Detailed information for compound 1486391

Basic information

Technical information
  • TDR Targets ID: 1486391
  • Name: N-[[3-ethoxy-4-(thiophen-2-ylmethoxy)phenyl]m ethyl]ethanamine
  • MW: 291.408 | Formula: C16H21NO2S
  • H donors: 1 H acceptors: 0 LogP: 3.18 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCNCc1ccc(c(c1)OCC)OCc1cccs1
  • InChi: 1S/C16H21NO2S/c1-3-17-11-13-7-8-15(16(10-13)18-4-2)19-12-14-6-5-9-20-14/h5-10,17H,3-4,11-12H2,1-2H3
  • InChiKey: NQKVBANGTFUXBO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[[3-ethoxy-4-(2-thienylmethoxy)phenyl]methyl]ethanamine
  • [3-ethoxy-4-(2-thienylmethoxy)benzyl]-ethyl-amine
  • MLS000771939
  • SMR000376483

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus protein kinase 0.0094 0.008 0.0067
Entamoeba histolytica heat shock protein 90, putative 0.0738 0.355 1
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Entamoeba histolytica protein kinase domain containing protein 0.0403 0.1744 0.4893
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0198 0.064 0.1615
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0167 0.0472 0.0459
Loa Loa (eye worm) hypothetical protein 0.0106 0.0145 0.0208
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0094 0.008 0.0096
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Loa Loa (eye worm) hypothetical protein 0.0093 0.0071 0.0103
Loa Loa (eye worm) TK/FER protein kinase 0.0094 0.008 0.0115
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Entamoeba histolytica cyclin, putative 0.0106 0.0145 0.0372
Loa Loa (eye worm) hypothetical protein 0.0212 0.0713 0.1028
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0165 0.0461 0.0554
Loa Loa (eye worm) hypothetical protein 0.0204 0.0672 0.0968
Brugia malayi Casein kinase II, alpha chain 0.0253 0.0933 0.1328
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0204 0.0672 0.0814
Echinococcus granulosus ephrin type A receptor 4 A 0.0094 0.008 0.0067
Loa Loa (eye worm) hypothetical protein 0.0094 0.008 0.0115
Brugia malayi Variant SH3 domain containing protein 0.0119 0.0214 0.029
Brugia malayi Cyclin, N-terminal domain containing protein 0.0106 0.0145 0.019
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0214 0.0723 0.0877
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0198 0.064 0.1615
Loa Loa (eye worm) TK/INSR protein kinase 0.1116 0.5589 0.8057
Echinococcus multilocularis tyrosine protein kinase csk 0.0094 0.008 0.0082
Trypanosoma brucei heat shock protein, putative 0.0738 0.355 1
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0098 0.0101 0.0062
Loa Loa (eye worm) hypothetical protein 0.0094 0.008 0.0115
Brugia malayi Immunoglobulin I-set domain containing protein 0.0204 0.0672 0.0951
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Echinococcus multilocularis mitogen activated protein kinase 14 0.0448 0.1988 0.2441
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Loa Loa (eye worm) protein kinase domain-containing protein 0.0094 0.008 0.0115
Entamoeba histolytica serine/threonine kinase, putative 0.0094 0.008 0.0188
Schistosoma mansoni vav2 0.01 0.0109 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Brugia malayi Receptor family ligand binding region containing protein 0.0094 0.008 0.0096
Brugia malayi Protein kinase domain containing protein 0.0586 0.2732 0.3926
Schistosoma mansoni ephrin receptor 0.0094 0.008 0.0082
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0168 0.0476 0.0668
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Brugia malayi serine/threonine kinase 12 0.0403 0.1744 0.2499
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0168 0.0476 0.1308
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Toxoplasma gondii aurora kinase 0.0403 0.1744 0.4795
Echinococcus granulosus activated cdc42 kinase 1 0.0645 0.3047 0.3037
Entamoeba histolytica cell division protein kinase 2, putative 0.0212 0.0712 0.1976
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0403 0.1744 0.4795
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.064 0.1773
Schistosoma mansoni heat shock protein 0.0738 0.355 0.4372
Giardia lamblia Kinase, CMGC MAPK 0.0198 0.064 0.1773
Trichomonas vaginalis heat shock protein, putative 0.057 0.2645 0.7441
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Echinococcus granulosus neuroglian 0.024 0.0864 0.0852
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0198 0.064 0.1615
Loa Loa (eye worm) PEK/PEK protein kinase 0.0657 0.3115 0.4491
Echinococcus granulosus serine:threonine protein kinase haspin 0.0228 0.0798 0.0786
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Trichomonas vaginalis receptor histidine kinase, putative 0.0168 0.0476 0.1308
Giardia lamblia Kinase, NEK 0.0094 0.008 0.0188
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0168 0.0476 0.1308
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0344 0.1425 0.1745
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0198 0.064 0.1615
Schistosoma mansoni protein kinase 0.0124 0.0242 0.0283
Schistosoma mansoni hypothetical protein 0.0094 0.0077 0.0079
Trypanosoma brucei cdc2-related kinase 1 0.0172 0.05 0.1211
Loa Loa (eye worm) heat shock protein 90 0.0738 0.355 0.5117
Loa Loa (eye worm) TK protein kinase 0.0094 0.008 0.0115
Schistosoma mansoni heat shock protein 0.0738 0.355 0.4372
Trichomonas vaginalis cyclins, putative 0.0106 0.0145 0.0372
Echinococcus granulosus retinal guanylyl cyclase 2 0.0094 0.008 0.0067
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Loa Loa (eye worm) TK/ABL protein kinase 0.0854 0.4179 0.6023
Trichomonas vaginalis CAMK family protein kinase 0.0344 0.1425 0.3991
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0093 0.0071 0.0103
Schistosoma mansoni tyrosine kinase 0.0172 0.0501 0.0602
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Echinococcus multilocularis cyclin dependent kinase 5 0.0172 0.05 0.0602
Echinococcus granulosus growth factor receptor bound protein 2 0.0125 0.0242 0.0229
Trypanosoma cruzi Protein kinase B 0.0105 0.0138 0.0168
Echinococcus granulosus RNA directed DNA polymerase 0.0131 0.0279 0.0267
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0124 0.0242 0.0229
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Schistosoma mansoni protein kinase 0.0094 0.008 0.0082
Echinococcus granulosus NDR protein kinase 0.0093 0.0071 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Schistosoma mansoni protein kinase 0.0094 0.008 0.0082
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0542 0.2495 0.3068
Entamoeba histolytica tyrosin kinase, putative 0.0094 0.008 0.0188
Trypanosoma cruzi polo-like protein kinase, putative 0.0344 0.1425 0.3876
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0198 0.064 0.1615
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Echinococcus granulosus cyclin dependent kinase 1 0.0172 0.05 0.0487
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Echinococcus multilocularis protein tyrosine kinase 0.0933 0.4602 0.5672
Trypanosoma cruzi cyclin 6, putative 0.0106 0.0145 0.0187
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0476 0.1309
Loa Loa (eye worm) hypothetical protein 0.0542 0.2495 0.3597
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0094 0.008 0.0096
Giardia lamblia Kinase, CMGC CDK 0.0172 0.05 0.1376
Loa Loa (eye worm) TK protein kinase 0.0167 0.0472 0.068
Echinococcus granulosus epidermal growth factor receptor 0.0748 0.3607 0.3599
Toxoplasma gondii heat shock protein 75, putative 0.0293 0.1153 0.3092
Schistosoma mansoni tyrosine kinase 0.0306 0.1222 0.1494
Entamoeba histolytica protein kinase, putative 0.0189 0.0588 0.1625
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0168 0.0476 0.1142
Trypanosoma cruzi cdc2-related kinase 3 0.0172 0.05 0.1211
Onchocerca volvulus 0.0094 0.008 0.0005
Echinococcus multilocularis casein kinase ii subunit alpha 0.0253 0.0933 0.1137
Echinococcus multilocularis MAM 0.0094 0.0077 0.0079
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0306 0.1222 0.121
Trichomonas vaginalis heat shock protein, putative 0.057 0.2645 0.7441
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Schistosoma mansoni hypothetical protein 0.0094 0.008 0.0082
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0253 0.0933 0.1345
Entamoeba histolytica receptor protein kinase, putative 0.0094 0.008 0.0188
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0189 0.0588 0.0711
Loa Loa (eye worm) TK/FAK protein kinase 0.0943 0.4656 0.6711
Echinococcus multilocularis insulin receptor 0.1116 0.5589 0.6893
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0403 0.1744 0.4893
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0586 0.2731 0.3359
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Trypanosoma cruzi Heat shock protein 83, putative 0.0738 0.355 1
Schistosoma mansoni serine/threonine protein kinase 0.0717 0.3437 0.4232
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0448 0.1988 0.5497
