Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0015 | 0.0008 | 0.0008 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0017 | 0.0017 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0248 | 0.0701 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0089 | 0.0382 | 0.0382 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0636 | 0.0756 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0079 | 0.0189 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0759 | 0.2257 |
Brugia malayi | Peptidase family M1 containing protein | 0.0089 | 0.0382 | 0.0966 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0251 | 0.119 | 0.3103 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.0087 | 0.0097 |
Plasmodium falciparum | ubiquitin-conjugating enzyme E2 N, putative | 0.0673 | 0.3302 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0128 | 0.0578 | 1 |
Echinococcus multilocularis | musashi | 0.003 | 0.0087 | 0.0087 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0079 | 0.0189 |
Brugia malayi | RNA binding protein | 0.0072 | 0.0297 | 0.0743 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0128 | 0.0578 | 0.1705 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0297 | 0.0297 |
Onchocerca volvulus | 0.0273 | 0.1299 | 1 | |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0615 | 0.3009 | 0.9107 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0089 | 0.0382 | 0.0382 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.0087 | 0.0087 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0089 | 0.0382 | 0.111 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0021 | 0.0039 | 0.0039 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0248 | 0.0641 |
Onchocerca volvulus | 0.003 | 0.0087 | 0.0542 | |
Brugia malayi | Ubiquitin conjugating enzyme protein 13 | 0.0673 | 0.3302 | 0.8686 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0016 | 0.0017 | 0.0017 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0179 | 0.083 | 0.083 |
Echinococcus multilocularis | dnaJ subfamily B | 0.1193 | 0.5901 | 0.5901 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.003 | 0.0039 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0063 | 0.0252 | 0.0714 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0089 | 0.0382 | 0.111 |
Leishmania major | cytochrome p450-like protein | 0.0021 | 0.0039 | 0.0065 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0297 | 0.0297 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0017 | 0.0002 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.119 | 0.3571 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0615 | 0.3009 | 0.7911 |
Schistosoma mansoni | cpg binding protein | 0.0084 | 0.0354 | 0.0354 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.024 | 0.1134 | 0.1354 |
Plasmodium vivax | ubiquitin-conjugating enzyme E2 N, putative | 0.0673 | 0.3302 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0017 | 0.0017 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0089 | 0.0382 | 0.1052 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0128 | 0.0578 | 0.0578 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0079 | 0.0189 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0057 | 0.0221 | 0.0619 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0615 | 0.3009 | 0.3009 |
Brugia malayi | Cytochrome P450 family protein | 0.0021 | 0.0039 | 0.0059 |
Onchocerca volvulus | 0.0036 | 0.0115 | 0.0764 | |
Brugia malayi | serine/threonine kinase 12 | 0.0615 | 0.3009 | 0.7911 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0079 | 0.0189 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0156 | 0.0156 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.003 | 0.0039 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0759 | 0.2257 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0084 | 0.0354 | 0.0418 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0079 | 0.0089 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0036 | 0.0115 | 0.0115 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0021 | 0.0039 | 0.0065 |
Loa Loa (eye worm) | RNA binding protein | 0.0072 | 0.0297 | 0.035 |
Loa Loa (eye worm) | ctsf protein | 0.0016 | 0.0017 | 0.0014 |
Loa Loa (eye worm) | AUR protein kinase | 0.0615 | 0.3009 | 0.3604 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.0087 | 0.0097 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0673 | 0.3302 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0615 | 0.3009 | 0.9107 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0019 | 0.003 | 0.0039 |
Giardia lamblia | Aurora kinase | 0.0615 | 0.3009 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0248 | 0.0641 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1571 | 0.7793 | 0.7793 |
Onchocerca volvulus | Huntingtin homolog | 0.014 | 0.0636 | 0.4826 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0036 | 0.0115 | 0.0115 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0089 | 0.0382 | 0.0382 |
Trichomonas vaginalis | set domain proteins, putative | 0.0273 | 0.1299 | 0.3901 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.1681 | 0.8339 | 0.8339 |
