Detailed information for compound 203185

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 438.968 | Formula: C22H33ClN3O4-
  • H donors: 2 H acceptors: 2 LogP: 3.49 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC[C@@H]1C=CCC[C@@]2(O1)C[C@@H]1CC[C@@H]3[N+]1=C(N2)N[C@]1([C@@H]3C(=O)[O-])CCC[C@H](O1)C.[Cl-]
  • InChi: 1S/C22H33N3O4.ClH/c1-3-16-8-4-5-11-21(29-16)13-15-9-10-17-18(19(26)27)22(12-6-7-14(2)28-22)24-20(23-21)25(15)17;/h4,8,14-18H,3,5-7,9-13H2,1-2H3,(H2,23,24,26,27);1H/p-1/t14-,15+,16+,17-,18+,21+,22-;/m1./s1
  • InChiKey: KBKXJAUTHBTJLR-MBODOLFUSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0068 0.0083 0.0254
Echinococcus granulosus TGF beta signal transducer SmadC 0.0049 0.005 0.0049
Echinococcus granulosus lamin 0.0114 0.0165 0.0164
Echinococcus granulosus mothers against decapentaplegic 5 0.0049 0.005 0.0049
Echinococcus granulosus histone acetyltransferase KAT2B 0.0294 0.0488 0.0487
Schistosoma mansoni cyclin l 0.0189 0.0301 0.03
Giardia lamblia Histone acetyltransferase GCN5 0.0081 0.0107 0.0564
Schistosoma mansoni ferritin 0.0036 0.0026 0.0026
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0043 0.0233
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0055 0.0059 0.0059
Trichomonas vaginalis cyclins, putative 0.1059 0.186 0.6173
Echinococcus granulosus cyclins 0.077 0.1342 0.1341
Mycobacterium leprae conserved hypothetical protein 0.0685 0.1189 1
Brugia malayi Bromodomain containing protein 0.0046 0.0043 0.013
Loa Loa (eye worm) CYL-1 protein 0.0189 0.0301 0.0925
Echinococcus multilocularis mothers against decapentaplegic 5 0.0049 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0297 0.0494 0.152
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0017 0.0017
Trichomonas vaginalis cyclins, putative 0.0189 0.0301 0.0992
Schistosoma mansoni tar DNA-binding protein 0.0142 0.0216 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.0685 0.1189 0.6391
Entamoeba histolytica cyclin, putative 0.1059 0.186 1
Echinococcus granulosus cyclin dependent kinase 7 0.0086 0.0116 0.0116
Trichomonas vaginalis D-aminoacylase, putative 0.0685 0.1189 0.3945
Mycobacterium ulcerans beta-lactamase 0.0685 0.1189 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0027 0.008
Schistosoma mansoni apoferritin-2 0.0036 0.0026 0.0026
Echinococcus multilocularis zinc finger protein 0.0027 0.0009 0.0009
Brugia malayi MH1 domain containing protein 0.0049 0.005 0.0151
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0214 0.0345 0.0345
Loa Loa (eye worm) hypothetical protein 0.0111 0.0161 0.0494
Schistosoma mansoni tar DNA-binding protein 0.0142 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0031 0.0017 0.0052
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0189 0.0301 0.03
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0043 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0043 0.0136
Loa Loa (eye worm) hypothetical protein 0.0685 0.1189 0.3664
Echinococcus granulosus cyclin y 0.0189 0.0301 0.03
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0139 0.0428
Schistosoma mansoni smad 0.0049 0.005 0.0049
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0685 0.1189 0.1494
Plasmodium vivax protein kinase Crk2 0.0091 0.0124 0.1029
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0305 0.0509 0.0508
Giardia lamblia Hypothetical protein 0.077 0.1342 0.7212
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0008 0.0021
Schistosoma mansoni ran 0.0023 0.0002 0.0002
Loa Loa (eye worm) cyclin domain-containing protein 0.0189 0.0301 0.0925
Loa Loa (eye worm) MH2 domain-containing protein 0.0049 0.005 0.0151
Leishmania major importin beta-1 subunit, putative 0.0025 0.0007 0.0023
Trypanosoma cruzi cdc2-related kinase 3 0.0091 0.0124 0.0657
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0189 0.0301 0.2513
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0007 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0047 0.0143
Brugia malayi beta-lactamase 0.0685 0.1189 0.3664
Brugia malayi Cyclin, N-terminal domain containing protein 0.1831 0.3246 1
Entamoeba histolytica hypothetical protein 0.007 0.0087 0.0454
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0006 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0124 0.0124
Leishmania major mitotic cyclin, putative 0.0189 0.0301 0.1606
Loa Loa (eye worm) hypothetical protein 0.0089 0.0121 0.0371