Echinococcus granulosus heat shock protein 90 0.0738 0.355 0.3542
Loa Loa (eye worm) hypothetical protein 0.0094 0.0077 0.0111
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0403 0.1744 0.4893
Giardia lamblia Kinase, TTK 0.0269 0.1021 0.2849
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Schistosoma mansoni tyrosine kinase 0.0748 0.3607 0.4443
Brugia malayi MAP kinase sur-1 0.0198 0.064 0.0906
Trichomonas vaginalis receptor histidine kinase, putative 0.0168 0.0476 0.1308
Entamoeba histolytica protein kinase domain containing protein 0.0189 0.0588 0.1625
Schistosoma mansoni tyrosine kinase 0.1116 0.5589 0.6893
Trypanosoma cruzi heat shock protein 85, putative 0.0738 0.355 1
Entamoeba histolytica DNA topoisomerase II, putative 0.0168 0.0476 0.1308
Giardia lamblia Aurora kinase 0.0403 0.1744 0.4893
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0094 0.008 0.0067
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0542 0.2495 0.2485
Plasmodium vivax hypothetical protein, conserved 0.0168 0.0476 0.1142
Giardia lamblia Heat shock protein HSP 90-alpha 0.057 0.2645 0.7441
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0119 0.0214 0.0308
Echinococcus multilocularis serine:threonine protein kinase N2 0.0093 0.0071 0.0072
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0098 0.0101 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0132 0.0283 0.0763
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0124 0.0242 0.0283
Schistosoma mansoni nephrin 0.024 0.0864 0.1051
Onchocerca volvulus 0.0094 0.008 0.0005
Plasmodium vivax heat shock protein 86, putative 0.0738 0.355 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0344 0.1425 0.2039
Trypanosoma cruzi casein kinase II, putative 0.0253 0.0933 0.2458
Loa Loa (eye worm) hypothetical protein 0.0094 0.008 0.0115
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0122 0.0229 0.043
Trypanosoma brucei heat shock protein, putative 0.0738 0.355 1
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0099 0.0102 0.0147
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0476 0.1309
Echinococcus multilocularis heat shock protein 70 0.0094 0.008 0.0083
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Onchocerca volvulus 0.0189 0.0588 0.0885
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0568 0.1568
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Schistosoma mansoni tyrosine kinase 0.0654 0.3098 0.3814
Entamoeba histolytica serine/threonine kinase, putative 0.0094 0.008 0.0188
Brugia malayi Protein kinase domain containing protein 0.0218 0.0748 0.1061
Loa Loa (eye worm) hypothetical protein 0.0167 0.0472 0.068
Echinococcus multilocularis tyrosine protein kinase Srms 0.0167 0.0472 0.0567
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Trypanosoma brucei heat shock protein, putative 0.0738 0.355 1
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0122 0.0229 0.043
Loa Loa (eye worm) TK/FER protein kinase 0.0167 0.0472 0.068
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.008 0.0188
Trichomonas vaginalis heat shock protein, putative 0.0461 0.2058 0.5781
Plasmodium vivax unspecified product 0.0253 0.0933 0.2458
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0122 0.0229 0.061
Schistosoma mansoni tyrosine kinase 0.0423 0.1851 0.2272
Plasmodium falciparum glycogen synthase kinase 3 0.0189 0.0588 0.1465
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0403 0.1744 0.4893
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Loa Loa (eye worm) TK/FER protein kinase 0.0167 0.0472 0.068
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0168 0.0476 0.0691
Giardia lamblia Grp94/Hsp90 0.057 0.2645 0.7441
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0094 0.008 0.0115
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Loa Loa (eye worm) hypothetical protein 0.0273 0.1041 0.15
Entamoeba histolytica hypothetical protein 0.0095 0.0082 0.0194
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Loa Loa (eye worm) RGC/RGC protein kinase 0.0094 0.008 0.0115
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0139 0.0318 0.0688
Echinococcus granulosus mitogen activated protein kinase 14 0.0448 0.1988 0.1977
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0124 0.0242 0.0467
Trichomonas vaginalis STE family protein kinase 0.0368 0.1556 0.4361
Trichomonas vaginalis sensor histidine kinase, putative 0.0168 0.0476 0.1308
Echinococcus multilocularis epidermal growth factor receptor 0.0978 0.4847 0.5976
Trichomonas vaginalis CAMK family protein kinase 0.0344 0.1425 0.3991
Trichomonas vaginalis cyclin B, putative 0.0106 0.0145 0.0372
Onchocerca volvulus 0.0094 0.008 0.0005
Echinococcus multilocularis serine:threonine protein kinase 38 0.0093 0.0071 0.0072
Loa Loa (eye worm) hypothetical protein 0.0204 0.0672 0.0968
Schistosoma mansoni protein kinase 0.0403 0.1744 0.2139
Echinococcus granulosus dual specificity serine:threonine tyrosine 0.0269 0.1021 0.1009
Trypanosoma cruzi heat shock protein 90, putative 0.0445 0.1968 0.5442
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0093 0.0072 0.0072
Entamoeba histolytica tyrosin kinase, putative 0.0094 0.008 0.0188
Echinococcus multilocularis tyrosine kinase 0.0094 0.008 0.0082
Trypanosoma brucei DNA topoisomerase ii 0.0168 0.0476 0.1142
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Echinococcus granulosus serine:threonine protein kinase haspin 0.0228 0.0798 0.0786
Loa Loa (eye worm) AGC/NDR protein kinase 0.0093 0.0071 0.0103
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Schistosoma mansoni tyrosine kinase 0.0146 0.036 0.0429
Echinococcus multilocularis heat shock protein 90 0.0738 0.355 0.4372
Loa Loa (eye worm) TK protein kinase 0.0094 0.008 0.0115
Schistosoma mansoni serine/threonine protein kinase 0.0403 0.1744 0.2139
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.008 0.0188
Echinococcus multilocularis tyrosine protein kinase csk 0.0094 0.008 0.0082
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0094 0.008 0.0115
Trichomonas vaginalis heat shock protein, putative 0.0293 0.1153 0.3222
Entamoeba histolytica protein kinase, putative 0.0403 0.1744 0.4893
Trichomonas vaginalis cyclins, putative 0.0106 0.0145 0.0372
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Echinococcus multilocularis serine threonine protein kinase 0.0368 0.1556 0.1907
Schistosoma mansoni protein kinase 0.0657 0.3115 0.3835
Echinococcus multilocularis tyrosine protein kinase csk 0.0094 0.008 0.0082
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0214 0.0723 0.071
Trichomonas vaginalis TKL family protein kinase 0.0098 0.01 0.0247
Loa Loa (eye worm) AUR protein kinase 0.0403 0.1744 0.2513
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Entamoeba histolytica casein kinase, putative 0.0253 0.0933 0.26
Echinococcus granulosus tyrosine protein kinase ABL1 0.0854 0.4179 0.4171
Echinococcus granulosus tyrosine protein kinase 0.0094 0.008 0.0067
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Echinococcus multilocularis mitogen activated protein kinase 11 0.0448 0.1988 0.2441
Loa Loa (eye worm) TK protein kinase 0.0094 0.008 0.0115
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0094 0.008 0.0188
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0172 0.05 0.1211
Trichomonas vaginalis CAMK family protein kinase 0.0344 0.1425 0.3991
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0168 0.0476 0.1308
Loa Loa (eye worm) hypothetical protein 0.0094 0.008 0.0115
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0933 0.26
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0093 0.0071 0.0058
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0403 0.1744 0.4893
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Trypanosoma brucei heat shock protein, putative 0.0738 0.355 1
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Loa Loa (eye worm) hypothetical protein 0.0135 0.0299 0.0431
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.008 0.0188
Entamoeba histolytica ankyrin repeat protein 0.0094 0.008 0.0188
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.064 0.1773
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.064 0.1773
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.056 0.2589 0.2579
Loa Loa (eye worm) hypothetical protein 0.0205 0.0674 0.0971
Echinococcus multilocularis cyclin dependent kinase 1 0.0172 0.05 0.0602
Loa Loa (eye worm) RGC/RGC protein kinase 0.0094 0.008 0.0115
Loa Loa (eye worm) RGC/RGC protein kinase 0.0094 0.008 0.0115
Brugia malayi Probable DNA topoisomerase II 0.0168 0.0476 0.0668
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0165 0.0461 0.0449
Trypanosoma brucei heat shock protein, putative 0.0738 0.355 1
Echinococcus granulosus heat shock protein 0.0738 0.355 0.3542
Trichomonas vaginalis AGC family protein kinase 0.0093 0.0071 0.0164
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0094 0.008 0.0096
