Detailed information for compound 1200569

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 449.974 | Formula: C22H32ClN5O3
  • H donors: 1 H acceptors: 3 LogP: 3.55 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2nc(nc(c2cc1OC)N)N1CCC(CC1)C(=O)N1CCCCCC1.Cl
  • InChi: 1S/C22H31N5O3.ClH/c1-29-18-13-16-17(14-19(18)30-2)24-22(25-20(16)23)27-11-7-15(8-12-27)21(28)26-9-5-3-4-6-10-26;/h13-15H,3-12H2,1-2H3,(H2,23,24,25);1H
  • InChiKey: IPIOFGYLENXRIB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0109 0.011
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0136 0.0447 0.7914
Echinococcus granulosus tumor protein p63 0.0355 0.1294 0.513
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0109 0.0534
Brugia malayi hypothetical protein 0.002 0.0002 0.0002
Plasmodium vivax pyruvate kinase, putative 0.0065 0.0175 0.31
Schistosoma mansoni dishevelled 0.002 0.0002 0.0008
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0109 0.1507
Echinococcus multilocularis sphingomyelin synthase protein 1 0.0136 0.0447 0.0447
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0091 0.0274 0.3609
Trypanosoma brucei glycosyl hydrolase-like protein 0.0027 0.0029 0.0402
Loa Loa (eye worm) ShTK domain-containing protein 0.009 0.0272 0.0273
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0136 0.0447 0.2184
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.26 0.9951 1
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.0565 0.276
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0016 0.0064
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0136 0.0447 0.0449
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0207 0.1009
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0043 0.0043
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0136 0.0447 0.6165
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0136 0.0447 0.2184
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0897 0.4381
Loa Loa (eye worm) hypothetical protein 0.0136 0.0447 0.0449
Loa Loa (eye worm) hypothetical protein 0.0027 0.0029 0.0029
Loa Loa (eye worm) DIX domain-containing protein 0.002 0.0002 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0029 0.0142
Schistosoma mansoni inositol transporter 0.004 0.0077 0.0305
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0043 0.0043
Brugia malayi glutathione reductase 0.004 0.0077 0.0078
Loa Loa (eye worm) hypothetical protein 0.0412 0.1514 0.1521
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0079 0.0228 0.0903
Echinococcus granulosus survival motor neuron protein 1 0.0249 0.0883 0.3499
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0252 0.0897 0.0901
Treponema pallidum phosphoglycerate kinase 0.0166 0.0565 1
Brugia malayi hypothetical protein 0.0108 0.0341 0.0342
Brugia malayi nuclear receptor NHR-88 0.0031 0.0043 0.0043
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0043 0.0171
Echinococcus multilocularis pyruvate kinase 0.0051 0.0122 0.0122
Schistosoma mansoni hypothetical protein 0.0084 0.0249 0.0986
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0109 0.0534
Echinococcus granulosus expressed conserved protein 0.0097 0.0299 0.1185
Brugia malayi glutaminase DH11.1 0.055 0.2047 0.2057
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0043 0.0043
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0029 0.0402
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0002 0.0002
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0016 0.0079
Echinococcus granulosus geminin 0.0175 0.06 0.238
Loa Loa (eye worm) hypothetical protein 0.26 0.9951 1
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0136 0.0447 0.6165
Brugia malayi Pre-SET motif family protein 0.0031 0.0045 0.0045
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.002 0.0002 0.0008
Toxoplasma gondii pyruvate kinase PyK1 0.0065 0.0175 0.31
Loa Loa (eye worm) hypothetical protein 0.0054 0.0134 0.0134
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.0883 0.0887
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0136 0.0447 0.6165
Echinococcus granulosus pyruvate kinase 0.0065 0.0175 0.0694
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0279 0.0281
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0065 0.0175 0.31
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0043 0.0043
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0043 0.0043
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0166 0.0565 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0043 0.0171
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0043 0.0272
