Detailed information for compound 176081

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 246.326 | Formula: C18H16N+
  • H donors: 0 H acceptors: 0 LogP: 4.59 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[n+]1ccc(c2c1cccc2)/C=C/c1ccccc1
  • InChi: 1S/C18H16N/c1-19-14-13-16(17-9-5-6-10-18(17)19)12-11-15-7-3-2-4-8-15/h2-14H,1H3/q+1/b12-11+
  • InChiKey: QDMHYLUMTJATFS-VAWYXSNFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens choline O-acetyltransferase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus choline O acetyltransferase Get druggable targets OG5_133080 All targets in OG5_133080
Schistosoma japonicum ko:K00623 choline O-acetyltransferase [EC2.3.1.6], putative Get druggable targets OG5_133080 All targets in OG5_133080
Echinococcus multilocularis choline O acetyltransferase Get druggable targets OG5_133080 All targets in OG5_133080
Loa Loa (eye worm) choline O-acetyltransferase Get druggable targets OG5_133080 All targets in OG5_133080
Schistosoma mansoni choline o-acyltransferase Get druggable targets OG5_133080 All targets in OG5_133080
Brugia malayi Choline O-acetyltransferase Get druggable targets OG5_133080 All targets in OG5_133080
Brugia malayi Choline O-acetyltransferase Get druggable targets OG5_133080 All targets in OG5_133080
Schistosoma japonicum Choline O-acetyltransferase, putative Get druggable targets OG5_133080 All targets in OG5_133080
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133080 All targets in OG5_133080
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei carnitine O-acetyltransferase, putative choline O-acetyltransferase 630 aa 632 aa 31.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cysteine proteinase 2 0.0379 0.2397 0.2397
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0031 0.0043 0.0062
Entamoeba histolytica cysteine proteinase, putative 0.0379 0.2397 0.2397
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0049 0.0162 0.0285
Giardia lamblia Encystation-specific protease 0.0154 0.0871 0.0831
Entamoeba histolytica cysteine protease, putative 0.0154 0.0871 0.0871
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Plasmodium vivax SET domain protein, putative 0.0091 0.0448 0.0889
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0154 0.0871 0.1233
Schistosoma mansoni flap endonuclease-1 0.0028 0.0023 0.0015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Onchocerca volvulus Cathepsin F homolog 0.0709 0.4635 0.9788
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Schistosoma mansoni choline o-acyltransferase 0.0198 0.1171 0.1664
Loa Loa (eye worm) hypothetical protein 0.003 0.003 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0154 0.0871 0.0871
Loa Loa (eye worm) hypothetical protein 0.0484 0.3109 0.445
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0157 0.0208
Brugia malayi cathepsin L precursor 0.0154 0.0871 0.1235
Trypanosoma cruzi carnitine/choline acetyltransferase, putative 0.003 0.003 0.0043
Loa Loa (eye worm) hypothetical protein 0.0106 0.0551 0.0774
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Trypanosoma brucei cysteine peptidase C (CPC) 0.0432 0.2757 0.5922
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0154 0.0871 0.1808
Giardia lamblia Cathepsin L precursor 0.0154 0.0871 0.0831
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.003 0.003 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0407 0.0407
Brugia malayi fibroinase precursor 0.0154 0.0871 0.1235
Loa Loa (eye worm) hypothetical protein 0.0051 0.0175 0.0234
Echinococcus granulosus cathepsin l1 0.0484 0.3109 0.445
Giardia lamblia Cathepsin B precursor 0.0432 0.2757 0.2726
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.005 0.0171 0.0228
Schistosoma mansoni cathepsin F (C01 family) 0.0484 0.3109 0.445
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.004 0.0021
Trypanosoma cruzi carnitine O-palmitoyltransferase II, putative 0.003 0.003 0.0043
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1054 0.6971 1
Loa Loa (eye worm) hypothetical protein 0.0365 0.2302 0.3291
Giardia lamblia Cathepsin B precursor 0.0432 0.2757 0.2726
Loa Loa (eye worm) cathepsin B 0.0432 0.2757 0.3945
