Detailed information for compound 1269771

Basic information

Technical information
  • TDR Targets ID: 1269771
  • Name: (2Z)-2-[[1-(4-methylphenyl)sulfonylindol-3-yl ]methylidene]-1-azabicyclo[2.2.2]octan-3-ol
  • MW: 408.513 | Formula: C23H24N2O3S
  • H donors: 1 H acceptors: 3 LogP: 3.82 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)S(=O)(=O)n1cc(c2c1cccc2)/C=C/1\N2CCC(C1O)CC2
  • InChi: 1S/C23H24N2O3S/c1-16-6-8-19(9-7-16)29(27,28)25-15-18(20-4-2-3-5-21(20)25)14-22-23(26)17-10-12-24(22)13-11-17/h2-9,14-15,17,23,26H,10-13H2,1H3/b22-14-
  • InChiKey: SNSJLAVNBDPZGG-HMAPJEAMSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (2Z)-2-[[1-(4-methylphenyl)sulfonylindol-3-yl]methylene]quinuclidin-3-ol
  • (2Z)-2-[[1-(4-methylphenyl)sulfonyl-3-indolyl]methylene]-3-quinuclidinol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.009 0.1107 0.4547
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0478 0.3278
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0108 0.0083
Echinococcus multilocularis ankyrin repeat protein 0.0162 0.2136 0.2149
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0252 0.0259
Brugia malayi glutathione reductase 0.0179 0.2382 0.2695
Plasmodium falciparum thioredoxin reductase 0.0179 0.2382 1
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0252 0.0259
Echinococcus granulosus survival motor neuron protein 1 0.024 0.3257 0.3292
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0177 0.0177
Giardia lamblia Transglutaminase/protease, putative 0.0369 0.5094 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0259
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0051 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0344 0.0344
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0393 0.261
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.1138 0.4679
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0215 0.0215
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0154 0.074
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0093 0.021
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0062 0.0711 0.2851
Chlamydia trachomatis pyruvate kinase 0.0032 0.0288 0.3511
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0148 0.0691
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0016 0.006 0.0034
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0046 0.0476 0.0514
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0062 0.0711 0.0697
Loa Loa (eye worm) hypothetical protein 0.0032 0.0288 0.03
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0093 0.021
Schistosoma mansoni disulfide oxidoreductase 0.0016 0.006 0.0034
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0016 0.006 0.0034
Brugia malayi phosphofructokinase 0.0106 0.1336 0.1498
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0103 0.0078
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0093 0.021
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0103 0.0078
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0233 0.0233
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0044 0.0044
Brugia malayi glutamate synthase 0.0016 0.006 0.0038
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0062 0.0711 0.1293
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0177 0.0177
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0154 0.0151
Trichomonas vaginalis peptide N-glycanase, putative 0.0369 0.5094 0.5094
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0288 0.1046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0478 0.0478
Schistosoma mansoni sulfide quinone reductase 0.0016 0.006 0.0034
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0016 0.006 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0178 0.0178
Trypanosoma brucei pyruvate kinase 1 0.0032 0.0288 0.1175
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0093 0.0068
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0259
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0288 0.03
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.015 0.1381
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0478 0.1858
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0252 0.023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0103 0.0088
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0226 0.0775
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0744 0.0731
Leishmania major hypothetical protein, conserved 0.0025 0.0175 0.0561
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0154 0.0187
Leishmania major trypanothione reductase 0.0179 0.2382 1
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0252 0.0227
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.1873 0.1881
Mycobacterium leprae Conserved hypothetical protein 0.0369 0.5094 0.8057
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0478 0.1975
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0444 0.0444
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0706 0.1284
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0252 0.0259
Brugia malayi hypothetical protein 0.0019 0.0103 0.0088
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0062 0.0711 0.2853
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0344 0.0344
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0016 0.006 0.0069
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0252 0.0259
Echinococcus multilocularis chromobox protein 1 0.0071 0.0838 0.0827
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1138 0.1138
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.1336 0.5526
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0093 0.0351
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.1336 0.1498
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0175 0.0561
Echinococcus granulosus microtubule associated protein 2 0.0701 0.9842 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.1932 0.1942
Echinococcus granulosus geminin 0.0165 0.218 0.2194
Schistosoma mansoni importin beta-1 0.0028 0.0226 0.0203
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0103 0.0078
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0016 0.006 0.0067