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0055 0.0054
Plasmodium falciparum flap endonuclease 1 0.0026 0.0008 0.0039
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0081 0.008
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0017 0.0125
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0017 0.0092
Brugia malayi Cyclin, N-terminal domain containing protein 0.0189 0.0301 0.0925
Loa Loa (eye worm) cyclin domain-containing protein 0.0682 0.1185 0.365
Echinococcus granulosus cyclin t1 0.0189 0.0301 0.03
Echinococcus multilocularis cyclins 0.077 0.1342 0.1341
Schistosoma mansoni lamin 0.0114 0.0165 0.0164
Echinococcus granulosus cyclins 0.077 0.1342 0.1341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0022 0.0066
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0685 0.1189 0.3664
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0027 0.008
Echinococcus granulosus cyclin B 0.1059 0.186 0.1859
Brugia malayi MH2 domain containing protein 0.0724 0.126 0.3882
Trichomonas vaginalis cyclin B, putative 0.1059 0.186 0.6173
Echinococcus multilocularis Smad4 0.0049 0.005 0.0049
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0043 0.0221
Plasmodium falciparum cyclin 1 0.0189 0.0301 0.2227
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0017 0.0052
Giardia lamblia Cyclin fold protein 1, putative 0.0189 0.0301 0.1606
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.1059 0.186 1
Echinococcus granulosus G1:S specific cyclin D1 0.0486 0.0833 0.0833
Schistosoma mansoni smad1 5 8 and 0.0049 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0189 0.0301 0.0925
Echinococcus multilocularis tumor protein p63 0.0357 0.0602 0.0601
Loa Loa (eye worm) glutaminase 0.0271 0.0446 0.1373
Mycobacterium ulcerans esterase/lipase LipP 0.0685 0.1189 1
Trypanosoma cruzi cdc2-related kinase 1 0.0091 0.0124 0.0657
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0091 0.0124 0.0382
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0008 0.0017
Entamoeba histolytica cyclin, domain containing protein 0.0189 0.0301 0.1606
Echinococcus granulosus cyclins 0.077 0.1342 0.1341
Brugia malayi PHD-finger family protein 0.0032 0.0019 0.0056
Trichomonas vaginalis glutaminase, putative 0.0271 0.0446 0.1475
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0025 0.0025
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0002 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0231 0.0376 0.0375
Schistosoma mansoni hypothetical protein 0.0184 0.0291 0.029
Trichomonas vaginalis cyclins, putative 0.1059 0.186 0.6173
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0091 0.0125 0.0407
Schistosoma mansoni hypothetical protein 0.0031 0.0017 0.0017
Echinococcus multilocularis ferritin 0.0036 0.0026 0.0026
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0685 0.1189 0.3664
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0189 0.0301 0.03
Trypanosoma cruzi cyclin, putative 0.1059 0.186 1
Trichomonas vaginalis conserved hypothetical protein 0.0189 0.0301 0.0992
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0025 0.0025
Brugia malayi Cyclin, N-terminal domain containing protein 0.1059 0.186 0.5729
Brugia malayi Cyclin, N-terminal domain containing protein 0.0189 0.0301 0.0925
Schistosoma mansoni cyclin d 0.0486 0.0833 0.0833
Loa Loa (eye worm) hypothetical protein 0.1059 0.186 0.5729
Echinococcus multilocularis tar DNA binding protein 0.0142 0.0216 0.0216
Mycobacterium tuberculosis Conserved protein 0.0685 0.1189 0.1494
Echinococcus granulosus cyclin y 0.0189 0.0301 0.03
Trichomonas vaginalis cyclins, putative 0.1059 0.186 0.6173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0022 0.0066
Trichomonas vaginalis bromodomain-containing protein, putative 0.0091 0.0125 0.0407
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0043 0.0221
Loa Loa (eye worm) cyclin domain-containing protein 0.0189 0.0301 0.0925
Brugia malayi Cyclin, N-terminal domain containing protein 0.0334 0.056 0.1725
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.0124 0.0406
Schistosoma mansoni cyclin B3 0.1831 0.3246 0.3245
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0007 0.0014
Giardia lamblia G2/mitotic-specific cyclin B 0.1059 0.186 1
Echinococcus granulosus Smad4 0.0049 0.005 0.0049
Brugia malayi Serotonin receptor 0.0471 0.0805 0.2479
Trichomonas vaginalis conserved hypothetical protein 0.077 0.1342 0.4452