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0204 0.0672 0.0814
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0094 0.008 0.0067
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0094 0.008 0.0067
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Echinococcus multilocularis mitogen activated protein kinase 11 0.0448 0.1988 0.2441
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Schistosoma mansoni hypothetical protein 0.0094 0.0077 0.0079
Echinococcus granulosus tyrosine protein kinase pr2 0.0094 0.008 0.0067
Echinococcus granulosus tyrosine protein kinase Src64B 0.0214 0.0723 0.071
Loa Loa (eye worm) haspin protein kinase 0.0228 0.0798 0.115
Echinococcus granulosus mitogen activated protein kinase 3 0.0198 0.064 0.0628
Entamoeba histolytica tyrosin kinase, putative 0.0094 0.008 0.0188
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Giardia lamblia Kinase, CDC7 0.0218 0.0748 0.2077
Schistosoma mansoni protein kinase 0.0094 0.008 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0071 0.0072
Trypanosoma cruzi heat shock protein 90, putative 0.057 0.2645 0.7392
Trichomonas vaginalis CAMK family protein kinase 0.0344 0.1425 0.3991
Trichomonas vaginalis heat shock protein, putative 0.0738 0.355 1
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0189 0.0588 0.0848
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0638 0.3011 0.434
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Onchocerca volvulus 0.0167 0.0472 0.0684
Trichomonas vaginalis heat shock protein, putative 0.057 0.2645 0.7441
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0105 0.0138 0.0168
Loa Loa (eye worm) hypothetical protein 0.0094 0.008 0.0115
Brugia malayi Protein kinase domain containing protein 0.0172 0.05 0.0703
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.057 0.2645 0.2635
Schistosoma mansoni eukaryotic elongation factor 2 kinase (eef-2 kinase) 0.0106 0.0141 0.0157
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0094 0.008 0.0082
Echinococcus granulosus cyclin dependent kinase 0.0172 0.05 0.0487
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0214 0.0723 0.0877
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0198 0.064 0.1615
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0168 0.0476 0.1142
Leishmania major heat shock protein, putative 0.0293 0.1153 0.3092
Brugia malayi serine/threonine-protein kinase 6 0.0403 0.1744 0.2499
Plasmodium vivax glycogen synthase kinase 3, putative 0.0189 0.0588 0.1465
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Leishmania major developmentally regulated phosphoprotein-like protein 0.0542 0.2495 0.696
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0168 0.0476 0.0691
Echinococcus granulosus natriuretic peptide receptor 1 0.0094 0.008 0.0067
Loa Loa (eye worm) hypothetical protein 0.0476 0.2136 0.3079
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Echinococcus multilocularis natriuretic peptide receptor 1 0.0094 0.008 0.0082
Echinococcus granulosus tyrosine protein kinase Fyn 0.0214 0.0723 0.071
Trypanosoma cruzi cdc2-related kinase 1 0.0172 0.05 0.1211
Trichomonas vaginalis CAMK family protein kinase 0.0302 0.1201 0.3357
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0933 0.26
Trypanosoma cruzi heat shock protein, putative 0.0293 0.1153 0.3092
Echinococcus granulosus casein kinase ii subunit beta 0.0122 0.0229 0.0216
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Giardia lamblia Kinase, NEK 0.0094 0.008 0.0188
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0094 0.008 0.0067
Echinococcus granulosus cyclin B 0.0106 0.0145 0.0132
Brugia malayi Tyrosine-protein kinase PR2 0.0094 0.008 0.0096
Schistosoma mansoni pyruvate dehydrogenase 0.0542 0.2495 0.3068
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0093 0.0071 0.0058
Brugia malayi hypothetical protein 0.0094 0.0077 0.0092
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Loa Loa (eye worm) hypothetical protein 0.0168 0.0476 0.0686
Schistosoma mansoni hypothetical protein 0.0135 0.0299 0.0353
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Trypanosoma cruzi cyclin, putative 0.0106 0.0145 0.0187
Plasmodium vivax DNA topoisomerase II, putative 0.0168 0.0476 0.1142
Entamoeba histolytica protein kinase, putative 0.0168 0.0476 0.1309
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0094 0.008 0.0188
Trichomonas vaginalis CMGC family protein kinase 0.0189 0.0588 0.1625
Loa Loa (eye worm) STE/STE20/YSK protein kinase 0.0368 0.1556 0.2242
Brugia malayi P38 map kinase family protein 2 0.0448 0.1988 0.2851
Onchocerca volvulus 0.0218 0.0748 0.1162
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Schistosoma mansoni nck2/grb4 0.0119 0.0214 0.0248
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Entamoeba histolytica hypothetical protein 0.0095 0.0082 0.0194
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0168 0.0476 0.0572
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.05 0.1376
Loa Loa (eye worm) hypothetical protein 0.0152 0.0388 0.0559
Loa Loa (eye worm) TK/FER protein kinase 0.0167 0.0472 0.068
Brugia malayi serine/threonine protein kinase 6 0.0403 0.1744 0.2499
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0165 0.0461 0.0449
Plasmodium falciparum casein kinase II beta chain 0.0122 0.0229 0.043
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Brugia malayi SH2 domain containing protein 0.0167 0.0472 0.0663
Brugia malayi Furin-like cysteine rich region family protein 0.0978 0.4847 0.6981
Echinococcus multilocularis protein kinase shaggy 0.0189 0.0588 0.0711
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.05 0.1376
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0189 0.0588 0.1465
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Entamoeba histolytica hypothetical protein 0.0095 0.0082 0.0194
Echinococcus granulosus CDC7 cell division cycle 7 0.0218 0.0748 0.0736
Echinococcus granulosus N chimaerin 0.0093 0.0072 0.0059
Giardia lamblia Kinase, AGC PKA 0.0098 0.0101 0.0249
Loa Loa (eye worm) hypothetical protein 0.069 0.3291 0.4744
Echinococcus granulosus tyrosine protein kinase Fyn 0.0214 0.0723 0.071
Loa Loa (eye worm) TK/FER protein kinase 0.0167 0.0472 0.068
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0461 0.0554
Echinococcus granulosus serine:threonine protein kinase haspin 0.0228 0.0798 0.0786
Onchocerca volvulus 0.0167 0.0472 0.0684
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0933 0.26
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0119 0.0214 0.0308
Entamoeba histolytica serine/threonine kinase, putative 0.0094 0.008 0.0188
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0172 0.05 0.0721
Leishmania major hypothetical protein, conserved 0.0168 0.0476 0.1142
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0165 0.0461 0.0554
Toxoplasma gondii AGC kinase 0.0161 0.0439 0.1036
Trichomonas vaginalis cyclins, putative 0.0106 0.0145 0.0372
Echinococcus multilocularis tyrosine protein kinase Abl 0.0476 0.214 0.2629
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0122 0.0229 0.0263
Plasmodium falciparum DNA topoisomerase 2 0.0168 0.0476 0.1142
Trypanosoma cruzi DNA topoisomerase II, putative 0.0168 0.0476 0.1142
Brugia malayi kinase, mitochondrial precursor 0.0542 0.2495 0.3585
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0586 0.2732 0.3937
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Leishmania major mitochondrial DNA topoisomerase II 0.0168 0.0476 0.1142
Loa Loa (eye worm) hypothetical protein 0.0168 0.0476 0.0686
Schistosoma mansoni cell adhesion molecule 0.0237 0.0849 0.1033
Echinococcus multilocularis heat shock protein 0.0738 0.355 0.4372
Brugia malayi hypothetical protein 0.0094 0.008 0.0096
Echinococcus multilocularis cyclin dependent kinase 0.0172 0.05 0.0602
Brugia malayi Tyrosine-protein kinase abl-1 0.0424 0.186 0.2667
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Entamoeba histolytica protein kinase, putative 0.0089 0.005 0.0104
Toxoplasma gondii CMGC kinase, CK2 family 0.0253 0.0933 0.2458
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0094 0.008 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Echinococcus granulosus defective proboscis extension response 0.0204 0.0672 0.0659
Brugia malayi Protein kinase domain containing protein 0.0645 0.3047 0.4381
Echinococcus multilocularis tyrosine protein kinase shark 0.1582 0.8103 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0094 0.008 0.0082
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0094 0.008 0.0082
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0095 0.0082 0.0194
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Loa Loa (eye worm) hypothetical protein 0.0106 0.0145 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0611 0.0739
Brugia malayi Serine/threonine-protein kinase Pim-3 0.056 0.2589 0.3719
Trypanosoma brucei aurora B kinase 0.0403 0.1744 0.4795
Loa Loa (eye worm) TK/DDR protein kinase 0.0094 0.008 0.0115
