Detailed information for compound 1537289

Basic information

Technical information
  • TDR Targets ID: 1537289
  • Name: 1-(2-phenylethyl)-3-pyrimidin-2-ylthiourea
  • MW: 258.342 | Formula: C13H14N4S
  • H donors: 2 H acceptors: 2 LogP: 2.1 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: S=C(Nc1ncccn1)NCCc1ccccc1
  • InChi: 1S/C13H14N4S/c18-13(17-12-14-8-4-9-15-12)16-10-7-11-5-2-1-3-6-11/h1-6,8-9H,7,10H2,(H2,14,15,16,17,18)
  • InChiKey: FSTGGFKTMZRTEN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(2-phenylethyl)-3-pyrimidin-2-yl-thiourea
  • 1-(2-phenylethyl)-3-(2-pyrimidinyl)thiourea
  • 5454-37-5
  • NSC23098

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.5 %
Plasmodium berghei dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 26.9 %
Leishmania donovani acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Onchocerca volvulus Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 57.3 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin reductase 1, cytoplasmic   499 aa 464 aa 24.8 %
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.5 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Leishmania mexicana 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 452 aa 25.7 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin reductase 1, cytoplasmic   499 aa 506 aa 23.7 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.9 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 529 aa 31.8 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.3 %
Plasmodium falciparum thioredoxin reductase Thioredoxin reductase 1, cytoplasmic   499 aa 511 aa 45.2 %
Leishmania infantum dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 462 aa 25.8 %
Plasmodium falciparum glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 500 aa 32.2 %
Neospora caninum hypothetical protein Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.0 %
Trypanosoma brucei dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.4 %
Leishmania major acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 460 aa 25.4 %
Leishmania braziliensis acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 22.8 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.5 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, point mutation,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.3 %
Leishmania donovani dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.6 %
Leishmania infantum acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Leishmania mexicana acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 24.4 %
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.2 %
Leishmania braziliensis dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 488 aa 21.9 %
Neospora caninum glutathione reductase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 32.7 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.3 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 518 aa 24.9 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.2 %
Leishmania braziliensis 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 450 aa 25.6 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 539 aa 22.3 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 540 aa 23.3 %
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 454 aa 25.3 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 519 aa 23.7 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0624 0.1132
Schistosoma mansoni hypothetical protein 0.0174 0.1796 0.5397
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0067 0.0647 0.1945
Brugia malayi hypothetical protein 0.0031 0.0254 0.1001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0048 0.0145
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.0152 0.0276
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.0152 0.0458
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Giardia lamblia Replication factor C, subunit 1 0.0012 0.0048 0.0764
Schistosoma mansoni histidyl-tRNA synthetase 0.0007 0 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0031 0.0254 0.1656
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0536 0.3572
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.0152 0.0458
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0071 0.0281
Echinococcus granulosus hypothetical protein 0.0022 0.0152 0.0276
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0038 0.0508
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0071 0.0129
Schistosoma mansoni sugar transporter 0.0031 0.0254 0.0763
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0144 0.0599
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0152 0.0458
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.002 0.0134 0.5256
Brugia malayi ORL1-like opioid receptor 0.0022 0.0152 0.06
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0152 0.0458
Brugia malayi topoisomerase 0.0012 0.0048 0.019
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Echinococcus granulosus neuropeptide s receptor 0.0519 0.5514 1
Brugia malayi Pre-SET motif family protein 0.0203 0.2108 0.8304
Echinococcus granulosus bloom syndrome protein 0.0021 0.0144 0.0262
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Trypanosoma brucei glucose transporter, putative 0.0068 0.0657 0.8747
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0054 0.0715
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0053 0.0706
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0152 0.0458
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0134 0.1779
Trypanosoma brucei glucose transporter 1E 0.0068 0.0657 0.8747
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0234 0.0703
Onchocerca volvulus 0.0022 0.0152 0.0592
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0155 0.0155
Brugia malayi major facilitator superfamily protein 0.0031 0.0254 0.1001
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.1325 0.8935
Loa Loa (eye worm) hypothetical protein 0.0012 0.0054 0.0161
Schistosoma mansoni glucose transport protein 0.022 0.2295 0.6896
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.1174
Schistosoma mansoni amine GPCR 0.0022 0.0152 0.0458
Echinococcus granulosus somatostatin receptor 0.0022 0.0152 0.0276
Echinococcus granulosus single minded 2 0.0035 0.0299 0.0541
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0067 0.0647 0.1174
Echinococcus multilocularis somatostatin receptor 0.0022 0.0152 0.0276
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.001 0.0026 0.0345
Schistosoma mansoni glucose transport protein 0.022 0.2295 0.6896
Trypanosoma brucei histidyl-tRNA synthetase 0.0007 0 0.0005
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0031 0.0254 0.5643
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0007 0 0.0001
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.0152 0.0458
Trypanosoma brucei glucose transporter 2A 0.0068 0.0657 0.8747
Brugia malayi Sugar transporter family protein 0.0031 0.0254 0.1001
Brugia malayi hypothetical protein 0.0119 0.12 0.4726
Schistosoma mansoni hypothetical protein 0.022 0.2295 0.6896
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.01 0.0182
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0657 0.2725
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.1325 0.8935
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0152 0.0276
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0144 0.0599
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.0152 0.0592