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0043 0.0171
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0029 0.0142
Plasmodium falciparum thioredoxin reductase 0.004 0.0077 0.1367
Loa Loa (eye worm) hypothetical protein 0.0136 0.0447 0.0449
Onchocerca volvulus 0.0052 0.0124 0.0809
Brugia malayi Thioredoxin reductase 0.004 0.0077 0.0078
Loa Loa (eye worm) hypothetical protein 0.0249 0.0883 0.0887
Loa Loa (eye worm) hypothetical protein 0.0045 0.0099 0.01
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0002 0.0008
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0073 0.0207 0.3656
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0095 0.0095
Brugia malayi Niemann-Pick C1 protein precursor 0.0104 0.0323 0.0325
Loa Loa (eye worm) glutathione reductase 0.004 0.0077 0.0078
Onchocerca volvulus Serine\/threonine kinase homolog 0.0113 0.0359 0.2359
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0207 0.1009
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 3 0.0136 0.0447 0.0449
Schistosoma mansoni hypothetical protein 0.0175 0.06 0.238
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.004 0.0077 0.0077
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0043 0.0171
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0043
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0279 0.1107
Echinococcus multilocularis solute carrier family 5 0.004 0.0077 0.0077
Loa Loa (eye worm) latrophilin receptor protein 2 0.0084 0.0249 0.025
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0043 0.0043
Trypanosoma brucei pyruvate kinase 1, putative 0.0065 0.0175 0.2415
Echinococcus granulosus sphingomyelin synthase protein 1 0.0136 0.0447 0.1773
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0279 0.0279
Echinococcus multilocularis pyruvate kinase 0.0033 0.0053 0.0053
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0095 0.0096
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0073 0.0207 0.1009
Brugia malayi Common central domain of tyrosinase family protein 0.009 0.0272 0.0273
Entamoeba histolytica hypothetical protein 0.0136 0.0447 0.7914
Loa Loa (eye worm) hypothetical protein 0.0266 0.095 0.0955
Loa Loa (eye worm) hypothetical protein 0.0104 0.0323 0.0325
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0043 0.0043
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0084 0.0249 0.0249
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.004 0.016
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0027 0.0029 0.0179
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0412 0.1514 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0084 0.0249 0.0249
Schistosoma mansoni transcription factor LCR-F1 0.0108 0.0341 0.1351
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0725 1
Plasmodium vivax phosphoglycerate kinase, putative 0.0166 0.0565 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.033 0.1198 0.1204
Loa Loa (eye worm) hypothetical protein 0.036 0.1312 0.1318
Echinococcus granulosus sodium:myo inositol cotransporter 0.004 0.0077 0.0305
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0016 0.0079
Entamoeba histolytica hypothetical protein 0.0108 0.0341 0.6031
Leishmania major trypanothione reductase 0.004 0.0077 0.1065
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0359 0.1752
Brugia malayi hypothetical protein 0.0249 0.0883 0.0887
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0043 0.0171
Brugia malayi Sphingomyelin synthase-related 1 0.0136 0.0447 0.0449
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0113 0.0359 0.1422
Echinococcus granulosus pyruvate kinase 0.0065 0.0175 0.0694
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0207 0.2848
Trichomonas vaginalis conserved hypothetical protein 0.0136 0.0447 0.2184
Plasmodium vivax thioredoxin reductase, putative 0.004 0.0077 0.1367
Echinococcus multilocularis lysosomal alpha glucosidase 0.033 0.1198 0.1198
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0124 0.0493
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0016 0.0222
Brugia malayi N-terminal motif family protein 0.0412 0.1514 0.1521
Schistosoma mansoni sodium/solute symporter 0.004 0.0077 0.0305
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0061 0.0159 0.2195
Brugia malayi CHE-14 protein 0.0044 0.0095 0.0096
Schistosoma mansoni hypothetical protein 0.0084 0.0249 0.0986
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0279 0.1107
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0279 0.0279
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0043 0.0171
