Detailed information for compound 1487483

Basic information

Technical information
  • TDR Targets ID: 1487483
  • Name: N-(3-chloro-4-fluorophenyl)-N-[2-(cyclohexyla mino)-2-oxoethyl]thiadiazole-4-carboxamide
  • MW: 396.867 | Formula: C17H18ClFN4O2S
  • H donors: 1 H acceptors: 4 LogP: 3.68 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(CN(C(=O)c1csnn1)c1ccc(c(c1)Cl)F)NC1CCCCC1
  • InChi: 1S/C17H18ClFN4O2S/c18-13-8-12(6-7-14(13)19)23(17(25)15-10-26-22-21-15)9-16(24)20-11-4-2-1-3-5-11/h6-8,10-11H,1-5,9H2,(H,20,24)
  • InChiKey: AIUHPDHBUGQMJB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-chloro-4-fluoro-phenyl)-N-[2-(cyclohexylamino)-2-oxo-ethyl]thiadiazole-4-carboxamide
  • N-(3-chloro-4-fluorophenyl)-N-[2-(cyclohexylamino)-2-oxoethyl]-4-thiadiazolecarboxamide
  • N-(3-chloro-4-fluoro-phenyl)-N-[2-(cyclohexylamino)-2-keto-ethyl]thiadiazole-4-carboxamide
  • N-(3-chloro-4-fluoro-phenyl)-N-[2-(cyclohexylamino)-2-oxo-ethyl]-1,2,3-thiadiazole-4-carboxamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0398 0.0686
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0054 0.0546 0.1326
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.0546 0.2765
Brugia malayi hypothetical protein 0.0014 0.0033 0.0114
Echinococcus granulosus neuropeptide receptor 0.0014 0.0033 0.0039
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0014 0.0033 0.0033
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0129 0.1502 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0398 0.1367
Leishmania major cysteine peptidase A (CPA) 0.0054 0.0546 0.2765
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.0546 0.2765
Onchocerca volvulus 0.0014 0.0033 0.0021
Leishmania major cathepsin L-like protease 0.0054 0.0546 0.2765
Brugia malayi putative neuropeptide receptor NPR1 0.0014 0.0033 0.0114
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0297 0.4597
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0289 0.4454
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0289 0.0816
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0033 0.0033
Schistosoma mansoni adenoreceptor 0.0014 0.0033 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.0546 0.2765
Schistosoma mansoni cpg binding protein 0.003 0.0231 0.0272
Schistosoma mansoni biogenic amine (5HT) receptor 0.0014 0.0033 0.0039
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0014 0.0033 0.0033
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0398 0.0947
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0014 0.0033 0.0114
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0094
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0027 0.0032
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0053 0.0524 0.1798
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0259 0.3947
Entamoeba histolytica hypothetical protein 0.0043 0.0407 0.0969
Trichomonas vaginalis esterase, putative 0.0043 0.0398 0.0947
Echinococcus multilocularis neuropeptide Y receptor 0.0014 0.0033 0.0033
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0054 0.0546 0.0546
Echinococcus multilocularis GPCR, family 2 0.0048 0.0465 0.0465
Plasmodium falciparum serine repeat antigen 5 0.0014 0.0027 0.0387
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.0546 0.2765
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0014 0.0033 0.0039
Echinococcus multilocularis orexin receptor type 2 0.0014 0.0033 0.0033
Brugia malayi cathepsin L precursor 0.0014 0.0027 0.0094
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0026 0.0181 0.0809
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0014 0.0033 0.0039
Schistosoma mansoni opsin-like receptor 0.0014 0.0033 0.0039
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0014 0.0027 0.0387
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0238 0.0538
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0314 0.1003
Brugia malayi Cathepsin L-like precursor 0.0038 0.0336 0.1153
Brugia malayi hypothetical protein 0.0014 0.0033 0.0114
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0129 0.1502 0.4176
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0094
Echinococcus granulosus microtubule associated protein 2 0.0676 0.8488 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0233 0.0233
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0398 0.1367
Onchocerca volvulus 0.0043 0.0398 0.1326
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0014 0.0033 0.0114
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Schistosoma mansoni cathepsin F (C01 family) 0.0054 0.0546 0.0644
Entamoeba histolytica hypothetical protein 0.0043 0.0407 0.0969
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0297 0.069
Schistosoma mansoni smad 0.0016 0.0055 0.0065
Echinococcus multilocularis geminin 0.0352 0.4344 0.4344
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0297 0.069
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0222 0.2695 0.954
Onchocerca volvulus 0.0014 0.0033 0.0021
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0162 0.1926 0.2269
Mycobacterium leprae Probable lipase LipE 0.0043 0.0398 0.084
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Loa Loa (eye worm) Smad1 0.0016 0.0055 0.0189
Echinococcus multilocularis neuropeptide s receptor 0.0465 0.5791 0.5791
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0014 0.0033 0.0033
Leishmania major cathepsin L-like protease 0.0054 0.0546 0.2765
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0297 0.5
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0026 0.0181 0.0213
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.0546 0.2765
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Schistosoma mansoni hypothetical protein 0.04 0.497 0.5856
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.2841 0.9756
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0297 0.5387
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0297 0.5387
Loa Loa (eye worm) hypothetical protein 0.0043 0.0398 0.1367
Brugia malayi hypothetical protein 0.0014 0.0033 0.0114
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0027 0.0032
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0026 0.0181 0.0393
Schistosoma mansoni jumonji domain containing protein 0.0083 0.0912 0.1075
Brugia malayi Dopamine receptor protein 2 0.0014 0.0033 0.0114