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Plasmodium falciparum calcium-dependent protein kinase 2 0.0067 0.0648 0.0648
Treponema pallidum threonyl-tRNA synthetase 0.0012 0.0054 0.3127
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0038 0.0158
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0007 0 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0008 0.001 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.2295 0.4162
Onchocerca volvulus 0.0031 0.0254 0.1015
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0486 0.0734
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.01 0.0182
Schistosoma mansoni sugar transporter 0.0031 0.0254 0.0763
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0134 0.2966
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0038 0.0508
Brugia malayi hypoxia-induced factor 1 0.0147 0.1503 0.5921
Echinococcus multilocularis General substrate transporter 0.0189 0.1961 0.3557
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0155 0.2065
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0356 0.3758 0.3758
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0117 0.0117
Toxoplasma gondii protein kinase, putative 0.0622 0.663 1
Echinococcus granulosus General substrate transporter 0.0189 0.1961 0.3557
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0049 0.045 0.1868
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0038 0.0158
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Echinococcus multilocularis nibrin 0.0012 0.0048 0.0088
Echinococcus granulosus aryl hydrocarbon receptor 0.0012 0.0053 0.0096
Echinococcus multilocularis histidyl tRNA synthetase 0.0007 0 0.0001
Onchocerca volvulus 0.0022 0.0152 0.0592
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0152 0.0276
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.0751 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0134 0.0134
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0624 0.2459
Brugia malayi DKFZp564C0469 protein 0.0012 0.0048 0.019
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Brugia malayi hypothetical protein 0.0012 0.0048 0.019
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0012 0.0053 0.0159
Plasmodium vivax lysine--tRNA ligase, putative 0.0049 0.045 0.045
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Plasmodium vivax proline--tRNA ligase, putative 0.0077 0.0751 0.0751
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.0152 0.06
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0647 0.1945
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.1325 0.8935
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0053 0.022
Trypanosoma cruzi hexose transporter, putative 0.0037 0.0323 0.4299
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0486 0.648
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Brugia malayi RE15519p 0.0022 0.0152 0.06
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.002 0.0134 0.1779
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0152 0.0458
Loa Loa (eye worm) hypothetical protein 0.0065 0.0624 0.1875
Loa Loa (eye worm) hypothetical protein 0.0014 0.0072 0.0218
Brugia malayi GnHR receptor homolog 0.0022 0.0152 0.06
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.0152 0.0276
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0155 0.0155
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0054 0.0097
Echinococcus granulosus replication factor c subunit 1 0.0012 0.0048 0.0088
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0054 0.0108
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Leishmania major glucose transporter, lmgt1 0.0068 0.0657 0.8747
Echinococcus multilocularis serotonin receptor 0.0022 0.0152 0.0276
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0054 0.0081
Plasmodium falciparum thioredoxin reductase 0.0057 0.0536 0.0536
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Plasmodium falciparum importin beta, putative 0.003 0.0239 0.0239
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.0152 0.0458
Schistosoma mansoni adenoreceptor 0.0022 0.0152 0.0458
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Onchocerca volvulus 0.0022 0.0152 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0071 0.0129
Loa Loa (eye worm) hypothetical protein 0.0012 0.0053 0.0159
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.002 0.0134 0.5256
Leishmania major histidyl-tRNA synthetase, putative 0.0007 0 0.0005
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0043 0.0385 0.1597
Treponema pallidum NADH oxidase 0.002 0.0134 0.7773
Schistosoma mansoni sugar transporter 0.0031 0.0254 0.0763
Giardia lamblia Glycyl-tRNA synthetase 0.0012 0.0054 0.0849
Brugia malayi hypothetical protein 0.0022 0.0152 0.06
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0254 0.1001
Echinococcus granulosus g protein coupled receptor 0.0022 0.0152 0.0276
Schistosoma mansoni opsin-like receptor 0.0022 0.0152 0.0458
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0012 0.0048 0.0073
Echinococcus multilocularis GPCR, family 2 0.0065 0.0624 0.1132
Onchocerca volvulus 0.0031 0.0254 0.1015
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0066 0.0633 0.9773
Onchocerca volvulus 0.0031 0.0254 0.1015
Mycobacterium tuberculosis Probable reductase 0.013 0.1325 0.8935
Onchocerca volvulus 0.0031 0.0254 0.1015
Trypanosoma brucei glucose transporter, putative 0.0068 0.0657 0.8747
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0454 0.1789
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0012 0.0053 0.0096
Onchocerca volvulus 0.0022 0.0152 0.0592
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0152 0.0458
Chlamydia trachomatis lysine--tRNA ligase 0.0049 0.045 1
Brugia malayi larval opioid receptor 0.0022 0.0152 0.06
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Schistosoma mansoni hypothetical protein 0.005 0.0454 0.1364
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0015 0.0077 0.0303
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0179 0.0743
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0054 0.0161
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0053 0.022
Echinococcus multilocularis survival motor neuron protein 1 0.0243 0.2538 0.4603
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0048 0.0201
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0694 0.1259
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0152 0.0276
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0134 0.0134
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0624 0.2459
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0206 0.2145 0.6446
Loa Loa (eye worm) hypothetical protein 0.0053 0.0486 0.1462
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Onchocerca volvulus Putative transporter 0.0031 0.0254 0.1015
Brugia malayi RNA, U transporter 1 0.0084 0.0828 0.3262
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0067 0.0648 0.0977
Schistosoma mansoni netrin receptor unc5 0.0014 0.0071 0.0214
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0015 0.0077 0.0303
Trichomonas vaginalis mercuric reductase, putative 0.002 0.0134 0.0554
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0254 0.0763
Trichomonas vaginalis CAMK family protein kinase 0.0067 0.0647 0.2686
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0054 0.0097
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0038 0.0508
