Detailed information for compound 1101888

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 347.387 | Formula: C13H21N3O6S
  • H donors: 4 H acceptors: 6 LogP: -1.91 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: SCC(=O)N[C@H](C(=O)N[C@H](C(=O)N)CCC(=O)C)CCC(=O)O
  • InChi: 1S/C13H21N3O6S/c1-7(17)2-3-8(12(14)21)16-13(22)9(4-5-11(19)20)15-10(18)6-23/h8-9,23H,2-6H2,1H3,(H2,14,21)(H,15,18)(H,16,22)(H,19,20)/t8-,9-/m0/s1
  • InChiKey: WCDYAIGZWIXDRE-IUCAKERBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax hypothetical protein, conserved 0.0068 0.0212 0.3769
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0287 0.111 0.3219
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0034 0.0097
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0059 0.017
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0857 0.3449 1
Onchocerca volvulus 0.0027 0.0042 0.0024
Trypanosoma cruzi oligopeptidase b 0.0068 0.0212 0.1898
Echinococcus granulosus survival motor neuron protein 1 0.0487 0.1932 0.2541
Brugia malayi beta-lactamase family protein 0.015 0.0548 0.1589
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0082 0.0108
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0083 0.0082
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0068 0.0212 0.1898
Loa Loa (eye worm) hypothetical protein 0.0054 0.0156 0.0453
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.015 0.0548 0.1589
Mycobacterium tuberculosis Probable hydrolase 0.015 0.0548 0.0973
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.1868 0.7602 0.7602
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0082 0.0081
Trichomonas vaginalis set domain proteins, putative 0.0258 0.0991 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.017
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0115
Loa Loa (eye worm) hypothetical protein 0.022 0.0836 0.2425
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0068 0.0212 0.0371
Brugia malayi prolyl oligopeptidase family protein 0.0068 0.0212 0.0614
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0076 0.0244 0.254
Brugia malayi prolyl oligopeptidase family protein 0.0857 0.3449 1
Giardia lamblia Serine peptidase, putative 0.01 0.0345 1
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0083 0.0841
Trichomonas vaginalis inositol monophosphatase, putative 0.0076 0.0244 0.2461
Loa Loa (eye worm) hypothetical protein 0.0063 0.019 0.0552
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0024
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.017
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0059 0.017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0287 0.111 0.146
Loa Loa (eye worm) hypothetical protein 0.005 0.0139 0.0403
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0059 0.0077
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0288 0.1115 0.1114
Schistosoma mansoni Smad4 0.0025 0.0036 0.0047
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0036 0.0047
Echinococcus granulosus GPCR family 2 0.0081 0.0265 0.0347
Mycobacterium ulcerans esterase/lipase LipP 0.015 0.0548 0.0966
Schistosoma mansoni hypothetical protein 0.0166 0.0613 0.0806
Trichomonas vaginalis penicillin-binding protein, putative 0.015 0.0548 0.5533
Brugia malayi latrophilin 2 splice variant baaae 0.0175 0.065 0.1885
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0059 0.0058
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0226 0.0862 0.25
Echinococcus granulosus smad 0.0025 0.0036 0.0045
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0082 0.0238
Onchocerca volvulus 0.0032 0.0066 0.0096
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0068 0.0212 0.0278
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0034 0.0046
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0244 0.1565
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0024
Trypanosoma brucei PAB1-binding protein , putative 0.0082 0.0269 0.181
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0008 0.0007
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0036 0.0035
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0066 0.0065
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0068 0.0211 0.0377
Entamoeba histolytica prolyl oligopeptidase family protein 0.0068 0.0212 0.2151
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0083 0.0242
Schistosoma mansoni hypothetical protein 0.0037 0.0084 0.011
Plasmodium vivax SET domain protein, putative 0.0032 0.0066 0.1076
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0082 0.0587
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0234 0.0679
Loa Loa (eye worm) hypothetical protein 0.0068 0.0212 0.0614
Onchocerca volvulus 0.0095 0.0325 0.0853
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0034 0.0301
Trypanosoma cruzi hypothetical protein, conserved 0.015 0.0548 0.4916
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0059 0.0077
Schistosoma mansoni hypothetical protein 0.0081 0.0265 0.0348
