Detailed information for compound 1486046

Basic information

Technical information
  • TDR Targets ID: 1486046
  • Name: N-cyclopropyl-3-[(2,4-dimethylphenyl)sulfamoy l]benzamide
  • MW: 344.428 | Formula: C18H20N2O3S
  • H donors: 2 H acceptors: 3 LogP: 3.01 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(c(c1)C)NS(=O)(=O)c1cccc(c1)C(=O)NC1CC1
  • InChi: 1S/C18H20N2O3S/c1-12-6-9-17(13(2)10-12)20-24(22,23)16-5-3-4-14(11-16)18(21)19-15-7-8-15/h3-6,9-11,15,20H,7-8H2,1-2H3,(H,19,21)
  • InChiKey: LGUYYLNCDRCHIS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • T0508-3074
  • ZINC03230949
  • Enamine_002717

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Immunoglobulin 0.0125 0.0625 0.0763
Entamoeba histolytica protein kinase, putative 0.0063 0.0076 0.0192
Brugia malayi Protein kinase domain containing protein 0.0105 0.0452 0.0643
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Loa Loa (eye worm) TK/ALK protein kinase 0.0537 0.4277 0.6175
Loa Loa (eye worm) protein kinase domain-containing protein 0.0058 0.003 0.0032
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0247 0.1702 0.4325
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.1513 0.1862
Loa Loa (eye worm) hypothetical protein 0.0422 0.3257 0.4699
Loa Loa (eye worm) hypothetical protein 0.0057 0.0027 0.0028
Trichomonas vaginalis cyclin A, putative 0.0065 0.0095 0.0189
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Loa Loa (eye worm) TK protein kinase 0.0281 0.2003 0.2886
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0342 0.2551 0.3679
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus multilocularis mitogen activated protein kinase 0.0121 0.0593 0.0724
Toxoplasma gondii CMGC kinase, CK2 family 0.0155 0.0887 0.2195
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Schistosoma mansoni tyrosine kinase 0.0458 0.3575 0.4412
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0185 0.1156 0.115
Trichomonas vaginalis heat shock protein, putative 0.0199 0.1279 0.3214
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.1156 0.29
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0386 0.2941 1
Brugia malayi kinase, mitochondrial precursor 0.0341 0.2543 0.3666
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0259 0.181 0.2229
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0115 0.0541 0.1308
Brugia malayi SRC-1 0.0131 0.0676 0.0967
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0112 0.0513 0.1257
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0121 0.0593 0.1442
Loa Loa (eye worm) hypothetical protein 0.0058 0.003 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.1702 0.2096
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0057 0.0021 0.0017
Entamoeba histolytica ankyrin repeat protein 0.0058 0.003 0.0076
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0105 0.0452 0.1081
Entamoeba histolytica protein kinase domain containing protein 0.0076 0.0193 0.049
Echinococcus multilocularis MAM 0.0057 0.0027 0.0024
Schistosoma mansoni hypothetical protein 0.0083 0.025 0.03
Entamoeba histolytica serine/threonine protein kinase, putative 0.021 0.1382 0.351
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0112 0.0513 0.1238
Giardia lamblia Casein kinase II beta chain 0.0075 0.018 0.0384
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.021 0.1382 0.3461
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0058 0.003 0.0027
Entamoeba histolytica hypothetical protein 0.0058 0.0032 0.0081
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0102 0.0424 0.0417
Echinococcus granulosus cyclin dependent kinase 5 0.0105 0.0452 0.0445
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0058 0.003 0.0032
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.021 0.1382 0.1987
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0057 0.0022 0.0017
Brugia malayi Protein kinase c protein 2 0.0114 0.0525 0.0749
Brugia malayi Furin-like cysteine rich region family protein 0.0599 0.4822 0.6962
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Entamoeba histolytica hypothetical protein 0.0058 0.003 0.0076
Loa Loa (eye worm) hypothetical protein 0.0187 0.1178 0.1692
Loa Loa (eye worm) TK protein kinase 0.0058 0.003 0.0032
Trichomonas vaginalis TKL family protein kinase 0.006 0.0051 0.0075
Schistosoma mansoni nck2/grb4 0.0073 0.0165 0.0194
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0125 0.0625 0.0763
Echinococcus multilocularis RNA directed DNA polymerase 0.008 0.0231 0.0276
Brugia malayi heat shock protein 90 0.0499 0.3936 0.5681
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Onchocerca volvulus 0.0058 0.003 0.0005
Onchocerca volvulus 0.0102 0.0424 0.0684
Brugia malayi Csnk2b protein 0.0075 0.018 0.0249
Schistosoma mansoni tyrosine kinase 0.0131 0.0676 0.0827
Onchocerca volvulus 0.0058 0.003 0.0005
Echinococcus multilocularis cyclin B 0.0065 0.0095 0.0108
Entamoeba histolytica protein kinase, putative 0.0115 0.0541 0.1374
Entamoeba histolytica serine/threonine kinase, putative 0.0058 0.003 0.0076
Loa Loa (eye worm) PEK/PEK protein kinase 0.0402 0.3081 0.4444
Giardia lamblia Kinase, CMGC MAPK 0.0121 0.0593 0.1442
Schistosoma mansoni adapter molecule crk 0.0073 0.0165 0.0194
Loa Loa (eye worm) CDC7 protein kinase 0.0134 0.0701 0.1003
Echinococcus multilocularis serine threonine protein kinase 0.014 0.0756 0.0925
Onchocerca volvulus 0.0102 0.0424 0.0684
Trichomonas vaginalis CMGC family protein kinase 0.0155 0.0887 0.2213
Brugia malayi ephrin receptor 1 precursor 0.0058 0.003 0.0032
Entamoeba histolytica casein kinase, putative 0.0155 0.0887 0.2255
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus multilocularis heat shock protein 90 0.0386 0.2941 0.3628
Trichomonas vaginalis protein kinase atn1, putative 0.0058 0.003 0.0022
Toxoplasma gondii DNA topoisomerase 2, putative 0.0112 0.0513 0.1238
Echinococcus granulosus eukaryotic elongation factor 2 kinase 0.0065 0.0091 0.0083
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0058 0.003 0.0032
Schistosoma mansoni nephrin 0.0147 0.0818 0.1002
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0386 0.2941 0.2936
Plasmodium falciparum heat shock protein 90 0.0499 0.3936 1
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0145 0.0803 0.0796
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0058 0.003 0.0027
Echinococcus granulosus protein kinase C gamma type 0.014 0.0756 0.0749
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0101 0.0413 0.0502
Trypanosoma cruzi casein kinase II, putative 0.0155 0.0887 0.2195
Echinococcus granulosus tyrosine protein kinase Lyn 0.0149 0.0839 0.0832
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0121 0.0593 0.1442
Plasmodium falciparum casein kinase II beta chain 0.0075 0.018 0.0384
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1382 0.3475
Echinococcus granulosus serine threonine protein kinase 0.0225 0.1513 0.1507
Echinococcus granulosus tyrosine protein kinase Fyn 0.0131 0.0676 0.0669
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0061 0.0059 0.0063
Entamoeba histolytica serine/threonine kinase, putative 0.0058 0.003 0.0076
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0076 0.0193 0.0417
Loa Loa (eye worm) SRC-1 0.0131 0.0676 0.0967
Trichomonas vaginalis AGC family protein kinase 0.0103 0.0428 0.104
Trypanosoma brucei heat shock protein, putative 0.0499 0.3936 1
Echinococcus granulosus serine:threonine protein kinase haspin 0.0139 0.0752 0.0745
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0112 0.0513 0.1238
Brugia malayi Fibronectin type III domain containing protein 0.0125 0.0625 0.0892
Trypanosoma cruzi DNA topoisomerase II, putative 0.0112 0.0513 0.1238
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Echinococcus multilocularis endoplasmin 0.0386 0.2941 0.3628
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0076 0.0193 0.0229
Loa Loa (eye worm) hypothetical protein 0.0065 0.0095 0.0126
Entamoeba histolytica protein kinase, putative 0.0247 0.1702 0.4325
Echinococcus granulosus serine threonine protein kinase nrc 0.006 0.0051 0.0044
Echinococcus multilocularis dual specificity serine:threonine tyrosine 0.0165 0.0976 0.1197
Brugia malayi Casein kinase II, alpha chain 0.0155 0.0887 0.1272
Loa Loa (eye worm) hypothetical protein 0.0058 0.003 0.0032
Echinococcus granulosus retinal guanylyl cyclase 2 0.0058 0.003 0.0022
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0121 0.0593 0.1442
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Trypanosoma brucei DNA topoisomerase ii 0.0112 0.0513 0.1238
Echinococcus granulosus roundabout 2 0.0167 0.0996 0.0989
Brugia malayi Protein kinase domain containing protein 0.0359 0.2695 0.3886
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0058 0.003 0.0022
