TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 412.871 | Formula: C18H22ClN2O3PS
H donors: 1 H acceptors: 2 LogP: 3.94 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: CCOP(=O)(Cc1ccc(cc1)c1nc2c(s1)cc(cc2)N)OCC.Cl
InChi: 1S/C18H21N2O3PS.ClH/c1-3-22-24(21,23-4-2)12-13-5-7-14(8-6-13)18-20-16-10-9-15(19)11-17(16)25-18;/h5-11H,3-4,12,19H2,1-2H3;1H
InChiKey: ZVHNFRRRSUJWSW-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Plasmodium falciparum	hexose transporter	0.0051	0.0312	1
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	expression site-associated gene 4 (ESAG4) protein, putative	0.0029	0.0129	0.5709
Echinococcus multilocularis	beta LACTamase domain containing family member	0.004	0.0221	0.0389
Loa Loa (eye worm)	D-ets-4 DNA binding domain-containing protein	0.0081	0.0547	0.0547
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.004	0.0221	1
Schistosoma mansoni	gabp alpha	0.0081	0.0547	0.0954
Leishmania major	receptor-type adenylate cyclase b	0.0029	0.0129	0.5709
Trichomonas vaginalis	penicillin-binding protein, putative	0.004	0.0221	0.7015
Mycobacterium ulcerans	hypothetical protein	0.0029	0.0129	0.5709
Schistosoma mansoni	protein tyrosine kinase	0.0029	0.0129	0.0216
Trichomonas vaginalis	conserved hypothetical protein	0.0051	0.0312	1
Plasmodium falciparum	guanylyl cyclase	0.003	0.0143	0.447
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Schistosoma mansoni	sodium/potassium-dependent atpase beta subunit	0.0069	0.0452	0.0785
Schistosoma mansoni	lamin	0.0026	0.0109	0.0181
Mycobacterium ulcerans	adenylate or guanylate cyclase	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Brugia malayi	Receptor family ligand binding region containing protein	0.0029	0.0129	0.0231
Toxoplasma gondii	adenylate and guanylate cyclase catalytic domain-containing protein	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Echinococcus granulosus	nervana 2	0.0069	0.0452	0.0796
Schistosoma mansoni	soluble guanylate cyclase gcy	0.0029	0.0129	0.0216
Toxoplasma gondii	guanylyl cyclase	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Onchocerca volvulus	Adenylate cyclase type 2 homolog	0.0674	0.5318	1
Trypanosoma brucei	adenylyl cyclase	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0183	0.0183
Schistosoma mansoni	protein kinase	0.0029	0.0129	0.0216
Echinococcus granulosus	Na:K ATPase alpha subunit	0.0035	0.0183	0.0322
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	expression site-associated gene 4 (ESAG4) protein, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0674	0.5318	0.5318
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0029	0.0129	0.0231
Echinococcus granulosus	calcium transporting ATPase type 2C member	0.0013	0.0006	0.0011
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0029	0.0129	0.0038
Onchocerca volvulus		0.0674	0.5318	1
Schistosoma mansoni	soluble guanylate cyclase gcy	0.0029	0.0129	0.0216
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	Adenylate and Guanylate cyclase catalytic domain containing protein, putative	0.0029	0.0129	0.5709
Loa Loa (eye worm)	hypothetical protein	0.0069	0.0453	0.0453
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.004	0.0221	0.0503
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0051	0.0312	0.055
Treponema pallidum	adenylate cyclase	0.0029	0.0129	0.5
Leishmania major	receptor-type adenylate cyclase a	0.0029	0.0129	0.5709
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0029	0.0129	0.0227
Loa Loa (eye worm)	hypothetical protein	0.0069	0.0452	0.0452
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Schistosoma mansoni	serine/threonine RGC	0.0029	0.0129	0.0216
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0129	0.0129
Trypanosoma cruzi	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Schistosoma mansoni	sodium / potassium ATPase beta chain	0.0069	0.0452	0.0785
Trypanosoma brucei	expression site-associated gene 4 (ESAG4) protein, putative	0.0029	0.0129	0.5709
Toxoplasma gondii	facilitative glucose transporter GT1	0.0051	0.0312	1
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, frameshift	0.0029	0.0129	0.5709
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Brugia malayi	Sugar transporter family protein	0.0051	0.0312	0.0576
Trichomonas vaginalis	guanylate cyclase beta 1 subunit, putative	0.0029	0.0129	0.4005
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0029	0.0129	0.0227
Schistosoma mansoni	adenylate cyclase	0.0029	0.0129	0.0216
Echinococcus multilocularis	lamin	0.0026	0.0109	0.0192
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0129	0.0129
Echinococcus multilocularis	Tetracycline resistance leader peptide, TetL	0.0013	0.0006	0.0011
