.7589
Leishmania major mitotic cyclin, putative 0.004 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Echinococcus granulosus ubiquitin specific protease 41 0.0046 0.0051 0.0069
Plasmodium falciparum serine repeat antigen 5 0.0218 0.0611 0.1626
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0031 0.0001 0.0000073788
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0071 0.0133 0.0353
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Echinococcus granulosus dual specificity protein kinase clk2 0.0071 0.0133 0.018
Plasmodium falciparum serine repeat antigen 1 0.0218 0.0611 0.1626
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0218 0.0611 0.1626
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0313 0.0924 0.0924
Echinococcus granulosus short transient receptor potential channel 6 0.0065 0.0113 0.0152
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Brugia malayi follicle stimulating hormone receptor 0.0291 0.0853 0.0853
Schistosoma mansoni nAChR subunit 0.0582 0.1801 0.3106
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.1244 0.3965 0.5394
Echinococcus granulosus glycine receptor subunit alpha 1 0.0582 0.1801 0.2449
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0049 0.0128
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1179 0.3754 1
Onchocerca volvulus 0.1179 0.3754 0.9469
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Loa Loa (eye worm) hypothetical protein 0.0979 0.3099 0.3099
Loa Loa (eye worm) CYL-1 protein 0.004 0.0031 0.003
Echinococcus multilocularis caspase 0.0116 0.0277 0.0376
Schistosoma mansoni nAChR subunit 0.0582 0.1801 0.3106
Giardia lamblia Cysteine protease 0.0218 0.0611 0.7153
Giardia lamblia Cathepsin L precursor 0.0218 0.0611 0.7153
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1179 0.3754 1
Plasmodium falciparum serine repeat antigen 9 0.0218 0.0611 0.1626
Trypanosoma brucei mitotic cyclin 6 0.0292 0.0854 0.2273
Echinococcus multilocularis cyclin G2 0.004 0.0031 0.0041
Echinococcus multilocularis expressed conserved protein 0.0177 0.0477 0.0648
Leishmania major cathepsin L-like protease 0.1179 0.3754 1
Schistosoma mansoni twik family of potassium channels-related 0.0031 0.0001 0.0000093566
Loa Loa (eye worm) acetylcholine receptor protein 0.0268 0.0777 0.0776
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0098 0.0222 0.0221
Giardia lamblia Tenascin precursor 0.0063 0.0106 0.123
Brugia malayi hypothetical protein 0.0268 0.0777 0.0777
Brugia malayi CHE-14 protein 0.0042 0.0036 0.0036
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.0386 0.0524
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0364 0.0494
Trypanosoma brucei mitotic cyclin 0.004 0.0031 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0218 0.0611 0.1626
Onchocerca volvulus Protein CNPPD1 homolog 0.004 0.0031 0.0075
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0027 0.0036
Echinococcus granulosus cathepsin l cysteine peptidase 0.1179 0.3754 0.5107
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0048 0.0057 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0218 0.0611 0.1626
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0057 0.0151
Schistosoma mansoni hypothetical protein 0.0184 0.0502 0.0864
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0031 0.0001 0.0000073788
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0218 0.0611 0.1626
Trichomonas vaginalis CMGC family protein kinase 0.0071 0.0133 0.0353
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0029 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0211 0.059 0.0589
Echinococcus multilocularis cathepsin L 0.0218 0.0611 0.083
Echinococcus granulosus Cyclin L1 0.004 0.0031 0.0041
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0031 0.0001 0.0001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0582 0.1801 0.1801
Echinococcus multilocularis cyclins 0.0166 0.0442 0.0601
Schistosoma mansoni nAChR subunit 0.0582 0.1801 0.3106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0218 0.0611 0.1626
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0218 0.0611 0.1626
Trypanosoma cruzi mitotic cyclin, putative 0.004 0.0031 0.008
Echinococcus granulosus cyclins 0.004 0.0031 0.0041
Loa Loa (eye worm) hypothetical protein 0.039 0.1174 0.1173
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Loa Loa (eye worm) cyclin C 0.004 0.0031 0.003
Schistosoma mansoni neurotransmitter gated ion channel 0.0268 0.0777 0.1339
Trichomonas vaginalis cyclin B, putative 0.0166 0.0442 0.1176
Loa Loa (eye worm) cyclin domain-containing protein 0.004 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Trypanosoma cruzi mitotic cyclin, putative 0.004 0.0031 0.008
Echinococcus multilocularis cyclin dependent kinase 1 0.0048 0.0057 0.0077
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0291 0.0853 0.0852
Giardia lamblia Kinase, CMGC CLK 0.0071 0.0133 0.1551
Trichomonas vaginalis cyclin B, putative 0.0292 0.0854 0.2273
Loa Loa (eye worm) hypothetical protein 0.0475 0.1453 0.1453
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.039 0.1174 0.1174
