Detailed information for compound 1175581

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1401.38 | Formula: C60H90Na2O32S
  • H donors: 13 H acceptors: 19 LogP: -3.26 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC[C@H]1O[C@@H](O[C@@H]2[C@@H](C)O[C@H]([C@@H]([C@H]2O)O)O[C@H]2[C@@H](OC[C@H]([C@@H]2O)O[C@@H]2O[C@H](COS(=O)(=O)[O-])[C@H]([C@@H]([C@H]2O)O)O)O[C@H]2CC[C@]3([C@H](C2(C)C)CC(=O)C2=C3CC[C@]34[C@@]2(C)CC[C@@H]4[C@](OC3=O)(C)CC(=O)CC(C)C)C)[C@@H]([C@H]([C@@H]1O)O[C@@H]1O[C@H](C(=O)[O-])[C@H]([C@@H]([C@H]1O)OC)O)O.[Na+].[Na+]
  • InChi: 1S/C60H92O32S.2Na/c1-22(2)16-24(62)18-59(8)30-11-14-58(7)33-25(10-15-60(30,58)55(76)92-59)57(6)13-12-32(56(4,5)31(57)17-26(33)63)87-54-48(36(66)28(20-81-54)85-51-39(69)37(67)34(64)29(86-51)21-82-93(77,78)79)91-50-40(70)38(68)44(23(3)83-50)88-52-43(73)46(35(65)27(19-61)84-52)89-53-42(72)45(80-9)41(71)47(90-53)49(74)75;;/h22-23,27-32,34-48,50-54,61,64-73H,10-21H2,1-9H3,(H,74,75)(H,77,78,79);;/q;2*+1/p-2/t23-,27-,28-,29-,30-,31+,32+,34-,35-,36+,37+,38-,39-,40-,41+,42-,43-,44-,45+,46+,47+,48-,50+,51-,52+,53-,54+,57-,58+,59+,60-;;/m1../s1
  • InChiKey: KRXSSGWGHZSDGT-IJWGQMDZSA-L  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0002 0.0009
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0051 0.0051
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.1583 0.5758 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0264 0.0895 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0006 0.0006
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1697 0.6178 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.0006 0.5
Schistosoma mansoni hypothetical protein 0.0658 0.2347 1
Loa Loa (eye worm) hypothetical protein 0.0542 0.192 0.192
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0076 0.0132
Leishmania major importin beta-1 subunit, putative 0.0023 0.0008 0.0013
Echinococcus multilocularis carnitine O palmitoyltransferase 2 0.0577 0.2051 0.332
Schistosoma mansoni hypothetical protein 0.0074 0.0197 0.0841
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0008 0.0044
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.008 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0002 0.0009
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0034 0.2186
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0107 0.032 0.1363
Loa Loa (eye worm) hypothetical protein 0.0348 0.1206 0.1206
Echinococcus granulosus carnitine O palmitoyltransferase 1 liver 0.1583 0.5758 1
Trypanosoma cruzi carnitine/choline acetyltransferase, putative 0.0348 0.1206 0.2095
Loa Loa (eye worm) choline O-acetyltransferase 0.0348 0.1206 0.1206
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0428 0.1501 0.2606
Brugia malayi Choline O-acetyltransferase 0.0348 0.1206 0.1206
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.1583 0.5758 1
Echinococcus granulosus choline O acetyltransferase 0.0348 0.1206 0.2095
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0076 0.0076
Schistosoma mansoni survival motor neuron protein 0.0111 0.0331 0.1411
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0006 0.001
Loa Loa (eye worm) mbt repeat family protein 0.0107 0.032 0.032
Toxoplasma gondii ABC1 family protein 0.0041 0.0076 0.4849
Loa Loa (eye worm) hypothetical protein 0.0041 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0028 0.0027 0.0027
Loa Loa (eye worm) carnitine O-palmitoyltransferase I isoform 0.0348 0.1206 0.1206
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0006 0.0011
Echinococcus granulosus importin subunit beta 1 0.0028 0.0027 0.0047
Schistosoma mansoni hypothetical protein 0.0039 0.0068 0.0288
Mycobacterium leprae Probable lipase LipE 0.0041 0.0076 1
Schistosoma mansoni ap endonuclease 0.0022 0.0006 0.0027
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0008 0.0013
Leishmania major DNA polymerase eta, putative 0.0034 0.0051 0.0088
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0002 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0002 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.01 0.0428
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0076 0.0132
Trypanosoma brucei DNA polymerase eta, putative 0.0049 0.0105 0.051
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0002 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0002 0.0009
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0006 0.0035
Schistosoma mansoni inositol monophosphatase 0.0042 0.008 0.0341
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0008 0.0044
Echinococcus multilocularis carnitine O palmitoyltransferase 1, liver 0.1583 0.5758 0.932
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0027 0.0133
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0002 0.0009
Brugia malayi hypothetical protein 0.0305 0.1047 0.1047
Echinococcus multilocularis geminin 0.0164 0.053 0.0857
Echinococcus granulosus snurportin 1 0.0299 0.1026 0.1782
Schistosoma mansoni DNA polymerase eta 0.0049 0.0105 0.0445
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0076 0.0429
Brugia malayi hypothetical protein 0.0542 0.192 0.192
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0051 0.0088
