Detailed information for compound 18321

Basic information

Technical information
  • TDR Targets ID: 18321
  • Name: 1-chloro-3-ethylpent-1-en-4-yn-3-ol
  • MW: 144.599 | Formula: C7H9ClO
  • H donors: 1 H acceptors: 1 LogP: 1.5 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(C#C)(/C=C/Cl)O
  • InChi: 1S/C7H9ClO/c1-3-7(9,4-2)5-6-8/h1,5-6,9H,4H2,2H3/b6-5+
  • InChiKey: ZEHYJZXQEQOSON-AATRIKPKSA-N  


Substructure search Similarity search

Network

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Synonyms

  • Aethyl-chlorvynol
  • Etchlorvinolo
  • Ethchlorovynol
  • Ethchlorvinol
  • Ethchlorvinyl
  • Ethchlorvynol
  • Ethclorvynol
  • Ethochlorvynol
  • Ethychlorvynol
  • (E)-1-chloro-3-ethylpent-1-en-4-yn-3-ol
  • (E)-1-chloro-3-ethyl-pent-1-en-4-yn-3-ol
  • (E)-1-chloro-3-ethyl-3-pent-1-en-4-ynol
  • 1-chloro-3-ethyl-pent-1-en-4-yn-3-ol
  • 113-18-8
  • D00704
  • Ethchlorvynol (JAN/USP/INN)
  • Placidyl (TN)
  • NSC 30372
  • beta-Chlorovinyl ethyl ethynyl carbinol
  • 1-Chloro-3-ethylpent-1-4-yn-3-ol
  • 3-(beta-Chlorovinyl)-1-pentyn-3-ol
  • 4-01-00-02315 (Beilstein Handbook Reference)
  • 5-Chloro-3-ethylpent-1-yn-4-en-3-ol
  • AI3-23721
  • BRN 1702245
  • DEA No. 2540
  • Etclorvinol [INN-Spanish]
  • Ethchlorvynol [USAN:BAN:INN]
  • Ethchlorvynolum [INN-Latin]
  • Ethyl beta-chlorovinyl ethynyl carbinol
  • HSDB 3079
  • C07833
  • beta-Chlorvinyl ethyl ethynyl carbinol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus fmrfamide receptor 0.0012 0.0002 0.0002
Schistosoma mansoni sodium/chloride dependent transporter 0.0089 0.1151 0.1645
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0106 0.0156
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.0342 0.0783
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Brugia malayi G-protein coupled receptor 0.0012 0.0002 0.0001
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0034 0.0331 0.9695
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0072 0.0896 0.1279
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0012 0.0002 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0002 0.0001
Brugia malayi hypothetical protein 0.0012 0.0002 0.0001
Brugia malayi G protein-coupled receptor 0.0012 0.0002 0.0001
Toxoplasma gondii sugar transporter ST3 0.0016 0.0064 0.0138
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0012 0.0002 0.0002
Toxoplasma gondii sugar transporter ST2 0.0016 0.0064 0.0138
Echinococcus granulosus solute carrier family 22 0.0016 0.0064 0.0064
Trypanosoma brucei glucose transporter, putative 0.0035 0.0348 0.6326
Plasmodium falciparum calcium-dependent protein kinase 3 0.0035 0.0342 0.0491
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0012 0.0002 0.0003
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0034 0.0331 0.0759
Schistosoma mansoni opsin-like receptor 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0079 0.1412
Loa Loa (eye worm) hypothetical protein 0.003 0.027 0.0618
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0002 0.0001
Schistosoma mansoni cpg binding protein 0.0036 0.036 0.0514
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Trypanosoma brucei glucose transporter, putative 0.0035 0.0348 0.6326
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0123 0.1657 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0012 0.0002 0.0002
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0348 0.6326
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0348 0.0798
Echinococcus granulosus 7tm_1 domain containing protein 0.0012 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0348 0.6326
Onchocerca volvulus 0.0012 0.0002 0.0003
Schistosoma mansoni glucose transport protein 0.0113 0.1504 0.2149
Schistosoma mansoni protein kinase 0.0035 0.0342 0.0487
Brugia malayi PHD-finger family protein 0.003 0.027 0.0403
Onchocerca volvulus 0.0016 0.0064 0.0226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0002 0.0001
Onchocerca volvulus 0.0012 0.0002 0.0003
Echinococcus granulosus survival motor neuron protein 1 0.0243 0.3435 0.3435
Plasmodium falciparum calcium-dependent protein kinase 4 0.0035 0.0342 0.0491
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0105 0.0239
Plasmodium falciparum protein kinase 7 0.0319 0.4561 0.6574
Onchocerca volvulus Alhambra homolog 0.003 0.027 0.0962
Brugia malayi Sugar transporter family protein 0.0016 0.0064 0.0095
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Echinococcus multilocularis conserved hypothetical protein 0.0674 0.9827 1
Onchocerca volvulus 0.0015 0.0053 0.0186
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0342 0.0342
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0012 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0064 0.0145
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0039 0.0415 0.0907
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Mycobacterium ulcerans integral membrane transport protein 0.0016 0.0064 0.3132
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0146 0.0876
Schistosoma mansoni lysyl-tRNA synthetase 0.0025 0.0203 0.0288
Schistosoma mansoni sugar transporter 0.0016 0.0064 0.009
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0002 0.0002
Chlamydia trachomatis lysine--tRNA ligase 0.0025 0.0203 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Schistosoma mansoni sugar transporter 0.0016 0.0064 0.009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus granulosus cpg binding protein 0.0036 0.036 0.036
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0016 0.0064 0.0066
Loa Loa (eye worm) PHD-finger family protein 0.003 0.027 0.0618
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Schistosoma mansoni cpg binding protein 0.0034 0.0332 0.0473
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0348 0.0798
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0079 0.1412
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0064 0.0145