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0051	0.0312	0.055
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	expression site-associated gene 4 (ESAG4) protein, putative	0.0029	0.0129	0.5709
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0029	0.0129	0.0227
Trypanosoma brucei	adenylyl cyclase, frameshift	0.0029	0.0129	0.5709
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Toxoplasma gondii	ABC1 family protein	0.004	0.0221	0.7015
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Brugia malayi	Intermediate filament tail domain containing protein	0.0026	0.0109	0.0193
Trichomonas vaginalis	adenylate cyclase, type VII, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	expression site associated gene (ESAG) 4 protein, putative	0.0029	0.0129	0.5709
Mycobacterium ulcerans	LuxR family transcriptional regulator	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate cyclase type III, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate cyclase type IX, putative	0.0029	0.0129	0.4005
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0044	0.0256	0.045
Mycobacterium ulcerans	adenylate cyclase	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Schistosoma mansoni	ets-related	0.0245	0.1868	0.3283
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Schistosoma mansoni	sodium/potassium-dependent atpase beta subunit	0.0069	0.0452	0.0785
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0044	0.0256	0.045
Leishmania major	receptor-type adenylate cyclase b	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Echinococcus multilocularis	nervana 2	0.0069	0.0452	0.0796
Echinococcus granulosus	adenylate cyclase 9	0.0029	0.0129	0.0227
Echinococcus multilocularis	solute carrier family 2, facilitated glucose	0.0051	0.0312	0.055
Schistosoma mansoni	soluble guanylate cyclase gcy	0.0029	0.0129	0.0216
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	conserved hypothetical protein	0.0029	0.0129	0.4005
Loa Loa (eye worm)	sodium/potassium-transporting ATPase subunit alpha	0.0031	0.0144	0.0144
Brugia malayi	Guanylyl cyclase protein 23	0.0029	0.0129	0.0231
Trichomonas vaginalis	soluble guanylate cyclase gcy, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	adenylyl cyclase	0.0029	0.0129	0.5709
Mycobacterium ulcerans	adenylate cyclase	0.0029	0.0129	0.5709
Echinococcus multilocularis	adenylate cyclase	0.0029	0.0129	0.0227
Trypanosoma cruzi	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Giardia lamblia	Potassium-transporting ATPase alpha chain 1	0.0035	0.0183	1
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Mycobacterium tuberculosis	Probable lipase LipE	0.004	0.0221	0.0503
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0029	0.0129	0.0231
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0029	0.0129	0.0129
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Brugia malayi	intermediate filament protein	0.0026	0.0109	0.0193
Mycobacterium tuberculosis	Conserved protein	0.004	0.0221	0.0503
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate cyclase type IX, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Echinococcus granulosus	adenylate cyclase	0.0029	0.0129	0.0227
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0089	0.0089
Trypanosoma brucei	expression site-associated gene 4 (ESAG4) protein, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	procyclic-enriched flagellar receptor adenylate cyclase 6	0.0029	0.0129	0.5709
Schistosoma mansoni	soluble guanylate cyclase gcy	0.0029	0.0129	0.0216
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Brugia malayi	beta-lactamase family protein	0.004	0.0221	0.0404
Schistosoma mansoni	adenylate cyclase	0.0029	0.0129	0.0216
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.0256	0.0439
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0044	0.0256	0.045
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Schistosoma mansoni	glucose transport protein	0.0051	0.0312	0.0539
Loa Loa (eye worm)	hypothetical protein	0.0069	0.0452	0.0452
Loa Loa (eye worm)	hypothetical protein	0.0645	0.5087	0.5087
Trichomonas vaginalis	guanylate cyclase beta 2 subunit, putative	0.0029	0.0129	0.4005
Onchocerca volvulus		0.004	0.0221	0.0215
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0075	0.0075
Echinococcus granulosus	beta LACTamase domain containing family member	0.004	0.0221	0.0389
Echinococcus granulosus	GA binding protein alpha chain	0.0081	0.0547	0.0964
Trichomonas vaginalis	D-aminoacylase, putative	0.004	0.0221	0.7015
Trypanosoma cruzi	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0029	0.0129	0.0227
Mycobacterium tuberculosis	Conserved protein	0.004	0.0221	0.0503