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.1138 0.1272
Schistosoma mansoni nuclear hormone receptor 0.003 0.0252 0.023
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.1336 0.1336
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0436 0.0436
Giardia lamblia DINP protein human, muc B family 0.0019 0.0093 0.0066
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0051 0.0028
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0252 0.0259
Schistosoma mansoni coup transcription factor 0.003 0.0252 0.023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0178 0.0178
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0252 0.0259
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0175 0.0559
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0051
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0062 0.0711 0.2956
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0103 0.0088
Loa Loa (eye worm) hypothetical protein 0.009 0.1107 0.1237
Entamoeba histolytica hypothetical protein 0.0019 0.0103 0.0341
Echinococcus granulosus expressed protein 0.038 0.5252 0.5324
Onchocerca volvulus 0.0031 0.027 0.0244
Leishmania major pyruvate kinase 0.0032 0.0288 0.1046
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0233 0.0807
Echinococcus multilocularis 6 phosphofructokinase 0.0106 0.1336 0.1334
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0233 0.0233
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1138 0.1138
Plasmodium falciparum pyruvate kinase 0.0032 0.0288 0.1044
Trichomonas vaginalis glutamate synthase, putative 0.0016 0.006 0.006
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0101 0.1273 0.127
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.015 0.0451
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1138 0.1138
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0838 0.0838
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0233 0.0233
Giardia lamblia Kinase, PLK 0.0092 0.1138 0.2141
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1138 0.1138
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0233 0.0807
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0071 0.0114
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0096 0.0364
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0062 0.0711 0.2851
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0062 0.0711 0.1293
Echinococcus granulosus pyruvate kinase 0.0017 0.0063 0.0037
Schistosoma mansoni sulfide quinone reductase 0.0016 0.006 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0044 0.0044
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0062 0.0711 0.2853
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0233 0.0807
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0706 0.2831
Echinococcus granulosus pyruvate kinase 0.0032 0.0288 0.0267
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0016 0.006 0.0034
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0103 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0044 0.0044
Schistosoma mansoni survival motor neuron protein 0.0049 0.0525 0.0508
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0044 0.002
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.1138 0.8449
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0249 0.0249
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.1138 0.1132
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0233 0.1356
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.1336 0.1336
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0288 0.03
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.098 0.0972
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0093 0.0351
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0016 0.006 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0478 0.0478
Echinococcus granulosus dna polymerase eta 0.0019 0.0093 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0311 0.0311
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0252 0.023
Brugia malayi Pre-SET motif family protein 0.0625 0.8765 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0062 0.0711 0.2956
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0108 0.0093
Mycobacterium tuberculosis Probable dehydrogenase 0.0408 0.5657 0.8961
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0148 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0093 0.0351
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0062 0.0711 0.2853
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0744 0.0731
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0093 0.0351
Mycobacterium tuberculosis Conserved hypothetical protein 0.0369 0.5094 0.8061
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0478 0.046
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0259
Trichomonas vaginalis mercuric reductase, putative 0.0062 0.0711 0.0711
Echinococcus multilocularis geminin 0.0165 0.218 0.2194
Schistosoma mansoni thyroid hormone receptor 0.003 0.0252 0.023
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0478 0.046
Loa Loa (eye worm) RNA binding protein 0.0064 0.0744 0.0821
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.006 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0093 0.0351
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0016 0.006 0.0038
Brugia malayi hypothetical protein 0.0016 0.0051 0.0028
Brugia malayi nuclear receptor NHR-88 0.003 0.0252 0.0259
Trypanosoma cruzi NADH dehydrogenase, putative 0.0016 0.006 0.0069
Mycobacterium tuberculosis Conserved protein 0.0369 0.5094 0.8061
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0478 0.0478
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0226 0.091
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0016 0.006 0.0034
Brugia malayi 6-phosphofructokinase 0.0106 0.1336 0.1498
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0288 0.0288
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0044 0.0018
Schistosoma mansoni hypothetical protein 0.0165 0.218 0.2194
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0113 0.1447 0.1447