Echinococcus granulosus serine threonine protein kinase 0.0368 0.1556 0.1544
Schistosoma mansoni growth factor receptor-bound protein 0.0125 0.0242 0.0283
Loa Loa (eye worm) TK/ACK protein kinase 0.0094 0.008 0.0115
Entamoeba histolytica hypothetical protein 0.0094 0.008 0.0188
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0094 0.008 0.0082
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Brugia malayi Protein kinase c protein 2 0.0186 0.0573 0.0808
Schistosoma mansoni protein kinase 0.0124 0.0242 0.0283
Trypanosoma brucei polo-like protein kinase 0.0344 0.1425 0.3876
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0172 0.05 0.0721
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.008 0.0082
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0748 0.3607 0.3599
Schistosoma mansoni serine/threonine-protein kinase 0.0105 0.0138 0.0154
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0476 0.1309
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0542 0.2495 0.696
Brugia malayi Protein kinase domain containing protein 0.0167 0.0472 0.0663
Schistosoma mansoni serine/threonine protein kinase 0.0629 0.2961 0.3643
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0168 0.0476 0.1142
Onchocerca volvulus 0.0094 0.008 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.1021 0.2849
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0476 0.1309
Echinococcus multilocularis 0.0268 0.1015 0.1239
Echinococcus multilocularis c src tyrosine kinase 0.0214 0.0723 0.0877
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0214 0.0723 0.0877
Echinococcus granulosus mitogen activated protein kinase 11 0.0448 0.1988 0.1977
Loa Loa (eye worm) hypothetical protein 0.0357 0.1497 0.2158
Echinococcus granulosus kinase suppressor of Ras 1 0.0094 0.008 0.0067
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Loa Loa (eye worm) TK protein kinase 0.0094 0.008 0.0115
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Trichomonas vaginalis endoplasmin, putative 0.0461 0.2058 0.5781
Brugia malayi cell division control protein 2 homolog 0.0172 0.05 0.0703
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Brugia malayi hypothetical protein 0.0167 0.0472 0.0663
Echinococcus multilocularis protein KINase family member (kin 25) 0.0306 0.1222 0.1494
Schistosoma mansoni hypothetical protein 0.0135 0.0299 0.0353
Trypanosoma brucei heat shock protein, putative 0.0738 0.355 1
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.1021 0.2849
Schistosoma mansoni tyrosine kinase 0.0214 0.0723 0.0877
Echinococcus granulosus mitogen activated protein kinase 0.0198 0.064 0.0628
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0167 0.0472 0.0459
Loa Loa (eye worm) TK/ALK protein kinase 0.0878 0.4306 0.6207
Echinococcus granulosus activin receptor type 0.0124 0.0242 0.0229
Trichomonas vaginalis CMGC family protein kinase 0.0189 0.0588 0.1625
Loa Loa (eye worm) TK/FER protein kinase 0.0167 0.0472 0.068
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0124 0.0242 0.0467
Loa Loa (eye worm) hypothetical protein 0.0094 0.008 0.0115
Brugia malayi Hr1 repeat family protein 0.0093 0.0071 0.0084
Brugia malayi MHCK/EF2 kinase domain family protein 0.0106 0.0141 0.0184
Echinococcus granulosus serine:threonine protein kinase N2 0.0093 0.0071 0.0058
Brugia malayi heat shock protein 90 0.0738 0.355 0.5108
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0168 0.0476 0.0668
Trypanosoma cruzi polo-like protein kinase, putative 0.0344 0.1425 0.3876
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0228 0.0798 0.097
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0093 0.0071 0.0072
Plasmodium vivax serine/threonine-specific protein kinase, putative 0.0368 0.1556 0.4252
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0198 0.064 0.1615
Brugia malayi Protein kinase domain containing protein 0.1116 0.5589 0.8053
Plasmodium vivax casein kinase II beta chain, putative 0.0122 0.0229 0.043
Entamoeba histolytica hypothetical protein 0.0094 0.008 0.0188
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0542 0.2495 0.3068
Brugia malayi Kinase associated domain 1 family protein 0.0135 0.0299 0.0413
Schistosoma mansoni hypothetical protein 0.0228 0.0798 0.097
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Echinococcus granulosus protein kinase c iota type 0.0113 0.018 0.0167
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Trypanosoma brucei heat shock protein 84, putative 0.0293 0.1153 0.3092
Echinococcus multilocularis raf serine:threonine protein kinase 0.0115 0.0188 0.0217
Trypanosoma cruzi heat shock protein 85, putative 0.057 0.2645 0.7392
Echinococcus granulosus endoplasmin 0.057 0.2645 0.2635
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.064 0.1773
Loa Loa (eye worm) AUR protein kinase 0.0403 0.1744 0.2513
Schistosoma mansoni tyrosine kinase 0.0782 0.3786 0.4664
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1116 0.5589 0.6893
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0172 0.05 0.0721
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.008 0.0082
Echinococcus granulosus activated cdc42 kinase 1 0.0645 0.3047 0.3037
Brugia malayi Tyrosine-protein kinase abl-1 0.0476 0.214 0.3071
Brugia malayi Serine/threonine-protein kinase Nek7 0.0717 0.3437 0.4944
Schistosoma mansoni pyruvate dehydrogenase 0.0374 0.159 0.1949
Entamoeba histolytica hypothetical protein 0.0094 0.008 0.0188
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0302 0.1201 0.1468
Echinococcus granulosus tyrosine protein kinase HCK 0.0094 0.008 0.0067
Trichomonas vaginalis AGC family protein kinase 0.0094 0.008 0.0188
Trypanosoma cruzi myosin heavy chain kinase A, putative 0.0106 0.0141 0.0175
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0094 0.008 0.0115
Brugia malayi Endoplasmin precursor 0.0738 0.355 0.5108
Schistosoma mansoni growth factor receptor-bound protein 0.0119 0.0214 0.0248
Brugia malayi Protein kinase domain containing protein 0.0657 0.3115 0.448
Schistosoma mansoni endoplasmin 0.0738 0.355 0.4372
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Entamoeba histolytica hypothetical protein 0.0094 0.008 0.0188
Loa Loa (eye worm) TK/FER protein kinase 0.0167 0.0472 0.068
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Loa Loa (eye worm) hypothetical protein 0.0204 0.0672 0.0968
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0293 0.1153 0.3222
Brugia malayi SH2 domain containing protein 0.0167 0.0472 0.0663
Brugia malayi Hsp90 protein 0.0293 0.1153 0.1646
Schistosoma mansoni tyrosine kinase 0.0214 0.0723 0.0877
Trichomonas vaginalis TK family protein kinase 0.0098 0.01 0.0247
Plasmodium vivax endoplasmin, putative 0.0738 0.355 1
Leishmania major casein kinase II, putative 0.0253 0.0933 0.2458
Loa Loa (eye worm) CDC7 protein kinase 0.0218 0.0748 0.1078
Echinococcus multilocularis ephrin type A receptor 4 A 0.0094 0.008 0.0082
Brugia malayi Protein kinase domain containing protein 0.0878 0.4308 0.6202
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Schistosoma mansoni pyruvate dehydrogenase 0.0374 0.159 0.1949
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Onchocerca volvulus 0.0094 0.008 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.056 0.2589 0.3184
Plasmodium vivax casein kinase II beta chain, putative 0.0122 0.0229 0.043
Loa Loa (eye worm) AGC/PKN protein kinase 0.0093 0.0071 0.0103
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0117 0.0202 0.0292
Loa Loa (eye worm) hypothetical protein 0.0142 0.0338 0.0487
Plasmodium vivax DNA gyrase subunit B, putative 0.0168 0.0476 0.1142
Echinococcus multilocularis Immunoglobulin 0.0204 0.0672 0.0814
Trichomonas vaginalis CAMK family protein kinase 0.0344 0.1425 0.3991
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0302 0.1201 0.1189
Mycobacterium ulcerans heat shock protein 90 0.057 0.2645 1
Trichomonas vaginalis cyclin B, putative 0.0106 0.0145 0.0372
Schistosoma mansoni tyrosine kinase 0.1582 0.8103 1
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Echinococcus multilocularis aurora kinase A 0.0403 0.1744 0.2139
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0093 0.0072 0.0072
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Echinococcus multilocularis calcium activated potassium channel 0.0165 0.0461 0.0554
Echinococcus granulosus protein kinase C gamma type 0.0228 0.0802 0.079
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0122 0.0229 0.043
Echinococcus granulosus tyrosine protein kinase csk 0.0094 0.008 0.0067
Brugia malayi protein kinase C II. 0.0117 0.0202 0.0273
Entamoeba histolytica hypothetical protein 0.0094 0.008 0.0188
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0084 0.0023 0.0033
Loa Loa (eye worm) serine/threonine protein kinase 0.0094 0.008 0.0115
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Loa Loa (eye worm) hypothetical protein 0.055 0.2538 0.3658
