Detailed information for compound 1697907

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 2255.87 | Formula: C42H70O77S14
  • H donors: 21 H acceptors: 49 LogP: -20.39 Rotable bonds: 35
    Rule of 5 violations (Lipinski): 4
  • SMILES: O[C@@H]1C2O[C@@H]3[C@H](COS(=O)(=O)O)O[C@@H]([C@H]([C@H]3OS(=O)(=O)O)O)O[C@@H]3[C@H](COS(=O)(=O)O)O[C@@H]([C@H]([C@H]3OS(=O)(=O)O)O)O[C@@H]3[C@H](COS(=O)(=O)O)O[C@@H]([C@H]([C@H]3OS(=O)(=O)O)O)O[C@@H]3[C@@H](O[C@H](O[C@@H]4[C@@H](O[C@H](O[C@@H]5[C@@H](OC(O[C@@H]([C@@H]1OS(=O)(=O)O)[C@@H](O2)COS(=O)(=O)O)[C@@H](O)[C@H]5OS(=O)(=O)O)COS(=O)(=O)O)[C@@H](O)[C@H]4OS(=O)(=O)O)COS(=O)(=O)O)[C@@H](O)[C@H]3OS(=O)(=O)O)COS(=O)(=O)O
  • InChi: 1S/C42H70O77S14/c43-15-29(113-127(71,72)73)22-8(1-92-120(50,51)52)99-36(15)107-23-9(2-93-121(53,54)55)101-38(17(45)31(23)115-129(77,78)79)109-25-11(4-95-123(59,60)61)103-40(19(47)33(25)117-131(83,84)85)111-27-13(6-97-125(65,66)67)105-42(21(49)35(27)119-133(89,90)91)112-28-14(7-98-126(68,69)70)104-41(20(48)34(28)118-132(86,87)88)110-26-12(5-96-124(62,63)64)102-39(18(46)32(26)116-130(80,81)82)108-24-10(3-94-122(56,57)58)100-37(106-22)16(44)30(24)114-128(74,75)76/h8-49H,1-7H2,(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)(H,77,78,79)(H,80,81,82)(H,83,84,85)(H,86,87,88)(H,89,90,91)/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22+,23+,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34+,35+,36+,37+,38+,39+,40+,41?,42?/m0/s1
  • InChiKey: MHVFCILSXAGBOS-VXBPJIFPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Echinococcus multilocularis SH2 domain containing protein 7 0.0107 0.0683 0.063
Leishmania major cathepsin L-like protease 0.0234 0.1903 1
Schistosoma mansoni Dab2-interacting protein-like 0.0105 0.0657 0.0657
Schistosoma mansoni cathepsin s 0.0073 0.0355 0.0355
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0212 0.1691 0.1691
Plasmodium vivax unspecified product 0.0127 0.0867 0.4054
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0053 0.0161 0.0161
Echinococcus granulosus cathepsin b 0.0451 0.3991 0.3957
Schistosoma mansoni hypothetical protein 0.0105 0.0657 0.0657
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Echinococcus granulosus expressed conserved protein 0.0107 0.0683 0.063
Entamoeba histolytica cysteine proteinase, putative 0.0127 0.0867 0.0906
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0161 0.1197 0.2704
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0657 0.2846
Echinococcus granulosus tyrosine protein kinase Blk 0.0971 0.8992 0.8986
Toxoplasma gondii cathepsin B 0.0176 0.1346 0.68
Leishmania major cathepsin L-like protease 0.0234 0.1903 1
Entamoeba histolytica protein kinase, putative 0.0107 0.0683 0.0669
Loa Loa (eye worm) hypothetical protein 0.0161 0.1197 0.1147
Schistosoma mansoni serine/threonine protein kinase 0.0136 0.0956 0.0956
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0053 0.0161 0.0161
Echinococcus multilocularis tensin 0.0107 0.0683 0.063
Onchocerca volvulus 0.0139 0.0981 0.4708
Entamoeba histolytica hypothetical protein 0.0105 0.0657 0.0636
Schistosoma mansoni tensin-related 0.0107 0.0683 0.0683
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0107 0.0683 0.063
Leishmania major cathepsin L-like protease 0.0234 0.1903 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0234 0.1903 0.1857
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0355 0.0505
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0127 0.0867 0.0867
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Brugia malayi SH2 domain containing protein 0.0107 0.0683 0.063
Echinococcus multilocularis tyrosine protein kinase Abl 0.0243 0.199 0.1944
Echinococcus granulosus hypothetical protein 0.0107 0.0683 0.063
Loa Loa (eye worm) hypothetical protein 0.0105 0.0657 0.0604
Entamoeba histolytica cysteine proteinase 1, putative 0.0127 0.0867 0.0906
Echinococcus multilocularis transfer RNA-Ala 0.0105 0.0657 0.0604
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0105 0.0657 0.0604
Brugia malayi SH2 domain containing protein 0.0107 0.0683 0.063
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0657 0.1294
Echinococcus granulosus tyrosine protein kinase Src42A 0.094 0.8693 0.8686
Echinococcus granulosus growth factor receptor bound protein 2 0.0212 0.1691 0.1644