Echinococcus multilocularis | lamin | 0.003 | 0.0087 | 0.0087 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0111 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0382 | 0.0451 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0017 | 0.0002 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0248 | 0.0641 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.0087 | 0.0087 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0027 | 0.0071 | 0.0071 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0111 | 0.0287 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0036 | 0.0115 | 0.0115 |
Loa Loa (eye worm) | cysteine protease | 0.0016 | 0.0017 | 0.0014 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0089 | 0.0382 | 0.111 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0128 | 0.0578 | 0.0578 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0089 | 0.0382 | 0.0382 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0027 | 0.007 | 0.014 |
Echinococcus granulosus | aurora kinase A | 0.0615 | 0.3009 | 0.3009 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0089 | 0.0382 | 0.6368 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0021 | 0.0039 | 0.0065 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0615 | 0.3009 | 0.9107 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0063 | 0.0252 | 0.0714 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0017 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0115 | 0.0131 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0021 | 0.0039 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0156 | 0.0156 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0111 | 0.0111 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0017 | 0.0002 |
Loa Loa (eye worm) | AUR protein kinase | 0.0615 | 0.3009 | 0.3604 |
Brugia malayi | ubiquitin conjugating enzyme protein 13 | 0.0673 | 0.3302 | 0.8686 |
Schistosoma mansoni | cpg binding protein | 0.0089 | 0.0378 | 0.0378 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0248 | 0.0701 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0089 | 0.0382 | 0.6368 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0017 | 0.0017 |
Mycobacterium leprae | putative cytochrome p450 | 0.0021 | 0.0039 | 0.5 |
Echinococcus granulosus | geminin | 0.0363 | 0.1748 | 0.1748 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0615 | 0.3009 | 0.9107 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0022 | 0.0046 | 0.0046 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0759 | 0.2257 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0089 | 0.0382 | 0.1052 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0089 | 0.0382 | 0.0382 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0017 | 0.0017 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0022 | 0.0046 | 0.0046 |
Echinococcus granulosus | tar DNA binding protein | 0.0072 | 0.0297 | 0.0297 |
Brugia malayi | Cytochrome P450 family protein | 0.0021 | 0.0039 | 0.0059 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0156 | 0.0156 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0673 | 0.3302 | 0.3956 |
Echinococcus multilocularis | tar DNA binding protein | 0.0072 | 0.0297 | 0.0297 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0174 | 0.0803 | 0.2392 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0089 | 0.0382 | 0.0382 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0019 | 0.003 | 0.0039 |
Loa Loa (eye worm) | histone methyltransferase | 0.0027 | 0.0071 | 0.0079 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0063 | 0.0252 | 0.0252 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0174 | 0.0803 | 0.2392 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0087 | 0.0097 |
Loa Loa (eye worm) | fibroinase | 0.0016 | 0.0017 | 0.0014 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0759 | 0.2257 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0017 | 0.0002 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0615 | 0.3009 | 0.3009 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.119 | 0.3571 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0016 | 0.0013 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0128 | 0.0578 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0615 | 0.3009 | 0.9107 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0251 | 0.119 | 0.1422 |
Echinococcus granulosus | lamin | 0.003 | 0.0087 | 0.0087 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0111 | 0.0111 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.003 | 0.0039 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0021 | 0.0039 | 0.0065 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0248 | 0.0641 |
Brugia malayi | Peptidase family M1 containing protein | 0.0089 | 0.0382 | 0.0966 |
Echinococcus multilocularis | aurora kinase A | 0.0615 | 0.3009 | 0.3009 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0016 | 0.0017 | 0.0014 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0156 | 0.0156 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0021 | 0.0039 | 0.0065 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0021 | 0.0039 | 0.0065 |
Schistosoma mansoni | cpg binding protein | 0.0089 | 0.0378 | 0.0378 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0063 | 0.0252 | 0.0252 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0072 | 0.0297 | 0.0743 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0089 | 0.0382 | 0.111 |
