Detailed information for compound 1143839

Basic information

Technical information
  • TDR Targets ID: 1143839
  • Name: 2-hexylsulfanylcarbonyloxyethyl-trimethylazan ium
  • MW: 248.405 | Formula: C12H26NO2S+
  • H donors: 0 H acceptors: 1 LogP: 3.45 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCSC(=O)OCC[N+](C)(C)C
  • InChi: 1S/C12H26NO2S/c1-5-6-7-8-11-16-12(14)15-10-9-13(2,3)4/h5-11H2,1-4H3/q+1
  • InChiKey: MYPUMOKORCCVMS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-hexylsulfanylcarbonyloxyethyl-trimethyl-ammonium
  • 2-[(hexylthio)-oxomethoxy]ethyl-trimethylammonium
  • 2-(hexylthio)carbonyloxyethyl-trimethyl-ammonium
  • 2-hexylsulfanylcarbonyloxyethyl-trimethyl-azanium

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0735 0.0804
Echinococcus multilocularis geminin 0.0337 0.504 0.5017
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0745 0.071
Loa Loa (eye worm) hypothetical protein 0.0025 0.0185 0.014
Echinococcus granulosus dna polymerase eta 0.0059 0.0718 0.0675
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0084 0.1101 0.3047
Loa Loa (eye worm) hypothetical protein 0.005 0.0572 0.0529
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0093 0.0055
Loa Loa (eye worm) hypothetical protein 0.0021 0.0126 0.0081
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0819 0.0783
Trypanosoma brucei polo-like protein kinase 0.0095 0.1277 0.1397
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1482 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0059 0.0725 0.0683
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0093 0.0101
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0093 0.0047
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0426 0.0232
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1277 0.3687
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0154 0.0116
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0025 0.0185 0.047
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0173 0.0128
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.1265 0.1225
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1482 0.4279
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0045 0.0505 0.3618
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0096 0.0371
Schistosoma mansoni hypothetical protein 0.0016 0.0046 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0725 0.2095
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0154 0.0445
Mycobacterium ulcerans hypothetical protein 0.0317 0.4719 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0059 0.0725 0.0683
Schistosoma mansoni bromodomain containing protein 0.0063 0.078 0.0744
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0154 0.0831
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0154 0.0445
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0065 0.0027
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.1482 0.1622
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.1009 0.2914
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.0703 0.066
Entamoeba histolytica hypothetical protein 0.005 0.0576 0.389
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1277 0.3687
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0085 0.1117 0.3226
Entamoeba histolytica hypothetical protein 0.0023 0.0154 0.1041
Schistosoma mansoni serine/threonine protein kinase 0.041 0.6165 0.6151
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0121 0.0075
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0059 0.0725 0.0683
Entamoeba histolytica deoxycytidyl transferase, putative 0.0034 0.0324 0.2185
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0154 0.0831
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0093 0.0047
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.1482 0.1875
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0154 0.0955
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0922 0.0887
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0735 0.0804
Echinococcus granulosus G protein coupled receptor kinase 1 0.035 0.5242 0.522
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0154 0.0445
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.1482 0.1622
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0085 0.1117 0.1222
Brugia malayi Phosphoglycerate kinase 0.0031 0.0285 0.0804
Trypanosoma brucei unspecified product 0.0023 0.0162 0.0177
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0185 0.0535
Echinococcus multilocularis expressed protein 0.0412 0.6198 0.6181
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0256 0.0644
Loa Loa (eye worm) heterochromatin protein 1 0.0139 0.1956 0.1919
Giardia lamblia PHD finger protein 15 0.0058 0.0703 0.4743
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0735 0.0804
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0154 0.0445
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.1265 0.1225
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0095 0.1277 0.1237
Leishmania major hypothetical protein, conserved 0.0025 0.0185 0.0203
Loa Loa (eye worm) hypothetical protein 0.012 0.1669 0.1631
