TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 307.37 | Formula: C17H13N3OS
H donors: 1 H acceptors: 2 LogP: 3.9 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: COc1cccc(c1)c1ccc2c(c1)sc1c2ncnc1N
InChi: 1S/C17H13N3OS/c1-21-12-4-2-3-10(7-12)11-5-6-13-14(8-11)22-16-15(13)19-9-20-17(16)18/h2-9H,1H3,(H2,18,19,20)
InChiKey: YJTCYKKMMVLKHB-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	LIM domain kinase 1	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma japonicum	ko:K05743 LIM domain kinase 1, putative	Get druggable targets OG5_131191	All targets in OG5_131191
Echinococcus granulosus	dual specificity testis-specific protein kinase	Get druggable targets OG5_131191	All targets in OG5_131191
Schistosoma mansoni	protein kinase	Get druggable targets OG5_131191	All targets in OG5_131191
Echinococcus multilocularis	dual specificity testis specific protein kinase	Get druggable targets OG5_131191	All targets in OG5_131191
Schistosoma mansoni	protein kinase	Get druggable targets OG5_131191	All targets in OG5_131191

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	tyrosine protein kinase Srms	0.0154	0.3618	0.3587
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Loa Loa (eye worm)	TK protein kinase	0.0186	0.4495	0.5884
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0123	0.2744	0.3567
Brugia malayi	Src substrate cortactin	0.0111	0.2415	0.3131
Trichomonas vaginalis	conserved hypothetical protein	0.0111	0.2415	1
Trichomonas vaginalis	CMGC family protein kinase	0.0057	0.089	0.3687
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0035	0.0278	0.0303
Entamoeba histolytica	unconventional myosin IB	0.0111	0.2415	0.6628
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0035	0.0278	0.0303
Echinococcus multilocularis	rho guanine nucleotide exchange factor 7	0.0111	0.2415	0.2377
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Entamoeba histolytica	protein kinase, putative	0.0066	0.1155	0.3097
Brugia malayi	RhoGAP domain containing protein	0.0126	0.2826	0.3676
Loa Loa (eye worm)	hypothetical protein	0.0122	0.2706	0.3517
Brugia malayi	p70 ribosomal S6 kinase beta	0.0045	0.0554	0.0669
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Trichomonas vaginalis	CMGC family protein kinase	0.0057	0.089	0.3687
Onchocerca volvulus	Putative cortactin	0.0111	0.2415	0.4978
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Trichomonas vaginalis	conserved hypothetical protein	0.0035	0.0278	0.1152
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0297	0.7604	0.7593
Trypanosoma brucei	cdc2-related kinase 1	0.0048	0.0656	0.2564
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0297	0.7604	0.7593
Entamoeba histolytica	serine/threonine kinase, putative	0.0035	0.0278	0.0642
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0035	0.0278	0.0303
Schistosoma mansoni	dreadlocks/dock	0.0111	0.2415	0.2377
Onchocerca volvulus		0.012	0.2645	0.5514
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Brugia malayi	C-terminal src kinase protein 1	0.0035	0.0278	0.0303
Schistosoma mansoni	development and differentiation-enhancing factor ddef	0.0114	0.2476	0.2439
Loa Loa (eye worm)	hypothetical protein	0.0111	0.2415	0.3131
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Loa Loa (eye worm)	AGC/PKC/ALPHA protein kinase	0.0046	0.0596	0.0723
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0035	0.0278	0.0303
Entamoeba histolytica	serine/threonine kinase, putative	0.0035	0.0278	0.0642
Echinococcus granulosus	hypothetical protein	0.012	0.2645	0.2609
Entamoeba histolytica	ankyrin repeat protein	0.0035	0.0278	0.0642
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0035	0.0278	0.023
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0035	0.0278	0.023
Onchocerca volvulus		0.0116	0.2551	0.5295
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0035	0.0278	0.023
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0041	0.046	0.0413
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Echinococcus multilocularis	tyrosine protein kinase shark	0.0383	1	1
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Trypanosoma cruzi	cdc2-related kinase 3	0.0048	0.0656	0.256
Brugia malayi	Protein kinase domain containing protein	0.0047	0.0616	0.0751
Echinococcus granulosus	guanine nucleotide exchange factor VAV2	0.0126	0.2826	0.2791
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Plasmodium falciparum	tyrosine kinase-like protein	0.0035	0.0278	0.3777
Echinococcus granulosus	expressed conserved protein	0.012	0.2645	0.2609
Echinococcus granulosus	SH2 domain containing protein 7	0.012	0.2645	0.2609
Loa Loa (eye worm)	TK/EPH protein kinase	0.0035	0.0278	0.0303
Echinococcus granulosus	tyrosine kinase	0.0186	0.4495	0.4467
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0224	0.5562	0.554
Plasmodium falciparum	tyrosine kinase-like protein	0.0035	0.0278	0.3777
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Trichomonas vaginalis	STE family protein kinase	0.0082	0.159	0.6585
Schistosoma mansoni	tensin-related	0.012	0.2645	0.2609
Trichomonas vaginalis	STE family protein kinase	0.0082	0.159	0.6585
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0035	0.0278	0.023
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus granulosus	tyrosine protein kinase pr2	0.0035	0.0278	0.023
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Echinococcus granulosus	tyrosine kinase	0.0154	0.3618	0.3587
Entamoeba histolytica	hypothetical protein	0.0111	0.2415	0.6628
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Leishmania major	cell division protein kinase 2,cdc2-related kinase	0.0048	0.0656	0.2564
Onchocerca volvulus		0.0154	0.3618	0.7782
Brugia malayi	SH2 domain containing protein	0.0188	0.457	0.5984
Brugia malayi	Sex muscle abnormal protein 5	0.0231	0.5755	0.7552
Schistosoma mansoni	tensin	0.012	0.2645	0.2609
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0035	0.0278	0.023
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0035	0.0278	0.0303
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Echinococcus multilocularis	hematopoietic lineage cell specific protein	0.0111	0.2415	0.2377
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0278	0.0303
Trypanosoma cruzi	hypothetical protein, conserved	0.0111	0.2415	1
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Trichomonas vaginalis	STE family protein kinase	0.0082	0.159	0.6585
Schistosoma mansoni	hypothetical protein	0.012	0.2645	0.2609
Brugia malayi	Protein kinase domain containing protein	0.0154	0.3618	0.4724
Toxoplasma gondii	cell-cycle-associated protein kinase CDK, putative	0.0048	0.0656	0.721