Plasmodium falciparum calcium-dependent protein kinase 2 0.0035 0.0342 0.0491
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0079 0.2346
Echinococcus granulosus neuropeptide receptor 0.0012 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0305 0.4351 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0053 0.0078
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.027 0.059
Echinococcus multilocularis nibrin 0.0012 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0002 0.0001
Brugia malayi G-protein coupled receptor 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Brugia malayi putative neuropeptide receptor 0.0012 0.0002 0.0001
Echinococcus multilocularis General substrate transporter 0.0097 0.1268 0.1291
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0002 0.0001
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0016 0.0064 0.8149
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0106 0.0229
Loa Loa (eye worm) CXXC zinc finger family protein 0.0034 0.0332 0.076
Schistosoma mansoni hypothetical protein 0.0012 0.0002 0.0001
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0123 0.1657 1
Echinococcus multilocularis dnaJ subfamily B 0.0483 0.6992 0.7115
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0111 0.1474 0.8892
Schistosoma mansoni biogenic amine receptor 0.0012 0.0002 0.0001
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0053 0.0075
Schistosoma mansoni protein kinase 0.0035 0.0342 0.0487
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0392 0.0558
Onchocerca volvulus Neuropeptide F receptor homolog 0.0012 0.0002 0.0003
Leishmania major lysyl-tRNA synthetase, putative 0.0025 0.0203 0.285
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.1274 0.1274
Schistosoma mansoni neuropeptide receptor 0.0012 0.0002 0.0001
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0105 0.0107
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Plasmodium falciparum transporter, putative 0.0015 0.0053 0.0075
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0106 0.1901
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Schistosoma mansoni neuropeptide receptor 0.0012 0.0002 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0002 0.0002
Loa Loa (eye worm) sugar transporter 0.0016 0.0064 0.0145
Onchocerca volvulus 0.0012 0.0002 0.0003
Echinococcus granulosus 7TM GPCR rhodopsin 0.0012 0.0002 0.0002
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0182 0.2535 0.5557
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0002 0.0002
Toxoplasma gondii facilitative glucose transporter GT1 0.0113 0.1504 0.3295
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0053 0.012
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Plasmodium vivax glutathione reductase, putative 0.0049 0.055 0.0791
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0105 0.0156
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.2796 0.6425
Echinococcus granulosus allatostatin A receptor 0.0012 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Echinococcus multilocularis somatostatin receptor 0.0012 0.0002 0.0002
Schistosoma mansoni protein kinase 0.0035 0.0342 0.0487
Onchocerca volvulus 0.0016 0.0064 0.0226
Trypanosoma brucei glucose transporter, putative 0.0035 0.0348 0.6326
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Chlamydia trachomatis proline--tRNA ligase 0.0012 0.0006 0.0253
Echinococcus granulosus somatostatin receptor 0.0012 0.0002 0.0002
Echinococcus multilocularis GPCR, family 2 0.0019 0.0105 0.0107
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0014 0.0035 0.0078
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Plasmodium falciparum calcium-dependent protein kinase 5 0.0035 0.0342 0.0491
Giardia lamblia Hexose transporter 0.0016 0.0064 0.1912
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0002 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0079 0.1412
Brugia malayi major facilitator superfamily protein 0.0016 0.0064 0.0095
Loa Loa (eye worm) hypothetical protein 0.0034 0.0331 0.0759
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0039 0.0415 0.7535
Plasmodium vivax CDK-related protein kinase 6, putative 0.0479 0.6938 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0035 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus granulosus tachykinin peptides receptor 99D 0.0012 0.0002 0.0002
Trypanosoma cruzi hexose transporter 0.0035 0.0348 0.6326
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus granulosus neuropeptide receptor A26 0.0481 0.6966 0.6966
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0106 0.1901
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0782 0.1711
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0053 0.0075
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0079 0.0112
Loa Loa (eye worm) solute carrier family 6 member 4 0.0089 0.1151 0.2644
Brugia malayi Tachykinin-like peptides receptor 99D 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Plasmodium vivax amine transporter, putative 0.0015 0.0053 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0348 0.0798
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0015 0.0053 0.0053
Echinococcus multilocularis solute carrier family 22 0.0016 0.0064 0.0066
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0079 0.0111
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0064 0.0095
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0111 0.1474 0.8848
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0002 0.0001
Brugia malayi major facilitator superfamily protein 0.0016 0.0064 0.0095
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0012 0.0002 0.0001
Onchocerca volvulus 0.0012 0.0002 0.0003
Brugia malayi RE15519p 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus multilocularis dro:myosuppressin receptor 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0015 0.0053 0.0186
