Detailed information for compound 1359315

Basic information

Technical information
  • TDR Targets ID: 1359315
  • Name: K788-9905
  • MW: 603.042 | Formula: C31H23ClN2O7S
  • H donors: 2 H acceptors: 5 LogP: 5.28 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)c1cc(cc(c1)C(=O)OC)NC(=O)c1ccc2c(c1)N(Cc1cccc(c1)Cl)C(=O)c1c([S+]2[O-])cccc1
  • InChi: 1S/C31H23ClN2O7S/c1-40-30(37)20-13-21(31(38)41-2)15-23(14-20)33-28(35)19-10-11-27-25(16-19)34(17-18-6-5-7-22(32)12-18)29(36)24-8-3-4-9-26(24)42(27)39/h3-16H,17H2,1-2H3,(H,33,35)
  • InChiKey: SOVFLQIABMZEGM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • NCGC00140442-01

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0229 0.6141
Loa Loa (eye worm) hypothetical protein 0.004 0.0164 0.0365
Brugia malayi nuclear receptor NHR-88 0.0017 0.0019 0.0041
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0019 0.0011
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.003 0.0079
Echinococcus granulosus serotonin receptor 0.0032 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0195
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0412 0.0902
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0021 0.0045 0.01
Echinococcus multilocularis dna polymerase kappa 0.0019 0.003 0.0023
Trypanosoma brucei unspecified product 0.0019 0.003 0.0811
Schistosoma mansoni RAR-like nuclear receptor 0.0017 0.0019 0.0024
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0244 0.0544
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.011 0.0229
Plasmodium vivax calpain, putative 0.0021 0.0039 0.0782
Brugia malayi Dopamine receptor 0.0032 0.011 0.0246
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0017 0.0019 0.0011
Loa Loa (eye worm) hypothetical protein 0.0718 0.4488 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0032 0.011 0.0103
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Brugia malayi Smad1 0.0016 0.001 0.0023
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.011 0.0229
Echinococcus multilocularis hypothetical protein 0.0021 0.0039 0.0032
Toxoplasma gondii ABC1 family protein 0.0073 0.0373 0.9041
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0039 0.1055
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0031 0.0068
Trypanosoma brucei lanosterol synthase 0.0063 0.0311 0.8336
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0032 0.011 0.0246
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0028 0.0087 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0017 0.0019 0.0041
Brugia malayi beta-lactamase family protein 0.0073 0.0373 0.0831
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.003 0.0811
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0015 0.0033
Onchocerca volvulus 0.0073 0.0373 0.0793
Brugia malayi Cell death protein 3 precursor 0.0212 0.126 0.2806
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0019 0.0041
Onchocerca volvulus Cell death protein 3 homolog 0.0212 0.126 0.2776
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0229 0.6141
Onchocerca volvulus 0.0032 0.011 0.0205
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0016 0.0008 0.029
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.1107 0.11
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0019 0.0024
Echinococcus granulosus calpain A 0.0057 0.0271 0.0588
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0017 0.0019 0.0041
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0195
Echinococcus multilocularis GPCR, family 2 0.0017 0.0015 0.0007
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0039 0.1055
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0019 0.0024
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0373 0.1273
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0039 0.1055
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0008 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.011 0.0229
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.015 0.0334
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0032 0.011 0.0103
Brugia malayi beta-lactamase family protein 0.0073 0.0373 0.0831
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.003 0.0811
Schistosoma mansoni opsin-like receptor 0.0032 0.011 0.0229
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0039 0.1055
Schistosoma mansoni neuropeptide receptor 0.0032 0.011 0.0229
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0373 0.0831
Echinococcus multilocularis calpain 0.0021 0.0039 0.0032
Schistosoma mansoni growth hormone secretagogue receptor 0.0032 0.011 0.0229
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0087 0.0195
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.011 0.0229
Schistosoma mansoni Mername-AA248 (C02 family) 0.0021 0.0039 0.0071
Schistosoma mansoni hypothetical protein 0.0718 0.4488 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.015 0.3132
Echinococcus multilocularis dnaJ subfamily B 0.0433 0.267 0.2664
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.003 0.061
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0041
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.011 0.0229
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.1107 0.2453
Echinococcus granulosus orexin receptor type 2 0.0032 0.011 0.0229
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0266 0.1602 0.3559
Loa Loa (eye worm) hypothetical protein 0.0212 0.126 0.2806
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Echinococcus granulosus 7tm_1 domain containing protein 0.0032 0.011 0.0229
Onchocerca volvulus 0.0034 0.0125 0.0237
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.1107 0.2453
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0032 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0718 0.4488 1
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0019 0.0041
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0058 0.0275 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0195
Echinococcus granulosus Smad4 0.0016 0.001 0.0006
