Detailed information for compound 133591

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 400.922 | Formula: C21H21ClN2O2S
  • H donors: 1 H acceptors: 2 LogP: 4.32 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc2c(c1)c(O)c(c(=O)n2C)C(=S)N(C(C)(C)C)c1ccccc1
  • InChi: 1S/C21H21ClN2O2S/c1-21(2,3)24(14-8-6-5-7-9-14)20(27)17-18(25)15-12-13(22)10-11-16(15)23(4)19(17)26/h5-12,25H,1-4H3
  • InChiKey: BXGGUIGQPNPIHU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0113 0.0474 0.0734
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0033 0.008 0.0121
Giardia lamblia Lysyl-tRNA synthetase 0.008 0.0309 0.134
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.002 0.0062
Schistosoma mansoni cyclin d 0.0062 0.0223 0.0343
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.0992 0.154
Loa Loa (eye worm) cyclin domain-containing protein 0.0062 0.0223 0.0661
Brugia malayi ecdysteroid receptor 0.0033 0.008 0.0325
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0058 0.0171
Entamoeba histolytica hypothetical protein 0.0026 0.0046 0.019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0159 0.0701 0.2078
Trichomonas vaginalis cyclins, putative 0.0481 0.2286 0.7071
Onchocerca volvulus Putative transporter 0.005 0.0164 0.0462
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.002 0.0015 0.0055
Echinococcus granulosus cyclin 0.012 0.051 0.079
Brugia malayi cyclin fold protein 1 variant b 0.0062 0.0223 0.0924
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Leishmania major phosphatidylinositol 3-kinase, putative 0.0027 0.0049 0.0144
Giardia lamblia Kinase, CMGC CDK 0.0218 0.0992 0.4332
Loa Loa (eye worm) hypothetical protein 0.0121 0.0515 0.1527
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0357 0.1675 0.2603
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0046
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Plasmodium falciparum calcium-dependent protein kinase 2 0.0113 0.0474 0.0638
Plasmodium vivax ataxin-2 like protein, putative 0.0057 0.0195 0.026
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0024 0.0037 0.0149
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0003 0.0009
Schistosoma mansoni transient receptor potential channel 0.0146 0.0638 0.0988
Schistosoma mansoni ran 0.0048 0.0155 0.0237
Echinococcus multilocularis geminin 0.0262 0.1207 0.1875
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Schistosoma mansoni lamin 0.003 0.0064 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Loa Loa (eye worm) hypothetical protein 0.0139 0.0601 0.1782
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0083 0.0325 0.0998
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0033 0.008 0.0238
Echinococcus granulosus cyclins 0.0246 0.113 0.1755
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0065 0.0201
Schistosoma mansoni protein kinase 0.0113 0.0474 0.0734
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0018 0.0004 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0033 0.008 0.0325
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0048 0.0155 0.0637
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.008 0.0121
Loa Loa (eye worm) hypothetical protein 0.0062 0.0223 0.0661
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0061 0.0254
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Mycobacterium tuberculosis Probable esterase LipL 0.0029 0.0061 0.0057
Giardia lamblia Hypothetical protein 0.0062 0.0223 0.0965
Trichomonas vaginalis cyclins, putative 0.0062 0.0223 0.069
Onchocerca volvulus 0.005 0.0164 0.0462
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0107 0.0444 0.1373
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0012
Echinococcus multilocularis solute carrier family 22 0.005 0.0164 0.0251
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0125 0.0531 0.1084
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0159 0.0701 0.2927
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0062 0.0223 0.0298
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0036 0.0092 0.0277
Schistosoma mansoni protein kinase 0.0113 0.0474 0.0734
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0048 0.0155 0.0666
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Leishmania major hypothetical protein, conserved 0.0029 0.0061 0.018
Schistosoma mansoni RAR-like nuclear receptor 0.0033 0.008 0.0121
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.002 0.0015 0.0055
Trypanosoma cruzi target of rapamycin kinase 3 0.0044 0.0132 0.0401
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0218 0.0992 0.154
Echinococcus multilocularis cyclin G2 0.0062 0.0223 0.0343
Plasmodium falciparum ataxin-2 like protein, putative 0.0057 0.0195 0.026
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0113 0.0474 0.0734
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0237 0.0234
Brugia malayi hypothetical protein 0.0026 0.0046 0.0182
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0113 0.0474 0.0734
Loa Loa (eye worm) hypothetical protein 0.0062 0.0223 0.0661
Mycobacterium tuberculosis Conserved protein 0.0029 0.0061 0.0057
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.008 0.0309 0.0305
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0207 0.0939 0.2783
Loa Loa (eye worm) sugar transporter 0.005 0.0164 0.0485
Trypanosoma cruzi O-6 methyl-guanine alkyl transferase, putative 0.0673 0.3234 1
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Plasmodium vivax lysine--tRNA ligase, putative 0.008 0.0309 0.0414
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0125 0.0531 0.2314
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.008 0.0121
Schistosoma mansoni hypothetical protein 0.005 0.0165 0.0252
Trypanosoma cruzi glucose transporter, putative 0.005 0.0164 0.0498
Leishmania major glucose transporter/membrane transporter D2, putative 0.0111 0.0462 0.142
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0033 0.008 0.0121
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0337 0.1576 0.245
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0018 0.0003 0.0009
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.002 0.0015 0.0055
Loa Loa (eye worm) hypothetical protein 0.0033 0.008 0.0238
Brugia malayi nuclear receptor NHR-88 0.0033 0.008 0.0325
Echinococcus granulosus GTP binding nuclear protein Ran 0.0048 0.0155 0.0237
Echinococcus granulosus calcium dependent protein kinase 0.0102 0.0422 0.0652
Trypanosoma brucei importin beta-1 subunit, putative 0.0066 0.024 0.104
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0113 0.0474 0.2064
Echinococcus granulosus survival motor neuron protein 1 0.0501 0.2388 0.3714
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Trypanosoma brucei THT1 - hexose transporter, putative 0.0111 0.0462 0.2009
Entamoeba histolytica cyclin, domain containing protein 0.0062 0.0223 0.0965
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0701 0.3374 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0093 0.0373 0.1107
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Echinococcus granulosus short transient receptor potential channel 6 0.0146 0.0638 0.0988
Onchocerca volvulus 0.0033 0.008 0.0088
Mycobacterium tuberculosis Methylated-DNA--protein-cysteine methyltransferase Ogt (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltra 0.2045 1 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0051 0.0169 0.0515
Schistosoma mansoni Cyclin fold protein 0.0062 0.0223 0.0343
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0029 0.0061 0.018
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.002 0.0062
Onchocerca volvulus 0.0062 0.0223 0.0729
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0065 0.0201
Trypanosoma brucei cdc2-related kinase 1 0.0218 0.0992 0.4332
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0024 0.0037 0.0053
Plasmodium falciparum threonine--tRNA ligase 0.002 0.0015 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Brugia malayi beta-lactamase family protein 0.0029 0.0061 0.0243
Plasmodium vivax importin-beta 2, putative 0.0066 0.024 0.0321