Schistosoma mansoni cpg binding protein 0.0036 0.036 0.0514
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.055 0.0791
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0012 0.0002 0.0002
Trichomonas vaginalis myo-inositol transporter, putative 0.0016 0.0064 0.0145
Onchocerca volvulus 0.0012 0.0002 0.0003
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.074 0.1698
Onchocerca volvulus 0.0016 0.0064 0.0226
Onchocerca volvulus 0.0016 0.0064 0.0226
Plasmodium falciparum proline--tRNA ligase 0.0039 0.0415 0.0596
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0443 0.0451
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0064 0.0145
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0079 1
Onchocerca volvulus 0.0016 0.0064 0.0226
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.005 0.0564 0.0805
Echinococcus multilocularis allatostatin A receptor 0.0012 0.0002 0.0002
Brugia malayi jmjC domain containing protein 0.0038 0.0392 0.0586
Loa Loa (eye worm) hypothetical protein 0.0125 0.1683 0.3867
Toxoplasma gondii sugar transporter ST1 0.0016 0.0064 0.0138
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0079 0.1412
Onchocerca volvulus 0.0016 0.0064 0.0226
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0053 0.0054
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus granulosus synaptic vesicle 2 protein 0.0016 0.0064 0.0064
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0004 0.0004
Onchocerca volvulus 0.0012 0.0002 0.0003
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0053 0.0075
Onchocerca volvulus 0.0012 0.0002 0.0003
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0348 0.6326
Echinococcus granulosus solute carrier family 22 0.0016 0.0064 0.0064
Onchocerca volvulus 0.0016 0.0064 0.0226
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0348 0.6326
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0342 0.0348
Echinococcus multilocularis peregrin 0.003 0.027 0.0275
Brugia malayi hypothetical protein 0.0012 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0019 0.0105 0.0149
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0564 0.0845
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0012 0.0002 0.0002
Brugia malayi AKH receptor 0.0012 0.0002 0.0001
Echinococcus multilocularis replication factor c subunit 1 0.0012 0.0001 0.0001
Schistosoma mansoni amine GPCR 0.0012 0.0002 0.0001
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0002 0.0002
Echinococcus multilocularis serotonin receptor 0.0012 0.0002 0.0002
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0053 0.0075
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0002 0.0001
Plasmodium falciparum phd finger protein, putative 0.003 0.027 0.0388
Onchocerca volvulus 0.0089 0.1151 0.4115
Echinococcus granulosus GPCR family 2 0.0019 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0053 0.0114
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Echinococcus granulosus Sugar transporter ERD6 protein 0.0016 0.0064 0.0064
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0002 0.0002
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0002 0.0002
Brugia malayi Cam kinase protein 1 0.0035 0.0342 0.0511
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.055 0.3048
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0113 0.1504 0.153
Trypanosoma brucei glucose transporter, putative 0.0035 0.0348 0.6326
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0019 0.0105 0.0149
Loa Loa (eye worm) hypothetical protein 0.0019 0.0105 0.0239
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0002 0.0002
Giardia lamblia Sugar-proton symporter 0.0016 0.0064 0.1912
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0127 0.0188
Echinococcus multilocularis calcium dependent protein kinase 0.0032 0.031 0.0316
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0053 0.0075
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0016 0.0064 0.115
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0106 0.1901
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0034 0.0331 0.0472
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0079 0.0116
Treponema pallidum prolyl-tRNA synthetase 0.0012 0.0006 0.0044
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0053 0.0078
Echinococcus granulosus g protein coupled receptor 0.0012 0.0002 0.0002
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0012 0.0002 0.0003
Echinococcus multilocularis lysyl tRNA synthetase 0.0025 0.0203 0.0206
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0415 0.7215
Plasmodium vivax lysine--tRNA ligase, putative 0.0025 0.0203 0.029
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0053 0.0075
Brugia malayi Melatonin receptor type 1A 0.0012 0.0002 0.0001
Echinococcus multilocularis solute carrier family 22 0.0016 0.0064 0.0066
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0392 0.0392
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0035 0.0342 0.0491
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0034 0.0331 0.0495
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0035 0.0342 0.0747
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0012 0.0006 0.0253
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0113 0.1504 0.1504
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0079 0.1412
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.055 0.1261
Brugia malayi hypothetical protein 0.0125 0.1683 0.2523
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0012 0.0002 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0305 0.4351 1
Schistosoma mansoni amine GPCR 0.0012 0.0002 0.0001
Echinococcus multilocularis survival motor neuron protein 1 0.0243 0.3435 0.3495
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0106 0.015
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0079 0.017
Trichomonas vaginalis glucose transporter, putative 0.0016 0.0064 0.0145