Echinococcus multilocularis expressed protein 0.0019 0.0031 0.0023
Brugia malayi prostaglandin transporter 0.0028 0.0087 0.0195
Schistosoma mansoni hypothetical protein 0.0032 0.011 0.0229
Schistosoma mansoni amine GPCR 0.0032 0.011 0.0229
Brugia malayi hypothetical protein 0.0032 0.011 0.0246
Echinococcus multilocularis G protein coupled receptor 139 0.0032 0.011 0.0103
Brugia malayi Dopamine receptor protein 1 0.0032 0.011 0.0246
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0016 0.0008 0.0001
Onchocerca volvulus 0.0032 0.011 0.0205
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0073 0.0373 0.0831
Toxoplasma gondii exonuclease III APE 0.0038 0.015 0.3515
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.0039 0.0071
Giardia lamblia Rab geranylgeranyltransferase 0.0021 0.0045 0.1377
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.015 0.4015
Echinococcus multilocularis sex peptide receptor 0.0032 0.011 0.0103
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.003 0.061
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0019 0.0041
Loa Loa (eye worm) hypothetical protein 0.0073 0.0373 0.0831
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0045 0.1201
Loa Loa (eye worm) hypothetical protein 0.0073 0.0373 0.0831
Brugia malayi putative neuropeptide receptor NPR1 0.0032 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0048 0.0216 0.0481
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0021 0.0045 0.1201
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.015 0.4015
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0058 0.0275 0.0613
Schistosoma mansoni caspase-7 (C14 family) 0.0212 0.126 0.2794
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0167 0.0355
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0067
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.011 0.0246
Trypanosoma cruzi lanosterol synthase, putative 0.0063 0.0311 0.8336
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0017 0.0019 0.0024
Schistosoma mansoni follistatin 0.0019 0.0031 0.0051
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0028 0.0087 0.008
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0373 0.0366
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Schistosoma mansoni organic anion transporter 0.0028 0.0087 0.0178
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0373 0.1273
Brugia malayi isocitrate dehydrogenase 0.0016 0.0008 0.0017
Loa Loa (eye worm) hypothetical protein 0.0073 0.0373 0.0831
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0008 0.0207
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.003 0.0811
Echinococcus granulosus G protein coupled receptor 139 0.0032 0.011 0.0229
Onchocerca volvulus 0.0047 0.021 0.0427
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.003 0.0811
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0102 0.0228
Brugia malayi hypothetical protein 0.0032 0.011 0.0246
Onchocerca volvulus 0.0028 0.0087 0.0154
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.003 0.0067
Trypanosoma cruzi MFS transporter, putative 0.0028 0.0087 0.2344
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0063 0.0311 0.1057
Echinococcus granulosus fmrfamide receptor 0.0032 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0041
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0032 0.011 0.0229
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.003 0.0811
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0373 0.8825
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0021 0.0045 0.0037
Brugia malayi hypothetical protein 0.0032 0.011 0.0246
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0232 0.1385 0.3086
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0032 0.011 0.0229
Schistosoma mansoni amine GPCR 0.0032 0.011 0.0229
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.011 0.0229
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0087 0.0154
Schistosoma mansoni biogenic amine receptor 0.0032 0.011 0.0229
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0031 0.0567
Brugia malayi MH2 domain containing protein 0.0016 0.001 0.0023
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0016 0.0008 0.0214
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0015 0.0007
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0238 0.0804
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.01
Schistosoma mansoni hypothetical protein 0.0023 0.0052 0.0099
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0032 0.011 0.0229
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0229 0.5478
Brugia malayi neuropeptide F receptor 0.0032 0.011 0.0246
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.011 0.0229
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0244 0.0544
Echinococcus multilocularis neuropeptide receptor A26 0.0505 0.3126 0.3121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0017 0.0019 0.0041
Onchocerca volvulus 0.0073 0.0373 0.0793
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.015 0.0142
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.011 0.0229
Echinococcus multilocularis g protein coupled receptor 0.0032 0.011 0.0103
Echinococcus multilocularis thyroid hormone receptor alpha 0.0017 0.0019 0.0011
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.003 0.0067
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.011 0.0229
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0032 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.0149 0.0858 0.1911
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0058 0.0275 0.0268
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.003 0.0811
Brugia malayi hypothetical protein 0.0032 0.0115 0.0257
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.011 0.0103
Echinococcus granulosus ecdysone induced protein 78C 0.0017 0.0019 0.0024
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0016 0.0008 0.0214
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.003 0.0811
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0016 0.0008 0.0018