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0043 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0359 0.1752
Loa Loa (eye worm) hypothetical protein 0.009 0.0272 0.0273
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0043 0.0171
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0043 0.0043
Schistosoma mansoni patched 1 0.0044 0.0095 0.0377
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0043
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0062 0.0305
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.009 0.0272 0.0273
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0043
Trypanosoma brucei ceramide phosphorylethanolamine synthase 0.0136 0.0447 0.6165
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0359 0.1752
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0091 0.0274 0.4845
Toxoplasma gondii aldehyde dehydrogenase 0.0072 0.0203 0.3599
Onchocerca volvulus Pyruvate kinase homolog 0.0065 0.0175 0.1145
Trypanosoma brucei phosphoglycerate kinase, putative 0.0061 0.0159 0.2195
Trypanosoma cruzi polo-like protein kinase, putative 0.0113 0.0359 0.4945
Echinococcus multilocularis high affinity choline transporter 1 0.036 0.1312 0.1312
Leishmania major phosphoglycerate kinase C, glycosomal 0.0166 0.0565 0.779
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0166 0.0565 0.276
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0016 0.0222
Trypanosoma cruzi pyruvate kinase 2, putative 0.0065 0.0175 0.2415
Schistosoma mansoni pyruvate kinase 0.0065 0.0175 0.0694
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0029 0.0142
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0562 0.2746
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.0565 0.779
Toxoplasma gondii pyruvate kinase PyKII 0.0033 0.0053 0.0935
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0136 0.0447 0.6165
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0113 0.0359 0.0359
Echinococcus multilocularis segment polarity protein dishevelled 0.002 0.0002 0.0002
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0105 0.0329 0.1305
Trypanosoma brucei polo-like protein kinase 0.0113 0.0359 0.4945
Loa Loa (eye worm) hypothetical protein 0.0084 0.0249 0.025
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0562 0.2746
Echinococcus multilocularis segment polarity protein dishevelled 0.002 0.0002 0.0002
Schistosoma mansoni alpha-glucosidase 0.0284 0.1021 0.4046
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.009 0.0272 0.0273
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0045
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0252 0.0897 0.0901
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0062 0.1104
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0029 0.0142
Leishmania major alpha glucosidase II subunit, putative 0.0073 0.0207 0.2848
Echinococcus multilocularis lysosomal alpha glucosidase 0.033 0.1198 0.1198
Schistosoma mansoni hypothetical protein 0.0175 0.06 0.238
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0109 0.1507
Brugia malayi Latrophilin receptor protein 2 0.0084 0.0249 0.025
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0043 0.0171
Schistosoma mansoni hypothetical protein 0.0182 0.0626 0.248
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.004 0.0077 0.1367
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0077 0.1065
Schistosoma mansoni kinase 0.0057 0.0145 0.0574
Giardia lamblia Pyruvate kinase 0.0065 0.0175 0.31
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.002 0.0002 0.0002
Echinococcus granulosus high affinity choline transporter 1 0.036 0.1312 0.5199
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0045 0.0792
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0029 0.0142
Schistosoma mansoni hypothetical protein 0.0043 0.0089 0.0353
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0043 0.0043
Schistosoma mansoni alpha glucosidase 0.0073 0.0207 0.0819
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0073 0.0207 0.0208
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0109 0.1507
Echinococcus granulosus pyruvate kinase 0.0033 0.0053 0.0209
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0029 0.0029
Schistosoma mansoni dishevelled 0.002 0.0002 0.0008
Brugia malayi Phosphoglycerate kinase 0.0166 0.0565 0.0568
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0079 0.0228 0.3139
Brugia malayi MH2 domain containing protein 0.0249 0.0883 0.0887
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0029 0.0402
Schistosoma mansoni coup transcription factor 0.0031 0.0043 0.0171
