Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | phenylalanyl tRNA synthetase alpha chain B | 0.04 | 0.2119 | 0.2843 |
Echinococcus multilocularis | GPCR, family 2 | 0.0019 | 0.0011 | 0.0015 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0018 | 0.0003 | 0.0005 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0018 | 0.0003 | 0.0005 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0048 | 0.0169 | 0.0227 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0071 | 0.0299 | 0.0401 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase subunit alpha | 0.0131 | 0.0634 | 0.0851 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0052 | 0.0197 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0011 | 0.0002 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0047 | 0.0164 | 0.0727 |
Onchocerca volvulus | 0.0114 | 0.0536 | 1 | |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0237 | 0.1219 | 0.5746 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0406 | 0.0545 |
Echinococcus granulosus | phenylalanyl tRNA synthetase | 0.0182 | 0.0914 | 0.1226 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0108 | 0.0506 | 0.2347 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0071 | 0.0299 | 0.0291 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0047 | 0.0164 | 0.0727 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0011 | 0.0014 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0048 | 0.0169 | 0.0227 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0019 | 0.0011 | 0.0015 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0108 | 0.0506 | 0.2347 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0169 | 0.0227 |
Loa Loa (eye worm) | phenylalanyl-tRNA synthetase | 0.0182 | 0.0914 | 0.4302 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.002 | 0.0026 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0019 | 0.0011 | 0.0015 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0108 | 0.0506 | 0.0497 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0011 | 0.0038 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0461 | 0.2457 | 0.3297 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0244 | 0.0328 |
Leishmania major | phenylalanyl-tRNA synthetase alpha chain, putative | 0.04 | 0.2119 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0019 | 0.0011 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.1515 | 0.7145 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0123 | 0.0588 | 0.2765 |
Schistosoma mansoni | phosphoglucomutase | 0.0043 | 0.0144 | 0.0193 |
Echinococcus multilocularis | phenylalanyl tRNA synthetase alpha chain B | 0.04 | 0.2119 | 0.2843 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.0406 | 0.1876 |
Onchocerca volvulus | 0.0048 | 0.0169 | 0.2264 | |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0244 | 0.0328 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0197 | 0.0996 | 0.1336 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0299 | 0.1398 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.0299 | 0.0291 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0071 | 0.0299 | 0.0291 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0019 | 0.0011 | 0.0004 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0206 | 0.0276 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0048 | 0.0169 | 0.0227 |
Trypanosoma brucei | glucosidase, putative | 0.0044 | 0.0148 | 0.065 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0071 | 0.0302 | 0.0405 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0044 | 0.0148 | 0.0198 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0029 | 0.0068 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0011 | 0.0034 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.002 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0299 | 0.1398 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0011 | 0.0014 |
Trypanosoma brucei | unspecified product | 0.0047 | 0.0164 | 0.0727 |
Giardia lamblia | Ribonuclease H | 0.0043 | 0.0144 | 0.0632 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0108 | 0.0506 | 0.2347 |
Onchocerca volvulus | Ribonuclease H1 homolog | 0.0043 | 0.0144 | 0.1732 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0043 | 0.0144 | 0.0632 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0044 | 0.0148 | 0.0682 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0108 | 0.0506 | 0.2347 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0291 | 0.1515 | 0.2033 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0108 | 0.0506 | 0.2347 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0039 | 0.0053 |
Echinococcus multilocularis | muscleblind protein | 0.0291 | 0.1515 | 0.2033 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0134 | 0.018 |
Giardia lamblia | Phenylalanyl-tRNA synthetase alpha chain | 0.04 | 0.2119 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0108 | 0.0506 | 0.2347 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0019 | 0.0011 | 0.0038 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0108 | 0.0506 | 0.2347 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.04 | 0.2119 | 1 |
Plasmodium falciparum | phenylalanine--tRNA ligase alpha subunit | 0.04 | 0.2119 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0011 | 0.0014 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0406 | 0.0545 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0169 | 0.0751 |
Plasmodium vivax | phenylalanine--tRNA ligase, putative | 0.0182 | 0.0914 | 0.4123 |
Brugia malayi | RNA binding protein | 0.0123 | 0.0588 | 0.274 |