Echinococcus multilocularis dro:myosuppressin receptor 0.0014 0.0033 0.0033
Plasmodium vivax unspecified product 0.003 0.0238 0.4284
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0398 0.0947
Brugia malayi Cathepsin L-like precursor 0.0016 0.0062 0.0212
Brugia malayi PHD-finger family protein 0.0032 0.0259 0.089
Echinococcus granulosus neuropeptides capa receptor 0.0014 0.0033 0.0039
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.032 0.394 1
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0014 0.0027 0.0387
Plasmodium falciparum serine repeat antigen 7 0.0014 0.0027 0.0387
Brugia malayi G protein-coupled receptor F59B2.13 0.0014 0.0033 0.0114
Schistosoma mansoni cathepsin F (C01 family) 0.0054 0.0546 0.0644
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0014 0.0033 0.0033
Trichomonas vaginalis set domain proteins, putative 0.0233 0.2824 0.7147
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0259 0.089
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.0546 0.1326
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0162 0.1926 1
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Loa Loa (eye worm) hypothetical protein 0.0147 0.1728 0.5934
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0033 0.0039
Brugia malayi Serotonin receptor 0.0014 0.0033 0.0114
Trypanosoma cruzi cysteine peptidase, putative 0.0054 0.0546 0.2733
Echinococcus multilocularis neuropeptide Y receptor 0.0014 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0026 0.0181 0.0393
Brugia malayi putative neuropeptide receptor 0.0014 0.0033 0.0114
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0233 0.0274
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0033 0.0039
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0014 0.0033 0.0039
Schistosoma mansoni hypothetical protein 0.0352 0.4344 0.5118
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0524 0.0524
Toxoplasma gondii cathepsin B 0.006 0.0614 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0055 0.0055
Schistosoma mansoni myosin xvIII 0.0014 0.0033 0.0039
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0014 0.0033 0.0039
Leishmania major cathepsin L-like protease 0.0054 0.0546 0.2765
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.1502 0.3769
Loa Loa (eye worm) hypothetical protein 0.0043 0.0398 0.1367
Echinococcus granulosus GPCR family 2 0.0048 0.0465 0.0548
Echinococcus granulosus dnaJ subfamily B 0.04 0.497 0.5856
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.0546 0.1326
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0014 0.0033 0.0039
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0014 0.0027 0.0032
Brugia malayi Papain family cysteine protease containing protein 0.0014 0.0027 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Schistosoma mansoni biogenic amine receptor 0.0014 0.0033 0.0039
Brugia malayi larval opioid receptor 0.0014 0.0033 0.0114
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0465 0.0548
Onchocerca volvulus 0.0233 0.2824 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0398 0.1367
Brugia malayi beta-lactamase family protein 0.0043 0.0398 0.1367
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.003 0.0238 0.028
Plasmodium falciparum serine repeat antigen 6 0.0014 0.0027 0.0387
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0033 0.0039
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0014 0.0033 0.0039
Brugia malayi Smad1 0.0016 0.0055 0.0189
Brugia malayi CXXC zinc finger family protein 0.0028 0.0211 0.0724
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0297 0.5387
Schistosoma mansoni vesicular acetylcholine transporter 0.0222 0.2695 0.3175
Echinococcus multilocularis 6 phosphofructokinase 0.0129 0.1502 0.1502
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0238 0.0538
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0033 0.0033
Schistosoma mansoni cpg binding protein 0.003 0.0231 0.0272
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0524 0.0617
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0239 0.2912 1
Onchocerca volvulus 0.0014 0.0033 0.0021
Brugia malayi MH2 domain containing protein 0.0016 0.0055 0.0189
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0026 0.0181 0.0181
Brugia malayi cathepsin B-like cysteine proteinase 0.0162 0.1926 0.6612
Onchocerca volvulus 0.0014 0.0033 0.0021
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0054 0.0546 0.1876
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.0546 0.1326
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0524 0.0617
Echinococcus granulosus smad 0.0016 0.0055 0.0065
Brugia malayi Melatonin receptor type 1A 0.0014 0.0033 0.0114
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0265 0.0266
Onchocerca volvulus 0.0014 0.0033 0.0021
Echinococcus multilocularis dnaJ subfamily B 0.04 0.497 0.497
Onchocerca volvulus Cathepsin L homolog 0.0054 0.0546 0.1855
Loa Loa (eye worm) ctsf protein 0.0054 0.0546 0.1876
Loa Loa (eye worm) hypothetical protein 0.0032 0.0259 0.089
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.003 0.0238 0.028
Brugia malayi latrophilin 2 splice variant baaae 0.0104 0.1178 0.4046
Brugia malayi Dopamine receptor 0.0014 0.0033 0.0114
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0014 0.0033 0.0039
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0238 0.0538
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0014 0.0027 0.0387
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Brugia malayi cathepsin L-like precursor 0.0038 0.0336 0.1153
Brugia malayi Papain family cysteine protease containing protein 0.0014 0.0027 0.0094
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0014 0.0027 0.0387
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0398 0.0947
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0033 0.0039
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.006 0.0614 0.3093
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0233 0.0274
Toxoplasma gondii cathepsin CPL 0.0054 0.0546 0.8838
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Brugia malayi Cathepsin L-like precursor 0.0038 0.0336 0.1153
Brugia malayi MH2 domain containing protein 0.0016 0.0055 0.0189
Entamoeba histolytica phosphofructokinase, putative 0.0129 0.1502 0.3769
