Detailed information for compound 252063

Basic information

Technical information
  • TDR Targets ID: 252063
  • Name: benzyl N-[[2-[2-[[3-(dimethylamino)-2,2-dimet hylpropyl]carbamoyl]phenyl]phenyl]methyl]carb amate
  • MW: 473.607 | Formula: C29H35N3O3
  • H donors: 2 H acceptors: 2 LogP: 5.06 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(NCc1ccccc1c1ccccc1C(=O)NCC(CN(C)C)(C)C)OCc1ccccc1
  • InChi: 1S/C29H35N3O3/c1-29(2,21-32(3)4)20-31-27(33)26-17-11-10-16-25(26)24-15-9-8-14-23(24)18-30-28(34)35-19-22-12-6-5-7-13-22/h5-17H,18-21H2,1-4H3,(H,30,34)(H,31,33)
  • InChiKey: ACKXHGYZLMTECL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • benzyl N-[[2-[2-[[3-(dimethylamino)-2,2-dimethyl-propyl]carbamoyl]phenyl]phenyl]methyl]carbamate
  • N-[[2-[2-[[[3-(dimethylamino)-2,2-dimethylpropyl]amino]-oxomethyl]phenyl]phenyl]methyl]carbamic acid benzyl ester
  • phenylmethyl N-[[2-[2-[[3-(dimethylamino)-2,2-dimethyl-propyl]carbamoyl]phenyl]phenyl]methyl]carbamate
  • N-[2-[2-[[3-(dimethylamino)-2,2-dimethyl-propyl]carbamoyl]phenyl]benzyl]carbamic acid benzyl ester
  • phenylmethyl N-[[2-[2-[(3-dimethylamino-2,2-dimethylpropyl)carbamoyl]phenyl]phenyl]methyl]carbamate
  • phenylmethyl N-[[2-[2-[(3-dimethylamino-2,2-dimethyl-propyl)carbamoyl]phenyl]phenyl]methyl]carbamate
  • N-[[2-[2-[[(3-dimethylamino-2,2-dimethylpropyl)amino]-oxomethyl]phenyl]phenyl]methyl]carbamic acid phenylmethyl ester
  • N-[2-[2-[(3-dimethylamino-2,2-dimethyl-propyl)carbamoyl]phenyl]benzyl]carbamic acid benzyl ester

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens potassium voltage-gated channel, shaker-related subfamily, member 5 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Potassium voltage-gated channel protein Shaker, putative Get druggable targets OG5_127659 All targets in OG5_127659
Schistosoma japonicum Potassium voltage-gated channel subfamily A member 5, putative Get druggable targets OG5_127659 All targets in OG5_127659
Schistosoma mansoni voltage-gated potassium channel Get druggable targets OG5_127659 All targets in OG5_127659
Schistosoma japonicum ko:K04876 potassium voltage-gated channel, Shaker-related subfamily A, member, putative Get druggable targets OG5_127659 All targets in OG5_127659
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit Get druggable targets OG5_127659 All targets in OG5_127659
Echinococcus multilocularis potassium voltage gated channel protein Get druggable targets OG5_127659 All targets in OG5_127659
Echinococcus multilocularis potassium voltage gated channel subfamily A Get druggable targets OG5_127659 All targets in OG5_127659
Echinococcus granulosus potassium voltage gated channel subfamily A Get druggable targets OG5_127659 All targets in OG5_127659
Schistosoma mansoni voltage-gated potassium channel Get druggable targets OG5_127659 All targets in OG5_127659
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127659 All targets in OG5_127659
Echinococcus granulosus potassium voltage gated channel protein Get druggable targets OG5_127659 All targets in OG5_127659
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis voltage gated potassium channel potassium voltage-gated channel, shaker-related subfamily, member 5 613 aa 521 aa 34.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Protein kinase domain containing protein 0.0016 0.028 0.0492
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0011 0.0151 0.0279
Trypanosoma brucei THT1 - hexose transporter, putative 0.0014 0.0223 0.5848
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0008 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0007 0.0048 0.0103
Giardia lamblia PHD finger protein 15 0.0009 0.0102 0.0288
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0018 0.0324 0.0568
Onchocerca volvulus 0.0006 0.0023 0.0064
Schistosoma mansoni amine GPCR 0.0092 0.2259 0.4784
Onchocerca volvulus 0.0006 0.0023 0.0064
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0008 0.0077 0.0077
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0011 0.0141 0.0141
Brugia malayi Furin-like cysteine rich region family protein 0.0152 0.3819 0.67
Echinococcus granulosus allatostatin A receptor 0.0018 0.0324 0.0324
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0365 1
Brugia malayi follicle stimulating hormone receptor 0.0018 0.0324 0.0568
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0324 0.0324
Entamoeba histolytica hypothetical protein 0.005 0.1159 0.2429
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0223 0.0437
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0018 0.0324 0.0686
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Brugia malayi Sugar transporter family protein 0.0006 0.0023 0.004
Loa Loa (eye worm) aminopeptidase N 0.0011 0.0151 0.0328
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0008 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Schistosoma mansoni jumonji domain containing protein 0.0024 0.0496 0.1049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0324 0.0686
Echinococcus granulosus g protein coupled receptor 0.0018 0.0324 0.0324
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0223 0.5848
Brugia malayi Ras protein let-60 0.0182 0.4603 0.8075
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0077 0.0164
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0203 0.043
Loa Loa (eye worm) hypothetical protein 0.0013 0.0186 0.0404
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Leishmania major DNA polymerase kappa, putative 0.0013 0.0197 0.2962
Onchocerca volvulus 0.0006 0.0023 0.0064
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Trypanosoma brucei glycerol uptake protein, putative 0.0008 0.0054 0.0914
Trypanosoma cruzi glycerol uptake protein, putative 0.0008 0.0054 0.0914
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0013 0.0186 0.0515
Schistosoma mansoni neuropeptide receptor 0.0018 0.0324 0.0686
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0013 0.0203 0.0357
Echinococcus multilocularis peregrin 0.0009 0.0102 0.0102
Brugia malayi Heterochromatin protein 1 0.0022 0.0443 0.0778
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.009 0.0146
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0102 0.0783
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0154 0.3873 0.8415
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0054 0.0068
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0074 0.1776 0.3762
Brugia malayi Major Facilitator Superfamily protein 0.0006 0.0023 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.3873 0.6795
Echinococcus granulosus dna polymerase kappa 0.0019 0.0365 0.0365
Schistosoma mansoni jumonji/arid domain-containing protein 0.0011 0.0154 0.0326
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0008 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Brugia malayi Sugar transporter family protein 0.0045 0.1037 0.182