Echinococcus granulosus neutral alpha glucosidase AB 0.0073 0.0207 0.0819
Loa Loa (eye worm) hypothetical protein 0.0052 0.0124 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0043 0.0043
Entamoeba histolytica hypothetical protein 0.0136 0.0447 0.7914
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0359 0.1752
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0109 0.0534
Schistosoma mansoni inositol transporter 0.004 0.0077 0.0305
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0043 0.0171
Echinococcus multilocularis sodium:myo inositol cotransporter 0.004 0.0077 0.0077
Mycobacterium ulcerans hypothetical protein 0.0024 0.0016 0.0079
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0109 0.0534
Chlamydia trachomatis phosphoglycerate kinase 0.0166 0.0565 1
Echinococcus granulosus Niemann Pick C1 protein 0.0148 0.0494 0.196
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0207 0.1009
Echinococcus granulosus GPCR family 2 0.0084 0.0249 0.0986
Schistosoma mansoni hypothetical protein 0.0043 0.0089 0.0353
Echinococcus multilocularis tumor protein p63 0.0355 0.1294 0.1294
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0055 0.097
Echinococcus multilocularis protein dispatched 1 0.0051 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0048 0.0109 0.011
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0109 0.1934
Echinococcus multilocularis pyruvate kinase 0.0065 0.0175 0.0175
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0119 0.012
Trypanosoma brucei inositol phosphorylceramide synthase 0.0136 0.0447 0.6165
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0113 0.0359 0.036
Brugia malayi Calcitonin receptor-like protein seb-1 0.0266 0.095 0.0955
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0043 0.0043
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0159 0.2195
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0136 0.0447 0.7914
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0043 0.0171
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0109 0.1934
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0139 0.0679
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0562 0.2746
Echinococcus granulosus pyruvate kinase 0.0033 0.0053 0.0209
Echinococcus multilocularis Niemann Pick C1 protein 0.0148 0.0494 0.0494
Trichomonas vaginalis maltase-glucoamylase, putative 0.0073 0.0207 0.1009
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.01 0.01
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0043 0.0043
Schistosoma mansoni aldehyde dehydrogenase 0.0072 0.0203 0.0806
Echinococcus multilocularis protein patched 0.0044 0.0095 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0043 0.0043
Echinococcus multilocularis geminin 0.0175 0.06 0.06
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0279 0.0281
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0016 0.0285
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0029 0.0142
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0109 0.0534
Loa Loa (eye worm) tyrosinase 1 0.009 0.0272 0.0273
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0266 0.095 0.0955
Entamoeba histolytica hypothetical protein 0.0136 0.0447 0.7914
Brugia malayi ShTK domain containing protein 0.009 0.0272 0.0273
Echinococcus granulosus phosphoglycerate kinase 1 0.0166 0.0565 0.224
Loa Loa (eye worm) hypothetical protein 0.0048 0.0109 0.011
Schistosoma mansoni spingomyelin synthetase-related 0.0136 0.0447 0.1773
Entamoeba histolytica phosphoglycerate kinase, putative 0.0166 0.0565 1
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.004 0.0077 0.0305
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.0562 0.3706
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0109 0.0534
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0182 0.0626 0.0629
Echinococcus granulosus pyruvate kinase 0.0033 0.0053 0.0209
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0136 0.0447 0.2184
Mycobacterium ulcerans hypothetical protein 0.0048 0.0109 0.0534
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0043 0.0043
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0043 0.0171
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0095 0.0377
Trypanosoma cruzi pyruvate kinase 2, putative 0.0065 0.0175 0.2415
Giardia lamblia Pyruvate kinase 0.0033 0.0053 0.0935
Giardia lamblia Phosphoglycerate kinase 0.0166 0.0565 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0207 0.1009
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0073 0.0207 0.1009
Loa Loa (eye worm) hypothetical protein 0.0036 0.0062 0.0063