Echinococcus multilocularis choline O acetyltransferase 0.0348 0.1206 0.1952
Trichomonas vaginalis esterase, putative 0.0041 0.0076 0.0429
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.0164 0.053 0.2256
Trypanosoma cruzi hypothetical protein, conserved 0.0348 0.1206 0.2095
Schistosoma mansoni hypothetical protein 0.0034 0.0051 0.0215
Loa Loa (eye worm) inositol-1 0.0042 0.008 0.008
Trichomonas vaginalis set domain proteins, putative 0.0501 0.177 1
Loa Loa (eye worm) transcription factor SMAD2 0.0132 0.041 0.041
Trypanosoma cruzi choline/carnitine O-acetyltransferase, putative 0.0348 0.1206 0.2095
Echinococcus multilocularis snurportin 1 0.0299 0.1026 0.1661
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0002 0.0008
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0076 0.0123
Trypanosoma cruzi hypothetical protein, conserved 0.0348 0.1206 0.2095
Leishmania major hypothetical protein, conserved 0.003 0.0034 0.0059
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0076 0.0324
Brugia malayi mbt repeat family protein 0.0107 0.032 0.032
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0006 0.0031
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0034 0.0059
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0006 0.0784
Brugia malayi Choline O-acetyltransferase 0.0348 0.1206 0.1206
Leishmania major DNA polymerase kappa, putative 0.0021 0.0002 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0157 0.0668
Brugia malayi Inositol-1 0.0042 0.008 0.008
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0076 1
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.008 0.0129
Echinococcus granulosus carnitine O palmitoyltransferase 2 0.0577 0.2051 0.3562
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0002 0.0008
Onchocerca volvulus 0.0348 0.1206 0.6669
Echinococcus multilocularis polycomb protein SCMH1 0.0107 0.032 0.0518
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0076 0.083
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.008 0.0451
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0006 0.0011
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.01 0.01
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0122 0.0375 0.0607
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0002 0.0002
Trypanosoma cruzi carnitine O-acetyltransferase, putative 0.0348 0.1206 0.2095
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0006 0.0035
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0042 0.008 1
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0107 0.032 0.1439
Schistosoma mansoni hypothetical protein 0.0111 0.0331 0.1411
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0157 0.0668
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0034
Onchocerca volvulus 0.0348 0.1206 0.6669
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0076 0.083
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0034 0.0059
Leishmania major choline/Carnitine o-acyltransferase-like protein 0.1583 0.5758 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0051 0.0088
Entamoeba histolytica hypothetical protein 0.0039 0.0068 0.8455
Echinococcus granulosus survival motor neuron protein 1 0.0542 0.192 0.3335
Plasmodium vivax importin-beta 2, putative 0.0028 0.0027 0.1739
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0122 0.0375 0.0375
Onchocerca volvulus 0.0348 0.1206 0.6669
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0157 0.0668
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.008 0.0451
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0006 0.0011
Schistosoma mansoni choline o-acyltransferase 0.0348 0.1206 0.5138
Schistosoma mansoni importin beta-1 0.0028 0.0027 0.0116
Loa Loa (eye worm) hypothetical protein 0.0109 0.0324 0.0324
Echinococcus multilocularis SAM and MBT domain containing protein 0.0107 0.032 0.0518
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0027 0.1739
Brugia malayi ImpB/MucB/SamB family protein 0.0049 0.0105 0.0105
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0157 0.0272
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0068 0.0117
Onchocerca volvulus 0.0111 0.0331 0.1506
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0348 0.1206 0.2095
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0051 0.0082
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.0324 0.0324
Onchocerca volvulus 0.0348 0.1206 0.6669
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.008 0.0139
Brugia malayi beta-lactamase family protein 0.0041 0.0076 0.0076
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0076 0.4849
Brugia malayi Importin beta-1 subunit 0.0028 0.0027 0.0027
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0006 0.0011
Schistosoma mansoni hypothetical protein 0.0034 0.0051 0.0215
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.008 0.0139
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.008 0.039
Echinococcus granulosus histone acetyltransferase MYST2 0.0122 0.0375 0.0651
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.01 0.01
Schistosoma mansoni hypothetical protein 0.0034 0.0051 0.0215