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0178 0.1594
Echinococcus granulosus tumor protein p63 0.0343 0.134 0.1762
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0097
Brugia malayi Inositol-1 0.0076 0.0244 0.0707
Mycobacterium leprae Probable transcriptional regulatory repressor protein (TetR-family) EthR 0.138 0.5596 1
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0068 0.0212 0.2136
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0287 0.111 0.1109
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0037 0.0084 0.0109
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.1868 0.7602 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0059 0.0058
Onchocerca volvulus 0.0031 0.0059 0.0074
Giardia lamblia Thymus-specific serine protease precursor 0.01 0.0345 1
Loa Loa (eye worm) RNA binding protein 0.0203 0.0768 0.2227
Loa Loa (eye worm) hypothetical protein 0.0027 0.0042 0.0121
Loa Loa (eye worm) inositol-1 0.0076 0.0244 0.0707
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0082 0.0737
Loa Loa (eye worm) beta-lactamase 0.015 0.0548 0.1589
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0082 0.0829
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0178 0.5
Entamoeba histolytica hypothetical protein, conserved 0.0068 0.0212 0.2151
Mycobacterium leprae conserved hypothetical protein 0.015 0.0548 0.0979
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0068 0.0212 0.1898
Brugia malayi MH2 domain containing protein 0.0367 0.144 0.4175
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0036 0.0035
Schistosoma mansoni tar DNA-binding protein 0.0203 0.0768 0.101
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.01 0.0345 0.3483
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0059 0.0077
Echinococcus multilocularis tar DNA binding protein 0.0203 0.0768 0.0767
Brugia malayi hypothetical protein 0.0487 0.1932 0.5604
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0957 0.3863 0.69
Echinococcus granulosus geminin 0.0166 0.0613 0.0804
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0082 0.0108
Onchocerca volvulus 0.015 0.0548 0.1507
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0288 0.1115 1
Trichomonas vaginalis D-aminoacylase, putative 0.015 0.0548 0.5533
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0038 0.009 0.0262
Loa Loa (eye worm) hypothetical protein 0.015 0.0548 0.1589
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0068 0.0212 0.0278
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.01 0.0345 0.3763
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0034 0.0053
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0081 0.0265 0.0347
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0287 0.111 0.1459
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0068 0.0212 0.0278
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0234 0.0233
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.01 0.0345 0.0453
Brugia malayi MH2 domain containing protein 0.0025 0.0036 0.0103
Toxoplasma gondii ABC1 family protein 0.015 0.0548 0.4595
Brugia malayi Ets-domain containing protein 0.0073 0.0234 0.0679
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.01 0.0345 0.3483
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0059 0.017
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0083 0.0841
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.01 0.0345 0.3095
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0178 0.0232
Schistosoma mansoni hypothetical protein 0.0081 0.0265 0.0348
Trypanosoma cruzi hypothetical protein, conserved 0.0068 0.0212 0.1898
Entamoeba histolytica hypothetical protein 0.0226 0.0861 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0287 0.111 0.1459
Brugia malayi hypothetical protein 0.022 0.0836 0.2425
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0244 0.2187
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0244 0.2187
Brugia malayi Serine carboxypeptidase S28 family protein 0.01 0.0345 0.1001
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0178 0.0515
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.01 0.0345 0.3095
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.01 0.0345 0.3763
Echinococcus multilocularis acylamino acid releasing enzyme 0.0068 0.0212 0.0211
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.015 0.0548 0.0721
Schistosoma mansoni tar DNA-binding protein 0.0203 0.0768 0.101
Trichomonas vaginalis conserved hypothetical protein 0.01 0.0345 0.3483
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0178 0.1742
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.015 0.0548 0.0966
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0055 0.0157 0.0456
Trypanosoma cruzi hypothetical protein, conserved 0.015 0.0548 0.4916
Echinococcus multilocularis neuropeptide receptor A26 0.0452 0.1788 0.1787
Brugia malayi RNA binding protein 0.0203 0.0768 0.2227
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0178 0.1795
