Detailed information for compound 1850683

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 333.336 | Formula: C17H19NO6
  • H donors: 3 H acceptors: 5 LogP: 2.38 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C([C@@]12CCC(C2(C)C)(C(=O)O1)C)Nc1cccc(c1O)C(=O)O
  • InChi: 1S/C17H19NO6/c1-15(2)16(3)7-8-17(15,24-14(16)23)13(22)18-10-6-4-5-9(11(10)19)12(20)21/h4-6,19H,7-8H2,1-3H3,(H,18,22)(H,20,21)/t16?,17-/m1/s1
  • InChiKey: XHDIHHKDNRURPQ-ZYMOGRSISA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0025 0.0012
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0017 0.0024 0.5
Trichomonas vaginalis rotamase, putative 0.0027 0.0053 0.0622
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0006 0.0006
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0057 0.0142 0.5
Plasmodium falciparum importin beta, putative 0.0023 0.0042 0.0224
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0056 0.0139 0.0139
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0291 0.0837 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0006 0.0006
Brugia malayi Probable ClpP-like protease 0.0087 0.023 0.0224
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0033 0.0388
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0291 0.0837 0.0837
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0006 0.0006
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0017 0.0024 0.0017
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0248 0.0708 0.0702
Trichomonas vaginalis set domain proteins, putative 0.0191 0.0539 0.6433
Leishmania major glycerol uptake protein, putative 0.0291 0.0837 1
Echinococcus granulosus survival motor neuron protein 1 0.019 0.0538 0.0538
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0018 0.0026 0.0303
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0145 0.0404 0.0398
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0087 0.023 0.5
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0024 0.0044 0.0044
Trichomonas vaginalis porcupine, putative 0.0291 0.0837 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0027
Trypanosoma cruzi glycerol uptake protein, putative 0.0291 0.0837 1
Brugia malayi diacylglycerol acyltransferase 0.0291 0.0837 0.0831
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0291 0.0837 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0048 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0057 0.0142 0.0136
Trypanosoma cruzi ISWI complex protein 0.0012 0.001 0.0105
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0025 0.0025
Entamoeba histolytica vacuolar protein sorting 26 0.0291 0.0837 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0006 0.0006
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0145 0.0404 0.479
Brugia malayi MBOAT family protein 0.0291 0.0837 0.0831
Onchocerca volvulus 0.0243 0.0695 0.8288
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0056 0.0139 0.0139
Trypanosoma cruzi importin beta-1 subunit, putative 0.0019 0.0029 0.0336
Trichomonas vaginalis conserved hypothetical protein 0.0291 0.0837 1
Trichomonas vaginalis hypothetical protein 0.0027 0.0054 0.0635
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0019 0.0029 0.0336
Loa Loa (eye worm) hhat protein 0.0291 0.0837 0.0831
Schistosoma mansoni importin beta-1 0.0023 0.0042 0.0042
Plasmodium vivax ataxin-2 like protein, putative 0.002 0.0033 0.0117
Schistosoma mansoni microtubule-associated protein tau 0.0766 0.2245 0.2245
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0291 0.0837 0.0837
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0291 0.0837 0.0837
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0006 0.0006
Loa Loa (eye worm) PHD-finger family protein 0.0017 0.0022 0.0016
Brugia malayi Hhat protein 0.0291 0.0837 0.0831
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0025 0.0285
Schistosoma mansoni jumonji domain containing protein 0.0065 0.0167 0.0167
Trichomonas vaginalis ran, putative 0.0017 0.0024 0.0274
Onchocerca volvulus Huntingtin homolog 0.0099 0.0266 0.3122
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0006 0.0006
Brugia malayi hypothetical protein 0.0056 0.0139 0.0133
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0024 0.0044 0.0044
Echinococcus multilocularis zinc finger protein 0.0016 0.002 0.002
Echinococcus multilocularis lysine specific demethylase 5A 0.0065 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0291 0.0837 0.0831
Entamoeba histolytica hypothetical protein, conserved 0.0291 0.0837 1
Brugia malayi hypothetical protein 0.0243 0.0695 0.0689
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0025 0.0018
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0057 0.0142 0.4744
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0026 0.0051 0.05
Trypanosoma cruzi glycerol uptake protein, putative 0.0291 0.0837 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0171 0.0171
Echinococcus multilocularis expressed protein 0.0027 0.0053 0.0053
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0291 0.0837 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0006 0.0006
Trichomonas vaginalis importin beta-1, putative 0.0019 0.0029 0.0336
Brugia malayi hypothetical protein 0.019 0.0538 0.0532
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0026 0.0051 0.0599
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0017 0.0024 0.0024