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0107 0.0683 0.063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Loa Loa (eye worm) guanylate kinase 0.0105 0.0657 0.0604
Echinococcus granulosus tyrosine protein kinase Fyn 0.1076 1 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Brugia malayi SH2 domain containing protein 0.0107 0.0683 0.063
Echinococcus multilocularis cysteine protease 0.0234 0.1903 0.1857
Brugia malayi SH2 domain containing protein 0.0107 0.0683 0.063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0234 0.1903 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0107 0.0683 0.063
Onchocerca volvulus 0.0234 0.1903 1
Echinococcus multilocularis 0.0107 0.0683 0.063
Onchocerca volvulus 0.0139 0.0981 0.4708
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1076 1 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0234 0.1903 1
Brugia malayi hypothetical protein 0.0107 0.0683 0.063
Echinococcus multilocularis SHC transforming protein 3 0.0107 0.0683 0.063
Brugia malayi Variant SH3 domain containing protein 0.0212 0.1691 0.1644
Onchocerca volvulus 0.0105 0.0657 0.2846
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0057 0.0057
Echinococcus granulosus tyrosine protein kinase Src64B 0.1076 1 1
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0107 0.0683 0.0683
Schistosoma mansoni voltage-gated potassium channel 0.016 0.1186 0.1186
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0176 0.1346 0.68
Onchocerca volvulus 0.0139 0.0981 0.4708
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0161 0.1197 0.5946
Entamoeba histolytica cysteine proteinase, putative 0.0127 0.0867 0.0906
Brugia malayi cytokine inducible SH2-containing protein 5 0.0107 0.0683 0.063
Trypanosoma cruzi cysteine protease, putative 0.0127 0.0867 0.1844
Loa Loa (eye worm) TK/FER protein kinase 0.0139 0.0981 0.093
Loa Loa (eye worm) TK/FER protein kinase 0.0139 0.0981 0.093
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0212 0.1691 0.1644
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0234 0.1903 0.1857
Schistosoma mansoni cathepsin C 0.0053 0.0161 0.0161
Brugia malayi Cathepsin L-like precursor 0.0234 0.1903 0.1857
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0105 0.0657 0.0604
Loa Loa (eye worm) TK protein kinase 0.0864 0.7958 0.7946
Echinococcus granulosus tyrosine protein kinase Src42A 0.1076 1 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.0657 0.0604
Echinococcus multilocularis cathepsin L cysteine protease 0.0234 0.1903 0.1857
Trypanosoma cruzi cysteine peptidase, putative 0.0234 0.1903 0.4548
Echinococcus multilocularis nostrin 0.0105 0.0657 0.0604
Brugia malayi Protein kinase domain containing protein 0.0139 0.0981 0.093
Schistosoma mansoni vav2 0.0107 0.0683 0.0683
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0234 0.1903 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0053 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Echinococcus granulosus SH2 motif 0.0107 0.0683 0.063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0867 0.1688
Brugia malayi STAT protein, DNA binding domain containing protein 0.0107 0.0683 0.063
Entamoeba histolytica cysteine proteinase, putative 0.0127 0.0867 0.0906
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0139 0.0981 0.093
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0105 0.0657 0.0604
Trypanosoma cruzi cysteine peptidase, putative 0.0234 0.1903 0.4548
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0657 0.2846
Entamoeba histolytica cysteine proteinase, putative 0.0234 0.1903 0.2234
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0234 0.1903 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0451 0.3991 0.3991
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Brugia malayi Cathepsin L-like precursor 0.0234 0.1903 0.1857
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0146 0.1057 0.1006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0127 0.0867 0.4054
Echinococcus multilocularis cathepsin b 0.0451 0.3991 0.3957
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0053 0.0161 0.0105
Trypanosoma cruzi cysteine peptidase, putative 0.0234 0.1903 0.4548
Echinococcus granulosus tyrosine protein kinase Fyn 0.1076 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0234 0.1903 1
Loa Loa (eye worm) TK/FER protein kinase 0.0139 0.0981 0.093
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0107 0.0683 0.063