Loa Loa (eye worm) TAR-binding protein 0.0203 0.0768 0.2227
Brugia malayi RNA recognition motif domain containing protein 0.0203 0.0768 0.2227
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0083 0.0841
Trypanosoma cruzi hypothetical protein, conserved 0.0068 0.0212 0.1898
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0857 0.3449 0.3448
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0083 0.0747
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0059 0.0076
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.01 0.0345 0.3483
Schistosoma mansoni tar DNA-binding protein 0.0203 0.0768 0.101
Mycobacterium ulcerans beta-lactamase 0.015 0.0548 0.0966
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0178 0.3637
Brugia malayi prolyl oligopeptidase family protein 0.0068 0.0212 0.0614
Echinococcus multilocularis beta LACTamase domain containing family member 0.015 0.0548 0.0547
Brugia malayi hypothetical protein 0.0054 0.0156 0.0453
Loa Loa (eye worm) hypothetical protein 0.0082 0.0269 0.078
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0082 0.0737
Mycobacterium tuberculosis Probable lipase LipD 0.015 0.0548 0.0973
Brugia malayi TAR-binding protein 0.0203 0.0768 0.2227
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0287 0.111 0.146
Mycobacterium tuberculosis Probable esterase LipL 0.015 0.0548 0.0973
Brugia malayi follicle stimulating hormone receptor 0.0234 0.0893 0.259
Brugia malayi hypothetical protein 0.0226 0.0861 0.2498
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.01 0.0345 0.3483
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0059 0.017
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.01 0.0345 0.3483
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0192
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0034 0.0301
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0024
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0059 0.0058
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0841
Schistosoma mansoni smad1 5 8 and 0.0025 0.0036 0.0047
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0178 0.1594
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.01 0.0345 0.0344
Brugia malayi MH2 domain containing protein 0.0025 0.0036 0.0103
Schistosoma mansoni lamin 0.0027 0.0042 0.0055
Trypanosoma cruzi oligopeptidase b 0.0068 0.0212 0.1898
Mycobacterium ulcerans transcriptional regulator 0.138 0.5596 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0059 0.0077
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0203 0.0768 0.2227
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.017
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0082 0.0081
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0059 0.0058
Schistosoma mansoni inositol monophosphatase 0.0076 0.0244 0.0321
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0857 0.3449 0.4536
Trichomonas vaginalis esterase, putative 0.015 0.0548 0.5533
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0036 0.0103
Echinococcus multilocularis Smad4 0.0025 0.0036 0.0035
Echinococcus granulosus neuropeptide receptor A26 0.0452 0.1788 0.2351
Mycobacterium leprae Probable lipase LipE 0.015 0.0548 0.0979
Echinococcus granulosus acylamino acid releasing enzyme 0.0068 0.0212 0.0277
Schistosoma mansoni hypothetical protein 0.0226 0.0861 0.1133
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0059 0.017
Loa Loa (eye worm) MH2 domain-containing protein 0.0367 0.144 0.4175
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.01 0.0345 0.3483
Mycobacterium ulcerans hypothetical protein 0.0025 0.0034 0.0046
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0037 0.0084 0.0083
Entamoeba histolytica hypothetical protein 0.0226 0.0861 1
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0082 0.0107
Trypanosoma brucei prolyl oligopeptidase, putative 0.0068 0.0212 0.1253
Loa Loa (eye worm) hypothetical protein 0.0154 0.0565 0.1639
Schistosoma mansoni ap endonuclease 0.006 0.0178 0.0234
Schistosoma mansoni coup transcription factor 0.0031 0.0059 0.0077
Brugia malayi MH1 domain containing protein 0.0025 0.0036 0.0103
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0083 0.0163
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0841
Mycobacterium ulcerans AcrR family transcriptional regulator 0.138 0.5596 1
Brugia malayi intermediate filament protein 0.0027 0.0042 0.0121
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.017
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.0244 0.2461
Mycobacterium tuberculosis Transcriptional regulatory repressor protein (TetR-family) EthR 0.138 0.5596 1
Brugia malayi beta-lactamase 0.015 0.0548 0.1589
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0083 0.0108
Loa Loa (eye worm) hypothetical protein 0.0038 0.0089 0.0259
Loa Loa (eye worm) hypothetical protein 0.015 0.0548 0.1589
Brugia malayi Pre-SET motif family protein 0.0226 0.0862 0.25
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0059 0.017