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0002 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0064 0.0095
Schistosoma mansoni neuropeptide receptor 0.0012 0.0002 0.0001
Plasmodium falciparum glutathione reductase 0.0049 0.055 0.0791
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0002 0.0001
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0443 0.0443
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0106 0.1901
Onchocerca volvulus 0.0016 0.0064 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0348 0.0798
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0025 0.0203 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0585 0.1343
Schistosoma mansoni amine GPCR 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.055 0.056
Echinococcus multilocularis G protein coupled receptor 139 0.0012 0.0002 0.0002
Brugia malayi Calcitonin receptor-like protein seb-1 0.0059 0.0702 0.1051
Brugia malayi jmjC domain containing protein 0.0097 0.1274 0.191
Brugia malayi hypothetical protein 0.0012 0.0002 0.0001
Onchocerca volvulus 0.0015 0.0053 0.0186
Entamoeba histolytica protein kinase, putative 0.0035 0.0342 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0034 0.0332 0.1183
Schistosoma mansoni sodium/chloride dependent transporter 0.0017 0.0085 0.012
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0106 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0064 0.0145
Brugia malayi Serotonin receptor 0.0012 0.0002 0.0001
Loa Loa (eye worm) norepinephrine transporter 0.0089 0.1151 0.2644
Onchocerca volvulus 0.0016 0.0064 0.0226
Brugia malayi Sugar transporter family protein 0.0016 0.0064 0.0095
Echinococcus granulosus serotonin receptor 0.0012 0.0002 0.0002
Trypanosoma cruzi hexose transporter, putative 0.0016 0.0064 0.115
Schistosoma mansoni alpha-1 adrenergic receptor 0.0012 0.0002 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0064 0.0145
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus granulosus g protein coupled receptor 0.0012 0.0002 0.0002
Toxoplasma gondii protein kinase, putative 0.0319 0.4561 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Plasmodium falciparum lysine--tRNA ligase 0.0025 0.0203 0.029
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.2796 0.6425
Schistosoma mansoni glucose transporter 0.0016 0.0064 0.009
Echinococcus multilocularis solute carrier family 22 0.0016 0.0064 0.0066
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0012 0.0002 0.0002
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0105 0.0156
Schistosoma mansoni hypothetical protein 0.003 0.027 0.0385
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0053 0.0075
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0348 0.6326
Toxoplasma gondii transporter, major facilitator family protein 0.0016 0.0064 0.0138
Onchocerca volvulus 0.0012 0.0002 0.0003
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0021 0.0146 0.0515
Plasmodium falciparum protein kinase 6 0.0479 0.6938 1
Trichomonas vaginalis glucosylceramidase, putative 0.0305 0.4351 1
Brugia malayi hypothetical protein 0.0153 0.2099 0.3147
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0113 0.1504 0.1504
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0079 0.008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0079 0.0295
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0079 0.017
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Plasmodium falciparum glutathione reductase 0.0017 0.0079 0.0112
Trypanosoma brucei sugar transporter, putative 0.0016 0.0064 0.115
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0035 0.0342 0.0747
Echinococcus granulosus neuropeptide FF receptor 2 0.0012 0.0002 0.0002
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0079 0.0178
Schistosoma mansoni amine GPCR 0.0012 0.0002 0.0001
Schistosoma mansoni glucose transport protein 0.0113 0.1504 0.2149
Trichomonas vaginalis glucosylceramidase, putative 0.0305 0.4351 1
Echinococcus granulosus peregrin 0.003 0.027 0.027
Onchocerca volvulus 0.0012 0.0002 0.0003
Trypanosoma brucei trypanothione reductase 0.0049 0.055 1
Brugia malayi hypothetical protein 0.0012 0.0002 0.0001
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0106 0.0258
Onchocerca volvulus 0.0016 0.0064 0.0226
Loa Loa (eye worm) hypothetical protein 0.0035 0.0342 0.0783
Brugia malayi PHD-finger family protein 0.0012 0.0002 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Trichomonas vaginalis glucosylceramidase, putative 0.0305 0.4351 1
Echinococcus multilocularis cpg binding protein 0.0036 0.036 0.0367
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Giardia lamblia Lysyl-tRNA synthetase 0.0025 0.0203 0.6103
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Plasmodium falciparum hexose transporter 0.0113 0.1504 0.2166
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0002 0.0002
Schistosoma mansoni sugar transporter 0.0016 0.0064 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0059 0.0702 0.161
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0089 0.1151 0.2644
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0053 0.012
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0002 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.2796 0.6425
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0392 0.0558
Brugia malayi hypothetical protein 0.0012 0.0002 0.0001
Echinococcus multilocularis serotonin transporter 0.0089 0.1151 0.1172
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0064 0.0095
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0025 0.0203 0.1217
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0106 0.0107
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.2956 0.6792
Echinococcus granulosus g-protein coupled receptor 0.0012 0.0002 0.0002
Treponema pallidum sodium- and chloride- dependent transporter 0.0089 0.1151 1
Leishmania major glucose transporter, lmgt3 0.0035 0.0348 0.5849
