Detailed information for compound 1760292

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1461.53 | Formula: C65H92N18O21
  • H donors: 22 H acceptors: 21 LogP: -5.19 Rotable bonds: 52
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC[C@H]1O[C@@H](NC(=O)CCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)NCC(=O)N)CCCNC(=N)N)CC(C)C)Cc2ccc(cc2)O)CO)Cc2c[nH]c3c2cccc3)Cc2[nH]cnc2)CCC(=O)O)[C@@H]([C@H]([C@H]1O)O)O
  • InChi: 1S/C65H92N18O21/c1-32(2)21-41(58(98)77-40(9-5-19-70-65(67)68)64(103)83-20-6-10-46(83)62(102)72-27-48(66)87)76-51(90)28-73-56(96)42(22-33-11-13-36(86)14-12-33)78-61(101)45(29-84)81-59(99)43(23-34-25-71-38-8-4-3-7-37(34)38)79-60(100)44(24-35-26-69-31-74-35)80-57(97)39(15-18-52(91)92)75-49(88)16-17-50(89)82-63-55(95)54(94)53(93)47(30-85)104-63/h3-4,7-8,11-14,25-26,31-32,39-47,53-55,63,71,84-86,93-95H,5-6,9-10,15-24,27-30H2,1-2H3,(H2,66,87)(H,69,74)(H,72,102)(H,73,96)(H,75,88)(H,76,90)(H,77,98)(H,78,101)(H,79,100)(H,80,97)(H,81,99)(H,82,89)(H,91,92)(H4,67,68,70)/t39-,40-,41-,42-,43-,44-,45-,46-,47+,53-,54-,55+,63+/m0/s1
  • InChiKey: WVMXIWHRTFJIDR-PZMPRIPXSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Onchocerca volvulus Serine\/threonine kinase homolog 0.0131 0.0302 0.1737
Brugia malayi Guanylyl cyclase protein 23 0.0082 0.0051 0.0059
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0243 0.0882 0.0836
Entamoeba histolytica protein kinase domain containing protein 0.0122 0.0256 0.0352
Echinococcus granulosus protein kinase c epsilon type 0.0137 0.0333 0.0305
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Loa Loa (eye worm) TK/FER protein kinase 0.0082 0.0051 0.0059
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0105 0.0168 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0237 0.022
Brugia malayi Receptor family ligand binding region containing protein 0.0082 0.0051 0.0059
Echinococcus granulosus protein kinase shaggy 0.0122 0.0256 0.0227
Echinococcus multilocularis tyrosine kinase 0.0152 0.041 0.0361
Echinococcus multilocularis tyrosine protein kinase Blk 0.0186 0.0589 0.0541
Brugia malayi P38 map kinase family protein 2 0.0415 0.1767 0.2052
Echinococcus granulosus retinal guanylyl cyclase 2 0.0082 0.0051 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0145 0.0373 0.1523
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0123 0.026 0.0361
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0082 0.0051 0.0034
Entamoeba histolytica hypothetical protein 0.0981 0.4691 0.8
Loa Loa (eye worm) TK/FER protein kinase 0.0082 0.0051 0.0059
Schistosoma mansoni protein kinase 0.0101 0.0149 0.0132
Loa Loa (eye worm) TK/FER protein kinase 0.0152 0.041 0.0477
Schistosoma mansoni atypical protein kinase C 0.0134 0.0319 0.0302
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0585 0.2648 0.3075
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0461 0.2009 0.2333
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0145 0.0373 0.0555
Loa Loa (eye worm) AGC/PKA protein kinase 0.0145 0.0373 0.0434
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Schistosoma mansoni protein kinase 0.0101 0.0149 0.0132
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0051 0.0034
Echinococcus granulosus activated cdc42 kinase 1 0.0082 0.0051 0.0022
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0122 0.0256 0.1853
Onchocerca volvulus 0.0152 0.041 0.2488
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0082 0.0051 0.0022
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0125 0.0275 0.0225
Loa Loa (eye worm) TK protein kinase 0.0082 0.0051 0.0059
Plasmodium vivax protein kinase, putative 0.0095 0.0117 0.0685
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0123 0.026 0.2191
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0051 0.0071
Loa Loa (eye worm) SRC-1 0.0222 0.0775 0.09
Loa Loa (eye worm) TK/FAK protein kinase 0.0082 0.0051 0.0059
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0195 0.0636 0.0588
Giardia lamblia Phosphatidylinositol 4-kinase 0.0123 0.026 0.0619
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0243 0.0882 0.1025
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0666 0.3063 0.3027
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Loa Loa (eye worm) TK/INSR protein kinase 0.1741 0.861 1
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Onchocerca volvulus 0.0362 0.1495 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0082 0.0051 0.0034
Loa Loa (eye worm) hypothetical protein 0.0152 0.041 0.0477
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.0302 0.05
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0222 0.0775 0.0727
Loa Loa (eye worm) phosphatidylinositol 3 0.0422 0.1805 0.2096
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0415 0.1767 0.2958
Schistosoma mansoni tyrosine kinase 0.0188 0.0596 0.058
Brugia malayi Protein kinase domain containing protein 0.0911 0.4328 0.5027
Echinococcus granulosus TGF-beta receptor type-1 0.0104 0.0163 0.0133
Schistosoma mansoni tyrosine kinase 0.1073 0.5164 0.5156
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni tyrosine kinase 0.0943 0.4492 0.4482
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Giardia lamblia Kinase, CMGC MAPK 0.0178 0.0547 0.1468
Echinococcus multilocularis serine threonine protein kinase 0.0193 0.0621 0.0573
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.042 0.0702
Giardia lamblia Kinase, CMGC GSK 0.0122 0.0256 0.0605
Loa Loa (eye worm) hypothetical protein 0.0403 0.1705 0.198
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0267 0.1006 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0082 0.0051 0.0034
Plasmodium falciparum tyrosine kinase-like protein 0.0106 0.0176 0.1313
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Brugia malayi serine/threonine-protein kinase plk-2 0.0131 0.0302 0.0351
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0415 0.1767 0.2052
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Schistosoma mansoni ephrin receptor 0.0101 0.0151 0.0133
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Loa Loa (eye worm) TK/FER protein kinase 0.0082 0.0051 0.0059
Leishmania major protein kinase A catalytic subunit isoform 1 0.0145 0.0373 0.1878
Plasmodium falciparum serine/threonine protein kinase, putative 0.0195 0.0636 0.6125