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.1174
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.0152 0.0276
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0007 0 0.0001
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2295 0.4162
Onchocerca volvulus 0.0022 0.0152 0.0592
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0012 0.0048 0.0644
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.0152 0.06
Brugia malayi Uncoordinated protein 44 0.0014 0.0071 0.0281
Plasmodium vivax sugar transporter, putative 0.0031 0.0254 0.0254
Mycobacterium ulcerans arylsulfatase, AslA 0.0008 0.001 0.0229
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0152 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Onchocerca volvulus 0.0012 0.0053 0.0178
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0536 0.0972
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0145 0.1482 1
Onchocerca volvulus 0.0035 0.0299 0.12
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0134 0.0134
Schistosoma mansoni topbp1 0.0012 0.0048 0.0145
Brugia malayi Death domain containing protein 0.0014 0.0071 0.0281
Schistosoma mansoni chromosome transmission fidelity factor 0.0012 0.0048 0.0145
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0134 0.1779
Loa Loa (eye worm) hypothetical protein 0.0159 0.1636 0.4915
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Schistosoma mansoni opsin-like receptor 0.0022 0.0152 0.0458
Brugia malayi glutathione reductase 0.0057 0.0536 0.2112
Echinococcus granulosus solute carrier family 22 0.0031 0.0254 0.0461
Schistosoma mansoni amine GPCR 0.0022 0.0152 0.0458
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0152 0.0276
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0038 0.0333 0.4435
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0657 0.8747
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Schistosoma mansoni hypothetical protein 0.0065 0.0624 0.1875
Echinococcus granulosus GPCR family 2 0.0065 0.0624 0.1132
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0152 0.0276
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0012 0.0053 0.0096
Toxoplasma gondii ATPase, AAA family protein 0.0012 0.0048 0.0073
Brugia malayi hypothetical protein 0.0159 0.1636 0.6444
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.0152 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0254 0.1054
Schistosoma mansoni glucose transport protein 0.022 0.2295 0.6896
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0013 0.005
Brugia malayi Calcitonin receptor-like protein seb-1 0.0206 0.2145 0.8452
Trichomonas vaginalis glucose transporter, putative 0.0068 0.0657 0.2725
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0031 0.0254 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.0152 0.0592
Onchocerca volvulus 0.0022 0.0152 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus granulosus neuropeptide receptor 0.0022 0.0152 0.0276
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0152 0.0276
Brugia malayi PAS domain containing protein 0.0047 0.0431 0.17
Schistosoma mansoni opsin-like receptor 0.0022 0.0152 0.0458
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0152 0.0276
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0254 0.1001
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0066 0.0633 0.1901
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0054 0.0161
Schistosoma mansoni sugar transporter 0.0031 0.0254 0.0763
Loa Loa (eye worm) hypothetical protein 0.0243 0.2538 0.7626
Giardia lamblia Hypothetical protein 0.0008 0.001 0.0163
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.004 0.0166
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0067 0.0648 0.0648
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0017 0.0098 0.1311
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Brugia malayi Sugar transporter family protein 0.022 0.2295 0.9042
Leishmania major glycyl tRNA synthetase, putative 0.0007 0 0.0005
Trypanosoma brucei sugar transporter, putative 0.0031 0.0254 0.3384
Entamoeba histolytica recQ family helicase, putative 0.0011 0.004 0.0617
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.1174
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0012 0.0053 0.022
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Schistosoma mansoni hypothetical protein 0.0014 0.0071 0.0214
Trypanosoma cruzi sugar transporter, putative 0.0031 0.0254 0.3384
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0012 0.0048 0.007
Brugia malayi hypothetical protein 0.0022 0.0152 0.06
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0152 0.0458
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.01 0.1334
Brugia malayi Pre-SET motif family protein 0.0029 0.0234 0.0921
Trypanosoma brucei glucose transporter, putative 0.0068 0.0657 0.8747
Echinococcus granulosus death domain containing protein 0.0014 0.0071 0.0129
Echinococcus granulosus nibrin 0.0012 0.0048 0.0088
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0012 0.0053 0.022
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0049 0.045 0.2854
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0048 0.0201
Schistosoma mansoni single-minded 0.0047 0.0431 0.1296
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0234 0.0703
Giardia lamblia Hypothetical protein 0.0008 0.001 0.0163
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0017 0.0098 0.1311
Onchocerca volvulus 0.0231 0.2411 1
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0066 0.0633 0.2492
Plasmodium vivax calcium-dependent protein kinase, putative 0.0067 0.0648 0.0648
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0048 0.0201
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0152 0.0276
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.0152 0.0276
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0134 0.0526
Schistosoma mansoni biogenic amine receptor 0.0022 0.0152 0.0458
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Loa Loa (eye worm) hypothetical protein 0.0066 0.0633 0.1901
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.0152 0.0276
Brugia malayi sulfakinin receptor protein 0.0022 0.0152 0.06
Loa Loa (eye worm) glutathione reductase 0.0057 0.0536 0.161
Schistosoma mansoni neuropeptide receptor 0.0022 0.0152 0.0458
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0054 0.0715
Onchocerca volvulus 0.0012 0.0048 0.0158
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.2295 0.4162
Brugia malayi hypothetical protein 0.0022 0.0152 0.06
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0066 0.0633 0.4118
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Echinococcus granulosus solute carrier family 22 0.0031 0.0254 0.0461
Loa Loa (eye worm) hypothetical protein 0.0012 0.0048 0.0145
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0152 0.0276
Loa Loa (eye worm) hypothetical protein 0.0014 0.0071 0.0214
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.007 0.0106
Loa Loa (eye worm) sugar transporter 0.022 0.2295 0.6896
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.0751 1
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0144 0.0262
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0012 0.0048 0.0747
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.004 0.0532
Plasmodium falciparum protein kinase 7 0.0622 0.663 0.663
Schistosoma mansoni DNA helicase recq5 0.0009 0.0013 0.0038