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Loa Loa (eye worm) glutathione reductase 0.0049 0.055 0.1261
Leishmania major glucose transporter/membrane transporter D2, putative 0.0035 0.0348 0.5849
Echinococcus granulosus nibrin 0.0012 0.0001 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0016 0.0064 0.3132
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0106 0.0107
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0113 0.1504 0.1504
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.1504 0.3454
Echinococcus multilocularis g-protein coupled receptor 0.0012 0.0002 0.0002
Echinococcus granulosus alpha 1A adrenergic receptor 0.0012 0.0002 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0106 0.0107
Schistosoma mansoni hypothetical protein 0.004 0.0426 0.0607
Echinococcus granulosus solute carrier family 22 0.0016 0.0064 0.0064
Onchocerca volvulus 0.0016 0.0064 0.0226
Brugia malayi larval opioid receptor 0.0012 0.0002 0.0001
Schistosoma mansoni opsin-like receptor 0.0012 0.0002 0.0001
Onchocerca volvulus Putative transporter 0.0016 0.0064 0.0226
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0012 0.0002 0.0002
Leishmania major glucose transporter, lmgt2 0.0035 0.0348 0.5849
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0105 0.0107
Toxoplasma gondii thioredoxin reductase 0.0049 0.055 0.1203
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0089 0.1151 0.1645
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0002 0.0001
Onchocerca volvulus 0.0012 0.0002 0.0003
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0053 0.0075
Brugia malayi GnHR receptor homolog 0.0012 0.0002 0.0001
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0113 0.1504 0.153
Trypanosoma cruzi sugar transporter, putative 0.0016 0.0064 0.115
Loa Loa (eye worm) hypothetical protein 0.0015 0.0053 0.012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0237 0.0542
Brugia malayi CXXC zinc finger family protein 0.0034 0.0332 0.0496
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.2796 0.6425
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0034 0.0331 0.0331
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0002 0.0002
Brugia malayi hypothetical protein 0.0016 0.0064 0.0095
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0053 0.012
Toxoplasma gondii hypothetical protein 0.0015 0.0053 0.0114
Onchocerca volvulus 0.005 0.0564 0.2014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0012 0.0002 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Schistosoma mansoni histamine h1 receptor 0.0012 0.0002 0.0001
Brugia malayi Serotonin receptor 0.0461 0.6667 1
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0034 0.0331 0.0337
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0113 0.2033
Schistosoma mansoni hypothetical protein 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Giardia lamblia PHD finger protein 15 0.003 0.027 0.8146
Brugia malayi Dopamine receptor 0.0012 0.0002 0.0001
Echinococcus granulosus neuropeptide s receptor 0.0481 0.6966 0.6966
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Schistosoma mansoni myosin xvIII 0.0012 0.0002 0.0001
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0016 0.0064 0.009
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0079 0.0112
Plasmodium vivax calcium-dependent protein kinase, putative 0.0035 0.0342 0.0491
Echinococcus granulosus g protein coupled receptor 0.0012 0.0002 0.0002
Leishmania major protein kinase, putative 0.0035 0.0342 0.5713
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0079 0.0112
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Trypanosoma brucei glucose transporter, putative 0.0035 0.0348 0.6326
Treponema pallidum NADH oxidase 0.0017 0.0079 0.0673
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0079 0.0079
Echinococcus granulosus serotonin transporter 0.0089 0.1151 0.1151
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0977 0.1396
Plasmodium vivax hexose transporter 0.0113 0.1504 0.2166
Entamoeba histolytica hypothetical protein 0.0025 0.0203 0.5917
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Onchocerca volvulus 0.0153 0.2099 0.7507
Loa Loa (eye worm) hypothetical protein 0.0089 0.1151 0.2644
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0079 0.3844
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0002 0.0002
Brugia malayi G protein-coupled receptor F59B2.13 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0034 0.0331 0.0495
Brugia malayi follicle stimulating hormone receptor 0.0012 0.0002 0.0001
Toxoplasma gondii hypothetical protein 0.0015 0.0053 0.0114
Echinococcus multilocularis synaptic vesicle 2 protein 0.0016 0.0064 0.0066
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0079 0.3844
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0342 0.0348
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0305 0.4351 0.6526
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0106 0.0107
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0106 0.0107
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0015 0.0053 0.0053
Schistosoma mansoni biogenic amine receptor 0.0012 0.0002 0.0001
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0415 0.7535
Plasmodium falciparum mitogen-activated protein kinase 2 0.0182 0.2535 0.3653
Plasmodium falciparum amino acid transporter, putative 0.0015 0.0053 0.0075
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0079 0.1412
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0039 0.0415 0.7535
Echinococcus multilocularis G-protein coupled receptor, putative 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0089 0.1151 0.2644
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Echinococcus granulosus sex peptide receptor 0.0012 0.0002 0.0002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0002 0.0002