Entamoeba histolytica ras-1, putative 0.0182 0.4603 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0074 0.1776 0.1776
Echinococcus multilocularis roundabout 2 0.0015 0.0246 0.0246
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0045 0.1037 0.1037
Echinococcus multilocularis somatostatin receptor 0.0018 0.0324 0.0324
Schistosoma mansoni tyrosine kinase 0.008 0.1951 0.4132
Onchocerca volvulus 0.0018 0.0324 0.0898
Trypanosoma brucei glucose transporter, putative 0.0014 0.0223 0.5848
Brugia malayi neuropeptide F receptor 0.0018 0.0324 0.0568
Onchocerca volvulus 0.0006 0.0023 0.0064
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0011 0.0151 0.0319
Brugia malayi G protein-coupled receptor 0.0018 0.0324 0.0568
Loa Loa (eye worm) hypothetical protein 0.0016 0.0274 0.0594
Echinococcus multilocularis calcium dependent protein kinase 0.0013 0.0196 0.0196
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0324 0.0324
Onchocerca volvulus 0.0011 0.0151 0.0418
Onchocerca volvulus 0.0018 0.0324 0.0898
Echinococcus multilocularis GPCR, family 2 0.0014 0.0214 0.0214
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0277 0.0587
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0324 0.0324
Brugia malayi Serotonin receptor 0.0224 0.57 1
Echinococcus granulosus solute carrier family 22 0.0006 0.0023 0.0023
Mycobacterium tuberculosis Conserved hypothetical protein 0.0011 0.0141 0.2016
Echinococcus granulosus biogenic amine 5HT receptor 0.0186 0.4722 0.4722
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0031 0.0661 0.0661
Trypanosoma brucei unspecified product 0.0008 0.0053 0.0879
Loa Loa (eye worm) hypothetical protein 0.0009 0.0103 0.0224
Schistosoma mansoni neuropeptide f receptor 76f 0.0018 0.0324 0.0686
Trypanosoma cruzi aminopeptidase, putative 0.0011 0.0151 0.3734
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0007 0.0048 0.0716
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0018 0.0324 0.0898
Toxoplasma gondii facilitative glucose transporter GT1 0.0045 0.1037 1
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0324 0.0686
Schistosoma mansoni tyrosine kinase 0.0082 0.1996 0.4227
Schistosoma mansoni hypothetical protein 0.0018 0.0324 0.0686
Onchocerca volvulus 0.0008 0.0054 0.0151
Trypanosoma brucei glucose transporter, putative 0.0014 0.0223 0.5848
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0008 0.0054 0.0118
Brugia malayi Serotonin/octopamine receptor family protein 7 0.015 0.378 0.6632
Trypanosoma brucei DNA polymerase IV, putative 0.0017 0.031 0.8377
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0008 0.0054 0.0115
Schistosoma mansoni sterol O-acyltransferase 1 0.0077 0.1876 0.3973
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0082 0.1996 0.1996
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0029 0.061 0.061
Mycobacterium ulcerans aminopeptidase N PepN 0.0011 0.0151 0.2177
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0356 0.9725
Brugia malayi Cam kinase protein 1 0.0013 0.0203 0.0357
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0274 0.0579
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0008 0.0054 0.0115
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0324 0.0686
Onchocerca volvulus 0.0018 0.0324 0.0898
Schistosoma mansoni sugar transporter 0.0006 0.0023 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0365 1
Brugia malayi ORL1-like opioid receptor 0.0018 0.0324 0.0568
Entamoeba histolytica protein kinase, putative 0.0013 0.0203 0.0327
Trichomonas vaginalis CAMK family protein kinase 0.0013 0.0203 0.0393
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0365 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0013 0.0197 0.2962
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.0324 0.0324
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0324 0.0704
Schistosoma mansoni biogenic amine (5HT) receptor 0.0186 0.4722 1
Echinococcus multilocularis serotonin receptor 0.0072 0.1747 0.1747
Schistosoma mansoni hypothetical protein 0.0016 0.0274 0.0579
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0077 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0186 0.0355
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0223 0.0437
Trypanosoma cruzi PAB1-binding protein , putative 0.0008 0.0069 0.1351
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0008 0.0077 0.0077
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0018 0.0324 0.0686
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Loa Loa (eye worm) hypothetical protein 0.0016 0.0278 0.0604
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0011 0.0151 0.0279
Brugia malayi RE15519p 0.0018 0.0324 0.0568
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Plasmodium falciparum calcium-dependent protein kinase 5 0.0013 0.0203 0.1778
Entamoeba histolytica Ras family GTPase 0.0182 0.4603 1
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.009 0.0146
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0029 0.061 0.061
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0013 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0008 0.0054 0.0054
Toxoplasma gondii LsmAD domain-containing protein 0.0008 0.0069 0.066
Trypanosoma brucei PAB1-binding protein , putative 0.0008 0.0069 0.1351
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0013 0.0203 0.1954
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Loa Loa (eye worm) hypothetical protein 0.0009 0.0103 0.0224
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Echinococcus multilocularis dna polymerase eta 0.0019 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0365 1
Leishmania major DNA polymerase eta, putative 0.0012 0.016 0.2329
Loa Loa (eye worm) hypothetical protein 0.0019 0.0356 0.0773
Loa Loa (eye worm) hypothetical protein 0.0008 0.0054 0.0118
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0008 0.0054 0.0308
Loa Loa (eye worm) hypothetical protein 0.007 0.1679 0.3648
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0365 1
Echinococcus granulosus o acyltransferase membrane bound domain 0.0008 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Toxoplasma gondii PHD-finger domain-containing protein 0.0009 0.0102 0.0981
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0045 0.1037 0.1037
Onchocerca volvulus 0.0011 0.0151 0.0418
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0013 0.0203 0.1778
Brugia malayi Melatonin receptor type 1A 0.0018 0.0324 0.0568
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0008 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0009 0.0103 0.0224
Trypanosoma cruzi glycerol uptake protein, putative 0.0008 0.0054 0.0914
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0006 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.0032 0.069 0.1397