Echinococcus multilocularis	sodium:potassium dependent atpase beta subunit	0.0069	0.0452	0.0796
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0044	0.0256	0.0256
Trichomonas vaginalis	penicillin-binding protein, putative	0.004	0.0221	0.7015
Trichomonas vaginalis	adenylate cyclase type IX, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	procyclic-enriched flagellar receptor adenylate cyclase 5	0.0029	0.0129	0.5709
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0029	0.0129	0.0231
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Trypanosoma cruzi	hypothetical protein, conserved	0.004	0.0221	1
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	adenylyl cyclase	0.0029	0.0129	0.5709
Mycobacterium ulcerans	adenylylate/guanylate cyclase	0.0029	0.0129	0.5709
Trichomonas vaginalis	esterase, putative	0.004	0.0221	0.7015
Echinococcus granulosus	plasma membrane calcium transporting ATPase	0.0013	0.0006	0.0011
Brugia malayi	hypothetical protein	0.0029	0.0129	0.0231
Echinococcus granulosus	nervana 2	0.0069	0.0452	0.0796
Loa Loa (eye worm)	hypothetical protein	0.004	0.0221	0.0221
Trypanosoma brucei	procyclic-enriched flagellar receptor adenylate cyclase 2	0.0029	0.0129	0.5709
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Loa Loa (eye worm)	hypothetical protein	0.004	0.0221	0.0221
Brugia malayi	adenylate cyclase, type IX	0.0029	0.0129	0.0231
Schistosoma mansoni	glucose transport protein	0.0051	0.0312	0.0539
Mycobacterium tuberculosis	Conserved protein	0.004	0.0221	0.0503
Schistosoma mansoni	lamin	0.0026	0.0109	0.0181
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Plasmodium vivax	guanylyl cyclase, putative	0.0029	0.0129	0.4005
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0029	0.0129	0.0227
Trichomonas vaginalis	atrial natriuretic peptide receptor, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	soluble guanylate cyclase gcy, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma cruzi	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	hypothetical protein	0.0029	0.0129	0.4005
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	conserved hypothetical protein	0.0029	0.0129	0.4005
Loa Loa (eye worm)	sugar transporter	0.0051	0.0312	0.0312
Trichomonas vaginalis	adenylate cyclase type, putative	0.0029	0.0129	0.4005
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0051	0.0312	0.055
Mycobacterium ulcerans	esterase/lipase LipP	0.004	0.0221	1
Trypanosoma cruzi	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Loa Loa (eye worm)	hypothetical protein	0.004	0.0221	0.0221
Trypanosoma brucei	adenylyl cyclase	0.0029	0.0129	0.5709
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylyl cyclase type V, putative	0.0029	0.0129	0.4005
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.004	0.0221	0.0221
Trichomonas vaginalis	adenylate cyclase type, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	expression site-associated gene 4 (ESAG4) protein, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Schistosoma mansoni	soluble guanylate cyclase gcy	0.0029	0.0129	0.0216
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Echinococcus multilocularis	nervana 2	0.0069	0.0452	0.0796
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Schistosoma mansoni	transmemberane protein	0.0069	0.0452	0.0785
Schistosoma mansoni	hypothetical protein	0.0029	0.0129	0.0216
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Plasmodium falciparum	adenylyl cyclase alpha	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Echinococcus multilocularis	adenylate cyclase 9	0.0029	0.0129	0.0227
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0026	0.0109	0.0109
Trichomonas vaginalis	retinal guanylate cyclase, putative	0.0029	0.0129	0.4005
Schistosoma mansoni	intermediate filament proteins	0.0026	0.0109	0.0181
Trichomonas vaginalis	guanylate cyclase beta 2 subunit, putative	0.0029	0.0129	0.4005
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.004	0.0221	0.0503
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0129	0.0129
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Mycobacterium leprae	conserved hypothetical protein	0.004	0.0221	1
Schistosoma mansoni	hypothetical protein	0.0029	0.0129	0.0216
Plasmodium falciparum	adenylyl cyclase beta	0.0029	0.0129	0.4005
Onchocerca volvulus	Adenylate cyclase type 3 homolog	0.0674	0.5318	1
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Mycobacterium ulcerans	hypothetical protein	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0029	0.0129	0.0129
Toxoplasma gondii	adenylate and guanylate cyclase catalytic domain-containing protein	0.0029	0.0129	0.4005
Echinococcus multilocularis	adenylate cyclase type IX	0.0611	0.4811	0.8475