Giardia lamblia Kinase, CDC7 0.0134 0.0701 0.172
Schistosoma mansoni protein kinase 0.0058 0.003 0.0027
Loa Loa (eye worm) TK protein kinase 0.0058 0.003 0.0032
Loa Loa (eye worm) TK/ROR protein kinase 0.008 0.0223 0.0311
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0593 0.1461
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0112 0.0513 0.0837
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0057 0.0021 0.002
Loa Loa (eye worm) haspin protein kinase 0.0139 0.0752 0.1076
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0058 0.003 0.0032
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Schistosoma mansoni vav2 0.0061 0.0059 0.0063
Schistosoma mansoni tyrosine kinase 0.0458 0.3575 0.4412
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trichomonas vaginalis STE family protein kinase 0.0058 0.003 0.0022
Schistosoma mansoni tyrosine kinase 0.01 0.0401 0.0486
Echinococcus granulosus serine:threonine protein kinase haspin 0.0139 0.0752 0.0745
Loa Loa (eye worm) hypothetical protein 0.0057 0.0027 0.0028
Brugia malayi Protein kinase domain containing protein 0.0268 0.1888 0.272
Loa Loa (eye worm) hypothetical protein 0.0065 0.0091 0.0121
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.0424 0.0602
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Trypanosoma brucei Heat shock protein 83, putative 0.0499 0.3936 1
Trypanosoma brucei heat shock protein, putative 0.0499 0.3936 1
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Schistosoma mansoni serine/threonine kinase 0.0292 0.2101 0.2589
Onchocerca volvulus 0.0102 0.0424 0.0684
Loa Loa (eye worm) STE/STE20/YSK protein kinase 0.0225 0.1513 0.2177
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0683 0.5567 0.6876
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0541 0.1327
Echinococcus granulosus protein kinase c epsilon type 0.0072 0.0153 0.0145
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Echinococcus multilocularis hypothetical protein 0.0083 0.025 0.03
Giardia lamblia Grp94/Hsp90 0.0386 0.2941 0.7453
Echinococcus multilocularis rac serine:threonine kinase 0.0064 0.0089 0.01
Brugia malayi bone morphogenetic protein type 1 receptor 0.0058 0.003 0.0032
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0386 0.2941 1
Entamoeba histolytica protein kinase , putative 0.0247 0.1702 0.4325
Echinococcus multilocularis cyclin dependent kinase 1 0.0105 0.0452 0.055
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.006 0.0052 0.0065
Echinococcus granulosus epidermal growth factor receptor 0.0458 0.3575 0.357
Echinococcus multilocularis transfer RNA-Thr 0.0394 0.3012 0.3715
Onchocerca volvulus Serine\/threonine kinase homolog 0.021 0.1382 0.2334
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.0424 0.0602
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0701 0.0858
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0073 0.0165 0.0194
Loa Loa (eye worm) TK/Met protein kinase 0.0058 0.003 0.0032
Echinococcus multilocularis protein kinase c epsilon type 0.0072 0.0153 0.018
Trypanosoma brucei protein kinase, putative 0.0145 0.0806 0.1988
Loa Loa (eye worm) TK/EGFR protein kinase 0.0599 0.4822 0.6962
Echinococcus multilocularis N chimaerin 0.0057 0.0022 0.0017
Echinococcus multilocularis tyrosine protein kinase csk 0.0058 0.003 0.0027
Schistosoma mansoni tyrosine kinase 0.04 0.3064 0.378
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Brugia malayi cell division control protein 2 homolog 0.0105 0.0452 0.0643
Brugia malayi intracellular kinase 0.0115 0.0541 0.0771
Loa Loa (eye worm) hypothetical protein 0.0167 0.0996 0.1429
Schistosoma mansoni protein kinase 0.0058 0.003 0.0027
Schistosoma mansoni tyrosine kinase 0.0259 0.181 0.2229
Trichomonas vaginalis CMGC family protein kinase 0.0155 0.0887 0.2213
Brugia malayi Protein kinase domain containing protein 0.0057 0.0021 0.002
Echinococcus granulosus heat shock protein 90 0.0386 0.2941 0.2936
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Plasmodium vivax casein kinase II beta chain, putative 0.0075 0.018 0.0384
Trichomonas vaginalis CAMK family protein kinase 0.0165 0.0976 0.2439
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0057 0.0022 0.002
Treponema pallidum heat shock protein 90 0.0386 0.2941 1
Plasmodium falciparum DNA topoisomerase 2 0.0112 0.0513 0.1238
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Plasmodium vivax endoplasmin, putative 0.0499 0.3936 1
Echinococcus granulosus tyrosine protein kinase shark 0.0968 0.8093 0.8092
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Trichomonas vaginalis receptor histidine kinase, putative 0.0112 0.0513 0.1257
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0152 0.0865 0.106
Echinococcus granulosus serine:threonine protein kinase haspin 0.0139 0.0752 0.0745
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0058 0.003 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trypanosoma cruzi DNA topoisomerase II, putative 0.0112 0.0513 0.1238
Loa Loa (eye worm) hypothetical protein 0.0065 0.0095 0.0126
Echinococcus multilocularis tyrosine protein kinase 0.0058 0.003 0.0027
Loa Loa (eye worm) AUR protein kinase 0.0247 0.1702 0.2451
Mycobacterium ulcerans heat shock protein 90 0.0386 0.2941 1
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0523 0.4149 0.5122
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0274 0.1947 0.4909
Onchocerca volvulus 0.0058 0.003 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1382 0.3475
Echinococcus multilocularis serine:threonine protein kinase N2 0.0057 0.0021 0.0017
Brugia malayi Protein kinase domain containing protein 0.0394 0.3012 0.4344
Entamoeba histolytica hypothetical protein 0.0058 0.0032 0.0081
Schistosoma mansoni tyrosine kinase 0.0131 0.0676 0.0827
Plasmodium falciparum glycogen synthase kinase 3 0.0115 0.0541 0.1308
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0057 0.0027 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0268 0.1888 0.4769
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0065 0.0095 0.0167
Trichomonas vaginalis DNA topoisomerase II, putative 0.0112 0.0513 0.1257
Loa Loa (eye worm) TK/FER protein kinase 0.0058 0.003 0.0032
Brugia malayi hypothetical protein 0.0057 0.0027 0.0028
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0131 0.0676 0.0827
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0102 0.0424 0.0515
Schistosoma mansoni heat shock protein 0.0499 0.3936 0.4858
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.008 0.0223 0.0266
Trypanosoma cruzi CYC2-like cyclin, putative 0.0065 0.0095 0.0167
Toxoplasma gondii Hsp90 domain-containing protein 0.0199 0.1279 0.3199
Schistosoma mansoni tyrosine kinase 0.0131 0.0676 0.0827
Entamoeba histolytica cell division protein kinase 2, putative 0.0129 0.0665 0.169
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0342 0.2551 0.3146
Onchocerca volvulus 0.0134 0.0701 0.1162
Brugia malayi Variant SH3 domain containing protein 0.0057 0.0022 0.002
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0058 0.003 0.0022
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Giardia lamblia Kinase, CMGC GSK 0.0115 0.0541 0.1308
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0112 0.0513 0.1257
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0259 0.181 0.2229
Plasmodium falciparum protein kinase, putative 0.0076 0.0193 0.0417
Schistosoma mansoni pyruvate dehydrogenase 0.0229 0.1548 0.1905
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0259 0.181 0.1804
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Giardia lamblia Kinase, CMGC CK2 0.0155 0.0887 0.2195
Echinococcus granulosus retinal guanylyl cyclase 2 0.0058 0.003 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus granulosus tyrosine protein kinase pr2 0.0058 0.003 0.0022
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Echinococcus multilocularis cyclin dependent kinase 1 0.0105 0.0452 0.055
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0155 0.0887 0.1272
Echinococcus granulosus twitchin 0.0165 0.0981 0.0974
Loa Loa (eye worm) hypothetical protein 0.0341 0.2543 0.3666
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0386 0.2941 0.7453
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.003 0.0027
Echinococcus granulosus Immunoglobulin 0.0125 0.0625 0.0617
Trichomonas vaginalis AGC family protein kinase 0.0103 0.0428 0.104
Onchocerca volvulus 0.0058 0.003 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Brugia malayi Protein kinase domain containing protein 0.0577 0.4629 0.6683
Echinococcus multilocularis NCK adaptor protein 0.0076 0.0193 0.0229
Schistosoma mansoni serine/threonine kinase 0.0057 0.0021 0.0017
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0085 0.027 0.0614