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0036 0.0045
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0288 0.1115 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0059 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0059 0.017
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0059 0.0076
Echinococcus granulosus intermediate filament protein 0.0027 0.0042 0.0053
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0288 0.1115 1
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0068 0.0212 0.0364
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0082 0.0107
Onchocerca volvulus 0.0258 0.0991 0.2802
Loa Loa (eye worm) hypothetical protein 0.0175 0.065 0.1885
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0059 0.0076
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0059 0.0077
Brugia malayi Serine protease Z688.6 precursor 0.01 0.0345 0.1001
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0082 0.0737
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0081 0.0265 0.0264
Loa Loa (eye worm) hypothetical protein 0.0038 0.0089 0.0259
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0034 0.0053
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0269 0.2413
Loa Loa (eye worm) hypothetical protein 0.015 0.0548 0.1589
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.0244 0.2461
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0081 0.0265 0.0264
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0034 0.006
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0034 0.0046
Loa Loa (eye worm) hypothetical protein 0.0487 0.1932 0.5604
Brugia malayi MH1 domain containing protein 0.0025 0.0036 0.0103
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0059 0.0074
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0024
Schistosoma mansoni alpha-glucosidase 0.0142 0.0516 0.0679
Echinococcus multilocularis tumor protein p63 0.0343 0.134 0.1339
Schistosoma mansoni ets-related 0.0223 0.0847 0.1114
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0068 0.0212 0.1253
Onchocerca volvulus Prolyl endopeptidase homolog 0.0068 0.0212 0.0521
Echinococcus granulosus beta LACTamase domain containing family member 0.015 0.0548 0.072
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.015 0.0548 0.0973
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0178 0.1795
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0034 0.0301
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.0893 0.259
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0256 0.0982 0.2847
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.0341 0.0988
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0082 0.0107
Loa Loa (eye worm) hypothetical protein 0.015 0.0548 0.1589
Schistosoma mansoni smad1 5 8 and 0.0025 0.0036 0.0047
Entamoeba histolytica hypothetical protein 0.0226 0.0861 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.01 0.0345 0.3483
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0034 0.006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0059 0.0076
Mycobacterium tuberculosis Conserved protein 0.015 0.0548 0.0973
Onchocerca volvulus 0.0099 0.0341 0.09
Plasmodium vivax ataxin-2 like protein, putative 0.0082 0.0269 0.4832
Loa Loa (eye worm) fli-1 protein 0.0223 0.0847 0.2457
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0034 0.0046
Plasmodium falciparum peptidase, putative 0.0068 0.0212 0.7798
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0068 0.0211 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.01 0.0345 0.3483
Schistosoma mansoni aryl hydrocarbon receptor 0.0017 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0059 0.017
Schistosoma mansoni hypothetical protein 0.0166 0.0613 0.0806
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0244 0.2187
Brugia malayi hypothetical protein 0.0053 0.015 0.0435
Trypanosoma brucei glucosidase, putative 0.0037 0.0083 0.0011
Mycobacterium ulcerans TetR family transcriptional regulator 0.138 0.5596 1
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0038 0.009 0.0262
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.017
Loa Loa (eye worm) prolyl oligopeptidase 0.0857 0.3449 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0226 0.0861 0.1132
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0097
Onchocerca volvulus 0.015 0.0548 0.1507
Schistosoma mansoni smad 0.0025 0.0036 0.0047
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.017
Brugia malayi nuclear receptor NHR-88 0.0031 0.0059 0.017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0059 0.017
Loa Loa (eye worm) hypothetical protein 0.0038 0.0089 0.0259
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0059 0.017
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.061 0.177
Trypanosoma cruzi PAB1-binding protein , putative 0.0082 0.0269 0.2413
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0066 0.0087
Echinococcus granulosus lamin dm0 0.0027 0.0042 0.0053