Plasmodium vivax	Adenylate and Guanylate cyclase catalytic domain containing protein	0.003	0.0143	0.447
Schistosoma mansoni	na+/k+ atpase alpha subunit	0.0035	0.0183	0.0311
Schistosoma mansoni	hypothetical protein	0.0029	0.0129	0.0216
Echinococcus granulosus	plasma membrane calcium transporting ATPase 2	0.0013	0.0006	0.0011
Trypanosoma brucei	adenylyl cyclase	0.0029	0.0129	0.5709
Loa Loa (eye worm)	guanylyl cyclase/natriuretic peptide receptor	0.0029	0.0129	0.0129
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	expression site-associated gene 4 (ESAG4) protein, putative	0.0029	0.0129	0.5709
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	soluble guanylate cyclase gcy, putative	0.0029	0.0129	0.4005
Trypanosoma cruzi	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Mycobacterium ulcerans	lipase LipD	0.004	0.0221	1
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Mycobacterium ulcerans	adenylate cyclase CyaA	0.0029	0.0129	0.5709
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.004	0.0221	0.0378
Echinococcus granulosus	sodium:potassium dependent atpase beta subunit	0.0069	0.0452	0.0796
Brugia malayi	Adenylyl cyclase protein	0.0674	0.5318	1
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Schistosoma mansoni	adenylate cyclase	0.0029	0.0129	0.0216
Trypanosoma cruzi	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Onchocerca volvulus		0.0034	0.0173	0.0123
Trypanosoma cruzi	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Echinococcus multilocularis	sodium:potassium dependent atpase beta subunit	0.0069	0.0452	0.0796
Mycobacterium ulcerans	lignin peroxidase LipJ	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate cyclase type VI, putative	0.0029	0.0129	0.4005
Schistosoma mansoni	microtubule-associated protein tau	0.0719	0.5677	1
Echinococcus granulosus	nervana 2	0.0069	0.0452	0.0796
Trichomonas vaginalis	adenylate cyclase, type VII, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	conserved hypothetical protein	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate cyclase type IX, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	hypothetical protein, conserved	0.004	0.0221	1
Trichomonas vaginalis	retinal guanylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	intestinal guanylate cyclase, putative	0.0029	0.0129	0.4005
Schistosoma mansoni	Na+/K+ transporting ATPase subunit alpha	0.0035	0.0183	0.0311
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.0256	0.0439
Echinococcus multilocularis	plasma membrane calcium transporting ATPase	0.0013	0.0006	0.0011
Trichomonas vaginalis	conserved hypothetical protein	0.0029	0.0129	0.4005
Echinococcus multilocularis	nervana 2	0.0069	0.0452	0.0796
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0129	0.0129
Mycobacterium tuberculosis	Probable hydrolase	0.004	0.0221	0.0503
Leishmania major	receptor-type adenylate cyclase b	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Entamoeba histolytica	calcium-transporting P-type ATPase, putative	0.0013	0.0006	0.5
Echinococcus multilocularis	Na+:K+ ATPase alpha subunit	0.0035	0.0183	0.0322
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0129	0.0129
Brugia malayi	Ets-domain containing protein	0.0081	0.0547	0.1018
Leishmania major	hypothetical protein, conserved	0.004	0.0221	1
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Mycobacterium ulcerans	metal cation transporter p-type ATPase a	0.0034	0.0173	0.7758
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0029	0.0129	0.0227
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0129	0.0129
Trichomonas vaginalis	conserved hypothetical protein	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Onchocerca volvulus		0.0029	0.0129	0.0038
Trypanosoma cruzi	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Schistosoma mansoni	receptor-type adenylate cyclase	0.0029	0.0129	0.0216
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate cyclase type VI, putative	0.0029	0.0129	0.4005
Onchocerca volvulus		0.004	0.0221	0.0215
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0029	0.0129	0.0227
Echinococcus multilocularis	adenylate cyclase 9	0.0674	0.5318	0.9367
Loa Loa (eye worm)	fli-1 protein	0.0245	0.1868	0.1868
Plasmodium vivax	hypothetical protein, conserved	0.004	0.0221	0.7015
Brugia malayi	beta-lactamase family protein	0.004	0.0221	0.0404
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.0256	0.0439
Trichomonas vaginalis	adenylate cyclase type III, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	conserved hypothetical protein	0.0029	0.0129	0.4005
Trichomonas vaginalis	atrial natriuretic peptide receptor, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	D-aminoacylase, putative	0.004	0.0221	0.7015
