Detailed information for compound 1896765

Basic information

Technical information
  • TDR Targets ID: 1896765
  • Name: 1-[[(2R)-2,3-dihydro-1,4-benzodioxin-2-yl]met hyl]piperidine
  • MW: 233.306 | Formula: C14H19NO2
  • H donors: 0 H acceptors: 0 LogP: 2.59 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: C1CCN(CC1)C[C@@H]1COc2c(O1)cccc2
  • InChi: 1S/C14H19NO2/c1-4-8-15(9-5-1)10-12-11-16-13-6-2-3-7-14(13)17-12/h2-3,6-7,12H,1,4-5,8-11H2/t12-/m1/s1
  • InChiKey: LYKMMUBOEFYJQG-GFCCVEGCSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Adrenergic receptor alpha Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Adrenergic receptor alpha   515 aa 429 aa 20.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0036 0.0081 0.0112
Brugia malayi Dopamine receptor protein 2 0.0036 0.008 0.0109
Brugia malayi hypothetical protein 0.0036 0.008 0.0109
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0081 0.0081
Schistosoma mansoni opsin-like receptor 0.0036 0.008 0.0109
Echinococcus multilocularis neuropeptide Y receptor 0.0036 0.008 0.008
Onchocerca volvulus 0.0036 0.008 0.0456
Schistosoma mansoni transient receptor potential channel 0.0064 0.0575 0.079
Toxoplasma gondii proteasome subunit beta type, putative 0.016 0.2249 0.9948
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0083 0.0899 0.1234
Toxoplasma gondii thioredoxin reductase 0.0085 0.0943 0.417
Echinococcus granulosus somatostatin receptor 0.0036 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0012 0.0054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0012 0.0054
Plasmodium falciparum serine repeat antigen 7 0.0032 0.0012 0.0054
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0081 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0081 0.0234
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0032 0.0012 0.0054
Echinococcus granulosus proteasome prosome macropain 0.016 0.2249 0.2249
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0041 0.017 0.0234
Echinococcus granulosus inhibitor of apoptosis protein 0.0131 0.1746 0.1746
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0012 0.0017
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.2308 0.2308
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0032 0.0012 0.0017
Toxoplasma gondii cathepsin CPC2 0.0032 0.0012 0.0054
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0124 0.1625 0.7224
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0077 0.0798 0.3527
Brugia malayi hypothetical protein 0.0035 0.0069 0.0094
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Echinococcus multilocularis neuropeptide receptor 0.0036 0.008 0.008
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0164 0.2308 0.3168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0195 0.2855 0.8825
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0012 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Echinococcus multilocularis g protein coupled receptor 0.0036 0.008 0.008
Toxoplasma gondii cathepsin CPC1 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Giardia lamblia Cathepsin L precursor 0.0032 0.0012 0.0054
Schistosoma mansoni cathepsin B (C01 family) 0.0032 0.0012 0.0017
Leishmania major cysteine peptidase A (CPA) 0.0083 0.0899 0.3974
Onchocerca volvulus 0.0083 0.0899 0.5147
Giardia lamblia Cathepsin L precursor 0.0032 0.0012 0.0054
Plasmodium vivax unspecified product 0.0032 0.0012 0.0054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0899 0.3974
Echinococcus granulosus hypothetical protein 0.0036 0.008 0.008
Schistosoma mansoni biogenic amine (5HT) receptor 0.0036 0.008 0.0109
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0098 0.0134
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0032 0.0012 0.0017
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0124 0.1625 0.7186
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0034 0.0047 0.0208
Schistosoma mansoni alpha-glucosidase 0.0141 0.191 0.2622
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Giardia lamblia Cysteine protease 0.0032 0.0012 0.0054
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0098 0.0433
Loa Loa (eye worm) cathepsin B 0.0161 0.2261 0.3104
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0081 0.0112
Brugia malayi Immunoglobulin I-set domain containing protein 0.0062 0.0529 0.0726
Leishmania major cathepsin L-like protease 0.0083 0.0899 0.3974
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0036 0.008 0.008
Leishmania major cathepsin L-like protease 0.0083 0.0899 0.3974
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Giardia lamblia Cathepsin L-like protease 0.0032 0.0012 0.0054
Giardia lamblia Cysteine protease 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0062 0.0529 0.0726
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0124 0.1625 0.7186
Loa Loa (eye worm) hypothetical protein 0.0036 0.0081 0.0112
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Mycobacterium tuberculosis Conserved protein 0.0036 0.0081 0.0234
Onchocerca volvulus 0.0034 0.0047 0.027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.008 0.008
Echinococcus granulosus cathepsin l1 0.0083 0.0899 0.0899
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0195 0.2855 0.8194
Loa Loa (eye worm) cysteine protease 0.0083 0.0899 0.1234
Leishmania major trypanothione reductase 0.0085 0.0943 0.417
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0267 0.4114 0.5649
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0036 0.008 0.0109
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0217 0.3236 1
Trypanosoma cruzi trypanothione reductase, putative 0.0085 0.0943 0.1294
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0899 0.3974
Loa Loa (eye worm) hypothetical protein 0.0061 0.0514 0.0706
Giardia lamblia Cathepsin B precursor 0.0161 0.2261 1
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0034 0.0047 0.0208
Brugia malayi cathepsin B-like cysteine proteinase 0.0448 0.7284 1
Brugia malayi hypothetical protein 0.0036 0.008 0.0109
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0036 0.008 0.0109
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0012 0.0017
Plasmodium falciparum serine repeat antigen 2 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0062 0.0529 0.0529
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0081 0.0112
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0032 0.0012 0.0017
