Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | tumor protein p63 | 0.0362 | 0.4505 | 0.4505 |
Schistosoma mansoni | hypothetical protein | 0.0784 | 1 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0036 | 0.0269 | 0.0269 |
Schistosoma mansoni | lipoxygenase | 0.0152 | 0.1778 | 0.1778 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.007 | 0.071 | 0.071 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0017 | 0.0014 | 0.269 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0269 | 0.0269 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.002 | 0.0052 | 0.0454 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.007 | 0.071 | 0.071 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0017 | 0.0014 | 0.0022 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0017 | 0.0014 | 0.269 |
Schistosoma mansoni | lamin | 0.0031 | 0.0199 | 0.0199 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0269 | 0.0431 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0036 | 0.0269 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.0199 | 0.0199 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0018 | 0.0034 | 0.0034 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.0199 | 0.0199 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.002 | 0.0052 | 0.5 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0017 | 0.0014 | 0.0386 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0034 | 0.0034 |
Onchocerca volvulus | 0.0055 | 0.0511 | 0.1141 | |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0017 | 0.0011 | 0.0018 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0034 | 0.0055 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0018 | 0.0034 | 0.0034 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0017 | 0.0014 | 0.269 |
Onchocerca volvulus | 0.0031 | 0.0199 | 0.0394 | |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0017 | 0.0014 | 0.269 |
Schistosoma mansoni | intermediate filament proteins | 0.0031 | 0.0199 | 0.0199 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0034 | 0.0055 |
Brugia malayi | cytochrome P450 | 0.0017 | 0.0014 | 0.0023 |
Echinococcus granulosus | FTZ F1 alpha | 0.0018 | 0.0034 | 0.0034 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0017 | 0.0014 | 0.269 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0034 | 0.0055 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0034 | 0.0055 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0034 | 0.0055 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0017 | 0.0014 | 0.269 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0034 | 0.0055 |
Loa Loa (eye worm) | doublecortin family protein | 0.0036 | 0.0269 | 0.0431 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0055 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.002 | 0.0052 | 0.1942 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0036 | 0.0269 | 0.0269 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0104 | 0.1152 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0034 | 0.0034 |
Schistosoma mansoni | loxhd1 | 0.0036 | 0.0269 | 0.0269 |
Onchocerca volvulus | 0.0036 | 0.0269 | 0.0562 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.6238 | 1 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.0157 | 0.1845 | 0.2957 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0017 | 0.0014 | 0.269 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0017 | 0.0014 | 0.0122 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0017 | 0.0014 | 0.0014 |
Echinococcus multilocularis | 0.0017 | 0.0014 | 0.0014 | |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0017 | 0.0016 | 0.0016 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0018 | 0.0034 | 0.0055 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0495 | 0.6238 | 1 |
Schistosoma mansoni | cytochrome P450 | 0.0017 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0055 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.002 | 0.0052 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0034 | 0.0034 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0018 | 0.0034 | 0.0034 |
Echinococcus granulosus | cpg binding protein | 0.0058 | 0.0552 | 0.0552 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0262 | 0.0262 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0018 | 0.0034 | 0.0034 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0018 | 0.0034 | 0.0034 |
Schistosoma mansoni | coup transcription factor | 0.0018 | 0.0034 | 0.0034 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0018 | 0.0034 | 0.0034 |
Trypanosoma brucei | cytochrome P450, putative | 0.0044 | 0.0364 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0018 | 0.0034 | 0.0034 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0726 | 0.1163 |
Echinococcus granulosus | lamin | 0.0031 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0055 |
Echinococcus multilocularis | geminin | 0.0312 | 0.3861 | 0.3861 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0269 | 0.0431 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0017 | 0.0014 | 0.269 |
Onchocerca volvulus | 0.007 | 0.071 | 0.1616 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0029 | 0.017 | 0.0273 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0017 | 0.0014 | 0.0386 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0044 | 0.0364 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0262 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.017 | 0.017 |
Brugia malayi | Cytochrome P450 family protein | 0.0044 | 0.0364 | 0.0583 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.002 | 0.0052 | 0.0454 |