Echinococcus granulosus cyclin k 0.0189 0.0301 0.03
Entamoeba histolytica hypothetical protein 0.0025 0.0007 0.0023
Mycobacterium ulcerans glutaminase 0.0271 0.0446 0.361
Loa Loa (eye worm) beta-lactamase 0.0685 0.1189 0.3664
Plasmodium vivax hypothetical protein, conserved 0.0189 0.0301 0.2513
Mycobacterium leprae Probable lipase LipE 0.0685 0.1189 1
Loa Loa (eye worm) hypothetical protein 0.0231 0.0376 0.1156
Echinococcus granulosus cyclins 0.077 0.1342 0.1341
Schistosoma mansoni ferritin 0.0036 0.0026 0.0026
Entamoeba histolytica cyclin, putative 0.077 0.1342 0.7212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.001 0.0025
Echinococcus granulosus cyclin G2 0.0189 0.0301 0.03
Mycobacterium tuberculosis Probable hydrolase 0.0685 0.1189 0.1494
Trichomonas vaginalis cyclins, putative 0.1059 0.186 0.6173
Loa Loa (eye worm) hypothetical protein 0.0114 0.0165 0.0506
Onchocerca volvulus 0.1701 0.3011 1
Echinococcus granulosus ferritin 0.0036 0.0026 0.0026
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0007 0.0014
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0043 0.0043
Brugia malayi Pre-SET motif family protein 0.1494 0.2641 0.8137
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0685 0.1189 0.1189
Plasmodium vivax hypothetical protein, conserved 0.0685 0.1189 1
Echinococcus multilocularis cyclin A3 4 0.0189 0.0301 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0006 0.0011
Giardia lamblia Cyclin A 0.077 0.1342 0.7212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0022 0.0066
Brugia malayi MH2 domain containing protein 0.0049 0.005 0.0151
Echinococcus granulosus snurportin 1 0.0334 0.056 0.0559
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0008 0.0028
Echinococcus granulosus beta LACTamase domain containing family member 0.0685 0.1189 0.1189
Loa Loa (eye worm) transcription factor SMAD2 0.0724 0.126 0.3882
Echinococcus multilocularis Cyclin L1 0.0189 0.0301 0.03
Giardia lamblia Kinase, CMGC CDK 0.0091 0.0124 0.0657
Echinococcus multilocularis lamin 0.0114 0.0165 0.0164
Onchocerca volvulus Cyclin L homolog 0.0189 0.0301 0.0997
Loa Loa (eye worm) hypothetical protein 0.0685 0.1189 0.3664
Loa Loa (eye worm) hypothetical protein 0.0685 0.1189 0.3664
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0264 0.0435 0.0434
Entamoeba histolytica hypothetical protein 0.0305 0.0509 0.2727
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0139 0.0428
Leishmania major cyclin 0.1059 0.186 1
Trichomonas vaginalis cyclin B, putative 0.0189 0.0301 0.0992
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0189 0.0301 0.2513
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0027 0.008
Trichomonas vaginalis cyclin B3, putative 0.0189 0.0301 0.0992
Entamoeba histolytica cell division protein kinase 2, putative 0.0091 0.0124 0.0657
Trichomonas vaginalis cyclin B3, putative 0.077 0.1342 0.4452
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0017 0.0052
Mycobacterium tuberculosis Conserved protein 0.0685 0.1189 0.1494
Schistosoma mansoni ferritin light chain 0.0036 0.0026 0.0026
Schistosoma mansoni apoferritin-2 0.0036 0.0026 0.0026
Echinococcus multilocularis cyclin G2 0.0189 0.0301 0.03
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0685 0.1189 0.1494
Plasmodium falciparum protein kinase 5 0.0091 0.0124 0.0911
Trichomonas vaginalis cyclins, putative 0.077 0.1342 0.4452
Entamoeba histolytica hypothetical protein 0.0305 0.0509 0.2727
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0005 0.001
Plasmodium vivax SET domain protein, putative 0.0214 0.0345 0.289
Schistosoma mansoni flap endonuclease-1 0.0023 0.0003 0.0002
Brugia malayi cyclin fold protein 1 variant b 0.0189 0.0301 0.0925
Leishmania major mitotic cyclin, putative 0.0189 0.0301 0.1606
Loa Loa (eye worm) bromodomain containing protein 0.0025 0.0006 0.0016
Trypanosoma cruzi cyclin 6, putative 0.1059 0.186 1
Echinococcus granulosus cyclin B3 1 0.077 0.1342 0.1341
Trichomonas vaginalis set domain proteins, putative 0.1701 0.3011 1
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0008 0.0028
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0053 0.0056 0.0169
Trypanosoma brucei cyclin 9 0.0189 0.0301 0.1617
Echinococcus multilocularis cyclin dependent kinase 0.0091 0.0124 0.0124
Loa Loa (eye worm) cyclin domain-containing protein 0.0334 0.056 0.1725