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0105 0.0168 0.0139
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0082 0.0051 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Brugia malayi MAP kinase sur-1 0.0178 0.0547 0.0635
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0106 0.0172 0.02
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0492 0.2166 1
Schistosoma mansoni protein kinase 0.0167 0.0488 0.0471
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0082 0.0051 0.0059
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0085 0.0066 0.0015
Loa Loa (eye worm) hypothetical protein 0.0712 0.3303 0.3837
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0154 0.042 0.0488
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0328 0.0545
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0082 0.0051 0.0059
Echinococcus multilocularis epidermal growth factor receptor 0.1257 0.6113 0.6093
Trichomonas vaginalis CMGC family protein kinase 0.0178 0.0547 0.092
Loa Loa (eye worm) TK protein kinase 0.0082 0.0051 0.0059
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0089 0.0085 0.0058
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Giardia lamblia Kinase, CMGC GSK 0.0122 0.0256 0.0605
Loa Loa (eye worm) hypothetical protein 0.0145 0.0373 0.0434
Echinococcus multilocularis raf serine:threonine protein kinase 0.0111 0.0203 0.0152
Trichomonas vaginalis AGC family protein kinase 0.0195 0.0636 0.1072
Echinococcus granulosus RNA directed DNA polymerase 0.0085 0.0066 0.0037
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0468 0.2042 0.3433
Onchocerca volvulus 0.0152 0.041 0.2488
Entamoeba histolytica protein kinase, putative 0.0105 0.0168 0.0202
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0243 0.0882 0.0866
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0222 0.0775 0.0727
Loa Loa (eye worm) phosphatidylinositol 3 0.1443 0.7072 0.8214
Echinococcus granulosus tyrosine protein kinase Srms 0.0152 0.041 0.0382
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Entamoeba histolytica protein kinase, putative 0.0136 0.0328 0.0478
Echinococcus granulosus tyrosine protein kinase Src42A 0.0222 0.0775 0.0747
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0168 0.0151
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0122 0.0256 0.0297
Echinococcus multilocularis ephrin type A receptor 4 A 0.0482 0.2117 0.2077
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0145 0.0373 0.0555
Entamoeba histolytica protein kinase, putative 0.0122 0.0256 0.0352
Loa Loa (eye worm) hypothetical protein 0.0085 0.0068 0.0078
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Brugia malayi Furin-like cysteine rich region family protein 0.1257 0.6113 0.71
Echinococcus granulosus mitogen activated protein kinase 0.0178 0.0547 0.0519
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0137 0.0333 0.0387
Brugia malayi SH2 domain containing protein 0.0189 0.0604 0.0702
Toxoplasma gondii AGC kinase 0.0129 0.0294 0.2197
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0154 0.042 0.0488
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0267 0.1006 0.8651
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0145 0.0373 0.0555
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0222 0.0775 0.0727
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0267 0.1006 1
Trichomonas vaginalis protein kinase atn1, putative 0.0082 0.0051 0.0071
Trichomonas vaginalis AGC family protein kinase 0.0195 0.0636 0.1072
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Echinococcus granulosus NDR protein kinase 0.0105 0.0168 0.0139
Loa Loa (eye worm) hypothetical protein 0.0085 0.0068 0.0078
Onchocerca volvulus 0.0152 0.041 0.2488
Echinococcus multilocularis insulin receptor 0.1741 0.861 0.8603
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.042 0.0702
Echinococcus granulosus mitogen activated protein kinase 11 0.0415 0.1767 0.1742
Brugia malayi Fibronectin type III domain containing protein 0.0085 0.0068 0.0078
Loa Loa (eye worm) TK protein kinase 0.0082 0.0051 0.0059
Schistosoma mansoni protein kinase 0.0195 0.0636 0.0619
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0492 0.2166 0.3646
Trichomonas vaginalis STE family protein kinase 0.0082 0.0051 0.0071
Toxoplasma gondii aurora kinase 0.0195 0.0636 0.5299
Echinococcus multilocularis tyrosine protein kinase csk 0.012 0.0245 0.0195
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0585 0.2648 0.2626
Echinococcus granulosus aurora kinase A 0.0195 0.0636 0.0608
Schistosoma mansoni cell adhesion molecule 0.0097 0.0129 0.0112
Loa Loa (eye worm) RGC/RGC protein kinase 0.0082 0.0051 0.0059
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0145 0.0373 0.3375
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0112 0.0206 0.0177
Trypanosoma brucei cdc2-related kinase 3 0.0154 0.042 0.1744
Brugia malayi Tyrosine-protein kinase PR2 0.0082 0.0051 0.0059
Echinococcus granulosus tyrosine protein kinase Fyn 0.0222 0.0775 0.0747
Brugia malayi protein-tyrosine kinase 0.0186 0.0589 0.0684
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0203 0.033
Echinococcus multilocularis serine:threonine protein kinase N2 0.0404 0.171 0.1667
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0122 0.0256 0.0205
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0082 0.0051 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0131 0.0302 0.0351
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trypanosoma brucei protein kinase, putative 0.0122 0.0256 0.0967
Leishmania major protein kinase A catalytic subunit 0.0145 0.0373 0.1878
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0222 0.0775 0.0727
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0178 0.0547 0.289
Onchocerca volvulus Tyrosine kinase homolog 0.0112 0.0206 0.1075
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0152 0.041 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0051 0.0071
Brugia malayi Protein kinase domain containing protein 0.0152 0.041 0.0477
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0152 0.041 0.0361
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.051 0.0494
Schistosoma mansoni protein kinase 0.0082 0.0051 0.0034
Toxoplasma gondii AGC kinase 0.0145 0.0373 0.2919
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0123 0.026 0.0243