Leishmania major importin beta-1 subunit, putative 0.0019 0.0029 0.0233
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0291 0.0837 0.0837
Schistosoma mansoni ran 0.0017 0.0024 0.0024
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0158 0.0442 0.5278
Schistosoma mansoni methyl-cpg binding protein mbd 0.0014 0.0014 0.0014
Brugia malayi jmjC domain containing protein 0.0017 0.0025 0.0018
Brugia malayi Bromodomain containing protein 0.006 0.0152 0.0146
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0014 0.0014 0.0014
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0017 0.0024 0.0274
Echinococcus granulosus zinc finger protein 0.3088 0.9136 0.9136
Leishmania major glycerol uptake protein, putative 0.0291 0.0837 1
Leishmania major hypothetical protein, conserved 0.0291 0.0837 1
Trichomonas vaginalis transmembrane protein nessy, putative 0.0291 0.0837 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0087 0.023 0.5
Loa Loa (eye worm) hypothetical protein 0.0031 0.0065 0.0058
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0025 0.0025
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0291 0.0837 0.0837
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0048 0.0116 0.0116
Loa Loa (eye worm) hhat protein 0.0291 0.0837 0.0831
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0029 0.0029
Trypanosoma cruzi GUP1, putative 0.0291 0.0837 1
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0291 0.0837 1
Schistosoma mansoni coup transcription factor 0.0011 0.0006 0.0006
Echinococcus multilocularis sterol O acyltransferase 1 0.0291 0.0837 0.0837
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0291 0.0837 0.0837
Trypanosoma brucei PAB1-binding protein , putative 0.002 0.0033 0.0388
Loa Loa (eye worm) hypothetical protein 0.0291 0.0837 0.0831
Echinococcus granulosus peptidase Clp S14 family 0.0057 0.0142 0.0142
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0291 0.0837 0.0837
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0017 0.0024 0.0274
Schistosoma mansoni ran 0.0017 0.0024 0.0024
Onchocerca volvulus 0.0291 0.0837 1
Loa Loa (eye worm) hypothetical protein 0.0243 0.0695 0.0689
Schistosoma mansoni hypothetical protein 0.0039 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0034 0.0075 0.0069
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0025 0.0012
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0006 0.0006
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0025 0.0285
Toxoplasma gondii hypothetical protein 0.0291 0.0837 1
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0025 0.0025
Trypanosoma brucei importin beta-1 subunit, putative 0.0023 0.0042 0.0491
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0024 0.0044 0.0253
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0018
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0017 0.0024 0.0274
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0006 0.0006
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.003 0.0062 0.0467
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0087 0.023 0.2543
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0087 0.023 0.2177
Trypanosoma brucei ISWI complex protein 0.0012 0.001 0.0105
Toxoplasma gondii LsmAD domain-containing protein 0.002 0.0033 0.0117
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0006 0.0006
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0006 0.0006
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0025 0.0025
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0025 0.0025
Loa Loa (eye worm) bromodomain containing protein 0.0014 0.0015 0.0009
Echinococcus granulosus importin subunit beta 1 0.0023 0.0042 0.0042
Leishmania major GTP-binding protein, putative 0.0017 0.0024 0.0171
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0006 0.0006
Echinococcus granulosus microtubule associated protein 2 0.0766 0.2245 0.2245
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0025 0.0025
Loa Loa (eye worm) MBOAT family protein 0.3379 1 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0017 0.0024 0.0017
Brugia malayi MBOAT family protein 0.0291 0.0837 0.0831
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.3379 1 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0038 0.0085 0.0085
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0291 0.0837 0.0837
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0006 0.0006
Trypanosoma cruzi ISWI complex protein 0.0012 0.001 0.0105
Brugia malayi RNA, U transporter 1 0.0066 0.0169 0.0163
Brugia malayi jmjC domain containing protein 0.0017 0.0025 0.0018
Loa Loa (eye worm) hypothetical protein 0.0158 0.0442 0.0436
Echinococcus multilocularis microtubule associated protein 2 0.0766 0.2245 0.2245
Brugia malayi jmjC domain containing protein 0.0017 0.0025 0.0018
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0018 0.0027 0.0027
Echinococcus multilocularis zinc finger protein 0.3088 0.9136 0.9136
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0291 0.0837 0.0831
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0291 0.0837 0.0837
Schistosoma mansoni hypothetical protein 0.0248 0.0708 0.0708
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.3379 1 1
Loa Loa (eye worm) hypothetical protein 0.0291 0.0837 0.0831
Brugia malayi MBOAT family protein 0.0291 0.0837 0.0831
Echinococcus granulosus o acyltransferase membrane bound domain 0.0291 0.0837 0.0837