Entamoeba histolytica hypothetical protein, conserved 0.0105 0.0657 0.0636
Echinococcus multilocularis tyrosine protein kinase Blk 0.0971 0.8992 0.8986
Onchocerca volvulus 0.0105 0.0657 0.2846
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0176 0.1346 0.1346
Brugia malayi Papain family cysteine protease containing protein 0.0127 0.0867 0.0815
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Schistosoma mansoni tensin 0.0107 0.0683 0.0683
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1076 1 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0053 0.0161 0.0105
Echinococcus granulosus tyrosine protein kinase Lyn 0.1076 1 1
Onchocerca volvulus 0.0139 0.0981 0.4708
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0127 0.0867 0.4054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0234 0.1903 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0107 0.0683 0.063
Plasmodium falciparum cysteine proteinase falcipain 3 0.0234 0.1903 1
Trypanosoma cruzi cysteine proteinase, putative 0.0127 0.0867 0.1844
Entamoeba histolytica hypothetical protein, conserved 0.0105 0.0657 0.0636
Echinococcus multilocularis intersectin 2 0.0105 0.0657 0.0604
Leishmania major cathepsin L-like protease 0.0234 0.1903 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0451 0.3991 0.3991
Trypanosoma cruzi cruzipain precursor, putative 0.0234 0.1903 0.4548
Plasmodium vivax vivapain-3 0.0127 0.0867 0.4054
Trypanosoma cruzi cysteine proteinase, putative 0.0127 0.0867 0.1844
Schistosoma mansoni cathepsin F (C01 family) 0.0234 0.1903 0.1903
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1076 1 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0105 0.0657 0.0604
Loa Loa (eye worm) TK/FER protein kinase 0.0139 0.0981 0.093
Brugia malayi protein-tyrosine kinase 0.0971 0.8992 0.8986
Onchocerca volvulus 0.0107 0.0683 0.2993
Echinococcus granulosus SHC transforming protein 3 0.0107 0.0683 0.063
Echinococcus granulosus suppressor of cytokine signaling 6 0.0107 0.0683 0.063
Schistosoma mansoni cathepsin S (C01 family) 0.0053 0.0161 0.0161
Brugia malayi Cathepsin L-like precursor 0.0234 0.1903 0.1857
Schistosoma mansoni run and tbc1 domain containing 0.0105 0.0657 0.0657
Loa Loa (eye worm) ctsf protein 0.0234 0.1903 0.1857
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0107 0.0683 0.0683
Schistosoma mansoni tensin 0.0107 0.0683 0.0683
Schistosoma mansoni signal transduction protein lnk-related 0.0107 0.0683 0.0683
Onchocerca volvulus 0.0105 0.0657 0.2846
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0057 0.0057
Echinococcus multilocularis growth factor receptor bound protein 2 0.0212 0.1691 0.1644
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Giardia lamblia Cathepsin B precursor 0.0176 0.1346 1
Brugia malayi Sex muscle abnormal protein 5 0.0212 0.1691 0.1644
Echinococcus granulosus cysteine protease 0.0127 0.0867 0.0815
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0139 0.0981 0.093
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0105 0.0657 0.0604
Echinococcus granulosus cathepsin l1 0.0161 0.1197 0.1147
Brugia malayi Papain family cysteine protease containing protein 0.0053 0.0161 0.0105
Brugia malayi Fes/CIP4 homology domain containing protein 0.0105 0.0657 0.0604
Schistosoma mansoni suppressor of cytokine signaling 0.0107 0.0683 0.0683
Entamoeba histolytica unconventional myosin IB 0.0105 0.0657 0.0636
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Loa Loa (eye worm) protein-tyrosine kinase 0.0105 0.0657 0.0604
Echinococcus granulosus endophilin A3 0.0105 0.0657 0.0604
Trichomonas vaginalis p67phox protein, putative 0.0105 0.0657 0.2846
Brugia malayi Papain family cysteine protease containing protein 0.0234 0.1903 0.1857
Brugia malayi SH2 domain containing protein 0.0139 0.0981 0.093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0234 0.1903 1
Onchocerca volvulus 0.0234 0.1903 1
Entamoeba histolytica protein kinase, putative 0.0105 0.0657 0.0636
Onchocerca volvulus Putative cortactin 0.0105 0.0657 0.2846
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Echinococcus granulosus cathepsin L cysteine protease 0.0127 0.0867 0.0815
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0243 0.199 0.1944
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0107 0.0683 0.2993
Brugia malayi Papain family cysteine protease containing protein 0.0127 0.0867 0.0815