Trichomonas vaginalis	conserved hypothetical protein	0.0111	0.2415	1
Trypanosoma cruzi	cdc2-related kinase 3	0.0048	0.0656	0.256
Echinococcus granulosus	cyclin dependent kinase 1	0.0048	0.0656	0.061
Brugia malayi	Variant SH3 domain containing protein	0.0231	0.5755	0.7552
Schistosoma mansoni	signal transducing adapter molecule (stam)	0.0111	0.2415	0.2377
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Schistosoma mansoni	protein kinase	0.0035	0.0278	0.023
Loa Loa (eye worm)	AGC/AKT protein kinase	0.0047	0.0616	0.0751
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.012	0.2645	0.2609
Brugia malayi	SH3 domain containing protein	0.0111	0.2415	0.3131
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0266	0.6728	0.6712
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Brugia malayi	Tyrosine-protein kinase abl-1	0.0266	0.6728	0.884
Echinococcus multilocularis	heat shock protein 70	0.0035	0.0278	0.023
Brugia malayi	SRC-1	0.0297	0.7604	1
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Schistosoma mansoni	protein kinase	0.0082	0.159	0.1549
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Onchocerca volvulus	LIM and SH3 domain protein homolog	0.0111	0.2417	0.4985
Entamoeba histolytica	hypothetical protein	0.0035	0.0278	0.0642
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Brugia malayi	hypothetical protein	0.0154	0.3618	0.4724
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0035	0.0278	0.2724
Brugia malayi	Protein kinase domain containing protein	0.0154	0.3618	0.4724
Brugia malayi	Tyrosine-protein kinase PR2	0.0035	0.0278	0.0303
Entamoeba histolytica	tyrosin kinase, putative	0.0035	0.0278	0.0642
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0035	0.0278	0.023
Echinococcus multilocularis	nostrin	0.0111	0.2415	0.2377
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0035	0.0278	0.1152
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0035	0.0278	0.023
Echinococcus multilocularis	protein tyrosine kinase	0.0035	0.0278	0.023
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0066	0.1155	0.1111
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Echinococcus granulosus	protein kinase c epsilon type	0.0031	0.0158	0.0109
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Brugia malayi	Myosin tail family protein	0.0111	0.2415	0.3131
Echinococcus multilocularis	tyrosine protein kinase	0.0035	0.0278	0.023
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Trypanosoma brucei	mitogen-activated protein kinase kinase 5	0.0082	0.159	0.6514
Loa Loa (eye worm)	thyroid receptor interactor	0.0111	0.2415	0.3131
Onchocerca volvulus		0.0111	0.2415	0.4978
Echinococcus multilocularis	insulin receptor	0.0035	0.0278	0.023
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0035	0.0278	0.0642
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus multilocularis	activin receptor type	0.0037	0.0346	0.0298
Brugia malayi	Spectrin alpha chain	0.0111	0.2415	0.3131
Loa Loa (eye worm)	TK/FER protein kinase	0.0154	0.3618	0.4724
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0224	0.5562	0.554
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0035	0.0278	0.0303
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0278	0.0303
Brugia malayi	SH2 domain containing protein	0.012	0.2645	0.3436
Schistosoma mansoni	tyrosine kinase	0.0297	0.7604	0.7593
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0035	0.0278	0.1152
Echinococcus granulosus	tensin	0.012	0.2645	0.2609
Trypanosoma cruzi	hypothetical protein, conserved	0.0111	0.2415	1
Entamoeba histolytica	protein kinase, putative	0.0047	0.0616	0.1589
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0035	0.0278	0.1152
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Trichomonas vaginalis	conserved hypothetical protein	0.0111	0.2415	1
Onchocerca volvulus		0.0188	0.457	1
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Echinococcus granulosus	Spectrin alpha actinin	0.0111	0.2415	0.2377
Trichomonas vaginalis	conserved hypothetical protein	0.0035	0.0278	0.1152
Entamoeba histolytica	SH2 domain containing protein	0.012	0.2645	0.7273
Echinococcus granulosus	breast cancer anti estrogen resistance protein	0.0111	0.2415	0.2377
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Toxoplasma gondii	STE kinase	0.0035	0.0278	0.2724
Echinococcus granulosus	signal transduction protein lnk realted	0.012	0.2645	0.2609
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0035	0.0278	0.023
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0297	0.7604	0.7593
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0186	0.4495	0.4467
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0278	0.0303
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0278	0.0303
Echinococcus multilocularis	endophilin A3	0.0111	0.2415	0.2377
Echinococcus granulosus	SH2 domain containing adapter protein F	0.012	0.2645	0.2609
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Brugia malayi	hypothetical protein	0.0035	0.0278	0.0303
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0035	0.0278	0.023
Schistosoma mansoni	tyrosine kinase	0.0266	0.6728	0.6712
Trichomonas vaginalis	AGC family protein kinase	0.0047	0.0616	0.2551
Loa Loa (eye worm)	TK protein kinase	0.0035	0.0278	0.0303
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0035	0.0278	0.0303
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0035	0.0278	0.0642
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Schistosoma mansoni	serine/threonine protein kinase	0.0073	0.1343	0.13
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Entamoeba histolytica	cell division protein kinase 2, putative	0.0048	0.0656	0.17
Schistosoma mansoni	serine/threonine protein kinase	0.0035	0.0278	0.023
Brugia malayi	SH2 domain containing protein	0.012	0.2645	0.3436
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0035	0.0278	0.023
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Trypanosoma cruzi	mitogen activated protein kinase 2, putative	0.0057	0.089	0.3552
Loa Loa (eye worm)	hypothetical protein	0.0111	0.2415	0.3131
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0278	0.0303
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0297	0.7604	0.7593
Toxoplasma gondii	protein kinase domain-containing protein	0.0035	0.0278	0.2724
Brugia malayi	ephrin receptor 1 precursor	0.0035	0.0278	0.0303
Echinococcus granulosus	mitogen activated protein kinase 3	0.0057	0.089	0.0845
Loa Loa (eye worm)	serine/threonine protein kinase	0.0035	0.0278	0.0303
Schistosoma mansoni	serine/threonine protein kinase	0.0146	0.3388	0.3356