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Brugia malayi Thioredoxin reductase 0.0052 0.007 0.007
Echinococcus multilocularis cathepsin L cysteine protease 0.1179 0.3754 0.5107
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0313 0.0924 0.0924
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0268 0.0777 0.1056
Schistosoma mansoni cyclin B3 0.0288 0.084 0.1447
Plasmodium vivax vivapain-2 0.1179 0.3754 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0218 0.0611 0.7153
Schistosoma mansoni transient receptor potential channel 0.0065 0.0113 0.0193
Trichomonas vaginalis cyclins, putative 0.0166 0.0442 0.1177
Entamoeba histolytica cysteine proteinase, putative 0.0607 0.1885 0.5021
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1179 0.3754 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0218 0.0611 0.1626
Entamoeba histolytica cysteine protease, putative 0.1179 0.3754 1
Onchocerca volvulus Cathepsin L homolog 0.1179 0.3754 0.9469
Onchocerca volvulus Putative nachr subunit 0.1244 0.3965 1
Brugia malayi cathepsin F-like cysteine proteinase 0.039 0.1174 0.1174
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0031 0.0001 0.0001
Trichomonas vaginalis cyclin B, putative 0.0292 0.0854 0.2273
Onchocerca volvulus Cyclin L homolog 0.004 0.0031 0.0075
Brugia malayi Cyclin, N-terminal domain containing protein 0.0288 0.084 0.084
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0132 0.0332 0.8068
Entamoeba histolytica hypothetical protein 0.004 0.0031 0.008
Trichomonas vaginalis cyclin D, putative 0.0166 0.0442 0.1176
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0046 0.0051 0.0069
Entamoeba histolytica hypothetical protein 0.0035 0.0015 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0218 0.0611 0.1626
Brugia malayi Papain family cysteine protease containing protein 0.0218 0.0611 0.0611
Loa Loa (eye worm) hypothetical protein 0.0313 0.0924 0.0923
Echinococcus granulosus small conductance calcium activated potassium 0.0859 0.2709 0.3685
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.007 0.1691
Loa Loa (eye worm) TWK-28 protein 0.0031 0.0001 0.0000054233
Echinococcus multilocularis integrin beta 2 0.2279 0.735 1
Schistosoma mansoni cyclin k 0.004 0.0031 0.0052
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0582 0.1801 0.3106
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0218 0.0611 0.1626
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0218 0.0611 0.1626
Brugia malayi Integrin alpha pat-2 precursor 0.175 0.5619 0.5619
Entamoeba histolytica cyclin, putative 0.0166 0.0442 0.1176
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.0031 0.0031
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.004 0.0031 0.0052
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.003
Echinococcus granulosus hypothetical protein 0.007 0.0128 0.0173
Plasmodium falciparum serine repeat antigen 3 0.0218 0.0611 0.1626
Plasmodium vivax serine/threonine kinase-1, putative 0.0071 0.0133 0.0353
Brugia malayi cathepsin L-like cysteine proteinase 0.0218 0.0611 0.0611
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1179 0.3754 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.007 0.0094
Giardia lamblia Cathepsin B precursor 0.0218 0.0611 0.7153
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0218 0.0611 0.1626
Brugia malayi Tyrosine-protein kinase abl-1 0.0139 0.0355 0.0355
Echinococcus multilocularis cyclin dependent kinase 5 0.0048 0.0057 0.0077
Echinococcus granulosus transient receptor potential gamma protein 0.0098 0.0222 0.0301
Toxoplasma gondii cathepsin CPL 0.1179 0.3754 1
Leishmania major cyclin 0.0292 0.0854 0.2273
Brugia malayi Cation transporter family protein 0.1026 0.3252 0.3252
Loa Loa (eye worm) cyclin domain-containing protein 0.0288 0.084 0.0839
Echinococcus granulosus cyclin dependent kinase 0.0048 0.0057 0.0077
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0051 0.0134
Brugia malayi Cathepsin L-like precursor 0.1179 0.3754 0.3754
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0051 0.0134
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0268 0.0777 0.0777
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Brugia malayi hypothetical protein 0.0031 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1179 0.3754 1
Entamoeba histolytica cyclin family protein 0.0166 0.0442 0.1176
Loa Loa (eye worm) hypothetical protein 0.0063 0.0106 0.0105
Plasmodium vivax unspecified product 0.0218 0.0611 0.1626
Echinococcus granulosus cyclins 0.0166 0.0442 0.0601
Brugia malayi cathepsin Z-like cysteine proteinase 0.0218 0.0611 0.0611
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0216 0.0574
Echinococcus multilocularis cyclin dependent kinase 0.0048 0.0057 0.0077
Brugia malayi glutathione reductase 0.0052 0.007 0.007
Echinococcus granulosus glycine receptor subunit alpha 1 0.0582 0.1801 0.2449
Mycobacterium tuberculosis Probable oxidoreductase 0.0132 0.0332 0.8068
Loa Loa (eye worm) hypothetical protein 0.0789 0.248 0.2479
Toxoplasma gondii cyclin dependent kinase binding protein 0.004 0.0031 0.008