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0288 0.0288
Trichomonas vaginalis importin beta-1, putative 0.0023 0.015 0.015
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.006 0.006
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0444 0.1712
Echinococcus granulosus Transglutaminase 0.0369 0.5094 0.5163
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0016 0.006 0.0212
Schistosoma mansoni pyruvate kinase 0.0032 0.0288 0.0267
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0093 0.021
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.015 0.0451
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0252 0.023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0132 0.1708 0.1924
Loa Loa (eye worm) hypothetical protein 0.0019 0.0103 0.0088
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0175 0.0697
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0252 0.023
Brugia malayi TAR-binding protein 0.0064 0.0744 0.0821
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.1138 0.1132
Brugia malayi Heterochromatin protein 1 0.0071 0.0838 0.0928
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.1138 0.4679
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0103 0.0088
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0062 0.0711 0.2851
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0044 0.0002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0408 0.5657 0.8961
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0311 0.0311
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0478 0.046
Mycobacterium ulcerans pyruvate kinase 0.0032 0.0288 0.0454
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0211 0.0211
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0233 0.0807
Echinococcus granulosus tar DNA binding protein 0.0064 0.0744 0.0731
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.1336 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0051 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0393 0.0393
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.4104 0.4666
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.015 0.0178
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0393 0.0661
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0393 0.0393
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0744 0.0821
Loa Loa (eye worm) hypothetical protein 0.0023 0.0154 0.0146
Toxoplasma gondii selenide, water dikinase 0.0016 0.006 0.0067
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0044 0.0146
Echinococcus granulosus dna polymerase kappa 0.0019 0.0093 0.0068
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0175 0.0559
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0016 0.006 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0044 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0062 0.0711 0.2853
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0044 0.0144
Plasmodium vivax pyruvate kinase, putative 0.0032 0.0288 0.1044
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0103 0.0078
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.098 0.0972
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0062 0.0711 0.0783
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0233 0.2658
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0838 0.0838
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0252 0.0259
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0093 0.0078
Brugia malayi nuclear hormone receptor 0.003 0.0252 0.0259
Giardia lamblia Pyruvate kinase 0.0017 0.0063 0.0006
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0016 0.006 0.0212
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0103 0.0078
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0233 0.0344
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0103 0.0103
Echinococcus multilocularis transient receptor potential cation channel 0.0165 0.2183 0.2197
Plasmodium vivax SET domain protein, putative 0.009 0.1107 0.4547
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0108 0.0083
Echinococcus multilocularis snurportin 1 0.0299 0.4104 0.4154
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0103 0.0078
Schistosoma mansoni microtubule-associated protein tau 0.0701 0.9842 1
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0016 0.006 0.0067
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0252 0.0259
Plasmodium falciparum glutathione reductase 0.0179 0.2382 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0046 0.0476 0.0514
Onchocerca volvulus 0.0101 0.1273 0.125
Echinococcus multilocularis microtubule associated protein 2 0.0701 0.9842 1
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0744 0.0821
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0838 0.0928
Mycobacterium leprae conserved hypothetical protein 0.0023 0.015 0.0144
Schistosoma mansoni kinase 0.0047 0.0492 0.0474
Schistosoma mansoni glutamate synthase 0.0016 0.006 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0227 0.0227
Echinococcus granulosus glutamate synthase 0.0016 0.006 0.0034
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0103 0.0078
Schistosoma mansoni hypothetical protein 0.0049 0.0525 0.0508
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0383 0.0383
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0311 0.0311
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0108 0.0093
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0154 0.0472
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0044 0.0018
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0103 0.0088
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0252 0.023
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0233 0.2658
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.1336 0.1336
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0044 0.0018
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.1138 0.1114
Loa Loa (eye worm) 6-phosphofructokinase 0.0106 0.1336 0.1498
Loa Loa (eye worm) phosphofructokinase 0.0106 0.1336 0.1498
Trichomonas vaginalis phosphofructokinase, putative 0.0106 0.1336 0.1336