Toxoplasma gondii | phenylalanyl-tRNA synthetase alpha chain A, putative | 0.04 | 0.2119 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0302 | 0.138 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0044 | 0.0148 | 0.065 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.0299 | 0.0291 |
Loa Loa (eye worm) | beta-lactamase | 0.0071 | 0.0299 | 0.1398 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0011 | 0.0015 |
Schistosoma mansoni | phosphoglucomutase | 0.0043 | 0.0144 | 0.0193 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0043 | 0.0144 | 0.0632 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0011 | 0.0014 |
Wolbachia endosymbiont of Brugia malayi | ribonuclease HI | 0.0043 | 0.0144 | 0.0135 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.0299 | 0.1369 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0406 | 0.0545 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0044 | 0.0148 | 0.065 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0131 | 0.0634 | 0.2956 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0299 | 0.1398 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0081 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0299 | 0.1398 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0039 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0134 | 0.0617 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0206 | 0.0955 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0011 | 0.0034 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0108 | 0.0506 | 0.2374 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0108 | 0.0506 | 0.189 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0071 | 0.0302 | 0.0405 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1363 | 0.7453 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0104 | 0.014 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0108 | 0.0506 | 0.2347 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0406 | 0.0545 |
Echinococcus multilocularis | tar DNA binding protein | 0.0123 | 0.0588 | 0.0789 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0299 | 0.1398 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.0214 | 0.0712 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0461 | 0.2457 | 0.3297 |
Onchocerca volvulus | 0.0071 | 0.0299 | 0.5007 | |
Trypanosoma brucei | ribonuclease H1 | 0.0043 | 0.0144 | 0.0632 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.0299 | 0.1369 |
Brugia malayi | 6-phosphofructokinase | 0.0108 | 0.0506 | 0.2347 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0011 | 0.0015 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0044 | 0.0148 | 0.0198 |
Entamoeba histolytica | phenylalanyl-tRNA synthetase alpha subunit, putative | 0.04 | 0.2119 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0071 | 0.0299 | 0.1369 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.0588 | 0.0789 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0019 | 0.0011 | 0.0015 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase mitochondrial | 0.0182 | 0.0914 | 0.1226 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0011 | 0.0015 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0068 | 0.0272 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.006 | 0.0239 | 0.1085 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.0043 | 0.0144 | 0.0632 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0131 | 0.0634 | 0.2956 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0461 | 0.2457 | 0.3297 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0302 | 0.0405 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0299 | 0.1398 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0406 | 0.0545 |
Echinococcus granulosus | geminin | 0.0164 | 0.0813 | 0.109 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.0588 | 0.0789 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0454 | 0.2419 | 0.2412 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.0329 | 0.1508 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0011 | 0.0002 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.0264 | 0.0354 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0071 | 0.0299 | 0.1369 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0071 | 0.0299 | 0.1398 |
Toxoplasma gondii | Ferredoxin-fold anticodon binding domain-containing protein | 0.0182 | 0.0914 | 0.4123 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0206 | 0.0276 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0048 | 0.0169 | 0.0227 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0.0148 | 0.065 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.0588 | 0.0789 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0118 | 0.054 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0039 | 0.0053 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0011 | 0.0014 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0044 | 0.0148 | 0.065 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0019 | 0.0011 | 0.0004 |
Brugia malayi | TAR-binding protein | 0.0123 | 0.0588 | 0.274 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1363 | 0.7453 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0302 | 0.138 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0123 | 0.0588 | 0.274 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0108 | 0.0506 | 0.0497 |
Treponema pallidum | ribonuclease H (rnhA) | 0.0043 | 0.0144 | 0.037 |
Loa Loa (eye worm) | hypothetical protein | 0.04 | 0.2119 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0044 | 0.0148 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0131 | 0.0602 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0062 | 0.0083 |