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0486 0.648
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0134 0.0134
Brugia malayi AKH receptor 0.0022 0.0152 0.06
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0031 0.0254 0.3384
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.0152 0.0276
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.0152 0.0458
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.0152 0.0276
Toxoplasma gondii facilitative glucose transporter GT1 0.022 0.2295 0.3462
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0134 0.1779
Brugia malayi putative neuropeptide receptor 0.0022 0.0152 0.06
Onchocerca volvulus 0.0022 0.0152 0.0592
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0012 0.0053 0.1177
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0152 0.0458
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Brugia malayi Thioredoxin reductase 0.0057 0.0536 0.2112
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0031 0.0254 0.0763
Loa Loa (eye worm) hypothetical protein 0.0017 0.0099 0.0297
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0144 0.0569
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Echinococcus granulosus Ankyrin 0.0014 0.0072 0.0131
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0152 0.0458
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0134 0.1779
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.0152 0.0276
Onchocerca volvulus 0.0022 0.0152 0.0592
Schistosoma mansoni DNA ligase IV 0.0012 0.0048 0.0145
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0134 0.1779
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0054 0.1193
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.0152 0.06
Brugia malayi Sugar transporter family protein 0.0031 0.0254 0.1001
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0657 0.8747
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0067 0.0648 0.0977
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0152 0.0458
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0152 0.0276
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.0152 0.0458
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0038 0.0158
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Schistosoma mansoni ran 0.0022 0.0155 0.0466
Schistosoma mansoni hypothetical protein 0.0022 0.0152 0.0458
Onchocerca volvulus 0.0022 0.0152 0.0592
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0054 0.0715
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.01 0.0182
Leishmania major protein kinase, putative 0.0067 0.0647 0.8623
Plasmodium falciparum hexose transporter 0.022 0.2295 0.2295
Onchocerca volvulus 0.0031 0.0254 0.1015
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.0152 0.0276
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0657 0.8747
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.01 0.01
Trypanosoma brucei glucose transporter, putative 0.0068 0.0657 0.8747
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0486 0.0486
Echinococcus granulosus allatostatin A receptor 0.0022 0.0152 0.0276
Brugia malayi hypothetical protein 0.0012 0.0048 0.019
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2295 0.4162
Mycobacterium ulcerans hypothetical protein 0.0011 0.0038 0.0848
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0254 0.3384
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0067 0.0647 0.255
Brugia malayi hypothetical protein 0.0053 0.0486 0.1917
Mycobacterium ulcerans integral membrane transport protein 0.0031 0.0254 0.5643
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.0152 0.0276
Echinococcus multilocularis sex peptide receptor 0.0022 0.0152 0.0276
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0239 0.3188
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Plasmodium falciparum replication factor C subunit 1, putative 0.0012 0.0048 0.0048
Schistosoma mansoni hypothetical protein 0.0174 0.1796 0.5397
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0053 0.0706
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0054 0.0715
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.0152 0.0458
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Onchocerca volvulus 0.0031 0.0254 0.1015
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0134 0.2966
Brugia malayi follicle stimulating hormone receptor 0.0022 0.0152 0.06
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0031
Mycobacterium tuberculosis Probable oxidoreductase 0.0145 0.1482 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0097 0.0292
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.1174
Brugia malayi hypothetical protein 0.0022 0.0152 0.06
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.0152 0.06
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0486 0.0486
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0152 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0254 0.1054
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0027 0.0213 0.0639
Trichomonas vaginalis glucose transporter, putative 0.0068 0.0657 0.2725
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0152 0.0458
Plasmodium falciparum calcium-dependent protein kinase 1 0.0067 0.0648 0.0648
Leishmania major GTP-binding protein, putative 0.0022 0.0155 0.2065
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.0013 0.0201
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.0152 0.0276
Plasmodium vivax SET domain protein, putative 0.0029 0.0234 0.0234
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0145 0.1482 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0134 0.0837
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0013 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0254 0.1054
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0152 0.0458
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2295 0.4162
Toxoplasma gondii lysine-tRNA ligase 0.0049 0.045 0.0679
Plasmodium falciparum lysine--tRNA ligase 0.0049 0.045 0.045
Schistosoma mansoni topbp1 0.0012 0.0048 0.0145
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Schistosoma mansoni neuropeptide receptor 0.0022 0.0152 0.0458
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0234 0.0353
Mycobacterium ulcerans arylsulfatase AtsB 0.0008 0.001 0.0229
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0152 0.0276
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0011 0.0038 0.0058
Echinococcus granulosus g protein coupled receptor 0.0022 0.0152 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0657 0.2725
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.01 0.1334
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.01 0.1334
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0053 0.022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus granulosus snurportin 1 0.0316 0.3328 0.6036
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0152 0.0276
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0007 0 0.0005
Echinococcus granulosus importin subunit beta 1 0.003 0.0239 0.0434
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0134 0.1779
Leishmania major myo-inositol/proton symporter (MIT) 0.0031 0.0254 0.3384
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0049 0.045 0.5997
Brugia malayi hypothetical protein 0.0022 0.0152 0.06
Mycobacterium ulcerans arylsulfatase AtsD 0.0008 0.001 0.0229
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0042 0.037 0.2301