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Loa Loa (eye worm) AUR protein kinase 0.0247 0.1702 0.2451
Trypanosoma cruzi heat shock protein 85, putative 0.0499 0.3936 1
Giardia lamblia Heat shock protein HSP 90-alpha 0.0499 0.3936 1
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus granulosus retinal guanylyl cyclase 2 0.0058 0.003 0.0022
Schistosoma mansoni tyrosine kinase 0.0105 0.0453 0.055
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Trypanosoma cruzi cdc2-related kinase 1 0.0105 0.0452 0.1081
Leishmania major casein kinase II, putative 0.0155 0.0887 0.2195
Giardia lamblia Pms1-like protein 0.0112 0.0513 0.1238
Entamoeba histolytica cyclin, putative 0.0065 0.0095 0.0241
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0131 0.0676 0.0827
Onchocerca volvulus 0.0115 0.0541 0.0885
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0075 0.018 0.0384
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0115 0.0541 0.0659
Loa Loa (eye worm) hypothetical protein 0.0058 0.003 0.0032
Echinococcus multilocularis natriuretic peptide receptor 1 0.0058 0.003 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1382 0.3475
Brugia malayi Protein kinase domain containing protein 0.0102 0.0424 0.0602
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Echinococcus granulosus aurora kinase A 0.0247 0.1702 0.1696
Schistosoma mansoni cell adhesion molecule 0.0145 0.0803 0.0983
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus multilocularis mitogen activated protein kinase 14 0.0274 0.1947 0.2399
Echinococcus multilocularis FL cytokine receptor 0.0058 0.003 0.0027
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Loa Loa (eye worm) TK protein kinase 0.0058 0.003 0.0032
Loa Loa (eye worm) endoplasmin 0.0499 0.3936 0.5681
Plasmodium falciparum heat shock protein 90, putative 0.0199 0.1279 0.3199
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0131 0.0676 0.0669
Schistosoma mansoni protein kinase 0.0058 0.003 0.0027
Trypanosoma cruzi polo-like protein kinase, putative 0.021 0.1382 0.3461
Giardia lamblia Kinase, AGC PKA 0.006 0.0051 0.0055
Schistosoma mansoni hypothetical protein 0.0057 0.0027 0.0024
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Brugia malayi Protein kinase domain containing protein 0.0342 0.2551 0.3679
Trichomonas vaginalis STE family protein kinase 0.0225 0.1513 0.3811
Onchocerca volvulus 0.0065 0.0095 0.0117
Trypanosoma cruzi heat shock protein 85, putative 0.0499 0.3936 1
Plasmodium vivax hypothetical protein, conserved 0.0112 0.0513 0.1238
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0105 0.0452 0.0643
Loa Loa (eye worm) TK/ABL protein kinase 0.0523 0.4149 0.599
Entamoeba histolytica hypothetical protein 0.0058 0.003 0.0076
Loa Loa (eye worm) TK protein kinase 0.0102 0.0424 0.0602
Brugia malayi serine/threonine-protein kinase 6 0.0247 0.1702 0.2451
Schistosoma mansoni endoplasmin 0.0499 0.3936 0.4858
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0058 0.003 0.0027
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0058 0.003 0.0032
Entamoeba histolytica PH domain containing protein kinase, putative 0.0064 0.0089 0.0225
Trypanosoma cruzi myosin heavy chain kinase A, putative 0.0065 0.0091 0.0157
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.003 0.0022
Echinococcus multilocularis 0.0164 0.097 0.119
Leishmania major hypothetical protein, conserved 0.0112 0.0513 0.1238
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0085 0.027 0.0614
Entamoeba histolytica protein kinase 2, putative 0.006 0.0051 0.0131
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0075 0.018 0.0457
Echinococcus granulosus protein kinase c iota type 0.0069 0.013 0.0123
Loa Loa (eye worm) TK/FER protein kinase 0.0058 0.003 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0121 0.0593 0.1442
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0112 0.0513 0.0837
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Trichomonas vaginalis CMGC family protein kinase 0.0155 0.0887 0.2213
Echinococcus multilocularis c src tyrosine kinase 0.0131 0.0676 0.0827
Trichomonas vaginalis cyclins, putative 0.0065 0.0095 0.0189
Trypanosoma cruzi cdc2-related kinase 3 0.0105 0.0452 0.1081
Schistosoma mansoni serine/threonine protein kinase 0.0439 0.3404 0.42
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0121 0.0593 0.1442
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0105 0.0452 0.1081
Echinococcus granulosus mitogen activated protein kinase 11 0.0274 0.1947 0.1941
Loa Loa (eye worm) TK/DDR protein kinase 0.0058 0.003 0.0032
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Brugia malayi Protein kinase domain containing protein 0.0134 0.0701 0.1003
Schistosoma mansoni serine/threonine protein kinase 0.007 0.0139 0.0162
Trypanosoma cruzi Heat shock protein 83, putative 0.0499 0.3936 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.0424 0.0602
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0101 0.0413 0.0502
Plasmodium falciparum casein kinase II beta chain 0.0075 0.018 0.0384
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0105 0.0452 0.1081
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0057 0.0022 0.0017
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trypanosoma brucei heat shock protein 90, putative 0.0499 0.3936 1
Echinococcus granulosus integrin linked protein kinase 0.0058 0.003 0.0022
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0115 0.0541 0.1308
Schistosoma mansoni heat shock protein 0.0199 0.1279 0.1573
Echinococcus granulosus tyrosine protein kinase csk 0.0058 0.003 0.0022
Schistosoma mansoni ephrin receptor 0.0058 0.003 0.0027
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0112 0.0513 0.1238
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0058 0.003 0.0022
Trichomonas vaginalis CMGC family protein kinase 0.0155 0.0887 0.2213
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0385 0.2925 0.292
Schistosoma mansoni growth factor receptor-bound protein 0.0076 0.0193 0.0229
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Echinococcus multilocularis protein kinase 0.0058 0.003 0.0027
Trichomonas vaginalis heat shock protein, putative 0.0386 0.2941 0.7459
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1382 0.3475
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Trichomonas vaginalis TK family protein kinase 0.006 0.0051 0.0075
Echinococcus granulosus tyrosine protein kinase HCK 0.0058 0.003 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Entamoeba histolytica cysteine surface protein, putative 0.0058 0.003 0.0076
Brugia malayi RhoGAP domain containing protein 0.0057 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.0058 0.003 0.0032
Entamoeba histolytica PH domain containing protein kinase, putative 0.0064 0.0089 0.0225
Entamoeba histolytica receptor protein kinase, putative 0.0058 0.003 0.0076
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0121 0.0593 0.1442
Loa Loa (eye worm) RGC/RGC protein kinase 0.0058 0.003 0.0032
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0058 0.003 0.0032
Entamoeba histolytica tyrosin kinase, putative 0.0064 0.0087 0.0221
Schistosoma mansoni serine/threonine protein kinase 0.0359 0.2695 0.3324
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0341 0.2543 0.3135
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.006 0.0051 0.0055
Trypanosoma cruzi polo-like protein kinase, putative 0.021 0.1382 0.3461
Entamoeba histolytica hypothetical protein 0.0058 0.003 0.0076
Echinococcus granulosus casein kinase ii subunit alpha 0.0155 0.0887 0.088
Echinococcus multilocularis tyrosine protein kinase csk 0.0058 0.003 0.0027
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0075 0.018 0.0384
Echinococcus granulosus tyrosine protein kinase csk 0.0058 0.003 0.0022
Loa Loa (eye worm) TK/ACK protein kinase 0.0058 0.003 0.0032
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0112 0.0513 0.1238
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0058 0.003 0.0032
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0342 0.2551 0.4349
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.0424 0.0602
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0452 0.1101
Onchocerca volvulus Tyrosine kinase homolog 0.0713 0.5831 1
Trypanosoma brucei myosin heavy chain kinase A, putative 0.0065 0.0091 0.0157
Brugia malayi MAP kinase sur-1 0.0121 0.0593 0.0847
Echinococcus granulosus receptor type guanylyl cyclase 0.0058 0.003 0.0022
Trypanosoma brucei heat shock protein, putative 0.0499 0.3936 1
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0131 0.0676 0.0669
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0058 0.003 0.0076
Echinococcus multilocularis tyrosine protein kinase Srms 0.0102 0.0424 0.0515
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus multilocularis tyrosine protein kinase pr2 0.0058 0.003 0.0027