Echinococcus granulosus cathepsin L cysteine protease 0.003 0.0238 0.028
Brugia malayi Tachykinin-like peptides receptor 99D 0.0014 0.0033 0.0114
Loa Loa (eye worm) hypothetical protein 0.0043 0.0398 0.1367
Onchocerca volvulus Cathepsin L homolog 0.0054 0.0546 0.1855
Schistosoma mansoni Smad4 0.0016 0.0055 0.0065
Schistosoma mansoni opsin-like receptor 0.0014 0.0033 0.0039
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0546 0.8834
Echinococcus granulosus geminin 0.0352 0.4344 0.5118
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0014 0.0027 0.0094
Echinococcus granulosus somatostatin receptor 0.0014 0.0033 0.0039
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0222 0.2695 0.9255
Schistosoma mansoni biogenic amine receptor 0.0014 0.0033 0.0039
Leishmania major ATP-dependent phosphofructokinase 0.0129 0.1502 1
Schistosoma mansoni smad1 5 8 and 0.0016 0.0055 0.0065
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0026 0.0181 0.0393
Trypanosoma cruzi cruzipain precursor, putative 0.0054 0.0546 0.2733
Schistosoma mansoni histamine h1 receptor 0.0014 0.0033 0.0039
Entamoeba histolytica cysteine proteinase 2 0.003 0.0238 0.0538
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0033 0.0033
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0054 0.0546 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0026 0.0181 0.0809
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0054 0.0546 1
Brugia malayi Bromodomain containing protein 0.0032 0.0259 0.089
Echinococcus granulosus 6 phosphofructokinase 0.0129 0.1502 0.177
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0108 0.0371
Schistosoma mansoni inositol monophosphatase 0.0036 0.0314 0.0369
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0398 0.0686
Echinococcus multilocularis cathepsin L cysteine protease 0.0054 0.0546 0.0546
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0238 0.0538
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0055 0.0065
Brugia malayi PHD-finger family protein 0.0012 0.0005 0.0017
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.2841 0.9756
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0162 0.1926 0.2269
Echinococcus multilocularis cysteine protease 0.0054 0.0546 0.0546
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0014 0.0033 0.0114
Plasmodium falciparum eukaryotic initiation factor 4A 0.0026 0.0181 0.3233
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0014 0.0033 0.0039
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0014 0.0033 0.0033
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0014 0.0033 0.0114
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0033 0.0039
Schistosoma mansoni hypothetical protein 0.0014 0.0033 0.0039
Mycobacterium ulcerans hypothetical protein 0.0043 0.0398 0.0551
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0014 0.0033 0.0114
Schistosoma mansoni opsin-like receptor 0.0014 0.0033 0.0039
Brugia malayi hypothetical protein 0.0014 0.0033 0.0114
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0273 0.3345 1
Echinococcus multilocularis neuropeptides capa receptor 0.0014 0.0033 0.0033
Echinococcus granulosus cysteine protease 0.003 0.0238 0.028
Onchocerca volvulus 0.0054 0.0546 0.1855
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0156 0.1848 0.5271
Echinococcus multilocularis g protein coupled receptor 0.0014 0.0033 0.0033
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.1502 0.3769
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0026 0.0181 0.0213
Brugia malayi hypothetical protein 0.0014 0.0033 0.0114
Brugia malayi jmjC domain containing protein 0.0104 0.1187 0.4076
Onchocerca volvulus 0.0043 0.0398 0.1326
Echinococcus multilocularis cathepsin b 0.0162 0.1926 0.1926
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0314 0.0731
Brugia malayi hypothetical protein 0.0043 0.0407 0.1396
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0259 0.0305
Loa Loa (eye worm) TYRA-2 protein 0.0014 0.0033 0.0114
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0398 0.0398
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0314 0.1507
Plasmodium falciparum serine repeat antigen 9 0.0014 0.0027 0.0387
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Leishmania major basic transcription factor 3a, putative 0.0034 0.0289 0.0816
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0289 0.5232
Schistosoma mansoni hypothetical protein 0.0014 0.0033 0.0039
Brugia malayi cathepsin L-like cysteine proteinase 0.0014 0.0027 0.0094
Leishmania major cathepsin L-like protease 0.0054 0.0546 0.2765
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.1502 0.3769
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0055 0.0065
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.394 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.394 1
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0289 0.5232
Schistosoma mansoni smad1 5 8 and 0.0016 0.0055 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0398 0.0469
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.0546 0.2765
Brugia malayi Papain family cysteine protease containing protein 0.0014 0.0027 0.0094
Trypanosoma cruzi cysteine peptidase, putative 0.0054 0.0546 0.2733
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0398 0.0551
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0156 0.1848 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0014 0.0033 0.0033
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0297 0.069
Echinococcus granulosus orexin receptor type 2 0.0014 0.0033 0.0039
Loa Loa (eye worm) cathepsin B 0.006 0.0614 0.211
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.003 0.0238 0.028
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0233 0.0274
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0033 0.0039
Brugia malayi cathepsin Z-like cysteine proteinase 0.0014 0.0027 0.0094
Onchocerca volvulus 0.0054 0.0546 0.1855
Schistosoma mansoni hypothetical protein 0.0048 0.0465 0.0548
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0014 0.0033 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0033 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0238 0.0429
Brugia malayi hypothetical protein 0.0014 0.0033 0.0114
Plasmodium vivax serine-repeat antigen (SERA) 0.0014 0.0027 0.0387