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0085 0.0085
Loa Loa (eye worm) MBOAT family protein 0.0291 0.0837 0.0831
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0006 0.0006
Brugia malayi hypothetical protein 0.0099 0.0266 0.026
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0026 0.0051 0.0599
Schistosoma mansoni rotamase 0.0027 0.0053 0.0053
Brugia malayi Importin beta-1 subunit 0.0023 0.0042 0.0036
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0027 0.0053 0.0047
Schistosoma mansoni hypothetical protein 0.0291 0.0837 0.0837
Brugia malayi hypothetical protein 0.0013 0.0012 0.0006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0006 0.0006
Brugia malayi jmjC domain containing protein 0.0017 0.0025 0.0018
Echinococcus multilocularis survival motor neuron protein 1 0.019 0.0538 0.0538
Schistosoma mansoni hypothetical protein 0.0324 0.0936 0.0936
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0006 0.0006
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0291 0.0837 1
Loa Loa (eye worm) hypothetical protein 0.019 0.0538 0.0532
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0006 0.0006
Loa Loa (eye worm) MBOAT family protein 0.0291 0.0837 0.0831
Loa Loa (eye worm) hypothetical protein 0.0099 0.0266 0.026
Echinococcus granulosus o acyltransferase membrane bound domain 0.0291 0.0837 0.0837
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0025 0.0018
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0006 0.0006
Echinococcus granulosus expressed protein 0.0027 0.0053 0.0053
Onchocerca volvulus 0.0024 0.0044 0.0458
Echinococcus multilocularis geminin 0.0324 0.0936 0.0936
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0087 0.023 0.2543
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0025 0.0025
Brugia malayi Bromodomain containing protein 0.0031 0.0064 0.0058
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0291 0.0837 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0026 0.0051 0.0599
Echinococcus granulosus geminin 0.0324 0.0936 0.0936
Brugia malayi jmjC domain containing protein 0.0067 0.0171 0.0165
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0006 0.0006
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0027 0.0053 0.0047
Schistosoma mansoni hypothetical protein 0.0324 0.0936 0.0936
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0171 0.0165
Plasmodium vivax JmjC domain containing protein 0.0017 0.0025 0.0012
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0025 0.0025
Schistosoma mansoni tsg101-related 0.0047 0.0111 0.0111
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0087 0.023 0.5
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0026 0.0051 0.0599
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0056 0.0139 0.0133
Loa Loa (eye worm) hypothetical protein 0.0038 0.0085 0.0079
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0087 0.023 1
Onchocerca volvulus Huntingtin homolog 0.0099 0.0266 0.3122
Entamoeba histolytica hypothetical protein 0.0291 0.0837 1
Echinococcus multilocularis peptidase Clp (S14 family) 0.0057 0.0142 0.0142
Leishmania major glycerol uptake protein, putative 0.0291 0.0837 1
Brugia malayi Pre-SET motif family protein 0.0024 0.0044 0.0038
Echinococcus granulosus histone lysine methyltransferase setb 0.0038 0.0085 0.0085
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0057 0.0142 0.5
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0018 0.0026 0.0303
Brugia malayi Pre-SET motif family protein 0.0168 0.047 0.0464
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0168 0.047 0.0464
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0018
Echinococcus granulosus o acyltransferase membrane bound domain 0.0291 0.0837 0.0837
Plasmodium vivax importin-beta 2, putative 0.0023 0.0042 0.0224
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0023 0.0042 0.0042
Schistosoma mansoni bromodomain containing protein 0.0051 0.0124 0.0124
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0033 0.0117
Leishmania major glycerol uptake protein, putative 0.0291 0.0837 1
Entamoeba histolytica hypothetical protein 0.0019 0.0029 0.0336
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0025 0.0012
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0029 0.0059 0.0059
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0291 0.0837 0.0837
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0291 0.0837 0.0837
Loa Loa (eye worm) hypothetical protein 0.0099 0.0266 0.026
Trypanosoma brucei importin beta-1 subunit, putative 0.0023 0.0042 0.0491
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0006 0.0006
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0291 0.0837 0.0831
Toxoplasma gondii hypothetical protein 0.003 0.0062 0.0467
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0087 0.023 0.023
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0291 0.0837 0.0837
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0085 0.0085
Echinococcus granulosus GTP binding nuclear protein Ran 0.0017 0.0024 0.0024
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0029 0.0059 0.0059
Leishmania major hypothetical protein, conserved 0.002 0.0033 0.0286
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0025 0.0025
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0291 0.0837 1
Brugia malayi N-terminal motif family protein 0.0145 0.0404 0.0398