Plasmodium falciparum | phenylalanine--tRNA ligase | 0.015 | 0.0737 | 0.326 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.0588 | 0.0789 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0206 | 0.0276 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0237 | 0.1219 | 0.5746 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0108 | 0.0506 | 0.0678 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0068 | 0.0272 |
Loa Loa (eye worm) | TAR-binding protein | 0.0123 | 0.0588 | 0.2765 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.1515 | 0.7145 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0068 | 0.0272 |
Schistosoma mansoni | phosphoglucomutase | 0.0043 | 0.0144 | 0.0193 |
Echinococcus granulosus | ribonuclease H1 | 0.0043 | 0.0144 | 0.0193 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.0588 | 0.0789 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0041 | 0.0134 | 0.0584 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0044 | 0.0148 | 0.065 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0197 | 0.0996 | 0.4689 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0071 | 0.0299 | 0.1369 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0011 | 0.0014 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0047 | 0.0164 | 0.0727 |
Brugia malayi | phenylalanyl (f) trna synthetase protein 1 | 0.04 | 0.2119 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0123 | 0.0588 | 0.2765 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.0406 | 0.1904 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.0299 | 0.0291 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0071 | 0.0299 | 0.0401 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0071 | 0.0299 | 0.0291 |
Schistosoma mansoni | alpha-glucosidase | 0.0169 | 0.0844 | 0.1132 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.006 | 0.0239 | 0.1085 |
Schistosoma mansoni | hypothetical protein | 0.0289 | 0.1506 | 0.202 |
Brugia malayi | beta-lactamase family protein | 0.0071 | 0.0299 | 0.1369 |
Schistosoma mansoni | alpha glucosidase | 0.0044 | 0.0148 | 0.0198 |
Echinococcus granulosus | tar DNA binding protein | 0.0123 | 0.0588 | 0.0789 |
Mycobacterium ulcerans | beta-lactamase | 0.0071 | 0.0299 | 0.0291 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0117 | 0.0505 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0108 | 0.0506 | 0.2347 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0029 | 0.0068 | 0.0272 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0071 | 0.0299 | 0.0291 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0071 | 0.0299 | 0.0401 |
Plasmodium falciparum | phenylalanine--tRNA ligase | 0.0182 | 0.0914 | 0.4123 |
Brugia malayi | beta-lactamase | 0.0071 | 0.0299 | 0.1369 |
Mycobacterium tuberculosis | Probable phenylalanyl-tRNA synthetase, alpha chain PheS | 0.1822 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0296 | 0.1383 |
Echinococcus granulosus | neuropeptide s receptor | 0.0461 | 0.2457 | 0.3297 |
Brugia malayi | phenylalanyl-tRNA synthetase, mitochondrial precursor, putative | 0.0182 | 0.0914 | 0.4283 |
Brugia malayi | RNase H family protein | 0.0043 | 0.0144 | 0.0632 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0071 | 0.0302 | 0.0405 |
Brugia malayi | phosphofructokinase | 0.0108 | 0.0506 | 0.2347 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0108 | 0.0506 | 0.0678 |
Leishmania major | hypothetical protein, conserved | 0.0071 | 0.0299 | 0.1369 |
Brugia malayi | beta-lactamase family protein | 0.0071 | 0.0299 | 0.1369 |
Brugia malayi | 6-phosphofructokinase | 0.0108 | 0.0506 | 0.2347 |
Plasmodium vivax | phenylalanine--tRNA ligase, putative | 0.0131 | 0.0634 | 0.276 |
Loa Loa (eye worm) | phosphofructokinase | 0.0108 | 0.0506 | 0.2374 |
Brugia malayi | Muscleblind-like protein | 0.0291 | 0.1515 | 0.7136 |
Trypanosoma cruzi | phenylalanyl-tRNA synthetase alpha chain, putative | 0.04 | 0.2119 | 1 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0048 | 0.0169 | 0.2264 |
Trypanosoma brucei | RNA helicase, putative | 0.0161 | 0.0798 | 0.3734 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0071 | 0.0299 | 0.1369 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0048 | 0.0169 | 0.0783 |
Toxoplasma gondii | ribonuclease HI protein | 0.0043 | 0.0144 | 0.037 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0044 | 0.0148 | 0.065 |
Echinococcus granulosus | muscleblind protein | 0.0291 | 0.1515 | 0.2033 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0071 | 0.0299 | 0.0401 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0197 | 0.0996 | 0.1336 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0.0148 | 0.065 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.0299 | 0.1369 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.006 | 0.0239 | 0.1115 |
Wolbachia endosymbiont of Brugia malayi | phenylalanyl-tRNA synthetase subunit alpha | 0.1822 | 1 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0237 | 0.1219 | 0.5732 |
Trichomonas vaginalis | esterase, putative | 0.0071 | 0.0299 | 0.1369 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0023 | 0.0031 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0029 | 0.0068 | 0.0272 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0044 | 0.0148 | 0.065 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0197 | 0.0996 | 0.4671 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0068 | 0.0272 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0206 | 0.0276 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0047 | 0.0164 | 0.0727 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0.0148 | 0.065 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0044 | 0.0148 | 0.065 |
Echinococcus multilocularis | geminin | 0.0164 | 0.0813 | 0.109 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0197 | 0.0996 | 0.1336 |