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0055 0.0189
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.0546 0.2765
Schistosoma mansoni alpha-1 adrenergic receptor 0.0014 0.0033 0.0039
Leishmania major cathepsin L-like protease 0.0054 0.0546 0.2765
Echinococcus granulosus cathepsin l1 0.0038 0.0336 0.0396
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0026 0.0181 0.0181
Plasmodium falciparum phd finger protein, putative 0.0032 0.0259 0.468
Echinococcus granulosus neuropeptide s receptor 0.0465 0.5791 0.6823
Loa Loa (eye worm) hypothetical protein 0.0026 0.0181 0.0622
Onchocerca volvulus 0.0054 0.0546 0.1855
Mycobacterium tuberculosis Conserved protein 0.0043 0.0398 0.0686
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0014 0.0027 0.0032
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0407 0.0479
Brugia malayi cathepsin F-like cysteine proteinase 0.0014 0.0027 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Echinococcus multilocularis transcription factor btf3 0.0034 0.0289 0.0289
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0026 0.0181 0.0213
Brugia malayi MH1 domain containing protein 0.0016 0.0055 0.0189
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0289 0.0668
Echinococcus multilocularis g-protein coupled receptor 0.0014 0.0033 0.0033
Echinococcus multilocularis peregrin 0.0032 0.0259 0.0259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Schistosoma mansoni hypothetical protein 0.0048 0.0465 0.0548
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0297 0.069
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0129 0.1502 0.7812
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0016 0.0062 0.0212
Entamoeba histolytica phosphofructokinase, putative 0.0129 0.1502 0.3769
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0398 0.0551
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0012 0.0003 0.0003
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0365 0.1255
Echinococcus granulosus cpg binding protein 0.003 0.0231 0.0272
Schistosoma mansoni biogenic amine receptor 0.0014 0.0033 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0062 0.0212
Onchocerca volvulus 0.018 0.2146 0.7577
Mycobacterium ulcerans beta-lactamase 0.0043 0.0398 0.0551
Plasmodium vivax unspecified product 0.0016 0.0062 0.1021
Echinococcus granulosus g protein coupled receptor 0.0014 0.0033 0.0039
Onchocerca volvulus 0.0014 0.0033 0.0021
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0054 0.0546 0.1876
Loa Loa (eye worm) hypothetical protein 0.0038 0.0336 0.1153
Echinococcus granulosus fmrfamide receptor 0.0014 0.0033 0.0039
Giardia lamblia Cathepsin B precursor 0.006 0.0614 0.1501
Schistosoma mansoni amine GPCR 0.0014 0.0033 0.0039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0033 0.0039
Echinococcus granulosus neuropeptide FF receptor 2 0.0014 0.0033 0.0039
Mycobacterium ulcerans 6-phosphofructokinase 0.0129 0.1502 0.7743
Echinococcus granulosus g protein coupled receptor 0.0014 0.0033 0.0039
Echinococcus multilocularis g protein coupled receptor 0.0014 0.0033 0.0033
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0289 0.0992
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0033 0.0039
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0014 0.0027 0.0094
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0033 0.0039
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.006 0.0614 0.3281
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0014 0.0027 0.0387
Mycobacterium tuberculosis Conserved protein 0.0043 0.0398 0.0686
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0233 0.0274
Loa Loa (eye worm) hypothetical protein 0.0152 0.1792 0.6155
Brugia malayi sulfakinin receptor protein 0.0014 0.0033 0.0114
Loa Loa (eye worm) hypothetical protein 0.0104 0.1178 0.4046
Brugia malayi follicle stimulating hormone receptor 0.0239 0.2912 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0054 0.0546 0.0546
Giardia lamblia PHD finger protein 15 0.0032 0.0259 0.0592
Onchocerca volvulus 0.0054 0.0546 0.1855
Brugia malayi Serotonin receptor 0.0014 0.0033 0.0114
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.0546 0.1326
Entamoeba histolytica phosphofructokinase, putative 0.0129 0.1502 0.3769
Onchocerca volvulus 0.0014 0.0033 0.0021
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.0297 0.0309
Schistosoma mansoni hypothetical protein 0.0043 0.0407 0.0479
Brugia malayi Calcitonin receptor-like protein seb-1 0.0152 0.1792 0.6155
Brugia malayi Dopamine receptor protein 1 0.0014 0.0033 0.0114
Loa Loa (eye worm) G-protein coupled receptor 0.0014 0.0033 0.0114
Loa Loa (eye worm) hypothetical protein 0.0055 0.055 0.189
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0398 0.1953
Brugia malayi Papain family cysteine protease containing protein 0.003 0.0238 0.0816
Echinococcus multilocularis neuropeptide receptor 0.0014 0.0033 0.0033
Echinococcus multilocularis cathepsin L 0.003 0.0238 0.0238
Onchocerca volvulus 0.0014 0.0033 0.0021
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0314 0.5
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Loa Loa (eye worm) 6-phosphofructokinase 0.0129 0.1502 0.5158
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0094
Onchocerca volvulus Neuropeptide F receptor homolog 0.0014 0.0033 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.006 0.0614 0.1501
Onchocerca volvulus 0.0054 0.0546 0.1855
Echinococcus multilocularis serotonin receptor 0.0147 0.1728 0.1728
Echinococcus granulosus peregrin 0.0032 0.0259 0.0305
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0524 0.0524
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0297 0.069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0233 0.0274
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.394 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Entamoeba histolytica cysteine proteinase, putative 0.0038 0.0336 0.0789
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0289 0.0668
Echinococcus multilocularis cathepsin L cysteine protease 0.0054 0.0546 0.0546
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Brugia malayi 6-phosphofructokinase 0.0129 0.1502 0.5158
Brugia malayi hypothetical protein 0.0014 0.0033 0.0114
Plasmodium falciparum serine repeat antigen 1 0.0014 0.0027 0.0387