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0103 0.0078
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0062 0.0711 0.2853
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0062 0.0711 1
Schistosoma mansoni glutamate synthase 0.0016 0.006 0.0034
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0044 0.0018
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0093 0.0066
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0016 0.006 0.0067
Schistosoma mansoni pyruvate kinase 0.0017 0.0063 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0311 0.0311
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0288 0.0263
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0044 0.002
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0106 0.1336 1
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0016 0.006 0.0034
Leishmania major pyruvate kinase 0.0032 0.0288 0.1046
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0475 0.0475
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0478 0.1858
Brugia malayi RNA, U transporter 1 0.008 0.0964 0.1073
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0154 0.0176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0178 0.0178
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0233 0.0233
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.106 0.1053
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0259
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0093 0.0076
Echinococcus multilocularis pyruvate kinase 0.0032 0.0288 0.0267
Schistosoma mansoni hypothetical protein 0.0016 0.006 0.0034
Onchocerca volvulus 0.0081 0.098 0.0957
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.1138 0.1132
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0227 0.0227
Schistosoma mansoni chromobox protein 0.0071 0.0838 0.0827
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.015 0.0451
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0311 0.114
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0093 0.0351
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0345 0.1413
Schistosoma mansoni hypothetical protein 0.0299 0.4104 0.4154
Loa Loa (eye worm) hypothetical protein 0.0023 0.0148 0.0139
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0154 0.0146
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.006 0.006
Trichomonas vaginalis apoptosis inducing factor, putative 0.0016 0.006 0.006
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.1336 1
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0016 0.006 0.0025
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0057 0.0021
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.009 0.1107 0.1101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0311 0.0311
Brugia malayi chromobox protein homolog 3 0.004 0.0393 0.0419
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0044 0.0002
Onchocerca volvulus 0.0016 0.006 0.0034
Brugia malayi Thioredoxin reductase 0.0179 0.2382 0.2695
Echinococcus multilocularis expressed protein 0.038 0.5252 0.5324
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0016 0.006 0.0069
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0062 0.0711 1
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0226 0.0203
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0016 0.006 0.0025
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0103 0.0088
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0062 0.0711 0.1064
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0179 0.2382 0.3731
Brugia malayi Importin beta-1 subunit 0.0028 0.0226 0.0228
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0093 0.0351
Brugia malayi ecdysteroid receptor 0.003 0.0252 0.0259
Loa Loa (eye worm) hypothetical protein 0.0028 0.0226 0.0228
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0093 0.021
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0093 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0093 0.0351
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0103 0.0078
Plasmodium falciparum importin beta, putative 0.0028 0.0226 0.0775
Loa Loa (eye worm) hypothetical protein 0.0245 0.333 0.378
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0103 0.0103
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.1107 0.1101
Trypanosoma brucei pyruvate kinase 1, putative 0.0032 0.0288 0.1175
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0016 0.006 0.0069
Mycobacterium tuberculosis Probable oxidoreductase 0.0453 0.6308 1
Brugia malayi PXA domain containing protein 0.0019 0.0103 0.0088
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0044 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0177 0.0177
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0093 0.0351
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0062 0.0711 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0393 0.0367
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0706 0.1284
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1138 0.1138
Leishmania major DNA polymerase eta, putative 0.0019 0.0093 0.021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0044 0.0018
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0062 0.0711 0.0697
Brugia malayi RNA binding protein 0.0064 0.0744 0.0821
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0062 0.0711 0.2853
Leishmania major DNA polymerase kappa, putative 0.0019 0.0093 0.021
Leishmania major hypothetical protein, conserved 0.0016 0.006 0.0069
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0154 0.0187
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.006 0.0212
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0259
Loa Loa (eye worm) hypothetical protein 0.0016 0.0051 0.0028
Loa Loa (eye worm) hypothetical protein 0.024 0.3257 0.3697
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0093 0.0093
Mycobacterium ulcerans hypothetical protein 0.0369 0.5094 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0436 0.041
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0252 0.0259
Schistosoma mansoni thyroid hormone receptor 0.003 0.0252 0.023