Echinococcus granulosus lysine specific demethylase 5A 0.0183 0.1072 0.1522
Trichomonas vaginalis chromobox protein, putative 0.0092 0.0451 0.0451
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0048 0.0157 0.0276
Entamoeba histolytica cysteine proteinase, putative 0.0709 0.4635 0.4635
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0154 0.0871 0.1235
Leishmania major carnitine/choline acetyltransferase, putative 0.003 0.003 0.0065
Trypanosoma cruzi cruzipain precursor, putative 0.0225 0.1356 0.1945
Brugia malayi Cathepsin L-like precursor 0.0709 0.4635 0.6644
Loa Loa (eye worm) hypothetical protein 0.0154 0.0871 0.1233
Plasmodium vivax unspecified product 0.0154 0.0871 0.1808
Trypanosoma cruzi choline/carnitine O-acetyltransferase, putative 0.003 0.003 0.0043
Brugia malayi Cathepsin L-like precursor 0.0709 0.4635 0.6644
Brugia malayi cathepsin F-like cysteine proteinase 0.0154 0.0871 0.1235
Trichomonas vaginalis chromobox protein, putative 0.0152 0.086 0.086
Trypanosoma cruzi cysteine peptidase, putative 0.0379 0.2397 0.3438
Brugia malayi Cathepsin L-like precursor 0.0709 0.4635 0.6644
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0154 0.0871 0.1233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0871 0.0871
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0091 0.0112
Echinococcus granulosus peregrin 0.0152 0.0862 0.122
Echinococcus granulosus choline O acetyltransferase 0.0198 0.1171 0.1664
Onchocerca volvulus 0.0154 0.0871 0.1786
Plasmodium falciparum phd finger protein, putative 0.015 0.0844 0.1751
Brugia malayi Choline O-acetyltransferase 0.0198 0.1171 0.1667
Plasmodium vivax hypothetical protein, conserved 0.0049 0.0162 0.0265
Trypanosoma cruzi major cysteine proteinase, putative 0.0154 0.0871 0.1249
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.049 0.3153 0.4513
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0088 0.0425 0.0593
Brugia malayi Importin beta-1 subunit 0.0031 0.004 0.0042
Giardia lamblia Cathepsin B precursor 0.0154 0.0871 0.0831
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Plasmodium falciparum serine repeat antigen 6 0.0154 0.0871 0.1808
Echinococcus multilocularis peregrin 0.0152 0.0862 0.122
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Echinococcus multilocularis cysteine protease 0.0709 0.4635 0.6643
Echinococcus multilocularis cathepsin L cysteine protease 0.0709 0.4635 0.6643
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Loa Loa (eye worm) hypothetical protein 0.0225 0.1356 0.1931
Brugia malayi Cathepsin L-like precursor 0.0709 0.4635 0.6644
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0154 0.0871 0.0871
Loa Loa (eye worm) hypothetical protein 0.0257 0.1569 0.2237
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Plasmodium falciparum cysteine proteinase falcipain 1 0.0379 0.2397 0.5129
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0154 0.0871 0.0871
Schistosoma mansoni cathepsin F (C01 family) 0.0709 0.4635 0.6643
Trypanosoma cruzi cruzipain precursor, putative 0.0709 0.4635 0.6649
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0871 0.0871
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0091 0.0112
Brugia malayi jmjC domain containing protein 0.0183 0.1072 0.1525
Loa Loa (eye worm) jmjC domain-containing protein 0.0183 0.1072 0.1522
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Entamoeba histolytica cysteine proteinase, putative 0.0379 0.2397 0.2397
Entamoeba histolytica cysteine protease, putative 0.0154 0.0871 0.0871
Leishmania major carnitine palmitoyltransferase-like protein 0.003 0.003 0.0065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Loa Loa (eye worm) heterochromatin protein 1 0.0152 0.086 0.1218
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0048 0.0157 0.0226
Leishmania major cysteine peptidase A (CPA) 0.0709 0.4635 1
Brugia malayi CHD4 protein 0.0027 0.0012 0.0003
Loa Loa (eye worm) fibroinase 0.0709 0.4635 0.6643
Loa Loa (eye worm) flap endonuclease-1 0.0031 0.0043 0.0044
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1054 0.6971 1
Brugia malayi Cathepsin L-like precursor 0.0709 0.4635 0.6644
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.003 0.0043