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.1482 0.1622
Brugia malayi RNA binding protein 0.0065 0.0819 0.26
Brugia malayi Regulator of G protein signaling domain containing protein 0.0059 0.0725 0.2287
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1277 0.3687
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0154 0.0445
Loa Loa (eye worm) jmjC domain-containing protein 0.012 0.1663 0.1624
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.1277 0.1397
Schistosoma mansoni axis inhibition protein axin 0.0059 0.0725 0.069
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.041 0.6165 0.6148
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1277 0.3687
Schistosoma mansoni metabotropic glutamate receptor 0.0051 0.0594 0.0558
Leishmania major DNA polymerase eta, putative 0.0059 0.0718 0.0785
Echinococcus granulosus axis inhibition protein axin 0.0059 0.0725 0.0683
Brugia malayi phosphofructokinase 0.0108 0.1482 0.4831
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0045 0.0505 0.2927
Schistosoma mansoni hypothetical protein 0.0016 0.0046 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1482 0.4279
Brugia malayi Pre-SET motif family protein 0.003 0.0263 0.0732
Schistosoma mansoni hypothetical protein 0.0024 0.0181 0.0143
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0154 0.0445
Echinococcus multilocularis phosphoglycerate kinase 1 0.0085 0.1117 0.1076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0154 0.0445
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0027 0.0219 0.0174
Schistosoma mansoni hypothetical protein 0.0016 0.0046 0.0007
Echinococcus granulosus jumonji domain containing protein 0.0081 0.1056 0.1015
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0735 0.0804
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0031 0.0285 0.0311
Brugia malayi serine/threonine-protein kinase plk-2 0.0095 0.1277 0.4142
Brugia malayi PHD-finger family protein 0.0021 0.0126 0.027
Loa Loa (eye worm) hypothetical protein 0.0023 0.0154 0.0109
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0025 0.0184 0.0139
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.1482 0.1443
Echinococcus multilocularis dna polymerase kappa 0.006 0.0735 0.0692
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.054 0.1558
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0154 0.0445
Schistosoma mansoni importin beta-1 0.0062 0.0757 0.0722
Leishmania major hypothetical protein, conserved 0.0015 0.0038 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0264 0.0289
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0096 0.041
Loa Loa (eye worm) glutamate receptor 0.0105 0.1428 0.1389
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0093 0.0342
Giardia lamblia Kinase, PLK 0.0095 0.1277 1
Brugia malayi SET domain containing protein 0.0024 0.0171 0.0423
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0154 0.0116
Loa Loa (eye worm) hypothetical protein 0.0059 0.0725 0.0683
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0819 0.0783
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0031 0.0285 0.0311
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0154 0.1041
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0084 0.111 0.9928
Giardia lamblia Phosphoglycerate kinase 0.0085 0.1117 0.8536
Brugia malayi Receptor family ligand binding region containing protein 0.0027 0.0219 0.0582
Brugia malayi jmjC domain containing protein 0.0019 0.0093 0.0158
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0703 0.611
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0154 0.0445
Loa Loa (eye worm) hypothetical protein 0.0019 0.0093 0.0047
Echinococcus granulosus chromobox protein 2 0.0023 0.0154 0.0109
Loa Loa (eye worm) glutamate receptor 0.0041 0.0441 0.0398
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0819 0.0777
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0358 0.0391
Loa Loa (eye worm) phosphofructokinase 0.0108 0.1482 0.1443
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0154 0.0445
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.1482 0.1449
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0093 0.0055
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0023 0.0154 0.0601
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0757 0.0828
Echinococcus granulosus Chromo domain 0.0023 0.0154 0.0109
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.0703 0.066
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0154 0.0445
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0256 0.0738
Echinococcus multilocularis peregrin 0.006 0.074 0.0697
Trichomonas vaginalis chromobox protein, putative 0.0139 0.1956 0.5647
Schistosoma mansoni phosphoglycerate kinase 0.0085 0.1117 0.1083
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0154 0.0445
Schistosoma mansoni DNA polymerase eta 0.0059 0.0718 0.0682
Loa Loa (eye worm) hypothetical protein 0.0023 0.0154 0.0109
Leishmania major importin beta-1 subunit, putative 0.005 0.0576 0.0631
Plasmodium vivax importin-beta 2, putative 0.0062 0.0757 0.6618
Brugia malayi jmjC domain containing protein 0.019 0.2753 0.9108