Echinococcus multilocularis protein patched 0.0042 0.0036 0.0047
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0582 0.1801 0.1801
Giardia lamblia Hypothetical protein 0.0218 0.0611 0.7153
Trypanosoma cruzi cyclin, putative 0.0292 0.0854 0.2273
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0582 0.1801 0.1801
Echinococcus multilocularis potassium channel subfamily K 0.0031 0.0001 0.0000073788
Plasmodium vivax vivapain-1 0.0607 0.1885 0.5021
Schistosoma mansoni acetylcholine receptor subunit beta 0.0268 0.0777 0.1339
Schistosoma mansoni hypothetical protein 0.0031 0.0001 0.0000093566
Plasmodium falciparum serine repeat antigen 4 0.0218 0.0611 0.1626
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.0611 0.1053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1179 0.3754 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0066 0.0065
Echinococcus multilocularis ubiquitin specific protease 41 0.0046 0.0051 0.0069
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0071 0.0133 0.0353
Giardia lamblia Neurogenic locus notch-like protein 0.0063 0.0106 0.123
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.1244 0.3965 0.5394
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0051 0.0134
Giardia lamblia Cathepsin L precursor 0.0218 0.0611 0.7153
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0218 0.0611 0.1626
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0582 0.1801 0.1801
Loa Loa (eye worm) cyclin domain-containing protein 0.004 0.0031 0.003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0218 0.0611 0.061
Schistosoma mansoni transient receptor potential channel 4 0.0098 0.0222 0.0381
Plasmodium vivax unspecified product 0.039 0.1174 0.3126
Brugia malayi Cathepsin L-like precursor 0.039 0.1174 0.1174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Toxoplasma gondii hypothetical protein 0.004 0.0031 0.008
Leishmania major trypanothione reductase 0.0052 0.007 0.0185
Echinococcus multilocularis cyclin y 0.004 0.0031 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1179 0.3754 1
Schistosoma mansoni caspase-7 (C14 family) 0.0116 0.0277 0.0477
Echinococcus multilocularis integrin alpha ps 0.0784 0.2464 0.3351
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0216 0.0293
Trichomonas vaginalis conserved hypothetical protein 0.0218 0.0611 0.1626
Schistosoma mansoni cyclin d 0.004 0.0031 0.0052
Giardia lamblia Cysteine protease 0.0218 0.0611 0.7153
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0268 0.0777 0.1056
Echinococcus granulosus cyclin t1 0.004 0.0031 0.0041
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Trypanosoma cruzi cdc2-related kinase 1 0.0048 0.0057 0.0151
Schistosoma mansoni hypothetical protein 0.0184 0.0502 0.0864
Brugia malayi Papain family cysteine protease containing protein 0.0607 0.1885 0.1885
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0313 0.0924 0.1593
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Brugia malayi Transient-receptor-potential like protein 0.0037 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0582 0.1801 0.2449
Echinococcus granulosus glycine receptor subunit beta 0.0582 0.1801 0.2449
Echinococcus multilocularis caspase 3 0.0085 0.0176 0.0239
Schistosoma mansoni hypothetical protein 0.0035 0.0015 0.0025
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0218 0.0611 0.061
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.0871 0.2318
Onchocerca volvulus Cathepsin F homolog 0.1179 0.3754 0.9469
Giardia lamblia hypothetical protein 0.0063 0.0106 0.123
Schistosoma mansoni hypothetical protein 0.0859 0.2709 0.4673
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0036 0.0095
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0048 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0313 0.0924 0.0923
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0216 0.0216
Echinococcus multilocularis fibrillin 2 0.0063 0.0106 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Entamoeba histolytica cell division protein kinase 2, putative 0.0048 0.0057 0.0151
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.007 0.0069
Echinococcus multilocularis cyclin B3 1 0.0166 0.0442 0.0601
Echinococcus multilocularis cathepsin L cysteine protease 0.1179 0.3754 0.5107
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0582 0.1801 0.2449
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0221 0.038
Echinococcus multilocularis integrin alpha 3 0.1341 0.4284 0.5828
Trichomonas vaginalis cyclin A, putative 0.0292 0.0854 0.2273
Onchocerca volvulus 0.0582 0.1801 0.4541
Loa Loa (eye worm) hypothetical protein 0.0292 0.0854 0.0853
Schistosoma mansoni Cyclin fold protein 0.004 0.0031 0.0052
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0049 0.0128
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1179 0.3754 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Trichomonas vaginalis cyclin B3, putative 0.004 0.0031 0.008
Entamoeba histolytica hypothetical protein 0.0313 0.0924 0.2459