Echinococcus granulosus natriuretic peptide receptor 1 0.0082 0.0051 0.0022
Entamoeba histolytica cell division protein kinase 2, putative 0.0154 0.042 0.0636
Echinococcus granulosus tyrosine protein kinase Fyn 0.0222 0.0775 0.0747
Echinococcus multilocularis microtubule associated protein 2 0.201 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.042 0.0403
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.0302 0.05
Loa Loa (eye worm) hypothetical protein 0.0082 0.0051 0.0059
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0222 0.0775 0.0727
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0606 0.2754 0.2732
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0105 0.0168 0.0195
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0195 0.0636 0.1008
Echinococcus granulosus tyrosine kinase 0.0082 0.0051 0.0022
Loa Loa (eye worm) hypothetical protein 0.0076 0.0021 0.0025
Echinococcus granulosus protein kinase c iota type 0.0134 0.0319 0.0291
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0123 0.026 0.2191
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0051 0.0071
Loa Loa (eye worm) RGC/RGC protein kinase 0.0082 0.0051 0.0059
Loa Loa (eye worm) hypothetical protein 0.0082 0.0051 0.0059
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0145 0.0373 0.0345
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.176 0.8709 0.8703
Loa Loa (eye worm) protein kinase domain-containing protein 0.0082 0.0051 0.0059
Entamoeba histolytica cell division protein kinase 2, putative 0.0154 0.042 0.0636
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0171 0.051 0.0593
Echinococcus granulosus fibroblast growth factor receptor 4 0.0666 0.3063 0.3042
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Loa Loa (eye worm) SH2 domain-containing protein 0.0107 0.018 0.021
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trypanosoma cruzi cdc2-related kinase 1 0.0154 0.042 0.0636
Schistosoma mansoni serine/threonine kinase 0.0105 0.0168 0.0151
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0666 0.3063 0.3042
Echinococcus granulosus epidermal growth factor receptor 0.1025 0.4916 0.4901
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0222 0.0775 0.0727
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0105 0.0168 0.0117
Loa Loa (eye worm) hypothetical protein 0.0108 0.0185 0.0215
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni tyrosine kinase 0.0943 0.4492 0.4482
Loa Loa (eye worm) AUR protein kinase 0.0195 0.0636 0.0739
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0492 0.2166 0.2515
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Brugia malayi cell division control protein 2 homolog 0.0154 0.042 0.0488
Loa Loa (eye worm) thyroid receptor interactor 0.0259 0.0966 0.1122
Echinococcus granulosus tyrosine protein kinase Fyn 0.0222 0.0775 0.0747
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0243 0.0882 0.1433
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0373 0.0356
Brugia malayi Hr1 repeat family protein 0.0508 0.225 0.2614
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0222 0.0775 0.0727
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0091 0.0098 0.0114
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Brugia malayi phosphoinositide-dependent protein kinase I 0.0171 0.051 0.0593
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Loa Loa (eye worm) hypothetical protein 0.0825 0.3884 0.4512
Loa Loa (eye worm) hypothetical protein 0.0078 0.003 0.0034
Schistosoma mansoni tyrosine protein kinase 0.0082 0.0051 0.0034
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0122 0.0256 0.0297
Echinococcus multilocularis cyclin dependent kinase 5 0.0154 0.042 0.0371
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0104 0.0163 0.0112
Loa Loa (eye worm) TK/EGFR protein kinase 0.1257 0.6113 0.71
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0145 0.0373 0.0434
Echinococcus granulosus c src tyrosine kinase 0.0225 0.079 0.0763
Brugia malayi serine/threonine protein kinase 6 0.0195 0.0636 0.0739
Loa Loa (eye worm) hypothetical protein 0.0085 0.0066 0.0077
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.042 0.0702
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0178 0.0547 0.0855
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0243 0.0882 0.1433
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0082 0.0051 0.0059
Entamoeba histolytica tyrosin kinase, putative 0.0092 0.0103 0.0089
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0195 0.0636 0.6125
Giardia lamblia Kinase, CMGC CDK 0.0154 0.042 0.1092
Echinococcus granulosus ephrin type A receptor 4 A 0.0482 0.2117 0.2094
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0492 0.2166 0.3646
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0712 0.3303 0.3284
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0082 0.0051 0.0022
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0712 0.3303 0.3269
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0267 0.1006 0.0979
Echinococcus multilocularis c src tyrosine kinase 0.0225 0.079 0.0743
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0101 0.0149 0.0465
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0082 0.0051 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.1206 0.5851 1
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0105 0.0168 0.0139
Loa Loa (eye worm) TK/FER protein kinase 0.0082 0.0051 0.0059
Brugia malayi map kinase activated protein kinase protein 2 0.0585 0.2648 0.3075
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0105 0.0168 0.0117
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Brugia malayi ephrin receptor 1 precursor 0.0253 0.0931 0.1082
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0129 0.0294 0.0341
Echinococcus granulosus tyrosine protein kinase 0.0082 0.0051 0.0022
Loa Loa (eye worm) TK protein kinase 0.0117 0.023 0.0267
Brugia malayi Fes/CIP4 homology domain containing protein 0.0259 0.0966 0.1122
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0145 0.0373 0.0345
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0082 0.0051 0.0059
Loa Loa (eye worm) TK protein kinase 0.0696 0.3218 0.3738
Trypanosoma brucei protein kinase, putative 0.0101 0.0149 0.0465
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0186 0.0589 0.0561