Trypanosoma brucei THT1 - hexose transporter, putative 0.0111 0.0462 0.2009
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0237 0.0365
Onchocerca volvulus 0.005 0.0164 0.0462
Trypanosoma cruzi hexose transporter, putative 0.0111 0.0462 0.142
Schistosoma mansoni hypothetical protein 0.0109 0.0453 0.0701
Echinococcus multilocularis cyclin y 0.0062 0.0223 0.0343
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Brugia malayi nuclear receptor RXR 0.0018 0.0003 0.0001
Trypanosoma cruzi cyclin 6, putative 0.0481 0.2286 0.7068
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Chlamydia trachomatis proline--tRNA ligase 0.0038 0.0103 0.0272
Toxoplasma gondii facilitative glucose transporter GT1 0.0357 0.1675 0.3415
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.005 0.0164 0.0704
Schistosoma mansoni transient receptor potential channel 0.0221 0.1007 0.1563
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0024 0.0037 0.0053
Giardia lamblia Cyclin fold protein 1, putative 0.0062 0.0223 0.0965
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0481 0.2286 0.7068
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0024 0.0037 0.0149
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0107 0.0444 0.044
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Onchocerca volvulus 0.005 0.0164 0.0462
Giardia lamblia Threonyl-tRNA synthetase 0.002 0.0015 0.0055
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0237 0.0365
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0197 0.0886 0.1375
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0061 0.0078
Brugia malayi steroid hormone receptor 0.0033 0.008 0.0325
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.002 0.0062
Loa Loa (eye worm) cyclin domain-containing protein 0.0175 0.0779 0.2308
Trypanosoma cruzi cyclin 9, putative 0.0062 0.0223 0.0682
Trichomonas vaginalis cyclin B3, putative 0.0062 0.0223 0.069
Trichomonas vaginalis cyclin B, putative 0.0481 0.2286 0.7071
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0113 0.0474 0.0638
Echinococcus granulosus solute carrier family 22 0.005 0.0164 0.0251
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0024 0.0037 0.0105
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.018
Plasmodium vivax CDK-related protein kinase 6, putative 0.1517 0.7397 1
Loa Loa (eye worm) hypothetical protein 0.0159 0.0701 0.2078
Leishmania major myo-inositol/proton symporter (MIT) 0.005 0.0164 0.0498
Loa Loa (eye worm) hypothetical protein 0.0033 0.008 0.0238
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0357 0.1675 0.2603
Brugia malayi Cyclin, N-terminal domain containing protein 0.0062 0.0223 0.0924
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0029 0.0061 0.0057
Trichomonas vaginalis glucose transporter, putative 0.0111 0.0462 0.1428
Giardia lamblia Sugar-proton symporter 0.005 0.0164 0.0704
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0165 0.0488
Plasmodium vivax protein kinase Crk2 0.0218 0.0992 0.1338
Loa Loa (eye worm) hypothetical protein 0.0033 0.008 0.0238
Schistosoma mansoni cyclin B3 0.0337 0.1576 0.245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0123 0.038
Echinococcus multilocularis calcium dependent protein kinase 0.0102 0.0422 0.0652
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0051 0.0169 0.0728
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0107 0.0444 0.0687
Loa Loa (eye worm) CYL-1 protein 0.0062 0.0223 0.0661
Schistosoma mansoni importin beta-1 0.0066 0.024 0.037
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0048 0.0155 0.0237
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Onchocerca volvulus 0.005 0.0164 0.0462
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0237 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0086 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0164 0.0506
Onchocerca volvulus 0.005 0.0164 0.0462
Echinococcus multilocularis calcium activated potassium channel 0.0018 0.0006 0.0005
Echinococcus multilocularis cyclin dependent kinase 9 0.0056 0.0193 0.0296
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0033 0.008 0.0088
Trypanosoma brucei hypothetical protein, conserved 0.0274 0.1266 0.5529
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0096 0.0295
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0068 0.025 0.0246
Toxoplasma gondii HEAT repeat-containing protein 0.0066 0.024 0.049
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Brugia malayi Major Facilitator Superfamily protein 0.005 0.0164 0.0674
Mycobacterium ulcerans threonyl-tRNA synthetase 0.002 0.0015 0.0012
Entamoeba histolytica cell division protein kinase 2, putative 0.0218 0.0992 0.4332
Trichomonas vaginalis CMGC family protein kinase 0.0018 0.0003 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trichomonas vaginalis importin beta-1, putative 0.0053 0.0179 0.0554
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0132 0.0409
Loa Loa (eye worm) cyclin domain-containing protein 0.0062 0.0223 0.0661
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0038 0.0103 0.0099
Trypanosoma cruzi PAB1-binding protein , putative 0.0057 0.0195 0.0596
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0357 0.1675 0.2603
Onchocerca volvulus 0.003 0.0064 0.0014
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0068 0.025 0.0246
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0004 0.0003
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0029 0.0061 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0111 0.0344
Loa Loa (eye worm) major facilitator superfamily transporter 0.005 0.0164 0.0485
Brugia malayi hypothetical protein 0.0062 0.0223 0.0924
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0044 0.0133 0.0394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0086 0.0267
Echinococcus granulosus calcium activated potassium channel 0.0018 0.0006 0.0005
Schistosoma mansoni hypothetical protein 0.005 0.0165 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0164 0.0506
Echinococcus granulosus cyclin k 0.0062 0.0223 0.0343
Entamoeba histolytica protein kinase, putative 0.0083 0.0325 0.1412
Echinococcus granulosus synaptic vesicle 2 protein 0.005 0.0164 0.0251
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Brugia malayi Cam kinase protein 1 0.0113 0.0474 0.1976
Leishmania major cyclin 9, putative 0.0062 0.0223 0.0682
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0062 0.0223 0.0965
Brugia malayi Major Facilitator Superfamily protein 0.005 0.0164 0.0674
Trypanosoma cruzi mitotic cyclin, putative 0.0062 0.0223 0.0682
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0113 0.0474 0.1976
Schistosoma mansoni cyclin G2 0.0062 0.0223 0.0343
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0083 0.0325 0.0964
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.0182
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0218 0.0992 0.3062
Toxoplasma gondii isocitrate dehydrogenase 0.0024 0.0037 0.0075
Schistosoma mansoni hypothetical protein 0.0701 0.3374 0.525
Mycobacterium tuberculosis Probable lipase LipD 0.0029 0.0061 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Schistosoma mansoni thyroid hormone receptor 0.0033 0.008 0.0121
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0187 0.0838 0.0835
Brugia malayi Muscleblind-like protein 0.0121 0.0515 0.2148
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0033 0.008 0.0121
Echinococcus granulosus cyclin B3 1 0.0246 0.113 0.1755
Echinococcus granulosus dual specificity 0.0083 0.0325 0.0502
Schistosoma mansoni hypothetical protein 0.132 0.6424 1
Trichomonas vaginalis D-aminoacylase, putative 0.0029 0.0061 0.0188
Giardia lamblia G2/mitotic-specific cyclin B 0.0481 0.2286 1
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.002 0.0015 0.0012
Echinococcus granulosus beta LACTamase domain containing family member 0.0029 0.0061 0.009
Loa Loa (eye worm) hypothetical protein 0.0075 0.0286 0.0846
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0062 0.0223 0.0343
Schistosoma mansoni sugar transporter 0.005 0.0164 0.0251