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0021 0.0045 0.0918
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0238 0.0231
Loa Loa (eye worm) hypothetical protein 0.0073 0.0373 0.0831
Echinococcus multilocularis calpain family protein 1, d 0.004 0.0164 0.0156
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0028 0.0087 0.0195
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Onchocerca volvulus 0.0032 0.011 0.0205
Onchocerca volvulus 0.0032 0.011 0.0205
Echinococcus multilocularis fmrfamide receptor 0.0032 0.011 0.0103
Echinococcus granulosus Solute carrier organic anion transporter family 0.0028 0.0087 0.0178
Echinococcus granulosus neuropeptide receptor A26 0.0505 0.3126 0.696
Echinococcus multilocularis G-protein coupled receptor, putative 0.0032 0.011 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0019 0.0041
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0039 0.1055
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0229 0.5478
Brugia malayi hypothetical protein 0.005 0.0229 0.051
Loa Loa (eye worm) hypothetical protein 0.0034 0.0125 0.0277
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0373 0.1273
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0373 0.8984
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0021 0.0045 0.1009
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0256 0.1541 0.3433
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0373 1
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0016 0.0008 0.0001
Echinococcus multilocularis cpg binding protein 0.0032 0.0113 0.0106
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0373 0.1273
Brugia malayi hypothetical protein 0.0212 0.126 0.2806
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0266 0.1602 0.3559
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0032 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.003 0.0079
Echinococcus multilocularis Smad4 0.0016 0.001 0.0003
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0017 0.0019 0.0024
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0412 1
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0015 0.0033
Schistosoma mansoni hypothetical protein 0.0212 0.126 0.2794
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.011 0.0229
Brugia malayi Melatonin receptor type 1A 0.0032 0.011 0.0246
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.0039 0.0071
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Echinococcus granulosus 7TM GPCR rhodopsin 0.0032 0.011 0.0229
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0412 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0032 0.011 0.0103
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.011 0.0103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0017 0.0019 0.0041
Loa Loa (eye worm) melatonin receptor type 1A 0.0032 0.011 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0017 0.0019 0.0041
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0021 0.0045 0.1009
Onchocerca volvulus 0.0032 0.011 0.0205
Schistosoma mansoni Smad4 0.0016 0.001 0.0006
Toxoplasma gondii transporter, major facilitator family protein 0.0028 0.0087 0.1972
Brugia malayi GnHR receptor homolog 0.0032 0.011 0.0246
Echinococcus multilocularis orexin receptor type 2 0.0032 0.011 0.0103
Schistosoma mansoni hypothetical protein 0.0032 0.011 0.0229
Loa Loa (eye worm) calpain 0.0021 0.0039 0.0088
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.011 0.0103
Schistosoma mansoni neuropeptide receptor 0.0032 0.011 0.0229
Schistosoma mansoni histamine h1 receptor 0.0032 0.011 0.0229
Echinococcus multilocularis serotonin receptor 0.0032 0.011 0.0103
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0229 0.5478
Brugia malayi RE15519p 0.0032 0.011 0.0246
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0057 0.0271 0.0588
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.011 0.0229
Loa Loa (eye worm) calpain family protein 1 0.004 0.0164 0.0365
Schistosoma mansoni adenoreceptor 0.0032 0.011 0.0229
Echinococcus multilocularis smad 0.0016 0.001 0.0003
Schistosoma mansoni myosin xvIII 0.0032 0.011 0.0229
Echinococcus granulosus cpg binding protein 0.0032 0.0113 0.0236
Echinococcus multilocularis serotonin receptor 0.0032 0.011 0.0103
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0238 0.0515
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0021 0.0045 0.0037
Brugia malayi hypothetical protein 0.0032 0.011 0.0246
Echinococcus granulosus neuropeptide FF receptor 2 0.0032 0.011 0.0229
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0373 0.1273
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0021 0.0045 0.1627
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0039 0.1055
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0032 0.011 0.0246
Leishmania major lanosterol synthase, putative 0.0048 0.0211 0.5668
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0057 0.0271 0.0588
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.001 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0017 0.0019 0.0041
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0057 0.0271 0.0264
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0016
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Echinococcus granulosus dnaJ subfamily B 0.0433 0.267 0.5942
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.003 0.0811
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0021 0.0045 0.0083
Echinococcus granulosus sex peptide receptor 0.0032 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.015 0.3515
Brugia malayi G protein-coupled receptor F59B2.13 0.0032 0.011 0.0246
Brugia malayi beta-lactamase 0.0073 0.0373 0.0831
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.003 0.0811
Schistosoma mansoni hypothetical protein 0.0032 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0041
Brugia malayi hypothetical protein 0.0032 0.011 0.0246
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.003 0.0811
