Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0257 | 0.0103 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.2278 | 0.5572 | 1 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0217 | 0.0464 | 0.0271 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.0538 | 0.1261 | 1 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.2144 | 0.5242 | 0.6547 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0538 | 0.1261 | 0.1319 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0329 | 0.0742 | 0.0637 |
Mycobacterium leprae | PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 | 0.0329 | 0.0742 | 0.0637 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0307 | 0.0689 | 0.4269 |
Loa Loa (eye worm) | fatty acid synthase | 0.2116 | 0.5171 | 0.5759 |
Chlamydia trachomatis | acyl carrier protein | 0.0217 | 0.0464 | 0.2016 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0217 | 0.0464 | 0.0271 |
Toxoplasma gondii | type I fatty acid synthase | 0.0329 | 0.0742 | 0.1242 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.2144 | 0.5242 | 0.6547 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.1391 | 0.3375 | 0.6016 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0867 | 0.2076 | 0.2389 |
Plasmodium vivax | acyl carrier protein, putative | 0.0217 | 0.0464 | 0.2016 |
Mycobacterium ulcerans | hypothetical protein | 0.0217 | 0.0464 | 0.0271 |
Leishmania major | acyl carrier protein, putative | 0.0217 | 0.0464 | 0.1626 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.2003 | 0.4892 | 0.5439 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.2278 | 0.5572 | 0.6981 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0646 | 0.1528 | 1 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.0538 | 0.1261 | 0.2183 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.1725 | 0.4203 | 0.5183 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0217 | 0.0464 | 0.0271 |
Mycobacterium leprae | Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0217 | 0.0464 | 0.0271 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0304 | 0.0681 | 0.5398 |
Loa Loa (eye worm) | acyl carrier protein | 0.0217 | 0.0464 | 0.0341 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.1219 | 0.2948 | 0.3535 |
Brugia malayi | MH2 domain containing protein | 0.0115 | 0.0213 | 0.0047 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0674 | 0.1597 | 0.1759 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks4 | 0.0329 | 0.0742 | 0.0637 |
Onchocerca volvulus | 0.2003 | 0.4892 | 0.5075 | |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.0538 | 0.1261 | 0.1319 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.0263 | 0.011 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0097 | 0.0167 | 0.1096 |
Echinococcus granulosus | acyl carrier protein mitochondrial | 0.0217 | 0.0464 | 0.368 |
Mycobacterium ulcerans | acyl carrier protein | 0.0217 | 0.0464 | 0.0271 |
Onchocerca volvulus | 0.0133 | 0.0257 | 0.0128 | |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.2278 | 0.5572 | 0.6981 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase | 0.0217 | 0.0464 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.0742 | 0.0662 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.0742 | 0.0662 |
Mycobacterium tuberculosis | Probable acyl carrier protein AcpA (ACP) | 0.0217 | 0.0464 | 0.0271 |
Treponema pallidum | acyl carrier protein | 0.0217 | 0.0464 | 0.5 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0217 | 0.0464 | 0.0271 |
Echinococcus multilocularis | Acyl carrier protein, mitochondrial | 0.0217 | 0.0464 | 0.368 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0737 | 0.1754 | 0.1966 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.2278 | 0.5572 | 0.6981 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0217 | 0.0464 | 0.0271 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.3205 | 0.787 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase FadD9 | 0.0217 | 0.0464 | 0.0271 |
Mycobacterium ulcerans | acyl carrier protein | 0.0217 | 0.0464 | 0.0271 |
Onchocerca volvulus | 0.0097 | 0.0167 | 0.0032 | |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.2278 | 0.5572 | 0.6981 |
Schistosoma mansoni | hypothetical protein | 0.0395 | 0.0907 | 0.5937 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0115 | 0.0213 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.0217 | 0.0464 | 0.3037 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.0538 | 0.1261 | 1 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0646 | 0.1528 | 0.1669 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.1754 | 0.4273 | 0.5275 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.0538 | 0.1261 | 1 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.1725 | 0.4203 | 0.5183 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0217 | 0.0464 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0257 | 0.0103 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.0073 | 0.0479 |