Trichomonas vaginalis cyclin B3, putative 0.0062 0.0223 0.069
Brugia malayi hypothetical protein 0.0036 0.0096 0.0393
Brugia malayi hypothetical protein 0.0018 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.018
Entamoeba histolytica cyclin, domain containing protein 0.0062 0.0223 0.0965
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0169 0.0523
Loa Loa (eye worm) major facilitator superfamily transporter 0.005 0.0164 0.0485
Trypanosoma brucei sugar transporter, putative 0.005 0.0164 0.0704
Toxoplasma gondii cyclin 4, putative 0.0062 0.0223 0.0455
Leishmania major hypothetical protein, conserved 0.005 0.0164 0.0498
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0992 0.3068
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0992 0.3068
Loa Loa (eye worm) hypothetical protein 0.0113 0.0474 0.1405
Echinococcus granulosus muscleblind protein 0.0121 0.0515 0.0798
Echinococcus multilocularis cyclin G2 0.0062 0.0223 0.0343
Entamoeba histolytica cyclin C, putative 0.0062 0.0223 0.0965
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.002 0.0062
Loa Loa (eye worm) haspin protein kinase 0.0018 0.0003 0.0008
Schistosoma mansoni thyroid hormone receptor 0.0033 0.008 0.0121
Trichomonas vaginalis cyclin B3, putative 0.0246 0.113 0.3494
Trichomonas vaginalis CMGC family protein kinase 0.0018 0.0003 0.0009
Entamoeba histolytica protein kinase domain containing protein 0.0083 0.0325 0.1412
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0033 0.008 0.0121
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.002 0.0015 0.0039
Echinococcus granulosus GPCR family 2 0.005 0.0165 0.0252
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.008 0.0121
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Schistosoma mansoni steroid hormone receptor ad4bp 0.0033 0.008 0.0121
Schistosoma mansoni hypothetical protein 0.0262 0.1207 0.1875
Trypanosoma brucei glucose transporter, putative 0.0111 0.0462 0.2009
Brugia malayi Sugar transporter family protein 0.005 0.0164 0.0674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0086 0.0266
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.008 0.0325
Trypanosoma cruzi hexose transporter, putative 0.005 0.0164 0.0498
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0029 0.0061 0.009
Echinococcus granulosus cyclin dependent kinase 1 0.0218 0.0992 0.154
Trichomonas vaginalis CMGC family protein kinase 0.0018 0.0003 0.0009
Echinococcus multilocularis cyclins 0.0246 0.113 0.1755
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0062 0.0223 0.0455
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Loa Loa (eye worm) glycyl-tRNA synthetase 0.002 0.0015 0.0046
Echinococcus granulosus G1:S specific cyclin D1 0.0062 0.0223 0.0343
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.002 0.0015 0.002
Echinococcus granulosus cyclins 0.0246 0.113 0.1755
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0024 0.0037 0.0046
Echinococcus granulosus transient receptor potential gamma protein 0.0221 0.1007 0.1563
Trypanosoma cruzi cdc2-related kinase 1 0.0218 0.0992 0.3062
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0223 0.069
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0003 0.0009
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.003 0.0042
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Mycobacterium ulcerans lysyl-tRNA synthetase 0.008 0.0309 0.0305
Trichomonas vaginalis cyclins, putative 0.0062 0.0223 0.069
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Schistosoma mansoni hypothetical protein 0.0062 0.0223 0.0343
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trichomonas vaginalis cyclins, putative 0.0246 0.113 0.3494
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0033 0.008 0.0121
Echinococcus multilocularis musashi 0.003 0.0064 0.0095
Brugia malayi Protein kinase domain containing protein 0.0218 0.0992 0.4147
Plasmodium vivax calcium-dependent protein kinase, putative 0.0113 0.0474 0.0638
Entamoeba histolytica hypothetical protein 0.0083 0.0325 0.1412
Brugia malayi CXXC zinc finger family protein 0.0093 0.0373 0.1554
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.002 0.0062
Brugia malayi hypothetical protein 0.0057 0.0195 0.0807
Echinococcus granulosus Cyclin L1 0.0062 0.0223 0.0343
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0049 0.016 0.0473
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0033 0.008 0.0238
Brugia malayi Sugar transporter family protein 0.005 0.0164 0.0674
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Trichomonas vaginalis glucose transporter, putative 0.0111 0.0462 0.1428
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0051 0.0169 0.0515
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0009
Trypanosoma brucei glucose transporter, putative 0.0111 0.0462 0.2009
Trypanosoma cruzi cdc2-related kinase 1 0.0218 0.0992 0.3062
Brugia malayi cell division control protein 2 homolog 0.0218 0.0992 0.4147
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0218 0.0992 0.294
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0057 0.0195 0.0579
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0033 0.008 0.0121
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0113 0.0474 0.0968
Echinococcus multilocularis cyclin B3 1 0.0246 0.113 0.1755
Echinococcus granulosus TRP transient receptor potential channel 0.0082 0.0322 0.0497
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0033 0.008 0.0121
Loa Loa (eye worm) hypothetical protein 0.0481 0.2286 0.6777
Plasmodium vivax proline--tRNA ligase, putative 0.0125 0.0531 0.0715
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0061 0.018
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0164 0.0506
Entamoeba histolytica cyclin, putative 0.0481 0.2286 1
Loa Loa (eye worm) cyclin domain-containing protein 0.0062 0.0223 0.0661
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0062 0.0223 0.0298
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0051 0.0169 0.0515
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0096 0.0295
Schistosoma mansoni hypothetical protein 0.0102 0.0421 0.0651
Entamoeba histolytica cell division protein kinase 2, putative 0.0225 0.1025 0.4478
Plasmodium falciparum calcium-dependent protein kinase 5 0.0113 0.0474 0.0638
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Echinococcus multilocularis cyclin 0.012 0.051 0.079
Plasmodium vivax hexose transporter 0.0357 0.1675 0.2261
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0024 0.0037 0.0046
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.008 0.0121
Onchocerca volvulus 0.005 0.0164 0.0462
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0083 0.0325 0.0998
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0107 0.0444 0.0687
Leishmania major mitotic cyclin, putative 0.0062 0.0223 0.0682
Echinococcus multilocularis beta LACTamase domain containing family member 0.0029 0.0061 0.009
Entamoeba histolytica protein kinase, putative 0.0113 0.0474 0.2064
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0107 0.0444 0.1849
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.002 0.0015 0.0055
Trichomonas vaginalis glucose transporter, putative 0.005 0.0164 0.0506
Trichomonas vaginalis protein kinase atmrk1, putative 0.0018 0.0003 0.0009
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0051 0.0169 0.0728
Echinococcus multilocularis synaptic vesicle 2 protein 0.005 0.0164 0.0251
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0048 0.0155 0.0471
Schistosoma mansoni hypothetical protein 0.005 0.0165 0.0252
Trichomonas vaginalis cyclin D, putative 0.0246 0.113 0.3494
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0024 0.0037 0.0053
Mycobacterium ulcerans hypothetical protein 0.0029 0.0061 0.0057
Mycobacterium leprae Probable lipase LipE 0.0029 0.0061 0.0057
Plasmodium vivax sugar transporter, putative 0.005 0.0164 0.0218
Entamoeba histolytica cyclin family protein 0.0246 0.113 0.4936
Loa Loa (eye worm) cyclin domain-containing protein 0.0337 0.1576 0.4671
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0125 0.0531 0.1636