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0019 0.0011
Echinococcus granulosus alpha 1A adrenergic receptor 0.0032 0.011 0.0229
Brugia malayi ORL1-like opioid receptor 0.0032 0.011 0.0246
Brugia malayi G-protein coupled receptor 0.0032 0.011 0.0246
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0017 0.0019 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.003 0.0811
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0032 0.011 0.0246
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0006
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0019 0.0024
Echinococcus multilocularis max protein X 0.0466 0.2883 0.2878
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0054 0.0255 0.0569
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0021 0.0045 0.01
Loa Loa (eye worm) TYRA-2 protein 0.0032 0.011 0.0246
Brugia malayi calpain 7 0.0021 0.0039 0.0088
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0058 0.0275 0.6623
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.011 0.0229
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0031 0.0068
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Brugia malayi steroid hormone receptor 0.0017 0.0019 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.011 0.0103
Schistosoma mansoni cpg binding protein 0.0032 0.0113 0.0236
Schistosoma mansoni coup transcription factor 0.0017 0.0019 0.0024
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0373 0.9041
Onchocerca volvulus 0.0019 0.0031 0.0027
Schistosoma mansoni hypothetical protein 0.0047 0.021 0.0451
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0373 0.8984
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0087 0.0195
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.011 0.0229
Echinococcus multilocularis somatostatin receptor 0.0032 0.011 0.0103
Loa Loa (eye worm) hypothetical protein 0.0036 0.0138 0.0308
Echinococcus granulosus g protein coupled receptor 0.0032 0.011 0.0229
Onchocerca volvulus 0.0032 0.011 0.0205
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0016
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0021 0.0045 0.1009
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0016 0.0008 0.0006
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.032 0.0696
Brugia malayi Tachykinin-like peptides receptor 99D 0.0032 0.011 0.0246
Brugia malayi hypothetical protein 0.0032 0.011 0.0246
Echinococcus granulosus GPCR family 2 0.0017 0.0015 0.0016
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.0031 0.0068
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0718 0.4488 1
Schistosoma mansoni cpg binding protein 0.0032 0.0113 0.0236
Onchocerca volvulus Neuropeptide F receptor homolog 0.0032 0.011 0.0205
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0021 0.0039 0.1055
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0041
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0016 0.0008 0.0018
Echinococcus granulosus dro:myosuppressin receptor 0.0032 0.011 0.0229
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0058 0.0275 0.7324
Leishmania major DNA polymerase eta, putative 0.0019 0.003 0.0811
Echinococcus multilocularis fmrfamide receptor 0.0032 0.011 0.0103
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0039 0.1055
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.003 0.0811
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0058 0.0275 0.7324
Schistosoma mansoni ap endonuclease 0.0038 0.015 0.0317
Brugia malayi hypothetical protein 0.0032 0.011 0.0246
Echinococcus multilocularis dna polymerase eta 0.0019 0.003 0.0023
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.015 0.3884
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0373 1
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0021 0.0045 0.1009
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0052 0.0099
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0021 0.0045 0.0918
Echinococcus granulosus tm gpcr rhodopsin 0.0552 0.3432 0.7642
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0017 0.0019 0.0041
Schistosoma mansoni opsin-like receptor 0.0032 0.011 0.0229
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.011 0.0229
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0021 0.0045 0.01
Toxoplasma gondii protease inhibitor PI2 0.0019 0.0031 0.0567
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0017 0.0019 0.0024
Loa Loa (eye worm) transcription factor SMAD2 0.0235 0.1404 0.3128
Echinococcus multilocularis neuropeptide receptor 0.0032 0.011 0.0103
Echinococcus multilocularis neuropeptide FF receptor 2 0.0032 0.011 0.0103
Echinococcus granulosus g protein coupled receptor 0.0032 0.011 0.0229
Echinococcus granulosus dna polymerase kappa 0.0019 0.003 0.005
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0032 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Schistosoma mansoni hypothetical protein 0.0051 0.0235 0.0508
Schistosoma mansoni steroid hormone receptor ad4bp 0.0017 0.0019 0.0024
Giardia lamblia Prenyltransferase 0.0058 0.0275 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0276 0.6636
Onchocerca volvulus 0.0028 0.0087 0.0154
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0214
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0041
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.0031 0.0068
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0021 0.0045 0.0918
Schistosoma mansoni amine GPCR 0.0032 0.011 0.0229
Trypanosoma cruzi protein farnesyltransferase, putative 0.0058 0.0275 0.7381
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.1107 0.2453
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.011 0.0246
Schistosoma mansoni smad1 5 8 and 0.0016 0.001 0.0006
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.001 0.0006
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0466 0.2883 0.6424
Echinococcus granulosus g protein coupled receptor 0.0032 0.011 0.0229
Schistosoma mansoni hypothetical protein 0.0032 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.011 0.0103