Echinococcus granulosus polycomb protein SCMH1 0.0107 0.032 0.0556
Brugia malayi mbt repeat family protein 0.0107 0.032 0.032
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0008 0.0044
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0111 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0041 0.0076 0.0076
Trypanosoma cruzi DNA polymerase eta, putative 0.0049 0.0105 0.0182
Loa Loa (eye worm) beta-lactamase 0.0041 0.0076 0.0076
Echinococcus multilocularis GPCR, family 2 0.0034 0.0051 0.0082
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0002 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0002 0.0009
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0002 0.0003
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0051 0.0051
Echinococcus granulosus dna polymerase kappa 0.0021 0.0002 0.0003
Echinococcus multilocularis dna polymerase eta 0.0049 0.0105 0.0169
Echinococcus granulosus geminin 0.0164 0.053 0.092
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0197 0.0197
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0076 0.0324
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0006 0.1829
Onchocerca volvulus 0.0107 0.032 0.1439
Echinococcus granulosus SAM and MBT domain containing protein 0.0107 0.032 0.0556
Mycobacterium ulcerans lipase LipD 0.0041 0.0076 0.9497
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.1026 0.1026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.01 0.0163
Trypanosoma brucei carnitine O-palmitoyltransferase II, putative 0.0348 0.1206 0.588
Onchocerca volvulus 0.0501 0.177 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0002 0.0009
Echinococcus multilocularis survival motor neuron protein 1 0.0542 0.192 0.3108
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0027 0.0133
Trypanosoma cruzi carnitine O-palmitoyltransferase II, putative 0.0577 0.2051 0.3562
Entamoeba histolytica hypothetical protein 0.0039 0.0068 0.8455
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.008 1
Trypanosoma brucei unspecified product 0.0021 0.0002 0.0009
Schistosoma mansoni sex comb on midleg homolog 0.0107 0.032 0.1363
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0428 0.1501 0.2429
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0076 0.083
Loa Loa (eye worm) hypothetical protein 0.0041 0.0076 0.0076
Brugia malayi beta-lactamase 0.0041 0.0076 0.0076
Trypanosoma brucei carnitine O-palmitoyltransferase, putative 0.0348 0.1206 0.588
Loa Loa (eye worm) hypothetical protein 0.0034 0.0051 0.0051
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0076 0.0132
Entamoeba histolytica hypothetical protein 0.0039 0.0068 0.8455
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0051 0.0051
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0002 0.023
Giardia lamblia DINP protein human, muc B family 0.0021 0.0002 0.2929
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0076 0.0371
Mycobacterium ulcerans hypothetical protein 0.0041 0.0076 0.9497
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.01 0.0428
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0042 0.008 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0051 0.0088
Schistosoma mansoni hypothetical protein 0.0164 0.053 0.2256
Brugia malayi Pre-SET motif family protein 0.044 0.1546 0.1546
Leishmania major carnitine/choline acetyltransferase, putative 0.0348 0.1206 0.2095
Brugia malayi MH2 domain containing protein 0.0132 0.041 0.041
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0002 0.0002
Brugia malayi hypothetical protein 0.003 0.0034 0.0034
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.044 0.1546 0.1546
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0002 0.0003
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0034 0.0167
Loa Loa (eye worm) hypothetical protein 0.2735 1 1
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0076 0.9497
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0006 0.0006
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.0324 0.0324
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0148 0.0257
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0034 1
Leishmania major DNA polymerase eta, putative 0.0049 0.0105 0.0182
Mycobacterium tuberculosis Conserved protein 0.0041 0.0076 0.083
Echinococcus multilocularis histone acetyltransferase MYST2 0.0122 0.0375 0.0607
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0002 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0348 0.1206 0.2095
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0002 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.01 0.0428
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0068 0.0109
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0034 1
Leishmania major hypothetical protein, conserved 0.0041 0.0076 0.0132
Loa Loa (eye worm) hypothetical protein 0.0049 0.0105 0.0105
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0027 0.0044
Loa Loa (eye worm) MBCTL1 0.0122 0.0375 0.0375
Plasmodium falciparum importin beta, putative 0.0028 0.0027 0.7957
Loa Loa (eye worm) MH2 domain-containing protein 0.0132 0.041 0.041