Onchocerca volvulus 0.0122 0.0256 0.1416
Giardia lamblia Kinase, CMGC CDK 0.0154 0.042 0.1092
Schistosoma mansoni protein kinase 0.0082 0.0051 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0585 0.2648 0.2635
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0105 0.0168 0.0117
Loa Loa (eye worm) TK/RYK protein kinase 0.0082 0.0051 0.0059
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Trichomonas vaginalis CMGC family protein kinase 0.0178 0.0547 0.092
Echinococcus multilocularis roundabout 2 0.0127 0.0284 0.0234
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.0302 0.05
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni protein kinase 0.0082 0.0051 0.0034
Echinococcus multilocularis tyrosine protein kinase Abl 0.0188 0.0596 0.0548
Brugia malayi Immunoglobulin I-set domain containing protein 0.016 0.0453 0.0527
Brugia malayi Variant SH3 domain containing protein 0.0106 0.0172 0.02
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0154 0.042 0.0392
Trypanosoma brucei aurora B kinase 0.0195 0.0636 0.2765
Loa Loa (eye worm) TK/ABL protein kinase 0.0152 0.041 0.0477
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.1206 0.5851 1
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0222 0.0775 0.0747
Loa Loa (eye worm) TK/ROR protein kinase 0.0112 0.0206 0.024
Loa Loa (eye worm) TK protein kinase 0.0082 0.0051 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.0302 0.05
Loa Loa (eye worm) hypothetical protein 0.0106 0.0172 0.02
Echinococcus granulosus tyrosine protein kinase Lyn 0.0241 0.0873 0.0846
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0168 0.0271
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0773 0.0756
Echinococcus multilocularis N chimaerin 0.0099 0.0138 0.0087
Giardia lamblia Aurora kinase 0.0195 0.0636 0.1731
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0051 0.0071
Trypanosoma cruzi cdc2-related kinase 3 0.0154 0.042 0.0636
Echinococcus granulosus protein kinase C gamma type 0.0193 0.0621 0.0593
Schistosoma mansoni tyrosine kinase 0.1025 0.4916 0.4907
Loa Loa (eye worm) hypothetical protein 0.0082 0.0051 0.0059
Echinococcus granulosus tyrosine kinase 0.0186 0.0589 0.0561
Schistosoma mansoni tyrosine kinase 0.1025 0.4916 0.4907
Loa Loa (eye worm) hypothetical protein 0.019 0.0607 0.0705
Echinococcus multilocularis epidermal growth factor receptor 0.1025 0.4916 0.489
Echinococcus granulosus tyrosine protein kinase csk 0.012 0.0245 0.0216
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0082 0.0051 0.0071
Schistosoma mansoni tyrosine kinase 0.1741 0.861 0.8607
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Loa Loa (eye worm) TK/ACK protein kinase 0.0082 0.0051 0.0059
Loa Loa (eye worm) TK/CSK protein kinase 0.012 0.0245 0.0285
Schistosoma mansoni serine/threonine protein kinase 0.0508 0.225 0.2237
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.0636 0.0619
Loa Loa (eye worm) hypothetical protein 0.0362 0.1495 0.1737
Schistosoma mansoni protein kinase 0.0082 0.0051 0.0034
Brugia malayi Protein kinase domain containing protein 0.0105 0.0168 0.0195
Schistosoma mansoni ephrin receptor 0.0444 0.1919 0.1905
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0101 0.0149 0.017
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0099 0.0138 0.0109
Trypanosoma brucei cdc2-related kinase 1 0.0154 0.042 0.1744
Schistosoma mansoni tyrosine kinase 0.057 0.2568 0.2555
Brugia malayi Protein kinase domain containing protein 0.0152 0.041 0.0477
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.1206 0.5851 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0079 0.0035 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0195 0.0636 0.1072
Loa Loa (eye worm) hypothetical protein 0.0082 0.0051 0.0059
Schistosoma mansoni protein kinase 0.0082 0.0051 0.0034
Schistosoma mansoni vav2 0.0106 0.0173 0.0155
Loa Loa (eye worm) TK/FER protein kinase 0.0152 0.041 0.0477
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0195 0.0636 0.1008
Loa Loa (eye worm) hypothetical protein 0.0082 0.0051 0.0059
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0122 0.0256 0.0227
Onchocerca volvulus 0.0152 0.041 0.2488
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0082 0.0051 0.0059
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0243 0.0882 0.1025
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0145 0.0373 0.0345
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0373 0.0622
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0471 0.2056 0.2042
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0171 0.051 0.0462
Loa Loa (eye worm) TK/FER protein kinase 0.0082 0.0051 0.0059
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0267 0.1006 0.1705
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0178 0.0547 0.0855
Leishmania major phosphatidylinositol 3-kinase, putative 0.0267 0.1006 0.5564
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0492 0.2166 0.3691
Brugia malayi Variant SH3 domain containing protein 0.0106 0.0172 0.02
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0122 0.0256 0.0238
Brugia malayi RhoGAP domain containing protein 0.0099 0.0138 0.016
Entamoeba histolytica protein kinase, putative 0.0089 0.0085 0.0058
Schistosoma mansoni protein kinase 0.0082 0.0051 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Brugia malayi SRC-1 0.0222 0.0775 0.09
Schistosoma mansoni protein kinase 0.0101 0.0149 0.0132
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0082 0.0051 0.0059
Loa Loa (eye worm) TK/KIN16 protein kinase 0.016 0.0453 0.0527
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0099 0.0138 0.0121
Loa Loa (eye worm) TK/FER protein kinase 0.0152 0.041 0.0477
Echinococcus granulosus integrin linked protein kinase 0.0082 0.0051 0.0022
Loa Loa (eye worm) hypothetical protein 0.0082 0.0051 0.0059
Loa Loa (eye worm) TK/FER protein kinase 0.0082 0.0051 0.0059
Loa Loa (eye worm) TK/Met protein kinase 0.0082 0.0051 0.0059
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0145 0.0373 0.0324
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0328 0.0545
Echinococcus multilocularis mitogen activated protein kinase 11 0.0415 0.1767 0.1724
Brugia malayi p70 ribosomal S6 kinase beta 0.0129 0.0294 0.0341
Loa Loa (eye worm) hypothetical protein 0.0298 0.1164 0.1352