Leishmania major hypothetical protein, conserved 0.0685 0.1189 0.6391
Echinococcus granulosus tar DNA binding protein 0.0142 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.007 0.0087 0.0267
Trypanosoma brucei cdc2-related kinase 1 0.0091 0.0124 0.0669
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.001 0.0026
Echinococcus granulosus histone lysine methyltransferase setb 0.0231 0.0376 0.0375
Echinococcus granulosus GPCR family 2 0.0031 0.0017 0.0017
Giardia lamblia Hypothetical protein 0.0189 0.0301 0.1606
Loa Loa (eye worm) Smad1 0.0049 0.005 0.0151
Onchocerca volvulus 0.0685 0.1189 0.3949
Trichomonas vaginalis cyclin D, putative 0.077 0.1342 0.4452
Brugia malayi Flap endonuclease-1 0.0026 0.0008 0.0021
Echinococcus granulosus cyclin A3 4 0.0189 0.0301 0.03
Schistosoma mansoni ran 0.0023 0.0002 0.0002
Schistosoma mansoni lamin 0.0114 0.0165 0.0164
Echinococcus granulosus flap endonuclease 1 0.0026 0.0008 0.0007
Echinococcus granulosus cyclins 0.077 0.1342 0.1341
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0017 0.0017
Trichomonas vaginalis cyclin B, putative 0.077 0.1342 0.4452
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0189 0.0301 0.1617
Plasmodium falciparum histone acetyltransferase GCN5 0.0081 0.0107 0.0783
Mycobacterium tuberculosis Probable lipase LipD 0.0685 0.1189 0.1494
Trypanosoma brucei mitotic cyclin 0.0189 0.0301 0.1617
Loa Loa (eye worm) hypothetical protein 0.0685 0.1189 0.3664
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0031 0.0096
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0114 0.0165 0.0506
Brugia malayi Cyclin, N-terminal domain containing protein 0.0682 0.1185 0.365
Schistosoma mansoni bromodomain containing protein 0.007 0.0087 0.0087
Brugia malayi Cyclin, N-terminal domain containing protein 0.0189 0.0301 0.0925
Schistosoma mansoni hypothetical protein 0.0031 0.0017 0.0017
Entamoeba histolytica cyclin C, putative 0.0189 0.0301 0.1606
Trichomonas vaginalis cyclin A, putative 0.1059 0.186 0.6173
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0139 0.0428
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0002 0.0005
Leishmania major cyclin 9, putative 0.0189 0.0301 0.1606
Entamoeba histolytica cyclin family protein 0.077 0.1342 0.7212
Echinococcus multilocularis cyclins 0.077 0.1342 0.1341
Trichomonas vaginalis cyclin B, putative 0.0189 0.0301 0.0992
Loa Loa (eye worm) hypothetical protein 0.0685 0.1189 0.3664
Trichomonas vaginalis cyclin A, putative 0.0189 0.0301 0.0992
Loa Loa (eye worm) TAR-binding protein 0.0142 0.0216 0.0665
Toxoplasma gondii ABC1 family protein 0.0685 0.1189 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0305 0.0509 0.0508
Trichomonas vaginalis conserved hypothetical protein 0.0189 0.0301 0.0992
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0043 0.0221
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0016 0.0046
Echinococcus multilocularis cyclin dependent kinase 1 0.0091 0.0124 0.0124
Giardia lamblia Cyclin B-like protein 0.0189 0.0301 0.1606
Mycobacterium ulcerans hypothetical protein 0.0685 0.1189 1
Echinococcus granulosus cyclin b3 0.077 0.1342 0.1341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0027 0.008
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0002 0.0002
Echinococcus multilocularis smad 0.0049 0.005 0.0049
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0685 0.1189 0.1189
Trichomonas vaginalis D-aminoacylase, putative 0.0685 0.1189 0.3945
Brugia malayi MH2 domain containing protein 0.0049 0.005 0.0151
Plasmodium vivax importin-beta 2, putative 0.0031 0.0017 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0189 0.0301 0.0992
Echinococcus granulosus tumor protein p63 0.0357 0.0602 0.0601
Loa Loa (eye worm) acetyltransferase 0.0305 0.0507 0.1562
Brugia malayi TAR-binding protein 0.0142 0.0216 0.0665
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0043 0.0136
Brugia malayi RNA recognition motif domain containing protein 0.0142 0.0216 0.0665
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0017 0.0017
Echinococcus granulosus smad 0.0049 0.005 0.0049
Schistosoma mansoni g1/s-specific cyclin C 0.0264 0.0435 0.0434
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0022 0.0168
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0008 0.0028
Trypanosoma cruzi cdc2-related kinase 1 0.0091 0.0124 0.0657
Brugia malayi cell division control protein 2 homolog 0.0091 0.0124 0.0382