Onchocerca volvulus 0.0036 0.008 0.0456
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0062 0.0529 0.0529
Leishmania major cathepsin L-like protease 0.0083 0.0899 0.3974
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0034 0.0047 0.0047
Echinococcus multilocularis g protein coupled receptor 0.0036 0.008 0.008
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0081 0.036
Plasmodium falciparum proteasome subunit beta type-5 0.016 0.2249 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0036 0.008 0.0109
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0012 0.0017
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0195 0.2855 0.8194
Onchocerca volvulus 0.0036 0.008 0.0456
Loa Loa (eye worm) TYRA-2 protein 0.0036 0.008 0.0109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0899 0.3974
Mycobacterium ulcerans hypothetical protein 0.0036 0.0081 0.0362
Brugia malayi beta-lactamase family protein 0.0036 0.0081 0.0112
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Giardia lamblia Proteasome subunit beta type 1 0.0124 0.1625 0.7186
Echinococcus granulosus cathepsin L 0.0032 0.0012 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.0083 0.0899 0.3995
Trypanosoma cruzi cysteine protease, putative 0.0032 0.0012 0.0017
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0034 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Trypanosoma brucei glucosidase, putative 0.0036 0.0084 0.0372
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0032 0.0012 0.0054
Brugia malayi Cathepsin L-like precursor 0.0083 0.0899 0.1234
Brugia malayi neuropeptide F receptor 0.0036 0.008 0.0109
Entamoeba histolytica hypothetical protein 0.0035 0.0069 0.0306
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0012 0.0054
Giardia lamblia Cysteine protease 0.0032 0.0012 0.0054
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0085 0.0943 0.2706
Entamoeba histolytica cysteine proteinase 2 0.0032 0.0012 0.0054
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0515 0.229
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0012 0.0054
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0124 0.1625 0.2231
Brugia malayi glutathione reductase 0.0085 0.0943 0.1294
Entamoeba histolytica hypothetical protein 0.0032 0.0012 0.0054
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0032 0.0012 0.0054
Schistosoma mansoni amine GPCR 0.0436 0.7069 0.9705
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0084 0.0372
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0083 0.0899 0.1234
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Schistosoma mansoni amine GPCR 0.0036 0.008 0.0109
Schistosoma mansoni hypothetical protein 0.0036 0.008 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.0081 0.0112
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0036 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0899 0.3974
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0515 0.229
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0084 0.0372
Schistosoma mansoni inositol monophosphatase 0.0037 0.0098 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0012 0.0054
Entamoeba histolytica hypothetical protein 0.0035 0.0069 0.0306
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.016 0.2249 0.3088
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0036 0.008 0.008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.1027 0.1411
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0098 0.0435
Echinococcus granulosus cathepsin l1 0.0083 0.0899 0.0899
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0131 0.1746 0.1746
Trypanosoma brucei Aminopeptidase M1, putative 0.0034 0.0047 0.0208
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.008 0.008
Echinococcus multilocularis fmrfamide receptor 0.0036 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0012 0.0054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.008 0.0109
Echinococcus granulosus neuropeptide receptor 0.0036 0.008 0.008
Brugia malayi Cathepsin L-like precursor 0.0083 0.0899 0.1234
Echinococcus granulosus g protein coupled receptor 0.0036 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.008 0.008
Echinococcus granulosus short transient receptor potential channel 6 0.0064 0.0575 0.0575
Echinococcus multilocularis neuropeptide receptor A26 0.0036 0.008 0.008
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0036 0.008 0.008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.1027 0.1027
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0036 0.008 0.008
Brugia malayi sulfakinin receptor protein 0.0036 0.008 0.0109
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0036 0.008 0.008
Echinococcus granulosus 7TM GPCR rhodopsin 0.0036 0.008 0.008
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Onchocerca volvulus 0.0036 0.008 0.0456
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0448 0.7284 1
Echinococcus granulosus g protein coupled receptor 0.0036 0.008 0.008
Brugia malayi cathepsin Z-like cysteine proteinase 0.0032 0.0012 0.0017
Loa Loa (eye worm) fibroinase 0.0083 0.0899 0.1234
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0032 0.0012 0.0054
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0036 0.008 0.0456
Echinococcus granulosus G protein coupled receptor 139 0.0036 0.008 0.008
Echinococcus multilocularis G protein coupled receptor 139 0.0036 0.008 0.008
Brugia malayi hypothetical protein 0.006 0.0498 0.0684
Brugia malayi hypothetical protein 0.0036 0.008 0.0109
Brugia malayi larval opioid receptor 0.0036 0.008 0.0109
Brugia malayi Cathepsin L-like precursor 0.0083 0.0899 0.1234
Echinococcus multilocularis cathepsin L 0.0032 0.0012 0.0012
Plasmodium falciparum thioredoxin reductase 0.0085 0.0943 0.4192
Toxoplasma gondii cathepsin B 0.0161 0.2261 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0081 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0899 0.3974
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0084 0.0115
Onchocerca volvulus Deterin homolog 0.0131 0.1746 1
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0032 0.0012 0.0017
Loa Loa (eye worm) aminopeptidase N 0.0034 0.0047 0.0065
Brugia malayi Melatonin receptor type 1A 0.0036 0.008 0.0109
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.016 0.2249 0.3088
Echinococcus granulosus neuropeptide s receptor 0.0036 0.008 0.008