Entamoeba histolytica	hypothetical protein	0.0035	0.0278	0.0642
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Schistosoma mansoni	signal transduction protein lnk-related	0.012	0.2645	0.2609
Echinococcus multilocularis	breast cancer anti estrogen resistance protein	0.0111	0.2415	0.2377
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0035	0.0278	0.023
Echinococcus multilocularis	epidermal growth factor receptor kinase	0.0111	0.2415	0.2377
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0035	0.0278	0.0969
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Schistosoma mansoni	sorbin	0.0111	0.2415	0.2377
Echinococcus multilocularis	dual specificity mitogen activated protein	0.0082	0.159	0.1549
Echinococcus granulosus	hematopoietic lineage cell specific protein	0.0111	0.2415	0.2377
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Entamoeba histolytica	protein kinase, putative	0.0045	0.0554	0.1416
Brugia malayi	tRNA modification GTPase TrmE family protein	0.012	0.2645	0.3436
Brugia malayi	Fes/CIP4 homology domain containing protein	0.0111	0.2415	0.3131
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0186	0.4495	0.4467
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Entamoeba histolytica	hypothetical protein	0.0035	0.0278	0.0642
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0035	0.0278	0.023
Trichomonas vaginalis	AGC family protein kinase	0.0035	0.0278	0.1152
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0151	0.3521	0.3489
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Brugia malayi	Guanylyl cyclase protein 23	0.0035	0.0278	0.0303
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Echinococcus multilocularis	FL cytokine receptor	0.0035	0.0278	0.023
Entamoeba histolytica	tyrosin kinase, putative	0.0035	0.0278	0.0642
Toxoplasma gondii	AGC kinase	0.0045	0.0554	0.6007
Trichomonas vaginalis	conserved hypothetical protein	0.0035	0.0278	0.1152
Brugia malayi	Variant SH3 domain containing protein	0.0111	0.2415	0.3131
Echinococcus multilocularis	slit robo rho gtpase activating protein 1	0.0111	0.2415	0.2377
Echinococcus multilocularis	cyclin dependent kinase	0.0048	0.0656	0.061
Loa Loa (eye worm)	TK protein kinase	0.0035	0.0278	0.0303
Echinococcus granulosus	endophilin A3	0.0111	0.2415	0.2377
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0154	0.3618	0.3587
Trichomonas vaginalis	conserved hypothetical protein	0.0035	0.0278	0.1152
Echinococcus multilocularis	SH2 motif	0.012	0.2645	0.2609
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0035	0.0278	0.3777
Echinococcus multilocularis	tensin	0.012	0.2645	0.2609
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0035	0.0278	0.023
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0035	0.0278	0.023
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Echinococcus granulosus	SHC transforming protein 3	0.012	0.2645	0.2609
Echinococcus multilocularis	SH2 motif	0.012	0.2645	0.2609
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0266	0.6728	0.6712
Schistosoma mansoni	protein tyrosine kinase	0.0035	0.0278	0.023
Onchocerca volvulus		0.012	0.2645	0.5514
Trichomonas vaginalis	AGC family protein kinase	0.0047	0.0616	0.2551
Loa Loa (eye worm)	TK protein kinase	0.0035	0.0278	0.0303
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.012	0.2645	0.2609
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0035	0.0278	0.023
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Schistosoma mansoni	protein kinase	0.0035	0.0278	0.023
Echinococcus multilocularis	Spectrin alpha actinin	0.0111	0.2415	0.2377
Brugia malayi	Variant SH3 domain containing protein	0.0111	0.2415	0.3131
Brugia malayi	Protein kinase domain containing protein	0.0048	0.0656	0.0803
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Echinococcus multilocularis	tyrosine kinase	0.0154	0.3618	0.3587
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Echinococcus granulosus	activin receptor type	0.0037	0.0346	0.0298
Schistosoma mansoni	tyrosine kinase	0.03	0.768	0.7669
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.012	0.2645	0.2609
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Loa Loa (eye worm)	SH2 domain-containing protein	0.012	0.2645	0.3436
Echinococcus granulosus	receptor type guanylyl cyclase	0.0035	0.0278	0.023
Echinococcus granulosus	epidermal growth factor receptor	0.0035	0.0278	0.023
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Schistosoma mansoni	tensin	0.012	0.2645	0.2609
Echinococcus granulosus	activated cdc42 kinase 1	0.0035	0.0278	0.023
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0186	0.4495	0.4467
Brugia malayi	STAT protein, DNA binding domain containing protein	0.012	0.2645	0.3436
Echinococcus multilocularis	arf GAP with SH3 domain, ANK repeat and PH	0.0114	0.2476	0.2439
Trichomonas vaginalis	CMGC family protein kinase	0.0048	0.0656	0.2715
Loa Loa (eye worm)	TK/DDR protein kinase	0.0035	0.0278	0.0303
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0154	0.3618	0.3587
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Entamoeba histolytica	hypothetical protein	0.0114	0.2476	0.6801
Loa Loa (eye worm)	TK protein kinase	0.0035	0.0278	0.0303
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Entamoeba histolytica	hypothetical protein	0.0035	0.0278	0.0642
Onchocerca volvulus		0.012	0.2645	0.5514
Brugia malayi	Peripheral plasma membrane protein CASK	0.0114	0.2483	0.3221
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Brugia malayi	Protein kinase domain containing protein	0.0154	0.3618	0.4724
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0111	0.2415	0.3131
Schistosoma mansoni	adapter molecule crk	0.0231	0.5755	0.5734
Echinococcus granulosus	kinase suppressor of Ras 1	0.0035	0.0278	0.023
Loa Loa (eye worm)	TK/FER protein kinase	0.0154	0.3618	0.4724
Loa Loa (eye worm)	sex muscle abnormal protein 5	0.0231	0.5755	0.7552
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0297	0.7604	0.7593
Loa Loa (eye worm)	SH2 domain-containing protein	0.012	0.2645	0.3436
Schistosoma mansoni	dynamin-associated protein	0.0111	0.2415	0.2377
Schistosoma mansoni	ephrin receptor	0.0035	0.0278	0.023
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Loa Loa (eye worm)	STE/STE7/MEK1 protein kinase	0.0082	0.159	0.204
Loa Loa (eye worm)	TK/INSR protein kinase	0.0035	0.0278	0.0303
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Loa Loa (eye worm)	SRC-1	0.0297	0.7604	1
Trichomonas vaginalis	conserved hypothetical protein	0.0111	0.2415	1
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Leishmania major	mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860	0.0082	0.159	0.6514