Schistosoma mansoni hypothetical protein 0.0058 0.0703 0.0667
Echinococcus granulosus phosphoglycerate kinase 1 0.0085 0.1117 0.1076
Brugia malayi jmjC domain containing protein 0.0019 0.0093 0.0158
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0025 0.0185 0.1078
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0725 0.2095
Schistosoma mansoni cpg binding protein 0.0035 0.0349 0.0312
Entamoeba histolytica hypothetical protein 0.0059 0.0725 0.4895
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1265 0.1231
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0357 0.0313
Echinococcus multilocularis axis inhibition protein axin 0.0059 0.0725 0.0683
Loa Loa (eye worm) hypothetical protein 0.0099 0.1347 0.1307
Loa Loa (eye worm) hypothetical protein 0.0059 0.0725 0.0683
Echinococcus granulosus peregrin 0.006 0.074 0.0697
Brugia malayi Metabotropic glutamate receptor precursor. 0.0105 0.1428 0.4649
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1277 0.3687
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0735 0.0804
Schistosoma mansoni hypothetical protein 0.0021 0.0121 0.0083
Trichomonas vaginalis chromobox protein, putative 0.0139 0.1956 0.5647
Brugia malayi 6-phosphofructokinase 0.0108 0.1482 0.4831
Echinococcus granulosus GPCR family 3 C terminal 0.0017 0.0066 0.002
Echinococcus granulosus GTP binding nuclear protein Ran 0.0045 0.0505 0.0461
Echinococcus granulosus chromobox protein 1 0.0139 0.1956 0.1919
Entamoeba histolytica phosphoglycerate kinase, putative 0.0085 0.1117 0.7538
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.006 0.0735 0.2122
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0184 0.0146
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.1482 0.1449
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0027 0.0219 0.0174
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.1265 0.4101
Trypanosoma brucei phosphoglycerate kinase, putative 0.0031 0.0285 0.0311
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0572 0.1772
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0154 0.0445
Brugia malayi Regulator of G protein signaling domain containing protein 0.0059 0.0725 0.2287
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0735 0.0804
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.002 0.0107 0.014
Trypanosoma cruzi importin beta-1 subunit, putative 0.005 0.0576 0.0631
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0154 0.0445
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0735 0.0804
Echinococcus multilocularis Chromo domain 0.0023 0.0154 0.0109
Brugia malayi hypothetical protein 0.0059 0.0725 0.2287
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0154 0.0445
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0527 0.049
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0154 0.0445
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0031 0.0285 0.0311
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0154 0.0445
Schistosoma mansoni ran 0.0045 0.0505 0.0468
Leishmania major mitochondrial DNA polymerase beta 0.0601 0.9138 1
Echinococcus granulosus cpg binding protein 0.0035 0.0349 0.0305
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.1265 0.1225
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0256 0.1591
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0093 0.0055
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.1482 0.2635
Loa Loa (eye worm) hypothetical protein 0.0034 0.0328 0.0284
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0256 0.0738
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0284 0.422 0.4618
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0725 0.2095
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0358 0.2447
Loa Loa (eye worm) hypothetical protein 0.0078 0.1009 0.0968
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0025 0.0185 0.014
Echinococcus multilocularis cpg binding protein 0.0035 0.0349 0.0305
Brugia malayi metabotropic glutamate receptor type 2 0.0051 0.0594 0.1846
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0263 0.1697
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0256 0.1591
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0093 0.0101
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0031 0.0285 0.0311
Brugia malayi chromobox protein homolog 3 0.0078 0.1009 0.3241
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.002 0.0107 0.0511
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0735 0.0804
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0256 0.0738
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0095 0.1275 0.4135
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0085 0.1117 0.8485
Loa Loa (eye worm) hypothetical protein 0.0058 0.0703 0.066
Trichomonas vaginalis Heterochromatin protein, putative 0.0023 0.0154 0.0445
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0061 0.0745 0.0703
Echinococcus multilocularis importin subunit beta 1 0.0062 0.0757 0.0715
Onchocerca volvulus 0.0023 0.0154 0.0261
Echinococcus multilocularis 0.0025 0.0185 0.014
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0025 0.0185 0.0905