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0082 0.0051 0.0059
Echinococcus multilocularis tyrosine protein kinase csk 0.012 0.0245 0.0195
Trypanosoma cruzi polo-like protein kinase, putative 0.0131 0.0302 0.0432
Brugia malayi Protein kinase domain containing protein 0.0152 0.041 0.0477
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0328 0.0545
Loa Loa (eye worm) TK/FER protein kinase 0.0152 0.041 0.0477
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Echinococcus multilocularis serine:threonine protein kinase N2 0.0508 0.225 0.2211
Plasmodium vivax protein kinase Crk2 0.0154 0.042 0.3864
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.0302 0.0285
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0145 0.0373 0.0324
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0051 0.0034
Loa Loa (eye worm) hypothetical protein 0.0298 0.1164 0.1352
Loa Loa (eye worm) hypothetical protein 0.0082 0.0051 0.0059
Echinococcus multilocularis activin receptor type 0.0534 0.2381 0.2342
Echinococcus multilocularis mitogen activated protein kinase 14 0.0415 0.1767 0.1724
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0168 0.0151
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0167 0.0488 0.0567
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0154 0.042 0.215
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0178 0.0547 0.4494
Echinococcus granulosus raf serine:threonine protein kinase 0.0111 0.0203 0.0174
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Onchocerca volvulus 0.0189 0.0604 0.3831
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.1206 0.5851 1
Echinococcus multilocularis protein kinase c iota type 0.0134 0.0319 0.027
Schistosoma mansoni tyrosine kinase 0.0222 0.0775 0.0758
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0962 0.459 0.7841
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.1206 0.5851 1
Echinococcus multilocularis mitogen activated protein kinase 14 0.0415 0.1767 0.1724
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni protein tyrosine kinase 0.0082 0.0051 0.0034
Echinococcus granulosus serine:threonine protein kinase N2 0.0508 0.225 0.2227
Entamoeba histolytica PH domain containing protein kinase, putative 0.0151 0.0408 0.0615
Echinococcus granulosus Protein kinase C brain isozyme 0.0222 0.0773 0.0745
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Loa Loa (eye worm) hypothetical protein 0.0327 0.1316 0.1528
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni tyrosine kinase 0.0222 0.0775 0.0758
Loa Loa (eye worm) RGC/RGC protein kinase 0.0082 0.0051 0.0059
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0105 0.0168 0.0195
Echinococcus granulosus activated cdc42 kinase 1 0.0082 0.0051 0.0022
Schistosoma mansoni tyrosine kinase 0.0225 0.079 0.0774
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.0333 0.0316
Echinococcus multilocularis mitogen activated protein kinase 0.0178 0.0547 0.0498
Schistosoma mansoni tyrosine kinase 0.1257 0.6113 0.6106
Echinococcus multilocularis serine:threonine protein kinase N2 0.0105 0.0168 0.0117
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0101 0.0149 0.017
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0123 0.026 0.0302
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0243 0.0882 0.1433
Schistosoma mansoni nck2/grb4 0.0106 0.0172 0.0155
Loa Loa (eye worm) hypothetical protein 0.0135 0.0322 0.0374
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0145 0.0373 0.0555
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0415 0.1767 0.8113
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0981 0.4691 0.8
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0131 0.0302 0.0273
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.0178 0.0547 0.092
Loa Loa (eye worm) hypothetical protein 0.0298 0.1164 0.1352
Entamoeba histolytica protein kinase , putative 0.0195 0.0636 0.1008
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0178 0.0547 0.0855
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0962 0.459 0.7841
Entamoeba histolytica protein kinase domain containing protein 0.0092 0.0103 0.0089
Echinococcus granulosus N chimaerin 0.0099 0.0138 0.0109
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0104 0.0165 0.0114
Loa Loa (eye worm) TK/DDR protein kinase 0.0082 0.0051 0.0059
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0243 0.0882 0.3931
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1286 0.6264 0.6253
Loa Loa (eye worm) TK/FER protein kinase 0.0152 0.041 0.0477
Brugia malayi Protein kinase domain containing protein 0.0171 0.051 0.0593
Brugia malayi Tyrosine-protein kinase abl-1 0.0188 0.0596 0.0692
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0145 0.0373 0.3375
Echinococcus multilocularis mitogen activated protein kinase 11 0.0415 0.1767 0.1724
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0488 0.2143 0.3608
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Schistosoma mansoni hypothetical protein 0.0082 0.0051 0.0034
Brugia malayi bone morphogenetic protein type 1 receptor 0.0167 0.0488 0.0567
Trichomonas vaginalis CMGC family protein kinase 0.0122 0.0256 0.0421
Schistosoma mansoni nephrin 0.0115 0.0223 0.0206
Loa Loa (eye worm) AUR protein kinase 0.0195 0.0636 0.0739
Loa Loa (eye worm) TK/FER protein kinase 0.0152 0.041 0.0477
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0082 0.0051 0.0071
Giardia lamblia Kinase, PLK 0.0131 0.0302 0.0742
Loa Loa (eye worm) AUR protein kinase 0.0195 0.0636 0.0739
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.042 0.0403
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0492 0.2166 0.3691
Brugia malayi Immunoglobulin I-set domain containing protein 0.0696 0.3218 0.3738
Loa Loa (eye worm) hypothetical protein 0.0082 0.0051 0.0059
Loa Loa (eye worm) hypothetical protein 0.0494 0.2175 0.2526
Echinococcus granulosus insulin growth factor 1 receptor beta 0.176 0.8709 0.8706
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0082 0.0051 0.0059
Trypanosoma brucei rac serine-threonine kinase, putative 0.0136 0.0328 0.1311
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0099 0.0138 0.0087
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0606 0.2754 0.2717
Loa Loa (eye worm) phosphatidylinositol 3 0.0123 0.026 0.0302