Toxoplasma gondii | aurora kinase | 0.0615 | 0.3009 | 0.9107 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0022 | 0.0046 | 0.0046 |
Trichomonas vaginalis | AGC family protein kinase | 0.0615 | 0.3009 | 0.9107 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.003 | 0.0039 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0036 | 0.0115 | 0.0115 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0063 | 0.0252 | 0.0653 |
Schistosoma mansoni | hypothetical protein | 0.0363 | 0.1748 | 0.1748 |
Schistosoma mansoni | lamin | 0.003 | 0.0087 | 0.0087 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0089 | 0.0382 | 0.111 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0759 | 0.2257 |
Brugia malayi | Cytochrome P450 family protein | 0.0095 | 0.041 | 0.104 |
Echinococcus multilocularis | 0.0021 | 0.0039 | 0.0039 | |
Leishmania major | ubiquitin-conjugating enzyme e2, putative | 0.0673 | 0.3302 | 1 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0089 | 0.0382 | 0.111 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0036 | 0.0115 | 0.0115 |
Loa Loa (eye worm) | TAR-binding protein | 0.0072 | 0.0297 | 0.035 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0156 | 0.0156 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0089 | 0.0382 | 0.111 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0111 | 0.0287 |
Leishmania major | cytochrome p450-like protein | 0.0021 | 0.0039 | 0.0065 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.2013 | 1 | 1 |
Schistosoma mansoni | lamin | 0.003 | 0.0087 | 0.0087 |
Loa Loa (eye worm) | cytochrome P450 | 0.0021 | 0.0039 | 0.004 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.003 | 0.0039 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0089 | 0.0382 | 0.0382 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0156 | 0.0156 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0021 | 0.0039 | 0.0065 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0017 | 0.0002 |
Loa Loa (eye worm) | AUR protein kinase | 0.0615 | 0.3009 | 0.3604 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0079 | 0.0189 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0079 | 0.0189 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0615 | 0.3009 | 0.3009 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.016 | 0.0735 | 0.2186 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0089 | 0.0382 | 0.111 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0049 | 0.0181 | 0.0498 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0063 | 0.0252 | 0.0714 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0015 | 0.0008 | 0.0008 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0036 | 0.0115 | 0.0115 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0089 | 0.0382 | 0.111 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0022 | 0.0046 | 0.0046 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0063 | 0.0252 | 0.0252 |
Schistosoma mansoni | cytochrome P450 | 0.0021 | 0.0039 | 0.0039 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0063 | 0.0252 | 0.0714 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0089 | 0.0382 | 0.111 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0673 | 0.3302 | 0.3956 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.003 | 0.0039 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0759 | 0.2257 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0089 | 0.0382 | 0.0451 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0615 | 0.3009 | 0.7911 |
Schistosoma mansoni | protein kinase | 0.0615 | 0.3009 | 0.3009 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.003 | 0.0039 |
Onchocerca volvulus | 0.0089 | 0.0382 | 0.2845 | |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0089 | 0.0382 | 0.0451 |
Echinococcus multilocularis | ubiquitin conjugating enzyme E2 N | 0.0673 | 0.3302 | 0.3302 |
Trypanosoma brucei | aurora B kinase | 0.0615 | 0.3009 | 0.9102 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0028 | 0.0032 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0022 | 0.0046 | 0.0046 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0079 | 0.0125 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0063 | 0.0252 | 0.0714 |
Echinococcus multilocularis | aminopeptidase N | 0.0089 | 0.0382 | 0.0382 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0017 | 0.0017 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.0087 | 0.0087 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0017 | 0.0017 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0036 | 0.0115 | 0.0115 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.0087 | 0.0186 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.1681 | 0.8339 | 0.8339 |
Brugia malayi | hypothetical protein | 0.0089 | 0.0382 | 0.0966 |
Brugia malayi | Pre-SET motif family protein | 0.024 | 0.1134 | 0.2955 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0297 | 0.0297 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0063 | 0.0252 | 0.0295 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0156 | 0.0181 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0089 | 0.0382 | 0.111 |