Leishmania major ATP-dependent phosphofructokinase 0.0106 0.1336 0.5526
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0134 0.0523
Brugia malayi hypothetical protein 0.0124 0.1595 0.1795
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0744 0.0821
Plasmodium falciparum ferrodoxin reductase-like protein 0.0016 0.006 0.0067
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0016 0.006 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0344 0.0344
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0108 0.0083
Mycobacterium ulcerans putative transglutaminase-like protein 0.0369 0.5094 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.015 0.0451
Echinococcus granulosus thioredoxin glutathione reductase 0.0179 0.2389 0.2407
Trypanosoma brucei trypanothione reductase 0.0179 0.2382 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0252 0.0259
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0016 0.006 0.0212
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0252 0.023
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0016 0.006 0.0034
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0252 0.023
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0103 0.0088
Mycobacterium ulcerans transglutaminase family protein 0.0369 0.5094 1
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0103 0.0103
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0016 0.006 0.0038
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0016 0.006 0.0034
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0062 0.0711 0.2851
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0154 0.0187
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0106 0.1336 0.2062
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0453 0.6308 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0044 0.0018
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0154 0.0187
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0016 0.006 0.0034
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0103 0.0078
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0103 0.0078
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0044 0.0146
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0252 0.0259
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0093 0.0076
Leishmania major hypothetical protein, conserved 0.0016 0.006 0.0069
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0093 0.021
Leishmania major importin beta-1 subunit, putative 0.0023 0.015 0.0453
Loa Loa (eye worm) hypothetical protein 0.0323 0.4437 0.5048
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0044 0.0018
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0154 0.0151
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.015 0.0168
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0252 0.023
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0154 0.074
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0252 0.023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.006 0.006
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.1336 0.1334
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0408 0.5657 0.8961
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0093 0.0259
Mycobacterium tuberculosis Hypothetical protein 0.0369 0.5094 0.8061
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0103 0.0078
Trichomonas vaginalis glutamate synthase, putative 0.0016 0.006 0.006
Echinococcus granulosus pyruvate kinase 0.0017 0.0063 0.0037
Schistosoma mansoni pyruvate kinase 0.0032 0.0288 0.0267
Echinococcus multilocularis Transglutaminase 0.0369 0.5094 0.5163
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0252 0.023
Echinococcus granulosus chromobox protein 1 0.0071 0.0838 0.0827
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.015 0.0704
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0625 0.8765 1
Schistosoma mansoni glutamate synthase 0.0016 0.006 0.0034
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0103 0.0078
Loa Loa (eye worm) hypothetical protein 0.0031 0.027 0.0279
Loa Loa (eye worm) hypothetical protein 0.0019 0.0093 0.0076
Brugia malayi Pyruvate kinase, M2 isozyme 0.0032 0.0288 0.03
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0071 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0744 0.0731
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0093 0.0068
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0252 0.023
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0233 0.0807
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0016 0.006 0.0067
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0252 0.0259
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0103 0.0078
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0103 0.0078
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0103 0.0078
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0162 0.2136 0.2149
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0051 0.0025
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0057 0.0021
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0175 0.0559
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0154 0.0472
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0453 0.6308 1
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0436 0.0436
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0175 0.0559
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.098 0.1092
Onchocerca volvulus 0.003 0.0252 0.0227
Loa Loa (eye worm) hypothetical protein 0.0019 0.0103 0.0088
Loa Loa (eye worm) hypothetical protein 0.0019 0.0103 0.0088
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0252 0.023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0051 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0044 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0062 0.0711 0.2853
Echinococcus granulosus histone lysine methyltransferase setb 0.009 0.1107 0.1101
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0233 0.0233
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0103 0.0103
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0408 0.5657 0.8961