Echinococcus multilocularis geminin 0.0166 0.0613 0.0612
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0059 0.017
Echinococcus granulosus aryl hydrocarbon receptor 0.0055 0.0157 0.0206
Echinococcus multilocularis inositol monophosphatase 1 0.0076 0.0244 0.0243
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0841
Echinococcus multilocularis musashi 0.0027 0.0042 0.0041
Echinococcus granulosus lamin 0.0027 0.0042 0.0053
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0034 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0059 0.017
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.061 0.0802
Schistosoma mansoni transcription factor LCR-F1 0.0226 0.0861 0.1133
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.1868 0.7602 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0081 0.0265 0.0768
Echinococcus granulosus Dipeptidyl peptidase 9 0.0288 0.1115 0.1465
Trypanosoma brucei oligopeptidase b 0.0068 0.0212 0.1253
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0178 0.0926
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0076 0.0244 1
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0068 0.0212 0.1253
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0288 0.1115 0.1467
Mycobacterium ulcerans short chain dehydrogenase 0.0281 0.1086 0.1929
Giardia lamblia Alanyl dipeptidyl peptidase 0.0068 0.0212 0.4924
Echinococcus multilocularis aryl hydrocarbon receptor 0.0055 0.0157 0.0156
Plasmodium falciparum ataxin-2 like protein, putative 0.0082 0.0269 1
Trichomonas vaginalis D-aminoacylase, putative 0.015 0.0548 0.5533
Mycobacterium tuberculosis Probable peptidase 0.0068 0.0212 0.0371
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0034 0.0097
Schistosoma mansoni smad1 5 8 and 0.0025 0.0036 0.0047
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0083 0.0601
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0178 0.1594
Mycobacterium tuberculosis Probable lipase LipE 0.015 0.0548 0.0973
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0036 0.0103
Schistosoma mansoni hypothetical protein 0.0175 0.065 0.0855
Brugia malayi hypothetical protein 0.0038 0.0089 0.0259
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0287 0.111 0.1109
Giardia lamblia Alanyl dipeptidyl peptidase 0.0068 0.0212 0.4924
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0059 0.0077
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.017
Loa Loa (eye worm) latrophilin receptor protein 2 0.0081 0.0265 0.0768
Schistosoma mansoni hypothetical protein 0.0081 0.0265 0.0348
Loa Loa (eye worm) hypothetical protein 0.01 0.0345 0.1001
Mycobacterium tuberculosis Probable oxidoreductase 0.0281 0.1086 0.1935
Loa Loa (eye worm) hypothetical protein 0.015 0.0548 0.1589
Schistosoma mansoni hypothetical protein 0.0099 0.0341 0.0448
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.015 0.0548 0.0721
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0059 0.0058
Echinococcus granulosus prolyl endopeptidase 0.0068 0.0212 0.0277
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.015 0.0548 0.0973
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0036 0.0045
Schistosoma mansoni gabp alpha 0.0073 0.0234 0.0308
Brugia malayi hypothetical protein 0.0082 0.0269 0.078
Mycobacterium ulcerans hypothetical protein 0.015 0.0548 0.0966
Brugia malayi prolyl oligopeptidase family protein 0.0068 0.0212 0.0614
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0034 0.0046
Trichomonas vaginalis penicillin-binding protein, putative 0.015 0.0548 0.5533
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0066 0.0086
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0059 0.0076
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.01 0.0345 0.3483
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.061 0.0609
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0034 0.0046
Leishmania major hypothetical protein, conserved 0.0082 0.0269 0.2413
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0059 0.017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0082 0.0829
Loa Loa (eye worm) hypothetical protein 0.0036 0.0082 0.0238
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0059 0.017
Echinococcus granulosus neuropeptide s receptor 0.0452 0.1788 0.2351
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0097
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0059 0.0058
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.01 0.0345 0.3483
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.01 0.0345 0.3763
Onchocerca volvulus 0.005 0.0139 0.0309
Schistosoma mansoni intermediate filament proteins 0.0027 0.0042 0.0055
Echinococcus granulosus Smad4 0.0025 0.0036 0.0045
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0042 0.0121
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0076 0.0244 0.0422
Brugia malayi ecdysteroid receptor 0.0031 0.0059 0.017
Echinococcus multilocularis smad 0.0025 0.0036 0.0035