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.002 0.0062
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0051 0.0169 0.0697
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0024 0.0037 0.0033
Echinococcus multilocularis cpg binding protein 0.0098 0.0399 0.0618
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0113 0.0474 0.0638
Trypanosoma brucei importin beta-1 subunit, putative 0.0066 0.024 0.104
Echinococcus multilocularis glycyl tRNA synthetase 0.002 0.0015 0.002
Onchocerca volvulus Protein ultraspiracle homolog 0.0033 0.008 0.0088
Echinococcus granulosus cyclin G2 0.0062 0.0223 0.0343
Schistosoma mansoni cyclins 0.0246 0.113 0.1755
Schistosoma mansoni sugar transporter 0.005 0.0164 0.0251
Brugia malayi Cyclin, N-terminal domain containing protein 0.0062 0.0223 0.0924
Schistosoma mansoni cyclin l 0.0062 0.0223 0.0343
Mycobacterium ulcerans sugar transporter 0.005 0.0164 0.016
Trypanosoma brucei cyclin 3 0.0062 0.0223 0.0965
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0003 0.0009
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.058 0.2777 0.5663
Echinococcus granulosus cpg binding protein 0.0098 0.0399 0.0618
Echinococcus granulosus Threonyl tRNA synthetase C 0.002 0.0015 0.002
Toxoplasma gondii target of rapamycin (TOR), putative 0.0042 0.0123 0.0251
Chlamydia trachomatis methylated-DNA protein-cysteine methyltransferase 0.0673 0.3234 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.0062 0.0223 0.0924
Onchocerca volvulus 0.005 0.0164 0.0462
Trypanosoma cruzi mitotic cyclin, putative 0.0062 0.0223 0.0682
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0068 0.0251 0.0386
Schistosoma mansoni transient receptor potential channel 4 0.0221 0.1007 0.1563
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0033 0.008 0.0325
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Echinococcus multilocularis cyclins 0.0246 0.113 0.1755
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0027 0.0049 0.0204
Onchocerca volvulus 0.0102 0.0421 0.1616
Mycobacterium ulcerans integral membrane transport protein 0.005 0.0164 0.016
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0026 0.0046 0.0068
Echinococcus granulosus short transient receptor potential channel 6 0.0146 0.0638 0.0988
Echinococcus granulosus cyclin y 0.0062 0.0223 0.0343
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0018 0.0003 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0029 0.0061 0.0188
Trichomonas vaginalis sugar transporter, putative 0.0111 0.0462 0.1428
Entamoeba histolytica hypothetical protein 0.0026 0.0046 0.019
Echinococcus granulosus solute carrier family 22 0.005 0.0164 0.0251
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.002 0.0062
Giardia lamblia Cyclin A 0.0246 0.113 0.4936
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0003 0.0009
Entamoeba histolytica hypothetical protein 0.0026 0.0046 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0092 0.0286
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.002 0.0015 0.0012
Mycobacterium ulcerans lysyl-tRNA synthetase 0.008 0.0309 0.0305
Giardia lamblia Hexose transporter 0.005 0.0164 0.0704
Leishmania major hypothetical protein, conserved 0.0673 0.3234 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0357 0.1675 0.2603
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0235 0.1073 0.318
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0113 0.0474 0.0734
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0218 0.0992 0.294
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Echinococcus granulosus cyclin y 0.0062 0.0223 0.0343
Onchocerca volvulus 0.0093 0.0373 0.1405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0123 0.038
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.002 0.0015 0.0053
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0223 0.0298
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0026 0.0046 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Echinococcus granulosus cyclin dependent kinase 0.0218 0.0992 0.154
Trypanosoma cruzi O-6 methyl-guanine alkyl transferase, putative 0.0673 0.3234 1
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0062 0.0223 0.0343
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Plasmodium vivax cyclin homologue, putative 0.0062 0.0223 0.0298
Trypanosoma brucei glucose transporter, putative 0.0111 0.0462 0.2009
Entamoeba histolytica cyclin, putative 0.0246 0.113 0.4936
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0018 0.0004 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Schistosoma mansoni glucose transporter 0.005 0.0164 0.0251
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.002 0.0062
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0165 0.0252
Schistosoma mansoni glucose transport protein 0.0357 0.1675 0.2603
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0056 0.0223
Brugia malayi Cyclin, N-terminal domain containing protein 0.0062 0.0223 0.0924
Echinococcus multilocularis snurportin 1 0.0701 0.3374 0.525
Echinococcus multilocularis importin subunit beta 1 0.0066 0.024 0.037
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0033 0.008 0.0238
Leishmania major hypothetical protein, conserved 0.0018 0.0004 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0033 0.008 0.0238
Trypanosoma brucei glucose transporter, putative 0.0111 0.0462 0.2009
Schistosoma mansoni cyclin G 0.0062 0.0223 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0086 0.0267
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0113 0.0474 0.1405
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0421 0.1752
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Trypanosoma brucei PAB1-binding protein , putative 0.0057 0.0195 0.0843
Leishmania major cyclin 0.0481 0.2286 0.7068
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0062 0.0223 0.0298
Onchocerca volvulus 0.005 0.0164 0.0462
Loa Loa (eye worm) hypothetical protein 0.0109 0.0453 0.1342
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Loa Loa (eye worm) cyclin domain-containing protein 0.0062 0.0223 0.0661
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0125 0.0531 0.1636
Giardia lamblia GTOR 0.0051 0.0169 0.0728
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.008 0.0309 0.0947
Toxoplasma gondii LsmAD domain-containing protein 0.0057 0.0195 0.0398
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0082 0.0322 0.0497
Schistosoma mansoni cyclin B 0.0481 0.2286 0.3556
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0357 0.1675 0.2603
Toxoplasma gondii protein kinase, putative 0.1011 0.4903 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0659 0.3167 0.4927
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0068 0.025 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0223 0.069
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.007 0.0261 0.0806
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0024 0.0037 0.0149
Onchocerca volvulus Cyclin L homolog 0.0062 0.0223 0.0729
Brugia malayi beta-lactamase family protein 0.0029 0.0061 0.0243
Mycobacterium tuberculosis Conserved protein 0.0029 0.0061 0.0057
Plasmodium falciparum calcium-dependent protein kinase 3 0.0113 0.0474 0.0638
Schistosoma mansoni hypothetical protein 0.0025 0.0042 0.006
Echinococcus multilocularis cyclins 0.0246 0.113 0.1755
Loa Loa (eye worm) cyclin C 0.012 0.051 0.1511
Brugia malayi Importin beta-1 subunit 0.0066 0.024 0.0996
Schistosoma mansoni ran 0.0048 0.0155 0.0237
Echinococcus multilocularis cyclin y 0.0062 0.0223 0.0343
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0237 0.0234
Trypanosoma brucei cyclin 9 0.0062 0.0223 0.0965
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0003 0.0001
Loa Loa (eye worm) threonyl-tRNA synthetase 0.002 0.0015 0.0046
Onchocerca volvulus 0.005 0.0164 0.0462
Mycobacterium ulcerans beta-lactamase 0.0029 0.0061 0.0057
Trichomonas vaginalis cyclins, putative 0.0481 0.2286 0.7071
Onchocerca volvulus 0.003 0.0064 0.0014
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0064 0.0256