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0547 0.053
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0168 0.0271
Loa Loa (eye worm) TK/EPH protein kinase 0.0543 0.2431 0.2824
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0082 0.0051 0.0059
Loa Loa (eye worm) TK/FER protein kinase 0.0152 0.041 0.0477
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.0302 0.05
Echinococcus granulosus tyrosine protein kinase Src42A 0.0104 0.0165 0.0136
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0222 0.0775 0.0747
Echinococcus granulosus protein kinase 0.0082 0.0051 0.0022
Echinococcus multilocularis Zinc finger, PHD finger 0.0267 0.1006 0.0959
Echinococcus multilocularis tyrosine protein kinase Srms 0.0186 0.0589 0.0541
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0154 0.042 0.215
Echinococcus granulosus protein tyrosine kinase 0.0082 0.0051 0.0022
Entamoeba histolytica protein kinase, putative 0.0171 0.051 0.0792
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0106 0.0172 0.02
Trichomonas vaginalis AGC family protein kinase 0.0171 0.051 0.0857
Echinococcus granulosus growth factor receptor bound protein 2 0.0106 0.0172 0.0143
Echinococcus granulosus roundabout 2 0.0127 0.0284 0.0256
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0171 0.051 0.0593
Echinococcus granulosus tyrosine protein kinase ABL1 0.0152 0.041 0.0382
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0107 0.0179 0.0208
Loa Loa (eye worm) AGC/PKN protein kinase 0.0508 0.225 0.2614
Echinococcus granulosus retinal guanylyl cyclase 2 0.0082 0.0051 0.0022
Echinococcus multilocularis TGF beta receptor type 1 0.0104 0.0163 0.0112
Echinococcus granulosus mitogen activated protein kinase 14 0.0415 0.1767 0.1742
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0145 0.0373 0.0324
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0243 0.0882 0.1494
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0715 0.3317 0.3853
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0203 0.0185
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Brugia malayi hypothetical protein 0.0085 0.0068 0.0078
Leishmania major protein kinase A catalytic subunit isoform 2 0.0145 0.0373 0.1878
Brugia malayi Protein kinase domain containing protein 0.0907 0.4308 0.5004
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0099 0.0138 0.016
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1025 0.4916 0.4901
Schistosoma mansoni serine/threonine RGC 0.0082 0.0051 0.0034
Echinococcus multilocularis cyclin dependent kinase 0.0154 0.042 0.0371
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0154 0.042 0.0488
Echinococcus multilocularis RNA directed DNA polymerase 0.0085 0.0066 0.0015
Echinococcus granulosus kinase suppressor of Ras 1 0.0082 0.0051 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0195 0.0636 0.1072
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0082 0.0051 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Brugia malayi intracellular kinase 0.0122 0.0256 0.0297
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.1136 0.549 0.9378
Trichomonas vaginalis AGC family protein kinase 0.0105 0.0168 0.0271
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1667 0.8232 0.8229
Echinococcus multilocularis serine:threonine protein kinase 38 0.0105 0.0168 0.0117
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0082 0.0051 0.0071
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0112 0.0206 0.0156
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0225 0.0262
Entamoeba histolytica protein kinase, putative 0.0117 0.023 0.0308
Echinococcus granulosus cyclin dependent kinase 1 0.0154 0.042 0.0392
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0131 0.0302 0.0252
Echinococcus granulosus tyrosine protein kinase HCK 0.0117 0.023 0.0201
Brugia malayi Protein kinase domain containing protein 0.0105 0.0168 0.0195
Loa Loa (eye worm) TK/FER protein kinase 0.0152 0.041 0.0477
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis protein tyrosine kinase, putative 0.0082 0.0051 0.0071
Brugia malayi Protein kinase domain containing protein 0.0136 0.0328 0.0381
Loa Loa (eye worm) AGC/PKA protein kinase 0.0145 0.0373 0.0434
Echinococcus multilocularis mitogen activated protein kinase 3 0.0178 0.0547 0.0498
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0328 0.0545
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0145 0.0373 0.2919
Brugia malayi Variant SH3 domain containing protein 0.0099 0.0138 0.016
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0125 0.0275 0.0246
Echinococcus granulosus tyrosine protein kinase Src64B 0.0222 0.0775 0.0747
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0154 0.042 0.3343
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Echinococcus granulosus twitchin 0.0115 0.0221 0.0192
Echinococcus granulosus insulin receptor 0.1741 0.861 0.8606
Loa Loa (eye worm) AGC/NDR protein kinase 0.0105 0.0168 0.0195
Entamoeba histolytica protein kinase, putative 0.0129 0.0294 0.0418
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Loa Loa (eye worm) hypothetical protein 0.0082 0.0051 0.0059
Brugia malayi Protein kinase domain containing protein 0.0152 0.041 0.0477
Brugia malayi Protein kinase domain containing protein 0.0091 0.0098 0.0114
Plasmodium vivax glycogen synthase kinase 3, putative 0.0122 0.0256 0.2141
Loa Loa (eye worm) TK protein kinase 0.0082 0.0051 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni growth factor receptor-bound protein 0.0106 0.0172 0.0155
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Entamoeba histolytica PH domain containing protein kinase, putative 0.0151 0.0408 0.0615
Echinococcus granulosus tyrosine protein kinase Blk 0.0186 0.0589 0.0561
Echinococcus granulosus receptor type guanylyl cyclase 0.0082 0.0051 0.0022
Giardia lamblia Kinase, AGC PKA 0.0145 0.0373 0.0953
Brugia malayi serine/threonine kinase 12 0.0195 0.0636 0.0739
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0178 0.0547 0.2345
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0082 0.0051 0.0022
Brugia malayi Raf kinase 0.0082 0.0051 0.0059
Trypanosoma cruzi polo-like protein kinase, putative 0.0131 0.0302 0.0432
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0152 0.041 0.0361
Echinococcus multilocularis 0.0123 0.026 0.021