Giardia lamblia Cathepsin L precursor 0.0032 0.0012 0.0054
Onchocerca volvulus 0.0083 0.0899 0.5147
Mycobacterium tuberculosis Conserved protein 0.0036 0.0081 0.0234
Onchocerca volvulus Cell death protein 3 homolog 0.006 0.0498 0.2855
Trypanosoma brucei trypanothione reductase 0.0085 0.0943 0.417
Schistosoma mansoni hypothetical protein 0.0036 0.008 0.0109
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0032 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0077 0.0798 0.1095
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0124 0.1625 0.2231
Onchocerca volvulus 0.0036 0.0081 0.0467
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0077 0.0798 0.3527
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.1027 0.1027
Echinococcus multilocularis short transient receptor potential channel 6 0.0064 0.0575 0.0575
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0034 0.0047 0.0047
Echinococcus granulosus fmrfamide receptor 0.0036 0.008 0.008
Brugia malayi Inositol-1 0.0037 0.0098 0.0134
Echinococcus granulosus cathepsin l cysteine peptidase 0.0083 0.0899 0.0899
Brugia malayi Glycosyl hydrolases family 31 protein 0.0164 0.2308 0.3168
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Echinococcus granulosus transient receptor potential gamma protein 0.0097 0.1145 0.1145
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0899 0.3974
Giardia lamblia Proteasome subunit beta type 5 precursor 0.016 0.2249 0.9948
Echinococcus granulosus TRP transient receptor potential channel 0.0036 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0161 0.2261 1
Schistosoma mansoni hypothetical protein 0.0036 0.008 0.0109
Trypanosoma cruzi major cysteine proteinase, putative 0.0032 0.0012 0.0017
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0032 0.0012 0.0054
Echinococcus multilocularis aminopeptidase N 0.0034 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0131 0.1746 0.2397
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0515 0.0515
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0083 0.0899 0.3974
Brugia malayi hypothetical protein 0.0036 0.008 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Leishmania major cathepsin L-like protease 0.0083 0.0899 0.3974
Loa Loa (eye worm) G-protein coupled receptor 0.0036 0.008 0.0109
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0081 0.0362
Echinococcus multilocularis cathepsin L cysteine protease 0.0083 0.0899 0.0899
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0098 0.0433
Loa Loa (eye worm) G-protein coupled receptor 0.0036 0.008 0.0109
Brugia malayi hypothetical protein 0.0036 0.008 0.0109
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0036 0.008 0.0109
Echinococcus multilocularis allatostatin A receptor 0.0036 0.008 0.008
Plasmodium vivax proteasome subunit beta type-5, putative 0.016 0.2249 1
Loa Loa (eye worm) proteasome subunit beta type 1 0.0124 0.1625 0.2231
Brugia malayi hypothetical protein 0.0036 0.008 0.0109
Echinococcus multilocularis dro:myosuppressin receptor 0.0036 0.008 0.008
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0081 0.0234
Schistosoma mansoni neuropeptide receptor 0.0036 0.008 0.0109
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0124 0.1625 0.1625
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0081 0.036
Brugia malayi proteasome subunit beta type 1 0.0124 0.1625 0.2231
Schistosoma mansoni cathepsin S (C01 family) 0.0032 0.0012 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0899 0.3974
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0034 0.0047 0.0208
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0032 0.0012 0.0054
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0032 0.0012 0.0017
Echinococcus multilocularis cysteine protease 0.0083 0.0899 0.0899
Echinococcus granulosus neuropeptides capa receptor 0.0036 0.008 0.008
Giardia lamblia Cathepsin L precursor 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0515 0.1478
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.008 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.008 0.0109
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0515 0.0707
Leishmania major cathepsin L-like protease 0.0083 0.0899 0.3974
Onchocerca volvulus 0.0083 0.0899 0.5147
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0012 0.0054
Brugia malayi GnHR receptor homolog 0.0036 0.008 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Plasmodium vivax vivapain-1 0.0032 0.0012 0.0054
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0012 0.0017
Trypanosoma cruzi cruzipain precursor, putative 0.0083 0.0899 0.1234
Schistosoma mansoni alpha-glucosidase 0.0141 0.191 0.2622
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0083 0.0899 0.1234
Onchocerca volvulus 0.0036 0.008 0.0456
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0231 0.3485 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0036 0.008 0.008
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0899 0.3974
Echinococcus granulosus cysteine protease 0.0032 0.0012 0.0012
Giardia lamblia Cathepsin L-like protease 0.0032 0.0012 0.0054
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0036 0.008 0.0109
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.1027 0.1411
Schistosoma mansoni amine GPCR 0.0036 0.008 0.0109
Brugia malayi Cathepsin L-like cysteine proteinase 0.0083 0.0899 0.1234
Leishmania major proteasome beta 5 subunit, putative 0.016 0.2249 0.9948
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Loa Loa (eye worm) hypothetical protein 0.0097 0.1145 0.1572
Echinococcus multilocularis netrin receptor unc 5 0.0062 0.0529 0.0529
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.016 0.2249 1
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0124 0.1625 0.2231
Mycobacterium ulcerans beta-lactamase 0.0036 0.0081 0.0362
Echinococcus granulosus biogenic amine 5HT receptor 0.0036 0.008 0.008
Echinococcus multilocularis cathepsin b 0.0448 0.7284 0.7284
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0036 0.008 0.008
Echinococcus multilocularis caspase 2 0.006 0.0498 0.0498
Giardia lamblia Cathepsin B precursor 0.0161 0.2261 1
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0124 0.1625 0.7186
Brugia malayi Papain family cysteine protease containing protein 0.0083 0.0899 0.1234
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0036 0.008 0.008