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0214 0.0723 0.071
Giardia lamblia Kinase, CMGC GSK 0.0189 0.0588 0.1625
Schistosoma mansoni tyrosine kinase 0.0214 0.0723 0.0877
Trichomonas vaginalis CAMK family protein kinase 0.0302 0.1201 0.3357
Trypanosoma brucei developmentally regulated phosphoprotein 0.0542 0.2495 0.696
Echinococcus multilocularis tyrosine protein kinase HCK 0.0094 0.008 0.0082
Schistosoma mansoni tyrosine kinase 0.0933 0.4602 0.5672
Echinococcus multilocularis N chimaerin 0.0093 0.0072 0.0072
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0166 0.0464 0.0669
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0748 0.2077
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.01 0.0108 0.0095
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0629 0.2961 0.2951
Schistosoma mansoni protein kinase 0.0094 0.008 0.0082
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0167 0.0472 0.1297
Trypanosoma brucei rac serine-threonine kinase, putative 0.0168 0.0476 0.1143
Schistosoma mansoni kinase 0.0189 0.059 0.0713
Trypanosoma brucei protein kinase, putative 0.0189 0.0588 0.1465
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0137 0.0349
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.01 0.0108 0.0118
Schistosoma mansoni casein kinase II beta subunit 0.0122 0.0229 0.0267
Echinococcus multilocularis cyclin dependent kinase 1 0.0172 0.05 0.0602
Echinococcus granulosus fibroblast growth factor receptor 4 0.0423 0.1851 0.184
Onchocerca volvulus 0.0094 0.008 0.0005
Trichomonas vaginalis protein tyrosine kinase, putative 0.0094 0.008 0.0188
Echinococcus granulosus twitchin 0.027 0.1026 0.1014
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.008 0.0188
Leishmania major protein kinase, putative 0.0124 0.0242 0.0467
Brugia malayi Protein kinase domain containing protein 0.0167 0.0472 0.0663
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0253 0.0933 0.2458
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0094 0.008 0.0082
Entamoeba histolytica cell division protein kinase 2, putative 0.0172 0.05 0.1376
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0293 0.1153 0.1409
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Schistosoma mansoni protein kinase 0.0253 0.0933 0.1137
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0122 0.0229 0.061
Echinococcus granulosus tyrosine protein kinase Src42A 0.0214 0.0723 0.071
Trichomonas vaginalis AGC family protein kinase 0.01 0.0108 0.0268
Schistosoma mansoni tyrosine kinase 0.1509 0.7711 0.9515
Toxoplasma gondii ck2 beta subunit 0.0122 0.0229 0.043
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Schistosoma mansoni protein kinase 0.0124 0.0242 0.0283
Echinococcus granulosus serine threonine protein kinase nrc 0.0098 0.0101 0.0088
Echinococcus granulosus tyrosine protein kinase csk 0.0094 0.008 0.0067
Loa Loa (eye worm) hypothetical protein 0.0212 0.0713 0.1028
Loa Loa (eye worm) TK protein kinase 0.0094 0.008 0.0115
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0093 0.0071 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0911 0.111
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0168 0.0476 0.1308
Entamoeba histolytica protein kinase, putative 0.0103 0.0125 0.0317
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Echinococcus granulosus receptor type guanylyl cyclase 0.0094 0.008 0.0067
Entamoeba histolytica cysteine surface protein, putative 0.0094 0.008 0.0188
Trypanosoma brucei Casein kinase II 0.0253 0.0933 0.2458
Echinococcus multilocularis serine:threonine protein kinase N2 0.0093 0.0071 0.0072
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0189 0.0588 0.0711
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.008 0.0188
Onchocerca volvulus 0.0094 0.008 0.0005
Echinococcus multilocularis protein kinase c epsilon type 0.0117 0.0202 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Brugia malayi Protein kinase domain containing protein 0.0168 0.0476 0.0669
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0748 0.2077
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0214 0.0723 0.0877
Trichomonas vaginalis STE family protein kinase 0.0094 0.008 0.0188
Echinococcus granulosus c src tyrosine kinase 0.0214 0.0723 0.071
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0188 0.0217
Leishmania major protein kinase, putative 0.0403 0.1744 0.4795
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0403 0.1744 0.2139
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0094 0.008 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0586 0.2732 0.336
Entamoeba histolytica ankyrin repeat protein 0.0094 0.008 0.0188
Trypanosoma brucei myosin heavy chain kinase A, putative 0.0106 0.0141 0.0175
Loa Loa (eye worm) hypothetical protein 0.0204 0.0672 0.0968
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.057 0.2645 1
Echinococcus granulosus tyrosine kinase 0.0094 0.008 0.0067
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0403 0.1744 0.1733
Echinococcus multilocularis tyrosine protein kinase pr2 0.0094 0.008 0.0082
Schistosoma mansoni protein kinase 0.0094 0.008 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0204 0.0672 0.0814
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0854 0.4179 0.5149
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0122 0.0229 0.061
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Entamoeba histolytica receptor protein kinase, putative 0.0094 0.008 0.0188
Entamoeba histolytica protein kinase , putative 0.0403 0.1744 0.4893
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.057 0.2645 0.7392
Entamoeba histolytica serine/threonine kinase, putative 0.0094 0.008 0.0188
Brugia malayi Immunoglobulin I-set domain containing protein 0.0458 0.2043 0.2932
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0093 0.0072 0.0059
Loa Loa (eye worm) TK/EPH protein kinase 0.0094 0.008 0.0115
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0189 0.0588 0.0576
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.01 0.0247
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0933 0.26
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0124 0.0242 0.0467
Entamoeba histolytica hypothetical protein 0.0094 0.008 0.0188
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0094 0.008 0.0096
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Entamoeba histolytica heat shock protein 90, putative 0.0738 0.355 1
Giardia lamblia Heat shock protein HSP 90-alpha 0.0738 0.355 1
Echinococcus multilocularis casein kinase ii subunit beta 0.0122 0.0229 0.0267
Brugia malayi Csnk2b protein 0.0122 0.0229 0.0312
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0933 0.26
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0911 0.111
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Trypanosoma cruzi heat shock protein 85, putative 0.0738 0.355 1
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0437 0.1929 0.278
Trichomonas vaginalis CAMK family protein kinase 0.0437 0.1929 0.5416
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0629 0.2961 0.4267
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0293 0.1153 0.1141
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Echinococcus multilocularis epidermal growth factor receptor 0.0748 0.3607 0.4443
Trypanosoma brucei cdc2-related kinase 3 0.0172 0.05 0.1211
Echinococcus granulosus epidermal growth factor receptor 0.0978 0.4847 0.4841
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0198 0.064 0.0923
Brugia malayi Immunoglobulin I-set domain containing protein 0.1366 0.6938 1
Loa Loa (eye worm) TK/FER protein kinase 0.0167 0.0472 0.068
Brugia malayi Protein kinase domain containing protein 0.0167 0.0472 0.0663
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0094 0.008 0.0082
Schistosoma mansoni tyrosine protein kinase 0.0094 0.008 0.0082
Leishmania major myosin heavy chain kinase a-like protein 0.0106 0.0141 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0202 0.0234
Brugia malayi Sex muscle abnormal protein 5 0.0119 0.0214 0.029
Entamoeba histolytica protein kinase, putative 0.0403 0.1744 0.4893
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0094 0.008 0.0082
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Trichomonas vaginalis AGC family protein kinase 0.0093 0.0071 0.0164
Echinococcus granulosus protein kinase shaggy 0.0189 0.0588 0.0576
Plasmodium falciparum heat shock protein 90, putative 0.0293 0.1153 0.3092
Echinococcus multilocularis protein kinase 0.0094 0.008 0.0082
Schistosoma mansoni tyrosine kinase 0.0654 0.3098 0.3814
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0168 0.0476 0.1142
Brugia malayi Protein kinase domain containing protein 0.057 0.2645 0.3801
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0214 0.0723 0.0877
Onchocerca volvulus 0.1035 0.5151 0.8786
Trichomonas vaginalis TKL family protein kinase 0.0098 0.01 0.0247
Loa Loa (eye worm) hypothetical protein 0.0094 0.008 0.0115