Trichomonas vaginalis | AGC family protein kinase | 0.0615 | 0.3009 | 0.9107 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0021 | 0.0039 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0382 | 0.0451 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0021 | 0.0039 | 0.004 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0089 | 0.0382 | 0.0382 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0063 | 0.0252 | 0.0714 |
Brugia malayi | hypothetical protein | 0.0773 | 0.3799 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0089 | 0.0382 | 0.1052 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0615 | 0.3009 | 0.9107 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.003 | 0.0039 |
Toxoplasma gondii | aminopeptidase N protein | 0.0089 | 0.0382 | 0.111 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.119 | 0.3571 |
Echinococcus granulosus | cathepsin l1 | 0.0016 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0021 | 0.0039 | 0.004 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0615 | 0.3009 | 0.9107 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0079 | 0.0167 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.119 | 0.3571 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0089 | 0.0382 | 0.111 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0063 | 0.0252 | 0.0714 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0673 | 0.3302 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0095 | 0.041 | 0.0485 |
Echinococcus granulosus | aminopeptidase N | 0.0089 | 0.0382 | 0.0382 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0165 | 0.0759 | 0.5787 |
Brugia malayi | MAP kinase sur-1 | 0.0063 | 0.0252 | 0.0622 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0089 | 0.0382 | 0.0382 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0033 | 0.01 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0008 | 0.0003 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0089 | 0.0382 | 0.111 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0089 | 0.0382 | 0.111 |
Toxoplasma gondii | ubiquitin-conjugating enzyme subfamily protein | 0.0673 | 0.3302 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.119 | 0.3571 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0089 | 0.0382 | 0.111 |
Onchocerca volvulus | 0.0089 | 0.0382 | 0.2845 | |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0089 | 0.0382 | 0.0382 |
Entamoeba histolytica | protein kinase , putative | 0.0615 | 0.3009 | 0.9107 |
Entamoeba histolytica | protein kinase, putative | 0.0615 | 0.3009 | 0.9107 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0111 | 0.0111 |
Schistosoma mansoni | ubiquitin conjugating enzyme 13 | 0.0673 | 0.3302 | 0.3302 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0111 | 0.0251 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.003 | 0.0039 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0248 | 0.0641 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0248 | 0.0701 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0636 | 0.0756 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0089 | 0.0382 | 0.0382 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0089 | 0.0382 | 0.111 |
Loa Loa (eye worm) | aminopeptidase N | 0.0089 | 0.0382 | 0.0451 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.003 | 0.0039 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0072 | 0.0297 | 0.035 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0615 | 0.3009 | 0.9107 |
Brugia malayi | Pre-SET motif family protein | 0.0036 | 0.0115 | 0.0261 |
Trypanosoma brucei | aminopeptidase, putative | 0.0089 | 0.0382 | 0.1052 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0128 | 0.0578 | 0.0578 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0248 | 0.0641 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0248 | 0.0701 |
Brugia malayi | TAR-binding protein | 0.0072 | 0.0297 | 0.0743 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.1681 | 0.8339 | 1 |
Onchocerca volvulus | 0.0084 | 0.0354 | 0.2629 | |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0089 | 0.0382 | 0.0382 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0063 | 0.0252 | 0.0252 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.003 | 0.0039 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0156 | 0.0156 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.003 | 0.0039 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0156 | 0.037 |
Brugia malayi | cytochrome P450 | 0.0021 | 0.0039 | 0.0059 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.0759 | 0.2257 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0615 | 0.3009 | 0.9107 |
Onchocerca volvulus | 0.003 | 0.0087 | 0.0542 | |
Brugia malayi | Peptidase family M1 containing protein | 0.0089 | 0.0382 | 0.0966 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0021 | 0.0039 | 0.004 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0297 | 0.0297 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.0087 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0017 | 0.0014 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0036 | 0.0115 | 0.0298 |
Brugia malayi | hypothetical protein | 0.0089 | 0.0382 | 0.0966 |
Trichomonas vaginalis | AGC family protein kinase | 0.0615 | 0.3009 | 0.9107 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0128 | 0.0578 | 0.1705 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0027 | 0.0071 | 0.0071 |