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0031 0.0285 0.0311
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0096 0.0105
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0085 0.1117 0.8485
Toxoplasma gondii hypothetical protein 0.0097 0.1308 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0397 0.0353
Schistosoma mansoni serine/threonine protein kinase 0.041 0.6165 0.6151
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.1482 0.1443
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0154 0.0445
Toxoplasma gondii HEAT repeat-containing protein 0.0062 0.0757 0.5624
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0045 0.0505 0.0461
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0527 0.0483
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0154 0.1041
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0095 0.1277 0.1397
Trichomonas vaginalis dullard protein, putative 0.0025 0.0185 0.0535
Brugia malayi hypothetical protein 0.0059 0.0725 0.2287
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0095 0.1277 0.1237
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0093 0.0047
Echinococcus granulosus chromobox protein 1 0.0139 0.1956 0.1919
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0059 0.0725 0.0683
Brugia malayi Protein cec-1. 0.0023 0.0154 0.0366
Schistosoma mansoni kinase 0.0049 0.0559 0.0523
Echinococcus granulosus lysine specific demethylase 5A 0.0072 0.0922 0.0881
Echinococcus granulosus CTD small phosphatase protein like 0.0025 0.0185 0.014
Echinococcus granulosus tar DNA binding protein 0.0065 0.0819 0.0777
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0154 0.0955
Trypanosoma brucei phosphoglycerate kinase 0.0085 0.1117 0.1222
Echinococcus multilocularis axis inhibition protein axin 0.0059 0.0725 0.0683
Echinococcus multilocularis G protein coupled receptor kinase 1 0.035 0.5242 0.522
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0284 0.422 0.4618
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0025 0.0185 0.0148
Trichomonas vaginalis DNA polymerase eta, putative 0.006 0.0735 0.2122
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0527 0.0483
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0601 0.9138 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0128 0.0342
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0096 0.0105
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0085 0.1115 0.122
Brugia malayi PXA domain containing protein 0.0059 0.0725 0.2287
Loa Loa (eye worm) CHromoDomain protein family member 0.0025 0.0184 0.0139
Echinococcus granulosus geminin 0.0337 0.504 0.5017
Loa Loa (eye worm) RecQ helicase 0.0024 0.0173 0.0128
Loa Loa (eye worm) hypothetical protein 0.0047 0.0527 0.0483
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0725 0.2095
Echinococcus multilocularis chromobox protein 1 0.0139 0.1956 0.1919
Plasmodium falciparum importin beta, putative 0.0062 0.0757 0.6486
Chlamydia trachomatis phosphoglycerate kinase 0.0085 0.1117 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0725 0.0682
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0085 0.1117 0.1805
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1482 0.4279
Brugia malayi Bromodomain containing protein 0.006 0.074 0.2334
Schistosoma mansoni hypothetical protein 0.0016 0.0046 0.0007
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0034 0.0324 0.0279
Trichomonas vaginalis hypothetical protein 0.0023 0.0154 0.0445
Schistosoma mansoni chromobox protein 0.0023 0.0154 0.0116
Brugia malayi Bromodomain containing protein 0.0038 0.0394 0.1171
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.032 0.0275
Loa Loa (eye worm) hypothetical protein 0.0059 0.0725 0.0683
Echinococcus multilocularis chromobox protein 2 0.0023 0.0154 0.0109
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.019 0.2753 0.272
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.1482 0.1443
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0025 0.0185 0.1251
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.1277 0.8617
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0256 0.1637
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0173 0.0428
Onchocerca volvulus 0.0052 0.0616 0.1619
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1482 0.4279
Leishmania major phosphoglycerate kinase B, cytosolic 0.0085 0.1117 0.1222
Trichomonas vaginalis set domain proteins, putative 0.0236 0.3463 1
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0735 0.0804
Loa Loa (eye worm) hypothetical protein 0.0023 0.0154 0.0109
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0256 0.0738
Echinococcus multilocularis regulator of G protein signaling 3 0.0059 0.0725 0.0683
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.019 0.2753 0.272
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0263 0.0226
Brugia malayi jmjC domain containing protein 0.0072 0.0922 0.2948
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0735 0.0804
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0085 0.1117 0.5
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0264 0.0289