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.003 0.0811
Brugia malayi Serotonin receptor 0.0032 0.011 0.0246
Echinococcus granulosus apoptotic protease activating factor 1 0.0212 0.126 0.2794
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0016 0.0008 0.0006
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0058 0.0275 0.6623
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0058 0.0275 0.0613
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0021 0.0045 0.1201
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.011 0.0103
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.1385 0.1378
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Schistosoma mansoni neuropeptide receptor 0.0032 0.011 0.0229
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0058 0.0275 0.7324
Giardia lamblia DINP protein human, muc B family 0.0019 0.003 0.0833
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0017 0.0019 0.0041
Echinococcus granulosus tachykinin peptides receptor 99D 0.0032 0.011 0.0229
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.011 0.0229
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.003 0.0023
Onchocerca volvulus 0.0149 0.0858 0.1878
Schistosoma mansoni DNA polymerase eta 0.0019 0.003 0.005
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0032 0.011 0.0103
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.015 0.4015
Schistosoma mansoni alpha-1 adrenergic receptor 0.0032 0.011 0.0229
Onchocerca volvulus 0.003 0.0102 0.0187
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0412 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0031 0.0567
Onchocerca volvulus Deterin homolog 0.0718 0.4488 1
Echinococcus multilocularis apoptotic protease activating factor 1 0.0212 0.126 0.1253
Onchocerca volvulus 0.0032 0.011 0.0205
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.003 0.0811
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0032 0.011 0.0229
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.011 0.0229
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0017 0.0019 0.0011
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.011 0.0246
Echinococcus multilocularis calpain 7 (C02 family) 0.0021 0.0039 0.0032
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.011 0.0246
Echinococcus granulosus g-protein coupled receptor 0.0032 0.011 0.0229
Schistosoma mansoni hypothetical protein 0.0684 0.4267 0.9507
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0238 0.0804
Brugia malayi Dopamine receptor protein 2 0.0032 0.011 0.0246
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.015 0.0495
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.001 0.0006
Echinococcus granulosus agrin 0.0019 0.0031 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.003 0.0811
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0015 0.0016
Leishmania major geranylgeranyltransferase, putative 0.0016 0.0008 0.0214
Toxoplasma gondii hypothetical protein 0.0027 0.0082 0.1835
Echinococcus granulosus geminin 0.0684 0.4267 0.9507
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.011 0.0103
Echinococcus multilocularis caspase 2 0.0212 0.126 0.1253
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0032 0.011 0.0246
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0552 0.3432 0.3427
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0373 1
Brugia malayi CXXC zinc finger family protein 0.003 0.0102 0.0228
Echinococcus granulosus somatostatin receptor 0.0032 0.011 0.0229
Echinococcus granulosus FTZ F1 alpha 0.0017 0.0019 0.0024
Echinococcus multilocularis agrin 0.0019 0.0031 0.0023
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Brugia malayi hypothetical protein 0.0032 0.011 0.0246
Brugia malayi putative neuropeptide receptor 0.0032 0.011 0.0246
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0373 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0373 0.0815
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0039 0.1055
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0021 0.0045 0.0083
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.015 0.2058
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0021 0.0045 0.1201
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.015 0.3884
Echinococcus granulosus calpain 0.0021 0.0039 0.0071
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0021 0.0045 0.1201
Brugia malayi Steroid receptor seven-up type 2 0.0017 0.0019 0.0041
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0082 0.1835
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0015 0.0007
Toxoplasma gondii hypothetical protein 0.0021 0.0045 0.0918
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0045 0.1201
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0019 0.0041
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0021 0.0045 0.0083
Brugia malayi neuropeptide F receptor 0.0032 0.011 0.0246
Echinococcus multilocularis FTZ F1 alpha 0.0017 0.0019 0.0011
Brugia malayi MH1 domain containing protein 0.0016 0.001 0.0023
Echinococcus multilocularis g protein coupled receptor 0.0032 0.011 0.0103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0017 0.0019 0.0041
Onchocerca volvulus 0.0032 0.011 0.0205
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Onchocerca volvulus 0.0032 0.011 0.0205
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0032 0.011 0.0246
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0021 0.0045 0.1627
Onchocerca volvulus 0.0028 0.0087 0.0154
Onchocerca volvulus 0.0028 0.0087 0.0154
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.015 0.0334
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0031 0.0567
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0039 0.1055
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.1385 0.3074
Brugia malayi hypothetical protein 0.0032 0.011 0.0246
Schistosoma mansoni neuropeptide f receptor 76f 0.0032 0.011 0.0229
Schistosoma mansoni hypothetical protein 0.0433 0.267 0.5942
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0373 0.0815