Plasmodium vivax vivapain-1 0.0127 0.0867 0.4054
Echinococcus granulosus src region 0.0105 0.0657 0.0604
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Schistosoma mansoni hypothetical protein 0.0107 0.0683 0.0683
Brugia malayi Protein kinase domain containing protein 0.0139 0.0981 0.093
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0657 0.1294
Loa Loa (eye worm) p53BP2 0.0105 0.0657 0.0604
Entamoeba histolytica protein kinase, putative 0.0864 0.7958 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0161 0.0105
Brugia malayi cathepsin L precursor 0.0053 0.0161 0.0105
Schistosoma mansoni SH2A 0.0107 0.0683 0.0683
Schistosoma mansoni dynamin-associated protein 0.0105 0.0657 0.0657
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0053 0.0161 0.0161
Echinococcus granulosus signal transduction protein lnk realted 0.0107 0.0683 0.063
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0107 0.0683 0.0683
Echinococcus multilocularis NCK adaptor protein 0.0212 0.1691 0.1644
Brugia malayi Myosin tail family protein 0.0105 0.0657 0.0604
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1076 1 1
Loa Loa (eye worm) STAT protein 0.0107 0.0683 0.063
Loa Loa (eye worm) TK/FER protein kinase 0.0139 0.0981 0.093
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0146 0.1057 0.1006
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0212 0.1691 0.1644
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0044 0.0068 0.0011
Schistosoma mansoni cell polarity protein 0.0105 0.0657 0.0657
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0127 0.0867 0.1844
Echinococcus granulosus SH2 motif 0.0107 0.0683 0.063
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0107 0.0683 0.063
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0137 0.0964 0.461
Entamoeba histolytica cysteine proteinase, putative 0.0161 0.1197 0.1328
Loa Loa (eye worm) thyroid receptor interactor 0.0105 0.0657 0.0604
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0073 0.0355 0.03
Onchocerca volvulus 0.0107 0.0683 0.2993
Brugia malayi RhoGAP domain containing protein 0.0107 0.0683 0.063
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0105 0.0657 0.0604
Loa Loa (eye worm) SH2 domain-containing protein 0.0107 0.0683 0.063
Echinococcus granulosus N chimaerin 0.0107 0.0683 0.063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0867 0.1688
Echinococcus granulosus tensin 0.0107 0.0683 0.063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0107 0.0683 0.0683
Entamoeba histolytica BAR/SH3 domain containing protein 0.0105 0.0657 0.0636
Echinococcus granulosus suppressor of cytokine signaling 7 0.0107 0.0683 0.063
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0107 0.0683 0.063
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0105 0.0657 0.0604
Brugia malayi Variant SH3 domain containing protein 0.0105 0.0657 0.0604
Schistosoma mansoni C-fyn 0.0105 0.0657 0.0657
Trypanosoma cruzi cruzipain precursor, putative 0.0073 0.0355 0.0505
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0105 0.0657 0.0657
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0161 0.1197 0.5946
Schistosoma mansoni tyrosine kinase 0.0243 0.199 0.199
Loa Loa (eye worm) hypothetical protein 0.0053 0.0161 0.0105
Brugia malayi Immunoglobulin I-set domain containing protein 0.0044 0.0068 0.0011
Brugia malayi cathepsin F-like cysteine proteinase 0.0073 0.0355 0.03
Brugia malayi Variant SH3 domain containing protein 0.0107 0.0683 0.063
Echinococcus granulosus cathepsin L 0.0127 0.0867 0.0815
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0234 0.1903 1
Onchocerca volvulus Cathepsin L homolog 0.0234 0.1903 1
Schistosoma mansoni growth factor receptor-bound protein 0.0212 0.1691 0.1691
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0073 0.0355 0.03
Entamoeba histolytica hypothetical protein 0.0105 0.0657 0.0636
Echinococcus multilocularis tensin 0.0107 0.0683 0.063
Leishmania major cysteine peptidase A (CPA) 0.0234 0.1903 1
Schistosoma mansoni formin binding protein and related proteins 0.0105 0.0657 0.0657
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0176 0.1346 0.3093
Echinococcus granulosus SH2 domain containing adapter protein F 0.0107 0.0683 0.063
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0107 0.0683 0.063
Loa Loa (eye worm) hypothetical protein 0.0105 0.0657 0.0604