Trypanosoma brucei ISWI complex protein 0.0015 0.0038 0.0042
Entamoeba histolytica hypothetical protein 0.0023 0.0154 0.1041
Schistosoma mansoni hypothetical protein 0.0034 0.0328 0.0291
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0059 0.0725 0.069
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0059 0.0725 0.0683
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.1482 0.1443
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0119 0.1651 0.1619
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0173 0.0499
Brugia malayi CXXC zinc finger family protein 0.0033 0.032 0.0922
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0246 0.0202
Schistosoma mansoni regulator of G protein signaling 0.0059 0.0725 0.069
Brugia malayi CHD4 protein 0.0025 0.0184 0.0465
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0093 0.0342
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0505 0.0552
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.3019 0.2987
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0078 0.1009 0.2777
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0256 0.0738
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0019 0.0096 0.0036
Plasmodium falciparum phd finger protein, putative 0.0058 0.0703 0.5958
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0357 0.0313
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0601 0.9138 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0045 0.0505 0.0461
Trypanosoma cruzi ISWI complex protein 0.0015 0.0038 0.0042
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0103 0.1402 0.1534
Plasmodium vivax SET domain protein, putative 0.003 0.0263 0.1978
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0017 0.0066 0.0068
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0031 0.0285 0.0311
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.1482 1
Trichomonas vaginalis chromobox protein, putative 0.0084 0.1101 0.3179
Trypanosoma cruzi ISWI complex protein 0.0015 0.0038 0.0042
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0505 0.0552
Trypanosoma brucei phosphoglycerate kinase 0.0085 0.1117 0.1222
Trypanosoma brucei unspecified product 0.0054 0.0633 0.0693
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0601 0.9138 1
Echinococcus granulosus regulator of G protein signaling 7 0.0059 0.0725 0.0683
Mycobacterium ulcerans phosphoglycerate kinase 0.0085 0.1117 0.0959
Echinococcus multilocularis lysine specific demethylase 5A 0.007 0.0893 0.0851
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0065 0.002
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0045 0.0505 0.1545
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0572 0.0529
Leishmania major hypothetical protein, conserved 0.0019 0.0093 0.0101
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0122 0.0077
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0256 0.1907
Echinococcus granulosus expressed protein 0.0412 0.6198 0.6181
Echinococcus granulosus Regulator of G protein signaling 20 0.0059 0.0725 0.0683
Brugia malayi Importin beta-1 subunit 0.0062 0.0757 0.2393
Onchocerca volvulus 0.0061 0.0748 0.2009
Brugia malayi TAR-binding protein 0.0065 0.0819 0.26
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0045 0.0505 0.4248
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0013 0.0002 0.0003
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0426 0.0466
Entamoeba histolytica hypothetical protein 0.0059 0.0725 0.4895
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.0703 0.066
Brugia malayi ImpB/MucB/SamB family protein 0.0059 0.0718 0.226
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0023 0.0154 0.0109
Treponema pallidum phosphoglycerate kinase 0.0085 0.1117 0.7025
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0154 0.0601
Brugia malayi Bromodomain containing protein 0.0075 0.0961 0.3079
Leishmania major modification methylase-like protein 0.002 0.0107 0.0117
Brugia malayi Associated with TFs and helicases family protein 0.0023 0.0154 0.0366
Brugia malayi A-kinase anchor protein 10, precursor 0.0059 0.0725 0.2287
Echinococcus multilocularis chromobox protein 1 0.0139 0.1956 0.1919
Schistosoma mansoni hypothetical protein 0.0023 0.0154 0.0116
Echinococcus granulosus zinc finger protein 0.0019 0.0104 0.0059
Loa Loa (eye worm) hypothetical protein 0.0038 0.0395 0.0351
Echinococcus granulosus regulator of G protein signaling 3 0.0059 0.0725 0.0683
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0757 0.0828
Schistosoma mansoni regulator of G protein signaling 0.0059 0.0725 0.069
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.002 0.0107 0.0722
Mycobacterium tuberculosis Conserved hypothetical protein 0.0317 0.4719 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0703 0.5194
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0154 0.0116
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0819 0.0783
Trypanosoma brucei DNA polymerase eta, putative 0.0059 0.0718 0.0785
Echinococcus granulosus metabotropic glutamate receptor 2 0.0088 0.1164 0.1123
Onchocerca volvulus 0.0033 0.032 0.0748
Loa Loa (eye worm) hypothetical protein 0.0062 0.0757 0.0715