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0008 0.0077 0.0136
Schistosoma mansoni glucose transport protein 0.0045 0.1037 0.2197
Brugia malayi neuropeptide F receptor 0.0018 0.0324 0.0568
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0324 0.0324
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0074 0.1776 0.3762
Schistosoma mansoni hypothetical protein 0.0154 0.3889 0.8235
Brugia malayi hypothetical protein 0.005 0.1159 0.2034
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0006 0.0023 0.0049
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0324 0.0324
Loa Loa (eye worm) Ras protein let-60 0.0182 0.4603 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0072 0.1747 0.3796
Onchocerca volvulus 0.0006 0.0023 0.0064
Onchocerca volvulus 0.0018 0.0324 0.0898
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Onchocerca volvulus 0.0006 0.0023 0.0064
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0043 0.0984 0.1726
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0365 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0277 0.0602
Schistosoma mansoni chromobox protein 0.0022 0.0443 0.0939
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.005 0.1159 0.1159
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0008 0.0054 0.0054
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0008 0.0054 0.0054
Entamoeba histolytica hypothetical protein 0.005 0.1159 0.2429
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0104 0.2563 0.4497
Loa Loa (eye worm) MBOAT family protein 0.0008 0.0054 0.0118
Brugia malayi Dopamine receptor protein 2 0.0018 0.0324 0.0568
Onchocerca volvulus 0.0018 0.0324 0.0898
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0043 0.0984 0.2137
Echinococcus granulosus netrin receptor unc 5 0.0019 0.0354 0.0354
Trypanosoma brucei Aminopeptidase M1, putative 0.0011 0.0151 0.3734
Echinococcus granulosus biogenic amine 5HT receptor 0.0072 0.1747 0.1747
Schistosoma mansoni hypothetical protein 0.005 0.1159 0.2455
Entamoeba histolytica Ras family GTPase 0.0182 0.4603 1
Trichomonas vaginalis ral, putative 0.0182 0.4603 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0103 0.0224
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0049 0.1138 0.1138
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0223 0.0437
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0324 0.0324
Echinococcus multilocularis neuropeptide receptor A26 0.0018 0.0324 0.0324
Mycobacterium ulcerans aldehyde dehydrogenase 0.0029 0.061 1
Onchocerca volvulus Tyrosine kinase homolog 0.0144 0.361 1
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.1037 0.2215
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0356 0.0624
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0324 0.0324
Trypanosoma brucei glucose transporter, putative 0.0014 0.0223 0.5848
Echinococcus granulosus dro:myosuppressin receptor 0.0018 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0134 0.3348 0.7274
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0324 0.0324
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0324 0.0704
Brugia malayi MBOAT family protein 0.0008 0.0054 0.0095
Brugia malayi hypothetical protein 0.0011 0.0151 0.0265
Echinococcus granulosus General substrate transporter 0.0039 0.0871 0.0871
Plasmodium falciparum calcium-dependent protein kinase 4 0.0013 0.0203 0.1778
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0365 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0045 0.1037 0.1037
Leishmania major glucose transporter/membrane transporter D2, putative 0.0014 0.0223 0.3409
Onchocerca volvulus 0.0018 0.0324 0.0898
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0324 0.0324
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0356 0.9725
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0077 0.0164
Brugia malayi major facilitator superfamily protein 0.0006 0.0023 0.004
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.0324 0.0324
Onchocerca volvulus 0.0006 0.0023 0.0064
Loa Loa (eye worm) hypothetical protein 0.0077 0.1876 0.4076
Schistosoma mansoni chromobox protein 0.0022 0.0443 0.0939
Brugia malayi hypothetical protein 0.0018 0.0324 0.0568
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0074 0.1776 0.1776
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Giardia lamblia DNA repair protein RAD52 0.0112 0.2783 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Loa Loa (eye worm) hypothetical protein 0.0014 0.0214 0.0464
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0008 0.0054 0.0118
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Schistosoma mansoni hypothetical protein 0.0018 0.0324 0.0686
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0011 0.0151 0.0319
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0031 0.0661 0.0661
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0008 0.0054 0.0308
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0223 0.0437
Schistosoma mansoni glucose transporter 0.0006 0.0023 0.0049
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0013 0.0203 0.0203
Echinococcus granulosus solute carrier family 22 0.0006 0.0023 0.0023
Brugia malayi putative neuropeptide receptor NPR1 0.0018 0.0324 0.0568
Loa Loa (eye worm) hypothetical protein 0.0009 0.0103 0.0224
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0009 0.0103 0.0218
Schistosoma mansoni hypothetical protein 0.0154 0.3889 0.8235
Brugia malayi chromobox protein homolog 3 0.0013 0.0186 0.0326
Loa Loa (eye worm) MBOAT family protein 0.0008 0.0054 0.0118
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Brugia malayi major facilitator superfamily protein 0.0006 0.0023 0.004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Loa Loa (eye worm) hypothetical protein 0.0182 0.4603 1
Echinococcus multilocularis Immunoglobulin 0.0009 0.0103 0.0103
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.016 0.1533
Schistosoma mansoni voltage-gated potassium channel 0.0104 0.2563 0.5428
Onchocerca volvulus 0.0018 0.0324 0.0898
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0008 0.0054 0.0054
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0018 0.0324 0.0686
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0365 0.0747
Loa Loa (eye worm) hypothetical protein 0.0072 0.1747 0.3796
Leishmania major glucose transporter, lmgt3 0.0014 0.0223 0.3409
Onchocerca volvulus 0.0006 0.0023 0.0064
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0389 1 1
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0011 0.0151 0.2177
Schistosoma mansoni myosin xvIII 0.0018 0.0324 0.0686
Echinococcus granulosus voltage gated potassium channel 0.0008 0.0077 0.0077
Brugia malayi hypothetical protein 0.0018 0.0324 0.0568
Loa Loa (eye worm) sugar transporter 0.0006 0.0023 0.005
Plasmodium falciparum ataxin-2 like protein, putative 0.0008 0.0069 0.0456