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0234 0.1903 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0146 0.1057 0.1006
Onchocerca volvulus 0.0107 0.0683 0.2993
Brugia malayi Protein kinase domain containing protein 0.0139 0.0981 0.093
Brugia malayi Variant SH3 domain containing protein 0.0105 0.0657 0.0604
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1076 1 1
Echinococcus granulosus Spectrin alpha actinin 0.0105 0.0657 0.0604
Leishmania major cathepsin L-like protease 0.0234 0.1903 1
Schistosoma mansoni sorbin 0.0105 0.0657 0.0657
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0107 0.0683 0.2993
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0971 0.8992 0.8986
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0451 0.3991 0.3991
Echinococcus granulosus cathepsin l cysteine peptidase 0.0234 0.1903 0.1857
Brugia malayi Variant SH3 domain containing protein 0.0212 0.1691 0.1644
Loa Loa (eye worm) hypothetical protein 0.0053 0.0161 0.0105
Loa Loa (eye worm) TK/FER protein kinase 0.0139 0.0981 0.093
Trypanosoma cruzi cysteine peptidase, putative 0.0234 0.1903 0.4548
Toxoplasma gondii cathepsin CPL 0.0234 0.1903 1
Schistosoma mansoni suppressor of cytokine signaling 0.0107 0.0683 0.0683
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0053 0.0161 0.0161
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1076 1 1
Brugia malayi Src substrate cortactin 0.0105 0.0657 0.0604
Echinococcus multilocularis cathepsin L 0.0053 0.0161 0.0105
Loa Loa (eye worm) hypothetical protein 0.0105 0.0657 0.0604
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1076 1 1
Loa Loa (eye worm) SH2 domain-containing protein 0.0107 0.0683 0.063
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0451 0.3991 1
Onchocerca volvulus 0.0234 0.1903 1
Echinococcus granulosus tyrosine protein kinase ABL1 0.0139 0.0981 0.093
Brugia malayi Cathepsin L-like precursor 0.0073 0.0355 0.03
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0243 0.199 0.199
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0657 0.2846
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Giardia lamblia Cathepsin B precursor 0.0176 0.1346 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0127 0.0867 0.0867
Echinococcus granulosus cathepsin l1 0.0234 0.1903 0.1857
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0234 0.1903 1
Schistosoma mansoni tyrosine kinase 0.0243 0.199 0.199
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0053 0.0161 0.0161
Echinococcus multilocularis tyrosine protein kinase shark 0.0139 0.0981 0.093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0234 0.1903 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0234 0.1903 0.1857
Loa Loa (eye worm) SRC-1 0.1076 1 1
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0107 0.0683 0.063
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Onchocerca volvulus 0.0139 0.0981 0.4708
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0053 0.0161 0.0161
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0234 0.1903 1
Schistosoma mansoni dreadlocks/dock 0.0105 0.0657 0.0657
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0105 0.0657 0.0604
Brugia malayi Cathepsin L-like precursor 0.0161 0.1197 0.1147
Brugia malayi Peripheral plasma membrane protein CASK 0.0105 0.0657 0.0604
Loa Loa (eye worm) TK/FER protein kinase 0.0139 0.0981 0.093
Brugia malayi SH2 domain containing protein 0.0139 0.0981 0.093
Schistosoma mansoni tyrosine kinase 0.1076 1 1
Onchocerca volvulus 0.0107 0.0683 0.2993
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0234 0.1903 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0176 0.1346 0.5527
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0234 0.1903 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0234 0.1903 1
Schistosoma mansoni tensin 0.0107 0.0683 0.0683
Echinococcus granulosus cathepsin L cysteine proteinase 0.0234 0.1903 0.1857
Brugia malayi hypothetical protein 0.0139 0.0981 0.093
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0105 0.0657 0.0604
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0105 0.0657 0.0604
Leishmania major cathepsin L-like protease 0.0234 0.1903 1
Entamoeba histolytica hypothetical protein 0.0105 0.0657 0.0636
Plasmodium vivax vivapain-2 0.0234 0.1903 1
Onchocerca volvulus 0.0107 0.0683 0.2993