Trypanosoma cruzi CYC2-like cyclin, putative 0.1059 0.186 1
Echinococcus multilocularis cyclin y 0.0189 0.0301 0.03
Echinococcus granulosus expressed protein 0.0036 0.0026 0.0026
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1494 0.2641 0.8137
Brugia malayi beta-lactamase family protein 0.0685 0.1189 0.3664
Trypanosoma cruzi mitotic cyclin, putative 0.0189 0.0301 0.1606
Schistosoma mansoni hypothetical protein 0.0184 0.0291 0.029
Loa Loa (eye worm) hypothetical protein 0.0486 0.0833 0.2566
Echinococcus multilocularis cyclins 0.077 0.1342 0.1341
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0685 0.1189 0.1494
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0043 0.0136
Trichomonas vaginalis cyclin H, putative 0.007 0.0087 0.028
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0091 0.0125 0.1031
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0083 0.0254
Plasmodium falciparum cyclin 0.077 0.1342 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0049 0.005 0.0049
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0305 0.0507 0.0507
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.005 0.005 0.0154
Schistosoma mansoni zinc finger protein 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0053 0.0056 0.0169
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0043 0.0221
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0002 0.0002
Entamoeba histolytica cyclin, domain containing protein 0.0189 0.0301 0.1606
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0027 0.0143
Trichomonas vaginalis cyclins, putative 0.0189 0.0301 0.0992
Schistosoma mansoni hypothetical protein 0.0189 0.0301 0.03
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0214 0.0345 0.0345
Loa Loa (eye worm) hypothetical protein 0.0289 0.0479 0.1474
Giardia lamblia Kinase, CMGC CDK 0.0091 0.0124 0.0657
Brugia malayi Cyclin C 0.0264 0.0435 0.1338
Schistosoma mansoni transcription factor LCR-F1 0.0305 0.0509 0.0508
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0334 0.056 0.1724
Toxoplasma gondii hypothetical protein 0.0189 0.0301 0.2513
Brugia malayi Importin beta-1 subunit 0.0031 0.0017 0.0051
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0017 0.0017
Echinococcus multilocularis cyclin dependent kinase 1 0.0091 0.0124 0.0124
Echinococcus multilocularis GPCR, family 2 0.0031 0.0017 0.0017
Echinococcus multilocularis cyclin t1 0.0189 0.0301 0.03
Echinococcus multilocularis cyclins 0.077 0.1342 0.1341
Loa Loa (eye worm) RNA binding protein 0.0142 0.0216 0.0665
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0043 0.0132
Brugia malayi Intermediate filament tail domain containing protein 0.0114 0.0165 0.0506
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0017 0.0092
Onchocerca volvulus 0.0685 0.1189 0.3949
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0043 0.0221
Echinococcus granulosus Cyclin L1 0.0189 0.0301 0.03
Onchocerca volvulus 0.0189 0.0301 0.0997
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0022 0.0066
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0061 0.007 0.0214
Loa Loa (eye worm) cyclin domain-containing protein 0.0189 0.0301 0.0925
Schistosoma mansoni cyclin k 0.0189 0.0301 0.03
Echinococcus multilocularis cyclin dependent kinase 5 0.0091 0.0124 0.0124
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0007 0.0014
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0008 0.0044
Trypanosoma brucei mitotic cyclin 6 0.1059 0.186 1
Schistosoma mansoni ferritin light chain 0.0036 0.0026 0.0026
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0027 0.0131
Loa Loa (eye worm) glutaminase 2 0.0271 0.0446 0.1373
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0124 0.0124
Echinococcus granulosus cyclin dependent kinase 0.0091 0.0124 0.0124
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0001 0.0001
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0043 0.0043
Brugia malayi RNA, U transporter 1 0.0089 0.0121 0.037
Echinococcus granulosus cyclin 0.0264 0.0435 0.0434
Echinococcus granulosus cyclin G2 0.0189 0.0301 0.03
Giardia lamblia Hypothetical protein 0.0189 0.0301 0.1606
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.0124 0.0406
Trichomonas vaginalis cyclin B, putative 0.1059 0.186 0.6173
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0214 0.0345 0.289
Trypanosoma cruzi mitotic cyclin, putative 0.0189 0.0301 0.1606