Brugia malayi jmjC domain containing protein 0.0065 0.0167 0.016
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0087 0.023 0.5
Leishmania major glycerol uptake protein, putative 0.0291 0.0837 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0087 0.023 0.2543
Leishmania major hypothetical protein, conserved 0.0018 0.0026 0.02
Trypanosoma cruzi glycerol uptake protein, putative 0.0291 0.0837 1
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0006 0.0006
Plasmodium vivax SET domain protein, putative 0.0024 0.0044 0.0253
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0006 0.0006
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0006 0.0006
Treponema pallidum alginate O-acetylation protein (algI) 0.0291 0.0837 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0018 0.0027 0.0027
Toxoplasma gondii HEAT repeat-containing protein 0.0023 0.0042 0.0224
Echinococcus granulosus lysine specific demethylase 5A 0.0067 0.0171 0.0171
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0291 0.0837 0.0837
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0025 0.0285
Trypanosoma brucei glycerol uptake protein, putative 0.0291 0.0837 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0087 0.023 0.0224
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0039 0.0088 0.0082
Schistosoma mansoni zinc finger protein 0.0016 0.002 0.002
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0087 0.023 0.023
Onchocerca volvulus 0.0039 0.0088 0.0986
Echinococcus granulosus methyl CpG binding domain protein 2 0.0014 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0053 0.0622
Schistosoma mansoni methyl-cpg binding protein mbd 0.0014 0.0014 0.0014
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0065 0.0167 0.0167
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0087 0.023 0.5
Brugia malayi PHD-finger family protein 0.002 0.0032 0.0026
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0006 0.0006
Trypanosoma cruzi GUP1, putative 0.0291 0.0837 1
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0291 0.0837 0.0837
Brugia malayi MBOAT family protein 0.0291 0.0837 0.0831
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0291 0.0837 0.0837
Echinococcus granulosus fetal alzheimer antigen falz 0.0018 0.0027 0.0027
Echinococcus granulosus zinc finger protein 0.0016 0.002 0.002
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0019 0.0029 0.0336
Echinococcus granulosus phd:f box containing protein 0.0017 0.0025 0.0025
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0291 0.0837 0.0837
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0018
Schistosoma mansoni survival motor neuron protein 0.0039 0.0088 0.0088
Schistosoma mansoni zinc finger protein 0.3379 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0291 0.0837 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0006 0.0006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0171 0.0171
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0025 0.0025
Schistosoma mansoni sterol O-acyltransferase 1 0.0291 0.0837 0.0837
Echinococcus granulosus sterol O acyltransferase 1 0.0291 0.0837 0.0837
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0065 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0036
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0653 0.191 0.191
Leishmania major hypothetical protein, conserved 0.0017 0.0025 0.0182
Onchocerca volvulus 0.0191 0.0539 0.6409
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0022
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0033 0.0388
Trypanosoma brucei glycerol uptake protein, putative 0.0291 0.0837 1
Schistosoma mansoni tsg101-related 0.0038 0.0086 0.0086
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0038 0.0086 0.1019
Loa Loa (eye worm) hypothetical protein 0.0291 0.0837 0.0831
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0024 0.0044 0.0044
Trichomonas vaginalis rotamase, putative 0.0026 0.0051 0.0599
Brugia malayi hypothetical protein 0.002 0.0033 0.0027
Echinococcus multilocularis importin subunit beta 1 0.0023 0.0042 0.0042
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0087 0.023 0.2543
Schistosoma mansoni tsg101-related 0.0047 0.0111 0.0111
Schistosoma mansoni hypothetical protein 0.0012 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0033 0.007 0.0064
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0033 0.0117
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0006 0.0006
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0025 0.0025
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0029 0.0029
Entamoeba histolytica Ran family GTPase 0.0017 0.0024 0.0274
Schistosoma mansoni zinc finger protein 0.0012 0.001 0.001
Schistosoma mansoni peptidase Clp (S14 family) 0.0087 0.023 0.023
Toxoplasma gondii peptidylprolyl isomerase 0.0026 0.0051 0.0335
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0158 0.0442 0.5278
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0291 0.0837 0.0837
Echinococcus granulosus snurportin 1 0.0248 0.0708 0.0708
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0025 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0291 0.0837 1
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.003 0.0062 0.0467
Echinococcus multilocularis snurportin 1 0.0248 0.0708 0.0708

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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