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Leishmania major	mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440	0.0057	0.089	0.3556
Loa Loa (eye worm)	p53BP2	0.0111	0.2415	0.3131
Echinococcus multilocularis	epidermal growth factor receptor	0.0035	0.0278	0.023
Loa Loa (eye worm)	TK/ACK protein kinase	0.0035	0.0278	0.0303
Trypanosoma cruzi	mitogen-activated protein kinase kinase 5	0.0082	0.159	0.6512
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0297	0.7604	0.7593
Echinococcus multilocularis	tyrosine kinase	0.0035	0.0278	0.023
Schistosoma mansoni	sorting nexin	0.0111	0.2415	0.2377
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Echinococcus multilocularis	tyrosine protein kinase csk	0.0069	0.123	0.1187
Trypanosoma brucei	cdc2-related kinase 3	0.0048	0.0656	0.2564
Entamoeba histolytica	hypothetical protein	0.0035	0.0278	0.0642
Echinococcus granulosus	tensin C1 domain containing phosphatase	0.012	0.2645	0.2609
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0278	0.0303
Echinococcus multilocularis	tyrosine protein kinase csk	0.0069	0.123	0.1187
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Schistosoma mansoni	hypothetical protein	0.0111	0.2415	0.2377
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Echinococcus granulosus	tyrosine protein kinase Blk	0.0186	0.4495	0.4467
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Schistosoma mansoni	serine/threonine protein kinase	0.0048	0.0656	0.061
Echinococcus multilocularis	phosphatidylinositol 3 kinase regulatory subunit	0.012	0.2645	0.2609
Schistosoma mansoni	C-fyn	0.0111	0.2415	0.2377
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0035	0.0278	0.023
Entamoeba histolytica	hypothetical protein, conserved	0.0035	0.0278	0.0642
Schistosoma mansoni	tyrosine kinase	0.0297	0.7604	0.7593
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0027	0.005	0.0004
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Echinococcus granulosus	SH2 motif	0.012	0.2645	0.2609
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0035	0.0278	0.023
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Plasmodium vivax	protein kinase Crk2	0.0048	0.0656	1
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Loa Loa (eye worm)	TK/FER protein kinase	0.0154	0.3618	0.4724
Schistosoma mansoni	sh3-containing grb2-like protein 1 (endophilin II)	0.0111	0.2415	0.2377
Onchocerca volvulus		0.0111	0.2415	0.4978
Echinococcus granulosus	SH2 motif	0.012	0.2645	0.2609
Schistosoma mansoni	protein kinase	0.0035	0.0278	0.023
Loa Loa (eye worm)	hypothetical protein	0.0111	0.2415	0.3131
Echinococcus multilocularis	protein kinase c iota type	0.0029	0.012	0.0071
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0035	0.0278	0.0303
Trichomonas vaginalis	neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative	0.0111	0.2415	1
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0278	0.0303
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0126	0.2826	0.2791
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Loa Loa (eye worm)	cytokine inducible SH2-containing protein 5	0.012	0.2645	0.3436
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0057	0.089	0.3552
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.012	0.2645	0.3436
Entamoeba histolytica	hypothetical protein	0.0111	0.2415	0.6628
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0048	0.0656	0.0803
Toxoplasma gondii	CMGC kinase, MAPK family (ERK) MAPK-1	0.0057	0.089	1
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0035	0.0278	0.023
Echinococcus granulosus	epidermal growth factor receptor kinase	0.0111	0.2415	0.2377
Entamoeba histolytica	hypothetical protein	0.0035	0.0278	0.0642
Schistosoma mansoni	tyrosine-protein kinase zap-70	0.012	0.2645	0.2609
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0297	0.7604	0.7593
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Trypanosoma cruzi	hypothetical protein, conserved	0.0111	0.2415	1
Schistosoma mansoni	Dab2-interacting protein-like	0.0111	0.2415	0.2377
Schistosoma mansoni	serine/threonine protein kinase	0.0057	0.089	0.0845
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Brugia malayi	Guanylate kinase family protein	0.0114	0.2483	0.3221
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Loa Loa (eye worm)	hypothetical protein	0.0111	0.2417	0.3135
Schistosoma mansoni	nck2/grb4	0.0231	0.5755	0.5734
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Trichomonas vaginalis	AGC family protein kinase	0.0047	0.0616	0.2551
Loa Loa (eye worm)	protein kinase C and casein kinase substrate in neurons protein 2	0.0111	0.2415	0.3131
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0297	0.7604	0.7593
Plasmodium vivax	protein kinase, putative	0.0035	0.0278	0.3777
Trichomonas vaginalis	conserved hypothetical protein	0.0035	0.0278	0.1152
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0035	0.0278	0.023
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Echinococcus granulosus	mitogen activated protein kinase	0.0057	0.089	0.0845
Echinococcus granulosus	intersectin 2	0.0113	0.2452	0.2415
Echinococcus granulosus	growth factor receptor bound protein 2	0.0231	0.5755	0.5734
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0278	0.0303
Echinococcus granulosus	N chimaerin	0.0126	0.2826	0.2791
Trichomonas vaginalis	CMGC family protein kinase	0.0057	0.089	0.3687
Loa Loa (eye worm)	hypothetical protein	0.0111	0.2415	0.3131
Brugia malayi	Protein kinase domain containing protein	0.0154	0.3618	0.4724
Echinococcus granulosus	activated cdc42 kinase 1	0.0035	0.0278	0.023
Echinococcus multilocularis	signal transduction protein lnk realted	0.012	0.2645	0.2609
Onchocerca volvulus		0.012	0.2645	0.5514
Echinococcus granulosus	arf GAP with SH3 domain ANK repeat and PH	0.0114	0.2476	0.2439
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Echinococcus multilocularis	cyclin dependent kinase 5	0.0048	0.0656	0.061
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus multilocularis	transfer RNA-Thr	0.0035	0.0278	0.023
Loa Loa (eye worm)	guanylate kinase	0.0114	0.2483	0.3221
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0035	0.0278	0.023
Brugia malayi	hypothetical protein	0.0035	0.0278	0.0303
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0035	0.0278	0.023
Echinococcus granulosus	expressed protein	0.0111	0.2415	0.2377
Schistosoma mansoni	growth factor receptor-bound protein	0.0231	0.5755	0.5734
Brugia malayi	Variant SH3 domain containing protein	0.0111	0.2415	0.3131
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0035	0.0278	0.0303