Trypanosoma brucei | protein kinase, putative | 0.0063 | 0.0252 | 0.0653 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0111 | 0.0287 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0089 | 0.0382 | 0.111 |
Schistosoma mansoni | hypothetical protein | 0.0363 | 0.1748 | 0.1748 |
Brugia malayi | Cytochrome P450 family protein | 0.0021 | 0.0039 | 0.0059 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0089 | 0.0382 | 0.111 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0079 | 0.0189 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.003 | 0.0039 |
Plasmodium vivax | SET domain protein, putative | 0.0036 | 0.0115 | 0.0298 |
Onchocerca volvulus | 0.0089 | 0.0382 | 0.2845 | |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0016 | 0.0017 | 0.0014 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0089 | 0.0382 | 0.0382 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0089 | 0.0382 | 0.0382 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0089 | 0.0382 | 0.111 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0089 | 0.0382 | 0.0382 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0063 | 0.0252 | 0.0714 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0013 | 0.0002 | 0.0002 |
Schistosoma mansoni | hypothetical protein | 0.1193 | 0.5901 | 0.5901 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0039 | 0.0039 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0248 | 0.0701 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0111 | 0.0287 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0248 | 0.0641 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.119 | 0.3571 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0248 | 0.0701 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0063 | 0.0252 | 0.0714 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0673 | 0.3302 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0017 | 0.0002 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0089 | 0.0382 | 0.111 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.0248 | 0.0701 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0063 | 0.0252 | 0.0714 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0248 | 0.0641 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0016 | 0.0017 | 0.0017 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0673 | 0.3302 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0063 | 0.0252 | 0.0714 |
Echinococcus granulosus | ubiquitin conjugating enzyme E2 N | 0.0673 | 0.3302 | 0.3302 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0017 | 0.0017 |
Onchocerca volvulus | Huntingtin homolog | 0.014 | 0.0636 | 0.4826 |
Echinococcus multilocularis | cpg binding protein | 0.0089 | 0.0378 | 0.0378 |
Schistosoma mansoni | microtubule-associated protein tau | 0.2013 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0297 | 0.0297 |
Brugia malayi | intermediate filament protein | 0.003 | 0.0087 | 0.0186 |
Trypanosoma brucei | ubiquitin-protein ligase, putative | 0.0673 | 0.3302 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0248 | 0.0641 |
Brugia malayi | TATA binding protein associated factor | 0.0089 | 0.0382 | 0.0966 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0248 | 0.0641 |
Echinococcus granulosus | cpg binding protein | 0.0089 | 0.0378 | 0.0378 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0248 | 0.0641 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0128 | 0.0578 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0128 | 0.0578 | 0.0578 |
Brugia malayi | CXXC zinc finger family protein | 0.0084 | 0.0354 | 0.0893 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0089 | 0.0382 | 0.111 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0063 | 0.0252 | 0.0252 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0128 | 0.0578 | 1 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.1681 | 0.8339 | 0.8339 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0089 | 0.0382 | 0.0382 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.003 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0084 | 0.0094 |
Entamoeba histolytica | ubiquitin-conjugating enzyme family protein | 0.0673 | 0.3302 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.1193 | 0.5901 | 0.5901 |
Brugia malayi | hypothetical protein | 0.014 | 0.0636 | 0.1637 |
Echinococcus multilocularis | geminin | 0.0363 | 0.1748 | 0.1748 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.003 | 0.0039 |
Entamoeba histolytica | aminopeptidase, putative | 0.0089 | 0.0382 | 0.111 |
Leishmania major | protein kinase, putative | 0.0615 | 0.3009 | 0.9107 |
Leishmania major | cytochrome p450-like protein | 0.0021 | 0.0039 | 0.0065 |
Trichomonas vaginalis | helicase, putative | 0.0019 | 0.003 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.0382 | 0.0451 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ID50 (functional) | > 1 M | Compound was tested for its inhibitory activity against L1210 lymphoid leukemia cells at 10 ug/mL | ChEMBL. | 3806615 |
T/C (functional) | < 125 % | Compound was tested for mean survival time of treated mice in days / mean survival time of control mice x 100 against L1210 lymphoid leukemia cells | ChEMBL. | 3806615 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.