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Brugia malayi sulfakinin receptor protein 0.0018 0.0324 0.0568
Loa Loa (eye worm) heterochromatin protein 1 0.0022 0.0443 0.0964
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Echinococcus granulosus geminin 0.0154 0.3889 0.3889
Echinococcus granulosus GPCR family 2 0.0014 0.0214 0.0214
Brugia malayi ImpB/MucB/SamB family protein 0.0011 0.0141 0.0248
Echinococcus granulosus G protein coupled receptor 139 0.0018 0.0324 0.0324
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0045 0.1037 0.1037
Echinococcus granulosus solute carrier family 22 0.0006 0.0023 0.0023
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0324 0.0704
Trypanosoma cruzi hexose transporter 0.0014 0.0223 0.5848
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0223 0.5848
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Toxoplasma gondii PHD-finger domain-containing protein 0.0009 0.0102 0.0981
Loa Loa (eye worm) hypothetical protein 0.0104 0.2563 0.5569
Brugia malayi polk-prov protein 0.0012 0.0169 0.0297
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0018 0.0324 0.0686
Echinococcus multilocularis epidermal growth factor receptor 0.0152 0.3819 0.3819
Schistosoma mansoni hypothetical protein 0.0045 0.1037 0.2197
Echinococcus granulosus insulin receptor 0.0049 0.1138 0.1138
Entamoeba histolytica hypothetical protein 0.005 0.1159 0.2429
Onchocerca volvulus 0.0006 0.0023 0.0064
Loa Loa (eye worm) MH2 domain-containing protein 0.0038 0.0862 0.1873
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0013 0.0203 0.1954
Echinococcus granulosus Sugar transporter ERD6 protein 0.0006 0.0023 0.0023
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0011 0.0141 0.0307
Echinococcus multilocularis solute carrier family 22 0.0006 0.0023 0.0023
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0011 0.0151 0.3734
Schistosoma mansoni biogenic amine receptor 0.0018 0.0324 0.0686
Echinococcus multilocularis sterol O acyltransferase 1 0.0077 0.1876 0.1876
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0009 0.0103 0.0218
Brugia malayi G-protein coupled receptor 0.0018 0.0324 0.0568
Brugia malayi putative neuropeptide receptor 0.0018 0.0324 0.0568
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0077 0.0164
Echinococcus granulosus lysine specific demethylase 5A 0.0011 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0018 0.0324 0.0324
Brugia malayi Major Facilitator Superfamily protein 0.0006 0.0023 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Echinococcus granulosus calcium dependent protein kinase 0.0013 0.0196 0.0196
Giardia lamblia DINP protein human, muc B family 0.0013 0.0197 0.063
Echinococcus granulosus twitchin 0.0012 0.0173 0.0173
Leishmania major hypothetical protein, conserved 0.0008 0.0054 0.0533
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0013 0.0203 0.1954
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0054 0.0068
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0012 0.0183 0.0183
Schistosoma mansoni nephrin 0.0012 0.0166 0.0351
Echinococcus granulosus shaker cognate 0.0008 0.0077 0.0077
Plasmodium falciparum calcium-dependent protein kinase 2 0.0013 0.0203 0.1778
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Echinococcus multilocularis voltage gated potassium channel 0.0008 0.0077 0.0077
Onchocerca volvulus 0.0018 0.0324 0.0898
Schistosoma mansoni tyrosine kinase 0.0007 0.0045 0.0095
Trichomonas vaginalis transmembrane protein nessy, putative 0.0008 0.0054 0.0068
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.0324 0.0324
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0018 0.0324 0.0568
Brugia malayi Major Facilitator Superfamily protein 0.0006 0.0023 0.004
Brugia malayi hypothetical protein 0.0018 0.0324 0.0568
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0011 0.0151 0.0151
Loa Loa (eye worm) hhat protein 0.0008 0.0054 0.0118
Trypanosoma cruzi GUP1, putative 0.0008 0.0054 0.0914
Trichomonas vaginalis ras-dva small GTPase, putative 0.0182 0.4603 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0013 0.0203 0.1778
Loa Loa (eye worm) hypothetical protein 0.0015 0.0246 0.0534
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0104 0.2563 0.2563
Trichomonas vaginalis rap1 and, putative 0.0182 0.4603 1
Schistosoma mansoni glucose transport protein 0.0045 0.1037 0.2197
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Schistosoma mansoni hypothetical protein 0.0014 0.0214 0.0452
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0324 0.0324
Loa Loa (eye worm) hhat protein 0.0008 0.0054 0.0118
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Loa Loa (eye worm) hypothetical protein 0.001 0.0115 0.0249
Brugia malayi hypothetical protein 0.0018 0.0324 0.0568
Onchocerca volvulus 0.0018 0.0324 0.0898
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.0324 0.0324
Brugia malayi Calcitonin receptor-like protein seb-1 0.0043 0.0984 0.1726
Schistosoma mansoni glucose transport protein 0.0045 0.1037 0.2197
Loa Loa (eye worm) hypothetical protein 0.0012 0.0183 0.0398
Schistosoma mansoni hypothetical protein 0.0018 0.0324 0.0686
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0014 0.0214 0.0214
Echinococcus granulosus peregrin 0.0009 0.0102 0.0102
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0074 0.1776 0.1776
Echinococcus granulosus hypothetical protein 0.0327 0.8387 0.8387
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0099 0.2445 0.2445
Onchocerca volvulus 0.0018 0.0324 0.0898
Plasmodium falciparum phd finger protein, putative 0.0009 0.0102 0.0783
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0324 0.0324
Trypanosoma cruzi glycerol uptake protein, putative 0.0008 0.0054 0.0914
Echinococcus granulosus jumonji domain containing protein 0.0013 0.0199 0.0199
Echinococcus granulosus orexin receptor type 2 0.0018 0.0324 0.0324
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0324 0.0686
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0324 0.0324
Trichomonas vaginalis rheb, putative 0.0182 0.4603 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0365 0.0747
Brugia malayi hypothetical protein 0.0018 0.0324 0.0568
Onchocerca volvulus 0.0006 0.0023 0.0064
Toxoplasma gondii sugar transporter ST3 0.0006 0.0023 0.0214
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0008 0.0077 0.0077
Trypanosoma cruzi PAB1-binding protein , putative 0.0008 0.0069 0.1351
Schistosoma mansoni amine GPCR 0.0018 0.0324 0.0686
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0018 0.0324 0.0686
Trypanosoma brucei glucose transporter 2A 0.0014 0.0223 0.5848
Echinococcus multilocularis transfer RNA-Gly 0.0008 0.0077 0.0077
Echinococcus granulosus epidermal growth factor receptor 0.0082 0.1996 0.1996
Onchocerca volvulus Putative transporter 0.0006 0.0023 0.0064