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Giardia lamblia Pms1-like protein 0.0168 0.0476 0.1308
Brugia malayi Raf kinase 0.0094 0.008 0.0096
Echinococcus granulosus eukaryotic elongation factor 2 kinase 0.0106 0.0141 0.0128
Echinococcus granulosus MAM 0.0094 0.0077 0.0064
Echinococcus granulosus Immunoglobulin 0.0204 0.0672 0.0659
Loa Loa (eye worm) TK/Met protein kinase 0.0094 0.008 0.0115
Leishmania major cyclin 0.0106 0.0145 0.0187
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0172 0.05 0.1211
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Trypanosoma brucei heat shock protein, putative 0.0738 0.355 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0093 0.0072 0.0072
Plasmodium falciparum protein kinase, putative 0.0368 0.1556 0.4252
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0122 0.0229 0.0263
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0098 0.0101 0.0109
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1116 0.5589 0.5584
Loa Loa (eye worm) endoplasmin 0.0738 0.355 0.5117
Trichomonas vaginalis AGC family protein kinase 0.0403 0.1744 0.4893
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Loa Loa (eye worm) TK protein kinase 0.0094 0.008 0.0115
Brugia malayi Guanylyl cyclase protein 23 0.0094 0.008 0.0096
Brugia malayi RhoGAP domain containing protein 0.0093 0.0072 0.0085
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Echinococcus multilocularis neuroglian 0.024 0.0864 0.1051
Onchocerca volvulus 0.0167 0.0472 0.0684
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.05 0.0602
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Giardia lamblia Casein kinase II beta chain 0.0122 0.0229 0.061
Entamoeba histolytica serine/threonine kinase, putative 0.0094 0.008 0.0188
Loa Loa (eye worm) NEK/NEK6 protein kinase 0.0717 0.3437 0.4954
Trichomonas vaginalis AGC family protein kinase 0.0403 0.1744 0.4893
Schistosoma mansoni endoplasmin 0.0738 0.355 0.4372
Brugia malayi Protein kinase domain containing protein 0.0167 0.0472 0.0663
Trichomonas vaginalis cyclin B, putative 0.0106 0.0145 0.0372
Echinococcus multilocularis heat shock protein 90 0.057 0.2645 0.3253
Loa Loa (eye worm) hypothetical protein 0.0106 0.0141 0.0203
Entamoeba histolytica protein kinase, putative 0.0095 0.0082 0.0194
Entamoeba histolytica protein kinase, putative 0.0368 0.1556 0.4361
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.4852 0.5981
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Echinococcus granulosus retinal guanylyl cyclase 2 0.0094 0.008 0.0067
Echinococcus granulosus tyrosine protein kinase csk 0.0094 0.008 0.0067
Entamoeba histolytica serine/threonine protein kinase, putative 0.0344 0.1425 0.3991
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0214 0.0723 0.0877
Loa Loa (eye worm) AGC/AKT protein kinase 0.0168 0.0476 0.0687
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0168 0.0476 0.1142
Schistosoma mansoni tyrosine kinase 0.1116 0.5589 0.6893
Echinococcus multilocularis receptor type guanylyl cyclase 0.0094 0.008 0.0082
Schistosoma mansoni protein kinase 0.0657 0.3115 0.3835
Giardia lamblia Kinase, CMGC CK2 0.0253 0.0933 0.26
Echinococcus granulosus integrin linked protein kinase 0.0094 0.008 0.0067
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.056 0.2589 0.4349
Trypanosoma cruzi heat shock protein 90, putative 0.0738 0.355 1
Onchocerca volvulus 0.0106 0.0145 0.0117
Trichomonas vaginalis DNA topoisomerase II, putative 0.0168 0.0476 0.1308
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0168 0.0476 0.1308
Schistosoma mansoni serine/threonine-protein kinase 0.0105 0.0138 0.0154
Loa Loa (eye worm) TK/FER protein kinase 0.0094 0.008 0.0115
Echinococcus multilocularis hypothetical protein 0.0135 0.0299 0.0353
Brugia malayi map kinase activated protein kinase protein 2 0.0629 0.2961 0.4257
Trichomonas vaginalis protein kinase atn1, putative 0.0094 0.008 0.0188
Trypanosoma brucei Heat shock protein 83, putative 0.0738 0.355 1
Onchocerca volvulus 0.0094 0.008 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0476 0.1309
Toxoplasma gondii DNA topoisomerase 2, putative 0.0168 0.0476 0.1142
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0094 0.008 0.0188
Brugia malayi ephrin receptor 1 precursor 0.0094 0.008 0.0096
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Echinococcus multilocularis growth factor receptor bound protein 2 0.0119 0.0214 0.0248
Onchocerca volvulus 0.0167 0.0472 0.0684
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0168 0.0476 0.1142
Toxoplasma gondii heat shock protein 90, putative 0.0738 0.355 1
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.05 0.0602
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0214 0.0723 0.0877
Trypanosoma cruzi cyclin, putative 0.0106 0.0145 0.0187
Giardia lamblia Kinase 0.0094 0.008 0.0188
Loa Loa (eye worm) TK protein kinase 0.0458 0.2043 0.2945
Brugia malayi p70 ribosomal S6 kinase beta 0.0161 0.0439 0.0616
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0094 0.008 0.0188
Plasmodium vivax protein kinase Crk2 0.0172 0.05 0.1211
Trypanosoma brucei heat shock protein 90, putative 0.0738 0.355 1
Brugia malayi protein-tyrosine kinase 0.0167 0.0472 0.0663
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Entamoeba histolytica tyrosin kinase, putative 0.0105 0.0137 0.0349
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Loa Loa (eye worm) hypothetical protein 0.0119 0.0214 0.0308
Trypanosoma brucei heat shock protein 90, putative 0.0738 0.355 1
Echinococcus multilocularis protein kinase c iota type 0.0113 0.018 0.0206
Trypanosoma brucei heat shock protein, putative 0.0738 0.355 1
Schistosoma mansoni tyrosine kinase 0.0214 0.0723 0.0877
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0344 0.1425 0.1413
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0586 0.2731 0.2721
Loa Loa (eye worm) TTK protein kinase 0.0269 0.1021 0.1472
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0167 0.0472 0.0567
Echinococcus multilocularis mitogen activated protein kinase 0.0198 0.064 0.0775
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0094 0.008 0.0115
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0094 0.008 0.0115
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0476 0.1309
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0168 0.0476 0.0691
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0189 0.0588 0.1465
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0094 0.008 0.0082
Entamoeba histolytica serine/threonine kinase, putative 0.0094 0.008 0.0188
Brugia malayi Fibronectin type III domain containing protein 0.0204 0.0672 0.0951
Trypanosoma cruzi aurora B kinase, putative 0.0403 0.1744 0.4795
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0094 0.008 0.0082
Loa Loa (eye worm) CAMK/PIM protein kinase 0.056 0.2589 0.3731
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0094 0.008 0.0082
Echinococcus granulosus cyclin dependent kinase 5 0.0172 0.05 0.0487
Echinococcus multilocularis tyrosine kinase 0.0167 0.0472 0.0567
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Echinococcus multilocularis roundabout 2 0.0273 0.1041 0.127
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0071 0.0072
Entamoeba histolytica PH domain containing protein kinase, putative 0.0105 0.0138 0.0353
Echinococcus granulosus heat shock protein 90 0.057 0.2645 0.2635
Plasmodium falciparum endoplasmin, putative 0.0461 0.2058 0.57
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0293 0.1153 0.1863
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0093 0.0072 0.0103
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0094 0.008 0.0096
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Plasmodium falciparum protein kinase 5 0.0172 0.05 0.1211
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0094 0.008 0.0005
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0094 0.008 0.0082
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0093 0.0071 0.0103
Schistosoma mansoni tyrosine kinase 0.0163 0.0449 0.0539
Entamoeba histolytica protein kinase, putative 0.0089 0.005 0.0104
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.013 0.0272 0.0259
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0124 0.0242 0.0467
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0172 0.05 0.0487
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0461 0.0554
Echinococcus granulosus tyrosine protein kinase Fyn 0.0214 0.0723 0.071
Echinococcus granulosus tyrosine protein kinase Srms 0.0167 0.0472 0.0459
Toxoplasma gondii heat shock protein HSP90 0.0738 0.355 1
Echinococcus multilocularis tyrosine protein kinase Blk 0.0167 0.0472 0.0567
Echinococcus granulosus NCK adaptor protein 0.0119 0.0214 0.0201
Giardia lamblia G2/mitotic-specific cyclin B 0.0106 0.0145 0.0372
Brugia malayi hypothetical protein 0.0204 0.0672 0.0951
Loa Loa (eye worm) TOPoisomerase family member 0.0168 0.0476 0.0686