Entamoeba histolytica	hypothetical protein	0.0111	0.2415	0.6628
Brugia malayi	SH2 domain containing protein	0.012	0.2645	0.3436
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0035	0.0278	0.023
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0037	0.0346	0.3531
Echinococcus multilocularis	mitogen activated protein kinase	0.0057	0.089	0.0845
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0035	0.0278	0.0303
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0297	0.7604	0.7593
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0035	0.0278	0.0303
Entamoeba histolytica	cysteine surface protein, putative	0.0035	0.0278	0.0642
Giardia lamblia	Kinase, STE STE20	0.0082	0.159	1
Loa Loa (eye worm)	AGC/RSK/P70 protein kinase	0.0045	0.0554	0.0669
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Schistosoma mansoni	protein kinase	0.0035	0.0278	0.023
Echinococcus multilocularis	intersectin 2	0.0113	0.2452	0.2415
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Echinococcus multilocularis	protein kinase c epsilon type	0.0031	0.0158	0.0109
Trypanosoma brucei	conserved protein	0.0111	0.2415	1
Echinococcus multilocularis	rac serine:threonine kinase	0.0027	0.005	0.0001
Loa Loa (eye worm)	RhoGAP domain-containing protein	0.0126	0.2826	0.3676
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0035	0.0278	0.0303
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Echinococcus granulosus	src region	0.0111	0.2415	0.2377
Onchocerca volvulus		0.0111	0.2415	0.4978
Onchocerca volvulus		0.0154	0.3618	0.7782
Echinococcus multilocularis	transfer RNA-Ala	0.0111	0.2415	0.2377
Loa Loa (eye worm)	TK/FER protein kinase	0.0154	0.3618	0.4724
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0186	0.4495	0.4467
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0035	0.0278	0.023
Echinococcus granulosus	ephrin type A receptor 4 A	0.0035	0.0278	0.023
Schistosoma mansoni	serine/threonine protein kinase	0.0031	0.0158	0.0109
Schistosoma mansoni	eps8-related protein	0.0111	0.2415	0.2377
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0588	0.0713
Echinococcus granulosus	cyclin dependent kinase 5	0.0048	0.0656	0.061
Schistosoma mansoni	tensin	0.012	0.2645	0.2609
Entamoeba histolytica	protein kinase, putative	0.0111	0.2415	0.6628
Trichomonas vaginalis	CAMK family protein kinase	0.0035	0.0278	0.1152
Echinococcus multilocularis	fch and double sh3 domains protein 2	0.0111	0.2415	0.2377
Loa Loa (eye worm)	TK/FER protein kinase	0.0035	0.0278	0.0303
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0035	0.0278	0.0303
Echinococcus multilocularis	tyrosine protein kinase csk	0.0069	0.123	0.1187
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0035	0.0278	0.0303
Trichomonas vaginalis	STE family protein kinase	0.0035	0.0278	0.1152
Schistosoma mansoni	protein kinase	0.0224	0.5562	0.554
Echinococcus granulosus	fch and double sh3 domains protein 2	0.0111	0.2415	0.2377
Trichomonas vaginalis	conserved hypothetical protein	0.0111	0.2415	1
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Echinococcus granulosus	integrin linked protein kinase	0.0035	0.0278	0.023
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus multilocularis	Protein kinase C, brain isozyme	0.0073	0.1343	0.13
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0035	0.0278	0.1152
Schistosoma mansoni	growth factor receptor-bound protein	0.0231	0.5755	0.5734
Trichomonas vaginalis	conserved hypothetical protein	0.0035	0.0278	0.1152
Brugia malayi	protein-tyrosine kinase	0.0111	0.2415	0.3131
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Onchocerca volvulus		0.012	0.2645	0.5514
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0035	0.0278	0.0642
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Loa Loa (eye worm)	hypothetical protein	0.0231	0.5755	0.7552
Schistosoma mansoni	serine/threonine-protein kinase	0.0027	0.005	0.0001
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.012	0.2645	0.2609
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0035	0.0278	0.0303
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.012	0.2645	0.2609
Schistosoma mansoni	shc transforming protein	0.012	0.2645	0.2609
Schistosoma mansoni	serine/threonine protein kinase	0.0073	0.1343	0.13
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0151	0.3521	0.3489
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0035	0.0278	0.023
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Schistosoma mansoni	hypothetical protein	0.012	0.2645	0.2609
Loa Loa (eye worm)	TK protein kinase	0.0035	0.0278	0.0303
Echinococcus granulosus	tyrosine protein kinase	0.0035	0.0278	0.023
Schistosoma mansoni	tyrosine kinase	0.0263	0.666	0.6644
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0266	0.6728	0.6712
Loa Loa (eye worm)	hypothetical protein	0.0154	0.3618	0.4724
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0154	0.3618	0.3587
Trichomonas vaginalis	CMGC family protein kinase	0.0057	0.089	0.3687
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0672	0.0824
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Entamoeba histolytica	receptor protein kinase, putative	0.0035	0.0278	0.0642
Echinococcus granulosus	protein kinase C gamma type	0.0066	0.1161	0.1118
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0048	0.0656	0.0803
Entamoeba histolytica	hypothetical protein	0.0035	0.0278	0.0642
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0297	0.7604	0.7593
Echinococcus multilocularis	SH2 domain containing protein 7	0.012	0.2645	0.2609
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.012	0.2645	0.2609
Echinococcus granulosus	natriuretic peptide receptor 1	0.0035	0.0278	0.023
Onchocerca volvulus		0.0154	0.3618	0.7782
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Schistosoma mansoni	serine/threonine-protein kinase	0.0027	0.005	0.0001
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Loa Loa (eye worm)	hypothetical protein	0.0111	0.2415	0.3131
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0035	0.0278	0.023
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0037	0.0346	0.125
Echinococcus multilocularis	c src tyrosine kinase	0.03	0.768	0.7669
Loa Loa (eye worm)	TK/CSK protein kinase	0.0069	0.123	0.1563
Echinococcus granulosus	raf serine:threonine protein kinase	0.0041	0.046	0.0413
Echinococcus granulosus	tyrosine kinase	0.0035	0.0278	0.023
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Echinococcus granulosus	nostrin	0.0111	0.2415	0.2377
Loa Loa (eye worm)	TK/FER protein kinase	0.0035	0.0278	0.0303
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Brugia malayi	Tensin	0.012	0.2645	0.3436