Loa Loa (eye worm) TK protein kinase 0.0971 0.8992 0.8986
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0053 0.0161 0.0161
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Loa Loa (eye worm) TK/ABL protein kinase 0.0139 0.0981 0.093
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0053 0.0161 0.0105
Schistosoma mansoni cathepsin F (C01 family) 0.0161 0.1197 0.1197
Schistosoma mansoni cathepsin B (C01 family) 0.0053 0.0161 0.0161
Schistosoma mansoni growth factor receptor-bound protein 0.0212 0.1691 0.1691
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0234 0.1903 0.1857
Schistosoma mansoni GTPase activating protein 0.0107 0.0683 0.0683
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0234 0.1903 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0107 0.0683 0.063
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Loa Loa (eye worm) hypothetical protein 0.0053 0.0161 0.0105
Schistosoma mansoni tensin-related 0.0107 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0073 0.0355 0.03
Echinococcus granulosus tyrosine protein kinase Fyn 0.1076 1 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0234 0.1903 0.1857
Loa Loa (eye worm) hypothetical protein 0.0105 0.0657 0.0604
Giardia lamblia Cathepsin B precursor 0.0176 0.1346 1
Entamoeba histolytica hypothetical protein 0.0105 0.0657 0.0636
Brugia malayi SH2 domain containing protein 0.0107 0.0683 0.063
Echinococcus multilocularis SH2 motif 0.0107 0.0683 0.063
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0657 0.2846
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0234 0.1903 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0243 0.199 0.1944
Brugia malayi cathepsin F-like cysteine proteinase 0.0053 0.0161 0.0105
Loa Loa (eye worm) SH2 domain-containing protein 0.0107 0.0683 0.063
Brugia malayi cathepsin Z-like cysteine proteinase 0.0053 0.0161 0.0105
Onchocerca volvulus 0.0161 0.1197 0.5946
Brugia malayi Papain family cysteine protease containing protein 0.0053 0.0161 0.0105
Loa Loa (eye worm) hypothetical protein 0.0451 0.3991 0.3957
Onchocerca volvulus 0.0234 0.1903 1
Echinococcus multilocularis expressed protein 0.0105 0.0657 0.0604
Loa Loa (eye worm) hypothetical protein 0.0139 0.0981 0.093
Entamoeba histolytica cysteine proteinase 2 0.0127 0.0867 0.0906
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0053 0.0161 0.0161
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0107 0.0683 0.063
Brugia malayi cathepsin L-like precursor 0.0161 0.1197 0.1147
Echinococcus multilocularis tyrosine protein kinase Src42A 0.094 0.8693 0.8686
Echinococcus granulosus intersectin 2 0.0105 0.0657 0.0604
Brugia malayi Protein kinase domain containing protein 0.0139 0.0981 0.093
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0107 0.0683 0.0669
Brugia malayi Cathepsin L-like precursor 0.0234 0.1903 0.1857
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0107 0.0683 0.063
Schistosoma mansoni apoptosis stimulating of P53 0.0105 0.0657 0.0657
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0137 0.0964 0.461
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0107 0.0683 0.063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0127 0.0867 0.0867
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0139 0.0981 0.093
Loa Loa (eye worm) cysteine protease 0.0234 0.1903 0.1857
Echinococcus granulosus tyrosine protein kinase Srms 0.0139 0.0981 0.093
Echinococcus granulosus c src tyrosine kinase 0.0243 0.199 0.1944
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0451 0.3991 0.3991
Entamoeba histolytica hypothetical protein 0.0105 0.0657 0.0636
Brugia malayi Variant SH3 domain containing protein 0.0105 0.0657 0.0604
Loa Loa (eye worm) TK/FER protein kinase 0.0139 0.0981 0.093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0234 0.1903 1
Echinococcus multilocularis endophilin A3 0.0105 0.0657 0.0604
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0053 0.0161 0.0105
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0234 0.1903 1
Brugia malayi Variant SH3 domain containing protein 0.0105 0.0657 0.0604
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Schistosoma mansoni tyrosine kinase 0.0139 0.0981 0.0981
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0107 0.0683 0.063
Loa Loa (eye worm) hypothetical protein 0.0161 0.1197 0.1147