Echinococcus granulosus chromobox protein 1 0.0022 0.0443 0.0443
Echinococcus granulosus g protein coupled receptor 0.0018 0.0324 0.0324
Toxoplasma gondii aldehyde dehydrogenase 0.0029 0.061 0.5876
Echinococcus multilocularis jumonji domain containing protein 0.0013 0.0199 0.0199
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0014 0.0214 0.0375
Echinococcus multilocularis potassium voltage gated channel protein 0.0104 0.2563 0.2563
Echinococcus multilocularis sex peptide receptor 0.0018 0.0324 0.0324
Brugia malayi Death domain containing protein 0.0016 0.0274 0.048
Echinococcus granulosus synaptic vesicle 2 protein 0.0006 0.0023 0.0023
Toxoplasma gondii transporter, major facilitator family protein 0.0006 0.0023 0.0214
Brugia malayi Peptidase family M1 containing protein 0.0011 0.0151 0.0265
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0443 0.0918
Leishmania major glycerol uptake protein, putative 0.0008 0.0054 0.0533
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0018 0.0324 0.0324
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0018 0.0324 0.0324
Schistosoma mansoni hypothetical protein 0.0009 0.0102 0.0217
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0008 0.0054 0.0115
Onchocerca volvulus 0.0018 0.0324 0.0898
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0074 0.1776 0.3117
Echinococcus granulosus 7tm_1 domain containing protein 0.0018 0.0324 0.0324
Leishmania major DNA polymerase eta, putative 0.0019 0.0356 0.5669
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0223 0.0437
Brugia malayi Sugar transporter family protein 0.0006 0.0023 0.004
Echinococcus granulosus neuropeptide FF receptor 2 0.0018 0.0324 0.0324
Schistosoma mansoni biogenic amine (5HT) receptor 0.0072 0.1747 0.3699
Toxoplasma gondii hypothetical protein 0.0008 0.0054 0.0516
Brugia malayi Fibronectin type III domain containing protein 0.0009 0.0103 0.018
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0011 0.0141 0.0141
Echinococcus granulosus death domain containing protein 0.0016 0.0274 0.0274
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.061 0.1292
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0074 0.1776 0.3762
Loa Loa (eye worm) hypothetical protein 0.0015 0.0246 0.0534
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0007 0.0048 0.0048
Trypanosoma cruzi GUP1, putative 0.0008 0.0054 0.0914
Echinococcus multilocularis geminin 0.0154 0.3889 0.3889
Echinococcus granulosus g-protein coupled receptor 0.0018 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Trypanosoma brucei unspecified product 0.0008 0.0053 0.0879
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0011 0.0151 0.2177
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0029 0.061 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Loa Loa (eye worm) latrophilin receptor protein 2 0.0014 0.0214 0.0464
Echinococcus multilocularis allatostatin A receptor 0.0018 0.0324 0.0324
Onchocerca volvulus 0.001 0.0115 0.0318
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0045 0.1037 0.1037
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0011 0.0141 0.0299
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0013 0.0203 0.0203
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0011 0.0151 0.0151
Trichomonas vaginalis dexras1, putative 0.0182 0.4603 1
Echinococcus granulosus o acyltransferase membrane bound domain 0.0008 0.0054 0.0054
Echinococcus granulosus neuropeptide receptor 0.0018 0.0324 0.0324
Echinococcus granulosus neuroglian 0.0012 0.0166 0.0166
Brugia malayi Dopamine receptor protein 1 0.0018 0.0324 0.0568
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0011 0.0151 0.0151
Brugia malayi MBOAT family protein 0.0008 0.0054 0.0095
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Onchocerca volvulus 0.014 0.3503 0.9702
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Schistosoma mansoni amine GPCR 0.0018 0.0324 0.0686
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0018 0.0324 0.0568
Brugia malayi AKH receptor 0.0018 0.0324 0.0568
Brugia malayi PHD-finger family protein 0.0009 0.0102 0.018
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.0324 0.0324
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Echinococcus multilocularis netrin receptor unc 5 0.0019 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0008 0.0069 0.015
Echinococcus granulosus chromobox protein 1 0.0022 0.0443 0.0443
Schistosoma mansoni opsin-like receptor 0.0018 0.0324 0.0686
Loa Loa (eye worm) hypothetical protein 0.0013 0.0203 0.0442
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0008 0.0054 0.0115
Brugia malayi G protein-coupled receptor F59B2.13 0.0018 0.0324 0.0568
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0018 0.0324 0.0704
Onchocerca volvulus 0.0018 0.0324 0.0898
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0011 0.0151 0.0151
Onchocerca volvulus 0.0006 0.0023 0.0064
Schistosoma mansoni hypothetical protein 0.003 0.0627 0.1328
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0324 0.0324
Onchocerca volvulus Neuropeptide F receptor homolog 0.0018 0.0324 0.0898
Echinococcus multilocularis ras gtpase 0.0182 0.4603 0.4603
Trichomonas vaginalis porcupine, putative 0.0008 0.0054 0.0068
Schistosoma mansoni jumonji/arid domain-containing protein 0.0011 0.0154 0.0326
Brugia malayi hypothetical protein 0.0006 0.0023 0.004
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0274 0.0274
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0324 0.0686
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0013 0.0203 0.1778
Loa Loa (eye worm) voltage-gated potassium channel 0.0008 0.0077 0.0168
Loa Loa (eye worm) hypothetical protein 0.0009 0.0102 0.0223
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Loa Loa (eye worm) major facilitator superfamily transporter 0.0006 0.0023 0.005
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0443 0.0918
Echinococcus granulosus roundabout 2 0.0015 0.0246 0.0246
Echinococcus multilocularis neuroglian 0.0012 0.0166 0.0166
Echinococcus multilocularis 0.0047 0.1076 0.1076
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0009 0.0102 0.0217
Schistosoma mansoni alpha-1 adrenergic receptor 0.0018 0.0324 0.0686
Trypanosoma brucei glycerol uptake protein, putative 0.0008 0.0054 0.0914
Brugia malayi G-protein coupled receptor 0.0018 0.0324 0.0568
Echinococcus granulosus defective proboscis extension response 0.0009 0.0103 0.0103
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0008 0.0054 0.0054
Brugia malayi hypothetical protein 0.0018 0.0324 0.0568
Brugia malayi hypothetical protein 0.0018 0.0324 0.0568
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0324 0.0324
Echinococcus multilocularis potassium voltage gated channel protein 0.0008 0.0077 0.0077
Echinococcus granulosus PHD finger protein rhinoceros 0.0009 0.0102 0.0102