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0214 0.0723 0.0877
Echinococcus multilocularis endoplasmin 0.057 0.2645 0.3253
Echinococcus granulosus tyrosine protein kinase Lyn 0.0244 0.0885 0.0873
Brugia malayi Protein kinase domain containing protein 0.0943 0.4656 0.6705
Entamoeba histolytica hypothetical protein, conserved 0.0094 0.008 0.0188
Trichomonas vaginalis AGC family protein kinase 0.0403 0.1744 0.4893
Plasmodium vivax heat shock protein, putative 0.0293 0.1153 0.3092
Echinococcus multilocularis protein kinase 0.0094 0.008 0.0082
Echinococcus granulosus insulin receptor 0.1116 0.5589 0.5584
Entamoeba histolytica hypothetical protein 0.0094 0.008 0.0188
Plasmodium falciparum protein kinase, putative 0.0124 0.0242 0.0467
Echinococcus multilocularis eukaryotic elongation factor 2 kinase 0.0106 0.0141 0.0157
Schistosoma mansoni protein kinase 0.0094 0.008 0.0082
Trypanosoma cruzi CYC2-like cyclin, putative 0.0106 0.0145 0.0187
Schistosoma mansoni serine/threonine protein kinase 0.0368 0.1556 0.1907
Trypanosoma cruzi cdc2-related kinase 1 0.0172 0.05 0.1211
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0933 0.26
Brugia malayi Protein kinase domain containing protein 0.0437 0.1929 0.2766
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0476 0.1309
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Echinococcus multilocularis rac serine:threonine kinase 0.0105 0.0138 0.0154
Echinococcus granulosus Protein kinase C brain isozyme 0.0248 0.0911 0.0899
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0448 0.1988 0.5497
Echinococcus multilocularis tyrosine protein kinase 0.0094 0.008 0.0082
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0094 0.008 0.0082
Trichomonas vaginalis cyclin A, putative 0.0106 0.0145 0.0372
Echinococcus granulosus aurora kinase A 0.0403 0.1744 0.1733
Brugia malayi C-terminal src kinase protein 1 0.0094 0.008 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.064 0.0775
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0344 0.1425 0.2054
Loa Loa (eye worm) TK protein kinase 0.0094 0.008 0.0115
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0103 0.0125 0.0317
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0094 0.008 0.0005
Brugia malayi Variant SH3 domain containing protein 0.0119 0.0214 0.029
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Onchocerca volvulus Dual specificity protein kinase TTK homolog 0.0269 0.1021 0.1634
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0198 0.064 0.1615
Loa Loa (eye worm) heat shock protein 75 0.0293 0.1153 0.1661
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0306 0.1224 0.3296
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.05 0.1376
Trypanosoma brucei myosin heavy chain kinase A, putative 0.0106 0.0141 0.0175
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0122 0.0229 0.043
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0094 0.008 0.0067
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Schistosoma mansoni serine/threonine kinase 0.0093 0.0071 0.0072
Brugia malayi serine/threonine-protein kinase PAK 7 0.0638 0.3011 0.4329
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Loa Loa (eye worm) TK/CSK protein kinase 0.0094 0.008 0.0115
Loa Loa (eye worm) TK/FER protein kinase 0.0167 0.0472 0.068
Brugia malayi hypothetical protein 0.0228 0.0798 0.1133
Echinococcus multilocularis tyrosine protein kinase csk 0.0094 0.008 0.0082
Entamoeba histolytica protein kinase domain containing protein 0.0124 0.0242 0.0646
Brugia malayi intracellular kinase 0.0189 0.0588 0.083
Loa Loa (eye worm) hypothetical protein 0.0094 0.008 0.0115
Loa Loa (eye worm) TK/FER protein kinase 0.0167 0.0472 0.068
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0228 0.0798 0.097
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0748 0.2077
Echinococcus multilocularis mitogen activated protein kinase 3 0.0198 0.064 0.0775
Loa Loa (eye worm) hypothetical protein 0.0094 0.0077 0.0111
Trichomonas vaginalis cyclin B, putative 0.0106 0.0145 0.0372
Entamoeba histolytica protein kinase, putative 0.0161 0.0439 0.1205
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Brugia malayi Variant SH3 domain containing protein 0.0084 0.0023 0.0014
Schistosoma mansoni tyrosine kinase 0.0748 0.3607 0.4443
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.013 0.0272 0.032
Entamoeba histolytica PH domain containing protein kinase, putative 0.0105 0.0138 0.0353
Schistosoma mansoni atypical protein kinase C 0.0113 0.018 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.008 0.0188
Echinococcus granulosus raf serine:threonine protein kinase 0.0115 0.0188 0.0175
Trypanosoma cruzi myosin heavy chain kinase A, putative 0.0106 0.0141 0.0175
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Entamoeba histolytica protein kinase, putative 0.0093 0.0071 0.0164
Echinococcus granulosus tyrosine kinase 0.0167 0.0472 0.0459
Loa Loa (eye worm) TK/FER protein kinase 0.0094 0.008 0.0115
Plasmodium falciparum heat shock protein 90, putative 0.0293 0.1153 0.3092
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0461 0.0554
Trypanosoma brucei protein kinase, putative 0.0238 0.0852 0.2226
Schistosoma mansoni serine/threonine kinase 0.0477 0.2141 0.263
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Brugia malayi integrin-linked kinase 0.0094 0.008 0.0096
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0423 0.1851 0.2272
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0139 0.0318 0.0688
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0094 0.008 0.0082
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0933 0.26
Entamoeba histolytica protein kinase domain containing protein 0.0253 0.0933 0.26
Loa Loa (eye worm) hypothetical protein 0.0094 0.008 0.0115
Trypanosoma cruzi DNA topoisomerase II, putative 0.0168 0.0476 0.1142
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0071 0.0072
Trypanosoma cruzi cdc2-related kinase 3 0.0172 0.05 0.1211
Loa Loa (eye worm) TK/FER protein kinase 0.0094 0.008 0.0115
Echinococcus multilocularis activin receptor type 0.0124 0.0242 0.0283
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Giardia lamblia Kinase, PLK 0.0344 0.1425 0.3991
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0094 0.008 0.0096
Echinococcus multilocularis Immunoglobulin 0.0204 0.0672 0.0814
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0461 0.0554
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Brugia malayi Protein kinase domain containing protein 0.0269 0.1021 0.1455
Brugia malayi Variant SH3 domain containing protein 0.0093 0.0072 0.0085
Echinococcus multilocularis CDC7 cell division cycle 7 0.0218 0.0748 0.0908
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0161 0.0439 0.0633
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0214 0.0723 0.071
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0461 0.0554
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0093 0.0071 0.0103
Brugia malayi SRC-1 0.0214 0.0723 0.1025
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0098 0.0101 0.0062
Echinococcus multilocularis activated cdc42 kinase 1 0.0645 0.3047 0.375
Trypanosoma brucei mitotic cyclin 6 0.0106 0.0145 0.0187
Trichomonas vaginalis CAMK family protein kinase 0.0185 0.0568 0.1568
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Loa Loa (eye worm) haspin protein kinase 0.0258 0.096 0.1384
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0168 0.0476 0.1142
Schistosoma mansoni heat shock protein 0.0293 0.1153 0.1409
Echinococcus multilocularis kinase suppressor of Ras 1 0.0094 0.008 0.0082
Loa Loa (eye worm) RGC/RGC protein kinase 0.0094 0.008 0.0115
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0167 0.0472 0.0567
Chlamydia trachomatis serine/threonine protein kinase 0.0717 0.3437 1
Echinococcus granulosus protein tyrosine kinase 0.0933 0.4602 0.4595
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0093 0.0071 0.0058
Schistosoma mansoni protein tyrosine kinase 0.0094 0.008 0.0082
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Loa Loa (eye worm) hypothetical protein 0.0094 0.0077 0.0111
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0094 0.008 0.0115
Giardia lamblia Kinase, CMGC GSK 0.0189 0.0588 0.1625
Loa Loa (eye worm) hypothetical protein 0.0273 0.1041 0.15
Brugia malayi Protein kinase domain containing protein 0.0167 0.0472 0.0663
Echinococcus multilocularis NCK adaptor protein 0.0125 0.0242 0.0283
Brugia malayi Protein kinase domain containing protein 0.0093 0.0071 0.0084
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Onchocerca volvulus 0.0218 0.0748 0.1162
Loa Loa (eye worm) TK/FER protein kinase 0.0167 0.0472 0.068
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.0748 0.0908
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0094 0.008 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.01 0.0247