Mycobacterium ulcerans pyruvate kinase 0.0065 0.0175 0.0856
Echinococcus multilocularis pyruvate kinase 0.0065 0.0175 0.0175
Loa Loa (eye worm) pyruvate kinase 0.0065 0.0175 0.0176
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.002 0.0002 0.0002
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0043 0.0043
Schistosoma mansoni tyrosinase precursor 0.009 0.0272 0.1077
Mycobacterium leprae Probable pyruvate kinase PykA 0.0065 0.0175 0.1446
Schistosoma mansoni aldehyde dehydrogenase 0.0072 0.0203 0.0806
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0043 0.0171
Loa Loa (eye worm) hypothetical protein 0.0166 0.0565 0.0568
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0104 0.0323 0.5718
Echinococcus granulosus transcription factor Dp 1 0.0046 0.01 0.0395
Trichomonas vaginalis set domain proteins, putative 0.0249 0.0883 0.4315
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0072 0.0203 0.0806
Leishmania major phosphoglycerate kinase B, cytosolic 0.0166 0.0565 0.779
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0079 0.0228 0.3139
Giardia lamblia Kinase, PLK 0.0113 0.0359 0.6347
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0359 0.1752
Loa Loa (eye worm) thioredoxin reductase 0.004 0.0077 0.0078
Schistosoma mansoni hypothetical protein 0.0108 0.0341 0.1351
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0002 0.0002
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0079 0.0228 0.0228
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0073 0.0207 0.3656
Onchocerca volvulus 0.004 0.0077 0.0495
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0359 0.1752
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.0565 0.779
Loa Loa (eye worm) hypothetical protein 0.0036 0.0062 0.0063
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.002 0.0002 0.0002
Echinococcus multilocularis GPCR, family 2 0.0084 0.0249 0.0249
Echinococcus granulosus segment polarity protein dishevelled 0.002 0.0002 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0043 0.0043
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0043 0.0171
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0002 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0109 0.1934
Echinococcus granulosus thioredoxin glutathione reductase 0.004 0.0079 0.0314
Plasmodium falciparum glutathione reductase 0.004 0.0077 0.1367
Schistosoma mansoni survival motor neuron protein 0.0051 0.0119 0.0473
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0108 0.0341 0.1351
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0897 0.4381
Plasmodium vivax pyruvate kinase 2, putative 0.0033 0.0053 0.0935
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0166 0.0565 0.779
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0897 0.4381
Entamoeba histolytica hypothetical protein 0.0108 0.0341 0.6031
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0101 0.0313 0.5536
Onchocerca volvulus 0.009 0.0272 0.1783
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0002
Brugia malayi steroid hormone receptor 0.0031 0.0043 0.0043
Leishmania major hypothetical protein, conserved 0.0208 0.0725 1
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0043 0.0272
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0073 0.0207 0.3656
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0079 0.0228 0.0903
Loa Loa (eye worm) glutaminase 2 0.055 0.2047 0.2057
Loa Loa (eye worm) ShTK domain-containing protein 0.009 0.0272 0.0273
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0159 0.2195
Plasmodium falciparum sphingomyelin synthase 2, putative 0.0136 0.0447 0.7914
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0002 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0597 0.2914
Mycobacterium ulcerans hypothetical protein 0.0024 0.0016 0.0079
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0043
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0043 0.0171
Onchocerca volvulus 0.0078 0.0225 0.1475
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0062 0.1104
Schistosoma mansoni alpha-glucosidase 0.0284 0.1021 0.4046
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0109 0.1934
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0043 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0043 0.0043
Brugia malayi Phosphoglycerate kinase 0.0061 0.0159 0.016
Trichomonas vaginalis pyruvate kinase, putative 0.0065 0.0175 0.0856
Onchocerca volvulus 0.009 0.0272 0.1783
Brugia malayi Pyruvate kinase, muscle isozyme 0.0065 0.0175 0.0176
Loa Loa (eye worm) pyruvate kinase 0.0065 0.0175 0.0176