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.015 0.0178
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0106 0.1336 0.559
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0744 0.0731
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0706 0.2833
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0154 0.0472
Leishmania major hypothetical protein, conserved 0.0016 0.006 0.0069
Plasmodium vivax thioredoxin reductase, putative 0.0179 0.2382 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0252 0.0259
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0051 0.0025
Loa Loa (eye worm) hypothetical protein 0.0081 0.098 0.1092
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0478 0.0517
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0393 0.1491
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0345 0.1288
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0259
Brugia malayi Thioredoxin family protein 0.0369 0.5094 0.5799
Echinococcus multilocularis glutamate synthase 0.0016 0.006 0.0034
Echinococcus granulosus ankyrin repeat protein 0.0162 0.2136 0.2149
Mycobacterium ulcerans hypothetical protein 0.0369 0.5094 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.015 0.0453
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0154 0.0187
Brugia malayi nuclear receptor RXR 0.0016 0.0051 0.0028
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.015 0.0453
Brugia malayi hypothetical protein 0.0016 0.0051 0.0028
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0408 0.5657 0.8958
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0062 0.0711 0.1293
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0016 0.006 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0211 0.0211
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0062 0.0711 0.2853
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0032 0.0288 0.039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0051 0.0028
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.015 0.015
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0103 0.0078
Schistosoma mansoni 6-phosphofructokinase 0.0106 0.1336 0.1334
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0044 0.002
Mycobacterium tuberculosis Probable reductase 0.0408 0.5657 0.8961
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0062 0.0711 0.2853
Loa Loa (eye worm) hypothetical protein 0.0019 0.0103 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0252 0.0259
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0051
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0062 0.0711 0.2851
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0252 0.023
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0103 0.0103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0252 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0252 0.0259
Plasmodium vivax ferrodoxin reductase, putative 0.0016 0.006 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0215 0.0215
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0103 0.0078
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0108 0.0083
Brugia malayi 6-phosphofructokinase 0.0106 0.1336 0.1498
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0288 0.03
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.1138 0.1272
Entamoeba histolytica hypothetical protein 0.0023 0.015 0.0704
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0103 0.0088
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.1138 0.4679
Loa Loa (eye worm) programmed cell death 8 0.0016 0.006 0.0038
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0103 0.0078
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0103 0.0078
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0093 0.0068
Echinococcus multilocularis pyruvate kinase 0.0017 0.0063 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0311 0.0311
Mycobacterium tuberculosis Conserved hypothetical protein 0.0369 0.5094 0.8061
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0016 0.006 0.0212
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0706 0.0692
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0063 0.0079
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0252 0.023
Echinococcus granulosus pyruvate kinase 0.0017 0.0063 0.0037
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0103 0.0078
Schistosoma mansoni hypothetical protein 0.0165 0.218 0.2194
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0311 0.4273 0.4859
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0016 0.006 0.006
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.1932 0.2181
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0453 0.6308 1
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0103 0.0103
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0016 0.006 0.0034
Brugia malayi isocitrate dehydrogenase 0.0015 0.0044 0.002
Plasmodium vivax glutathione reductase, putative 0.0179 0.2382 1
Trypanosoma cruzi trypanothione reductase, putative 0.0179 0.2382 1
Trichomonas vaginalis glutathione reductase, putative 0.0062 0.0711 0.0711
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0252 0.0259
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0478 0.3278
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0154 0.0176
Loa Loa (eye worm) hypothetical protein 0.0023 0.0154 0.0146
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0252 0.023
Echinococcus multilocularis pyruvate kinase 0.0017 0.0063 0.0037
Onchocerca volvulus 0.0023 0.0154 0.0128
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0706 0.1284
Mycobacterium leprae Probable pyruvate kinase PykA 0.0032 0.0288 0.0366
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0016 0.006 0.0067
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0016 0.006 0.0038
Echinococcus granulosus 6 phosphofructokinase 0.0106 0.1336 0.1334
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0016 0.006 0.006
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0478 0.1858
Trypanosoma brucei NADH dehydrogenase 0.0016 0.006 0.0212
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0252 0.023