Brugia malayi Serine protease Z688.6 precursor 0.01 0.0345 0.1001
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.061 0.177
Loa Loa (eye worm) hypothetical protein 0.0081 0.0265 0.0768
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0234 0.0307
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0068 0.0212 0.2151
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0038 0.009 0.0119
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.01 0.0345 0.3483
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0059 0.017
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.01 0.0345 0.3483
Echinococcus multilocularis lamin dm0 0.0027 0.0042 0.0041
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0083 0.0841
Echinococcus multilocularis neuropeptide s receptor 0.0452 0.1788 0.1787
Brugia malayi Fli-1 protein 0.0223 0.0847 0.2457
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0042 0.0121
Mycobacterium tuberculosis Probable conserved lipoprotein 0.015 0.0548 0.0973
Entamoeba histolytica prolyl oligopeptidase family protein 0.0068 0.0212 0.2151
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0082 0.0081
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0178 0.6502
Loa Loa (eye worm) Smad1 0.0025 0.0036 0.0103
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0059 0.0076
Loa Loa (eye worm) hypothetical protein 0.01 0.0345 0.1001
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0139 0.0183
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.01 0.0345 0.3483
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0068 0.0212 0.2151
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0059 0.017
Toxoplasma gondii LsmAD domain-containing protein 0.0082 0.0269 0.1934
Schistosoma mansoni lamin 0.0027 0.0042 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0059 0.017
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0059 0.017
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0059 0.0076
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0068 0.0212 0.1386
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0083 0.0242
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0059 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0212 0.2136
Mycobacterium ulcerans lipase LipD 0.015 0.0548 0.0966
Schistosoma mansoni inositol monophosphatase 0.0076 0.0244 0.0321
Leishmania major hypothetical protein, conserved 0.015 0.0548 0.4916
Onchocerca volvulus 0.0154 0.0565 0.1557
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0288 0.1115 1
Schistosoma mansoni tar DNA-binding protein 0.0203 0.0768 0.101
Brugia malayi beta-lactamase family protein 0.015 0.0548 0.1589
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.017
Brugia malayi Calcitonin receptor-like protein seb-1 0.0256 0.0982 0.2847
Brugia malayi prolyl oligopeptidase family protein 0.0288 0.1115 0.3233
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0068 0.0212 0.0378
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0042 0.0121
Toxoplasma gondii prolyl endopeptidase 0.0068 0.0212 0.1386
Loa Loa (eye worm) hypothetical protein 0.0256 0.0982 0.2847
Onchocerca volvulus 0.0054 0.0156 0.0359
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0059 0.0077
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0059 0.0074
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0066 0.0087
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0076 0.0244 0.1693
Toxoplasma gondii hypothetical protein 0.0068 0.0212 0.1386
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0068 0.0212 0.1898
Echinococcus granulosus tar DNA binding protein 0.0203 0.0768 0.1009
Schistosoma mansoni ap endonuclease 0.006 0.0178 0.0234
Onchocerca volvulus 0.0027 0.0042 0.0024
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0059 0.017
Brugia malayi hypothetical protein 0.0154 0.0565 0.1639
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0066 0.0065
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0841
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0178 0.0177
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0066 0.0087
Brugia malayi Pre-SET motif family protein 0.0032 0.0066 0.0192
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.01 0.0345 0.3483
Trypanosoma brucei prolyl endopeptidase 0.0068 0.0212 0.1253
Onchocerca volvulus 0.01 0.0345 0.0912
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0059 0.0077
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0288 0.1115 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0082 0.0269 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.061 0.0609
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0059 0.0077
Brugia malayi hypothetical protein 0.0038 0.009 0.0262
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0059 0.0058
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.015 0.0548 0.1589
Schistosoma mansoni survival motor neuron protein 0.0099 0.0341 0.0448
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.01 0.0345 0.3483