Plasmodium falciparum flap endonuclease 1 0.0031 0.0043 0.0007
Schistosoma mansoni cathepsin F (C01 family) 0.0709 0.4635 0.6643
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.049 0.3153 0.4513
Brugia malayi cathepsin L-like precursor 0.0484 0.3109 0.4451
Plasmodium falciparum serine repeat antigen 3 0.0154 0.0871 0.1808
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.005 0.0171 0.0228
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.003 0.003 0.0043
Brugia malayi Papain family cysteine protease containing protein 0.0379 0.2397 0.3428
Brugia malayi Choline O-acetyltransferase 0.0198 0.1171 0.1667
Giardia lamblia PHD finger protein 15 0.015 0.0844 0.0805
Onchocerca volvulus 0.0709 0.4635 0.9788
Trypanosoma cruzi cysteine peptidase, putative 0.0709 0.4635 0.6649
Loa Loa (eye worm) jmjC domain-containing protein 0.0309 0.1925 0.2748
Schistosoma mansoni cathepsin C 0.0154 0.0871 0.1233
Brugia malayi RNA, U transporter 1 0.0088 0.0426 0.0597
Echinococcus granulosus cathepsin b 0.1054 0.6971 1
Toxoplasma gondii cathepsin B 0.0432 0.2757 0.5914
Onchocerca volvulus Cathepsin L homolog 0.0154 0.0871 0.1786
Entamoeba histolytica cysteine proteinase, putative 0.0709 0.4635 0.4635
Loa Loa (eye worm) hypothetical protein 0.0109 0.0572 0.0804
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0154 0.0871 0.1233
Entamoeba histolytica cysteine protease, putative 0.0154 0.0871 0.0871
Entamoeba histolytica cysteine protease, putative 0.0154 0.0871 0.0871
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0154 0.0871 0.0831
Treponema pallidum fructose-bisphosphate aldolase 0.1501 1 0.5
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0432 0.2757 0.5949
Loa Loa (eye worm) hypothetical protein 0.0709 0.4635 0.6643
Loa Loa (eye worm) hypothetical protein 0.0484 0.3109 0.445
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0154 0.0871 0.1233
Entamoeba histolytica hypothetical protein 0.0154 0.0871 0.0871
Plasmodium falciparum serine repeat antigen 8 0.0154 0.0871 0.1808
Echinococcus granulosus cathepsin L cysteine protease 0.0379 0.2397 0.3426
Brugia malayi Cathepsin L-like cysteine proteinase 0.0484 0.3109 0.4451
Giardia lamblia Fructose-bisphosphate aldolase 0.1501 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0283 0.0388
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0154 0.0871 0.1808
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0807 0.1141
Trypanosoma cruzi cysteine protease, putative 0.0379 0.2397 0.3438
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0154 0.0871 0.0831
Entamoeba histolytica cysteine protease, putative 0.0154 0.0871 0.0871
Echinococcus granulosus cathepsin L 0.0379 0.2397 0.3426
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0183 0.1072 0.1522
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.003 0.003 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0154 0.0871 0.0871
Brugia malayi Papain family cysteine protease containing protein 0.0709 0.4635 0.6644
Toxoplasma gondii cathepsin CPC2 0.0154 0.0871 0.1808
Giardia lamblia Cathepsin L precursor 0.0154 0.0871 0.0831
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0049 0.0162 0.0265
Brugia malayi Papain family cysteine protease containing protein 0.0379 0.2397 0.3428
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1054 0.6971 1
Plasmodium vivax unspecified product 0.0225 0.1356 0.2865
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0709 0.4635 0.6643
Loa Loa (eye worm) hypothetical protein 0.0154 0.0871 0.1233
Toxoplasma gondii PHD-finger domain-containing protein 0.015 0.0844 0.1751
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0432 0.2757 0.3945
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0154 0.0871 0.0831
Giardia lamblia Cathepsin B precursor 0.0154 0.0871 0.0831
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.003 0.003 0.0028
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0048 0.0157 0.0256
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0116 0.0617 0.0868
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Echinococcus granulosus cathepsin l1 0.0709 0.4635 0.6643