Mycobacterium ulcerans | polyketide synthase | 0.2144 | 0.5242 | 0.6547 |
Trypanosoma cruzi | acyl transferase-like protein, putative | 0.0135 | 0.0263 | 0.0053 |
Mycobacterium tuberculosis | Meromycolate extension acyl carrier protein AcpM | 0.0217 | 0.0464 | 0.0271 |
Brugia malayi | Alcohol dehydrogenase class III | 0.0133 | 0.0257 | 0.0091 |
Plasmodium falciparum | acyl carrier protein | 0.0217 | 0.0464 | 0.2016 |
Trypanosoma cruzi | Acyl carrier protein, mitochondrial, putative | 0.0217 | 0.0464 | 0.2059 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.1526 | 0.371 | 0.6624 |
Mycobacterium ulcerans | malonyl CoA-acyl carrier protein transacylase FabD | 0.0135 | 0.0263 | 0.0007 |
Mycobacterium tuberculosis | Acyl carrier protein (ACP) MbtL | 0.0217 | 0.0464 | 0.0271 |
Loa Loa (eye worm) | alcohol dehydrogenase class III | 0.0133 | 0.0257 | 0.0103 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0538 | 0.1261 | 1 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.2144 | 0.5242 | 0.6547 |
Wolbachia endosymbiont of Brugia malayi | ACP S-malonyltransferase | 0.0135 | 0.0263 | 0.0053 |
Brugia malayi | AMP-binding enzyme family protein | 0.0659 | 0.1561 | 0.1417 |
Echinococcus granulosus | mitochondrial trans 2 enoyl coenzyme A reductase | 0.0133 | 0.0257 | 0.2041 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0646 | 0.1528 | 0.1384 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0133 | 0.0257 | 0.0091 |
Mycobacterium leprae | PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) | 0.0674 | 0.1597 | 0.1759 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0217 | 0.0464 | 0.0271 |
Mycobacterium ulcerans | thioesterase | 0.1787 | 0.4356 | 0.5384 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.2144 | 0.5242 | 0.6547 |
Schistosoma mansoni | methyltransferase-related | 0.0646 | 0.1528 | 1 |
Trypanosoma brucei | Acyl carrier protein, mitochondrial | 0.0217 | 0.0464 | 0.2059 |
Onchocerca volvulus | 0.0217 | 0.0464 | 0.0349 | |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.2144 | 0.5242 | 0.6547 |
Brugia malayi | ADP-specific Phosphofructokinase/Glucokinase conserved region family protein | 0.0135 | 0.0263 | 0.0097 |
Onchocerca volvulus | 0.0133 | 0.0257 | 0.0128 | |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.0659 | 0.1561 | 0.1713 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.0524 | 0.1226 | 0.1272 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.1418 | 0.3441 | 0.4183 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.2079 | 0.5079 | 0.6333 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0538 | 0.1261 | 0.1112 |
Brugia malayi | acyl carrier protein, mitochondrial precursor, putative | 0.0217 | 0.0464 | 0.0302 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.2144 | 0.5242 | 0.6547 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.2003 | 0.4892 | 0.6089 |
Trypanosoma cruzi | acyl transferase-like protein | 0.0135 | 0.0263 | 0.0053 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.1418 | 0.3441 | 0.4183 |
Schistosoma mansoni | alcohol dehydrogenase | 0.0133 | 0.0257 | 0.1684 |
Giardia lamblia | Methyltransferase like 2 | 0.0646 | 0.1528 | 0.5 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0538 | 0.1261 | 0.1319 |
Loa Loa (eye worm) | hypothetical protein | 0.1201 | 0.2905 | 0.3151 |
Mycobacterium leprae | conserved hypothetical protein | 0.0217 | 0.0464 | 0.0271 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.0538 | 0.1261 | 1 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.0538 | 0.1261 | 0.8253 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.3865 | 0.9507 | 1 |
Schistosoma mansoni | acyl carrier protein | 0.0217 | 0.0464 | 0.3037 |
Plasmodium vivax | hypothetical protein, conserved | 0.0307 | 0.0689 | 0.4269 |
Leishmania major | hypothetical protein, conserved | 0.0135 | 0.0263 | 0.0042 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.1418 | 0.3441 | 0.4183 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.3205 | 0.787 | 1 |
Toxoplasma gondii | acyl transferase domain-containing protein | 0.0135 | 0.0263 | 0.0372 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.2278 | 0.5572 | 0.6981 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.2144 | 0.5242 | 0.6547 |
Brugia malayi | Phosphopantetheine attachment site family protein | 0.0217 | 0.0464 | 0.0302 |
Toxoplasma gondii | quinone oxidoreductase, putative | 0.0133 | 0.0257 | 0.0362 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.2144 | 0.5242 | 0.5161 |
Mycobacterium ulcerans | polyketide synthase | 0.2278 | 0.5572 | 0.6981 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0217 | 0.0464 | 0.0271 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0659 | 0.1561 | 0.1713 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.1084 | 0.2613 | 0.4634 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0097 | 0.0167 | 0.1096 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.2144 | 0.5242 | 0.6547 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks3 | 0.0329 | 0.0742 | 0.0637 |