Schistosoma mansoni growth hormone secretagogue receptor 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Giardia lamblia Prolyl-tRNA synthetase 0.0034 0.0331 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0034 0.0331 0.1994
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0342 0.0487
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0305 0.4351 1
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0002 0.0002
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0012 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0426 0.0637
Plasmodium vivax sugar transporter, putative 0.0016 0.0064 0.0091
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0342 0.0348
Echinococcus granulosus dro:myosuppressin receptor 0.0012 0.0002 0.0002
Trypanosoma brucei glucose transporter 2A 0.0035 0.0348 0.6326
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0012 0.0002 0.0002
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0035 0.0342 0.0783
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0079 0.1412
Brugia malayi hypothetical protein 0.0015 0.0053 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0211 0.2956 0.6792
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0002 0.0002
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0106 0.0229
Onchocerca volvulus Glucosylceramidase homolog 0.02 0.2796 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0111 0.1474 0.8848
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0012 0.0002 0.0001
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Schistosoma mansoni opsin-like receptor 0.0012 0.0002 0.0001
Echinococcus granulosus dnaJ subfamily B 0.0483 0.6992 0.6992
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0012 0.0002 0.0002
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0025 0.0203 0.0463
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0035 0.0342 0.0511
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0153 0.2099 0.4823
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0012 0.0002 0.0002
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0012 0.0002 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0064 0.0145
Echinococcus multilocularis orexin receptor type 2 0.0012 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Echinococcus multilocularis serotonin receptor 0.0012 0.0002 0.0002
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0015 0.0053 0.0054
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0342 0.0342
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0106 0.0848
Schistosoma mansoni neuropeptide receptor 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Schistosoma mansoni amine GPCR 0.0012 0.0002 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0002 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0079 0.1412
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0012 0.0002 0.0003
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0002 0.0002
Brugia malayi Dopamine receptor protein 1 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0053 0.012
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0053 0.012
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0012 0.0002 0.0001
Brugia malayi glutathione reductase 0.0049 0.055 0.0823
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0105 0.0105
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0053 0.0075
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0348 0.0798
Brugia malayi neuropeptide F receptor 0.0012 0.0002 0.0001
Trichomonas vaginalis sugar transport protein, putative 0.0016 0.0064 0.0145
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Schistosoma mansoni biogenic amine receptor 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Schistosoma mansoni lysyl-tRNA synthetase 0.0025 0.0203 0.0288
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0012 0.0017
Echinococcus granulosus calcium dependent protein kinase 0.0032 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Onchocerca volvulus 0.0012 0.0002 0.0003
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0079 0.0295
Echinococcus multilocularis neuropeptide FF receptor 2 0.0012 0.0002 0.0002
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0079 0.0112
Onchocerca volvulus 0.0016 0.0064 0.0226
Echinococcus granulosus lysyl tRNA synthetase 0.0025 0.0203 0.0203
Trypanosoma brucei glucose transporter, putative 0.0035 0.0348 0.6326
Schistosoma mansoni hypothetical protein 0.0113 0.1504 0.2149
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0025 0.0203 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0342 0.0348
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0079 0.1412
Schistosoma mansoni survival motor neuron protein 0.005 0.0564 0.0805
Schistosoma mansoni hypothetical protein 0.0019 0.0105 0.0149
Echinococcus granulosus neuropeptide receptor 0.0012 0.0002 0.0002
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0034 0.0331 0.0472
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0015 0.0053 0.2586
Onchocerca volvulus 0.0012 0.0002 0.0003
Trypanosoma brucei glucose transporter, putative 0.0035 0.0348 0.6326
Plasmodium falciparum calcium-dependent protein kinase 1 0.0035 0.0342 0.0491
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0053 0.0114
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0053 0.012
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0064 0.0145
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0098 0.0138
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0342 0.0342
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0002 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0002 0.0002
Echinococcus granulosus General substrate transporter 0.0097 0.1268 0.1268
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0305 0.4351 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0053 0.0114
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.027 0.059
Brugia malayi lysyl-tRNA synthetase 0.0025 0.0203 0.0302