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0657 0.2846
Echinococcus multilocularis Spectrin alpha actinin 0.0105 0.0657 0.0604
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0234 0.1903 1
Brugia malayi Papain family cysteine protease containing protein 0.0053 0.0161 0.0105
Echinococcus granulosus epidermal growth factor receptor kinase 0.0105 0.0657 0.0604
Loa Loa (eye worm) cathepsin B 0.0176 0.1346 0.1296
Schistosoma mansoni hypothetical protein 0.0105 0.0657 0.0657
Loa Loa (eye worm) hypothetical protein 0.0105 0.0657 0.0604
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Brugia malayi Variant SH3 domain containing protein 0.0105 0.0657 0.0604
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0107 0.0683 0.063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0234 0.1903 1
Leishmania major cathepsin L-like protease 0.0234 0.1903 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0243 0.199 0.1944
Echinococcus granulosus tyrosine kinase 0.0971 0.8992 0.8986
Brugia malayi tRNA modification GTPase TrmE family protein 0.0107 0.0683 0.063
Brugia malayi Spectrin alpha chain 0.0105 0.0657 0.0604
Entamoeba histolytica hypothetical protein 0.0105 0.0657 0.0636
Brugia malayi Variant SH3 domain containing protein 0.0107 0.0683 0.063
Entamoeba histolytica cysteine proteinase, putative 0.0127 0.0867 0.0906
Schistosoma mansoni nck2/grb4 0.0212 0.1691 0.1691
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0105 0.0657 0.0657
Onchocerca volvulus 0.0105 0.0657 0.2846
Brugia malayi SH2 domain containing protein 0.0107 0.0683 0.063
Echinococcus granulosus NCK adaptor protein 0.0212 0.1691 0.1644
Loa Loa (eye worm) hypothetical protein 0.0105 0.0657 0.0604
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0139 0.0981 0.1052
Brugia malayi protein-tyrosine kinase 0.0105 0.0657 0.0604
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Onchocerca volvulus Cathepsin L homolog 0.0234 0.1903 1
Echinococcus multilocularis signal transduction protein lnk realted 0.0107 0.0683 0.063
Schistosoma mansoni voltage-gated potassium channel 0.016 0.1186 0.1186
Schistosoma mansoni sorting nexin 0.0105 0.0657 0.0657
Brugia malayi Cathepsin L-like precursor 0.0161 0.1197 0.1147
Loa Loa (eye worm) hypothetical protein 0.0105 0.0657 0.0604
Loa Loa (eye worm) hypothetical protein 0.0073 0.0355 0.03
Brugia malayi Variant SH3 domain containing protein 0.0105 0.0657 0.0604
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0105 0.0657 0.0604
Brugia malayi Cathepsin L-like precursor 0.0234 0.1903 0.1857
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0234 0.1903 1
Echinococcus granulosus SH2 domain containing protein 7 0.0107 0.0683 0.063
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1076 1 1
Echinococcus granulosus cathepsin b 0.0451 0.3991 0.3957
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0234 0.1903 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Onchocerca volvulus 0.0234 0.1903 1
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0105 0.0657 0.0604
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0107 0.0683 0.063
Echinococcus granulosus tyrosine protein kinase shark 0.0139 0.0981 0.093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0234 0.1903 1
Brugia malayi SH3 domain containing protein 0.0105 0.0657 0.0604
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.0105 0.0657 0.1294
Echinococcus multilocularis tyrosine kinase 0.0139 0.0981 0.093
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.0105 0.0657 0.2846
Echinococcus multilocularis N chimaerin 0.0107 0.0683 0.063
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Loa Loa (eye worm) TK/FER protein kinase 0.0139 0.0981 0.093
Echinococcus granulosus cathepsin L 0.0053 0.0161 0.0105
Plasmodium vivax unspecified product 0.0073 0.0355 0.1111
Brugia malayi cathepsin L-like cysteine proteinase 0.0053 0.0161 0.0105
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Echinococcus multilocularis SH2 motif 0.0107 0.0683 0.063
Loa Loa (eye worm) hypothetical protein 0.0053 0.0161 0.0105
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0105 0.0657 0.0657
Brugia malayi SH2 domain containing protein 0.0107 0.0683 0.063
Loa Loa (eye worm) hypothetical protein 0.0053 0.0161 0.0105
Brugia malayi Tensin 0.0107 0.0683 0.063
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1076 1 1