Echinococcus multilocularis solute carrier family 22 0.0006 0.0023 0.0023
Onchocerca volvulus 0.0006 0.0023 0.0064
Schistosoma mansoni biogenic amine receptor 0.0018 0.0324 0.0686
Loa Loa (eye worm) TK/EGFR protein kinase 0.0152 0.3819 0.8297
Schistosoma mansoni zinc finger protein 0.0008 0.0054 0.0115
Toxoplasma gondii sugar transporter ST2 0.0006 0.0023 0.0214
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Entamoeba histolytica deoxycytidyl transferase, putative 0.0011 0.0141 0.0191
Schistosoma mansoni DNA polymerase eta 0.0019 0.0356 0.0753
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0274 0.0594
Echinococcus multilocularis chromobox protein 1 0.0022 0.0443 0.0443
Schistosoma mansoni cell adhesion molecule 0.0012 0.0183 0.0388
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0324 0.0324
Onchocerca volvulus Alhambra homolog 0.0009 0.0102 0.0284
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0324 0.0686
Echinococcus granulosus potassium voltage gated channel protein 0.0008 0.0077 0.0077
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.0324 0.0324
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0324 0.0686
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0008 0.0054 0.0115
Brugia malayi MH2 domain containing protein 0.0038 0.0862 0.1512
Brugia malayi diacylglycerol acyltransferase 0.0008 0.0054 0.0095
Echinococcus multilocularis solute carrier family 22 0.0006 0.0023 0.0023
Brugia malayi Protein kinase domain containing protein 0.0049 0.1138 0.1997
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0365 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0324 0.0686
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0011 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0043 0.0984 0.2137
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0324 0.0686
Echinococcus granulosus neuropeptide receptor A26 0.0018 0.0324 0.0324
Echinococcus multilocularis aminopeptidase N 0.0011 0.0151 0.0151
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0011 0.0151 0.3734
Schistosoma mansoni neuropeptide receptor 0.0018 0.0324 0.0686
Echinococcus granulosus neuropeptide s receptor 0.0018 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0008 0.0077 0.0168
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0365 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0365 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0054 0.0118
Schistosoma mansoni hypothetical protein 0.0014 0.0214 0.0452
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0008 0.0054 0.0054
Schistosoma mansoni neuropeptide receptor 0.0018 0.0324 0.0686
Echinococcus granulosus epidermal growth factor receptor 0.0152 0.3819 0.3819
Brugia malayi Bromodomain containing protein 0.0009 0.0102 0.018
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0011 0.0151 0.0151
Echinococcus granulosus fmrfamide receptor 0.0018 0.0324 0.0324
Loa Loa (eye worm) TYRA-2 protein 0.0018 0.0324 0.0704
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Brugia malayi Serotonin receptor 0.0018 0.0324 0.0568
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0008 0.0054 0.0516
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0011 0.0151 0.0151
Onchocerca volvulus Netrin receptor homolog 0.0018 0.0336 0.0931
Schistosoma mansoni sugar transporter 0.0006 0.0023 0.0049
Plasmodium falciparum calcium-dependent protein kinase 3 0.0013 0.0203 0.1778
Plasmodium falciparum ataxin-2 like protein, putative 0.0008 0.0069 0.0456
Trypanosoma brucei glucose transporter, putative 0.0014 0.0223 0.5848
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0324 0.0686
Schistosoma mansoni vesicular amine transporter 0.0018 0.0323 0.0684
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0011 0.0151 0.0151
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0324 0.0704
Echinococcus multilocularis Ankyrin 0.0016 0.0277 0.0277
Trypanosoma brucei THT1 - hexose transporter, putative 0.0014 0.0223 0.5848
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0365 1
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.0324 0.0324
Schistosoma mansoni netrin receptor unc5 0.0019 0.0354 0.0749
Loa Loa (eye worm) hypothetical protein 0.0007 0.0048 0.0103
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0018 0.0324 0.0704
Brugia malayi Dopamine receptor 0.0018 0.0324 0.0568
Echinococcus granulosus 7TM GPCR rhodopsin 0.0018 0.0324 0.0324
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0324 0.0686
Echinococcus granulosus alpha 1A adrenergic receptor 0.0018 0.0324 0.0324
Echinococcus granulosus peptide allatostatin:somatostatin 0.0018 0.0324 0.0324
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0045 0.1037 0.1037
Plasmodium falciparum hexose transporter 0.0045 0.1037 1
Brugia malayi Peptidase family M1 containing protein 0.0011 0.0151 0.0265
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.015 0.378 0.8004
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0032 0.069 0.1397
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Loa Loa (eye worm) transcription factor SMAD2 0.0038 0.0862 0.1873
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.015 0.378 0.8212
Echinococcus granulosus nuclear factor of activated T cells 5 0.0082 0.199 0.199
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0324 0.0324
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0211 0.041
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0007 0.0048 0.0101
Brugia malayi hypothetical protein 0.0009 0.0103 0.018
Brugia malayi MBOAT family protein 0.0008 0.0054 0.0095
Schistosoma mansoni hypothetical protein 0.0008 0.0054 0.0115
Echinococcus multilocularis serotonin receptor 0.0072 0.1747 0.1747
Schistosoma mansoni tyrosine kinase 0.0082 0.1996 0.4227
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0324 0.0324
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0223 0.0437
Schistosoma mansoni terminal deoxycytidyl transferase 0.0011 0.0141 0.0299
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0018 0.0324 0.0704
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0324 0.0324
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0324 0.0324
Schistosoma mansoni sugar transporter 0.0006 0.0023 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0014 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.005 0.1159 0.1159
Schistosoma mansoni neuropeptide receptor 0.0018 0.0324 0.0686
Brugia malayi hypothetical protein 0.0018 0.0324 0.0568
Loa Loa (eye worm) MBOAT family protein 0.0008 0.0054 0.0118
Trypanosoma cruzi hexose transporter, putative 0.0008 0.0057 0.0998
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0324 0.0686
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0008 0.0054 0.0516
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0018 0.0324 0.0568
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0008 0.0054 0.0115