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Loa Loa (eye worm) TK protein kinase 0.0094 0.008 0.0115
Plasmodium vivax heat shock protein 90, putative 0.0293 0.1153 0.3092
Loa Loa (eye worm) TK/FER protein kinase 0.0094 0.008 0.0115
Leishmania major DNA topoisomerase ii 0.0168 0.0476 0.1142
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0119 0.0214 0.0248
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0106 0.0145 0.0187
Onchocerca volvulus Serine\/threonine kinase homolog 0.0344 0.1425 0.2334
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0093 0.0071 0.0072
Giardia lamblia Protein 21.1 0.0094 0.008 0.0188
Echinococcus granulosus roundabout 2 0.0273 0.1041 0.1029
Loa Loa (eye worm) hypothetical protein 0.0645 0.3047 0.4391
Entamoeba histolytica protein kinase domain containing protein 0.0189 0.0588 0.1625
Plasmodium falciparum serine/threonine protein kinase, putative 0.0403 0.1744 0.4795
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0071 0.0072
Echinococcus multilocularis transfer RNA-Thr 0.0645 0.3047 0.375
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Echinococcus multilocularis integrin linked protein kinase 0.0094 0.008 0.0082
Schistosoma mansoni ephrin receptor 0.0094 0.008 0.0082
Schistosoma mansoni protein kinase 0.0094 0.008 0.0082
Schistosoma mansoni dual specificity serine/threonine tyrosine kinase 0.0269 0.1021 0.1246
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Loa Loa (eye worm) TK/EGFR protein kinase 0.0978 0.4847 0.6987
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0448 0.1988 0.2865
Entamoeba histolytica p21-activated kinase 0.0089 0.005 0.0104
Entamoeba histolytica protein kinase 2, putative 0.0098 0.0101 0.0249
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0248 0.0911 0.111
Loa Loa (eye worm) hypothetical protein 0.0131 0.0279 0.0403
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0122 0.0229 0.043
Schistosoma mansoni vesicular amine transporter 0.0204 0.0672 0.0814
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1366 0.6938 1
Echinococcus granulosus serine/threonine protein kinase 0.0105 0.0138 0.0125
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.056 0.2589 0.3184
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0237 0.0849 0.0837
Trichomonas vaginalis CAMK family protein kinase 0.0344 0.1425 0.3991
Brugia malayi Cyclin, N-terminal domain containing protein 0.0106 0.0145 0.019
Loa Loa (eye worm) hypothetical protein 0.0204 0.0672 0.0968
Leishmania major heat shock protein 83-1 0.0738 0.355 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0214 0.0723 0.0877
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0172 0.05 0.1211
Echinococcus granulosus protein kinase c epsilon type 0.0117 0.0202 0.0189
Entamoeba histolytica protein kinase, putative 0.0094 0.008 0.0188
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Loa Loa (eye worm) hypothetical protein 0.0306 0.1222 0.1761
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0344 0.1425 0.3876
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0214 0.0723 0.0877
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0131 0.0279 0.0329
Brugia malayi Protein kinase domain containing protein 0.0094 0.008 0.0096
Loa Loa (eye worm) TK/ROR protein kinase 0.013 0.0272 0.0392
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0448 0.1988 0.5497
Brugia malayi GSG2 0.0228 0.0798 0.1133
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0423 0.1851 0.184
Schistosoma mansoni cyclin B 0.0106 0.0145 0.0162
Echinococcus multilocularis mitogen activated protein kinase 14 0.0448 0.1988 0.2441
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0168 0.0476 0.1142
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0098 0.0101 0.0088
Echinococcus granulosus calcium activated potassium channel 0.0165 0.0461 0.0449
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Echinococcus multilocularis cyclin B 0.0106 0.0145 0.0162
Echinococcus granulosus casein kinase ii subunit alpha 0.0253 0.0933 0.0921
Loa Loa (eye worm) hypothetical protein 0.0237 0.0849 0.1223
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Brugia malayi hypothetical protein 0.0094 0.008 0.0096
Treponema pallidum heat shock protein 90 0.057 0.2645 1
Trichomonas vaginalis STE family protein kinase 0.0368 0.1556 0.4361
Onchocerca volvulus Tyrosine kinase homolog 0.1165 0.5852 1
Plasmodium falciparum casein kinase II beta chain 0.0122 0.0229 0.043
Plasmodium falciparum casein kinase 2, alpha subunit 0.0253 0.0933 0.2458
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0629 0.2961 0.3643
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Echinococcus multilocularis RNA directed DNA polymerase 0.0131 0.0279 0.0329
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0214 0.0723 0.0877
Trypanosoma cruzi heat shock protein 85, putative 0.0738 0.355 1
Brugia malayi Protein kinase domain containing protein 0.056 0.2589 0.3719
Loa Loa (eye worm) SRC-1 0.0214 0.0723 0.1042
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0094 0.008 0.0115
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Loa Loa (eye worm) Csnk2b protein 0.0122 0.0229 0.033
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0139 0.0318 0.0688
Entamoeba histolytica protein kinase domain containing protein 0.0094 0.008 0.0188
Entamoeba histolytica protein kinase, putative 0.0168 0.0476 0.1309
Loa Loa (eye worm) TK/FER protein kinase 0.0094 0.008 0.0115
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0189 0.0588 0.0848
Entamoeba histolytica hypothetical protein 0.0094 0.008 0.0188
Echinococcus multilocularis FL cytokine receptor 0.0094 0.008 0.0082
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Trichomonas vaginalis CAMK family protein kinase 0.0383 0.1637 0.459
Onchocerca volvulus 0.0167 0.0472 0.0684
Toxoplasma gondii Hsp90 domain-containing protein 0.0293 0.1153 0.3092
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0423 0.1851 0.2272
Plasmodium falciparum heat shock protein 90 0.0738 0.355 1
Brugia malayi bone morphogenetic protein type 1 receptor 0.0094 0.008 0.0096
Schistosoma mansoni tyrosine kinase 0.0654 0.3098 0.3814
Trypanosoma brucei protein kinase, putative 0.0124 0.0242 0.0467
Trichomonas vaginalis cyclins, putative 0.0106 0.0145 0.0372
Giardia lamblia Kinase, CMGC CDK 0.0172 0.05 0.1376
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.057 0.2645 1
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Loa Loa (eye worm) AUR protein kinase 0.0403 0.1744 0.2513
Echinococcus granulosus tyrosine protein kinase Blk 0.0167 0.0472 0.0459
Schistosoma mansoni DNA topoisomerase II 0.0168 0.0476 0.0572
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Schistosoma mansoni protein kinase 0.0094 0.008 0.0082
Entamoeba histolytica tyrosine kinase, putative 0.0094 0.008 0.0188
Echinococcus multilocularis serine threonine protein kinase 0.0228 0.0802 0.0975
Loa Loa (eye worm) TK/FER protein kinase 0.0094 0.008 0.0115
Plasmodium falciparum DNA gyrase subunit B 0.0168 0.0476 0.1142
Brugia malayi Protein kinase domain containing protein 0.0093 0.0071 0.0084
Schistosoma mansoni tyrosine kinase 0.0094 0.008 0.0082
Onchocerca volvulus 0.0167 0.0472 0.0684
Schistosoma mansoni adapter molecule crk 0.0119 0.0214 0.0248
Schistosoma mansoni tyrosine kinase 0.0978 0.4847 0.5976
Schistosoma mansoni serine/threonine RGC 0.0094 0.008 0.0082
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.057 0.2645 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0168 0.0476 0.1142
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Loa Loa (eye worm) CAMK/PIM protein kinase 0.056 0.2589 0.3731
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0094 0.008 0.0188
Onchocerca volvulus 0.0094 0.008 0.0005
Loa Loa (eye worm) TK/RYK protein kinase 0.0094 0.008 0.0115
Echinococcus granulosus retinal guanylyl cyclase 2 0.0094 0.008 0.0067
Loa Loa (eye worm) haspin protein kinase 0.0228 0.0798 0.115
Trichomonas vaginalis TKL family protein kinase 0.0094 0.008 0.0188
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0139 0.0318 0.0688
Echinococcus multilocularis dual specificity serine:threonine tyrosine 0.0269 0.1021 0.1246
Echinococcus granulosus tyrosine protein kinase shark 0.1582 0.8103 0.8101
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0168 0.0476 0.0463
Echinococcus granulosus tyrosine kinase 0.0167 0.0472 0.0459
Schistosoma mansoni serine/threonine protein kinase 0.0344 0.1425 0.1745
Trichomonas vaginalis casein kinase II beta chain, putative 0.0122 0.0229 0.061
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0189 0.0588 0.1465
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0448 0.1988 0.5497

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 5.0119 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.5774 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 44.6684 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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