Schistosoma mansoni protein kinase 0.0058 0.003 0.0027
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0458 0.3575 0.357
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0197 0.1265 0.3161
Leishmania major myosin heavy chain kinase a-like protein 0.0065 0.0091 0.0157
Brugia malayi hypothetical protein 0.0058 0.003 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.1156 0.29
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0413 0.0502
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Loa Loa (eye worm) AUR protein kinase 0.0247 0.1702 0.2451
Loa Loa (eye worm) RGC/RGC protein kinase 0.0058 0.003 0.0032
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0359 0.2694 0.3323
Echinococcus multilocularis growth factor receptor bound protein 2 0.0073 0.0165 0.0194
Schistosoma mansoni tyrosine kinase 0.04 0.3064 0.378
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0865 0.106
Loa Loa (eye worm) hypothetical protein 0.0125 0.0625 0.0892
Loa Loa (eye worm) hypothetical protein 0.0125 0.0627 0.0895
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0112 0.0513 0.0731
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0101 0.0413 0.0406
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.0424 0.0602
Echinococcus granulosus protein kinase shaggy 0.0115 0.0541 0.0534
Onchocerca volvulus 0.0058 0.003 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.003 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0102 0.0424 0.0602
Trichomonas vaginalis AGC family protein kinase 0.0103 0.0428 0.104
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Loa Loa (eye worm) TK protein kinase 0.0058 0.003 0.0032
Trypanosoma brucei heat shock protein, putative 0.0499 0.3936 1
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Trypanosoma brucei heat shock protein 84, putative 0.0199 0.1279 0.3199
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0342 0.2551 0.3679
Brugia malayi Variant SH3 domain containing protein 0.0073 0.0165 0.0227
Entamoeba histolytica hypothetical protein 0.0058 0.003 0.0076
Trypanosoma cruzi heat shock protein 90, putative 0.03 0.2175 0.5491
Echinococcus multilocularis serine threonine protein kinase 0.0225 0.1513 0.1862
Loa Loa (eye worm) AGC/AKT protein kinase 0.0103 0.0428 0.0608
Trichomonas vaginalis cyclin B, putative 0.0065 0.0095 0.0189
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0058 0.003 0.0022
Loa Loa (eye worm) TK/EPH protein kinase 0.0058 0.003 0.0032
Echinococcus granulosus heat shock protein 0.0499 0.3936 0.3931
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0099 0.0391 0.0555
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trichomonas vaginalis cyclin B, putative 0.0065 0.0095 0.0189
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0199 0.1279 0.2158
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Schistosoma mansoni protein kinase 0.0076 0.0193 0.0229
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Schistosoma mansoni tyrosine kinase 0.0187 0.1178 0.1447
Entamoeba histolytica serine/threonine kinase, putative 0.0058 0.003 0.0076
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0064 0.0089 0.015
Plasmodium vivax heat shock protein, putative 0.0199 0.1279 0.3199
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Entamoeba histolytica ankyrin repeat protein 0.0058 0.003 0.0076
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0112 0.0513 0.1257
Trichomonas vaginalis CMGC family protein kinase 0.0155 0.0887 0.2213
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0187 0.1178 0.1171
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0247 0.1702 0.4294
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0058 0.003 0.0027
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0058 0.003 0.0027
Loa Loa (eye worm) TK/RYK protein kinase 0.0058 0.003 0.0032
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0075 0.018 0.0263
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Brugia malayi Protein kinase domain containing protein 0.0537 0.4279 0.6177
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0134 0.0701 0.1738
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0112 0.0513 0.0837
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0112 0.0513 0.1238
Schistosoma mansoni heat shock protein 0.0499 0.3936 0.4858
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0076 0.0193 0.0417
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0075 0.018 0.0457
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Leishmania major heat shock protein, putative 0.0199 0.1279 0.3199
Leishmania major protein kinase, putative 0.0076 0.0193 0.0417
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.003 0.0022
Trypanosoma brucei rac serine-threonine kinase, putative 0.0103 0.0428 0.102
Brugia malayi hypothetical protein 0.0102 0.0424 0.0602
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Echinococcus multilocularis tyrosine protein kinase Abl 0.0291 0.21 0.2588
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0563 0.0687
Echinococcus multilocularis epidermal growth factor receptor 0.0458 0.3575 0.4412
Brugia malayi Immunoglobulin I-set domain containing protein 0.0281 0.2003 0.2886
Trichomonas vaginalis CAMK family protein kinase 0.0058 0.003 0.0022
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0058 0.003 0.0027
Trichomonas vaginalis AGC family protein kinase 0.0103 0.0428 0.104
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.0424 0.0602
Loa Loa (eye worm) hypothetical protein 0.0394 0.3012 0.4344
Echinococcus multilocularis cyclin dependent kinase 5 0.0105 0.0452 0.055
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Echinococcus granulosus ephrin type A receptor 4 A 0.0058 0.003 0.0022
Echinococcus granulosus protein kinase 0.0058 0.003 0.0022
Trypanosoma brucei protein kinase, putative 0.0115 0.0541 0.1308
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0342 0.2551 0.3679
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Brugia malayi Raf kinase 0.0058 0.003 0.0032
Trichomonas vaginalis cyclin B, putative 0.0065 0.0095 0.0189
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0021 0.0017
Trypanosoma cruzi heat shock protein, putative 0.0199 0.1279 0.3199
Loa Loa (eye worm) TK/FER protein kinase 0.0058 0.003 0.0032
Brugia malayi hypothetical protein 0.0058 0.003 0.0032
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Brugia malayi Protein kinase domain containing protein 0.0402 0.3081 0.4444
Giardia lamblia Kinase, CMGC CDK 0.0105 0.0452 0.1081
Schistosoma mansoni hypothetical protein 0.0057 0.0027 0.0024
Echinococcus multilocularis ephrin type A receptor 4 A 0.0058 0.003 0.0027
Entamoeba histolytica tyrosin kinase, putative 0.0058 0.003 0.0076
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0115 0.0541 0.0534
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0274 0.1947 0.4909
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0413 0.0502
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0112 0.0513 0.1238
Brugia malayi Tyrosine-protein kinase abl-1 0.0291 0.21 0.3026
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.0424 0.0602
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0072 0.0153 0.021
Echinococcus granulosus tyrosine protein kinase csk 0.0058 0.003 0.0022
Brugia malayi Protein kinase domain containing protein 0.0683 0.5567 0.804
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0075 0.018 0.0384
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Loa Loa (eye worm) TTK protein kinase 0.0165 0.0976 0.14
Brugia malayi p70 ribosomal S6 kinase beta 0.0099 0.0391 0.0555
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0131 0.0676 0.0827
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0021 0.0017
Entamoeba histolytica hypothetical protein 0.0058 0.003 0.0076
Onchocerca volvulus 0.0134 0.0701 0.1162
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0112 0.0513 0.1238
Trypanosoma brucei cdc2-related kinase 3 0.0105 0.0452 0.1081
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0075 0.018 0.0384
Entamoeba histolytica hypothetical protein, conserved 0.0058 0.003 0.0076
Echinococcus granulosus tyrosine protein kinase Blk 0.0102 0.0424 0.0417
Loa Loa (eye worm) hypothetical protein 0.0058 0.003 0.0032
Loa Loa (eye worm) hypothetical protein 0.0337 0.25 0.3605
Trypanosoma cruzi aurora B kinase, putative 0.0247 0.1702 0.4282
Entamoeba histolytica hypothetical protein 0.0058 0.003 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0413 0.0502
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0115 0.0541 0.0771
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0058 0.003 0.0005
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0058 0.0032 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0165 0.0976 0.2439