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0072 0.0203 0.3599
Echinococcus multilocularis sodium:glucose cotransporter 2 0.004 0.0077 0.0077
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0045 0.0045
Plasmodium falciparum pyruvate kinase 0.0065 0.0175 0.31
Entamoeba histolytica hypothetical protein 0.0108 0.0341 0.6031
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0045 0.0177
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0109 0.1934
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0002
Onchocerca volvulus 0.0191 0.0661 0.4358
Echinococcus multilocularis Niemann Pick C1 protein 0.0104 0.0323 0.0323
Onchocerca volvulus 0.0031 0.0045 0.0282
Entamoeba histolytica hypothetical protein 0.0108 0.0341 0.6031
Brugia malayi GH02984p 0.036 0.1312 0.1318
Echinococcus granulosus Niemann Pick C1 protein 0.0104 0.0323 0.1281
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0002
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0043 0.0043
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0166 0.0565 1
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0897 0.4381
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0166 0.0565 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0029 0.0142
Schistosoma mansoni hypothetical protein 0.0084 0.0249 0.0986
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0207 0.2848
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0045 0.0177
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0113 0.0359 0.4945
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.0883 0.0887
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0016 0.0079
Trichomonas vaginalis pyruvate kinase, putative 0.0065 0.0175 0.0856
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0055 0.097
Loa Loa (eye worm) hypothetical protein 0.0136 0.0447 0.0449
Schistosoma mansoni dep domain containing protein 0.002 0.0002 0.0008
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0016 0.0079
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0043 0.0043
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0109 0.011
Brugia malayi Pyruvate kinase, M2 isozyme 0.0065 0.0175 0.0176
Schistosoma mansoni tyrosinase precursor 0.009 0.0272 0.1077
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0897 0.4381
Loa Loa (eye worm) hypothetical protein 0.009 0.0272 0.0273
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0101 0.0313 0.4465
Echinococcus granulosus sodium:glucose cotransporter 2 0.004 0.0077 0.0305
Onchocerca volvulus 0.0051 0.0119 0.0776
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.0565 0.224
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0159 0.2195
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0279 0.1107
Schistosoma mansoni microtubule-associated protein tau 0.0674 0.2523 1
Mycobacterium tuberculosis Probable reductase 0.0091 0.0274 0.4845
Onchocerca volvulus Pyruvate kinase homolog 0.0065 0.0175 0.1145
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0279 0.1107
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0091 0.0274 0.4845
Echinococcus multilocularis pyruvate kinase 0.0033 0.0053 0.0053
Trichomonas vaginalis sucrase-isomaltase, putative 0.0073 0.0207 0.1009
Loa Loa (eye worm) hypothetical protein 0.0065 0.0175 0.0176
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0029 0.0142
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0043 0.0171
Brugia malayi Sodium:solute symporter family protein 0.004 0.0077 0.0077
Brugia malayi ecdysteroid receptor 0.0031 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0043 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0359 0.1752
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0091 0.0274 0.4845
Toxoplasma gondii hypothetical protein 0.002 0.0002 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0562 0.2746
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0043 0.0043
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0043 0.0171
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0108 0.0341 0.0341
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.004 0.0077 0.1361
Trypanosoma brucei pyruvate kinase 1 0.0065 0.0175 0.2415
Entamoeba histolytica pyruvate kinase, putative 0.0045 0.0099 0.1754
Schistosoma mansoni pyruvate kinase 0.0033 0.0053 0.0209
Schistosoma mansoni glutaminase 0.055 0.2047 0.8115
Mycobacterium ulcerans phosphoglycerate kinase 0.0166 0.0565 0.276
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0101 0.0313 0.5536
Schistosoma mansoni hypothetical protein 0.0043 0.0089 0.0353