Giardia lamblia NADH oxidase lateral transfer candidate 0.002 0.0134 0.2111
Echinococcus multilocularis neuropeptide receptor A26 0.0519 0.5514 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.0152 0.0276
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0031 0.0254 0.5643
Plasmodium falciparum threonine--tRNA ligase 0.0012 0.0054 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.01 0.0182
Mycobacterium tuberculosis Conserved hypothetical protein 0.0011 0.0038 0.0189
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.0172 1
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0049 0.045 0.5997
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0624 0.1132
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0134 0.1779
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0254 0.0763
Leishmania major hypothetical protein, conserved 0.0011 0.0038 0.0508
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0152 0.0458
Trichomonas vaginalis myo-inositol transporter, putative 0.0031 0.0254 0.1054
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0624 0.1875
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.0054 0.0212
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0048 0.0201
Echinococcus granulosus serotonin receptor 0.0022 0.0152 0.0276
Onchocerca volvulus 0.0031 0.0254 0.1015
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0145 0.1482 1
Chlamydia trachomatis proline--tRNA ligase 0.0023 0.0172 0.3815
Loa Loa (eye worm) hypothetical protein 0.003 0.0239 0.0719
Trypanosoma brucei glucose transporter, putative 0.0068 0.0657 0.8747
Echinococcus multilocularis replication factor c subunit 1 0.0012 0.0048 0.0088
Trichomonas vaginalis replication factor C large subunit, putative 0.0012 0.0048 0.0201
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0694 0.1259
Schistosoma mansoni amine GPCR 0.0022 0.0152 0.0458
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.2295 0.4162
Echinococcus multilocularis synaptic vesicle 2 protein 0.0031 0.0254 0.0461
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.0152 0.0276
Brugia malayi hypothetical protein 0.0243 0.2538 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0234 0.0424
Echinococcus granulosus g protein coupled receptor 0.0022 0.0152 0.0276
Schistosoma mansoni importin beta-1 0.003 0.0239 0.0719
Giardia lamblia Hexose transporter 0.0031 0.0254 0.4016
Brugia malayi Cam kinase protein 1 0.0067 0.0647 0.255
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0134 0.0242
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0152 0.0458
Plasmodium falciparum calcium-dependent protein kinase 3 0.0067 0.0648 0.0648
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0012 0.0048 0.1902
Onchocerca volvulus 0.0031 0.0254 0.1015
Echinococcus granulosus sex peptide receptor 0.0022 0.0152 0.0276
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.0054 0.0212
Toxoplasma gondii thioredoxin reductase 0.0057 0.0536 0.0808
Brugia malayi Serotonin receptor 0.0022 0.0152 0.06
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0012 0.0054 0.083
Onchocerca volvulus 0.0031 0.0254 0.1015
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0012 0.0054 0.2114
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0013 0.0023
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0657 0.8747
Toxoplasma gondii anticodon binding domain-containing protein 0.0007 0 0.0001
Giardia lamblia Threonyl-tRNA synthetase 0.0012 0.0054 0.0849
Echinococcus granulosus fmrfamide receptor 0.0022 0.0152 0.0276
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0152 0.0276
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Trypanosoma brucei glucose transporter, putative 0.0068 0.0657 0.8747
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0048 0.0644
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0054 0.0223
Echinococcus multilocularis aryl hydrocarbon receptor 0.0012 0.0053 0.0096
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0657 0.8747
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.0751 1
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0038 0.0508
Leishmania major trypanothione reductase 0.0057 0.0536 0.714
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Onchocerca volvulus 0.0031 0.0254 0.1015
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0053 0.022
Leishmania major lysyl-tRNA synthetase, putative 0.0049 0.045 0.5997
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0071 0.0214
Trypanosoma cruzi hexose transporter 0.0068 0.0657 0.8747
Brugia malayi Serotonin receptor 0.0022 0.0152 0.06
Onchocerca volvulus 0.0029 0.0234 0.0931
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0155 0.0281
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0023 0.0172 0.3815
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Schistosoma mansoni hypothetical protein 0.0316 0.3328 1
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0071 0.0129
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.01 0.0151
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.0152 0.0276
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0031 0.0254 0.0461
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0179 0.2384
Echinococcus granulosus sodium channel protein 0.0038 0.0333 0.0604
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0134 0.1779
Echinococcus multilocularis solute carrier family 22 0.0031 0.0254 0.0461
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.0152 0.0276
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0155 0.2065
Loa Loa (eye worm) sugar transporter 0.0031 0.0254 0.0763
Trichomonas vaginalis conserved hypothetical protein 0.022 0.2295 0.9523
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0031 0.0254 0.0254
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.0152 0.0458
Trichomonas vaginalis ran, putative 0.0022 0.0155 0.0643
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0536 0.714
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0155 0.0611
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.0152 0.0276
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.1325 0.8914
Loa Loa (eye worm) hypothetical protein 0.0206 0.2145 0.6446
Trichomonas vaginalis set domain proteins, putative 0.0231 0.241 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0356 0.3758 0.5668
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.0152 0.06
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0048 0.0644
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.0152 0.0276
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0012 0.0054 0.083
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0053 0.0706
Echinococcus multilocularis lysyl tRNA synthetase 0.0049 0.045 0.0817
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0053 0.022
Mycobacterium ulcerans arylsulfatase AtsD 0.0008 0.001 0.0229
Plasmodium falciparum thioredoxin reductase 0.002 0.0134 0.0134
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.0152 0.0458
Echinococcus multilocularis snurportin 1 0.0316 0.3328 0.6036
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.1325 0.8935
Schistosoma mansoni protein kinase 0.0067 0.0647 0.1945
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.0152 0.0276
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0038 0.0333 0.0604
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0066 0.0633 0.2625