Echinococcus granulosus dna polymerase eta 0.0049 0.0105 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0002 0.0009
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0122 0.0375 0.0651
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0076 0.0429
Schistosoma mansoni ap endonuclease 0.0022 0.0006 0.0027
Loa Loa (eye worm) hypothetical protein 0.0305 0.1047 0.1047
Entamoeba histolytica hypothetical protein 0.0039 0.0068 0.8455
Trypanosoma cruzi carnitine/choline acetyltransferase, putative 0.0348 0.1206 0.2095
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0076 0.0429
Plasmodium vivax SET domain protein, putative 0.0063 0.0157 1
Trypanosoma brucei hypothetical protein, conserved 0.0348 0.1206 0.588
Loa Loa (eye worm) hypothetical protein 0.0063 0.0157 0.0157
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0076 0.0429
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0006 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0076 0.0429
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0157 0.0668
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.0006 0.005
Loa Loa (eye worm) hypothetical protein 0.0122 0.0375 0.0375
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0051 0.0082
Schistosoma mansoni inositol monophosphatase 0.0042 0.008 0.0341
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.008 0.0451
Loa Loa (eye worm) hypothetical protein 0.0041 0.0076 0.0076
Schistosoma mansoni myelin transcription factor 1 myt1 0.0122 0.0375 0.1596
Loa Loa (eye worm) hypothetical protein 0.0041 0.0076 0.0076
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.008 0.0139
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0002 0.001
Loa Loa (eye worm) hypothetical protein 0.0074 0.0197 0.0197
Brugia malayi RNA, U transporter 1 0.008 0.0218 0.0218
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0034 0.2186
Schistosoma mansoni hypothetical protein 0.0034 0.0051 0.0215
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0068 0.0288
Trypanosoma brucei carnitine O-acetyltransferase, putative 0.0348 0.1206 0.588
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0051 0.3247
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.0324 0.0324
Echinococcus granulosus GPCR family 2 0.0034 0.0051 0.0088
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0076 0.9497
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0002 0.0003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0157 0.0254
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0348 0.1206 0.1206
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0076 0.0076
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0076 0.083
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.01 0.0174
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0577 0.2051 0.2051
Brugia malayi beta-lactamase family protein 0.0041 0.0076 0.0076
Mycobacterium ulcerans beta-lactamase 0.0041 0.0076 0.9497
Entamoeba histolytica hypothetical protein 0.0023 0.0008 0.0967
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.0006 0.0567
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.01 0.0174
Trypanosoma brucei carnitine O-palmitoyltransferase II, putative 0.0577 0.2051 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0076 0.083
Brugia malayi Pre-SET motif family protein 0.0063 0.0157 0.0157
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.008 0.51
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0041 0.0076 0.0076
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0157 1
Trypanosoma cruzi hypothetical protein, conserved 0.0348 0.1206 0.2095
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.01 0.0163
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0002 0.0009
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0076 0.083
Onchocerca volvulus 0.0063 0.0157 0.0476
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0002 0.0003
Onchocerca volvulus 0.0305 0.1047 0.5729
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0002 0.0009
Mycobacterium tuberculosis Conserved protein 0.0041 0.0076 0.083
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0064 0.0691
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0076 0.083
Toxoplasma gondii exonuclease III APE 0.0022 0.0006 0.04
Schistosoma mansoni sex comb on midleg homolog 0.0107 0.032 0.1363
Trypanosoma cruzi hypothetical protein, conserved 0.0348 0.1206 0.2095
Loa Loa (eye worm) hypothetical protein 0.0107 0.032 0.032
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0002 0.0009
Leishmania major carnitine palmitoyltransferase-like protein 0.0577 0.2051 0.3562
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0157 0.0254
Schistosoma mansoni choline o-acyltransferase 0.0348 0.1206 0.5138
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0006 0.04
Schistosoma mansoni hypothetical protein 0.0299 0.1026 0.4372
Loa Loa (eye worm) choline/Carnitine O-acyltransferase 0.0577 0.2051 0.2051
Brugia malayi hypothetical protein 0.0039 0.0068 0.0068
Mycobacterium tuberculosis Conserved protein 0.0041 0.0076 0.083

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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