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0083 0.0325 0.0998
Leishmania major GTP-binding protein, putative 0.0048 0.0155 0.0471
Schistosoma mansoni cpg binding protein 0.0093 0.0373 0.0577
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0033 0.008 0.0325
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0165 0.0252
Brugia malayi Sugar transporter family protein 0.0357 0.1675 0.7009
Giardia lamblia Glycyl-tRNA synthetase 0.002 0.0015 0.0055
Toxoplasma gondii sugar transporter ST3 0.005 0.0164 0.0334
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0033 0.008 0.0238
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trichomonas vaginalis cyclin D, putative 0.0062 0.0223 0.069
Plasmodium falciparum protein kinase 5 0.0218 0.0992 0.1338
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0223 0.069
Echinococcus granulosus Sugar transporter ERD6 protein 0.005 0.0164 0.0251
Echinococcus granulosus oligomeric golgi complex subunit 3 0.012 0.051 0.079
Echinococcus granulosus cyclin G2 0.0062 0.0223 0.0343
Brugia malayi Protein kinase domain containing protein 0.0083 0.0325 0.1352
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0009
Plasmodium vivax cyclin 4, putative 0.0062 0.0223 0.0298
Plasmodium falciparum cyclin 0.0246 0.113 0.1524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0132 0.0409
Echinococcus multilocularis cyclin b3 0.0246 0.113 0.1755
Echinococcus granulosus geminin 0.0262 0.1207 0.1875
Echinococcus multilocularis cyclins 0.0246 0.113 0.1755
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0044 0.0132 0.0401
Echinococcus granulosus cyclin t1 0.0062 0.0223 0.0343
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.003 0.0042
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0051 0.0169 0.0259
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0165 0.0252
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0048 0.0155 0.0206
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Loa Loa (eye worm) beta-lactamase 0.0029 0.0061 0.018
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0003 0.0001
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0218 0.0992 0.2023
Echinococcus granulosus ecdysone induced protein 78C 0.0033 0.008 0.0121
Echinococcus granulosus neuropeptide s receptor 0.0496 0.2361 0.3673
Trypanosoma cruzi hexose transporter, putative 0.0111 0.0462 0.142
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0062 0.0223 0.0343
Trichomonas vaginalis cyclins, putative 0.0297 0.138 0.4266
Loa Loa (eye worm) steroid hormone receptor 0.0033 0.008 0.0238
Schistosoma mansoni g1/s-specific cyclin C 0.012 0.051 0.079
Echinococcus granulosus cyclin b3 0.0246 0.113 0.1755
Brugia malayi isocitrate dehydrogenase 0.0024 0.0037 0.0143
Echinococcus multilocularis survival motor neuron protein 1 0.0501 0.2388 0.3714
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Schistosoma mansoni cpg binding protein 0.0098 0.0399 0.0618
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.002 0.0062
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.002 0.0015 0.0053
Toxoplasma gondii sugar transporter ST2 0.005 0.0164 0.0334
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0474 0.1466
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0083 0.0256
Echinococcus granulosus dnaJ subfamily B 0.132 0.6424 1
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Onchocerca volvulus Cyclin L homolog 0.0062 0.0223 0.0729
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0237 0.0234
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0068 0.0251 0.0386
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0237 0.0365
Brugia malayi hypothetical protein 0.0018 0.0003 0.0001
Entamoeba histolytica hypothetical protein 0.0026 0.0046 0.019
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.002 0.0062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0033 0.008 0.0238
Schistosoma mansoni cyclin k 0.0062 0.0223 0.0343
Plasmodium falciparum calcium-dependent protein kinase 1 0.0113 0.0474 0.0638
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.005 0.0164 0.016
Echinococcus granulosus transient receptor potential ion channel A 0.0214 0.097 0.1507
Brugia malayi photoreceptor-specific nuclear receptor 0.0033 0.008 0.0325
Schistosoma mansoni lysyl-tRNA synthetase 0.008 0.0309 0.0477
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.003 0.0042
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.005 0.0164 0.0251
Loa Loa (eye worm) hypothetical protein 0.0082 0.0322 0.0954
Echinococcus multilocularis dual specificity 0.0083 0.0325 0.0502
Schistosoma mansoni hypothetical protein 0.0026 0.0046 0.0068
Toxoplasma gondii histone lysine methyltransferase SET1 0.0176 0.0782 0.1595
Echinococcus granulosus lamin 0.003 0.0064 0.0095
Plasmodium falciparum hexose transporter 0.0357 0.1675 0.2261
Echinococcus granulosus cyclins 0.0062 0.0223 0.0343
Trypanosoma cruzi hexose transporter 0.0111 0.0462 0.142
Brugia malayi Cyclin, N-terminal domain containing protein 0.0062 0.0223 0.0924
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Echinococcus granulosus cyclins 0.0246 0.113 0.1755
Echinococcus granulosus General substrate transporter 0.0306 0.1427 0.2218
Loa Loa (eye worm) hypothetical protein 0.005 0.0165 0.0488
Echinococcus multilocularis lamin dm0 0.003 0.0064 0.0095
Echinococcus granulosus lamin dm0 0.003 0.0064 0.0095
Trichomonas vaginalis cyclin H, putative 0.0054 0.0185 0.0573
Plasmodium vivax glycine--tRNA ligase, putative 0.002 0.0015 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.002 0.0062
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Onchocerca volvulus 0.005 0.0164 0.0462
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0062 0.0223 0.0455
Onchocerca volvulus 0.0481 0.2286 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0036 0.0092 0.0274
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.002 0.0062
Leishmania major glucose transporter, lmgt1 0.0111 0.0462 0.142
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0048 0.0155 0.0459
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0051 0.0169 0.0728
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0113 0.0474 0.0968
Echinococcus granulosus neuropeptide receptor A26 0.0496 0.2361 0.3673
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0113 0.0474 0.0734
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0029 0.0061 0.0243
Toxoplasma gondii hypothetical protein 0.0062 0.0223 0.0455
Echinococcus granulosus cyclin dependent kinase 9 0.0049 0.016 0.0244
Echinococcus granulosus cyclin dependent kinase 9 0.0056 0.0193 0.0296
Trichomonas vaginalis myo-inositol transporter, putative 0.005 0.0164 0.0506
Brugia malayi glycyl-tRNA synthetase 0.002 0.0015 0.0053
Echinococcus multilocularis isocitrate dehydrogenase 0.0024 0.0037 0.0053
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0033 0.008 0.0121
Trichomonas vaginalis cyclin B, putative 0.0246 0.113 0.3494
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0033 0.008 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0004 0.0003
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0053 0.0179 0.0554
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.018
Echinococcus granulosus snurportin 1 0.0701 0.3374 0.525
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0223 0.0682
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0132 0.0409
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0033 0.008 0.0325
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0132 0.0409
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0107 0.0444 0.0687
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0113 0.0474 0.0968
Trypanosoma cruzi cdc2-related kinase 3 0.0218 0.0992 0.3062
Trichomonas vaginalis helicase, putative 0.0021 0.002 0.0062
Schistosoma mansoni retinoic acid receptor RXR 0.0033 0.008 0.0121
Brugia malayi Latrophilin receptor protein 2 0.005 0.0165 0.0679
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0083 0.0325 0.1412
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0051 0.0169 0.0515