Giardia lamblia Cathepsin B precursor 0.0154 0.0871 0.0831
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0407 0.0407
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Toxoplasma gondii cathepsin CPC1 0.0154 0.0871 0.1808
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Echinococcus multilocularis phd:f box containing protein 0.0048 0.0157 0.0208
Brugia malayi Papain family cysteine protease containing protein 0.0154 0.0871 0.1235
Echinococcus granulosus jumonji domain containing protein 0.0208 0.1242 0.1767
Brugia malayi F/Y-rich N-terminus family protein 0.0054 0.0198 0.0269
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0432 0.2757 0.2757
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Trichomonas vaginalis chromobox protein, putative 0.0092 0.0451 0.0451
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Schistosoma mansoni phosphatidylserine receptor 0.0048 0.0157 0.0208
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0157 0.0208
Schistosoma mansoni cathepsin S (C01 family) 0.0154 0.0871 0.1233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0871 0.0871
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Brugia malayi Heterochromatin protein 1 0.0152 0.086 0.122
Brugia malayi Flap endonuclease-1 0.0031 0.0043 0.0047
Echinococcus granulosus cathepsin L 0.0154 0.0871 0.1233
Plasmodium vivax vivapain-2 0.0709 0.4635 1
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0154 0.0871 0.0871
Toxoplasma gondii cathepsin CPL 0.0709 0.4635 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0379 0.2397 0.2397
Brugia malayi Bromodomain containing protein 0.0041 0.0108 0.0139
Plasmodium falciparum serine repeat antigen 4 0.0154 0.0871 0.1808
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1054 0.6971 1
Onchocerca volvulus 0.0709 0.4635 0.9788
Echinococcus multilocularis jumonji domain containing protein 0.0208 0.1242 0.1767
Brugia malayi cathepsin B-like cysteine proteinase 0.1054 0.6971 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0154 0.0871 0.0831
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0154 0.0871 0.1808
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0379 0.2397 0.3426
Brugia malayi MH2 domain containing protein 0.0144 0.0807 0.1144
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0154 0.0871 0.1808
Onchocerca volvulus 0.0709 0.4635 0.9788
Giardia lamblia Cysteine protease 0.0154 0.0871 0.0831
Loa Loa (eye worm) cysteine protease 0.0709 0.4635 0.6643
Schistosoma mansoni jumonji/arid domain-containing protein 0.0183 0.1072 0.1522
Trypanosoma cruzi cysteine peptidase, putative 0.0225 0.1356 0.1945
Onchocerca volvulus 0.0709 0.4635 0.9788
Echinococcus granulosus jumonji domain containing 1A 0.0048 0.0157 0.0208
Plasmodium vivax serine-repeat antigen (SERA) 0.0154 0.0871 0.1808
Loa Loa (eye worm) hypothetical protein 0.015 0.0844 0.1196
Giardia lamblia Cathepsin L-like protease 0.0154 0.0871 0.0831
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0484 0.3109 0.446
Trypanosoma cruzi carnitine O-acetyltransferase, putative 0.003 0.003 0.0043
Echinococcus granulosus JmjC domain containing protein 4 0.0048 0.0157 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0448 0.0626
Giardia lamblia Cathepsin L precursor 0.0154 0.0871 0.0831
Entamoeba histolytica cysteine proteinase, putative 0.0379 0.2397 0.2397
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0154 0.0871 0.0871
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Loa Loa (eye worm) choline/Carnitine O-acyltransferase 0.003 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0225 0.1356 0.1931
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.003 0.0043
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0109 0.0572 0.0804
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0484 0.3109 0.3109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Brugia malayi SET domain containing protein 0.0028 0.0021 0.0015
Echinococcus granulosus cathepsin b 0.1054 0.6971 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0379 0.2397 0.2397
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0263 0.036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0871 0.0871