Echinococcus multilocularis	activated cdc42 kinase 1	0.0035	0.0278	0.023
Entamoeba histolytica	tyrosin kinase, putative	0.0035	0.0278	0.0642
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Trypanosoma brucei	protein kinase, putative	0.0057	0.089	0.3556
Schistosoma mansoni	suppressor of cytokine signaling	0.012	0.2645	0.2609
Loa Loa (eye worm)	TK/FER protein kinase	0.0035	0.0278	0.0303
Schistosoma mansoni	protein kinase	0.0035	0.0278	0.023
Echinococcus granulosus	dual specificity mitogen activated protein	0.0082	0.159	0.1549
Schistosoma mansoni	SH2A	0.012	0.2645	0.2609
Echinococcus granulosus	suppressor of cytokine signaling 6	0.012	0.2645	0.2609
Schistosoma mansoni	ephrin receptor	0.0035	0.0278	0.023
Giardia lamblia	Kinase, CMGC CDK	0.0048	0.0656	0.2877
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0035	0.0278	0.023
Echinococcus granulosus	tyrosine protein kinase HCK	0.0066	0.1155	0.1111
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0035	0.0278	0.0303
Trichomonas vaginalis	CMGC family protein kinase	0.0048	0.0656	0.2715
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.012	0.2645	0.2609
Echinococcus multilocularis	protein kinase	0.0035	0.0278	0.023
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Brugia malayi	Receptor family ligand binding region containing protein	0.0035	0.0278	0.0303
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus multilocularis	cyclin dependent kinase 1	0.0048	0.0656	0.061
Brugia malayi	integrin-linked kinase	0.0035	0.0278	0.0303
Entamoeba histolytica	protein kinase, putative	0.0047	0.0616	0.1589
Schistosoma mansoni	serine/threonine protein kinase	0.0048	0.0656	0.061
Trypanosoma brucei	mitogen activated protein kinase 4, putative	0.0057	0.089	0.3556
Schistosoma mansoni	GTPase activating protein	0.012	0.2645	0.2609
Loa Loa (eye worm)	CMGC/CDK/CDK5 protein kinase	0.0048	0.0656	0.0803
Echinococcus granulosus	protein kinase	0.0035	0.0278	0.023
Schistosoma mansoni	vav2	0.0128	0.2888	0.2853
Echinococcus multilocularis	NCK adaptor protein	0.0231	0.5755	0.5734
Trypanosoma cruzi	mitogen activated protein kinase 4, putative	0.0057	0.089	0.3552
Loa Loa (eye worm)	TK/FER protein kinase	0.0154	0.3618	0.4724
Echinococcus multilocularis		0.012	0.2645	0.2609
Schistosoma mansoni	cell polarity protein	0.0111	0.2415	0.2377
Echinococcus multilocularis	RNA directed DNA polymerase	0.0042	0.049	0.0443
Echinococcus granulosus	rho guanine nucleotide exchange factor 7	0.0111	0.2415	0.2377
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Brugia malayi	hypothetical protein	0.012	0.2645	0.3436
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Brugia malayi	protein kinase C II.	0.0031	0.0158	0.0144
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0154	0.3618	1
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Onchocerca volvulus		0.0154	0.3618	0.7782
Echinococcus granulosus	phosphatidylinositol 3 kinase regulatory subunit	0.012	0.2645	0.2609
Trichomonas vaginalis	conserved hypothetical protein	0.0111	0.2415	1
Schistosoma mansoni	serine/threonine protein kinase	0.0041	0.046	0.0413
Schistosoma mansoni	hypothetical protein	0.0035	0.0278	0.023
Onchocerca volvulus		0.0154	0.3618	0.7782
Entamoeba histolytica	hypothetical protein	0.0111	0.2415	0.6628
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0035	0.0278	0.3777
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0035	0.0278	0.0303
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0057	0.089	0.3552
Loa Loa (eye worm)	TK protein kinase	0.0035	0.0278	0.0303
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0122	0.2713	0.7463
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0037	0.0346	0.1256
Loa Loa (eye worm)	TK/FER protein kinase	0.0154	0.3618	0.4724
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Echinococcus granulosus	tyrosine protein kinase csk	0.0069	0.123	0.1187
Echinococcus multilocularis	epidermal growth factor receptor	0.0035	0.0278	0.023
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0035	0.0278	0.023
Entamoeba histolytica	hypothetical protein	0.0111	0.2415	0.6628
Brugia malayi	Variant SH3 domain containing protein	0.0111	0.2415	0.3131
Echinococcus multilocularis	protein kinase	0.0035	0.0278	0.023
Echinococcus multilocularis	expressed protein	0.0111	0.2415	0.2377
Schistosoma mansoni	atypical protein kinase C	0.0029	0.012	0.0071
Trypanosoma cruzi	protein kinase, putative	0.0035	0.0278	0.0963
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Brugia malayi	cytokine inducible SH2-containing protein 5	0.012	0.2645	0.3436
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0035	0.0278	0.023
Trichomonas vaginalis	CAMK family protein kinase	0.0027	0.0049	0.0203
Loa Loa (eye worm)	TK/FER protein kinase	0.0154	0.3618	0.4724
Leishmania major	protein kinase, putative	0.0037	0.0346	0.1256
Loa Loa (eye worm)	TK/ABL protein kinase	0.0154	0.3618	0.4724
Echinococcus granulosus	Protein kinase C brain isozyme	0.0073	0.1343	0.13
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0035	0.0278	0.023
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0035	0.0278	0.023
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Onchocerca volvulus	Suppressor of cytokine signaling at 36E homolog	0.012	0.2645	0.5514
Loa Loa (eye worm)	TK/FAK protein kinase	0.0035	0.0278	0.0303
Brugia malayi	Protein kinase domain containing protein	0.0154	0.3618	0.4724
Echinococcus multilocularis	guanine nucleotide exchange factor VAV2	0.0126	0.2826	0.2791
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0035	0.0278	0.023
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0297	0.7604	0.7593
Leishmania major	cell division related protein kinase 2,cdc2-related kinase	0.0048	0.0656	0.2564
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0278	0.0303
Entamoeba histolytica	receptor protein kinase, putative	0.0035	0.0278	0.0642
Plasmodium falciparum	protein kinase, putative	0.0035	0.0278	0.3777
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0035	0.0278	0.0303
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Trypanosoma cruzi	cdc2-related kinase 1	0.0048	0.0656	0.256
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Echinococcus multilocularis	suppressor of cytokine signaling 6	0.012	0.2645	0.2609
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0231	0.5755	0.7552
Echinococcus granulosus	cyclin dependent kinase	0.0048	0.0656	0.061
Brugia malayi	SH2 domain containing protein	0.0154	0.3618	0.4724
Schistosoma mansoni	tensin-related	0.012	0.2645	0.2609
Trypanosoma brucei	Pseudokinase, putative	0.0035	0.0278	0.0969
Loa Loa (eye worm)	TK/FER protein kinase	0.0035	0.0278	0.0303