Mycobacterium ulcerans beta-lactamase 0.0073 0.0373 0.8984
Mycobacterium ulcerans hypothetical protein 0.0073 0.0373 0.8984
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0016 0.0008 0.0001
Mycobacterium tuberculosis Conserved protein 0.0073 0.0373 0.1273
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0039 0.1055
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.003 0.005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0018
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0031 0.0567
Echinococcus multilocularis g-protein coupled receptor 0.0032 0.011 0.0103
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0188 0.1107 0.2466
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.003 0.0811
Echinococcus multilocularis neuropeptide receptor 0.0032 0.011 0.0103
Onchocerca volvulus 0.0032 0.011 0.0205
Schistosoma mansoni retinoic acid receptor RXR 0.0017 0.0019 0.0024
Brugia malayi SPARC precursor 0.0019 0.0031 0.0068
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0021 0.0045 0.1201
Brugia malayi larval opioid receptor 0.0032 0.011 0.0246
Echinococcus granulosus caspase 2 0.0212 0.126 0.2794
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.011 0.0229
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.003 0.0811
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0229 0.5478
Brugia malayi Probable ClpP-like protease 0.0079 0.0412 0.0917
Schistosoma mansoni opsin-like receptor 0.0032 0.011 0.0229
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0016 0.0008 0.0018
Onchocerca volvulus 0.0718 0.4488 1
Schistosoma mansoni calpain (C02 family) 0.0021 0.0039 0.0071
Brugia malayi G-protein coupled receptor 0.0032 0.011 0.0246
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.001 0.0006
Echinococcus granulosus hypothetical protein 0.0032 0.011 0.0229
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0008 0.0207
Brugia malayi ecdysteroid receptor 0.0017 0.0019 0.0041
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.011 0.0229
Onchocerca volvulus 0.0032 0.011 0.0205
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0058 0.0275 0.7381
Onchocerca volvulus 0.0032 0.011 0.0205
Echinococcus granulosus max protein X 0.0466 0.2883 0.6417
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0087 0.0154
Echinococcus granulosus calpain 7 C02 family 0.0021 0.0039 0.0071
Schistosoma mansoni amine GPCR 0.0032 0.011 0.0229
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0008 0.0207
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.011 0.0229
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0373 0.1273
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.021 0.0467
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0195
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0032 0.011 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0017 0.0019 0.0041
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.011 0.0229
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.015 0.3515
Giardia lamblia Rab geranylgeranyltransferase 0.0021 0.0045 0.1377
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0373 0.0815
Brugia malayi photoreceptor-specific nuclear receptor 0.0017 0.0019 0.0041
Brugia malayi Serotonin receptor 0.0032 0.011 0.0246
Brugia malayi hypothetical protein 0.0028 0.0087 0.0195
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.001 0.0023
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.011 0.0229
Leishmania major DNA polymerase kappa, putative 0.0019 0.003 0.0811
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.003 0.005
Schistosoma mansoni bhlhzip transcription factor bigmax 0.0466 0.2883 0.6417
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0017 0.0019 0.0024
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0021 0.0045 0.01
Echinococcus granulosus neuropeptide receptor 0.0032 0.011 0.0229
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0008 0.0207
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.015 0.5439
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0718 0.4488 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0238 0.4744
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0039 0.1055
Onchocerca volvulus 0.0073 0.0373 0.0793
Brugia malayi AKH receptor 0.0032 0.011 0.0246
Brugia malayi hypothetical protein 0.0032 0.011 0.0246
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.011 0.0229
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0057 0.0271 0.0588
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.015 0.4015
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0017 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0008 0.0214
Brugia malayi MH1 domain containing protein 0.0016 0.001 0.0023
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.1107 0.2453
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0058 0.0275 0.0597
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.011 0.0229
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0412 0.5
Schistosoma mansoni smad 0.0016 0.001 0.0006
Brugia malayi MH2 domain containing protein 0.0235 0.1404 0.3128
Brugia malayi calpain family protein 1 0.0054 0.0255 0.0569
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0021 0.0045 0.1201
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0412 1
Loa Loa (eye worm) beta-lactamase 0.0073 0.0373 0.0831
Schistosoma mansoni hypothetical protein 0.0684 0.4267 0.9507
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0718 0.4488 1
Echinococcus granulosus follistatin 0.0019 0.0031 0.0051
Loa Loa (eye worm) hypothetical protein 0.0073 0.0373 0.0831
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.011 0.0103
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0032 0.011 0.0103
Onchocerca volvulus 0.0032 0.011 0.0205
Trypanosoma cruzi lanosterol synthase, putative 0.0063 0.0311 0.8336
Brugia malayi follicle stimulating hormone receptor 0.0256 0.1541 0.3433
Leishmania major hypothetical protein, conserved 0.0073 0.0373 1