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Leishmania major hypothetical protein, conserved 0.0048 0.0157 0.034
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0154 0.0871 0.0871
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Onchocerca volvulus 0.0709 0.4635 0.9788
Plasmodium vivax flap endonuclease 1, putative 0.0031 0.0043 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.003 0.0043
Brugia malayi Cathepsin L-like precursor 0.0225 0.1356 0.1933
Echinococcus granulosus cysteine protease 0.0379 0.2397 0.3426
Giardia lamblia Cathepsin L precursor 0.0154 0.0871 0.0831
Echinococcus multilocularis cathepsin L cysteine protease 0.0709 0.4635 0.6643
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0154 0.0871 0.1233
Plasmodium falciparum serine repeat antigen 1 0.0154 0.0871 0.1808
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0709 0.4635 0.4635
Echinococcus granulosus cathepsin l cysteine peptidase 0.0709 0.4635 0.6643
Brugia malayi jmjC domain containing protein 0.0048 0.0157 0.0211
Onchocerca volvulus Cathepsin L homolog 0.0709 0.4635 0.9788
Schistosoma mansoni chromobox protein 0.0152 0.086 0.1218
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0048 0.0157 0.0256
Brugia malayi Pre-SET motif family protein 0.0636 0.4139 0.5932
Loa Loa (eye worm) hypothetical protein 0.0198 0.1171 0.1664
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1054 0.6971 1
Loa Loa (eye worm) hypothetical protein 0.0225 0.1356 0.1931
Loa Loa (eye worm) hypothetical protein 0.0048 0.0157 0.0208
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0733 0.4798 0.5
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0154 0.0871 0.1808
Giardia lamblia Cathepsin B precursor 0.0432 0.2757 0.2726
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0379 0.2397 0.3438
Giardia lamblia Cysteine protease 0.0154 0.0871 0.0831
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1501 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0154 0.0871 0.1233
Schistosoma mansoni hypothetical protein 0.0049 0.0162 0.0214
Toxoplasma gondii PHD-finger domain-containing protein 0.0049 0.0162 0.0265
Plasmodium falciparum serine repeat antigen 7 0.0154 0.0871 0.1808
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Loa Loa (eye worm) hypothetical protein 0.0484 0.3109 0.445
Echinococcus multilocularis jumonji domain containing 1A 0.0048 0.0157 0.0208
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0048 0.0157 0.0208
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0154 0.0871 0.1233
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0448 0.0889
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Echinococcus multilocularis cathepsin b 0.1054 0.6971 1
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0154 0.0871 0.1808
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Plasmodium vivax vivapain-3 0.0379 0.2397 0.5129
Trypanosoma cruzi cysteine peptidase, putative 0.0709 0.4635 0.6649
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0709 0.4635 0.6643
Trichomonas vaginalis set domain proteins, putative 0.0724 0.4735 0.4735
Onchocerca volvulus 0.0709 0.4635 0.9788
Trypanosoma cruzi major cysteine proteinase, putative 0.0154 0.0871 0.1249
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0031 0.0043 0.0028
Plasmodium vivax vivapain-1 0.0379 0.2397 0.5129
Loa Loa (eye worm) hypothetical protein 0.0046 0.0139 0.0182
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Echinococcus multilocularis cathepsin L 0.0379 0.2397 0.3426
Echinococcus granulosus carnitine O palmitoyltransferase 2 0.003 0.003 0.0026
Schistosoma mansoni choline o-acyltransferase 0.003 0.003 0.0026
Brugia malayi Cathepsin L-like precursor 0.0709 0.4635 0.6644
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0871 0.0871
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Brugia malayi cathepsin L-like cysteine proteinase 0.0154 0.0871 0.1235
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0154 0.0871 0.1808
Echinococcus multilocularis carnitine O palmitoyltransferase 2 0.003 0.003 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0871 0.0871
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0636 0.4139 0.593