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0014 0.0027 0.0387
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0314 0.4874
Echinococcus multilocularis neuropeptides capa receptor 0.0014 0.0033 0.0033
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0014 0.0033 0.0039
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0014 0.0027 0.0094
Onchocerca volvulus 0.0014 0.0033 0.0021
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0465 0.1598
Brugia malayi neuropeptide F receptor 0.0014 0.0033 0.0114
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0026 0.0181 0.0549
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0524 0.0617
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0465 0.1598
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0014 0.0033 0.0039
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0314 0.0314
Brugia malayi MH2 domain containing protein 0.0234 0.2841 0.9756
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0014 0.0027 0.0387
Schistosoma mansoni amine GPCR 0.0014 0.0033 0.0039
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0233 0.0233
Echinococcus granulosus cathepsin L 0.0014 0.0027 0.0032
Schistosoma mansoni hypothetical protein 0.0014 0.0033 0.0039
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.0546 0.2765
Schistosoma mansoni neuropeptide F-like receptor 0.0014 0.0033 0.0039
Echinococcus granulosus tm gpcr rhodopsin 0.0014 0.0033 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0033 0.0033
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0026 0.0181 0.0393
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0398 0.0469
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0014 0.0027 0.0387
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0027 0.0032
Echinococcus granulosus transcription factor btf3 0.0034 0.0289 0.034
Plasmodium vivax unspecified product 0.0014 0.0027 0.0387
Echinococcus multilocularis G-protein coupled receptor, putative 0.0014 0.0033 0.0033
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0297 0.069
Brugia malayi Pre-SET motif family protein 0.003 0.0233 0.0799
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Echinococcus multilocularis sex peptide receptor 0.0014 0.0033 0.0033
Schistosoma mansoni cathepsin S (C01 family) 0.0014 0.0027 0.0032
Plasmodium falciparum serine repeat antigen 8 0.0014 0.0027 0.0387
Loa Loa (eye worm) neuropeptide F receptor 0.0014 0.0033 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0053 0.0524 0.1798
Echinococcus multilocularis G protein coupled receptor 139 0.0014 0.0033 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0033 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0398 0.7255
Brugia malayi Cathepsin L-like precursor 0.0054 0.0546 0.1876
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0129 0.1502 0.7769
Toxoplasma gondii ABC1 family protein 0.0043 0.0398 0.6314
Brugia malayi RE15519p 0.0014 0.0033 0.0114
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0014 0.0027 0.0032
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0162 0.1926 0.2269
Onchocerca volvulus 0.0043 0.0398 0.1326
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0398 0.0686
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0398 0.0686
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0156 0.1848 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0027 0.0032
Brugia malayi neuropeptide F receptor 0.0014 0.0033 0.0114
Echinococcus granulosus sex peptide receptor 0.0014 0.0033 0.0039
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0398 0.1643
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0398 0.0686
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0014 0.0033 0.0114
Echinococcus granulosus neuropeptide receptor 0.0014 0.0033 0.0039
Schistosoma mansoni neuropeptide receptor 0.0014 0.0033 0.0039
Schistosoma mansoni hypothetical protein 0.0048 0.0465 0.0548
Echinococcus multilocularis allatostatin A receptor 0.0014 0.0033 0.0033
Loa Loa (eye worm) neuropeptide F receptor 0.0014 0.0033 0.0114
Brugia malayi hypothetical protein 0.0014 0.0033 0.0114
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0033 0.0033
Brugia malayi beta-lactamase family protein 0.0043 0.0398 0.1367
Onchocerca volvulus 0.0014 0.0033 0.0021
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0331 0.0776
Brugia malayi G protein-coupled receptor 0.0014 0.0033 0.0114
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0412 0.0485
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0014 0.0033 0.0114
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0014 0.0033 0.0114
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.004 0.0365 0.1252
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.394 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0014 0.0033 0.0033
Echinococcus granulosus cathepsin l1 0.0054 0.0546 0.0644
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0365 0.043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.394 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0152 0.1792 0.6155
Loa Loa (eye worm) hypothetical protein 0.0038 0.0336 0.1153
Echinococcus granulosus neuropeptide receptor A26 0.0465 0.5791 0.6823
Brugia malayi eukaryotic initiation factor 4A 0.0026 0.0181 0.0622
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.006 0.0614 0.0724
Echinococcus granulosus neuropeptide Y receptor 0.0014 0.0033 0.0039
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.004 0.0365 0.1252
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0014 0.0033 0.0033
Brugia malayi hypothetical protein 0.018 0.2146 0.737
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0297 0.4597
Echinococcus granulosus Smad4 0.0016 0.0055 0.0065
Echinococcus multilocularis cathepsin L 0.0014 0.0027 0.0027
Echinococcus granulosus potassium voltage gated channel subfamily H 0.004 0.0365 0.043
Trypanosoma cruzi cysteine protease, putative 0.003 0.0238 0.1108
Brugia malayi vesicular acetylcholine transporter unc-17 0.0222 0.2695 0.9255
Loa Loa (eye worm) hypothetical protein 0.0016 0.0062 0.0212
Schistosoma mansoni hypothetical protein 0.0104 0.1178 0.1388
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0398 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0289 0.0668
Echinococcus granulosus g protein coupled receptor 0.0014 0.0033 0.0039