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0478 0.1858
Entamoeba histolytica hypothetical protein 0.0023 0.015 0.0704
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0252 0.023
Brugia malayi hypothetical protein 0.024 0.3257 0.3697
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0706 0.1056
Echinococcus multilocularis pyruvate kinase 0.0032 0.0288 0.0267
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0233 0.0807
Echinococcus multilocularis chromobox protein 1 0.0071 0.0838 0.0827
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0252 0.0259
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0103 0.0078
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0093 0.0093
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0475 0.0475
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0093 0.0351
Trichomonas vaginalis set domain proteins, putative 0.0712 1 1
Mycobacterium ulcerans hypothetical protein 0.0023 0.0154 0.0187
Echinococcus granulosus importin subunit beta 1 0.0028 0.0226 0.0203
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0344 0.0344
Toxoplasma gondii NADPH-glutathione reductase 0.0062 0.0711 0.2851
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.015 0.015
Echinococcus multilocularis pyruvate kinase 0.0026 0.0191 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0344 0.0344
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0103 0.0078
Brugia malayi hypothetical protein 0.0016 0.0051 0.0028
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0093 0.0068
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.015 0.059
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0226 0.091
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0252 0.023
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0288 0.1046
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.1107 0.1101
Trypanosoma brucei unspecified product 0.0019 0.0093 0.0351
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0051
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0016 0.006 0.0025
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0103 0.0078
Loa Loa (eye worm) hypothetical protein 0.0016 0.0051 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1138 0.1138
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0093 0.0351
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0311 0.0311
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0093 0.0351
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0063 0.0079
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0063 0.0079
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0016 0.006 0.0069
Onchocerca volvulus 0.0049 0.0525 0.05
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0093 0.0068
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0154 0.074
Brugia malayi Pyruvate kinase, muscle isozyme 0.0032 0.0288 0.03
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0444 0.1712
Trypanosoma cruzi NADH dehydrogenase, putative 0.0016 0.006 0.0069
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0108 0.0093
Schistosoma mansoni hypothetical protein 0.0369 0.5094 0.5163
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0044 0.0018
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0108 0.0083
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0252 0.023
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0016 0.006 0.0067
Plasmodium falciparum thioredoxin reductase 0.0062 0.0711 0.2851
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0062 0.0711 0.2956
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0154 0.0187
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0154 0.0146
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0016 0.006 0.0067
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0016 0.006 0.0034
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0252 0.0259
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.015 0.1381
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0288 0.0263
Entamoeba histolytica hypothetical protein 0.0019 0.0103 0.0341
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0044 0.002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0062 0.0711 0.2853
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0744 0.0731
Giardia lamblia Pyruvate kinase 0.0032 0.0288 0.0454
Entamoeba histolytica phosphofructokinase, putative 0.0106 0.1336 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0154 0.0146
Plasmodium falciparum glutathione reductase 0.0062 0.0711 0.2851
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0016 0.006 0.0025
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0016 0.006 0.0069
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0525 0.057
Treponema pallidum NADH oxidase 0.0062 0.0711 0.5102
Onchocerca volvulus 0.0369 0.5094 0.5081
Brugia malayi hypothetical protein 0.0025 0.0175 0.017
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0044 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0252 0.0259
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0252 0.023
Loa Loa (eye worm) hypothetical protein 0.004 0.0393 0.0419
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0154 0.0187
Echinococcus multilocularis dna polymerase eta 0.0019 0.0093 0.0068
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0071 0.0114
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0252 0.023
Echinococcus granulosus transient receptor potential cation channel 0.0165 0.2183 0.2197
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0154 0.0146
Plasmodium vivax importin-beta 2, putative 0.0028 0.0226 0.0775
Schistosoma mansoni DNA polymerase eta 0.0019 0.0093 0.0068
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0103 0.0078
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0071 0.017
Echinococcus granulosus snurportin 1 0.0299 0.4104 0.4154
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.1932 0.1942
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0478 0.1975
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0252 0.023
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0408 0.5657 0.8961