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0038 0.009 0.0262
Loa Loa (eye worm) hypothetical protein 0.015 0.0548 0.1589
Echinococcus multilocularis prolyl endopeptidase 0.0068 0.0212 0.0211
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0059 0.0074
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0038 0.0089 0.0259
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0059 0.0077
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0288 0.1115 1
Loa Loa (eye worm) hypothetical protein 0.01 0.0345 0.1001
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.01 0.0345 0.3483
Echinococcus multilocularis lamin 0.0027 0.0042 0.0041
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0178 0.0311
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0059 0.017
Schistosoma mansoni hypothetical protein 0.0081 0.0265 0.0348
Loa Loa (eye worm) hypothetical protein 0.0038 0.0089 0.0259
Brugia malayi Ets-domain containing protein 0.0073 0.0234 0.0679
Echinococcus multilocularis GPCR, family 2 0.0081 0.0265 0.0264
Plasmodium vivax hypothetical protein, conserved 0.015 0.0548 1
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0034 0.0097
Mycobacterium tuberculosis Conserved protein 0.015 0.0548 0.0973
Brugia malayi Latrophilin receptor protein 2 0.0081 0.0265 0.0768
Brugia malayi nuclear hormone receptor 0.0031 0.0059 0.017
Loa Loa (eye worm) hypothetical protein 0.0068 0.0212 0.0614
Echinococcus multilocularis survival motor neuron protein 1 0.0487 0.1932 0.1932
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0287 0.111 0.3219
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0841
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0178 0.0515
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0083 0.0747
Loa Loa (eye worm) prolyl oligopeptidase 0.0068 0.0212 0.0614
Loa Loa (eye worm) hypothetical protein 0.01 0.0345 0.1001
Toxoplasma gondii serine carboxypeptidase s28 protein 0.01 0.0345 0.2659
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0066 0.0087
Toxoplasma gondii exonuclease III APE 0.006 0.0178 0.1064
Echinococcus granulosus inositol monophosphatase 1 0.0076 0.0244 0.0319
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0083 0.0601
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0082 0.0829
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0178 0.0304
Brugia malayi steroid hormone receptor 0.0031 0.0059 0.017
Brugia malayi Smad1 0.0025 0.0036 0.0103
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0059 0.0058
Schistosoma mansoni alpha glucosidase 0.0037 0.0083 0.011
Onchocerca volvulus Protein cycle homolog 0.0038 0.009 0.0166
Trichomonas vaginalis D-aminoacylase, putative 0.015 0.0548 0.5533
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0857 0.3449 0.4536
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0059 0.017
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0059 0.017
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.01 0.0345 0.0454
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0068 0.0212 0.0278
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0059 0.0058
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0061 0.0079
Trypanosoma brucei hypothetical protein, conserved 0.015 0.0548 0.4511
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0008 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0178 0.3142
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0287 0.111 0.146
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0059 0.017
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0256 0.0982 0.2847
Schistosoma mansoni alpha-glucosidase 0.0142 0.0516 0.0679
Leishmania major oligopeptidase b 0.0068 0.0212 0.1898
Mycobacterium tuberculosis Conserved protein 0.015 0.0548 0.0973
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0059 0.017
Loa Loa (eye worm) hypothetical protein 0.0068 0.0212 0.0614
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0083 0.0747
Entamoeba histolytica hypothetical protein 0.0226 0.0861 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0081 0.0265 0.0347
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0068 0.0212 0.1898
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0068 0.0212 0.2136
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0034 0.0046
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.01 0.0345 0.3095
Schistosoma mansoni tar DNA-binding protein 0.0203 0.0768 0.101
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0226 0.0861 0.086
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0059 0.0077
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0059 0.0076
Onchocerca volvulus 0.015 0.0548 0.1507
Trypanosoma cruzi prolyl endopeptidase 0.0068 0.0212 0.1898
Entamoeba histolytica prolyl oligopeptidase family protein 0.0068 0.0212 0.2151
Loa Loa (eye worm) transcription factor SMAD2 0.0367 0.144 0.4175

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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