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0029	0.0129	0.0129
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0029	0.0129	0.5709
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0129	0.0129
Onchocerca volvulus		0.0069	0.0452	0.0658
Brugia malayi	Na,K-ATPase alpha subunit	0.0035	0.0183	0.0332
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate cyclase type III, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Mycobacterium ulcerans	hypothetical protein	0.004	0.0221	1
Echinococcus multilocularis	GA binding protein alpha chain	0.0081	0.0547	0.0964
Echinococcus multilocularis	sodium:potassium dependent atpase beta subunit	0.0069	0.0452	0.0796
Schistosoma mansoni	soluble guanylate cyclase gcy	0.0029	0.0129	0.0216
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Echinococcus multilocularis	musashi	0.0026	0.0109	0.0192
Trichomonas vaginalis	adenylate cyclase type vIII, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	conserved hypothetical protein	0.0029	0.0129	0.4005
Mycobacterium tuberculosis	Probable esterase LipL	0.004	0.0221	0.0503
Mycobacterium ulcerans	hypothetical protein	0.0029	0.0129	0.5709
Echinococcus multilocularis	Ca2+ transporting ATPase plasma membrane	0.0013	0.0006	0.0011
Brugia malayi	cytoplasmic intermediate filament protein	0.0014	0.0011	0.0009
Loa Loa (eye worm)	intermediate filament protein	0.0026	0.0109	0.0109
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Echinococcus multilocularis	General substrate transporter	0.0046	0.0271	0.0478
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Echinococcus granulosus	sodium:potassium dependent atpase beta subunit	0.0069	0.0452	0.0796
Echinococcus granulosus	intermediate filament protein	0.0026	0.0109	0.0192
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0044	0.0256	0.045
Toxoplasma gondii	adenylate cyclase, putative	0.0029	0.0129	0.4005
Mycobacterium leprae	Probable lipase LipE	0.004	0.0221	1
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0129	0.0129
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0129	0.0129
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Schistosoma mansoni	receptor-type adenylate cyclase	0.0029	0.0129	0.0216
Mycobacterium ulcerans	adenylate cyclase	0.0029	0.0129	0.5709
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0051	0.0312	0.055
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Echinococcus multilocularis	lamin dm0	0.0026	0.0109	0.0192
Brugia malayi	Ets-domain containing protein	0.0081	0.0547	0.1018
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Echinococcus multilocularis	calcium transporting ATPase type 2C member	0.0013	0.0006	0.0011
Plasmodium vivax	hexose transporter	0.0051	0.0312	1
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0051	0.0312	0.055
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Mycobacterium ulcerans	beta-lactamase	0.004	0.0221	1
Brugia malayi	Fli-1 protein	0.0245	0.1868	0.3505
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.004	0.0221	0.0503
Loa Loa (eye worm)	beta-lactamase	0.004	0.0221	0.0221
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Echinococcus granulosus	nervana 2	0.0069	0.0452	0.0796
Brugia malayi	Sodium/potassium-transporting ATPase alpha chain, putative	0.0031	0.0144	0.0258
Echinococcus granulosus	receptor type guanylyl cyclase	0.0029	0.0129	0.0227
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0256	0.1959	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0029	0.0129	0.0231
Trichomonas vaginalis	D-aminoacylase, putative	0.004	0.0221	0.7015
Schistosoma mansoni	soluble guanylate cyclase gcy	0.0029	0.0129	0.0216
Trypanosoma cruzi	hypothetical protein, conserved	0.004	0.0221	1
Loa Loa (eye worm)	Na,K-ATPase alpha subunit	0.0035	0.0183	0.0183
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	procyclic-enriched flagellar receptor adenylate cyclase 1	0.0029	0.0129	0.5709
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0051	0.0312	0.055
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Plasmodium falciparum	guanylyl cyclase beta	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Echinococcus granulosus	General substrate transporter	0.0046	0.0271	0.0478
Leishmania major	receptor-type adenylate cyclase a-like protein	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Echinococcus multilocularis	microtubule associated protein 2	0.0719	0.5677	1
Onchocerca volvulus		0.0069	0.0452	0.0658
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Echinococcus granulosus	calcium transporting atpase	0.0013	0.0006	0.0011
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0044	0.0256	0.0469