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Brugia malayi serine/threonine kinase 12 0.0247 0.1702 0.2451
Brugia malayi serine/threonine protein kinase 6 0.0247 0.1702 0.2451
Echinococcus granulosus kinase suppressor of Ras 1 0.0058 0.003 0.0022
Schistosoma mansoni growth factor receptor-bound protein 0.0073 0.0165 0.0194
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0268 0.1888 0.272
Schistosoma mansoni protein kinase 0.0402 0.3081 0.3801
Echinococcus granulosus neuroglian 0.0147 0.0818 0.0811
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Schistosoma mansoni eukaryotic elongation factor 2 kinase (eef-2 kinase) 0.0065 0.0091 0.0103
Schistosoma mansoni protein kinase 0.0247 0.1702 0.2096
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Trichomonas vaginalis cyclin B, putative 0.0065 0.0095 0.0189
Trypanosoma brucei myosin heavy chain kinase A, putative 0.0065 0.0091 0.0157
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0452 0.1101
Echinococcus multilocularis tyrosine protein kinase Blk 0.0102 0.0424 0.0515
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0102 0.0424 0.0417
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0058 0.003 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0385 0.2925 0.4219
Brugia malayi Protein kinase domain containing protein 0.0102 0.0424 0.0602
Schistosoma mansoni pyruvate dehydrogenase 0.0341 0.2543 0.3135
Brugia malayi Receptor family ligand binding region containing protein 0.0058 0.003 0.0032
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0058 0.003 0.0032
Echinococcus granulosus natriuretic peptide receptor 1 0.0058 0.003 0.0022
Schistosoma mansoni endoplasmin 0.0499 0.3936 0.4858
Trichomonas vaginalis heat shock protein, putative 0.0499 0.3936 1
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0452 0.055
Schistosoma mansoni hypothetical protein 0.0083 0.025 0.03
Plasmodium vivax unspecified product 0.0155 0.0887 0.2195
Leishmania major developmentally regulated phosphoprotein-like protein 0.0341 0.2543 0.6433
Echinococcus granulosus epidermal growth factor receptor 0.0599 0.4822 0.4818
Trichomonas vaginalis AGC family protein kinase 0.0103 0.0428 0.104
Schistosoma mansoni tyrosine kinase 0.0478 0.3755 0.4634
Entamoeba histolytica tyrosin kinase, putative 0.0058 0.003 0.0076
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0058 0.003 0.0032
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0413 0.0502
Brugia malayi C-terminal src kinase protein 1 0.0058 0.003 0.0032
Plasmodium falciparum serine/threonine protein kinase, putative 0.0247 0.1702 0.4282
Schistosoma mansoni casein kinase II beta subunit 0.0075 0.018 0.0213
Plasmodium vivax DNA topoisomerase II, putative 0.0112 0.0513 0.1238
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus multilocularis calcium activated potassium channel 0.0101 0.0413 0.0502
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus multilocularis protein kinase shaggy 0.0115 0.0541 0.0659
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0865 0.106
Trypanosoma brucei heat shock protein, putative 0.0499 0.3936 1
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Giardia lamblia Kinase, CMGC CDK 0.0105 0.0452 0.1081
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.006 0.0051 0.0055
Echinococcus multilocularis mitogen activated protein kinase 3 0.0121 0.0593 0.0724
Toxoplasma gondii heat shock protein 75, putative 0.0199 0.1279 0.3199
Echinococcus multilocularis neuroglian 0.0147 0.0818 0.1002
Echinococcus granulosus tyrosine protein kinase Src64B 0.0131 0.0676 0.0669
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0101 0.0416 0.0591
Brugia malayi protein-tyrosine kinase 0.0102 0.0424 0.0602
Schistosoma mansoni protein kinase 0.0058 0.003 0.0027
Loa Loa (eye worm) TK/FER protein kinase 0.0058 0.003 0.0032
Schistosoma mansoni kinase 0.0116 0.0543 0.0662
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0452 0.055
Brugia malayi Kinase associated domain 1 family protein 0.0083 0.025 0.0351
Loa Loa (eye worm) serine/threonine protein kinase 0.0058 0.003 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0155 0.0887 0.2213
Loa Loa (eye worm) hypothetical protein 0.008 0.0231 0.0322
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0112 0.0513 0.0625
Plasmodium vivax serine/threonine-specific protein kinase, putative 0.0225 0.1513 0.3797
Echinococcus multilocularis activin receptor type 0.0076 0.0193 0.0229
Loa Loa (eye worm) hypothetical protein 0.0125 0.0625 0.0892
Brugia malayi Cyclin, N-terminal domain containing protein 0.0065 0.0095 0.0126
Toxoplasma gondii heat shock protein 90, putative 0.0499 0.3936 1
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0139 0.0752 0.092
Plasmodium falciparum heat shock protein 90, putative 0.0199 0.1279 0.3199
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus multilocularis protein tyrosine kinase 0.0571 0.4575 0.5649
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0199 0.1279 0.3251
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.052 0.1275
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Schistosoma mansoni protein kinase 0.0076 0.0193 0.0229
Echinococcus granulosus serine:threonine protein kinase PLK1 0.021 0.1382 0.1375
Echinococcus granulosus growth factor receptor bound protein 2 0.0076 0.0193 0.0186
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0112 0.0513 0.1257
Schistosoma mansoni hypothetical protein 0.0058 0.003 0.0027
Trypanosoma brucei protein kinase, putative 0.0076 0.0193 0.0417
Loa Loa (eye worm) heat shock protein 90 0.0499 0.3936 0.5681
Brugia malayi Protein kinase domain containing protein 0.0349 0.2608 0.3761
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0101 0.0413 0.0406
Schistosoma mansoni protein kinase 0.0058 0.003 0.0027
Echinococcus multilocularis tyrosine kinase 0.0058 0.003 0.0027
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0076 0.0193 0.0417
Echinococcus multilocularis epidermal growth factor receptor 0.0599 0.4822 0.5953
Toxoplasma gondii AGC kinase 0.0099 0.0391 0.0926
Schistosoma mansoni tyrosine kinase 0.04 0.3064 0.378
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0139 0.0752 0.092
Trypanosoma cruzi cyclin, putative 0.0065 0.0095 0.0167
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus multilocularis serine:threonine protein kinase 38 0.0057 0.0021 0.0017
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0115 0.0541 0.0659
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0341 0.2543 0.2537
Echinococcus multilocularis roundabout 2 0.0167 0.0996 0.1222
Schistosoma mansoni dual specificity serine/threonine tyrosine kinase 0.0165 0.0976 0.1197
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0102 0.0424 0.1078
Trichomonas vaginalis receptor histidine kinase, putative 0.0112 0.0513 0.1257
Schistosoma mansoni cyclin B 0.0065 0.0095 0.0108
Giardia lamblia Kinase, PLK 0.021 0.1382 0.3461
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Brugia malayi Sex muscle abnormal protein 5 0.0073 0.0165 0.0227
Echinococcus granulosus heat shock protein 90 0.0499 0.3936 0.3931
Schistosoma mansoni serine/threonine protein kinase 0.021 0.1382 0.1699
Trypanosoma brucei cdc2-related kinase 1 0.0105 0.0452 0.1081
Schistosoma mansoni tyrosine kinase 0.0131 0.0676 0.0827
Echinococcus granulosus mitogen activated protein kinase 3 0.0121 0.0593 0.0586
Brugia malayi Hr1 repeat family protein 0.0057 0.0021 0.002
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0057 0.0022 0.0014
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0058 0.003 0.0027
Brugia malayi Endoplasmin precursor 0.0499 0.3936 0.5681
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Plasmodium vivax protein kinase Crk2 0.0105 0.0452 0.1081
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0057 0.0021 0.0017
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Brugia malayi Serine/threonine-protein kinase Nek7 0.0439 0.3404 0.4911
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Loa Loa (eye worm) AGC/NDR protein kinase 0.0057 0.0021 0.002
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Onchocerca volvulus 0.0102 0.0424 0.0684
Echinococcus granulosus tyrosine protein kinase Fyn 0.0131 0.0676 0.0669
Brugia malayi GSG2 0.0139 0.0752 0.1076
Trypanosoma cruzi heat shock protein 85, putative 0.0386 0.2941 0.7453
Trypanosoma brucei heat shock protein, putative 0.0499 0.3936 1
Entamoeba histolytica protein kinase domain containing protein 0.0247 0.1702 0.4325
Trichomonas vaginalis AGC family protein kinase 0.0103 0.0428 0.104
Entamoeba histolytica cell division protein kinase 2, putative 0.0105 0.0452 0.1149
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0247 0.1702 0.4282