Leishmania major | cytochrome p450-like protein | 0.0017 | 0.0014 | 0.0386 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0044 | 0.0364 | 1 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0036 | 0.0269 | 0.0269 |
Onchocerca volvulus | 0.0036 | 0.0269 | 0.0562 | |
Echinococcus granulosus | RUN | 0.0036 | 0.0269 | 0.0269 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0262 | 0.042 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0342 | 0.425 | 0.1027 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0036 | 0.0269 | 0.0269 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0034 | 0.0034 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0018 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0044 | 0.0364 | 0.0583 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0199 | 0.0319 |
Brugia malayi | Cytochrome P450 family protein | 0.0033 | 0.0224 | 0.0359 |
Schistosoma mansoni | rab6-interacting | 0.0036 | 0.0269 | 0.0269 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0017 | 0.0014 | 0.269 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.141 | 0.226 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0034 | 0.0055 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0017 | 0.0014 | 0.269 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0018 | 0.0034 | 0.0055 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.002 | 0.0052 | 0.1092 |
Echinococcus multilocularis | cpg binding protein | 0.0058 | 0.0552 | 0.0552 |
Schistosoma mansoni | polycystin 1-related | 0.0036 | 0.0269 | 0.0269 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0034 | 0.0055 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.002 | 0.0052 | 0.1436 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0017 | 0.0014 | 0.0386 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.071 | 0.1138 |
Echinococcus multilocularis | musashi | 0.0031 | 0.0199 | 0.0199 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0018 | 0.0034 | 0.0034 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | cytochrome P450 | 0.0017 | 0.0014 | 0.0023 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0017 | 0.0014 | 0.269 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0034 | 0.0055 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.0072 | 0.0726 | 0.1654 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.6238 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0044 | 0.0364 | 1 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.0199 | 0.0319 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0034 | 0.0034 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0036 | 0.0269 | 0.0269 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.002 | 0.0052 | 0.1942 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0017 | 0.0014 | 0.269 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0057 | 0.0542 | 0.0542 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0034 | 0.0055 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0325 | 0.4023 | 0.9536 |
Schistosoma mansoni | cpg binding protein | 0.0058 | 0.0552 | 0.0552 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0034 | 0.0055 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0033 | 0.0224 | 0.0359 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0018 | 0.0034 | 0.0034 |
Onchocerca volvulus | 0.0053 | 0.0484 | 0.1076 | |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0017 | 0.0014 | 0.269 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0034 | 0.0055 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0262 | 0.0262 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0218 | 0.2632 | 0.2632 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.007 | 0.071 | 0.071 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.6238 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0017 | 0.0014 | 0.269 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.0199 | 0.0319 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0017 | 0.0014 | 0.0386 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0262 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0145 | 0.0232 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0034 | 0.0034 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0117 | 0.1315 | 0.1315 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0018 | 0.0034 | 0.0055 |
Echinococcus granulosus | geminin | 0.0312 | 0.3861 | 0.3861 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0018 | 0.0034 | 0.0034 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0034 | 0.0055 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0034 | 0.0055 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0018 | 0.0034 | 0.0034 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.6238 | 1 |
Onchocerca volvulus | 0.0031 | 0.0199 | 0.0394 | |
Loa Loa (eye worm) | CYP4Cod1 | 0.0044 | 0.0364 | 0.0583 |
Schistosoma mansoni | cpg binding protein | 0.0058 | 0.0552 | 0.0552 |
Leishmania major | cytochrome p450-like protein | 0.0044 | 0.0364 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0034 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0055 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0034 | 0.0034 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0017 | 0.0014 | 0.269 |
Leishmania major | cytochrome p450-like protein | 0.0017 | 0.0014 | 0.0386 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0018 | 0.0034 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0344 | 0.0551 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0017 | 0.0016 | 0.0016 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0042 | 0.0344 | 0.0551 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0262 | 0.0262 |