Echinococcus multilocularis somatostatin receptor 0.0014 0.0033 0.0033
Brugia malayi cathepsin Z-like cysteine proteinase 0.0014 0.0027 0.0094
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0419 0.0493
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0162 0.1926 0.2269
Onchocerca volvulus 0.003 0.0233 0.0734
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0014 0.0027 0.0032
Brugia malayi beta-lactamase 0.0043 0.0398 0.1367
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0014 0.0033 0.0039
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Echinococcus granulosus biogenic amine 5HT receptor 0.0014 0.0033 0.0039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0033 0.0039
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0465 0.0548
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0331 0.0776
Brugia malayi G-protein coupled receptor 0.0014 0.0033 0.0114
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0129 0.1502 0.3515
Plasmodium vivax vivapain-3 0.003 0.0238 0.4284
Schistosoma mansoni microtubule-associated protein tau 0.0676 0.8488 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0398 0.0686
Schistosoma mansoni cpg binding protein 0.0028 0.0211 0.0248
Loa Loa (eye worm) hypothetical protein 0.018 0.2146 0.737
Echinococcus multilocularis g protein coupled receptor 0.0014 0.0033 0.0033
Schistosoma mansoni amine GPCR 0.0014 0.0033 0.0039
Brugia malayi AKH receptor 0.0014 0.0033 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Echinococcus multilocularis neuropeptide FF receptor 2 0.0014 0.0033 0.0033
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0014 0.0033 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0033 0.0039
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0014 0.0027 0.0094
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0014 0.0033 0.0033
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0398 0.084
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0627 0.0739
Onchocerca volvulus 0.0054 0.0546 0.1855
Brugia malayi cathepsin F-like cysteine proteinase 0.0016 0.0062 0.0212
Schistosoma mansoni biogenic amine (5HT) receptor 0.0147 0.1728 0.2036
Entamoeba histolytica cysteine protease, putative 0.0054 0.0546 0.1326
Onchocerca volvulus 0.0014 0.0033 0.0021
Echinococcus granulosus cathepsin l cysteine peptidase 0.0054 0.0546 0.0644
Echinococcus granulosus neuropeptide Y receptor 0.0014 0.0033 0.0039
Echinococcus granulosus 7tm_1 domain containing protein 0.0014 0.0033 0.0039
Brugia malayi ORL1-like opioid receptor 0.0014 0.0033 0.0114
Schistosoma mansoni hypothetical protein 0.0352 0.4344 0.5118
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0524 0.0617
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0014 0.0033 0.0039
Loa Loa (eye worm) cysteine protease 0.0054 0.0546 0.1876
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0314 0.1507
Giardia lamblia Cathepsin B precursor 0.006 0.0614 0.1501
Trypanosoma cruzi cruzipain precursor, putative 0.0016 0.0062 0.018
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Schistosoma mansoni neuropeptide F-like receptor 0.0014 0.0033 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0289 0.0668
Brugia malayi beta-NAC-like protein 0.0034 0.0289 0.0992
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0055 0.0189
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Echinococcus granulosus alpha 1A adrenergic receptor 0.0014 0.0033 0.0039
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0026 0.0181 0.0393
Echinococcus multilocularis fmrfamide receptor 0.0014 0.0033 0.0033
Brugia malayi 6-phosphofructokinase 0.0129 0.1502 0.5158
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0104 0.1187 0.1398
Loa Loa (eye worm) melatonin receptor type 1A 0.0014 0.0033 0.0114
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0014 0.0033 0.0033
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.032 0.394 1
Entamoeba histolytica cysteine proteinase, putative 0.0054 0.0546 0.1326
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0033 0.0039
Trypanosoma cruzi cysteine peptidase, putative 0.003 0.0238 0.1108
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Schistosoma mansoni cathepsin B (C01 family) 0.0014 0.0027 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0054 0.0546 0.1326
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Brugia malayi fibroinase precursor 0.0014 0.0027 0.0094
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0094
Loa Loa (eye worm) hypothetical protein 0.0038 0.0336 0.1153
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0055 0.0055
Plasmodium falciparum cysteine proteinase falcipain 1 0.003 0.0238 0.4284
Leishmania major cathepsin L-like protease 0.0054 0.0546 0.2765
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0026 0.0181 0.2617
Mycobacterium ulcerans lipase LipD 0.0043 0.0398 0.0551
Loa Loa (eye worm) 6-phosphofructokinase 0.0129 0.1502 0.5158
Leishmania major hypothetical protein, conserved 0.0043 0.0398 0.1643
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Echinococcus granulosus G protein coupled receptor 139 0.0014 0.0033 0.0039
Echinococcus multilocularis cathepsin b 0.0162 0.1926 0.1926
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0398 0.0947
Leishmania major cathepsin L-like protease 0.0054 0.0546 0.2765
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0297 0.5387
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0314 0.0731
Schistosoma mansoni transcription factor btf3 0.0034 0.0289 0.034
Onchocerca volvulus 0.0014 0.0033 0.0021
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0297 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0033 0.0039
Plasmodium falciparum serine repeat antigen 2 0.0014 0.0027 0.0387
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0259 0.468
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0398 0.1367
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0014 0.0033 0.0039
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0088 0.0103
Trypanosoma brucei cysteine peptidase C (CPC) 0.006 0.0614 0.3281
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0465 0.1598
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0033 0.0039
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0014 0.0027 0.0387