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0034 0.0324 0.0279
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0154 0.0445
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0657 0.1896
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0735 0.0804
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0025 0.0185 0.1247
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.1265 0.1225
Onchocerca volvulus Alhambra homolog 0.0058 0.0703 0.1876
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0154 0.0445
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0085 0.1115 0.122
Loa Loa (eye worm) hypothetical protein 0.0017 0.0066 0.002
Schistosoma mansoni hypothetical protein 0.0337 0.504 0.5021
Trichomonas vaginalis chromobox protein, putative 0.0084 0.1101 0.3179
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0095 0.0057
Echinococcus granulosus regulator of G protein signaling 7 0.0059 0.0725 0.0683
Echinococcus granulosus Chromobox protein 3 0.0023 0.0154 0.0109
Giardia lamblia DINP protein human, muc B family 0.004 0.0426 0.2202
Brugia malayi Pre-SET motif family protein 0.0207 0.3019 1
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0185 0.0535
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0819 0.0777
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.002 0.0107 0.0456
Schistosoma mansoni z-protein (S1r protein) 0.0059 0.0725 0.069
Loa Loa (eye worm) hypothetical protein 0.0023 0.0154 0.0109
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.0703 0.0667
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0096 0.0371
Loa Loa (eye worm) hypothetical protein 0.0042 0.0461 0.0417
Echinococcus multilocularis snurportin 1 0.0657 1 1
Schistosoma mansoni hypothetical protein 0.0017 0.0066 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0725 0.2095
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0657 1 1
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0085 0.1117 0.3226
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0725 0.2095
Leishmania major DNA polymerase kappa, putative 0.004 0.0426 0.0466
Echinococcus granulosus axis inhibition protein axin 0.0059 0.0725 0.0683
Echinococcus multilocularis jumonji domain containing protein 0.0081 0.1056 0.1015
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0256 0.1637
Plasmodium falciparum heterochromatin protein 1 0.0023 0.0154 0.0601
Schistosoma mansoni zinc finger protein 0.0019 0.0104 0.0066
Loa Loa (eye worm) hypothetical protein 0.0059 0.0725 0.0683
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0725 0.0682
Entamoeba histolytica hypothetical protein 0.0059 0.0725 0.4895
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1277 0.3687
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0819 0.0777
Loa Loa (eye worm) helicase 0.0023 0.0154 0.0109
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1265 0.1231
Trichomonas vaginalis dullard protein, putative 0.0025 0.0185 0.0535
Echinococcus multilocularis GPCR, family 3, C terminal 0.0017 0.0066 0.002
Brugia malayi hypothetical protein 0.0023 0.0154 0.0366
Brugia malayi RNA, U transporter 1 0.0175 0.2518 0.8317
Echinococcus granulosus beta-adrenergic receptor kinase 0.041 0.6165 0.6148
Echinococcus multilocularis dna polymerase eta 0.0059 0.0718 0.0675
Loa Loa (eye worm) hypothetical protein 0.0027 0.0219 0.0174
Loa Loa (eye worm) hypothetical protein 0.0085 0.1117 0.1076
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0085 0.1117 0.1222
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0059 0.0725 0.069
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0034 0.0324 0.0279
Onchocerca volvulus 0.0038 0.0397 0.0976
Brugia malayi 6-phosphofructokinase 0.0108 0.1482 0.4831
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0023 0.0154 0.0831
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0052 0.0616 0.058
Loa Loa (eye worm) hypothetical protein 0.0059 0.0725 0.0683
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0375 0.041
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.002 0.0107 0.0117
Trypanosoma cruzi DNA polymerase eta, putative 0.0059 0.0718 0.0785
Echinococcus multilocularis DNA methyltransferase 2, putative 0.002 0.0107 0.0062
Brugia malayi PXA domain containing protein 0.0059 0.0725 0.2287
Plasmodium falciparum phosphoglycerate kinase 0.0085 0.1117 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0263 0.0219
Echinococcus multilocularis zinc finger protein 0.0019 0.0104 0.0059
Brugia malayi M-phase phosphoprotein, mpp8 0.0023 0.0154 0.0366
Schistosoma mansoni chromobox protein 0.0139 0.1956 0.1925
Onchocerca volvulus Serine\/threonine kinase homolog 0.0095 0.1277 0.3565
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1482 1
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1482 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.1265 0.1231
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0061 0.0745 0.2353
Loa Loa (eye worm) RGS-3 protein 0.0059 0.0725 0.0683
Brugia malayi Heterochromatin protein 1 0.0139 0.1956 0.6424
Echinococcus granulosus phd:f box containing protein 0.0019 0.0093 0.0047