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0207 0.1009
Toxoplasma gondii hypothetical protein 0.0136 0.0447 0.7914
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0043 0.0043
Echinococcus multilocularis expressed conserved protein 0.0097 0.0299 0.0299
Onchocerca volvulus 0.009 0.0272 0.1783
Trypanosoma brucei phosphoglycerate kinase 0.0166 0.0565 0.779
Onchocerca volvulus 0.0048 0.0109 0.0709
Echinococcus granulosus microtubule associated protein 2 0.0674 0.2523 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0084 0.0249 0.0986
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0897 0.4381
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0072 0.0203 0.2803
Onchocerca volvulus 0.009 0.0272 0.1783
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0159 0.2195
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0136 0.0447 0.2184
Loa Loa (eye worm) hypothetical protein 0.0044 0.0095 0.0096
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0016 0.0222
Echinococcus granulosus Pleckstrin G protein interacting region 0.002 0.0002 0.0008
Toxoplasma gondii thioredoxin reductase 0.004 0.0077 0.1367
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.009 0.0272 0.0273
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0043
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0279 0.1107
Echinococcus multilocularis neutral alpha glucosidase AB 0.0073 0.0207 0.0207
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0043 0.0043
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0084 0.0249 0.025
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.004 0.0077 0.0077
Plasmodium falciparum phosphoglycerate kinase 0.0166 0.0565 1
Chlamydia trachomatis pyruvate kinase 0.0065 0.0175 0.2244
Echinococcus multilocularis pyruvate kinase 0.0033 0.0053 0.0053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0043 0.0043
Onchocerca volvulus 0.0031 0.0043 0.0272
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0043 0.0171
Loa Loa (eye worm) hypothetical protein 0.0036 0.0062 0.0063
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0079 0.0228 0.3139
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0043 0.0043
Mycobacterium tuberculosis Probable oxidoreductase 0.0101 0.0313 0.5536
Schistosoma mansoni phosphoglycerate kinase 0.0166 0.0565 0.224
Loa Loa (eye worm) pyruvate kinase-PB 0.0045 0.0099 0.01
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0079 0.0228 0.0229
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0043 0.0171
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0219 0.0767 0.0771
Plasmodium vivax SET domain protein, putative 0.0031 0.0045 0.0792
Echinococcus granulosus sodium:glucose cotransporter 0.004 0.0077 0.0305
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0139 0.0679
Loa Loa (eye worm) hypothetical protein 0.0036 0.0062 0.0063
Brugia malayi nuclear hormone receptor 0.0031 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0036 0.0062 0.0063
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0002 0.0002
Mycobacterium ulcerans glutaminase 0.055 0.2047 1
Plasmodium vivax glutathione reductase, putative 0.004 0.0077 0.1367
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0043 0.0043
Schistosoma mansoni pyruvate kinase 0.0065 0.0175 0.0694
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0136 0.0447 0.0449
Mycobacterium ulcerans aldehyde dehydrogenase 0.0072 0.0203 0.0993
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0043 0.0171
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0597 0.2914
Trypanosoma brucei trypanothione reductase 0.004 0.0077 0.1065
Mycobacterium tuberculosis Probable dehydrogenase 0.0091 0.0274 0.4845
Leishmania major glycosyl hydrolase-like protein 0.0027 0.0029 0.0402
Plasmodium vivax sphingomyelin synthase 1, putative 0.0136 0.0447 0.7914
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0266 0.095 0.0955
Trypanosoma brucei hypothetical protein, conserved 0.0208 0.0725 1
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0043 0.0171
Schistosoma mansoni high-affinity choline transporter 0.036 0.1312 0.5199
Echinococcus multilocularis microtubule associated protein 2 0.0674 0.2523 0.2523
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0055 0.097
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0079 0.0228 0.403
Trypanosoma cruzi polo-like protein kinase, putative 0.0113 0.0359 0.4945
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.009 0.0272 0.0273
Brugia malayi latrophilin 2 splice variant baaae 0.0182 0.0626 0.0629
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0079 0.0228 0.3139