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0709 0.4635 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Schistosoma mansoni protein phosphatase 2C 0.0048 0.0157 0.0208
Echinococcus granulosus carnitine O palmitoyltransferase 1 liver 0.003 0.003 0.0026
Giardia lamblia Hypothetical protein 0.0154 0.0871 0.0831
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0154 0.0871 0.1808
Brugia malayi jmjC domain containing protein 0.0048 0.0157 0.0211
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Trypanosoma cruzi carnitine/choline acetyltransferase, putative 0.003 0.003 0.0043
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0154 0.0871 0.1233
Entamoeba histolytica cysteine proteinase, putative 0.0379 0.2397 0.2397
Trichomonas vaginalis flap endonuclease-1, putative 0.0031 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0871 0.0871
Trypanosoma cruzi cysteine peptidase, putative 0.0709 0.4635 0.6649
Echinococcus granulosus chromobox protein 1 0.0152 0.086 0.1218
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Plasmodium falciparum JmjC domain-containing protein, putative 0.0048 0.0157 0.0256
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Onchocerca volvulus 0.0724 0.4735 1
Brugia malayi jmjC domain containing protein 0.049 0.3153 0.4514
Echinococcus multilocularis carnitine O palmitoyltransferase 1, liver 0.003 0.003 0.0026
Echinococcus granulosus flap endonuclease 1 0.0031 0.0043 0.0044
Loa Loa (eye worm) PHD-finger family protein 0.015 0.0844 0.1196
Entamoeba histolytica Flap nuclease, putative 0.0031 0.0043 0.0043
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0154 0.0871 0.1233
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0225 0.1356 0.1933
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0085 0.0407 0.0802
Giardia lamblia Cysteine protease 0.0154 0.0871 0.0831
Brugia malayi Bromodomain containing protein 0.0152 0.0862 0.1223
Onchocerca volvulus 0.0067 0.0283 0.0536
Plasmodium falciparum serine repeat antigen 5 0.0154 0.0871 0.1808
Giardia lamblia Cathepsin B precursor 0.0154 0.0871 0.0831
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0092 0.0451 0.0895
Brugia malayi Papain family cysteine protease containing protein 0.0154 0.0871 0.1235
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0709 0.4635 0.6643
Echinococcus granulosus PHD finger protein rhinoceros 0.015 0.0844 0.1196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Entamoeba histolytica cysteine proteinase 1, putative 0.0379 0.2397 0.2397
Schistosoma mansoni jumonji domain containing protein 0.0048 0.0157 0.0208
Brugia malayi Cathepsin L-like precursor 0.0484 0.3109 0.4451
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0225 0.1356 0.1931
Brugia malayi Pre-SET motif family protein 0.0091 0.0448 0.0628
Brugia malayi cathepsin Z-like cysteine proteinase 0.0154 0.0871 0.1235
Echinococcus multilocularis JmjC domain containing protein 4 0.0048 0.0157 0.0208
Loa Loa (eye worm) hypothetical protein 0.0154 0.0871 0.1233
Loa Loa (eye worm) carnitine O-palmitoyltransferase I isoform 0.003 0.003 0.0026
Echinococcus multilocularis lysine specific demethylase 6a 0.0048 0.0157 0.0208
Echinococcus granulosus importin subunit beta 1 0.0031 0.004 0.0039
Onchocerca volvulus 0.0365 0.2302 0.483
Loa Loa (eye worm) hypothetical protein 0.1054 0.6971 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0709 0.4635 0.6643
Echinococcus multilocularis choline O acetyltransferase 0.0198 0.1171 0.1664
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0709 0.4635 0.4635
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0154 0.0871 0.1233
Trypanosoma cruzi cysteine proteinase, putative 0.0379 0.2397 0.3438
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0031 0.0043 0.0093
Brugia malayi hypothetical protein 0.0365 0.2302 0.3293
Echinococcus multilocularis flap endonuclease 1 0.0031 0.0043 0.0044
Echinococcus multilocularis PHD finger protein rhinoceros 0.015 0.0844 0.1196
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.003 0.0043
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Giardia lamblia Cathepsin L precursor 0.0154 0.0871 0.0831