Entamoeba histolytica cysteine protease, putative 0.0234 0.1903 0.2234
Onchocerca volvulus LIM and SH3 domain protein homolog 0.0105 0.0657 0.2846
Echinococcus multilocularis c src tyrosine kinase 0.0243 0.199 0.1944
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0146 0.1057 0.1006
Brugia malayi Cathepsin L-like precursor 0.0234 0.1903 0.1857
Onchocerca volvulus 0.0139 0.0981 0.4708
Echinococcus granulosus fch and double sh3 domains protein 2 0.0105 0.0657 0.0604
Entamoeba histolytica hypothetical protein 0.0105 0.0657 0.0636
Entamoeba histolytica SH2 domain containing protein 0.0107 0.0683 0.0669
Brugia malayi fibroinase precursor 0.0053 0.0161 0.0105
Schistosoma mansoni shc transforming protein 0.0107 0.0683 0.0683
Schistosoma mansoni hypothetical protein 0.0107 0.0683 0.0683
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Entamoeba histolytica cysteine proteinase, putative 0.0234 0.1903 0.2234
Echinococcus granulosus tyrosine protein kinase HCK 0.0864 0.7958 0.7946
Loa Loa (eye worm) hypothetical protein 0.0234 0.1903 0.1857
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0105 0.0657 0.0604
Onchocerca volvulus 0.0105 0.0657 0.2846
Echinococcus granulosus nostrin 0.0105 0.0657 0.0604
Echinococcus multilocularis cysteine protease 0.0234 0.1903 0.1857
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0107 0.0683 0.063
Onchocerca volvulus 0.0234 0.1903 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0971 0.8992 0.8986
Loa Loa (eye worm) TK/FER protein kinase 0.0139 0.0981 0.093
Loa Loa (eye worm) hypothetical protein 0.0105 0.0657 0.0604
Echinococcus multilocularis cathepsin L 0.0127 0.0867 0.0815
Brugia malayi Guanylate kinase family protein 0.0105 0.0657 0.0604
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0105 0.0657 0.0657
Echinococcus multilocularis tyrosine protein kinase HCK 0.0864 0.7958 0.7946
Loa Loa (eye worm) hypothetical protein 0.0212 0.1691 0.1644
Onchocerca volvulus Cathepsin F homolog 0.0234 0.1903 1
Schistosoma mansoni tyrosine kinase 0.0139 0.0981 0.0981
Schistosoma mansoni eps8-related protein 0.0105 0.0657 0.0657
Plasmodium vivax vivapain-2 0.0234 0.1903 1
Echinococcus granulosus expressed protein 0.0105 0.0657 0.0604
Brugia malayi Cathepsin L-like cysteine proteinase 0.0161 0.1197 0.1147
Loa Loa (eye worm) hypothetical protein 0.0073 0.0355 0.03
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0107 0.0683 0.063
Schistosoma mansoni cathepsin F (C01 family) 0.0234 0.1903 0.1903
Entamoeba histolytica cysteine protease, putative 0.0127 0.0867 0.0906
Loa Loa (eye worm) fibroinase 0.0234 0.1903 0.1857
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0657 0.2846
Entamoeba histolytica hypothetical protein 0.0105 0.0657 0.0636
Echinococcus multilocularis SH2 motif 0.0107 0.0683 0.063
Echinococcus multilocularis cathepsin b 0.0451 0.3991 0.3957
Trypanosoma cruzi cysteine peptidase, putative 0.0127 0.0867 0.1844
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0176 0.1346 0.5527
Brugia malayi cathepsin Z-like cysteine proteinase 0.0053 0.0161 0.0105
Schistosoma mansoni adapter molecule crk 0.0212 0.1691 0.1691
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0657 0.1294
Onchocerca volvulus 0.0234 0.1903 1
Brugia malayi Protein kinase domain containing protein 0.0139 0.0981 0.093
Schistosoma mansoni tyrosine kinase 0.1076 1 1
Entamoeba histolytica BAR/SH3 domain containing protein 0.0105 0.0657 0.0636
Echinococcus granulosus tyrosine kinase 0.0139 0.0981 0.093
Echinococcus multilocularis tyrosine protein kinase Srms 0.0971 0.8992 0.8986
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1076 1 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0234 0.1903 1
Plasmodium falciparum cysteine proteinase falcipain 1 0.0127 0.0867 0.4054
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0105 0.0657 0.0604
Onchocerca volvulus 0.0107 0.0683 0.2993
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0657 0.2846
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1076 1 1
Loa Loa (eye worm) hypothetical protein 0.0161 0.1197 0.1147
Leishmania major cathepsin L-like protease 0.0234 0.1903 1
Loa Loa (eye worm) hypothetical protein 0.0127 0.0871 0.0819
Brugia malayi cathepsin B-like cysteine proteinase 0.0451 0.3991 0.3957

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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