Brugia malayi cyclin-dependent kinase 7 homolog 0.0086 0.0116 0.0356
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0091 0.0125 0.1031
Echinococcus granulosus cyclins 0.0189 0.0301 0.03
Schistosoma mansoni hypothetical protein 0.0031 0.0017 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.0124 0.0406
Trypanosoma cruzi cyclin 9, putative 0.0189 0.0301 0.1606
Echinococcus multilocularis cyclin dependent kinase 7 0.0086 0.0116 0.0116
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0142 0.0216 0.0665
Brugia malayi MH1 domain containing protein 0.0049 0.005 0.0151
Schistosoma mansoni hypothetical protein 0.0068 0.0083 0.0082
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0091 0.0124 0.0382
Echinococcus granulosus zinc finger protein 0.0027 0.0009 0.0009
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0017 0.0052
Brugia malayi MH1 domain containing protein 0.0027 0.001 0.0029
Schistosoma mansoni importin beta-1 0.0031 0.0017 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0027 0.008
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0036 0.0026 0.5
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0091 0.0124 0.0382
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0091 0.0124 0.0657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0022 0.0066
Mycobacterium tuberculosis Conserved protein 0.0685 0.1189 0.1494
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0081 0.008
Schistosoma mansoni glutaminase 0.0271 0.0446 0.0446
Toxoplasma gondii hypothetical protein 0.058 0.1002 0.8423
Mycobacterium ulcerans lipase LipD 0.0685 0.1189 1
Brugia malayi RNA binding protein 0.0142 0.0216 0.0665
Entamoeba histolytica cell division protein kinase 2, putative 0.0091 0.0124 0.0657
Brugia malayi MH1 domain containing protein 0.0027 0.001 0.0029
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0001 0.0001
Entamoeba histolytica cyclin family protein 0.077 0.1342 0.7212
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0008 0.0028
Entamoeba histolytica hypothetical protein 0.0189 0.0301 0.1606
Schistosoma mansoni hypothetical protein 0.0031 0.0017 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0116 0.0116
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0264 0.0435 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.001 0.0026
Trichomonas vaginalis D-aminoacylase, putative 0.0685 0.1189 0.3945
Loa Loa (eye worm) intermediate filament protein 0.0114 0.0165 0.0506
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.001 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0022 0.0066
Toxoplasma gondii cyclin 4, putative 0.0189 0.0301 0.2513
Trichomonas vaginalis cyclin B3, putative 0.0189 0.0301 0.0992
Entamoeba histolytica hypothetical protein 0.0305 0.0509 0.2727
Schistosoma mansoni tar DNA-binding protein 0.0142 0.0216 0.0216
Schistosoma mansoni ferritin 0.0036 0.0026 0.0026
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0086 0.0116 0.0356
Echinococcus multilocularis cyclin b3 0.077 0.1342 0.1341
Brugia malayi beta-lactamase family protein 0.0685 0.1189 0.3664
Trypanosoma cruzi cyclin, putative 0.1059 0.186 1
Echinococcus granulosus lamin dm0 0.0114 0.0165 0.0164
Schistosoma mansoni smad1 5 8 and 0.0049 0.005 0.0049
Trypanosoma brucei hypothetical protein, conserved 0.0685 0.1189 0.6396
Treponema pallidum bacterioferrin (TpF1) 0.0036 0.0026 0.5
Mycobacterium tuberculosis Possible penicillin-binding protein 0.4376 0.7809 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.003 0.0089
Brugia malayi glutaminase DH11.1 0.0271 0.0446 0.1373
Loa Loa (eye worm) nuclear factor I 0.0027 0.001 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0015 0.004
Echinococcus multilocularis beta LACTamase domain containing family member 0.0685 0.1189 0.1189
Onchocerca volvulus 0.0114 0.0165 0.0545
Brugia malayi Cyclin, N-terminal domain containing protein 0.0189 0.0301 0.0925
Trypanosoma cruzi cdc2-related kinase 3 0.0091 0.0124 0.0657
Onchocerca volvulus Protein CNPPD1 homolog 0.0189 0.0301 0.0997
Echinococcus granulosus importin subunit beta 1 0.0031 0.0017 0.0017
Brugia malayi Cyclin, N-terminal domain containing protein 0.1059 0.186 0.5729
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0006 0.0011
Echinococcus granulosus geminin 0.0184 0.0291 0.029
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0231 0.0376 0.0375