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.004 0.0031 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1179 0.3754 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1179 0.3754 1
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0048 0.0057 0.0151
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1179 0.3754 1
Leishmania major cathepsin L-like protease 0.1179 0.3754 1
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0057 0.0098
Loa Loa (eye worm) hypothetical protein 0.1026 0.3252 0.3251
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0268 0.0777 0.0777
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0582 0.1801 0.1801
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.0871 0.2318
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0029 0.0074
Loa Loa (eye worm) hypothetical protein 0.1026 0.3252 0.3251
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0046 0.0051 0.0069
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Echinococcus granulosus nAChR subunit 0.0313 0.0924 0.1256
Echinococcus granulosus short transient receptor potential channel 6 0.0065 0.0113 0.0152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1179 0.3754 1
Echinococcus granulosus integrin alpha ps 0.0784 0.2464 0.3351
Entamoeba histolytica cysteine protease, putative 0.0607 0.1885 0.5021
Brugia malayi cathepsin B-like cysteine proteinase 0.0218 0.0611 0.0611
Loa Loa (eye worm) cyclin domain-containing protein 0.004 0.0031 0.003
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0218 0.0611 0.1626
Echinococcus granulosus cysteine protease 0.0607 0.1885 0.2564
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0218 0.0611 0.1626
Echinococcus granulosus cyclins 0.0166 0.0442 0.0601
Schistosoma mansoni cathepsin F (C01 family) 0.1179 0.3754 0.6476
Schistosoma mansoni hypothetical protein 0.004 0.0031 0.0052
Brugia malayi Papain family cysteine protease containing protein 0.1179 0.3754 0.3754
Loa Loa (eye worm) hypothetical protein 0.0789 0.248 0.2479
Plasmodium vivax cyclin 4, putative 0.004 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Trypanosoma cruzi cysteine protease, putative 0.0607 0.1885 0.5021
Onchocerca volvulus 0.0313 0.0924 0.2329
Plasmodium falciparum serine repeat antigen 8 0.0218 0.0611 0.1626
Brugia malayi hypothetical protein 0.0268 0.0777 0.0777
Brugia malayi Cyclin, N-terminal domain containing protein 0.004 0.0031 0.0031
Schistosoma mansoni tyrosine kinase 0.0226 0.064 0.1103
Echinococcus multilocularis 0.007 0.0128 0.0173
Echinococcus granulosus TRP transient receptor potential channel 0.0037 0.0019 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0218 0.0611 0.1626
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0218 0.0611 0.1626
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Echinococcus granulosus cathepsin L cysteine protease 0.0607 0.1885 0.2564
Loa Loa (eye worm) hypothetical protein 0.0268 0.0777 0.0776
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0071 0.0133 0.0353
Plasmodium vivax protein kinase Crk2 0.0048 0.0057 0.0151
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0582 0.1801 0.2449
Schistosoma mansoni g1/s-specific cyclin C 0.004 0.0031 0.0052
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0268 0.0777 0.0777
Echinococcus multilocularis cyclins 0.0166 0.0442 0.0601
Toxoplasma gondii cathepsin B 0.0218 0.0611 0.1626
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1179 0.3754 1
Brugia malayi cathepsin L precursor 0.0218 0.0611 0.0611
Schistosoma mansoni integrin beta subunit 0.1804 0.5797 1
Loa Loa (eye worm) hypothetical protein 0.0582 0.1801 0.18
Trichomonas vaginalis cyclin D, putative 0.004 0.0031 0.008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0218 0.0611 0.1053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0218 0.0611 0.1626
Echinococcus granulosus calcium activated potassium channel variant 0.0031 0.0001 0.0000073788
Giardia lamblia Tenascin-X 0.0063 0.0106 0.123
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0057 0.0151
Echinococcus granulosus fibrillin 2 0.0063 0.0106 0.0143
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Echinococcus granulosus cyclin y 0.004 0.0031 0.0041
Trypanosoma brucei cyclin 3 0.004 0.0031 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0218 0.0611 0.1626
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0218 0.0611 0.061
Trypanosoma brucei cdc2-related kinase 3 0.0048 0.0057 0.0151
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.004 0.0031 0.0041
Giardia lamblia Cathepsin B precursor 0.0218 0.0611 0.7153
Loa Loa (eye worm) hypothetical protein 0.0031 0.0001 0.0000054233
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0036 0.0093
Loa Loa (eye worm) cyclin domain-containing protein 0.004 0.0031 0.003
Plasmodium falciparum protein serine/threonine kinase-1 0.0071 0.0133 0.0353
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0789 0.248 0.6605
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.1244 0.3965 0.3965

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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