Echinococcus multilocularis | tumor protein p63 | 0.0362 | 0.4505 | 0.4505 |
Schistosoma mansoni | hypothetical protein | 0.0312 | 0.3861 | 0.3861 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.017 | 0.0273 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.6238 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0018 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0248 | 0.3023 | 0.4847 |
Schistosoma mansoni | lipoxygenase | 0.0218 | 0.2632 | 0.2632 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0018 | 0.0034 | 0.0055 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.002 | 0.0052 | 0.5 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0017 | 0.0014 | 0.269 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0055 | 0.0511 | 0.082 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0044 | 0.0364 | 0.0583 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.002 | 0.0052 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0055 | 0.0511 | 0.0511 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0663 | 0.1062 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0036 | 0.0269 | 0.0269 |
Brugia malayi | CXXC zinc finger family protein | 0.0055 | 0.0511 | 0.082 |
Loa Loa (eye worm) | hypothetical protein | 0.034 | 0.4217 | 0.676 |
Schistosoma mansoni | lamin | 0.0031 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.0199 | 0.0319 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0034 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0228 | 0.0366 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.002 | 0.0052 | 0.1092 |
Schistosoma mansoni | hypothetical protein | 0.0312 | 0.3861 | 0.3861 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0269 | 0.0431 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0218 | 0.2632 | 0.2632 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0055 |
Schistosoma mansoni | rab6-interacting | 0.0036 | 0.0269 | 0.0269 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0269 | 0.0431 |
Brugia malayi | ecdysteroid receptor | 0.0018 | 0.0034 | 0.0055 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.0199 | 0.0319 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0262 | 0.0262 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0262 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.6238 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0034 | 0.0055 |
Brugia malayi | Doublecortin family protein | 0.0036 | 0.0269 | 0.0431 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0017 | 0.0014 | 0.269 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0034 | 0.0055 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0034 | 0.0055 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0017 | 0.0014 | 0.0386 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.034 | 0.4217 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0055 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0017 | 0.0011 | 0.0018 |
Brugia malayi | Cytochrome P450 family protein | 0.0044 | 0.0364 | 0.0583 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0036 | 0.0269 | 1 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0495 | 0.6238 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0192 | 0.0307 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0034 | 0.0034 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0034 | 0.0034 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0017 | 0.0014 | 0.269 |
Brugia malayi | steroid hormone receptor | 0.0018 | 0.0034 | 0.0055 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0784 | 1 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0248 | 0.3023 | 0.4847 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0055 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.007 | 0.071 | 0.1138 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0034 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0484 | 0.0776 |
Trypanosoma brucei | hypothetical protein, conserved | 0.002 | 0.0052 | 0.1436 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0034 | 0.0055 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0018 | 0.0034 | 0.0034 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0042 | 0.0344 | 0.0551 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0262 | 1 |
Echinococcus multilocularis | lamin | 0.0031 | 0.0199 | 0.0199 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0018 | 0.0034 | 0.0034 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0342 | 0.425 | 0.1027 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0034 | 0.0055 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0034 | 0.0034 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0053 | 0.0484 | 0.0484 |
Loa Loa (eye worm) | histone methyltransferase | 0.0017 | 0.0016 | 0.0026 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0017 | 0.0014 | 0.269 |
Mycobacterium leprae | conserved hypothetical protein | 0.002 | 0.0052 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0042 | 0.0344 | 0.0551 |
Brugia malayi | Cytochrome P450 family protein | 0.0017 | 0.0014 | 0.0023 |
Echinococcus multilocularis | RUN | 0.0036 | 0.0269 | 0.0269 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0034 | 0.0034 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0017 | 0.0014 | 0.269 |
Brugia malayi | Phospholipase A2 family protein | 0.0072 | 0.0726 | 0.1163 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.