Brugia malayi Cathepsin L-like precursor 0.0054 0.0546 0.1876
Schistosoma mansoni amine GPCR 0.0014 0.0033 0.0039
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0014 0.0033 0.0033
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0365 0.043
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0259 0.0305
Plasmodium vivax vivapain-2 0.0054 0.0546 1
Plasmodium vivax RNA helicase-1, putative 0.0026 0.0181 0.3233
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0398 0.0947
Brugia malayi MH1 domain containing protein 0.0016 0.0055 0.0189
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0398 0.0469
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.0546 0.1326
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.0546 0.1326
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0014 0.0033 0.0039
Echinococcus multilocularis neuropeptide receptor 0.0014 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Schistosoma mansoni cathepsin F (C01 family) 0.0038 0.0336 0.0396
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0238 0.0538
Brugia malayi Papain family cysteine protease containing protein 0.003 0.0238 0.0816
Loa Loa (eye worm) hypothetical protein 0.0016 0.0062 0.0212
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Onchocerca volvulus 0.0014 0.0033 0.0021
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0693 0.2381
Treponema pallidum fructose-bisphosphate aldolase 0.032 0.394 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0038 0.0336 0.1153
Onchocerca volvulus Alhambra homolog 0.0032 0.0259 0.0829
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.0546 0.2765
Brugia malayi GnHR receptor homolog 0.0014 0.0033 0.0114
Plasmodium falciparum serine repeat antigen 3 0.0014 0.0027 0.0387
Trypanosoma cruzi cysteine peptidase, putative 0.0054 0.0546 0.2733
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0014 0.0027 0.0387
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0297 0.4597
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0152 0.1792 0.6155
Echinococcus granulosus serotonin receptor 0.0014 0.0033 0.0039
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0014 0.0033 0.0114
Schistosoma mansoni neuropeptide receptor 0.0014 0.0033 0.0039
Loa Loa (eye worm) inositol-1 0.0036 0.0314 0.1077
Onchocerca volvulus 0.0054 0.0546 0.1855
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0524 0.0617
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.394 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.0546 0.1326
Echinococcus granulosus tachykinin peptides receptor 99D 0.0014 0.0033 0.0039
Brugia malayi Cathepsin L-like precursor 0.0054 0.0546 0.1876
Schistosoma mansoni cathepsin s 0.0016 0.0062 0.0073
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0014 0.0033 0.0033
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.003 0.0238 0.1108
Loa Loa (eye worm) hypothetical protein 0.0054 0.0546 0.1876
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0289 0.1377
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0314 0.0731
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0336 0.0789
Echinococcus multilocularis smad 0.0016 0.0055 0.0055
Echinococcus granulosus vesicular acetylcholine transporter 0.0222 0.2695 0.3175
Echinococcus granulosus biogenic amine 5HT receptor 0.0147 0.1728 0.2036
Entamoeba histolytica cysteine proteinase 1, putative 0.003 0.0238 0.0538
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.1502 0.3769
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Plasmodium falciparum serine repeat antigen 4 0.0014 0.0027 0.0387
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0314 0.1003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0238 0.0429
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0465 0.0465
Schistosoma mansoni neuropeptide f receptor 76f 0.0014 0.0033 0.0039
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0014 0.0033 0.0039
Schistosoma mansoni smad1 5 8 and 0.0016 0.0055 0.0065
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0062 0.018
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0211 0.0724
Echinococcus granulosus tm gpcr rhodopsin 0.0014 0.0033 0.0039
Plasmodium falciparum cysteine proteinase falcipain 3 0.0054 0.0546 1
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0297 0.069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.0546 0.2765
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0014 0.0027 0.0387
Echinococcus multilocularis neuropeptide receptor A26 0.0465 0.5791 0.5791
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0014 0.0027 0.0387
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0289 0.1377
Echinococcus granulosus eukaryotic initiation factor 4A 0.0026 0.0181 0.0213
Trypanosoma cruzi cysteine proteinase, putative 0.003 0.0238 0.1108
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Onchocerca volvulus 0.0014 0.0033 0.0021
Brugia malayi Cathepsin L-like precursor 0.0054 0.0546 0.1876
Trypanosoma cruzi cysteine proteinase, putative 0.003 0.0238 0.1108
Loa Loa (eye worm) fibroinase 0.0054 0.0546 0.1876
Brugia malayi Inositol-1 0.0036 0.0314 0.1077
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.0546 0.1326
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0014 0.0033 0.0039
Trypanosoma cruzi cysteine peptidase, putative 0.0054 0.0546 0.2733
Schistosoma mansoni cathepsin C 0.0014 0.0027 0.0032
Brugia malayi Papain family cysteine protease containing protein 0.0054 0.0546 0.1876
Loa Loa (eye worm) hypothetical protein 0.0162 0.1926 0.6612
Plasmodium vivax vivapain-2 0.0054 0.0546 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0314 0.0731
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Plasmodium vivax SET domain protein, putative 0.003 0.0233 0.4192
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0062 0.0212
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0211 0.0249
Echinococcus granulosus tm gpcr rhodopsin 0.0014 0.0033 0.0039
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0314 0.0369
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0014 0.0033 0.0033
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0407 0.0407
Brugia malayi phosphofructokinase 0.0129 0.1502 0.5158
Echinococcus granulosus hypothetical protein 0.0014 0.0033 0.0039