Echinococcus multilocularis cyclin B 0.1059 0.186 0.1859
Plasmodium falciparum importin beta, putative 0.0031 0.0017 0.0111
Echinococcus multilocularis musashi 0.0114 0.0165 0.0164
Onchocerca volvulus 0.0214 0.0345 0.1145
Schistosoma mansoni hypothetical protein 0.0189 0.0301 0.03
Trypanosoma cruzi hypothetical protein, conserved 0.0685 0.1189 0.6391
Schistosoma mansoni tar DNA-binding protein 0.0142 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0055 0.0059 0.0181
Plasmodium vivax cyclin 4, putative 0.0189 0.0301 0.2513
Echinococcus multilocularis expressed protein 0.0036 0.0026 0.0026
Echinococcus granulosus intermediate filament protein 0.0114 0.0165 0.0164
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0005 0.001
Onchocerca volvulus Cyclin L homolog 0.0189 0.0301 0.0997
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0214 0.0345 0.0345
Onchocerca volvulus 0.0052 0.0055 0.018
Trichomonas vaginalis penicillin-binding protein, putative 0.0685 0.1189 0.3945
Brugia malayi Smad1 0.0049 0.005 0.0151
Trypanosoma cruzi hypothetical protein, conserved 0.0189 0.0301 0.1606
Loa Loa (eye worm) hypothetical protein 0.0052 0.0055 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0022 0.0066
Echinococcus multilocularis cyclins 0.077 0.1342 0.1341
Trypanosoma brucei cyclin 3 0.0189 0.0301 0.1617
Loa Loa (eye worm) cyclin domain-containing protein 0.0189 0.0301 0.0925
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0055 0.0059 0.0059
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0008 0.0041
Echinococcus multilocularis cyclin B3 1 0.077 0.1342 0.1341
Entamoeba histolytica acetyltransferase, GNAT family 0.0081 0.0107 0.0564
Onchocerca volvulus 0.0114 0.0165 0.0545
Loa Loa (eye worm) cyclin domain-containing protein 0.1831 0.3246 1
Schistosoma mansoni Smad4 0.0049 0.005 0.0049
Trichomonas vaginalis esterase, putative 0.0685 0.1189 0.3945
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0091 0.0124 0.0124
Entamoeba histolytica hypothetical protein 0.0305 0.0509 0.2727
Trichomonas vaginalis cyclin B, putative 0.1059 0.186 0.6173
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0043 0.0233
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0091 0.0124 0.1029
Trichomonas vaginalis ferritin, putative 0.0036 0.0026 0.008
Schistosoma mansoni hypothetical protein 0.0334 0.056 0.0559
Echinococcus granulosus G2:mitotic specific cyclin B3 0.1831 0.3246 0.3245
Brugia malayi hypothetical protein 0.0189 0.0301 0.0925
Schistosoma mansoni intermediate filament proteins 0.0114 0.0165 0.0164
Onchocerca volvulus 0.0685 0.1189 0.3949
Echinococcus granulosus histone acetyltransferase KAT2B 0.0091 0.0125 0.0124
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0305 0.0507 0.0507
Echinococcus multilocularis cyclins 0.077 0.1342 0.1341
Loa Loa (eye worm) MH1 domain-containing protein 0.0049 0.005 0.0151
Echinococcus granulosus cyclin dependent kinase 5 0.0091 0.0124 0.0124
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0189 0.0301 0.2227
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0206 0.0331 0.0331
Toxoplasma gondii cyclin dependent kinase binding protein 0.0189 0.0301 0.2513
Trichomonas vaginalis conserved hypothetical protein 0.0189 0.0301 0.0992
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0231 0.0376 0.0375
Brugia malayi Protein kinase domain containing protein 0.0091 0.0124 0.0382
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.1831 0.3246 0.3245
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0043 0.0221
Loa Loa (eye worm) cyclin C 0.0264 0.0435 0.1338
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0091 0.0125 0.1031
Loa Loa (eye worm) hypothetical protein 0.0099 0.0139 0.0428
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0685 0.1189 0.3664
Echinococcus multilocularis cyclin 0.0264 0.0435 0.0434
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0189 0.0301 0.2513
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0189 0.0301 0.03
Echinococcus multilocularis geminin 0.0184 0.0291 0.029
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0189 0.0301 0.0925
Brugia malayi cytoplasmic intermediate filament protein 0.0061 0.007 0.0214
Giardia lamblia GTOR 0.0046 0.0043 0.0221
Echinococcus multilocularis cyclin G2 0.0189 0.0301 0.03
Brugia malayi Cyclin, N-terminal domain containing protein 0.0486 0.0833 0.2566
Echinococcus multilocularis snurportin 1 0.0334 0.056 0.0559