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Schistosoma mansoni growth factor receptor-bound protein 0.0106 0.0172 0.0155
Loa Loa (eye worm) TK/ALK protein kinase 0.0082 0.0051 0.0059
Entamoeba histolytica serine/threonine protein kinase, putative 0.0131 0.0302 0.0432
Toxoplasma gondii AGC kinase 0.0145 0.0373 0.2919
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0243 0.0882 0.1494
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1667 0.8232 0.8223
Loa Loa (eye worm) hypothetical protein 0.0082 0.0051 0.0059
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0585 0.2648 0.261
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0415 0.1767 1
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Loa Loa (eye worm) hypothetical protein 0.0108 0.0185 0.0215
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Echinococcus multilocularis protein kinase shaggy 0.0122 0.0256 0.0205
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0243 0.0882 0.1433
Echinococcus granulosus cyclin dependent kinase 5 0.0154 0.042 0.0392
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0051 0.0071
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0737 0.343 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.0106 0.0176 0.1313
Trypanosoma cruzi cdc2-related kinase 1 0.0154 0.042 0.0636
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0123 0.026 0.0231
Schistosoma mansoni tyrosine kinase 0.0124 0.0268 0.0251
Echinococcus granulosus tyrosine protein kinase pr2 0.0082 0.0051 0.0022
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Brugia malayi Protein kinase domain containing protein 0.1741 0.861 1
Echinococcus granulosus tyrosine protein kinase csk 0.012 0.0245 0.0216
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0267 0.1006 0.099
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0145 0.0373 0.0324
Loa Loa (eye worm) hypothetical protein 0.0082 0.0051 0.0059
Echinococcus multilocularis growth factor receptor bound protein 2 0.0106 0.0172 0.0122
Echinococcus granulosus tyrosine protein kinase csk 0.012 0.0245 0.0216
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Loa Loa (eye worm) hypothetical protein 0.0082 0.0051 0.0059
Brugia malayi SH2 domain containing protein 0.0152 0.041 0.0477
Loa Loa (eye worm) TK protein kinase 0.0186 0.0589 0.0684
Echinococcus multilocularis neuroglian 0.0096 0.0123 0.0072
Trichomonas vaginalis AGC family protein kinase 0.0171 0.051 0.0857
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0222 0.0775 0.0727
Leishmania major protein kinase, putative 0.0195 0.0636 0.3408
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0051 0.0071
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0222 0.0775 0.0727
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.0302 0.05
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0243 0.0882 0.0855
Echinococcus multilocularis cyclin dependent kinase 1 0.0154 0.042 0.0371
Schistosoma mansoni tyrosine kinase 0.0666 0.3063 0.3051
Plasmodium falciparum protein kinase, putative 0.0101 0.0149 0.103
Schistosoma mansoni tyrosine kinase 0.1741 0.861 0.8607
Trichomonas vaginalis CMGC family protein kinase 0.0122 0.0256 0.0421
Entamoeba histolytica protein kinase domain containing protein 0.0195 0.0636 0.1008
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0099 0.0138 0.0121
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0295 0.1148 0.3247
Brugia malayi Variant SH3 domain containing protein 0.0079 0.0035 0.0041
Echinococcus granulosus cyclin dependent kinase 0.0154 0.042 0.0392
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0105 0.0168 0.0195
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0123 0.026 0.0989
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1206 0.5851 1
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0243 0.0882 0.4845
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0082 0.0051 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0328 0.0545
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Loa Loa (eye worm) hypothetical protein 0.0114 0.0218 0.0253
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0106 0.0172 0.0155
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0373 0.0356
Plasmodium falciparum protein kinase 5 0.0154 0.042 0.3864
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0152 0.041 0.0382
Schistosoma mansoni protein kinase 0.0104 0.0163 0.0145
Entamoeba histolytica protein kinase domain containing protein 0.0122 0.0256 0.0352
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0186 0.0589 0.0541
Loa Loa (eye worm) phosphatidylinositol 3 0.0094 0.0111 0.0129
Onchocerca volvulus 0.0298 0.1164 0.7708
Loa Loa (eye worm) serine/threonine protein kinase 0.0082 0.0051 0.0059
Loa Loa (eye worm) hypothetical protein 0.0085 0.0068 0.0078
Echinococcus multilocularis aurora kinase A 0.0195 0.0636 0.0588
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1206 0.5851 0.6796
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0195 0.0636 0.0608
Echinococcus multilocularis cyclin dependent kinase 1 0.0154 0.042 0.0371
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0101 0.0149 0.0099
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0123 0.026 0.0361
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0178 0.0547 0.289
Trypanosoma cruzi cdc2-related kinase 3 0.0154 0.042 0.0636
Loa Loa (eye worm) RGC/RGC protein kinase 0.0082 0.0051 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0082 0.0051 0.0071
Echinococcus granulosus retinal guanylyl cyclase 2 0.0082 0.0051 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0773 0.0756
Echinococcus granulosus epidermal growth factor receptor 0.1257 0.6113 0.6101
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0101 0.0149 0.0891
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0122 0.0256 0.1191
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0328 0.0545
Echinococcus granulosus NCK adaptor protein 0.0106 0.0172 0.0143
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0082 0.0051 0.0059
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0082 0.0051 0.0034
Schistosoma mansoni tyrosine kinase 0.1003 0.4805 0.4796
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0188 0.0596 0.058
Brugia malayi Protein kinase domain containing protein 0.0152 0.041 0.0477