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0252 0.0227
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0016 0.006 0.0067
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0444 0.0426
Mycobacterium tuberculosis Long conserved protein 0.0369 0.5094 0.8061
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0345 0.1288
Loa Loa (eye worm) hypothetical protein 0.0019 0.0103 0.0088
Brugia malayi SET domain containing protein 0.0015 0.0038 0.0013
Loa Loa (eye worm) hypothetical protein 0.0016 0.0051 0.0028
Brugia malayi Pre-SET motif family protein 0.009 0.1107 0.1237
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0093 0.0351
Echinococcus multilocularis thioredoxin glutathione reductase 0.0179 0.2389 0.2407
Toxoplasma gondii pyruvate kinase PyK1 0.0032 0.0288 0.1044
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0233 0.0233
Echinococcus multilocularis survival motor neuron protein 1 0.024 0.3257 0.3292
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0252 0.023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0057 0.0021
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.098 0.0972
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.006 0.0069
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0175 0.0561
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0252 0.0227
Echinococcus granulosus pyruvate kinase 0.0032 0.0288 0.0267
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0051
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0016 0.006 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0178 0.0178
Entamoeba histolytica hypothetical protein 0.0019 0.0103 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0215 0.0215
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0444 0.1712
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0071 0.0022
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0093 0.0076
Mycobacterium ulcerans 6-phosphofructokinase 0.0106 0.1336 0.2534
Loa Loa (eye worm) hypothetical protein 0.0066 0.0765 0.0845
Mycobacterium leprae Conserved hypothetical protein 0.0369 0.5094 0.8057
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0478 0.0517
Loa Loa (eye worm) glutathione reductase 0.0179 0.2382 0.2695
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0093 0.0078
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0016 0.006 0.0038
Toxoplasma gondii thioredoxin reductase 0.0179 0.2382 1
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0016 0.006 0.0069
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0044 0.0002
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0706 0.0692
Loa Loa (eye worm) hypothetical protein 0.0025 0.0175 0.017
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0106 0.1336 0.2042
Trypanosoma cruzi trypanothione reductase, putative 0.0062 0.0711 0.2853
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0706 0.0692
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0233 0.0233
Giardia lamblia GTOR 0.0046 0.0478 0.0831
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.006 0.0069
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0103 0.0078
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0062 0.0711 0.2853
Leishmania major NADH dehydrogenase, putative 0.0016 0.006 0.0069
Loa Loa (eye worm) acetyltransferase 0.0147 0.1932 0.2181
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0062 0.0711 0.2956
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0103 0.0088
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0706 0.0692
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0252 0.0259
Giardia lamblia NADH oxidase lateral transfer candidate 0.0062 0.0711 0.1293
Echinococcus multilocularis pyruvate kinase 0.0017 0.0063 0.0037
Brugia malayi PXA domain containing protein 0.0019 0.0103 0.0088
Brugia malayi steroid hormone receptor 0.003 0.0252 0.0259
Echinococcus granulosus FTZ F1 alpha 0.003 0.0252 0.023
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0016 0.006 0.0034
Schistosoma mansoni chromobox protein 0.0071 0.0838 0.0827
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0044 0.0018
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0288 0.0263
Giardia lamblia Hypothetical protein 0.0369 0.5094 1
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0103 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0252 0.0259
Trypanosoma brucei polo-like protein kinase 0.0092 0.1138 0.4756
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.1107 0.1101
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0252 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0103 0.0103
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1138 0.1138
Loa Loa (eye worm) thioredoxin reductase 0.0179 0.2382 0.2695
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0252 0.023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0057 0.0021
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0252 0.0259
Echinococcus granulosus chromobox protein 1 0.0071 0.0838 0.0827
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0444 0.0444
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0233 0.0807
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0062 0.0711 0.2853
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0252 0.023
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0103 0.0078
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0016 0.006 0.006
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0051 0.0025
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0062 0.0711 0.0697
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0051 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0263 0.0263
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.009 0.1107 0.1101
Brugia malayi hypothetical protein 0.0019 0.0103 0.0088
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0744 0.0731
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0093 0.0351
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0233 0.1356
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0252 0.023

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.