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0088 0.1164 0.1123
Loa Loa (eye worm) hypothetical protein 0.0023 0.0154 0.0109
Brugia malayi regulator of G-protein signaling egl-10 0.0059 0.0725 0.2287
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0657 0.1896
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0256 0.0738
Loa Loa (eye worm) PXA domain-containing protein 0.0059 0.0725 0.0683
Loa Loa (eye worm) hypothetical protein 0.0129 0.1804 0.1766
Echinococcus multilocularis regulator of G protein signaling 3 0.0059 0.0725 0.0683
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0572 0.1772
Schistosoma mansoni regulator of G protein signaling 0.0059 0.0725 0.069
Echinococcus granulosus bloom syndrome protein 0.0024 0.0173 0.0128
Brugia malayi regulator of G-protein signaling rgs-7 0.0059 0.0725 0.2287
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0034 0.0324 0.0287
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0256 0.1907
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0735 0.0804
Schistosoma mansoni jumonji domain containing protein 0.0151 0.2147 0.2117
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0025 0.0185 0.0148
Loa Loa (eye worm) hypothetical protein 0.0019 0.0093 0.0047
Loa Loa (eye worm) hypothetical protein 0.0023 0.0154 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0154 0.0445
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0025 0.0185 0.1247
Echinococcus multilocularis disco interacting protein 2 0.0038 0.0397 0.0353
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0017 0.0066 0.0128
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.015 0.0105
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0426 0.0466
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0093 0.0047
Loa Loa (eye worm) jmjC domain-containing protein 0.0072 0.0922 0.0881
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0185 0.0203
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0045 0.0505 0.4024
Schistosoma mansoni chromobox protein 0.0139 0.1956 0.1925
Brugia malayi jmjC domain containing protein 0.0019 0.0093 0.0158
Plasmodium vivax phosphoglycerate kinase, putative 0.0085 0.1117 1
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.1277 0.1243
Echinococcus multilocularis beta adrenergic receptor kinase 0.041 0.6165 0.6148
Brugia malayi PHD-finger family protein 0.0025 0.0187 0.0475
Schistosoma mansoni phosphoglycerate kinase 0.0085 0.1117 0.1083
Loa Loa (eye worm) hypothetical protein 0.0059 0.0718 0.0675
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0059 0.0725 0.2095
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0059 0.0725 0.069
Entamoeba histolytica Ran family GTPase 0.0045 0.0505 0.3407
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0284 0.422 0.4618
Echinococcus granulosus disco interacting protein 2 0.0038 0.0397 0.0353
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0085 0.1115 0.122
Schistosoma mansoni cpg binding protein 0.0033 0.032 0.0282
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.015 0.0112
Trypanosoma brucei phosphoglycerate kinase 0.0031 0.0285 0.0311
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0093 0.0055
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.1482 1
Brugia malayi jmjC domain containing protein 0.0019 0.0093 0.0158
Leishmania major DNA polymerase eta, putative 0.0036 0.0358 0.0391
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0113 0.0075
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0256 0.1725
Schistosoma mansoni cpg binding protein 0.0035 0.0349 0.0312
Loa Loa (eye worm) hypothetical protein 0.0041 0.0431 0.0388
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0819 0.0783
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0122 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.1009 0.2914
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0819 0.26
Trichomonas vaginalis ran, putative 0.0045 0.0505 0.1458
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0025 0.0184 0.0139
Schistosoma mansoni regulator of G protein signaling 0.0059 0.0725 0.069
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0735 0.0804
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0256 0.0738
Brugia malayi ImpB/MucB/SamB family protein 0.0034 0.0324 0.0936
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0023 0.0154 0.0109
Echinococcus granulosus importin subunit beta 1 0.0062 0.0757 0.0715
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0154 0.0445
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0527 0.049
Brugia malayi Valyl-tRNA synthetase 0.0023 0.0154 0.0366
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0023 0.0154 0.0366
Loa Loa (eye worm) hypothetical protein 0.0023 0.0154 0.0109
Echinococcus multilocularis regulator of G protein signaling 0.0059 0.0725 0.0683
Brugia malayi Phosphoglycerate kinase 0.0085 0.1117 0.3604
Leishmania major phosphoglycerate kinase C, glycosomal 0.0085 0.1117 0.1222
Loa Loa (eye worm) hypothetical protein 0.0061 0.0748 0.0706
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0154 0.0445
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0045 0.0505 0.0552