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0008 0.0017
Echinococcus granulosus allatostatin A receptor 0.0032 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.005 0.0229 0.051
Onchocerca volvulus 0.0028 0.0087 0.0154
Loa Loa (eye worm) MH2 domain-containing protein 0.0235 0.1404 0.3128
Echinococcus granulosus neuropeptide receptor 0.0032 0.011 0.0229
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.011 0.0103
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.015 0.5303
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0019 0.0041
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0021 0.0045 0.1201
Trichomonas vaginalis esterase, putative 0.0073 0.0373 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0412 1
Echinococcus multilocularis neuropeptide s receptor 0.0505 0.3126 0.3121
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0412 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0032 0.011 0.0229
Schistosoma mansoni inhibitor of apoptosis protein 0.0718 0.4488 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.011 0.0103
Loa Loa (eye worm) hypothetical protein 0.0079 0.0412 0.0917
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0016 0.0008 0.0006
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.011 0.0103
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0016 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Mycobacterium tuberculosis Conserved protein 0.0073 0.0373 0.1273
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0244 0.0544
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0032 0.011 0.0229
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0412 1
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0058 0.0275 0.7324
Brugia malayi nuclear hormone receptor 0.0017 0.0019 0.0041
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0019 0.0024
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0412 1
Brugia malayi hypothetical protein 0.0232 0.1385 0.3086
Echinococcus multilocularis ecdysone induced protein 78C 0.0017 0.0019 0.0011
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Schistosoma mansoni survival motor neuron protein 0.0047 0.021 0.0451
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0032 0.011 0.0103
Mycobacterium tuberculosis Conserved protein 0.0073 0.0373 0.1273
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.003 0.0811
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.011 0.0229
Leishmania major hypothetical protein, conserved 0.005 0.0229 0.6141
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0058 0.0275 0.7324
Schistosoma mansoni calpain C (C02 family) 0.0021 0.0039 0.0071
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0229 0.6141
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0017 0.0019 0.0041
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0017 0.0019 0.0024
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0412 0.0902
Brugia malayi calpain family protein 1 0.0054 0.0255 0.0569
Echinococcus granulosus smad 0.0016 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0068
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0032 0.011 0.0229
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0373 1
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0039 0.1055
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0039 0.1055
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0019 0.0024
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.011 0.0229
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.003 0.0067
Brugia malayi MH2 domain containing protein 0.0016 0.001 0.0023
Loa Loa (eye worm) Smad1 0.0016 0.001 0.0023
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0373 0.0831
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0017 0.0019 0.0024
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0373 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Echinococcus granulosus inhibitor of apoptosis protein 0.0718 0.4488 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0412 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0017 0.0019 0.0024
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0052 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0068
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0033
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.011 0.0103
Schistosoma mansoni biogenic amine receptor 0.0032 0.011 0.0229
Trypanosoma brucei antigen, putative 0.0021 0.0039 0.1055
Onchocerca volvulus 0.0032 0.011 0.0205
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0028 0.0087 0.0178
Echinococcus multilocularis inhibitor of apoptosis protein 0.0718 0.4488 0.4484
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0058 0.0275 0.7324
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.003 0.0811
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0021 0.0045 0.0037
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0008 0.0207
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0015 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0017 0.0019 0.0041
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0021 0.0045 0.0918
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.1107 0.2453
Onchocerca volvulus 0.0212 0.126 0.2776
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0058 0.0275 0.0597
Echinococcus granulosus calpain 5 0.0021 0.0039 0.0071
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0054 0.0255 0.0553
Onchocerca volvulus 0.0021 0.0045 0.0059
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0017 0.0019 0.0041
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.011 0.0229
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.011 0.0103
Loa Loa (eye worm) calpain family protein 1 0.0054 0.0255 0.0569
Onchocerca volvulus 0.0032 0.011 0.0205
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0082 0.1835
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0039 0.1055
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0058 0.0275 0.6623
Brugia malayi hypothetical protein 0.0028 0.0087 0.0195