Echinococcus multilocularis cathepsin b 0.0448 0.7284 0.7284
Trypanosoma brucei proteasome beta 6 subunit 0.0124 0.1625 0.7186
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0012 0.0054
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Mycobacterium ulcerans proteasome PrcB 0.016 0.2249 1
Echinococcus granulosus neuropeptide receptor 0.0036 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0032 0.0012 0.0054
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0131 0.1746 0.2397
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0081 0.0112
Echinococcus granulosus peptide allatostatin:somatostatin 0.0036 0.008 0.008
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0012 0.0017
Toxoplasma gondii cathepsin CPL 0.0083 0.0899 0.3974
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0034 0.0047 0.0047
Echinococcus multilocularis neuropeptides capa receptor 0.0036 0.008 0.008
Echinococcus multilocularis neuropeptides capa receptor 0.0036 0.008 0.008
Onchocerca volvulus Cathepsin L homolog 0.0032 0.0012 0.007
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0077 0.0798 0.3527
Entamoeba histolytica aminopeptidase, putative 0.0034 0.0047 0.0209
Loa Loa (eye worm) inositol-1 0.0037 0.0098 0.0134
Giardia lamblia Cathepsin B precursor 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Brugia malayi hypothetical protein 0.0036 0.008 0.0109
Leishmania major cathepsin L-like protease 0.0083 0.0899 0.3974
Loa Loa (eye worm) hypothetical protein 0.0131 0.1746 0.2397
Schistosoma mansoni amine GPCR 0.0036 0.008 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.008 0.0109
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0081 0.036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Trypanosoma cruzi cysteine proteinase, putative 0.0032 0.0012 0.0017
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0032 0.0012 0.0054
Echinococcus multilocularis inhibitor of apoptosis protein 0.0131 0.1746 0.1746
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0124 0.1625 0.7224
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0032 0.0012 0.0054
Brugia malayi Cathepsin L-like precursor 0.0083 0.0899 0.1234
Echinococcus multilocularis somatostatin receptor 0.0036 0.008 0.008
Echinococcus granulosus cathepsin L cysteine proteinase 0.0083 0.0899 0.0899
Brugia malayi Cathepsin L-like precursor 0.0083 0.0899 0.1234
Mycobacterium tuberculosis Probable oxidoreductase 0.0217 0.3236 0.9285
Entamoeba histolytica hypothetical protein 0.0035 0.0069 0.0306
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0098 0.0433
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0083 0.0899 0.1234
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Loa Loa (eye worm) beta-lactamase 0.0036 0.0081 0.0112
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.1027 0.1027
Echinococcus multilocularis G-protein coupled receptor, putative 0.0036 0.008 0.008
Echinococcus multilocularis proteasome (prosome, macropain) 0.016 0.2249 0.2249
Schistosoma mansoni myosin xvIII 0.0036 0.008 0.0109
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0036 0.008 0.0109
Echinococcus multilocularis neuropeptide s receptor 0.0036 0.008 0.008
Onchocerca volvulus 0.0095 0.1103 0.6317
Schistosoma mansoni cathepsin F (C01 family) 0.0083 0.0899 0.1234
Brugia malayi G protein-coupled receptor 0.0036 0.008 0.0109
Schistosoma mansoni biogenic amine (5HT) receptor 0.0036 0.008 0.0109
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0069 0.0069
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0012 0.0054
Brugia malayi G-protein coupled receptor 0.0036 0.008 0.0109
Schistosoma mansoni cathepsin F (C01 family) 0.0083 0.0899 0.1234
Echinococcus granulosus serotonin receptor 0.0036 0.008 0.008
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0036 0.008 0.0109
Onchocerca volvulus 0.0083 0.0899 0.5147
Giardia lamblia Cathepsin B precursor 0.0032 0.0012 0.0054
Mycobacterium leprae proteasome (beta subunit) PrcB 0.016 0.2249 0.6952
Mycobacterium tuberculosis Probable dehydrogenase 0.0195 0.2855 0.8194
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.008 0.008
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0084 0.0115
Giardia lamblia Proteasome subunit beta type 2 0.0077 0.0798 0.3527
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0077 0.0798 0.3527
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0077 0.0798 0.1095
Echinococcus granulosus allatostatin A receptor 0.0036 0.008 0.008
Onchocerca volvulus 0.0036 0.008 0.0456
Schistosoma mansoni adenoreceptor 0.0036 0.008 0.0109
Echinococcus granulosus cathepsin b 0.0448 0.7284 0.7284
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0036 0.008 0.0109
Brugia malayi Proteasome A-type and B-type family protein 0.016 0.2249 0.3088
Schistosoma mansoni neuropeptide f receptor 76f 0.0036 0.008 0.0109
Echinococcus granulosus cathepsin L 0.0032 0.0012 0.0012
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0515 0.229
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.1027 0.1027
Brugia malayi Cathepsin L-like precursor 0.0083 0.0899 0.1234
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0098 0.0433
Brugia malayi putative neuropeptide receptor 0.0036 0.008 0.0109
Schistosoma mansoni cathepsin C 0.0032 0.0012 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0899 0.3974
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.008 0.008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0899 0.3974
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0084 0.0372
Plasmodium falciparum cysteine proteinase falcipain 3 0.0083 0.0899 0.3995
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0081 0.0112
Schistosoma mansoni opsin-like receptor 0.0036 0.008 0.0109
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0217 0.3236 0.9285
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0098 0.0433
Brugia malayi ORL1-like opioid receptor 0.0036 0.008 0.0109
Trypanosoma cruzi aminopeptidase, putative 0.0034 0.0047 0.0065
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0032 0.0012 0.0054
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0034 0.0047 0.0208
Onchocerca volvulus 0.0036 0.008 0.0456
Brugia malayi Serotonin receptor 0.0036 0.008 0.0109
Loa Loa (eye worm) hypothetical protein 0.0032 0.0012 0.0017
Plasmodium falciparum serine repeat antigen 6 0.0032 0.0012 0.0054
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0077 0.0798 0.0798