Echinococcus granulosus | Malonyl coenzyme A acyl carrier protein transacylase | 0.0135 | 0.0263 | 0.2083 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0217 | 0.0464 | 0.0271 |
Wolbachia endosymbiont of Brugia malayi | acyl carrier protein | 0.0217 | 0.0464 | 0.2059 |
Trypanosoma brucei | acyl transferase-like protein | 0.0135 | 0.0263 | 0.0053 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0217 | 0.0464 | 0.0271 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.0538 | 0.1261 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0115 | 0.0213 | 0.0053 |
Schistosoma mansoni | [ACP] S-malonyltransferase | 0.0135 | 0.0263 | 0.1719 |
Echinococcus multilocularis | mitochondrial trans 2 enoyl coenzyme A reductase | 0.0133 | 0.0257 | 0.2041 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.3205 | 0.787 | 1 |
Echinococcus granulosus | NADH dehydrogenase | 0.0217 | 0.0464 | 0.368 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0217 | 0.0464 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.2003 | 0.4892 | 0.4805 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.2144 | 0.5242 | 0.6547 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0674 | 0.1597 | 0.1759 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0538 | 0.1261 | 1 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.2079 | 0.5079 | 0.6333 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.2278 | 0.5572 | 0.6981 |
Schistosoma mansoni | [ACP] S-malonyltransferase | 0.0135 | 0.0263 | 0.1719 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0538 | 0.1261 | 1 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0133 | 0.0257 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0257 | 0.0103 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.1787 | 0.4356 | 0.5384 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.1787 | 0.4356 | 0.5384 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.154 | 0.3745 | 0.4581 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0304 | 0.0681 | 0.5398 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0257 | 0.0103 |
Echinococcus multilocularis | NADH dehydrogenase | 0.0217 | 0.0464 | 0.368 |
Echinococcus granulosus | dnaJ subfamily B | 0.0395 | 0.0907 | 0.7194 |
Mycobacterium tuberculosis | Conserved protein | 0.0646 | 0.1528 | 0.1669 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0217 | 0.0464 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0217 | 0.0464 | 0.0271 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.2278 | 0.5572 | 0.6981 |
Toxoplasma gondii | acyl carrier protein ACP | 0.0217 | 0.0464 | 0.0737 |
Schistosoma mansoni | [ACP] S-malonyltransferase | 0.0135 | 0.0263 | 0.1719 |
Loa Loa (eye worm) | hypothetical protein | 0.3602 | 0.8855 | 1 |
Echinococcus multilocularis | AMP dependent ligase | 0.0217 | 0.0464 | 0.368 |
Loa Loa (eye worm) | acyl carrier protein | 0.0986 | 0.2371 | 0.2536 |
Echinococcus granulosus | AMP dependent ligase | 0.0217 | 0.0464 | 0.368 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.2278 | 0.5572 | 0.6981 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.3205 | 0.787 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0646 | 0.1528 | 1 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.0538 | 0.1261 | 0.1259 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.1725 | 0.4203 | 0.5183 |
Mycobacterium ulcerans | thioesterase TesA | 0.1787 | 0.4356 | 0.5384 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.0538 | 0.1261 | 1 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0133 | 0.0257 | 0.0091 |
Loa Loa (eye worm) | phosphopantetheine attachment site family protein | 0.0217 | 0.0464 | 0.0341 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.0538 | 0.1261 | 0.7899 |
Onchocerca volvulus | 0.3732 | 0.9177 | 0.9648 | |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0329 | 0.0742 | 0.0637 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0395 | 0.0907 | 0.7194 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0217 | 0.0464 | 0.0302 |
Schistosoma mansoni | zinc binding dehydrogenase | 0.0133 | 0.0257 | 0.1684 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0217 | 0.0464 | 0.0271 |
Onchocerca volvulus | Acyl carrier protein, mitochondrial homolog | 0.0217 | 0.0464 | 0.0349 |
Onchocerca volvulus | Putative alcohol dehydrogenase | 0.0133 | 0.0257 | 0.0128 |
Echinococcus multilocularis | Malonyl coenzyme A acyl carrier protein transacylase | 0.0135 | 0.0263 | 0.2083 |
Toxoplasma gondii | Zn-containing alcohol dehydrogenase | 0.0133 | 0.0257 | 0.0362 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.074 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.073 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.