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.011 0.0229
Schistosoma mansoni cpg binding protein 0.003 0.0102 0.0211
Brugia malayi G protein-coupled receptor 0.0032 0.011 0.0246
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0138 0.0308
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0718 0.4488 0.4484
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0718 0.4488 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0021 0.0039 0.1055
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0373 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0068
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0032 0.011 0.0229
Plasmodium falciparum geranylgeranyltransferase, putative 0.0016 0.0008 0.0006
Schistosoma mansoni agrin 0.0019 0.0031 0.0051
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0032 0.011 0.0103
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0373 0.1273
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0032 0.011 0.0103
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0188 0.1107 0.2466
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.011 0.0229
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0019 0.0041
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0087 0.0154
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0017 0.0019 0.0041
Schistosoma mansoni amine GPCR 0.0032 0.011 0.0229
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0266 0.1602 0.1596
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.003 0.1099
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0466 0.2883 0.6424
Loa Loa (eye worm) hypothetical protein 0.0053 0.0244 0.0544
Echinococcus multilocularis calpain 5 0.0021 0.0039 0.0032
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0017 0.0019 0.0011
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0373 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0032 0.011 0.0229
Echinococcus granulosus neuropeptide s receptor 0.0505 0.3126 0.696
Brugia malayi hypothetical protein 0.0149 0.0858 0.1911
Echinococcus multilocularis allatostatin A receptor 0.0032 0.011 0.0103
Mycobacterium ulcerans lipase LipD 0.0073 0.0373 0.8984
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0195
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.011 0.0103
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.1107 0.11
Onchocerca volvulus 0.0032 0.011 0.0205
Plasmodium vivax geranylgeranyltransferase, putative 0.0016 0.0008 0.0006
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0045 0.1201
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.011 0.0229
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0039 0.1055
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.011 0.0103
Echinococcus multilocularis g protein coupled receptor 0.0032 0.011 0.0103
Echinococcus multilocularis follistatin 0.0019 0.0031 0.0023
Echinococcus multilocularis geminin 0.0684 0.4267 0.4263
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0017 0.0019 0.0024
Echinococcus granulosus calpain A 0.0021 0.0039 0.0071
Schistosoma mansoni ap endonuclease 0.0038 0.015 0.0317
Schistosoma mansoni organic anion transporter 0.0028 0.0087 0.0178
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0195
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0016 0.0008 0.029
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0016 0.0008 0.0001
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.003 0.0811
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0087 0.0195
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0032 0.011 0.0103
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0039 0.1055
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0031 0.0068
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0031 0.0068
Leishmania major farnesyltransferase beta subunit 0.0058 0.0275 0.7381
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.011 0.0229
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0032 0.011 0.0229
Echinococcus granulosus dna polymerase eta 0.0019 0.003 0.005
Schistosoma mansoni bhlhzip transcription factor bigmax 0.0466 0.2883 0.6417
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0041
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0412 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.011 0.0229
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0039 0.1055
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0017 0.0019 0.0024
Schistosoma mansoni neuropeptide receptor 0.0032 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.0016 0.0008 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0068
Onchocerca volvulus 0.0032 0.011 0.0205
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.001 0.0023
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0212 0.126 0.2806
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0016
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0021 0.0045 0.0083
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0465 0.2876 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.011 0.0246
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0032 0.011 0.0205
Echinococcus multilocularis calpain A 0.0057 0.0271 0.0264
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.015 0.0317
Mycobacterium leprae Probable lipase LipE 0.0073 0.0373 0.8825
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.011 0.0103
Schistosoma mansoni biogenic amine receptor 0.0032 0.011 0.0229
Schistosoma mansoni hypothetical protein 0.0036 0.0138 0.0291
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0031 0.0068
Trypanosoma cruzi protein farnesyltransferase, putative 0.0058 0.0275 0.7381
Loa Loa (eye worm) steroid hormone receptor 0.0017 0.0019 0.0041
Brugia malayi sulfakinin receptor protein 0.0032 0.011 0.0246
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0195
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0042 0.0176 0.416

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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