Schistosoma mansoni microtubule-associated protein tau 0.201 1 1
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0082 0.0051 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0171 0.051 0.0857
Leishmania major protein kinase, putative 0.0101 0.0149 0.0573
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0122 0.0256 0.0352
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0082 0.0051 0.0034
Brugia malayi hypothetical protein 0.0152 0.041 0.0477
Entamoeba histolytica protein kinase, putative 0.0136 0.0328 0.0478
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0296 0.1154 1
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Brugia malayi Protein kinase c protein 2 0.0136 0.033 0.0383
Schistosoma mansoni protein kinase 0.0082 0.0051 0.0034
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1667 0.8232 0.8227
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0178 0.0547 0.0635
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.008 0.0042 0.0049
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Echinococcus multilocularis 0.0353 0.1448 0.1404
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Echinococcus multilocularis tyrosine protein kinase csk 0.012 0.0245 0.0195
Echinococcus granulosus serine:threonine protein kinase N2 0.0404 0.171 0.1685
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0091 0.0098 0.0114
Echinococcus multilocularis NCK adaptor protein 0.0106 0.0172 0.0122
Loa Loa (eye worm) TK/FER protein kinase 0.0152 0.041 0.0477
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0101 0.0149 0.012
Entamoeba histolytica protein kinase, putative 0.0195 0.0636 0.1008
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0145 0.0373 0.1523
Echinococcus multilocularis tyrosine protein kinase shark 0.1073 0.5164 0.514
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0051 0.0071
Echinococcus granulosus TGF beta receptor type 1 0.0104 0.0163 0.0133
Echinococcus multilocularis protein kinase c epsilon type 0.0137 0.0333 0.0284
Schistosoma mansoni tyrosine kinase 0.0082 0.0051 0.0034
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0131 0.0302 0.1462
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0422 0.1805 0.3024
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0082 0.0051 0.0022
Brugia malayi Sex muscle abnormal protein 5 0.0106 0.0172 0.02
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0168 0.0151
Echinococcus multilocularis tyrosine protein kinase HCK 0.0117 0.023 0.0179
Trypanosoma cruzi aurora B kinase, putative 0.0195 0.0636 0.1008
Echinococcus granulosus neuroglian 0.0096 0.0123 0.0094
Trypanosoma brucei polo-like protein kinase 0.0131 0.0302 0.1186
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0328 0.0545
Brugia malayi protein kinase C II. 0.0137 0.0333 0.0387
Brugia malayi hypothetical protein 0.0082 0.0051 0.0059
Trypanosoma brucei protein kinase, putative 0.0178 0.0547 0.2345
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0086 0.007 0.0102
Entamoeba histolytica protein kinase domain containing protein 0.0101 0.0149 0.017
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0145 0.0373 0.1523
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0195 0.0636 0.1008
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0082 0.0051 0.0071
Brugia malayi serine/threonine-protein kinase 6 0.0195 0.0636 0.0739
Brugia malayi MH2 domain containing protein 0.0116 0.0225 0.0262
Brugia malayi C-terminal src kinase protein 1 0.0082 0.0051 0.0059
Echinococcus granulosus tyrosine kinase 0.0152 0.041 0.0382
Entamoeba histolytica protein kinase, putative 0.0195 0.0636 0.1008
Schistosoma mansoni tyrosine kinase 0.0943 0.4492 0.4482
Echinococcus granulosus mitogen activated protein kinase 3 0.0178 0.0547 0.0519
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0051 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0911 0.4328 0.5027
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0666 0.3063 0.3027
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0492 0.2166 0.3691
Onchocerca volvulus 0.0152 0.041 0.2488
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0415 0.1767 0.2958
Loa Loa (eye worm) TK protein kinase 0.0082 0.0051 0.0059
Echinococcus granulosus tyrosine protein kinase shark 0.1073 0.5164 0.515
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.0302 0.05
Echinococcus multilocularis tyrosine protein kinase csk 0.012 0.0245 0.0195
Plasmodium falciparum glycogen synthase kinase 3 0.0122 0.0256 0.2141
Brugia malayi hypothetical protein 0.0082 0.0051 0.0059
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0225 0.0262
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0373 0.0356
Loa Loa (eye worm) TK protein kinase 0.0082 0.0051 0.0059
Loa Loa (eye worm) TK/FER protein kinase 0.0152 0.041 0.0477
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0178 0.0547 0.0855
Brugia malayi Protein kinase domain containing protein 0.0154 0.042 0.0488
Plasmodium falciparum protein kinase, putative 0.0106 0.0176 0.1313
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0171 0.051 0.0482
Loa Loa (eye worm) TK/FER protein kinase 0.0082 0.0051 0.0059
Brugia malayi Immunoglobulin I-set domain containing protein 0.0085 0.0068 0.0078
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Schistosoma mansoni adapter molecule crk 0.0106 0.0172 0.0155
Trichomonas vaginalis TK family protein kinase 0.0082 0.0051 0.0071
Brugia malayi integrin-linked kinase 0.0082 0.0051 0.0059
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0222 0.0773 0.0725
Brugia malayi Protein kinase domain containing protein 0.0082 0.0051 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Leishmania major phosphatidylinositol 4-kinase, putative 0.0123 0.026 0.1219
Trichomonas vaginalis TKL family protein kinase 0.0082 0.0051 0.0071
Echinococcus granulosus activin receptor type 0.0534 0.2381 0.2359
Trichomonas vaginalis CMGC family protein kinase 0.0178 0.0547 0.092
Loa Loa (eye worm) AGC/AKT protein kinase 0.0136 0.0328 0.0381

Activities

Activity type Activity value Assay description Source Reference
T1/2 (ADMET) = 51 min Half life in human Caco2 cell homogenates at 200 uM by LC-MS analysis ChEMBL. 23712085

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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