Echinococcus granulosus endoplasmin 0.0386 0.2941 0.2936
Echinococcus granulosus tyrosine protein kinase ABL1 0.0523 0.4149 0.4145
Plasmodium vivax heat shock protein 86, putative 0.0499 0.3936 1
Trichomonas vaginalis TKL family protein kinase 0.006 0.0051 0.0075
Loa Loa (eye worm) TK protein kinase 0.0058 0.003 0.0032
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0112 0.0513 0.1238
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Schistosoma mansoni DNA topoisomerase II 0.0112 0.0513 0.0625
Onchocerca volvulus 0.0102 0.0424 0.0684
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0073 0.0165 0.0227
Trichomonas vaginalis cyclins, putative 0.0065 0.0095 0.0189
Echinococcus granulosus c src tyrosine kinase 0.0131 0.0676 0.0669
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Echinococcus granulosus cyclin dependent kinase 1 0.0105 0.0452 0.0445
Loa Loa (eye worm) hypothetical protein 0.013 0.0666 0.0953
Brugia malayi Protein kinase domain containing protein 0.0102 0.0424 0.0602
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Entamoeba histolytica serine/threonine kinase, putative 0.0058 0.003 0.0076
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Brugia malayi serine/threonine-protein kinase PAK 7 0.039 0.2976 0.4293
Echinococcus multilocularis cyclin dependent kinase 0.0105 0.0452 0.055
Giardia lamblia G2/mitotic-specific cyclin B 0.0065 0.0095 0.0167
Giardia lamblia Heat shock protein HSP 90-alpha 0.0386 0.2941 0.7453
Entamoeba histolytica protein kinase domain containing protein 0.0115 0.0541 0.1374
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0058 0.003 0.0027
Schistosoma mansoni tyrosine kinase 0.0968 0.8093 1
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0105 0.0452 0.0643
Trypanosoma brucei aurora B kinase 0.0247 0.1702 0.4282
Echinococcus multilocularis integrin linked protein kinase 0.0058 0.003 0.0027
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.008 0.0231 0.0276
Onchocerca volvulus Dual specificity protein kinase TTK homolog 0.0165 0.0976 0.1634
Trypanosoma cruzi heat shock protein 90, putative 0.0386 0.2941 0.7453
Echinococcus multilocularis receptor type guanylyl cyclase 0.0058 0.003 0.0027
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.0424 0.0602
Trichomonas vaginalis CMGC family protein kinase 0.0134 0.0701 0.1738
Trichomonas vaginalis heat shock protein, putative 0.0386 0.2941 0.7459
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0073 0.0165 0.0227
Echinococcus granulosus cyclin dependent kinase 0.0105 0.0452 0.0445
Brugia malayi hypothetical protein 0.0125 0.0625 0.0892
Echinococcus multilocularis casein kinase ii subunit alpha 0.0155 0.0887 0.1088
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0153 0.018
Trypanosoma brucei heat shock protein, putative 0.0499 0.3936 1
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0057 0.0021 0.0013
Entamoeba histolytica DNA topoisomerase II, putative 0.0112 0.0513 0.1304
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0057 0.0022 0.0017
Trypanosoma cruzi cyclin, putative 0.0065 0.0095 0.0167
Leishmania major mitochondrial DNA topoisomerase II 0.0112 0.0513 0.1238
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.052 0.1275
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Onchocerca volvulus 0.0058 0.003 0.0005
Loa Loa (eye worm) haspin protein kinase 0.0158 0.0915 0.1312
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Echinococcus granulosus tyrosine kinase 0.0102 0.0424 0.0417
Brugia malayi Cyclin, N-terminal domain containing protein 0.0065 0.0095 0.0126
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0058 0.003 0.0022
Echinococcus granulosus raf serine:threonine protein kinase 0.007 0.0139 0.0131
Schistosoma mansoni tyrosine protein kinase 0.0058 0.003 0.0027
Brugia malayi Protein kinase domain containing protein 0.0102 0.0424 0.0602
Trichomonas vaginalis AGC family protein kinase 0.0103 0.0428 0.104
Echinococcus multilocularis mitogen activated protein kinase 11 0.0274 0.1947 0.2399
Echinococcus granulosus insulin receptor 0.0683 0.5567 0.5564
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0452 0.1101
Trichomonas vaginalis CAMK family protein kinase 0.0234 0.1595 0.402
Leishmania major cyclin 0.0065 0.0095 0.0167
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0058 0.003 0.0032
Entamoeba histolytica protein kinase, putative 0.0247 0.1702 0.4325
Entamoeba histolytica protein kinase, putative 0.0099 0.0391 0.0994
Echinococcus granulosus fibroblast growth factor receptor 4 0.0259 0.181 0.1804
Loa Loa (eye worm) hypothetical protein 0.0058 0.003 0.0032
Echinococcus multilocularis tyrosine protein kinase HCK 0.0058 0.003 0.0027
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0121 0.0593 0.0847
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trypanosoma brucei Casein kinase II 0.0155 0.0887 0.2195
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0021 0.0017
Trichomonas vaginalis cyclins, putative 0.0065 0.0095 0.0189
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0247 0.1702 0.2096
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0102 0.0424 0.0515
Brugia malayi protein kinase C II. 0.0072 0.0153 0.021
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0058 0.003 0.0022
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0131 0.0676 0.0827
Entamoeba histolytica tyrosin kinase, putative 0.0058 0.003 0.0076
Plasmodium vivax DNA gyrase subunit B, putative 0.0112 0.0513 0.1238
Echinococcus granulosus NCK adaptor protein 0.0073 0.0165 0.0157
Echinococcus multilocularis tyrosine protein kinase csk 0.0058 0.003 0.0027
Echinococcus granulosus cyclin B 0.0065 0.0095 0.0087
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.039 0.2976 0.4293
Onchocerca volvulus 0.0058 0.003 0.0005
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0058 0.003 0.0032
Schistosoma mansoni protein kinase 0.0058 0.003 0.0027
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0058 0.003 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0274 0.1947 0.4909
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1382 0.3475
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.0424 0.0602
Loa Loa (eye worm) hypothetical protein 0.0125 0.0625 0.0892
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.006 0.0051 0.0054
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0057 0.0021 0.0013
Trichomonas vaginalis protein tyrosine kinase, putative 0.0058 0.003 0.0022
Trypanosoma brucei developmentally regulated phosphoprotein 0.0341 0.2543 0.6433
Schistosoma mansoni atypical protein kinase C 0.0069 0.013 0.0152
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0131 0.0676 0.0827
Echinococcus multilocularis protein kinase 0.0058 0.003 0.0027
Loa Loa (eye worm) TK/FER protein kinase 0.0058 0.003 0.0032
Loa Loa (eye worm) hypothetical protein 0.013 0.0666 0.0953
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0085 0.027 0.0614
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Echinococcus multilocularis kinase suppressor of Ras 1 0.0058 0.003 0.0027
Echinococcus granulosus protein tyrosine kinase 0.0571 0.4575 0.4571
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0683 0.5567 0.5564
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0341 0.2543 0.6433
Loa Loa (eye worm) TK/FER protein kinase 0.0058 0.003 0.0032
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0385 0.2925 0.3608
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0131 0.0676 0.0827
Brugia malayi Hsp90 protein 0.0199 0.1279 0.1839
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0112 0.0513 0.0506
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0125 0.0625 0.0763
Loa Loa (eye worm) hypothetical protein 0.0291 0.2097 0.3021
Schistosoma mansoni tyrosine kinase 0.0599 0.4822 0.5953
Brugia malayi Guanylyl cyclase protein 23 0.0058 0.003 0.0032
Entamoeba histolytica hypothetical protein 0.0058 0.003 0.0076
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.006 0.0051 0.0044
Plasmodium falciparum endoplasmin, putative 0.0311 0.2274 0.5746
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0105 0.0452 0.0445
Loa Loa (eye worm) TK/INSR protein kinase 0.0683 0.5567 0.804
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Plasmodium falciparum DNA gyrase subunit B 0.0112 0.0513 0.1238
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0593 0.1461
Trypanosoma cruzi cyclin 6, putative 0.0065 0.0095 0.0167
Chlamydia trachomatis serine/threonine protein kinase 0.0439 0.3404 1
Trypanosoma cruzi rac serine-threonine kinase, putative 0.006 0.0051 0.0055
Schistosoma mansoni protein kinase 0.0058 0.003 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Plasmodium falciparum protein kinase, putative 0.0225 0.1513 0.3797