Entamoeba histolytica cysteine proteinase, putative 0.0083 0.0899 0.3995
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0032 0.0012 0.0054
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.008 0.0109
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.008 0.008
Brugia malayi Uncoordinated protein 44 0.0062 0.0529 0.0726
Schistosoma mansoni biogenic amine receptor 0.0036 0.008 0.0109
Giardia lamblia Cathepsin B precursor 0.0032 0.0012 0.0054
Echinococcus multilocularis orexin receptor type 2 0.0036 0.008 0.008
Schistosoma mansoni neuropeptide F-like receptor 0.0036 0.008 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Onchocerca volvulus 0.006 0.0498 0.2855
Brugia malayi hypothetical protein 0.0036 0.008 0.0109
Onchocerca volvulus 0.0036 0.008 0.0456
Plasmodium vivax proteasome subunit beta type-2, putative 0.0077 0.0798 0.3546
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0036 0.008 0.0109
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0084 0.0372
Plasmodium falciparum serine repeat antigen 8 0.0032 0.0012 0.0054
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0034 0.0047 0.0047
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.008 0.0109
Schistosoma mansoni opsin-like receptor 0.0036 0.008 0.0109
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0098 0.0433
Schistosoma mansoni alpha glucosidase 0.0036 0.0084 0.0115
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0036 0.008 0.0109
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0081 0.0234
Onchocerca volvulus 0.0036 0.008 0.0456
Schistosoma mansoni inositol monophosphatase 0.0037 0.0098 0.0134
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0036 0.008 0.0109
Giardia lamblia Cathepsin L precursor 0.0032 0.0012 0.0054
Echinococcus multilocularis transient receptor potential ion channel A 0.0094 0.1088 0.1088
Onchocerca volvulus 0.0036 0.008 0.0456
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.008 0.0109
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0036 0.008 0.008
Entamoeba histolytica cysteine proteinase 1, putative 0.0032 0.0012 0.0054
Brugia malayi neuropeptide F receptor 0.0036 0.008 0.0109
Echinococcus granulosus aminopeptidase N 0.0034 0.0047 0.0047
Plasmodium falciparum glutathione reductase 0.0085 0.0943 0.4192
Onchocerca volvulus 0.0083 0.0899 0.5147
Giardia lamblia Hypothetical protein 0.0032 0.0012 0.0054
Brugia malayi hypothetical protein 0.0036 0.008 0.0109
Giardia lamblia Hypothetical protein 0.0032 0.0012 0.0054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0899 0.3974
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.016 0.2249 0.3088
Brugia malayi Dopamine receptor 0.0036 0.008 0.0109
Schistosoma mansoni histamine h1 receptor 0.0036 0.008 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.008 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.008 0.008
Schistosoma mansoni transient receptor potential channel 4 0.0097 0.1145 0.1572
Brugia malayi Death domain containing protein 0.0062 0.0529 0.0726
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0083 0.0899 0.0899
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0012 0.0054
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0084 0.0372
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0084 0.0374
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0081 0.0234
Trypanosoma cruzi major cysteine proteinase, putative 0.0032 0.0012 0.0017
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.008 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Brugia malayi Cell death protein 3 precursor 0.006 0.0498 0.0684
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0034 0.0047 0.0047
Plasmodium vivax glutathione reductase, putative 0.0085 0.0943 0.4192
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0036 0.008 0.008
Plasmodium falciparum serine repeat antigen 5 0.0032 0.0012 0.0054
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.008 0.008
Schistosoma mansoni neuropeptide F-like receptor 0.0036 0.008 0.0109
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0515 0.0707
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0899 0.3974
Loa Loa (eye worm) hypothetical protein 0.0083 0.0899 0.1234
Trypanosoma cruzi cysteine peptidase, putative 0.0083 0.0899 0.1234
Echinococcus granulosus neuropeptide Y receptor 0.0036 0.008 0.008
Trypanosoma brucei Aminopeptidase M1, putative 0.0034 0.0047 0.0208
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.0081 0.0112
Onchocerca volvulus 0.0036 0.008 0.0456
Echinococcus granulosus neuropeptide FF receptor 2 0.0036 0.008 0.008
Plasmodium vivax serine-repeat antigen (SERA) 0.0032 0.0012 0.0054
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0032 0.0012 0.0054
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0069 0.0069
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0032 0.0012 0.0054
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.1027 0.1411
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0098 0.0435
Schistosoma mansoni neuropeptide receptor 0.0036 0.008 0.0109
Schistosoma mansoni transient receptor potential channel 0.0097 0.1145 0.1572
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0195 0.2855 0.8194
Trypanosoma brucei proteasome subunit beta type-5, putative 0.016 0.2249 0.9948
Giardia lamblia Cathepsin L precursor 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0032 0.0012 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0032 0.0012 0.0054
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0032 0.0012 0.0054
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0084 0.0084
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0448 0.7284 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0032 0.0012 0.0054
Trypanosoma cruzi cysteine peptidase, putative 0.0083 0.0899 0.1234
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0084 0.0372
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0195 0.2855 0.8194
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0081 0.036
Plasmodium vivax vivapain-3 0.0032 0.0012 0.0054
Giardia lamblia Cysteine protease 0.0032 0.0012 0.0054
Brugia malayi Thioredoxin reductase 0.0085 0.0943 0.1294
Brugia malayi G protein-coupled receptor F59B2.13 0.0036 0.008 0.0109
Toxoplasma gondii preprocathepsin c precursor, putative 0.0032 0.0012 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0012 0.0054