Loa Loa (eye worm) hypothetical protein 0.0059 0.0725 0.0683
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1277 0.3687
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0129 0.1804 0.1766
Entamoeba histolytica hypothetical protein 0.0023 0.0154 0.1041
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0143 0.0327
Onchocerca volvulus 0.0023 0.0154 0.0261
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0085 0.1115 0.122
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0922 0.0887
Trypanosoma brucei DNA polymerase IV, putative 0.0054 0.0633 0.0693
Loa Loa (eye worm) hypothetical protein 0.0024 0.0181 0.0136
Plasmodium vivax heterochromatin protein 1, putative 0.0023 0.0154 0.0955
Echinococcus multilocularis Chromobox protein 3 0.0023 0.0154 0.0109
Schistosoma mansoni metabotropic glutamate receptor 0.0088 0.1164 0.113
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0375 0.041
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0819 0.0783
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0093 0.0047
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0093 0.0101
Brugia malayi polk-prov protein 0.0037 0.0375 0.1107
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0025 0.0185 0.0203
Toxoplasma gondii DNA methyltransferase 2, putative 0.002 0.0107 0.0456
Echinococcus multilocularis Regulator of G protein signaling 20 0.0059 0.0725 0.0683
Toxoplasma gondii hypothetical protein 0.0084 0.111 0.8427
Brugia malayi PHD-finger family protein 0.0058 0.0703 0.2211
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0735 0.0804
Trichomonas vaginalis dullard protein, putative 0.0025 0.0185 0.0535
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0185 0.0535
Schistosoma mansoni hypothetical protein 0.0657 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0264 0.0289
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.1265 0.1225
Onchocerca volvulus 0.0236 0.3463 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.1277 0.1397
Echinococcus granulosus metabotropic glutamate receptor 5 0.0129 0.1804 0.1766
Trichomonas vaginalis importin beta-1, putative 0.005 0.0576 0.1664
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0093 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.054 0.1558
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.002 0.0107 0.0069
Schistosoma mansoni hypothetical protein 0.0337 0.504 0.5021
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0065 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0735 0.0804
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0093 0.0047
Echinococcus granulosus dna polymerase kappa 0.006 0.0735 0.0692
Plasmodium vivax JmjC domain containing protein 0.0019 0.0093 0.0376
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0065 0.0027
Loa Loa (eye worm) hypothetical protein 0.007 0.0895 0.0853
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0154 0.0445
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.015 0.0105
Schistosoma mansoni ran 0.0045 0.0505 0.0468
Schistosoma mansoni hypothetical protein 0.0019 0.0096 0.0058
Schistosoma mansoni axis inhibition protein axin 0.0059 0.0725 0.069
Echinococcus granulosus DNA methyltransferase 2, putative 0.002 0.0107 0.0062
Loa Loa (eye worm) hypothetical protein 0.0037 0.0375 0.0331
Echinococcus granulosus regulator of G protein signaling 3 0.0059 0.0725 0.0683
Loa Loa (eye worm) RNA binding protein 0.0065 0.0819 0.0777
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0154 0.0445
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0154 0.1041
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.0576 0.1664
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0075 0.0029
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0328 0.0952
Brugia malayi AF-10 protein 0.0019 0.0096 0.0171
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0703 0.5194
Brugia malayi Disco-interacting protein 2 homolog 0.0038 0.0397 0.1183
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0093 0.0055
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0256 0.1637
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0093 0.0047
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0093 0.0047
Leishmania major GTP-binding protein, putative 0.0045 0.0505 0.0552
Schistosoma mansoni regulator of G protein signaling 0.0059 0.0725 0.069
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0093 0.0047
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0095 0.1277 0.1237
Schistosoma mansoni terminal deoxycytidyl transferase 0.0034 0.0324 0.0287
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0173 0.0499
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0038 0.0397 0.036
Schistosoma mansoni chromobox protein 0.0023 0.0154 0.0116
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0025 0.0185 0.014
Trypanosoma brucei unspecified product 0.0023 0.0162 0.0177
Trichomonas vaginalis Importin beta-1 subunit, putative 0.005 0.0576 0.1664
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0185 0.0535

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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