Trypanosoma cruzi cyclin, putative 0.0481 0.2286 0.7068
Loa Loa (eye worm) hypothetical protein 0.0072 0.0272 0.0807
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.003 0.0042
Toxoplasma gondii ABC1 family protein 0.0029 0.0061 0.0124
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0218 0.0992 0.3062
Trypanosoma brucei mitotic cyclin 0.0062 0.0223 0.0965
Onchocerca volvulus Bile acid receptor homolog 0.0033 0.008 0.0088
Schistosoma mansoni cpg binding protein 0.0098 0.0399 0.0618
Brugia malayi intermediate filament protein 0.003 0.0064 0.0256
Schistosoma mansoni sugar transporter 0.005 0.0164 0.0251
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Echinococcus granulosus FTZ F1 alpha 0.0033 0.008 0.0121
Toxoplasma gondii cyclin dependent kinase binding protein 0.0062 0.0223 0.0455
Echinococcus granulosus cyclins 0.0246 0.113 0.1755
Echinococcus multilocularis ecdysone induced protein 78C 0.0033 0.008 0.0121
Echinococcus multilocularis lamin 0.003 0.0064 0.0095
Toxoplasma gondii sugar transporter ST1 0.005 0.0164 0.0334
Loa Loa (eye worm) intermediate filament protein 0.003 0.0064 0.019
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0113 0.0474 0.0638
Brugia malayi Cyclin, N-terminal domain containing protein 0.0481 0.2286 0.9575
Mycobacterium ulcerans DNA-methyltransferase (modification methylase) 0.0274 0.1266 0.1262
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0068 0.0251 0.0386
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.002 0.0015 0.0048
Trypanosoma cruzi PAB1-binding protein , putative 0.0057 0.0195 0.0596
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0053 0.0179 0.0554
Onchocerca volvulus 0.005 0.0164 0.0462
Echinococcus multilocularis Sugar transporter ERD6 protein 0.005 0.0164 0.0251
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0113 0.0474 0.0734
Echinococcus multilocularis solute carrier family 22 0.005 0.0164 0.0251
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0068 0.0251 0.1041
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0992 0.3068
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0024 0.0034 0.0139
Schistosoma mansoni survival motor neuron protein 0.0102 0.0421 0.0651
Trichomonas vaginalis methylated-DNA--protein-cysteine methyltransferase, putative 0.0673 0.3234 1
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.002 0.0015 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0123 0.038
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0029 0.0061 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.002 0.0062
Plasmodium falciparum protein kinase 6 0.1517 0.7397 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.002 0.0062
Echinococcus multilocularis muscleblind protein 0.0121 0.0515 0.0798
Trypanosoma brucei glucose transporter, putative 0.0111 0.0462 0.2009
Trichomonas vaginalis cyclin A, putative 0.0062 0.0223 0.069
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0036 0.0092 0.0392
Echinococcus multilocularis cyclin k 0.0062 0.0223 0.0343
Toxoplasma gondii transporter, major facilitator family protein 0.005 0.0164 0.0334
Brugia malayi Cyclin, N-terminal domain containing protein 0.0481 0.2286 0.9575
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.008 0.0325
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0051 0.0169 0.0259
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0048 0.0155 0.0206
Mycobacterium ulcerans lipase LipD 0.0029 0.0061 0.0057
Echinococcus multilocularis solute carrier family 22 0.005 0.0164 0.0251
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Giardia lamblia Prolyl-tRNA synthetase 0.0107 0.0444 0.1932
Schistosoma mansoni transient receptor potential channel 0.0146 0.0638 0.0988
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0018 0.0003 0.0008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0033 0.008 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0123 0.038
Echinococcus granulosus importin subunit beta 1 0.0066 0.024 0.037
Loa Loa (eye worm) hypothetical protein 0.0033 0.008 0.0238
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0033 0.008 0.0325
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.005 0.0164 0.016
Onchocerca volvulus 0.005 0.0164 0.0462
Echinococcus multilocularis GPCR, family 2 0.005 0.0165 0.0252
Loa Loa (eye worm) isocitrate dehydrogenase 0.0024 0.0037 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.008 0.0325
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0042 0.006
Toxoplasma gondii lysine-tRNA ligase 0.008 0.0309 0.063
Schistosoma mansoni hypothetical protein 0.005 0.0165 0.0252
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0113 0.0474 0.0734
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0064 0.019
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.002 0.0016 0.0056
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0018 0.0004 0.0005
Brugia malayi Cyclin, N-terminal domain containing protein 0.0062 0.0223 0.0924
Leishmania major threonyl-tRNA synthetase, putative 0.002 0.0015 0.0039
Plasmodium falciparum mitogen-activated protein kinase 2 0.058 0.2777 0.3751
Schistosoma mansoni coup transcription factor 0.0033 0.008 0.0121
Giardia lamblia Kinase, CMGC CDK 0.0218 0.0992 0.4332
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.018
Loa Loa (eye worm) hypothetical protein 0.0221 0.1007 0.2984
Giardia lamblia Cyclin B-like protein 0.0062 0.0223 0.0965
Onchocerca volvulus 0.005 0.0164 0.0462
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Brugia malayi Steroid receptor seven-up type 2 0.0033 0.008 0.0325
Onchocerca volvulus 0.005 0.0164 0.0462
Echinococcus multilocularis cyclin dependent kinase 5 0.0218 0.0992 0.154
Leishmania major hypothetical protein, conserved 0.0057 0.0195 0.0596
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0125 0.0531 0.1636
Trichomonas vaginalis sugar transport protein, putative 0.005 0.0164 0.0506
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0024 0.0037 0.0105
Trichomonas vaginalis D-aminoacylase, putative 0.0029 0.0061 0.0188
Loa Loa (eye worm) hypothetical protein 0.0501 0.2388 0.7078
Echinococcus multilocularis cyclin dependent kinase 0.0218 0.0992 0.154
Brugia malayi hypothetical protein 0.005 0.0164 0.0674
Entamoeba histolytica hypothetical protein 0.008 0.0309 0.134
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0107 0.0444 0.1932
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0024 0.0037 0.0053
Entamoeba histolytica Ran family GTPase 0.0048 0.0155 0.0666
Loa Loa (eye worm) hypothetical protein 0.0033 0.008 0.0238
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0033 0.008 0.0121
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0357 0.1675 0.2603
Echinococcus multilocularis neuropeptide s receptor 0.0496 0.2361 0.3673
Brugia malayi Calcitonin receptor-like protein seb-1 0.0159 0.0701 0.2927
Trypanosoma brucei glucose transporter 2A 0.0111 0.0462 0.2009
Echinococcus granulosus lysyl tRNA synthetase 0.008 0.0309 0.0477
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0218 0.0992 0.294
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0462 0.1428
Schistosoma mansoni hypothetical protein 0.0357 0.1675 0.2603
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0107 0.0444 0.1849
Giardia lamblia Hypothetical protein 0.0246 0.113 0.4936
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.012 0.051 0.079
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Trypanosoma cruzi sugar transporter, putative 0.005 0.0164 0.0498
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0024 0.0037 0.0105
Schistosoma mansoni sugar transporter 0.005 0.0164 0.0251
Schistosoma mansoni protein kinase 0.0113 0.0474 0.0734
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0051 0.0169 0.0728
Plasmodium falciparum calcium-dependent protein kinase 4 0.0113 0.0474 0.0638
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.005 0.0164 0.016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0033 0.008 0.0238
Schistosoma mansoni hypothetical protein 0.0062 0.0223 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0049 0.0153