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0161 0.2261 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.008 0.0109
Loa Loa (eye worm) hypothetical protein 0.0062 0.0533 0.0732
Onchocerca volvulus Cathepsin L homolog 0.0083 0.0899 0.5147
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0077 0.0798 0.3546
Plasmodium vivax proteasome subunit beta type-1, putative 0.0124 0.1625 0.7224
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0448 0.7284 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Schistosoma mansoni hypothetical protein 0.0131 0.1746 0.2397
Schistosoma mansoni biogenic amine receptor 0.0036 0.008 0.0109
Plasmodium vivax serine-repeat antigen (SERA) 0.0032 0.0012 0.0054
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0034 0.0047 0.0065
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0081 0.0234
Onchocerca volvulus 0.0036 0.0081 0.0467
Schistosoma mansoni hypothetical protein 0.0036 0.008 0.0109
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0081 0.0252
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0036 0.008 0.008
Schistosoma mansoni growth hormone secretagogue receptor 0.0036 0.008 0.0109
Onchocerca volvulus 0.0036 0.008 0.0456
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Trypanosoma cruzi cysteine peptidase, putative 0.0032 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Schistosoma mansoni hypothetical protein 0.0062 0.0529 0.0726
Brugia malayi cathepsin L-like precursor 0.0083 0.0899 0.1234
Echinococcus multilocularis g protein coupled receptor 0.0036 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0083 0.0899 0.1234
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0084 0.0084
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0081 0.0362
Onchocerca volvulus 0.0036 0.008 0.0456
Echinococcus granulosus cathepsin L cysteine protease 0.0032 0.0012 0.0012
Echinococcus granulosus g protein coupled receptor 0.0036 0.008 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.008 0.0109
Echinococcus multilocularis cathepsin L cysteine protease 0.0083 0.0899 0.0899
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Leishmania major cathepsin L-like protease 0.0083 0.0899 0.3974
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0899 0.3974
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0899 0.3974
Brugia malayi cathepsin L precursor 0.0032 0.0012 0.0017
Onchocerca volvulus 0.0083 0.0899 0.5147
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Echinococcus multilocularis neuropeptide FF receptor 2 0.0036 0.008 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.008 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0012 0.0054
Loa Loa (eye worm) neuropeptide F receptor 0.0036 0.008 0.0109
Brugia malayi cathepsin L-like cysteine proteinase 0.0032 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Schistosoma mansoni hypothetical protein 0.006 0.0498 0.0684
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0515 0.0515
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0069 0.0094
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.016 0.2249 0.9948
Giardia lamblia Cathepsin B precursor 0.0032 0.0012 0.0054
Schistosoma mansoni transient receptor potential channel 0.0064 0.0571 0.0784
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0032 0.0012 0.0017
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0012 0.0017
Giardia lamblia Cathepsin B precursor 0.0032 0.0012 0.0054
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0036 0.008 0.0109
Plasmodium falciparum serine repeat antigen 4 0.0032 0.0012 0.0054
Echinococcus granulosus neuropeptide receptor A26 0.0036 0.008 0.008
Plasmodium vivax thioredoxin reductase, putative 0.0085 0.0943 0.4192
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0084 0.0372
Echinococcus granulosus short transient receptor potential channel 6 0.0064 0.0571 0.0571
Loa Loa (eye worm) hypothetical protein 0.0036 0.0081 0.0112
Trypanosoma cruzi cysteine proteinase, putative 0.0032 0.0012 0.0017
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0034 0.0047 0.0208
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0899 0.3974
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Echinococcus multilocularis serotonin receptor 0.0036 0.008 0.008
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0098 0.0098
Echinococcus granulosus netrin receptor unc 5 0.0062 0.0529 0.0529
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Echinococcus granulosus Ankyrin 0.0062 0.0533 0.0533
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0034 0.0047 0.0065
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0032 0.0012 0.0017
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0032 0.0012 0.0054
Giardia lamblia Encystation-specific protease 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0161 0.2261 0.3104
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.008 0.008
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0084 0.0374
Brugia malayi Transient-receptor-potential like protein 0.0036 0.008 0.011
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.008 0.008
Schistosoma mansoni amine GPCR 0.0036 0.008 0.0109
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0084 0.0372
Echinococcus multilocularis neuropeptide Y receptor 0.0036 0.008 0.008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0012 0.0017
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0036 0.008 0.008
Plasmodium vivax vivapain-2 0.0083 0.0899 0.3995
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0036 0.008 0.008
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0036 0.008 0.0109
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0081 0.036
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0084 0.0115
Toxoplasma gondii ABC1 family protein 0.0036 0.0081 0.036
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0083 0.0899 0.3995
Echinococcus multilocularis transient receptor potential gamma protein 0.0097 0.1145 0.1145
Schistosoma mansoni neuropeptide receptor 0.0036 0.008 0.0109
Brugia malayi Protein kinase domain containing protein 0.0062 0.0529 0.0726
Onchocerca volvulus 0.0034 0.0047 0.027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Brugia malayi Cathepsin L-like precursor 0.0083 0.0899 0.1234
Onchocerca volvulus 0.0083 0.0899 0.5147
Onchocerca volvulus 0.0083 0.0899 0.5147