Loa Loa (eye worm) RGC/RGC protein kinase 0.0058 0.003 0.0032
Loa Loa (eye worm) TOPoisomerase family member 0.0112 0.0513 0.0731
Brugia malayi Tyrosine-protein kinase abl-1 0.026 0.1819 0.262
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Onchocerca volvulus 0.0058 0.003 0.0005
Schistosoma mansoni serine/threonine-protein kinase 0.0064 0.0089 0.01
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Echinococcus granulosus RNA directed DNA polymerase 0.008 0.0231 0.0223
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0131 0.0676 0.0827
Giardia lamblia Aurora kinase 0.0247 0.1702 0.4282
Echinococcus multilocularis casein kinase ii subunit beta 0.0075 0.018 0.0213
Trichomonas vaginalis cyclins, putative 0.0065 0.0095 0.0189
Echinococcus granulosus tyrosine protein kinase Src42A 0.0131 0.0676 0.0669
Schistosoma mansoni serine/threonine protein kinase 0.0385 0.2925 0.3608
Entamoeba histolytica protein kinase, putative 0.0103 0.0428 0.1088
Entamoeba histolytica protein kinase domain containing protein 0.0155 0.0887 0.2255
Schistosoma mansoni pyruvate dehydrogenase 0.0229 0.1548 0.1905
Trypanosoma brucei heat shock protein 90, putative 0.0499 0.3936 1
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0199 0.1279 0.1573
Brugia malayi Immunoglobulin I-set domain containing protein 0.0836 0.6922 1
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0234 0.0544
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0057 0.0021 0.0017
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0058 0.003 0.0027
Brugia malayi Probable DNA topoisomerase II 0.0112 0.0513 0.0731
Echinococcus granulosus activated cdc42 kinase 1 0.0394 0.3012 0.3006
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0247 0.1702 0.4325
Echinococcus granulosus tyrosine protein kinase 0.0058 0.003 0.0022
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0058 0.003 0.0022
Toxoplasma gondii heat shock protein HSP90 0.0499 0.3936 1
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0131 0.0676 0.0827
Echinococcus multilocularis protein kinase c iota type 0.0069 0.013 0.0152
Toxoplasma gondii ck2 beta subunit 0.0075 0.018 0.0384
Trichomonas vaginalis AGC family protein kinase 0.0247 0.1702 0.4294
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0593 0.0724
Trypanosoma cruzi Protein kinase B 0.0064 0.0089 0.015
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0058 0.003 0.0027
Onchocerca volvulus 0.0633 0.5127 0.8786
Schistosoma mansoni tyrosine kinase 0.0924 0.7699 0.9512
Echinococcus multilocularis activated cdc42 kinase 1 0.0394 0.3012 0.3715
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0112 0.0513 0.0731
Schistosoma mansoni vesicular amine transporter 0.0125 0.0625 0.0763
Brugia malayi Variant SH3 domain containing protein 0.0073 0.0165 0.0227
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.0032
Trichomonas vaginalis heat shock protein, putative 0.0386 0.2941 0.7459
Loa Loa (eye worm) heat shock protein 75 0.0199 0.1279 0.1839
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0131 0.0676 0.0827
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0836 0.6922 1
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0076 0.0193 0.0185
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0125 0.0625 0.0763
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus granulosus tyrosine kinase 0.0102 0.0424 0.0417
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Loa Loa (eye worm) TK/FER protein kinase 0.0058 0.003 0.0032
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0115 0.0541 0.0771
Loa Loa (eye worm) TK/FER protein kinase 0.0102 0.0424 0.0602
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0058 0.003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0219 0.1454 0.2092
Echinococcus multilocularis CDC7 cell division cycle 7 0.0134 0.0701 0.0858
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Entamoeba histolytica protein kinase, putative 0.0225 0.1513 0.3844
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0057 0.0021 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0413 0.0502
Trypanosoma brucei heat shock protein, putative 0.0499 0.3936 1
Giardia lamblia Kinase, TTK 0.0165 0.0976 0.2422
Plasmodium falciparum protein kinase 5 0.0105 0.0452 0.1081
Echinococcus multilocularis heat shock protein 0.0499 0.3936 0.4858
Loa Loa (eye worm) hypothetical protein 0.0087 0.0289 0.0407
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0359 0.2694 0.2689
Leishmania major protein kinase, putative 0.0247 0.1702 0.4282
Echinococcus multilocularis heat shock protein 90 0.0499 0.3936 0.4858
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Trichomonas vaginalis AGC family protein kinase 0.0061 0.0058 0.0095
Loa Loa (eye worm) hypothetical protein 0.0083 0.025 0.0351
Trichomonas vaginalis AGC family protein kinase 0.0247 0.1702 0.4294
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Brugia malayi SH2 domain containing protein 0.0102 0.0424 0.0602
Trichomonas vaginalis sensor histidine kinase, putative 0.0112 0.0513 0.1257
Echinococcus granulosus MAM 0.0057 0.0027 0.0019
Loa Loa (eye worm) hypothetical protein 0.0057 0.0021 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.003 0.0027
Schistosoma mansoni tyrosine kinase 0.0571 0.4575 0.5649
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0075 0.018 0.0384
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0075 0.018 0.0457
Echinococcus granulosus tyrosine protein kinase Fyn 0.0131 0.0676 0.0669
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0087 0.0221
Loa Loa (eye worm) hypothetical protein 0.0167 0.0996 0.1429
Plasmodium vivax casein kinase II beta chain, putative 0.0075 0.018 0.0384
Loa Loa (eye worm) TK/FAK protein kinase 0.0577 0.4629 0.6683
Loa Loa (eye worm) haspin protein kinase 0.0139 0.0752 0.1076
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Entamoeba histolytica protein kinase, putative 0.0057 0.0021 0.0054
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0131 0.0676 0.0669
Schistosoma mansoni hypothetical protein 0.0139 0.0752 0.092
Entamoeba histolytica receptor protein kinase, putative 0.0058 0.003 0.0076
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Brugia malayi Protein kinase domain containing protein 0.0103 0.0428 0.0608
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Trypanosoma cruzi cdc2-related kinase 3 0.0105 0.0452 0.1081
Echinococcus granulosus tyrosine protein kinase Srms 0.0102 0.0424 0.0417
Schistosoma mansoni tyrosine kinase 0.009 0.0312 0.0376
Echinococcus granulosus Protein kinase C brain isozyme 0.0152 0.0865 0.0858
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0076 0.0193 0.0417
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.021 0.1382 0.1699
Trypanosoma brucei mitotic cyclin 6 0.0065 0.0095 0.0167
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0359 0.2695 0.3886
Trypanosoma cruzi myosin heavy chain kinase A, putative 0.0065 0.0091 0.0157
Echinococcus multilocularis heat shock protein 70 0.0058 0.003 0.0028
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0341 0.2543 0.3135
Schistosoma mansoni tyrosine kinase 0.0683 0.5567 0.6876
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0075 0.018 0.0263
Plasmodium vivax heat shock protein 90, putative 0.0199 0.1279 0.3199
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0541 0.1327
Echinococcus granulosus activated cdc42 kinase 1 0.0394 0.3012 0.3006
Echinococcus granulosus activin receptor type 0.0076 0.0193 0.0185
Echinococcus granulosus defective proboscis extension response 0.0125 0.0625 0.0617
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0057 0.0021 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Trypanosoma cruzi cdc2-related kinase 1 0.0105 0.0452 0.1081
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0051 0.0075
Echinococcus granulosus mitogen activated protein kinase 0.0121 0.0593 0.0586
Loa Loa (eye worm) hypothetical protein 0.0058 0.003 0.0032
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0386 0.2941 1
Echinococcus multilocularis protein KINase family member (kin 25) 0.0187 0.1178 0.1447
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0057 0.0021 0.0013
Loa Loa (eye worm) hypothetical protein 0.0145 0.0803 0.115
Echinococcus multilocularis aurora kinase A 0.0247 0.1702 0.2096
Brugia malayi Protein kinase domain containing protein 0.0057 0.0021 0.002
Echinococcus granulosus N chimaerin 0.0057 0.0022 0.0014
Entamoeba histolytica serine/threonine kinase, putative 0.0058 0.003 0.0076
Echinococcus multilocularis Immunoglobulin 0.0125 0.0625 0.0763
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Schistosoma mansoni ephrin receptor 0.0058 0.003 0.0027
Loa Loa (eye worm) hypothetical protein 0.0125 0.0625 0.0892