Echinococcus multilocularis thioredoxin glutathione reductase 0.004 0.0079 0.0079
Echinococcus granulosus lysosomal alpha glucosidase 0.033 0.1198 0.4749
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0109 0.0534
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0062 0.1104
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.033 0.1198 0.1204
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0095 0.0465
Leishmania major pyruvate kinase 0.0065 0.0175 0.2415
Trypanosoma brucei glucosidase, putative 0.0073 0.0207 0.2848
Entamoeba histolytica hypothetical protein 0.0136 0.0447 0.7914
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0043 0.0171
Schistosoma mansoni regulator of G protein signaling 0.002 0.0002 0.0008
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.0136 0.0447 0.0449
Echinococcus multilocularis survival motor neuron protein 1 0.0249 0.0883 0.0883
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0159 0.2195
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0084 0.0249 0.0986
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0562 0.2746
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0043 0.0272
Mycobacterium ulcerans aldehyde dehydrogenase 0.0072 0.0203 0.0993
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0045 0.0177
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0562 0.2746
Brugia malayi Pre-SET motif family protein 0.0219 0.0767 0.0771
Brugia malayi hypothetical protein 0.002 0.0002 0.0002
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0091 0.0274 0.4845
Trichomonas vaginalis hypothetical protein 0.0136 0.0447 0.2184
Echinococcus multilocularis phosphoglycerate kinase 1 0.0166 0.0565 0.0565
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0562 0.2746
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0045 0.0177
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0725 1
Loa Loa (eye worm) pyruvate kinase 0.0065 0.0175 0.0176
Loa Loa (eye worm) hypothetical protein 0.0048 0.0109 0.011
Loa Loa (eye worm) hypothetical protein 0.0136 0.0447 0.0449
Leishmania major pyruvate kinase 0.0065 0.0175 0.2415
Leishmania major phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0136 0.0447 0.6165
Plasmodium falciparum pyruvate kinase 2 0.0033 0.0053 0.0935
Onchocerca volvulus 0.0249 0.0883 0.5829
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0084 0.0249 0.0986
Plasmodium vivax sphingomyelin synthase 2, putative 0.0136 0.0447 0.7914
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0043 0.0043
Onchocerca volvulus Pyruvate kinase homolog 0.0065 0.0175 0.1145
Echinococcus granulosus solute carrier family 5 0.004 0.0077 0.0305
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0166 0.0565 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0072 0.0203 0.0993
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0095 0.0377
Loa Loa (eye worm) hypothetical protein 0.0136 0.0447 0.0449
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0043 0.0043
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0055 0.097
Brugia malayi serine/threonine-protein kinase plk-2 0.0113 0.0359 0.036
Loa Loa (eye worm) glutaminase 0.055 0.2047 0.2057
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0166 0.0565 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0072 0.0203 0.0203
Echinococcus granulosus segment polarity protein dishevelled 0.002 0.0002 0.0008
Entamoeba histolytica hypothetical membrane-spanning protein 0.0136 0.0447 0.7914
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0029 0.0516
Trichomonas vaginalis glutaminase, putative 0.055 0.2047 1
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0359 0.1422
Schistosoma mansoni hypothetical protein 0.0051 0.0119 0.0473
Brugia malayi Glycosyl hydrolases family 31 protein 0.0073 0.0207 0.0208
Brugia malayi DIX domain containing protein 0.002 0.0002 0.0002
Mycobacterium tuberculosis Conserved protein 0.0024 0.0016 0.0285
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0045 0.0177
Loa Loa (eye worm) hypothetical protein 0.0031 0.0043 0.0043
Trypanosoma brucei phosphoglycerate kinase 0.0061 0.0159 0.2195
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0109 0.011
Entamoeba histolytica hypothetical protein 0.0136 0.0447 0.7914
Entamoeba histolytica serine/threonine protein kinase, putative 0.0113 0.0359 0.6347
Schistosoma mansoni hypothetical protein 0.0043 0.0089 0.0353
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0079 0.0228 0.0229

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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