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.1059 0.186 0.5729
Onchocerca volvulus 0.1059 0.186 0.6175
Schistosoma mansoni ferritin 0.0036 0.0026 0.0026
Mycobacterium tuberculosis Probable lipase LipE 0.0685 0.1189 0.1494
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0017 0.0051
Schistosoma mansoni smad1 5 8 and 0.0049 0.005 0.0049
Echinococcus multilocularis G1:S specific cyclin D1 0.0486 0.0833 0.0833
Schistosoma mansoni cyclin G 0.0189 0.0301 0.03
Brugia malayi Bromodomain containing protein 0.0082 0.0108 0.0331
Brugia malayi hypothetical protein 0.0189 0.0301 0.0925
Schistosoma mansoni tar DNA-binding protein 0.0142 0.0216 0.0216
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0116 0.0116
Echinococcus multilocularis lamin dm0 0.0114 0.0165 0.0164
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0008 0.0044
Loa Loa (eye worm) MH2 domain-containing protein 0.0724 0.126 0.3882
Trichomonas vaginalis cyclin D, putative 0.0189 0.0301 0.0992
Trichomonas vaginalis cyclin D, putative 0.077 0.1342 0.4452
Schistosoma mansoni cyclin G2 0.0189 0.0301 0.03
Schistosoma mansoni cyclins 0.077 0.1342 0.1341
Mycobacterium tuberculosis Probable esterase LipL 0.0685 0.1189 0.1494
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0685 0.1189 1
Echinococcus multilocularis cyclins 0.077 0.1342 0.1341
Trichomonas vaginalis penicillin-binding protein, putative 0.0685 0.1189 0.3945
Brugia malayi acetyltransferase, GNAT family protein 0.0305 0.0507 0.1562
Trichomonas vaginalis cyclin B, putative 0.1059 0.186 0.6173
Trichomonas vaginalis cyclins, putative 0.0478 0.0819 0.2713
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0008 0.0007
Schistosoma mansoni cyclin B 0.1059 0.186 0.1859
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.001 0.0026
Echinococcus granulosus cyclin dependent kinase 1 0.0091 0.0124 0.0124
Plasmodium vivax cyclin homologue, putative 0.0189 0.0301 0.2513
Echinococcus multilocularis cyclin k 0.0189 0.0301 0.03
Echinococcus multilocularis microtubule associated protein 2 0.5597 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0005 0.001
Schistosoma mansoni microtubule-associated protein tau 0.5597 1 1
Trypanosoma brucei cdc2-related kinase 3 0.0091 0.0124 0.0669
Brugia malayi intermediate filament protein 0.0114 0.0165 0.0506
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0189 0.0301 0.2227
Brugia malayi Pre-SET motif family protein 0.0214 0.0345 0.1063
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0027 0.0131
Loa Loa (eye worm) hypothetical protein 0.0027 0.001 0.0029
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0049 0.005 0.0049
Echinococcus multilocularis cyclin y 0.0189 0.0301 0.03
Brugia malayi hypothetical protein 0.0305 0.0509 0.1566
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0091 0.0124 0.0657
Schistosoma mansoni hypothetical protein 0.0305 0.0509 0.0508
Schistosoma mansoni Cyclin fold protein 0.0189 0.0301 0.03

Activities

Activity type Activity value Assay description Source Reference
Selectivity (functional) = -100 Murine tumor cell selectivity as zone unit differential between (C38) colon adenocarcinoma and (LI120) murine cell line in disk diffusion soft agar colony formation assay at 75 ug/disk. ChEMBL. 15177450
Selectivity (functional) = 50 Human tumor selectivity as zone unit differential between (H116) colon tumor and (CEM) lymphocytic leukemia in disk diffusion soft agar colony formation assay at 75 ug/disk. ChEMBL. 15177450
Selectivity (functional) = 50 Human tumor selectivity was measured as zone unit differential between (H125) lung small cell carcinoma and (CEM) lymphocytic leukemia in disk diffusion soft agar colony formation assay at a concentration of 75 ug/disk ChEMBL. 15177450
Selectivity (functional) = 200 Murine tumor cell selectivity was measured as zone unit differential between (C38) colon adenocarcinoma and (CFU) normal bone marrow in disk diffusion soft agar colony formation assay at a concentration of 75 ug/disk ChEMBL. 15177450
Selectivity (functional) = 300 Murine tumor cell selectivity as zone unit differential between (LI120) murine cell line and (CFU) normal bone marrow in disk diffusion soft agar colony formation assay at 75 ug/disk. ChEMBL. 15177450

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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