Onchocerca volvulus 0.0116 0.0617 0.1247
Schistosoma mansoni chromobox protein 0.0152 0.086 0.1218
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.004 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0157 0.0208
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0709 0.4635 1
Plasmodium falciparum serine repeat antigen 2 0.0154 0.0871 0.1808
Loa Loa (eye worm) hypothetical protein 0.0154 0.0871 0.1233
Echinococcus multilocularis chromobox protein 1 0.0152 0.086 0.1218
Schistosoma mansoni phd/f-box containing protein 0.0048 0.0157 0.0208
Schistosoma mansoni bromodomain containing protein 0.0068 0.0289 0.0397
Entamoeba histolytica cysteine protease, putative 0.0709 0.4635 0.4635
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0154 0.0871 0.1233
Plasmodium vivax unspecified product 0.0379 0.2397 0.5129
Echinococcus multilocularis cathepsin L 0.0154 0.0871 0.1233
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0048 0.0157 0.0226
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0154 0.0871 0.0871
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0154 0.0871 0.1233
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.003 0.0043
Loa Loa (eye worm) hypothetical protein 0.0106 0.0551 0.0774
Entamoeba histolytica cysteine protease, putative 0.0154 0.0871 0.0871
Brugia malayi AF-10 protein 0.0049 0.0162 0.0217
Echinococcus multilocularis chromobox protein 1 0.0152 0.086 0.1218
Schistosoma mansoni hypothetical protein 0.015 0.0844 0.1196
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0154 0.0871 0.0871
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0154 0.0871 0.0871
Brugia malayi chromobox protein homolog 3 0.0085 0.0407 0.057
Loa Loa (eye worm) hypothetical protein 0.0048 0.0157 0.0208
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Onchocerca volvulus 0.0484 0.3109 0.6544
Echinococcus multilocularis cysteine protease 0.0709 0.4635 0.6643
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0154 0.0871 0.1808
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0109 0.0572 0.0804
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0154 0.0871 0.1808
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0049 0.0162 0.0265
Onchocerca volvulus 0.0709 0.4635 0.9788
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Brugia malayi PHD-finger family protein 0.0051 0.0175 0.0237
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.033 0.2068 0.2955
Schistosoma mansoni hypothetical protein 0.033 0.2068 0.2955
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0871 0.0871
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0031 0.0043 0.0007
Schistosoma mansoni importin beta-1 0.0031 0.004 0.0039
Echinococcus granulosus cathepsin L cysteine proteinase 0.0709 0.4635 0.6643
Plasmodium vivax serine-repeat antigen (SERA) 0.0154 0.0871 0.1808
Giardia lamblia Cathepsin L-like protease 0.0154 0.0871 0.0831
Brugia malayi Bromodomain containing protein 0.008 0.0374 0.0522
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0154 0.0871 0.1808
Giardia lamblia Cathepsin B precursor 0.0154 0.0871 0.0831
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0154 0.0871 0.1808
Plasmodium falciparum serine repeat antigen 9 0.0154 0.0871 0.1808
Echinococcus granulosus snurportin 1 0.033 0.2068 0.2955
Giardia lamblia Cysteine protease 0.0154 0.0871 0.0831
Giardia lamblia Cathepsin L precursor 0.0154 0.0871 0.0831
Brugia malayi PHD-finger family protein 0.015 0.0844 0.1198
Plasmodium vivax JmjC domain containing protein 0.0048 0.0157 0.0256
Brugia malayi cathepsin F-like cysteine proteinase 0.0225 0.1356 0.1933
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.003 0.003 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0239 0.0239
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Loa Loa (eye worm) hypothetical protein 0.0154 0.0871 0.1233
Brugia malayi Papain family cysteine protease containing protein 0.0154 0.0871 0.1235
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0379 0.2397 0.3426
Trypanosoma cruzi cysteine proteinase, putative 0.0379 0.2397 0.3438
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.0039
Echinococcus multilocularis snurportin 1 0.033 0.2068 0.2955