Brugia malayi | hypothetical protein | 0.0071 | 0.0302 | 0.138 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0068 | 0.0272 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0108 | 0.0506 | 0.2134 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0044 | 0.0148 | 0.065 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0048 | 0.0169 | 0.0227 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0.0148 | 0.065 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.0813 | 0.109 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0071 | 0.0299 | 0.0291 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0071 | 0.0299 | 0.1369 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0104 | 0.014 |
Schistosoma mansoni | alpha-glucosidase | 0.0169 | 0.0844 | 0.1132 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0406 | 0.0545 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.0068 | 0.0059 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0071 | 0.0299 | 0.0291 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0.0148 | 0.065 |
Toxoplasma gondii | ABC1 family protein | 0.0071 | 0.0299 | 0.1128 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0011 | 0.0015 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 0.0798 | 0.1071 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0081 | 0.0109 |
Mycobacterium ulcerans | lipase LipD | 0.0071 | 0.0299 | 0.0291 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0302 | 0.138 |
Onchocerca volvulus | 0.0071 | 0.0299 | 0.5007 | |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0302 | 0.138 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0011 | 0.0002 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0062 | 0.0275 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0044 | 0.0148 | 0.065 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.0813 | 0.109 |
Mycobacterium ulcerans | phenylalanyl-tRNA synthetase subunit alpha | 0.1822 | 1 | 1 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0071 | 0.0299 | 0.0291 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0011 | 0.0014 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0108 | 0.0506 | 0.2374 |
Plasmodium vivax | hypothetical protein, conserved | 0.0071 | 0.0299 | 0.1128 |
Treponema pallidum | phenylalanyl-tRNA synthetase subunit alpha | 0.04 | 0.2119 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0011 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0169 | 0.0783 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0169 | 0.0227 |
Echinococcus multilocularis | phenylalanyl tRNA synthetase | 0.0182 | 0.0914 | 0.1226 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0187 | 0.0943 | 0.1265 |
Echinococcus granulosus | microtubule associated protein 2 | 0.1363 | 0.7453 | 1 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0108 | 0.0506 | 0.2347 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0406 | 0.0545 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0071 | 0.0299 | 0.0291 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0108 | 0.0506 | 0.0678 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0071 | 0.0299 | 0.1369 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0081 | 0.0109 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0068 | 0.0272 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0011 | 0.0002 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0023 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0239 | 0.1115 |
Echinococcus multilocularis | ribonuclease H1 | 0.0043 | 0.0144 | 0.0193 |
Leishmania major | ribonuclease H1, putative | 0.0043 | 0.0144 | 0.0632 |
Plasmodium vivax | phenylalanine--tRNA ligase alpha subunit, putative | 0.04 | 0.2119 | 1 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0169 | 0.0751 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0236 | 0.0317 |
Onchocerca volvulus | 0.0071 | 0.0299 | 0.5007 | |
Brugia malayi | RNase H family protein | 0.0043 | 0.0144 | 0.0632 |
Echinococcus granulosus | GPCR family 2 | 0.0019 | 0.0011 | 0.0015 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0062 | 0.0242 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0071 | 0.0299 | 0.0291 |
Trypanosoma brucei | phenylalanyl-tRNA synthetase alpha chain, putative | 0.04 | 0.2119 | 1 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0108 | 0.0506 | 0.0678 |
Brugia malayi | RNase H family protein | 0.0043 | 0.0144 | 0.0632 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.0068 | 0.0059 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0003 | 0.0005 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase subunit alpha | 0.04 | 0.2119 | 0.2843 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0023 | 0.0031 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0206 | 0.0955 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.015 | 0.0693 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0081 | 0.0109 |
Mycobacterium leprae | Probable phenylalanyl-tRNA synthetase, alpha chain PheS | 0.0268 | 0.1391 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0187 | 0.0943 | 0.1265 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0011 | 0.0014 |
Mycobacterium ulcerans | hypothetical protein | 0.0071 | 0.0299 | 0.0291 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0044 | 0.0148 | 0.065 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0003 | 0.0005 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0206 | 0.0276 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0206 | 0.0924 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 100 uM | Inhibition of HIV1 YU2 gp120 binding to CD4 expressing Cf2Th-CD4/CCR5 cells assessed as inhibition of viral infection after 48 hrs | ChEMBL. | 21169023 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.