Brugia malayi hypothetical protein 0.0006 0.0023 0.004
Onchocerca volvulus 0.0006 0.0023 0.0064
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0013 0.0203 0.0442
Loa Loa (eye worm) TK/INSR protein kinase 0.0049 0.1138 0.2473
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0365 1
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0274 0.0274
Schistosoma mansoni protein kinase 0.0013 0.0203 0.043
Echinococcus granulosus g protein coupled receptor 0.0018 0.0324 0.0324
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0018 0.0324 0.0686
Brugia malayi hypothetical protein 0.0018 0.0324 0.0568
Onchocerca volvulus 0.0018 0.0324 0.0898
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Trypanosoma brucei glucose transporter, putative 0.0014 0.0223 0.5848
Trichomonas vaginalis GTP-binding protein rit, putative 0.0182 0.4603 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0013 0.0197 0.2962
Echinococcus granulosus potassium voltage gated channel protein 0.0008 0.0077 0.0077
Brugia malayi Tachykinin-like peptides receptor 99D 0.0018 0.0324 0.0568
Trypanosoma cruzi Aminopeptidase M1, putative 0.0011 0.0151 0.3734
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0365 1
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0365 0.583
Brugia malayi Latrophilin receptor protein 2 0.0014 0.0214 0.0375
Leishmania major glucose transporter, lmgt1 0.0014 0.0223 0.3409
Trypanosoma brucei glucose transporter, putative 0.0014 0.0223 0.5848
Echinococcus granulosus sex peptide receptor 0.0018 0.0324 0.0324
Echinococcus multilocularis neuropeptide s receptor 0.0018 0.0324 0.0324
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0154 0.0335
Leishmania major glycerol uptake protein, putative 0.0008 0.0054 0.0533
Loa Loa (eye worm) hypothetical protein 0.0007 0.0048 0.0103
Leishmania major glycerol uptake protein, putative 0.0008 0.0054 0.0533
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0365 1
Echinococcus granulosus solute carrier family 22 0.0006 0.0023 0.0023
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0013 0.0203 0.1778
Schistosoma mansoni protein kinase 0.0013 0.0203 0.043
Brugia malayi Uncoordinated protein 44 0.0016 0.0274 0.048
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0365 0.583
Toxoplasma gondii sugar transporter ST1 0.0006 0.0023 0.0214
Brugia malayi Ras-related protein R-Ras2 0.0182 0.4603 0.8075
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0365 1
Onchocerca volvulus 0.0018 0.0324 0.0898
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0014 0.0214 0.0214
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0008 0.0054 0.0054
Echinococcus multilocularis insulin receptor 0.0049 0.1138 0.1138
Plasmodium vivax ataxin-2 like protein, putative 0.0008 0.0069 0.0456
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0109 0.2502
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.0324 0.0324
Echinococcus granulosus neuropeptide receptor 0.0018 0.0324 0.0324
Echinococcus granulosus somatostatin receptor 0.0018 0.0324 0.0324
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0018 0.0324 0.0704
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Mycobacterium ulcerans aldehyde dehydrogenase 0.0029 0.061 1
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0211 0.041
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0074 0.1776 0.3859
Echinococcus granulosus tachykinin peptides receptor 99D 0.0018 0.0324 0.0324
Loa Loa (eye worm) sugar transporter 0.0045 0.1037 0.2254
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Brugia malayi GnHR receptor homolog 0.0018 0.0324 0.0568
Echinococcus granulosus Immunoglobulin 0.0009 0.0103 0.0103
Loa Loa (eye worm) melatonin receptor type 1A 0.0018 0.0324 0.0704
Loa Loa (eye worm) hypothetical protein 0.0009 0.0103 0.0224
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0324 0.0686
Trypanosoma brucei THT1 - hexose transporter, putative 0.0014 0.0223 0.5848
Leishmania major protein kinase, putative 0.0013 0.0203 0.307
Brugia malayi jmjC domain containing protein 0.0011 0.0154 0.027
Plasmodium falciparum calcium-dependent protein kinase 1 0.0013 0.0203 0.1778
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0324 0.0324
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0029 0.061 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0324 0.0324
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0008 0.0054 0.0054
Echinococcus granulosus Ankyrin 0.0016 0.0277 0.0277
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0013 0.0203 0.0203
Brugia malayi MBOAT family protein 0.0008 0.0054 0.0095
Schistosoma mansoni transcription factor LCR-F1 0.005 0.1159 0.2455
Schistosoma mansoni opsin-like receptor 0.0018 0.0324 0.0686
Leishmania major glycerol uptake protein, putative 0.0008 0.0054 0.0533
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0112 0.2783 0.5999
Brugia malayi hypothetical protein 0.0006 0.0023 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0169 0.427
Entamoeba histolytica aminopeptidase, putative 0.0011 0.0151 0.0212
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0018 0.0324 0.0686
Loa Loa (eye worm) PHD-finger family protein 0.0009 0.0102 0.0223
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0008 0.0077 0.0077
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0013 0.0203 0.0203
Brugia malayi jmjC domain containing protein 0.0031 0.0661 0.1159
Echinococcus multilocularis General substrate transporter 0.0039 0.0871 0.0871
Schistosoma mansoni biogenic amine receptor 0.0018 0.0324 0.0686
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0011 0.0151 0.0151
Schistosoma mansoni histamine h1 receptor 0.0018 0.0324 0.0686
Echinococcus granulosus dna polymerase eta 0.0019 0.0356 0.0356
Echinococcus granulosus potassium voltage gated channel protein 0.0104 0.2563 0.2563
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Echinococcus granulosus aminopeptidase N 0.0011 0.0151 0.0151
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0008 0.0077 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0054 0.0068
Mycobacterium ulcerans aldehyde dehydrogenase 0.0029 0.061 1
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0223 0.5848
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Brugia malayi latrophilin 2 splice variant baaae 0.003 0.0627 0.1101
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0013 0.0203 0.0442
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0045 0.1037 0.1037
Treponema pallidum alginate O-acetylation protein (algI) 0.0008 0.0054 0.5
Echinococcus granulosus sterol O acyltransferase 1 0.0077 0.1876 0.1876
Schistosoma mansoni growth hormone secretagogue receptor 0.0018 0.0324 0.0686
Schistosoma mansoni adenoreceptor 0.0018 0.0324 0.0686
Echinococcus granulosus ras gtpase 0.0182 0.4603 0.4603