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0152 0.0276
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.0152 0.0276
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0134 0.1779
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0174 0.0316
Chlamydia trachomatis DNA ligase 0.0012 0.0048 0.1073
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0007 0 0.0014
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0067 0.0647 0.8623
Loa Loa (eye worm) hypothetical protein 0.0309 0.3255 0.978
Leishmania major importin beta-1 subunit, putative 0.0024 0.0179 0.2384
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0222 0.0403
Onchocerca volvulus 0.0031 0.0254 0.1015
Leishmania major glucose transporter/membrane transporter D2, putative 0.0068 0.0657 0.8747
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Schistosoma mansoni histidyl-tRNA synthetase 0.0007 0 0.0001
Schistosoma mansoni DNA helicase recq1 0.0009 0.0013 0.0038
Loa Loa (eye worm) hypothetical protein 0.0029 0.0234 0.0703
Schistosoma mansoni hypothetical protein 0.0141 0.1441 0.433
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0012 0.0054 0.2114
Trypanosoma cruzi trypanothione reductase, putative 0.002 0.0134 0.1779
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.0152 0.06
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0054 0.0081
Loa Loa (eye worm) hypothetical protein 0.0067 0.0647 0.1945
Plasmodium falciparum calcium-dependent protein kinase 4 0.0067 0.0648 0.0648
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0234 0.0424
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0152 0.0458
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0008 0.001 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0152 0.0458
Trypanosoma brucei glucose transporter, putative 0.0068 0.0657 0.8747
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0012 0.0048 0.0644
Plasmodium falciparum calcium-dependent protein kinase 5 0.0067 0.0648 0.0648
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0067 0.0648 0.0648
Brugia malayi Dopamine receptor 0.0022 0.0152 0.06
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0038 0.0508
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0152 0.0276
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0152 0.0458
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0007 0 0.0001
Entamoeba histolytica hypothetical protein 0.0024 0.0179 0.2764
Leishmania major protein kinase, putative 0.0017 0.0098 0.1311
Leishmania major glucose transporter, lmgt3 0.0068 0.0657 0.8747
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0048 0.0201
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0067 0.0648 0.0648
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.2108 0.6333
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0013 0.0023
Treponema pallidum DNA ligase (lig) 0.0012 0.0048 0.2813
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Echinococcus multilocularis serotonin receptor 0.0022 0.0152 0.0276
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Brugia malayi G protein-coupled receptor 0.0022 0.0152 0.06
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0134 0.0401
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Trypanosoma cruzi FHA domain containing protein, putative 0.0012 0.0048 0.0644
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0152 0.0276
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Schistosoma mansoni hypothetical protein 0.0022 0.0152 0.0458
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0152 0.0458
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0234 0.0703
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0042 0.037 0.2446
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0066 0.0633 0.1147
Loa Loa (eye worm) hypothetical protein 0.0066 0.0633 0.1901
Leishmania major hypothetical protein, conserved 0.0053 0.0486 0.648
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0155 0.0234
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0013 0.005
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.01 0.1334
Trypanosoma brucei glucose transporter, putative 0.0068 0.0657 0.8747
Trichomonas vaginalis sugar transport protein, putative 0.0031 0.0254 0.1054
Echinococcus multilocularis Ankyrin 0.0014 0.0072 0.0131
Loa Loa (eye worm) hypothetical protein 0.0008 0.001 0.0031
Echinococcus granulosus orexin receptor type 2 0.0022 0.0152 0.0276
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.01 0.0611
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.0152 0.0276
Brugia malayi Protein kinase domain containing protein 0.0018 0.0117 0.0459
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0657 0.8747
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0299 0.6631
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.002 0.0134 0.2966
Brugia malayi hypothetical protein 0.0022 0.0152 0.06
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0152 0.0276
Schistosoma mansoni hypothetical protein 0.0022 0.0152 0.0458
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0179 0.0743
Brugia malayi neuropeptide F receptor 0.0022 0.0152 0.06
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0134 0.1779
Leishmania major hypothetical protein, conserved 0.0031 0.0254 0.3384
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0067 0.0647 0.1945
Onchocerca volvulus 0.005 0.0454 0.1848
Brugia malayi Dopamine receptor protein 2 0.0022 0.0152 0.06
Schistosoma mansoni survival motor neuron protein 0.005 0.0454 0.1364
Loa Loa (eye worm) hypothetical protein 0.0141 0.1441 0.433
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0054 0.1193
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0072 0.0218
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.0152 0.0458
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0031 0.0254 0.1656
Echinococcus multilocularis importin subunit beta 1 0.003 0.0239 0.0434
Loa Loa (eye worm) hypothetical protein 0.0012 0.0048 0.0145
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0431 0.1296
Echinococcus granulosus solute carrier family 22 0.0031 0.0254 0.0461
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0013 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0152 0.0458
Treponema pallidum glycyl-tRNA synthetase 0.0007 0 0.002
Brugia malayi G-protein coupled receptor 0.0022 0.0152 0.06
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0254 0.1054
Entamoeba histolytica hypothetical protein 0.0049 0.045 0.6955
Schistosoma mansoni glucose transporter 0.0031 0.0254 0.0763
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0013 0.0019
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0152 0.0276
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.0152 0.06
Onchocerca volvulus 0.0022 0.0152 0.0592
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.0152 0.0458
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.0152 0.0458
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0072 0.0072
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.0152 0.0458
Onchocerca volvulus 0.0031 0.0254 0.1015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Onchocerca volvulus 0.0031 0.0254 0.1015
Entamoeba histolytica protein kinase, putative 0.0067 0.0647 1
Giardia lamblia Prolyl-tRNA synthetase 0.0066 0.0633 1
Entamoeba histolytica protein kinase, putative 0.0067 0.0647 1
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0152 0.0276