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0079 0.0295
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0348 0.6326
Loa Loa (eye worm) hypothetical protein 0.0125 0.1683 0.3867
Mycobacterium tuberculosis Probable reductase 0.0111 0.1474 0.8848
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0002 0.0001
Leishmania major trypanothione reductase 0.0049 0.055 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0079 0.3844
Loa Loa (eye worm) hypothetical protein 0.004 0.0426 0.0976
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0012 0.0002 0.0001
Brugia malayi Dopamine receptor protein 2 0.0012 0.0002 0.0001
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0016 0.0064 0.0091
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0079 0.1412
Plasmodium vivax proline--tRNA ligase, putative 0.0039 0.0415 0.0596
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0053 0.0078
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0012 0.0002 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.2796 0.6425
Brugia malayi hypothetical protein 0.0012 0.0002 0.0001
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0106 0.0149
Brugia malayi hypothetical protein 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0053 0.012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Mycobacterium ulcerans sugar transporter 0.0016 0.0064 0.3132
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0113 0.1504 0.153
Plasmodium vivax hypothetical protein, conserved 0.003 0.027 0.0388
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0348 0.0798
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0025 0.0203 0.3672
Schistosoma mansoni glucose transport protein 0.0113 0.1504 0.2149
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0053 0.0053
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0002 0.0002
Echinococcus multilocularis sex peptide receptor 0.0012 0.0002 0.0002
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0348 0.0798
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0053 0.0054
Schistosoma mansoni hypothetical protein 0.0019 0.0105 0.0149
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0022 0.0157 0.0357
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0079 0.0178
Trypanosoma brucei glucose transporter 1E 0.0035 0.0348 0.6326
Trypanosoma brucei glucose transporter, putative 0.0035 0.0348 0.6326
Loa Loa (eye worm) serotonin transporter b 0.0089 0.1151 0.2644
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.027 0.027
Echinococcus multilocularis solute carrier family 22 0.0016 0.0064 0.0066
Loa Loa (eye worm) sugar transporter 0.0113 0.1504 0.3454
Loa Loa (eye worm) TYRA-2 protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0243 0.3435 0.7892
Echinococcus granulosus orexin receptor type 2 0.0012 0.0002 0.0002
Brugia malayi hypothetical protein 0.0016 0.0064 0.0095
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0079 1
Plasmodium falciparum thioredoxin reductase 0.0049 0.055 0.0791
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0035 0.0342 0.0491
Mycobacterium tuberculosis Probable oxidoreductase 0.0123 0.1657 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0079 0.1412
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0002 0.0002
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0106 0.024
Onchocerca volvulus 0.0012 0.0002 0.0003
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0079 0.0295
Schistosoma mansoni hypothetical protein 0.0012 0.0002 0.0001
Entamoeba histolytica protein kinase, putative 0.0035 0.0342 1
Brugia malayi isocitrate dehydrogenase 0.0019 0.0106 0.0156
Loa Loa (eye worm) hypothetical protein 0.0025 0.0203 0.0463
Onchocerca volvulus 0.0016 0.0064 0.0226
Brugia malayi neuropeptide F receptor 0.0012 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0002 0.0002
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0025 0.0203 0.3672
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0015 0.0053 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0002 0.0001
Onchocerca volvulus Huntingtin homolog 0.0125 0.1683 0.6018
Echinococcus multilocularis neuropeptide receptor A26 0.0481 0.6966 0.7089
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0064 0.0145
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0053 0.012
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Brugia malayi sulfakinin receptor protein 0.0012 0.0002 0.0001
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0012 0.0002 0.0002
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0059 0.0702 0.1051
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0012 0.0002 0.0002
Echinococcus granulosus peptide allatostatin:somatostatin 0.0012 0.0002 0.0002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0059 0.0702 0.161
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Schistosoma mansoni adenoreceptor 0.0012 0.0002 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0079 0.1412
Schistosoma mansoni sugar transporter 0.0016 0.0064 0.009
Brugia malayi hypothetical protein 0.0012 0.0002 0.0001
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0016 0.0064 0.3132
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.055 1
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.2796 0.6425
Brugia malayi Sugar transporter family protein 0.0113 0.1504 0.2254
Trypanosoma cruzi glucose transporter, putative 0.0016 0.0064 0.115
Brugia malayi hypothetical protein 0.0016 0.0064 0.0095
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0363 0.0369
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.027 0.0275
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.2796 0.6425
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0089 0.1151 0.1725
Echinococcus granulosus replication factor c subunit 1 0.0012 0.0001 0.0001
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0079 0.009
Brugia malayi hypothetical protein 0.0243 0.3435 0.515