Entamoeba histolytica protein kinase, putative 0.0083 0.0325 0.1412
Trichomonas vaginalis penicillin-binding protein, putative 0.0029 0.0061 0.0188
Trypanosoma cruzi importin beta-1 subunit, putative 0.0053 0.0179 0.0546
Treponema pallidum methylated-DNA-protein-cysteine S-methyltransferase (dat) 0.0673 0.3234 1
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0337 0.1576 0.245
Brugia malayi beta-lactamase 0.0029 0.0061 0.0243
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0086 0.0267
Brugia malayi RNA, U transporter 1 0.0187 0.0837 0.3499
Echinococcus granulosus cyclin A3 4 0.0062 0.0223 0.0343
Loa Loa (eye worm) phosphatidylinositol 3 0.0051 0.0169 0.0501
Onchocerca volvulus 0.005 0.0164 0.0462
Mycobacterium tuberculosis Probable lipase LipE 0.0029 0.0061 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0034 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0065 0.0201
Loa Loa (eye worm) hypothetical protein 0.0087 0.0345 0.1023
Echinococcus multilocularis Cyclin L1 0.0062 0.0223 0.0343
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.113 0.3494
Schistosoma mansoni lamin 0.003 0.0064 0.0095
Plasmodium falciparum proline--tRNA ligase 0.0125 0.0531 0.0715
Brugia malayi Major Facilitator Superfamily protein 0.005 0.0164 0.0674
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Plasmodium vivax threonine--tRNA ligase, putative 0.002 0.0015 0.0017
Leishmania major mitotic cyclin, putative 0.0062 0.0223 0.0682
Echinococcus granulosus solute carrier family 22 0.005 0.0164 0.0251
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0048 0.0155 0.0471
Schistosoma mansoni glycyl-tRNA synthetase 0.002 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0033 0.008 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0049 0.0153
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.008 0.0325
Entamoeba histolytica protein kinase, putative 0.0113 0.0474 0.2064
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.008 0.0325
Trypanosoma brucei glucose transporter, putative 0.0111 0.0462 0.2009
Mycobacterium leprae conserved hypothetical protein 0.0029 0.0061 0.0057
Echinococcus multilocularis solute carrier family 22 0.005 0.0164 0.0251
Brugia malayi Transient-receptor-potential like protein 0.0082 0.0322 0.1338
Trichomonas vaginalis cyclin B, putative 0.0062 0.0223 0.069
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Brugia malayi lysyl-tRNA synthetase 0.008 0.0309 0.1283
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0029 0.0061 0.0057
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.005 0.0164 0.0218
Trichomonas vaginalis serine/threonine kinase, putative 0.0018 0.0003 0.0009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.008 0.0121
Loa Loa (eye worm) hypothetical protein 0.0107 0.0444 0.1316
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0044 0.0132 0.0567
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.002 0.0015 0.0031
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.018
Toxoplasma gondii glycyl-tRNA synthetase 0.002 0.0015 0.0031
Echinococcus multilocularis cyclin A3 4 0.0062 0.0223 0.0343
Echinococcus multilocularis cyclin B 0.0481 0.2286 0.3556
Echinococcus multilocularis short transient receptor potential channel 6 0.0146 0.0638 0.0988
Trypanosoma brucei glucose transporter, putative 0.0111 0.0462 0.2009
Treponema pallidum prolyl-tRNA synthetase 0.0038 0.0103 0.0272
Toxoplasma gondii isocitrate dehydrogenase 0.0024 0.0037 0.0075
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0033 0.008 0.0121
Mycobacterium ulcerans esterase/lipase LipP 0.0029 0.0061 0.0057
Trichomonas vaginalis cyclin B, putative 0.0481 0.2286 0.7071
Trichomonas vaginalis sugar transporter, putative 0.0111 0.0462 0.1428
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0086 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0004 0.0012
Leishmania major importin beta-1 subunit, putative 0.0053 0.0179 0.0546
Echinococcus multilocularis short transient receptor potential channel 6 0.0146 0.0638 0.0988
Loa Loa (eye worm) hypothetical protein 0.0107 0.0444 0.1316
Echinococcus multilocularis cyclin dependent kinase 9 0.0049 0.016 0.0244
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Brugia malayi hypothetical protein 0.005 0.0164 0.0674
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0113 0.0474 0.1405
Echinococcus multilocularis General substrate transporter 0.0306 0.1427 0.2218
Toxoplasma gondii hypothetical protein 0.0184 0.0823 0.1679
Brugia malayi Cyclin, N-terminal domain containing protein 0.0175 0.0779 0.3253
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0068 0.0251 0.0768
Trichomonas vaginalis sugar transporter, putative 0.0111 0.0462 0.1428
Trypanosoma cruzi hexose transporter, putative 0.006 0.0215 0.0655
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0058 0.0086
Schistosoma mansoni intermediate filament proteins 0.003 0.0064 0.0095
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0003 0.0009
Trichomonas vaginalis cyclins, putative 0.0481 0.2286 0.7071
Schistosoma mansoni kinase 0.0049 0.016 0.0244
Plasmodium falciparum cyclin 1 0.0062 0.0223 0.0298
Echinococcus granulosus glycyl tRNA synthetase 0.002 0.0015 0.002
Brugia malayi hypothetical protein 0.0501 0.2388 1
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.002 0.0062
Leishmania major glucose transporter, lmgt3 0.0111 0.0462 0.142
Echinococcus granulosus cyclin B 0.0481 0.2286 0.3556
Loa Loa (eye worm) hypothetical protein 0.0121 0.0515 0.1527
Echinococcus multilocularis lysyl tRNA synthetase 0.008 0.0309 0.0477
Trypanosoma brucei glucose transporter, putative 0.0111 0.0462 0.2009
Loa Loa (eye worm) sugar transporter 0.0357 0.1675 0.4963
Echinococcus multilocularis cyclins 0.0246 0.113 0.1755
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0033 0.008 0.0121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0033 0.008 0.0238
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.008 0.0325
Loa Loa (eye worm) hypothetical protein 0.0072 0.0272 0.0807
Echinococcus multilocularis transient receptor potential gamma protein 0.0221 0.1007 0.1563
Brugia malayi Isocitrate dehydrogenase 0.0024 0.0037 0.0143
Brugia malayi major facilitator superfamily protein 0.005 0.0164 0.0674
Trypanosoma brucei cdc2-related kinase 3 0.0218 0.0992 0.4332
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.002 0.0062
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.008 0.0309 0.134
Onchocerca volvulus Protein CNPPD1 homolog 0.0062 0.0223 0.0729
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trypanosoma cruzi cyclin, putative 0.0481 0.2286 0.7068
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Trichomonas vaginalis esterase, putative 0.0029 0.0061 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0123 0.038
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0164 0.0506
Entamoeba histolytica cyclin family protein 0.0246 0.113 0.4936
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0061 0.018
Loa Loa (eye worm) hypothetical protein 0.003 0.0064 0.019
Entamoeba histolytica protein kinase domain containing protein 0.0049 0.016 0.0687
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0033 0.008 0.0325
Brugia malayi hypothetical protein 0.0062 0.0223 0.0924
Echinococcus granulosus cyclins 0.0246 0.113 0.1755
Onchocerca volvulus 0.005 0.0164 0.0462
Loa Loa (eye worm) cyclin domain-containing protein 0.0062 0.0223 0.0661
Leishmania major lysyl-tRNA synthetase, putative 0.008 0.0309 0.0947
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0058 0.0086
Schistosoma mansoni glucose transport protein 0.0357 0.1675 0.2603
Echinococcus multilocularis neuropeptide receptor A26 0.0496 0.2361 0.3673
Echinococcus multilocularis cyclins 0.0246 0.113 0.1755
Echinococcus multilocularis G1:S specific cyclin D1 0.0062 0.0223 0.0343
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Trypanosoma brucei THT1 - hexose transporter, putative 0.0111 0.0462 0.2009
Echinococcus granulosus cyclin dependent kinase 5 0.0218 0.0992 0.154