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.01 0.0301
Giardia lamblia Lysyl-tRNA synthetase 0.0049 0.045 0.7117
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0067 0.0648 0.0977
Brugia malayi hypothetical protein 0.0031 0.0254 0.1001
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.01 0.1334
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.1503 0.4515
Plasmodium falciparum glutathione reductase 0.0057 0.0536 0.0536
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0054 0.0097
Onchocerca volvulus 0.0022 0.0152 0.0592
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0206 0.2145 0.8452
Echinococcus multilocularis geminin 0.0174 0.1796 0.3258
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0054 0.0295
Chlamydia trachomatis threonine--tRNA ligase 0.0012 0.0054 0.1193
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.045 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus multilocularis neuropeptide s receptor 0.0519 0.5514 1
Echinococcus granulosus calcium dependent protein kinase 0.0063 0.0602 0.1092
Brugia malayi G-protein coupled receptor 0.0022 0.0152 0.06
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.01 0.0151
Plasmodium falciparum proline--tRNA ligase 0.0077 0.0751 0.0751
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0234 0.0424
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0048 0.0201
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.0152 0.06
Echinococcus multilocularis solute carrier family 22 0.0031 0.0254 0.0461
Schistosoma mansoni histamine h1 receptor 0.0022 0.0152 0.0458
Schistosoma mansoni protein kinase 0.0067 0.0647 0.1945
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0077 0.0751 0.1132
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0071 0.0254
Loa Loa (eye worm) RecQ helicase 0.0021 0.0144 0.0434
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Onchocerca volvulus 0.0031 0.0254 0.1015
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.0152 0.0276
Echinococcus multilocularis solute carrier family 22 0.0031 0.0254 0.0461
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Onchocerca volvulus 0.0022 0.0152 0.0592
Schistosoma mansoni myosin xvIII 0.0022 0.0152 0.0458
Schistosoma mansoni hypothetical protein 0.0022 0.0152 0.0458
Onchocerca volvulus 0.0031 0.0254 0.1015
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0155 0.0466
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0134 0.1779
Schistosoma mansoni neuropeptide receptor 0.0022 0.0152 0.0458
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0007 0 0.0008
Plasmodium vivax hexose transporter 0.022 0.2295 0.2295
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0134 0.0201
Brugia malayi latrophilin 2 splice variant baaae 0.0141 0.1441 0.5678
Brugia malayi hypothetical protein 0.0022 0.0152 0.06
Schistosoma mansoni protein kinase 0.0067 0.0647 0.1945
Leishmania major hypothetical protein, conserved 0.0011 0.0038 0.0508
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2295 0.4162
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0012 0.0048 0.1073
Echinococcus granulosus synaptic vesicle 2 protein 0.0031 0.0254 0.0461
Schistosoma mansoni ran 0.0022 0.0155 0.0466
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0254 0.1054
Brugia malayi hypothetical protein 0.0008 0.001 0.0041
Schistosoma mansoni amine GPCR 0.0022 0.0152 0.0458
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0624 0.1132
Plasmodium vivax replication factor C subunit 1, putative 0.0012 0.0048 0.0048
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.002 0.0134 0.1779
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.004 0.0532
Brugia malayi Importin beta-1 subunit 0.003 0.0239 0.0943
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0624 0.1132
Brugia malayi Dopamine receptor protein 1 0.0022 0.0152 0.06
Echinococcus multilocularis allatostatin A receptor 0.0022 0.0152 0.0276
Brugia malayi hypothetical protein 0.0031 0.0254 0.1001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0152 0.0276
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.045 0.1353
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0239 0.3188
Toxoplasma gondii sugar transporter ST2 0.0031 0.0254 0.0383
Brugia malayi hypothetical protein 0.0022 0.0152 0.06
Plasmodium vivax importin-beta 2, putative 0.003 0.0239 0.0239
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.045 0.1353
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0179 0.0743
Brugia malayi major facilitator superfamily protein 0.0031 0.0254 0.1001
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0054 0.0097
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.1174
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0053 0.022
Plasmodium falciparum mitogen-activated protein kinase 2 0.0356 0.3758 0.3758
Brugia malayi Pax transcription activation domain interacting protein 0.0012 0.0048 0.019
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.0152 0.0458
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.0098 0.1311
Schistosoma mansoni hypothetical protein 0.0065 0.0624 0.1875
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.0098 0.1311
Loa Loa (eye worm) hypothetical protein 0.0054 0.0499 0.1499
Leishmania major glucose transporter, lmgt2 0.0068 0.0657 0.8747
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0254 0.1001
Echinococcus granulosus neuropeptide receptor A26 0.0519 0.5514 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0053 0.022
Entamoeba histolytica Ran family GTPase 0.0022 0.0155 0.2395
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.0152 0.0276
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0071 0.0129
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0254 0.1054
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0657 0.2725
Plasmodium falciparum glutathione reductase 0.002 0.0134 0.0134
Toxoplasma gondii sugar transporter ST3 0.0031 0.0254 0.0383
Brugia malayi hypothetical protein 0.0022 0.0152 0.06
Schistosoma mansoni amine GPCR 0.0022 0.0152 0.0458
Mycobacterium ulcerans hydrolase 0.0008 0.001 0.0229
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0007 0 0.0001
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0066 0.0633 0.1901
Chlamydia trachomatis histidine--tRNA ligase 0.0007 0 0.0008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Schistosoma mansoni biogenic amine receptor 0.0022 0.0152 0.0458
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0152 0.0276
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0134 0.1779
Mycobacterium leprae Possible regulatory protein 0.0012 0.0053 0.0103
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0152 0.0276
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0077 0.0751 1
Toxoplasma gondii sugar transporter ST1 0.0031 0.0254 0.0383
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Trichomonas vaginalis glutathione reductase, putative 0.002 0.0134 0.0554
Entamoeba histolytica hypothetical protein 0.0012 0.0048 0.0747
Echinococcus granulosus g-protein coupled receptor 0.0022 0.0152 0.0276
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0234 0.0703
Schistosoma mansoni biogenic amine receptor 0.0022 0.0152 0.0458
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0134 0.2966
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Schistosoma mansoni threonyl-tRNA synthetase 0.0007 0 0.0001
Echinococcus granulosus neuropeptide receptor 0.0022 0.0152 0.0276