Loa Loa (eye worm) hypothetical protein 0.0006 0.0023 0.005
Echinococcus granulosus o acyltransferase membrane bound domain 0.0008 0.0054 0.0054
Trypanosoma brucei glucose transporter, putative 0.0014 0.0223 0.5848
Echinococcus multilocularis chromobox protein 1 0.0022 0.0443 0.0443
Leishmania major hypothetical protein, conserved 0.0008 0.0069 0.0787
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0011 0.0151 0.0151
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0013 0.0203 0.5266
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0223 0.0437
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0014 0.0211 0.0584
Schistosoma mansoni hypothetical protein 0.0018 0.0324 0.0686
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0324 0.0686
Schistosoma mansoni hypothetical protein 0.0014 0.0214 0.0452
Onchocerca volvulus 0.0006 0.0023 0.0064
Onchocerca volvulus 0.0018 0.0324 0.0898
Schistosoma mansoni hypothetical protein 0.0014 0.0214 0.0452
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0077 0.0164
Schistosoma mansoni tyrosine kinase 0.0049 0.1138 0.241
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0324 0.0324
Onchocerca volvulus 0.0006 0.0023 0.0064
Brugia malayi larval opioid receptor 0.0018 0.0324 0.0568
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Onchocerca volvulus 0.0018 0.0324 0.0898
Entamoeba histolytica hypothetical protein 0.005 0.1159 0.2429
Echinococcus multilocularis lysine specific demethylase 5A 0.0011 0.0154 0.0154
Schistosoma mansoni amine GPCR 0.0018 0.0324 0.0686
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0013 0.0203 0.0203
Schistosoma mansoni amine GPCR 0.0018 0.0324 0.0686
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0049 0.1138 0.1138
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0169 0.427
Trypanosoma brucei glucose transporter, putative 0.0014 0.0223 0.5848
Loa Loa (eye worm) hypothetical protein 0.0012 0.0169 0.0367
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0197 0.5081
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0014 0.0214 0.0214
Loa Loa (eye worm) major facilitator superfamily transporter 0.0006 0.0023 0.005
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.0324 0.0324
Echinococcus multilocularis conserved hypothetical protein 0.0309 0.792 0.792
Schistosoma mansoni tyrosine kinase 0.0152 0.3819 0.8087
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0009 0.0103 0.0103
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0008 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Schistosoma mansoni sugar transporter 0.0006 0.0023 0.0049
Schistosoma mansoni tyrosine kinase 0.008 0.1951 0.4132
Loa Loa (eye worm) hypothetical protein 0.015 0.378 0.8212
Echinococcus granulosus serotonin receptor 0.0018 0.0324 0.0324
Schistosoma mansoni voltage-gated potassium channel 0.0104 0.2563 0.5428
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0324 0.0324
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Schistosoma mansoni aldehyde dehydrogenase 0.0029 0.061 0.1292
Brugia malayi Immunoglobulin I-set domain containing protein 0.0009 0.0103 0.018
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0006 0.0007 0.0015
Brugia malayi hypothetical protein 0.0018 0.0324 0.0568
Leishmania major glucose transporter, lmgt2 0.0014 0.0223 0.3409
Leishmania major glycerol uptake protein, putative 0.0008 0.0054 0.0533
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0045 0.1037 0.1037
Echinococcus multilocularis potassium voltage gated channel protein 0.0008 0.0077 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0109 0.2502
Plasmodium vivax hexose transporter 0.0045 0.1037 1
Brugia malayi MBOAT family protein 0.0008 0.0054 0.0095
Echinococcus multilocularis epidermal growth factor receptor 0.0082 0.1996 0.1996
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0082 0.199 0.199
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0324 0.0324
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0006 0.0023 0.5
Onchocerca volvulus 0.0018 0.0324 0.0898
Echinococcus multilocularis synaptic vesicle 2 protein 0.0006 0.0023 0.0023
Schistosoma mansoni tyrosine kinase 0.008 0.1951 0.4132
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0008 0.0054 0.0118
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0354 0.062
Trypanosoma brucei glucose transporter 1E 0.0014 0.0223 0.5848
Brugia malayi Hhat protein 0.0008 0.0054 0.0095
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0008 0.0054 0.0054
Trypanosoma brucei Aminopeptidase M1, putative 0.0011 0.0151 0.3734
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0077 0.0164
Loa Loa (eye worm) hypothetical protein 0.003 0.0627 0.1363
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0186 0.0355
Trypanosoma brucei unspecified product 0.0017 0.031 0.8377
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Brugia malayi hypothetical protein 0.0008 0.0069 0.0122
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0008 0.0077 0.0077
Echinococcus multilocularis PHD finger protein rhinoceros 0.0009 0.0102 0.0102
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0018 0.0324 0.0704
Schistosoma mansoni protein kinase 0.0013 0.0203 0.043
Echinococcus multilocularis solute carrier family 22 0.0006 0.0023 0.0023
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0074 0.1776 0.1776
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0013 0.0203 0.0203
Echinococcus multilocularis Immunoglobulin 0.0009 0.0103 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0109 0.2502
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0008 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0018 0.0324 0.0704
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0364 0.079
Echinococcus multilocularis orexin receptor type 2 0.0018 0.0324 0.0324
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0013 0.0203 0.0203
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0324 0.0686
Echinococcus multilocularis shaker cognate 0.0008 0.0077 0.0077
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0186 0.4722 0.4722
Schistosoma mansoni opsin-like receptor 0.0018 0.0324 0.0686
Onchocerca volvulus 0.0006 0.0023 0.0064
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0324 0.0686
Schistosoma mansoni tyrosine kinase 0.0049 0.1138 0.241
Trypanosoma cruzi DNA polymerase eta, putative 0.0012 0.016 0.3995
Entamoeba histolytica protein kinase, putative 0.0013 0.0203 0.0327

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.2 uM Inhibition of human voltage-gated potassium channel subunit Kv1.5 expressed in Xenopus oocytes ChEMBL. 12570371
IC50 (binding) = 2.2 uM Inhibition of human voltage-gated potassium channel subunit Kv1.5 expressed in Xenopus oocytes ChEMBL. 12570371

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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