Echinococcus granulosus	tyrosine protein kinase csk	0.0069	0.123	0.1187
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0035	0.0278	0.023
Brugia malayi	SH2 domain containing protein	0.012	0.2645	0.3436
Entamoeba histolytica	BAR/SH3 domain containing protein	0.0111	0.2415	0.6628
Trypanosoma cruzi	paraflagellar rod protein 5, putative	0.0111	0.2415	1
Trichomonas vaginalis	AGC family protein kinase	0.0047	0.0616	0.2551
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0297	0.7604	0.7593
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Loa Loa (eye worm)	CMGC/MAPK/ERK1 protein kinase	0.0057	0.089	0.1113
Loa Loa (eye worm)	protein-tyrosine kinase	0.0111	0.2415	0.3131
Echinococcus granulosus	suppressor of cytokine signaling 7	0.012	0.2645	0.2609
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Onchocerca volvulus		0.012	0.2645	0.5514
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0035	0.0278	0.023
Brugia malayi	Variant SH3 domain containing protein	0.0123	0.2744	0.3567
Onchocerca volvulus		0.0111	0.2415	0.4978
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Schistosoma mansoni	slit-robo rho gtpase activating protein	0.0111	0.2415	0.2377
Brugia malayi	Variant SH3 domain containing protein	0.0111	0.2415	0.3131
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0297	0.7604	0.7593
Leishmania major	hypothetical protein, conserved	0.0035	0.0278	0.0969
Entamoeba histolytica	protein kinase, putative	0.0122	0.2713	0.7463
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.012	0.2645	0.3436
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0027	0.005	0.0004
Schistosoma mansoni	serine/threonine protein kinase	0.0035	0.0278	0.023
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Echinococcus multilocularis	SH2 domain containing adapter protein F	0.012	0.2645	0.2609
Giardia lamblia	Kinase, CMGC CDK	0.0048	0.0656	0.2877
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Brugia malayi	protein-tyrosine kinase	0.0186	0.4495	0.5884
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0035	0.0278	0.023
Loa Loa (eye worm)	TK/FER protein kinase	0.0154	0.3618	0.4724
Echinococcus granulosus	insulin receptor	0.0035	0.0278	0.023
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Leishmania major	hypothetical protein, conserved	0.0111	0.2415	1
Schistosoma mansoni	protein kinase	0.0037	0.0346	0.0298
Trypanosoma cruzi	protein kinase, putative	0.0035	0.0278	0.0963
Brugia malayi	cell division control protein 2 homolog	0.0048	0.0656	0.0803
Loa Loa (eye worm)	TK/ROR protein kinase	0.0035	0.0278	0.0303
Entamoeba histolytica	hypothetical protein	0.0035	0.0278	0.0642
Loa Loa (eye worm)	AGC/PKC/ETA protein kinase	0.0031	0.0158	0.0144
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Schistosoma mansoni	tyrosine protein kinase	0.0035	0.0278	0.023
Schistosoma mansoni	tyrosine kinase	0.0154	0.3618	0.3587
Schistosoma mansoni	serine/threonine RGC	0.0035	0.0278	0.023
Entamoeba histolytica	hypothetical protein	0.0035	0.0278	0.0642
Trichomonas vaginalis	TK family protein kinase	0.0035	0.0278	0.1152
Loa Loa (eye worm)	TK protein kinase	0.0035	0.0278	0.0303
Entamoeba histolytica	serine/threonine kinase, putative	0.0035	0.0278	0.0642
Loa Loa (eye worm)	hypothetical protein	0.0111	0.2415	0.3131
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0035	0.0278	0.0969
Loa Loa (eye worm)	TK/FER protein kinase	0.0035	0.0278	0.0303
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0035	0.0278	0.0303
Echinococcus multilocularis	integrin linked protein kinase	0.0035	0.0278	0.023
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Schistosoma mansoni	protein kinase	0.0035	0.0278	0.023
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Loa Loa (eye worm)	hypothetical protein	0.0111	0.2415	0.3131
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Trichomonas vaginalis	protein kinase atn1, putative	0.0035	0.0278	0.1152
Echinococcus granulosus	5'partial\|cyclin dependent kinase 1	0.0048	0.0656	0.061
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0035	0.0278	0.023
Echinococcus granulosus	NCK adaptor protein	0.0231	0.5755	0.5734
Loa Loa (eye worm)	TK/ALK protein kinase	0.0035	0.0278	0.0303
Onchocerca volvulus	Suppressor of cytokine signaling 7 homolog	0.012	0.2645	0.5514
Entamoeba histolytica	hypothetical protein	0.0111	0.2415	0.6628
Schistosoma mansoni	apoptosis stimulating of P53	0.0111	0.2415	0.2377
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0278	0.0303
Toxoplasma gondii	protein kinase	0.0035	0.0278	0.2724
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0278	0.0303
Brugia malayi	MAP kinase sur-1	0.0057	0.089	0.1113
Brugia malayi	SH2 domain containing protein	0.012	0.2645	0.3436
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0035	0.0278	0.0303
Loa Loa (eye worm)	hypothetical protein	0.0111	0.2415	0.3131
Entamoeba histolytica	protein kinase domain containing protein	0.0037	0.0346	0.0832
Loa Loa (eye worm)	TK protein kinase	0.0035	0.0278	0.0303
Entamoeba histolytica	hypothetical protein	0.0111	0.2415	0.6628
Brugia malayi	Furin-like cysteine rich region family protein	0.0035	0.0278	0.0303
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0035	0.0278	0.0303
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0035	0.0278	0.023
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Loa Loa (eye worm)	TK/Met protein kinase	0.0035	0.0278	0.0303
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Schistosoma mansoni	run and tbc1 domain containing	0.0111	0.2415	0.2377
Loa Loa (eye worm)	TK/FER protein kinase	0.0154	0.3618	0.4724
Echinococcus granulosus	epidermal growth factor receptor	0.0035	0.0278	0.023
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0037	0.0346	0.125
Entamoeba histolytica	tyrosin kinase, putative	0.0035	0.0278	0.0642
Trypanosoma cruzi	cdc2-related kinase 1	0.0048	0.0656	0.256
Echinococcus granulosus	serine/threonine protein kinase	0.0027	0.005	0.0001
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Schistosoma mansoni	protein kinase	0.0035	0.0278	0.023
Entamoeba histolytica	hypothetical protein, conserved	0.0111	0.2415	0.6628
Brugia malayi	Variant SH3 domain containing protein	0.0231	0.5755	0.7552
Leishmania major	protein kinase, putative	0.0035	0.0278	0.0969
Trichomonas vaginalis	p67phox protein, putative	0.0111	0.2415	1
Echinococcus multilocularis	mitogen activated protein kinase 3	0.0057	0.089	0.0845
Brugia malayi	SH2 domain containing protein	0.012	0.2645	0.3436
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Entamoeba histolytica	serine/threonine kinase, putative	0.0035	0.0278	0.0642