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Echinococcus multilocularis	adenylate cyclase 9	0.0029	0.0129	0.0227
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.004	0.0221	0.0404
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Echinococcus granulosus	adenylate cyclase 9	0.0674	0.5318	0.9367
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Echinococcus granulosus	adenylate cyclase type IX	0.0611	0.4811	0.8475
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0029	0.0129	0.0227
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Onchocerca volvulus		0.0029	0.0129	0.0038
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	conserved hypothetical protein	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	soluble guanylate cyclase gcy, putative	0.0029	0.0129	0.4005
Onchocerca volvulus		0.004	0.0221	0.0215
Mycobacterium tuberculosis	Probable lipase LipD	0.004	0.0221	0.0503
Loa Loa (eye worm)	hypothetical protein	0.004	0.0221	0.0221
Loa Loa (eye worm)	hypothetical protein	0.004	0.0221	0.0221
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	procyclic-enriched flagellar receptor adenylate cyclase 3	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate and guanylate cyclases, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Echinococcus granulosus	sodium:potassium transporting ATPase subunit	0.0069	0.0452	0.0796
Schistosoma mansoni	sodium/potassium-dependent atpase beta subunit	0.0069	0.0452	0.0785
Onchocerca volvulus		0.0645	0.5087	0.9557
Trichomonas vaginalis	adenylyl cyclase type V, putative	0.0029	0.0129	0.4005
Echinococcus granulosus	Ca2 transporting ATPase plasma membrane	0.0013	0.0006	0.0011
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0029	0.0129	0.0129
Schistosoma mansoni	hypothetical protein	0.0051	0.0312	0.0539
Echinococcus multilocularis	calcium transporting atpase	0.0013	0.0006	0.0011
Mycobacterium ulcerans	adenylate cyclase	0.0029	0.0129	0.5709
Plasmodium vivax	adenylyl cyclase beta, putative	0.0029	0.0129	0.4005
Brugia malayi	beta-lactamase	0.004	0.0221	0.0404
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0105	0.0105
Trichomonas vaginalis	guanylate cyclase, putative	0.0029	0.0129	0.4005
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	soluble guanylate cyclase gcy, putative	0.0029	0.0129	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0119	0.0119
Echinococcus granulosus	lamin	0.0026	0.0109	0.0192
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0051	0.0312	0.055
Echinococcus granulosus	lamin dm0	0.0026	0.0109	0.0192
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0109	0.0109
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.0014	0.0011	0.0011
Loa Loa (eye worm)	hypothetical protein	0.004	0.0221	0.0221
Trichomonas vaginalis	conserved hypothetical protein	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.004	0.0221	0.0378
Trichomonas vaginalis	adenylate cyclase type, putative	0.0029	0.0129	0.4005
Onchocerca volvulus		0.0029	0.0129	0.0038
Mycobacterium ulcerans	adenylate cyclase	0.0029	0.0129	0.5709
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0029	0.0129	0.0231
Trypanosoma brucei	adenylyl cyclase	0.0029	0.0129	0.5709
Mycobacterium ulcerans	hypothetical protein	0.0029	0.0129	0.5709
Trichomonas vaginalis	soluble guanylate cyclase gcy, putative	0.0029	0.0129	0.4005
Mycobacterium leprae	PROBABLE CATION-TRANSPORTER ATPASE I CTPI	0.0029	0.0134	0.0501
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0029	0.0129	0.0227
Echinococcus multilocularis	nervana 2	0.0069	0.0452	0.0796
Echinococcus multilocularis	sodium:potassium transporting ATPase subunit	0.0069	0.0452	0.0796
Leishmania major	adenylate cyclase-like protein	0.0029	0.0129	0.5709
Trichomonas vaginalis	conserved hypothetical protein	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Trichomonas vaginalis	adenylate cyclase, putative	0.0029	0.0129	0.4005
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Leishmania major	receptor-type adenylate cyclase, putative	0.0029	0.0129	0.5709
Schistosoma mansoni	glucose transport protein	0.0051	0.0312	0.0539
Echinococcus granulosus	sodium:potassium dependent atpase beta subunit	0.0069	0.0452	0.0796
Trypanosoma brucei	receptor-type adenylate cyclase GRESAG 4, putative	0.0029	0.0129	0.5709
Mycobacterium ulcerans	adenylate cyclase	0.0029	0.0129	0.5709
Echinococcus granulosus	microtubule associated protein 2	0.0719	0.5677	1
Trypanosoma brucei	procyclic-enriched flagellar receptor adenylate cyclase 4	0.0029	0.0129	0.5709
Leishmania major	receptor-type adenylate cyclase b	0.0029	0.0129	0.5709

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL535129

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1031755