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0657 0.2725
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0048 0.0201
Onchocerca volvulus 0.0022 0.0152 0.0592
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0536 0.161
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.01 0.0301
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.045 1
Trichomonas vaginalis adenylate cyclase, putative 0.0012 0.0053 0.022
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0657 0.2725
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0134 0.0242
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.0152 0.0458
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.01 0.01
Brugia malayi Melatonin receptor type 1A 0.0022 0.0152 0.06
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Plasmodium vivax glycine--tRNA ligase, putative 0.0012 0.0054 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0048 0.0201
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0022 0.0152 0.0458
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.0152 0.0458
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0155 0.2065
Echinococcus granulosus Sugar transporter ERD6 protein 0.0031 0.0254 0.0461
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0536 0.0972
Trypanosoma cruzi histidyl-tRNA synthetase 0.0007 0 0.0005
Schistosoma mansoni neuropeptide receptor 0.0022 0.0152 0.0458
Schistosoma mansoni hypothetical protein 0.0065 0.0624 0.1875
Mycobacterium ulcerans sugar transporter 0.0031 0.0254 0.5643
Loa Loa (eye worm) hypothetical protein 0.0049 0.045 0.1353
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0134 0.1779
Onchocerca volvulus 0.0022 0.0152 0.0592
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0299 0.0541
Leishmania major protein kinase, putative 0.0017 0.0098 0.1311
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0013 0.0038
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.1174
Schistosoma mansoni hypothetical protein 0.0024 0.0174 0.0523
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0155 0.0281
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0134 0.0201
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.0054 0.0161
Brugia malayi glycyl-tRNA synthetase 0.0012 0.0054 0.0212
Echinococcus granulosus geminin 0.0174 0.1796 0.3258
Onchocerca volvulus 0.0022 0.0152 0.0592
Echinococcus multilocularis calcium dependent protein kinase 0.0063 0.0602 0.1092
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0013 0.0023
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0486 0.648
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0239 0.0361
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0152 0.0276
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0066 0.0633 0.2492
Loa Loa (eye worm) hypothetical protein 0.0012 0.0048 0.0145
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0486 0.0486
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.1325 0.8935
Onchocerca volvulus 0.0022 0.0152 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.001 0.0043
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.0152 0.0276
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0042 0.037 0.2446
Loa Loa (eye worm) hypothetical protein 0.0012 0.0048 0.0145
Plasmodium vivax glutathione reductase, putative 0.0057 0.0536 0.0536
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0152 0.0458
Brugia malayi lysyl-tRNA synthetase 0.0049 0.045 0.1774
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.022 0.2295 0.4162
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0152 0.0276
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0299 0.1176
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0152 0.0276
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0316 0.3328 1
Trypanosoma cruzi glucose transporter, putative 0.0031 0.0254 0.3384
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0536 0.0536
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0071 0.0214
Plasmodium vivax CDK-related protein kinase 6, putative 0.0935 1 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0152 0.0458
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0174 0.0316
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0054 0.0715
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0152 0.0276
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0152 0.0458
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.1174
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.004 0.0532
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0012 0.0048 0.019
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.0013 0.0013
Echinococcus granulosus histidyl tRNA synthetase 0.0007 0 0.0001
Plasmodium vivax threonine--tRNA ligase, putative 0.0012 0.0054 0.0054
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Echinococcus multilocularis solute carrier family 22 0.0031 0.0254 0.0461
Onchocerca volvulus 0.0031 0.0254 0.1015
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0152 0.0458
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Giardia lamblia Sugar-proton symporter 0.0031 0.0254 0.4016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0152 0.0458
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0048 0.0201
Brugia malayi Sulfatase family protein 0.0008 0.001 0.0041
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.01 0.0182
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0152 0.0276
Echinococcus multilocularis orexin receptor type 2 0.0022 0.0152 0.0276
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0066 0.0633 0.1147
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0152 0.0276
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.1054
Echinococcus granulosus lysyl tRNA synthetase 0.0049 0.045 0.0817
Loa Loa (eye worm) hypothetical protein 0.0012 0.0048 0.0145
Echinococcus multilocularis sodium channel protein 0.0038 0.0333 0.0604
Brugia malayi hypothetical protein 0.0022 0.0152 0.06
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0053 0.022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Schistosoma mansoni hypothetical protein 0.0065 0.0624 0.1875
Onchocerca volvulus 0.0022 0.0152 0.0592
Echinococcus granulosus survival motor neuron protein 1 0.0243 0.2538 0.4603
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0763
Trypanosoma brucei trypanothione reductase 0.0057 0.0536 0.714
Brugia malayi isocitrate dehydrogenase 0.0017 0.01 0.0395
Brugia malayi neuropeptide F receptor 0.0022 0.0152 0.06
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.0152 0.0458
Brugia malayi hypothetical protein 0.0034 0.0286 0.1126
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.01 0.0182
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0077 0.0751 1
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0007 0 0.0005
Brugia malayi Isocitrate dehydrogenase 0.0017 0.01 0.0395
Mycobacterium ulcerans sulfatase 0.0008 0.001 0.0229
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0134 0.1779
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0155 0.2451
Echinococcus granulosus solute carrier family 22 0.0031 0.0254 0.0461
Toxoplasma gondii transporter, major facilitator family protein 0.0031 0.0254 0.0383

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 67.482 uM PubChem BioAssay. Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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