Plasmodium falciparum cysteine proteinase falcipain 1 0.0032 0.0012 0.0054
Mycobacterium ulcerans lipase LipD 0.0036 0.0081 0.0362
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0034 0.0047 0.0047
Onchocerca volvulus Cathepsin L homolog 0.0083 0.0899 0.5147
Plasmodium falciparum serine repeat antigen 1 0.0032 0.0012 0.0054
Echinococcus multilocularis neuropeptide receptor 0.0036 0.008 0.008
Echinococcus multilocularis Ankyrin 0.0062 0.0533 0.0533
Brugia malayi hypothetical protein 0.0036 0.008 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0032 0.0012 0.0054
Echinococcus granulosus dro:myosuppressin receptor 0.0036 0.008 0.008
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.1027 0.1411
Echinococcus multilocularis g-protein coupled receptor 0.0036 0.008 0.008
Giardia lamblia Cathepsin B precursor 0.0161 0.2261 1
Brugia malayi follicle stimulating hormone receptor 0.0267 0.4114 0.5649
Brugia malayi Dopamine receptor protein 1 0.0036 0.008 0.0109
Brugia malayi AKH receptor 0.0036 0.008 0.0109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0899 0.3974
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0032 0.0012 0.0017
Echinococcus multilocularis serotonin receptor 0.0036 0.008 0.008
Schistosoma mansoni inhibitor of apoptosis protein 0.0131 0.1746 0.2397
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.008 0.008
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0098 0.0134
Onchocerca volvulus 0.0036 0.008 0.0456
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0515 0.2278
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.008 0.0109
Trypanosoma cruzi cysteine peptidase, putative 0.0083 0.0899 0.1234
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0062 0.0533 0.0732
Onchocerca volvulus 0.0036 0.008 0.0456
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0012 0.0054
Brugia malayi Serotonin receptor 0.0036 0.008 0.0109
Plasmodium falciparum serine repeat antigen 9 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0032 0.0012 0.0017
Echinococcus granulosus death domain containing protein 0.0062 0.0529 0.0529
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0161 0.2261 0.3104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0032 0.0012 0.0054
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.016 0.2249 0.6455
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0081 0.0234
Echinococcus granulosus transient receptor potential ion channel A 0.0094 0.1088 0.1088
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0034 0.0047 0.0047
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0131 0.1746 0.1746
Onchocerca volvulus 0.0032 0.0012 0.007
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.1027 0.1411
Onchocerca volvulus 0.0131 0.1746 1
Brugia malayi hypothetical protein 0.0034 0.0047 0.0065
Entamoeba histolytica hypothetical protein 0.0035 0.0069 0.0306
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0217 0.3236 0.9285
Schistosoma mansoni biogenic amine receptor 0.0036 0.008 0.0109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0899 0.3974
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0036 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0083 0.0899 0.3974
Brugia malayi Peptidase family M1 containing protein 0.0034 0.0047 0.0065
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0032 0.0012 0.0017
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.003 0.0086
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0036 0.008 0.0109
Onchocerca volvulus Neuropeptide F receptor homolog 0.0036 0.008 0.0456
Echinococcus granulosus sex peptide receptor 0.0036 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0032 0.0012 0.0054
Echinococcus granulosus lysosomal alpha glucosidase 0.0164 0.2308 0.2308
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0899 0.3974
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0032 0.0012 0.0054
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0032 0.0012 0.0017
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0084 0.0115
Echinococcus multilocularis apoptotic protease activating factor 1 0.006 0.0498 0.0498
Trichomonas vaginalis esterase, putative 0.0036 0.0081 0.036
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0448 0.7284 1
Echinococcus granulosus orexin receptor type 2 0.0036 0.008 0.008
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0604 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0034 0.0047 0.0047
Loa Loa (eye worm) neuropeptide F receptor 0.0036 0.008 0.0109
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0034 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Brugia malayi putative neuropeptide receptor NPR1 0.0036 0.008 0.0109
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.008 0.008
Leishmania major proteasome beta 2 subunit, putative 0.0077 0.0798 0.3527
Entamoeba histolytica cysteine proteinase, putative 0.0083 0.0899 0.3995
Brugia malayi proteasome subunit beta type 2 0.0077 0.0798 0.1095
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0036 0.008 0.008
Echinococcus granulosus 7tm_1 domain containing protein 0.0036 0.008 0.008
Mycobacterium ulcerans aminopeptidase N PepN 0.0034 0.0047 0.0209
Onchocerca volvulus Netrin receptor homolog 0.0062 0.0529 0.3029
Echinococcus multilocularis cysteine protease 0.0083 0.0899 0.0899
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0032 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Brugia malayi Tachykinin-like peptides receptor 99D 0.0036 0.008 0.0109
Loa Loa (eye worm) hypothetical protein 0.0083 0.0899 0.1234
Mycobacterium leprae Probable lipase LipE 0.0036 0.0081 0.0252
Echinococcus multilocularis short transient receptor potential channel 6 0.0064 0.0571 0.0571
Echinococcus granulosus caspase 2 0.006 0.0498 0.0498
Loa Loa (eye worm) thioredoxin reductase 0.0085 0.0943 0.1294
Echinococcus granulosus g-protein coupled receptor 0.0036 0.008 0.008
Plasmodium falciparum serine repeat antigen 3 0.0032 0.0012 0.0054
Brugia malayi Peptidase family M1 containing protein 0.0034 0.0047 0.0065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.008 0.008
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0032 0.0012 0.0054
Echinococcus multilocularis cathepsin L 0.0032 0.0012 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.008 0.0109
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0084 0.0372