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0131 0.0676 0.0827
Loa Loa (eye worm) hypothetical protein 0.0058 0.003 0.0032
Trypanosoma brucei polo-like protein kinase 0.021 0.1382 0.3461
Onchocerca volvulus 0.0058 0.003 0.0005
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0342 0.2551 0.2546
Schistosoma mansoni serine/threonine protein kinase 0.0342 0.2551 0.3146
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0199 0.1279 0.1273
Schistosoma mansoni serine/threonine RGC 0.0058 0.003 0.0027
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Trichomonas vaginalis CMGC family protein kinase 0.0134 0.0701 0.1738
Brugia malayi P38 map kinase family protein 2 0.0274 0.1947 0.2805
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Schistosoma mansoni protein kinase 0.0402 0.3081 0.3801
Loa Loa (eye worm) hypothetical protein 0.0112 0.0513 0.0731
Echinococcus multilocularis serine:threonine protein kinase N2 0.0057 0.0021 0.0017
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Loa Loa (eye worm) hypothetical protein 0.0112 0.0513 0.0731
Echinococcus granulosus CDC7 cell division cycle 7 0.0134 0.0701 0.0694
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.008 0.0223 0.0215
Trichomonas vaginalis endoplasmin, putative 0.0311 0.2274 0.5756
Entamoeba histolytica tyrosine kinase, putative 0.0058 0.003 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.003 0.0022
Brugia malayi integrin-linked kinase 0.0058 0.003 0.0032
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0131 0.0676 0.0827
Plasmodium vivax glycogen synthase kinase 3, putative 0.0115 0.0541 0.1308
Loa Loa (eye worm) RGC/RGC protein kinase 0.0058 0.003 0.0032
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0155 0.0887 0.2195
Echinococcus granulosus dual specificity serine:threonine tyrosine 0.0165 0.0976 0.0969
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0085 0.027 0.0614
Echinococcus granulosus serine:threonine protein kinase N2 0.0057 0.0021 0.0013
Echinococcus multilocularis tyrosine protein kinase csk 0.0058 0.003 0.0027
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trichomonas vaginalis casein kinase II beta chain, putative 0.0075 0.018 0.0406
Leishmania major DNA topoisomerase ii 0.0112 0.0513 0.1238
Brugia malayi serine/threonine-protein kinase plk-2 0.021 0.1382 0.1987
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0121 0.0593 0.1442
Entamoeba histolytica protein kinase, putative 0.0103 0.0428 0.1088
Brugia malayi map kinase activated protein kinase protein 2 0.0385 0.2925 0.4219
Brugia malayi SH2 domain containing protein 0.0102 0.0424 0.0602
Loa Loa (eye worm) Csnk2b protein 0.0075 0.018 0.0249
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Schistosoma mansoni tyrosine kinase 0.0683 0.5567 0.6876
Echinococcus granulosus casein kinase ii subunit beta 0.0075 0.018 0.0172
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0247 0.1702 0.1696
Schistosoma mansoni protein kinase 0.0155 0.0887 0.1088
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0115 0.0541 0.1308
Trichomonas vaginalis STE family protein kinase 0.0225 0.1513 0.3811
Schistosoma mansoni serine/threonine-protein kinase 0.0064 0.0089 0.01
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0247 0.1702 0.4325
Echinococcus granulosus mitogen activated protein kinase 14 0.0274 0.1947 0.1941
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Entamoeba histolytica protein kinase domain containing protein 0.0115 0.0541 0.1374
Trypanosoma cruzi heat shock protein 90, putative 0.0499 0.3936 1
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Brugia malayi Tyrosine-protein kinase PR2 0.0058 0.003 0.0032
Plasmodium falciparum casein kinase 2, alpha subunit 0.0155 0.0887 0.2195
Toxoplasma gondii aurora kinase 0.0247 0.1702 0.4282
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.003 0.0076
Brugia malayi hypothetical protein 0.0139 0.0752 0.1076
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0112 0.0513 0.1238
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0058 0.003 0.0027
Echinococcus multilocularis tyrosine kinase 0.0102 0.0424 0.0515
Brugia malayi Protein kinase domain containing protein 0.0165 0.0976 0.14
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0121 0.0593 0.1442
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Echinococcus granulosus calcium activated potassium channel 0.0101 0.0413 0.0406
Loa Loa (eye worm) hypothetical protein 0.0093 0.034 0.048
Loa Loa (eye worm) TK/CSK protein kinase 0.0058 0.003 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0058 0.003 0.0032
Loa Loa (eye worm) hypothetical protein 0.0073 0.0165 0.0227
Trichomonas vaginalis AGC family protein kinase 0.0247 0.1702 0.4294
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Leishmania major heat shock protein 83-1 0.0499 0.3936 1
Brugia malayi Protein kinase domain containing protein 0.0102 0.0424 0.0602
Loa Loa (eye worm) NEK/NEK6 protein kinase 0.0439 0.3404 0.4911
Echinococcus multilocularis insulin receptor 0.0683 0.5567 0.6876
Echinococcus granulosus tyrosine kinase 0.0058 0.003 0.0022
Entamoeba histolytica serine/threonine kinase, putative 0.0058 0.003 0.0076
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0274 0.1947 0.4909
Trypanosoma cruzi heat shock protein 85, putative 0.0499 0.3936 1
Entamoeba histolytica hypothetical protein 0.0058 0.003 0.0076
Onchocerca volvulus 0.0102 0.0424 0.0684
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0021 0.0017
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0058 0.003 0.0076
Entamoeba histolytica heat shock protein 90, putative 0.0499 0.3936 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0058 0.003 0.0076
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0274 0.1947 0.2805
Entamoeba histolytica hypothetical protein 0.0058 0.0032 0.0081
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0063 0.0076 0.0192
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0593 0.1461
Loa Loa (eye worm) AGC/PKN protein kinase 0.0057 0.0021 0.002
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0058 0.003 0.0032
Trichomonas vaginalis heat shock protein, putative 0.0311 0.2274 0.5756
Entamoeba histolytica protein kinase, putative 0.0058 0.0032 0.0081
Entamoeba histolytica heat shock protein 90, putative 0.0499 0.3936 1
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0061 0.0059 0.0051
Echinococcus granulosus serine/threonine protein kinase 0.0064 0.0089 0.0081
Schistosoma mansoni protein tyrosine kinase 0.0058 0.003 0.0027
Loa Loa (eye worm) TK protein kinase 0.0058 0.003 0.0032
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Echinococcus granulosus NDR protein kinase 0.0057 0.0021 0.0013
Brugia malayi MHCK/EF2 kinase domain family protein 0.0065 0.0091 0.0121
Echinococcus multilocularis eukaryotic elongation factor 2 kinase 0.0065 0.0091 0.0103
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0058 0.003 0.0027
Schistosoma mansoni protein kinase 0.0076 0.0193 0.0229
Brugia malayi Immunoglobulin I-set domain containing protein 0.0125 0.0625 0.0892
Giardia lamblia Kinase, CMGC GSK 0.0115 0.0541 0.1308
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0593 0.1461
Trichomonas vaginalis CAMK family protein kinase 0.021 0.1382 0.3475
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0105 0.0452 0.0643
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0112 0.0513 0.1257
Trichomonas vaginalis AGC family protein kinase 0.0058 0.003 0.0022
Loa Loa (eye worm) TK protein kinase 0.0058 0.003 0.0032
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Echinococcus multilocularis mitogen activated protein kinase 11 0.0274 0.1947 0.2399
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Echinococcus multilocularis raf serine:threonine protein kinase 0.007 0.0139 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0051 0.0075
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0058 0.003 0.0032
Echinococcus multilocularis tyrosine protein kinase shark 0.0968 0.8093 1
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0185 0.1156 0.1421
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0058 0.003 0.0027
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0058 0.003 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0058 0.003 0.0022
Trichomonas vaginalis CMGC family protein kinase 0.0155 0.0887 0.2213
Loa Loa (eye worm) TK protein kinase 0.0058 0.003 0.0032
Entamoeba histolytica protein kinase, putative 0.0058 0.003 0.0076
Echinococcus multilocularis mitogen activated protein kinase 14 0.0274 0.1947 0.2399
Loa Loa (eye worm) hypothetical protein 0.0125 0.0625 0.0892

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 2.5119 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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