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0154 0.0871 0.0871
Brugia malayi jmjC domain containing protein 0.0048 0.0157 0.0211
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0379 0.2397 0.3426
Leishmania major choline/Carnitine o-acyltransferase-like protein 0.003 0.003 0.0065
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0263 0.036
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0807 0.1141
Loa Loa (eye worm) hypothetical protein 0.0154 0.0871 0.1233
Echinococcus multilocularis importin subunit beta 1 0.0031 0.004 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0379 0.2397 0.5139
Brugia malayi hypothetical protein 0.0106 0.0551 0.0776
Loa Loa (eye worm) hypothetical protein 0.0044 0.0125 0.0162
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0049 0.0162 0.0285
Echinococcus granulosus lysine specific demethylase 6a 0.0048 0.0157 0.0208
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.003 0.003 0.0043
Brugia malayi Cathepsin L-like precursor 0.0484 0.3109 0.4451
Echinococcus multilocularis lysine specific demethylase 5A 0.0181 0.1058 0.1502
Loa Loa (eye worm) hypothetical protein 0.0041 0.0108 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Onchocerca volvulus Cathepsin L homolog 0.0709 0.4635 0.9788
Echinococcus multilocularis cathepsin b 0.1054 0.6971 1
Trichomonas vaginalis chromobox protein, putative 0.0152 0.086 0.086
Entamoeba histolytica cysteine proteinase, putative 0.0484 0.3109 0.3109
Plasmodium vivax vivapain-2 0.0709 0.4635 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Trypanosoma cruzi cysteine peptidase, putative 0.0709 0.4635 0.6649
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0733 0.4798 0.5
Giardia lamblia Hypothetical protein 0.0154 0.0871 0.0831
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0484 0.3109 0.3109
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0154 0.0871 0.1808
Echinococcus granulosus phd:f box containing protein 0.0048 0.0157 0.0208
Loa Loa (eye worm) hypothetical protein 0.0076 0.0343 0.0475
Plasmodium falciparum cysteine proteinase falcipain 3 0.0709 0.4635 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.015 0.0844 0.1196
Brugia malayi jmjC domain containing protein 0.0048 0.0157 0.0211
Loa Loa (eye worm) choline O-acetyltransferase 0.0198 0.1171 0.1664
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0379 0.2397 0.5139
Echinococcus granulosus chromobox protein 1 0.0152 0.086 0.1218
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0154 0.0871 0.0871
Loa Loa (eye worm) hypothetical protein 0.0085 0.0407 0.0567
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0448 0.0626
Toxoplasma gondii preprocathepsin c precursor, putative 0.0154 0.0871 0.1808
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0154 0.0871 0.1235
Toxoplasma gondii PHD-finger domain-containing protein 0.015 0.0844 0.1751
Schistosoma mansoni cathepsin B (C01 family) 0.0154 0.0871 0.1233
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0733 0.4798 0.5
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0109 0.0572 0.0804
Schistosoma mansoni jumonji domain containing protein 0.039 0.247 0.3531
Echinococcus granulosus histone lysine methyltransferase setb 0.0109 0.0572 0.0804
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0432 0.2757 0.3955
Schistosoma mansoni eyes absent homolog 0.0106 0.0551 0.0774
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0239 0.0239
Loa Loa (eye worm) ctsf protein 0.0709 0.4635 0.6643
Schistosoma mansoni cathepsin s 0.0225 0.1356 0.1931
Onchocerca volvulus Alhambra homolog 0.015 0.0844 0.1731
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0154 0.0871 0.0871
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0052 0.0184 0.0247
Plasmodium vivax hypothetical protein, conserved 0.015 0.0844 0.1751

Activities

Activity type Activity value Assay description Source Reference
I50 (binding) = 0.0000035 M Inhibition of Choline Acetyltransferase ChEMBL. 7932536
IC50 (binding) = 0.0000035 M Inhibition of Choline Acetyltransferase ChEMBL. 7932536

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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