Loa Loa (eye worm) proteasome subunit beta type 2 0.0077 0.0798 0.1095
Schistosoma mansoni netrin receptor unc5 0.0062 0.0529 0.0726
Echinococcus granulosus tachykinin peptides receptor 99D 0.0036 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0012 0.0054
Trypanosoma brucei cysteine peptidase C (CPC) 0.0161 0.2261 1
Echinococcus granulosus apoptotic protease activating factor 1 0.006 0.0498 0.0498
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.008 0.008
Mycobacterium tuberculosis Probable reductase 0.0195 0.2855 0.8194
Schistosoma mansoni alpha-1 adrenergic receptor 0.0036 0.008 0.0109
Loa Loa (eye worm) hypothetical protein 0.0032 0.0012 0.0017
Onchocerca volvulus Cathepsin F homolog 0.0083 0.0899 0.5147
Entamoeba histolytica cysteine protease, putative 0.0032 0.0012 0.0054
Schistosoma mansoni ankyrin 23/unc44 0.0062 0.0529 0.0726
Loa Loa (eye worm) ctsf protein 0.0083 0.0899 0.1234
Echinococcus granulosus neuropeptide Y receptor 0.0036 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.006 0.0498 0.0684
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0083 0.0899 0.0899
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0036 0.008 0.008
Onchocerca volvulus 0.0036 0.0081 0.0467
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0515 0.2278
Echinococcus granulosus thioredoxin glutathione reductase 0.0086 0.0952 0.0952
Plasmodium vivax unspecified product 0.0032 0.0012 0.0054
Echinococcus multilocularis thioredoxin glutathione reductase 0.0086 0.0952 0.0952
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0081 0.036
Leishmania major cathepsin L-like protease 0.0083 0.0899 0.3974
Loa Loa (eye worm) hypothetical protein 0.0032 0.0012 0.0017
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0077 0.0798 0.1095
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.016 0.2249 0.3088
Onchocerca volvulus 0.0036 0.008 0.0456
Brugia malayi cathepsin Z-like cysteine proteinase 0.0032 0.0012 0.0017
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0036 0.008 0.0109
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.003 0.0092
Trypanosoma cruzi 20S proteasome subunit 0.0077 0.0798 0.1095
Brugia malayi fibroinase precursor 0.0032 0.0012 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.008 0.008
Brugia malayi beta-lactamase family protein 0.0036 0.0081 0.0112
Loa Loa (eye worm) hypothetical protein 0.0032 0.0012 0.0017
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0131 0.1746 0.2397
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0036 0.008 0.0109
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0081 0.0234
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0062 0.0529 0.0726
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0077 0.0798 0.3546
Brugia malayi RE15519p 0.0036 0.008 0.0109
Brugia malayi beta-lactamase 0.0036 0.0081 0.0112
Loa Loa (eye worm) melatonin receptor type 1A 0.0036 0.008 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0124 0.1625 0.1625
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0084 0.0372
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0448 0.7284 1
Schistosoma mansoni caspase-7 (C14 family) 0.006 0.0498 0.0684
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0036 0.008 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0036 0.008 0.008
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0036 0.008 0.0109
Echinococcus granulosus neuropeptides capa receptor 0.0036 0.008 0.008
Echinococcus multilocularis fmrfamide receptor 0.0036 0.008 0.008
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0081 0.0362
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0032 0.0012 0.0054
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.2308 0.2308
Brugia malayi Cathepsin L-like precursor 0.0083 0.0899 0.1234
Mycobacterium tuberculosis Conserved protein 0.0036 0.0081 0.0234
Loa Loa (eye worm) hypothetical protein 0.0448 0.7284 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0083 0.0899 0.3974
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0012 0.0017
Entamoeba histolytica cysteine protease, putative 0.0083 0.0899 0.3995
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0032 0.0012 0.0054
Trypanosoma cruzi Aminopeptidase M1, putative 0.0034 0.0047 0.0065
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0131 0.1746 0.2397
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0084 0.0372
Schistosoma mansoni cathepsin F (C01 family) 0.0083 0.0899 0.1234
Echinococcus multilocularis sex peptide receptor 0.0036 0.008 0.008
Leishmania major hypothetical protein, conserved 0.0036 0.0081 0.036
Loa Loa (eye worm) glutathione reductase 0.0085 0.0943 0.1294
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.006 0.0498 0.0684
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0081 0.0112
Plasmodium vivax vivapain-2 0.0083 0.0899 0.3995
Loa Loa (eye worm) hypothetical protein 0.0036 0.008 0.0109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0083 0.0899 0.3974
Brugia malayi cathepsin F-like cysteine proteinase 0.0032 0.0012 0.0017
Trypanosoma cruzi cysteine peptidase, putative 0.0083 0.0899 0.1234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0083 0.0899 0.3974
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0077 0.0798 0.0798
Echinococcus granulosus alpha 1A adrenergic receptor 0.0036 0.008 0.008
Onchocerca volvulus 0.0036 0.008 0.0456
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0098 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.008 0.008
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0083 0.0899 0.3995
Brugia malayi G-protein coupled receptor 0.0036 0.008 0.0109
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0032 0.0012 0.0054
Schistosoma mansoni neuropeptide receptor 0.0036 0.008 0.0109
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0036 0.008 0.008
Echinococcus granulosus cathepsin b 0.0448 0.7284 0.7284
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0036 0.008 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0012 0.0054
Schistosoma mansoni hypothetical protein 0.0035 0.0069 0.0094

Activities

Activity type Activity value Assay description Source Reference
Kd (binding) = 5.99 Displacement of [3H]dihydroazapetine from alpha-adrenoreceptor in rat vas deferens ChEMBL. 17749

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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