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0278	0.0303
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase abl1	0.0231	0.5755	0.5734
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Schistosoma mansoni	suppressor of cytokine signaling	0.012	0.2645	0.2609
Schistosoma mansoni	hypothetical protein	0.0111	0.2415	0.2377
Trichomonas vaginalis	AGC family protein kinase	0.0047	0.0616	0.2551
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Entamoeba histolytica	serine/threonine kinase, putative	0.0035	0.0278	0.0642
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0297	0.7604	0.7593
Loa Loa (eye worm)	SH2 domain-containing protein	0.0154	0.3597	0.4696
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Echinococcus granulosus	c src tyrosine kinase	0.03	0.768	0.7669
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Brugia malayi	Raf kinase	0.0035	0.0278	0.0303
Entamoeba histolytica	serine/threonine kinase, putative	0.0035	0.0278	0.0642
Entamoeba histolytica	protein kinase, putative	0.0028	0.0087	0.0106
Trypanosoma brucei	rac serine-threonine kinase, putative	0.0047	0.0616	0.2397
Echinococcus granulosus	slit robo rho gtpase activating protein 1	0.0111	0.2415	0.2377
Loa Loa (eye worm)	STAT protein	0.012	0.2645	0.3436
Trichomonas vaginalis	AGC family protein kinase	0.0047	0.0616	0.2551
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0035	0.0278	0.023
Schistosoma mansoni	protein kinase	0.0224	0.5562	0.554
Schistosoma mansoni	formin binding protein and related proteins	0.0111	0.2415	0.2377
Loa Loa (eye worm)	hypothetical protein	0.0042	0.049	0.0584
Loa Loa (eye worm)	TK/FER protein kinase	0.0035	0.0278	0.0303
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus multilocularis	serine threonine protein kinase	0.0066	0.1161	0.1118
Trypanosoma brucei	protein kinase, putative	0.0037	0.0346	0.1256
Brugia malayi	SH2 domain containing protein	0.012	0.2645	0.3436
Echinococcus granulosus	tyrosine protein kinase csk	0.0069	0.123	0.1187
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Echinococcus granulosus	tyrosine protein kinase Lyn	0.03	0.7672	0.7661
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0035	0.0278	0.0303
Echinococcus multilocularis	SHC transforming protein 3	0.012	0.2645	0.2609
Schistosoma mansoni	tyrosine kinase	0.0383	1	1
Trichomonas vaginalis	conserved hypothetical protein	0.0035	0.0278	0.1152
Loa Loa (eye worm)	TK/FER protein kinase	0.0154	0.3618	0.4724
Loa Loa (eye worm)	hypothetical protein	0.012	0.2645	0.3436
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0154	0.3618	0.3587
Plasmodium falciparum	protein kinase 5	0.0048	0.0656	1
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0035	0.0278	0.023
Trichomonas vaginalis	conserved hypothetical protein	0.0111	0.2415	1
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0035	0.0278	0.023
Loa Loa (eye worm)	TK/RYK protein kinase	0.0035	0.0278	0.0303
Entamoeba histolytica	hypothetical protein	0.0035	0.0278	0.0642
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Entamoeba histolytica	hypothetical protein	0.0035	0.0278	0.0642
Brugia malayi	Protein kinase c protein 2	0.0053	0.0777	0.0964
Plasmodium falciparum	protein kinase, putative	0.0035	0.0278	0.3777
Schistosoma mansoni	protein kinase	0.0035	0.0278	0.023
Echinococcus granulosus	protein kinase c iota type	0.0029	0.012	0.0071
Schistosoma mansoni	tyrosine kinase	0.0035	0.0278	0.023
Leishmania major	mitogen activated protein kinase, putative,map kinase, putative	0.0057	0.089	0.3556
Plasmodium falciparum	protein kinase, putative	0.0037	0.0346	0.4896
Entamoeba histolytica	protein kinase, putative	0.0035	0.0278	0.0642
Echinococcus granulosus	protein tyrosine kinase	0.0035	0.0278	0.023
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0035	0.0278	0.1152
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Loa Loa (eye worm)	TK protein kinase	0.0066	0.1155	0.1463
Loa Loa (eye worm)	TK/FER protein kinase	0.0035	0.0278	0.0303
Echinococcus multilocularis	SH2 motif	0.012	0.2645	0.2609
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0035	0.0278	0.023
Trichomonas vaginalis	AGC family protein kinase	0.0047	0.0616	0.2551
Giardia lamblia	Kinase, CMGC MAPK	0.0057	0.089	0.4666
Trichomonas vaginalis	TKL family protein kinase	0.0035	0.0278	0.1152
Brugia malayi	Variant SH3 domain containing protein	0.0126	0.2826	0.3676
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0035	0.0278	0.023
Echinococcus multilocularis	tensin	0.012	0.2645	0.2609
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0297	0.7604	0.7593
Entamoeba histolytica	BAR/SH3 domain containing protein	0.0111	0.2415	0.6628
Entamoeba histolytica	hypothetical protein, conserved	0.0111	0.2415	0.6628
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0035	0.0278	0.0303
Brugia malayi	Variant SH3 domain containing protein	0.0111	0.2415	0.3131
Brugia malayi	Dual specificity mitogen-activated protein kinase kinase mek-2	0.0082	0.159	0.204
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0126	0.2826	0.2791
Entamoeba histolytica	cell division protein kinase 2, putative	0.0048	0.0656	0.17
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0035	0.0278	0.2724
Echinococcus multilocularis	tyrosine protein kinase csk	0.0069	0.123	0.1187
Echinococcus multilocularis	N chimaerin	0.0126	0.2826	0.2791
Brugia malayi	Protein kinase domain containing protein	0.0035	0.0278	0.0303
Echinococcus multilocularis	growth factor receptor bound protein 2	0.0231	0.5755	0.5734
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0297	0.7604	0.7593
Entamoeba histolytica	protein kinase domain containing protein	0.0035	0.0278	0.0642
Echinococcus multilocularis	telomerase reverse transcriptase subunit	0.0042	0.049	0.0443
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0035	0.0278	0.0642
Echinococcus multilocularis	cyclin dependent kinase 1	0.0048	0.0656	0.061
Trichomonas vaginalis	CMGC family protein kinase	0.0048	0.0656	0.2715
Entamoeba histolytica	ankyrin repeat protein	0.0035	0.0278	0.0642
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0266	0.6728	0.6712
Entamoeba histolytica	tyrosine kinase, putative	0.0035	0.0278	0.0642
Echinococcus granulosus	RNA directed DNA polymerase	0.0042	0.049	0.0443

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 149 nM	Inhibition of LIMK1 (unknown origin) assessed as remaining ATP level using cofilin-2 protein as substrate measured after 60 mins incubation with enzyme by KinaseGlo assay	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3347688

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 925035