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0062 0.0223 0.0661
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0237 0.0365
Mycobacterium ulcerans glycyl-tRNA synthetase 0.002 0.0015 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.002 0.0062
Trypanosoma brucei mitotic cyclin 6 0.0481 0.2286 1
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Plasmodium falciparum importin beta, putative 0.0066 0.024 0.0321
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Schistosoma mansoni hypothetical protein 0.0262 0.1207 0.1875
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.1675 0.5178
Loa Loa (eye worm) hypothetical protein 0.008 0.0309 0.0916
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.058 0.2777 0.3751
Echinococcus multilocularis transient receptor potential ion channel A 0.0214 0.097 0.1507
Trichomonas vaginalis cyclin B, putative 0.0481 0.2286 0.7071
Echinococcus multilocularis cyclins 0.0246 0.113 0.1755
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0042 0.006
Schistosoma mansoni lysyl-tRNA synthetase 0.008 0.0309 0.0477
Plasmodium falciparum lysine--tRNA ligase 0.008 0.0309 0.0414
Trichomonas vaginalis CMGC family protein kinase 0.0018 0.0003 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0325 0.0502
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.005 0.0164 0.016
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Chlamydia trachomatis lysine--tRNA ligase 0.008 0.0309 0.0912
Mycobacterium tuberculosis Conserved protein 0.0029 0.0061 0.0057
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0018 0.0003 0.0009
Giardia lamblia Hypothetical protein 0.0062 0.0223 0.0965
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trypanosoma cruzi hexose transporter, putative 0.0111 0.0462 0.142
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0107 0.0444 0.0687
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0132 0.0409
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0125 0.0531 0.1636
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0074 0.023
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0048 0.0155 0.0666
Echinococcus multilocularis thyroid hormone receptor alpha 0.0033 0.008 0.0121
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.003 0.0042
Trypanosoma brucei glucose transporter 1E 0.0111 0.0462 0.2009
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0165 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0123 0.038
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.008 0.0325
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.005 0.0164 1
Leishmania major hypothetical protein, conserved 0.0018 0.0004 0.0003
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0237 0.0726
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0169 0.0523
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0237 0.0484
Brugia malayi cyclin-dependent kinase 9 0.0049 0.016 0.0658
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0049 0.0153
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.016 0.0244
Echinococcus multilocularis dnaJ subfamily B 0.132 0.6424 1
Trichomonas vaginalis cyclin B, putative 0.0481 0.2286 0.7071
Trichomonas vaginalis sugar transporter, putative 0.005 0.0164 0.0506
Entamoeba histolytica hypothetical protein 0.0062 0.0223 0.0965
Echinococcus multilocularis cyclin t1 0.0062 0.0223 0.0343
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0357 0.1675 0.2603
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0086 0.0266
Echinococcus multilocularis cyclin dependent kinase 1 0.0218 0.0992 0.154
Mycobacterium tuberculosis Probable hydrolase 0.0029 0.0061 0.0057
Schistosoma mansoni transcription factor LCR-F1 0.0026 0.0046 0.0068
Leishmania major glucose transporter, lmgt2 0.0111 0.0462 0.142
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0474 0.0734
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0049 0.0153
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0165 0.0679
Brugia malayi Cyclin, N-terminal domain containing protein 0.0337 0.1576 0.6595
Brugia malayi major facilitator superfamily protein 0.005 0.0164 0.0674
Trypanosoma cruzi cdc2-related kinase 3 0.0218 0.0992 0.3062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0169 0.0523
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0357 0.1675 0.2603
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0113 0.0474 0.0734
Echinococcus multilocularis muscleblind protein 1 0.0121 0.0515 0.0798
Trichomonas vaginalis penicillin-binding protein, putative 0.0029 0.0061 0.0188
Brugia malayi hypothetical protein 0.005 0.0164 0.0674
Trichomonas vaginalis cyclin B, putative 0.0062 0.0223 0.069
Entamoeba histolytica hypothetical protein 0.0054 0.0185 0.0799
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0033 0.008 0.0325
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0164 0.0506
Echinococcus multilocularis cyclin dependent kinase 1 0.0218 0.0992 0.154
Echinococcus multilocularis FTZ F1 alpha 0.0033 0.008 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0223 0.069
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0033 0.008 0.0121
Entamoeba histolytica hypothetical protein 0.0053 0.0179 0.0772
Trichomonas vaginalis cyclin D, putative 0.0246 0.113 0.3494
Schistosoma mansoni glucose transport protein 0.0357 0.1675 0.2603
Trichomonas vaginalis ran, putative 0.0048 0.0155 0.0479
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0123 0.038
Loa Loa (eye worm) hypothetical protein 0.005 0.0164 0.0485
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0048 0.0155 0.0316
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.0992 0.154
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0029 0.0061 0.009
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.008 0.0309 0.0955
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0024 0.0037 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0003 0.0009
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0051 0.0169 0.0259
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0018 0.0004 0.0008
Echinococcus granulosus solute carrier family 22 0.005 0.0164 0.0251
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0033 0.008 0.0238
Trypanosoma cruzi CYC2-like cyclin, putative 0.0481 0.2286 0.7068
Trichomonas vaginalis conserved hypothetical protein 0.0111 0.0462 0.1428
Brugia malayi Cyclin C 0.012 0.051 0.2126
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Brugia malayi nuclear hormone receptor 0.0033 0.008 0.0325
Brugia malayi latrophilin 2 splice variant baaae 0.0109 0.0453 0.1887
Loa Loa (eye worm) hypothetical protein 0.0066 0.024 0.0712
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0024 0.0037 0.0053
Loa Loa (eye worm) hypothetical protein 0.0481 0.2286 0.6777
Trichomonas vaginalis cyclins, putative 0.0481 0.2286 0.7071
Plasmodium falciparum ataxin-2 like protein, putative 0.0057 0.0195 0.026
Schistosoma mansoni nuclear hormone receptor 0.0033 0.008 0.0121
Plasmodium falciparum protein kinase 7 0.1011 0.4903 0.6627
Mycobacterium ulcerans methylated-DNA--protein-cysteine methyltransferase Ogt 0.2045 1 1
Trichomonas vaginalis cyclin A, putative 0.0481 0.2286 0.7071
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.018
Leishmania major protein kinase, putative 0.0113 0.0474 0.1459
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0068 0.0251 0.0768
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0023 0.0031 0.0122
Echinococcus granulosus intermediate filament protein 0.003 0.0064 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0018 0.0003 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0003 0.0009

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 11 % Activity expressed as percent inhibition of anti-TNP IgM level in TNP-LPS immunized mice, at a dose of 10 mg/kg perorally ChEMBL. 12161149
Inhibition (functional) = 11 % Activity expressed as percent inhibition of anti-TNP IgM level in TNP-LPS immunized mice, at a dose of 10 mg/kg perorally ChEMBL. 12161149

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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