Echinococcus multilocularis fmrfamide receptor 0.0014 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0054 0.0546 0.1326
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0259 0.0259
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0238 0.0538
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0365 0.043
Schistosoma mansoni hypothetical protein 0.0048 0.0465 0.0548
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0054 0.0546 0.2765
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.2464 0.8461
Schistosoma mansoni growth hormone secretagogue receptor 0.0014 0.0033 0.0039
Echinococcus multilocularis vesicular acetylcholine transporter 0.0222 0.2695 0.2695
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Echinococcus granulosus allatostatin A receptor 0.0014 0.0033 0.0039
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0259 0.3947
Echinococcus granulosus cathepsin L 0.003 0.0238 0.028
Loa Loa (eye worm) G-protein coupled receptor 0.0014 0.0033 0.0114
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0297 0.069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.394 1
Brugia malayi Pre-SET motif family protein 0.0204 0.2464 0.8461
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0014 0.0027 0.0387
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0027 0.0032
Echinococcus granulosus dro:myosuppressin receptor 0.0014 0.0033 0.0039
Schistosoma mansoni hypothetical protein 0.0014 0.0033 0.0039
Onchocerca volvulus 0.0014 0.0033 0.0021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.394 1
Echinococcus multilocularis cpg binding protein 0.003 0.0231 0.0231
Onchocerca volvulus Cathepsin F homolog 0.0054 0.0546 0.1855
Brugia malayi hypothetical protein 0.0014 0.0033 0.0114
Loa Loa (eye worm) hypothetical protein 0.0048 0.0465 0.1598
Echinococcus multilocularis serotonin receptor 0.0147 0.1728 0.1728
Echinococcus granulosus peptide allatostatin:somatostatin 0.0014 0.0033 0.0039
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0407 0.0479
Loa Loa (eye worm) beta-lactamase 0.0043 0.0398 0.1367
Echinococcus multilocularis microtubule associated protein 2 0.0676 0.8488 0.8488
Loa Loa (eye worm) hypothetical protein 0.003 0.0233 0.0799
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0465 0.0465
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0033 0.0039
Echinococcus granulosus cathepsin b 0.0162 0.1926 0.2269
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0038 0.0336 0.1625
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Entamoeba histolytica hypothetical protein 0.0043 0.0407 0.0969
Echinococcus multilocularis Smad4 0.0016 0.0055 0.0055
Entamoeba histolytica hypothetical protein 0.0034 0.0289 0.0668
Brugia malayi hypothetical protein 0.0014 0.0033 0.0114
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0014 0.0033 0.0039
Schistosoma mansoni inositol monophosphatase 0.0036 0.0314 0.0369
Entamoeba histolytica hypothetical protein 0.0043 0.0407 0.0969
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0345 0.0345
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0336 0.0789
Schistosoma mansoni 6-phosphofructokinase 0.0129 0.1502 0.177
Entamoeba histolytica cysteine protease, putative 0.003 0.0238 0.0538
Onchocerca volvulus 0.0014 0.0033 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0398 0.1953
Mycobacterium tuberculosis Conserved protein 0.0043 0.0398 0.0686
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0419 0.0419
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.004 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0094
Brugia malayi G-protein coupled receptor 0.0014 0.0033 0.0114
Schistosoma mansoni 6-phosphofructokinase 0.0129 0.1502 0.177
Schistosoma mansoni neuropeptide receptor 0.0014 0.0033 0.0039
Echinococcus multilocularis cysteine protease 0.0054 0.0546 0.0546
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0297 0.069
Loa Loa (eye worm) hypothetical protein 0.0035 0.0297 0.1019
Brugia malayi jmjC domain containing protein 0.004 0.0365 0.1255
Plasmodium vivax serine-repeat antigen (SERA) 0.0014 0.0027 0.0387
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0054 0.0546 0.1326
Loa Loa (eye worm) hypothetical protein 0.0147 0.1728 0.5934
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0104 0.1187 0.1187
Onchocerca volvulus 0.0028 0.0211 0.0656
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0233 0.3498
Brugia malayi Cathepsin L-like precursor 0.0054 0.0546 0.1876
Giardia lamblia Cathepsin B precursor 0.006 0.0614 0.1501
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Echinococcus granulosus cathepsin L cysteine proteinase 0.0054 0.0546 0.0644
Schistosoma mansoni hypothetical protein 0.0032 0.0259 0.0305
Onchocerca volvulus 0.0014 0.0033 0.0021
Echinococcus granulosus 7TM GPCR rhodopsin 0.0014 0.0033 0.0039
Echinococcus granulosus neuropeptides capa receptor 0.0014 0.0033 0.0039
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0012 0.0003 0.0004
Schistosoma mansoni neuropeptide receptor 0.0014 0.0033 0.0039
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Echinococcus granulosus cathepsin b 0.0162 0.1926 0.2269
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0014 0.0033 0.0039
Schistosoma mansoni amine GPCR 0.0014 0.0033 0.0039
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Loa Loa (eye worm) hypothetical protein 0.0043 0.0398 0.1367
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0014 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0094
Loa Loa (eye worm) phosphofructokinase 0.0129 0.1502 0.5158
Brugia malayi Cathepsin L-like precursor 0.0054 0.0546 0.1876
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0412 0.0485
Onchocerca volvulus 0.0038 0.0336 0.1103
Plasmodium vivax vivapain-1 0.003 0.0238 0.4284
Entamoeba histolytica cysteine proteinase, putative 0.0054 0.0546 0.1326
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0055 0.0065
Echinococcus granulosus g-protein coupled receptor 0.0014 0.0033 0.0039
Giardia lamblia Fructose-bisphosphate aldolase 0.032 0.394 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0114
Leishmania major cathepsin L-like protease 0.0054 0.0546 0.2765

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 7.3078 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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