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0111 0.1474 0.8848
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0079 0.3844
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0113 0.1504 0.1504
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0015 0.0053 0.0054
Brugia malayi Thioredoxin reductase 0.0049 0.055 0.0823
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0012 0.0002 0.0002
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0012 0.0017
Brugia malayi hypothetical protein 0.0012 0.0002 0.0001
Brugia malayi ORL1-like opioid receptor 0.0012 0.0002 0.0001
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0392 0.0897
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0012 0.0002 0.0001
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0015 0.0053 0.0054
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0002 0.0002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0079 0.1412
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0035 0.0342 0.6207
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0182 0.2535 0.3653
Toxoplasma gondii lysine-tRNA ligase 0.0025 0.0203 0.0442
Schistosoma mansoni neuropeptide f receptor 76f 0.0012 0.0002 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0021 0.0146 0.0515
Brugia malayi hypothetical protein 0.0012 0.0002 0.0001
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0123 0.1657 1
Echinococcus multilocularis neuropeptide s receptor 0.0481 0.6966 0.7089
Echinococcus granulosus G protein coupled receptor 139 0.0012 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0483 0.6992 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0064 0.0145
Onchocerca volvulus Huntingtin homolog 0.0125 0.1683 0.6018
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0113 0.1504 0.153
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0012 0.0002 0.0001
Plasmodium falciparum thioredoxin reductase 0.0017 0.0079 0.0112
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0035 0.0342 0.0747
Echinococcus granulosus solute carrier family 22 0.0016 0.0064 0.0064
Brugia malayi putative neuropeptide receptor NPR1 0.0012 0.0002 0.0001
Onchocerca volvulus 0.0016 0.0064 0.0226
Mycobacterium tuberculosis Probable dehydrogenase 0.0111 0.1474 0.8848
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.027 0.0385
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0035 0.0342 0.0783
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0012 0.0002 0.0002
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0053 0.0053
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.1274 0.1297
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0053 0.0053
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0034 0.0331 0.0759
Leishmania major glucose transporter, lmgt1 0.0035 0.0348 0.5849
Brugia malayi Bromodomain containing protein 0.003 0.027 0.0403
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0111 0.1474 0.8848
Schistosoma mansoni sodium-dependent amino acid transporter 0.0015 0.0053 0.0075
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0039 0.0415 0.7215
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0002 0.0001
Loa Loa (eye worm) melatonin receptor type 1A 0.0012 0.0002 0.0002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0053 0.0075
Onchocerca volvulus 0.0016 0.0064 0.0226
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0001
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0035 0.0342 0.0491
Onchocerca volvulus 0.0016 0.0064 0.0226

Activities

Activity type Activity value Assay description Source Reference
Cytochrome loss (functional) ND 0 % Percentage cytochrome P-450 loss from phenobarbital pretreated rats was measured in the presence of the NADPH after 10 min; Not detectable ChEMBL. 7143353
Cytochrome loss (functional) ND 0 % Percentage cytochrome P-450 loss from phenobarbital pretreated rats was measured in the presence of the NADPH after 20 min; Not detectable ChEMBL. 7143353
Cytochrome loss (functional) ND 0 % Percentage cytochrome P-450 loss from phenobarbital pretreated rats was measured in the presence of the NADPH after 30 min; Not detectable ChEMBL. 7143353
Cytochrome loss (functional) ND 0 % Percentage cytochrome P-450 loss from phenobarbital pretreated rats was measured in the presence of the Ethchlorvynol after 10 min; Not detectable ChEMBL. 7143353
Cytochrome loss (functional) ND 0 % Percentage cytochrome P-450 loss from phenobarbital pretreated rats was measured in the presence of the Ethchlorvynol after 20 min; Not detectable ChEMBL. 7143353
Cytochrome loss (functional) ND 0 % Percentage cytochrome P-450 loss from phenobarbital pretreated rats was measured in the presence of the Ethchlorvynol after 30 min; Not detectable ChEMBL. 7143353
Cytochrome loss (functional) = 4 % Percentage cytochrome P-450 loss from phenobarbital pretreated rats was measured in the presence of the oxygen after 20 min ChEMBL. 7143353
Cytochrome loss (functional) = 30 % Percentage cytochrome P-450 loss from phenobarbital pretreated rats was measured in the presence of oxygen and NADPH after 10 min ChEMBL. 7143353
Cytochrome loss (functional) = 35 % Percentage cytochrome P-450 loss from phenobarbital pretreated rats was measured in the presence of oxygen and NADPH after 20 min ChEMBL. 7143353
Cytochrome loss (functional) = 38 % Percentage cytochrome P-450 loss from phenobarbital pretreated rats was measured in the presence of oxygen and NADPH after 30 min ChEMBL. 7143353
Heme loss (functional) = 0.32 nM Heme loss from phenobarbital pretreated rats was measured in the presence of oxygen and NADPH after 20 min ChEMBL. 7143353
P-450 loss (functional) = 0.52 nM Cytochrome P-450 loss from phenobarbital pretreated rats was measured in the presence of oxygen and NADPH after 20 min ChEMBL. 7143353

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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